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Scientists Have 'Hacked Photosynthesis' To Boost Crop Growth By 40 Percent (npr.org)

An anonymous reader quotes a report from NPR: There's a big molecule, a protein, inside the leaves of most plants. It's called Rubisco, which is short for an actual chemical name that's very long and hard to remember. Rubisco has one job. It picks up carbon dioxide from the air, and it uses the carbon to make sugar molecules. It gets the energy to do this from the sun. This is photosynthesis, the process by which plants use sunlight to make food, a foundation of life on Earth. "But it has what we like to call one fatal flaw," Amanda Cavanagh, a biologist and post-doctoral researcher at the University of Illinois, says. Unfortunately, Rubisco isn't picky enough about what it grabs from the air. It also picks up oxygen. "When it does that, it makes a toxic compound, so the plant has to detoxify it."

Plants have a whole complicated chemical assembly line to carry out this detoxification, and the process uses up a lot of energy. This means the plant has less energy for making leaves, or food for us. Cavanagh and her colleagues in a research program called Realizing Increased Photosynthetic Efficiency (RIPE), which is based at the University of Illinois, have spent the last five years trying to fix Rubisco's problem. "We're sort of hacking photosynthesis," she says. They experimented with tobacco plants, just because tobacco is easy to work with. They inserted some new genes into these plants, which shut down the existing detoxification assembly line and set up a new one that's way more efficient. And they created super tobacco plants. "They grew faster, and they grew up to 40 percent bigger" than normal tobacco plants, Cavanagh says. These measurements were done both in greenhouses and open-air field plots.
The scientists are trying to apply this technique to other plants, like tomatoes, soybeans, and black-eyed peas, which are a staple food crop for a lot of farmers in sub-Saharan Africa. Cavanagh and her colleagues published their work this week in the journal Science.

34 of 280 comments (clear)

  1. Call it hacking by phantomfive · · Score: 5, Insightful

    Call it hacking and it's good, call it GMO and it's bad.

    "This one simple trick a woman discovered in her lab!"

    --
    "First they came for the slanderers and i said nothing."
    1. Re:Call it hacking by Gravis+Zero · · Score: 5, Insightful

      Call it hacking and it's good, call it GMO and it's bad.

      GMOs aren't bad, it's the modifications that are made that are bad.

      Growing faster with fewer resources = good modification.
      Able to resist being covered in increasingly caustic pesticides = bad modification.

      --
      Anons need not reply. Questions end with a question mark.
    2. Re:Call it hacking by novakyu · · Score: 2

      He just hates Monsanto (see: Roundup).

    3. Re:Call it hacking by Daemonik · · Score: 5, Insightful

      If only it were that simple. Frankly the paranoia and misinformation of liberals on the topic of GMO vs Organics is about as bad as conservatives and Global Warming.

      I've tried to explain to people that food irradiation is a safe method of preservation for instance, and been told that they don't want "radioactive" food. Explain to them that bananas are radioactive and they will, with a straight face, tell you that it's "natural" radiation so it's healthy. Try to explain that "organic" food uses some truly scary pesticides or that all foods have chemicals in them and it goes right over their heads.

      As far as GMO for Roundup goes, that stuff is expensive and nobody is out there replacing water with it like it's Brawndo. It's highly targeted spraying. However I do think that using GMO to lock seeds up behind copyrights and such is wrong. Modified life forms should be open source so we can all monitor and benefit from them equally.

    4. Re:Call it hacking by Daemonik · · Score: 2, Informative

      Able to resist being covered in increasingly caustic pesticides = bad modification.

      If they don't harm humans or the environment, is that a bad modification?

      Let's not go that far. Roundup (the most GMO targeted pesticide) is by definition a poison and does have ill effects on humans in concentration. It's all about the dose. It may also be linked to bee colony collapse, but I don't know if that's definitive. It's meant to kill insects so not really a shock if it is.

    5. Re:Call it hacking by Alwin+Henseler · · Score: 3, Informative

      If they don't harm humans or the environment, is that a bad modification?

      It is if that modification makes it easier to do so - as in Gravis Zero's example.

      Anyway I feel like science is moving towards a situation where DNA of all species currently on this planet serves as "software distribution v1.0", and where modified species are deployed at will to do some specific job. Kind of like how a carpenter picks a chisel or a hammer from his toolbox. Politics or public opinion aside, if it's technically possible & profitable, somebody will do it.

    6. Re:Call it hacking by ShanghaiBill · · Score: 4, Informative

      When you have companies trying to manufacture seedless versions of plants to replace the normal ones to the point they can potentially replace a sizable portion of our food supply with them and making us dependent on them

      RR seeds went off-patent in 2015. BT corn (maize) went off-patent in 2016.

      No other GMO crops are even close to a "sizable portion" of our food supply.

      Anyone is free to grow, save seed, whatever. Glyphosate (Roundup) is also off patent. Anyone can make it, and plenty of generics are available, even at Walmart.

      The "seedless" crops do produce seeds. What they don't produce is pollen. They use a "terminator gene" to block the spread of the genetic material. This is a GOOD THING, and it is also not used or sold anywhere because of protests by hypocritical environmentalists outraged that some of their best criticisms of GMO (pollen infecting neighboring farms, genes leaking into the wild) can be easily prevented. So instead of embracing the improvement, they fought to ban it.

    7. Re:Call it hacking by Anonymous Coward · · Score: 2, Funny

      Well, at least the researchers started this work on tobacco plants instead of food plants. It's not like the people consuming tobacco are really worried about taking up toxins, now are they?

    8. Re:Call it hacking by ShanghaiBill · · Score: 4, Informative

      Roundup (the most GMO targeted pesticide) is by definition a poison

      Roundup works by blocking a plant enzyme that does not exist in humans. So it is not "by definition" a poison to humans.

      and does have ill effects on humans in concentration. It's all about the dose.

      Sure. Distilled water also can have ill effects on humans. It's all about the dose.

      GMO crops generally reduce the need for herbicides and pesticides.

      The worst use of Roundup/glyphosate is as a crop desiccant, sprayed on green crops to dry them out shortly before harvest. This means the herbicide is on the crop as it is harvested. This is BY FAR the reason Americans are exposed to the most glyphosate. This practice is banned in many other countries.

      But guess what? It only works for crops that are NOT RR-GMO. So if you want to avoid glyphosate, don't buy any soy product that says "Non-GMO".

    9. Re: Call it hacking by Anonymous Coward · · Score: 5, Funny

      Bullshit they should be tithing their entire r&d budget to the church. Create food and water is a low level spell and since we are discussing fantasy, we should end up with clerics long before replicators let alone warp drive.

    10. Re:Call it hacking by 93+Escort+Wagon · · Score: 3, Insightful

      No other GMO crops are even close to a "sizable portion" of our food supply.

      The vast majority of US-grown soybeans are GMO.

      --
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    11. Re:Call it hacking by wierd_w · · Score: 2

      You missed the important part:

      They created a wholly new, artificial, antioxidant pathway. The gain in growth, is due to the increased efficiency of that new pathway.

    12. Re:Call it hacking by Daemonik · · Score: 3, Informative

      I don't want irradiated food because the radiation kills the plant. Dead food has far less nutritional benefits compared to fresh picked food that is still alive.

      Furthermore, if I can get non-irradiated food, I can plant the seeds and get my own copy of those plants to grow in my garden. In my opinion, THAT is the real reason why the ag industry wants to irradiate all of our food. It prevents propagation of desirable plant species, making people subservient to and reliant upon the ag industry.

      You know what? cooking food kills the plant, I don't see you advocating for all raw food, and if you are well, enjoy that salmonella. For that matter, taking a vegetable out of the ground or off it's tree/vine is slow killing it too. Which is neither here nor there because that's not how irradiation works.

      Also, hate to burst your conspiracy bubble, but farmers rarely sit around peeling apart last years crop to get seeds for this year. They buy seeds from dedicated seed farms, just like the majority of people who want a garden go down to the garden shop and buy packets of seeds. You get higher quality, more consistent seeds. Just because a fruit or vegetable is raw doesn't even mean it's in it's seed baring form either.

    13. Re: Call it hacking by Anonymous Coward · · Score: 3, Insightful

      I'll drink the same amount of glyphosate that it takes to kill a plant. That being, a 10th of an oz sprayed over a 30 acre field.

      If you want me to drink a cup of it, then I'm going to insist you drink a cup of something safe and natural, like salt

      (if you eat that much salt, it'll kill you)

    14. Re:Call it hacking by tomxor · · Score: 2

      Able to resist being covered in increasingly caustic pesticides = bad modification.

      If they don't harm humans or the environment, is that a bad modification?

      Really?.. Yes... because it encourages the use of caustic pesticides...

      Now I need to come up with some kind of quip orthogonal to "captain fucking obvious"

    15. Re:Call it hacking by coofercat · · Score: 2

      Growing faster with fewer resources = good modification.

      Maybe. Fast grown wood (like the faster growing pines) has its uses in our modern world, but is really a pretty crappy wood. Slow grown woods like oak obviously have far more uses. Even a slow grown pine has uses in more places and doesn't have the higher cost of the really slow growing trees.

      My point here is that growing faster with fewer resources may make a plant that looks like the slower growing variety, but it may not be as useful as it appears.

      Very few markets are really based on merit. They're skewed by artificial price manipulations, lobbying and laws and wonky business practices. The food market seems a particularly difficult one because of government approvals and tariffs, grants and subsidies, trade deals and whatnot. That means "the best" may not be what you can buy, even if you want to spend more to get it.

    16. Re:Call it hacking by Jason+Levine · · Score: 4, Insightful

      Nature is great, but it's not perfect. Not every improvement can be attempted by nature. Perhaps this new pathway was attempted by natural selection, but the partial pathway (as it wouldn't spring up completely finished in nature) didn't give enough of an improvement to be worthwhile. Or perhaps the partial path had a hidden cost that made it less able to compete. A cost that is overcome by the full pathway, but one that prevented natural selection from going down that road.

      Man has been artificially changing plants for thousands of years. Do you think apples looked like they do in the supermarket before man got his hands on them?

      --
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    17. Re:Call it hacking by Joey+Vegetables · · Score: 3, Informative

      Roundup works by blocking a plant enzyme that does not exist in humans. So it is not "by definition" a poison to humans

      Two huge flaws in your argument.

      1. We are symbiotic with our microbiome, much of which does have the shikimate pathway targeted by glyphosate. Therefore, it most assuredly, and emphatically, is a poison to humans, if we consume it in sufficient amounts to affect the microbiome. This is no longer even debatable or disputable. The ONLY question at this point is to what extent.

      2. Roundup does not consist solely of glyphosate. It contains other ingredients which increase both its effectiveness in its intended use, and also its toxicity, since what kills our microbiome more efficiently kills us more efficiently as well.

    18. Re:Call it hacking by wierd_w · · Score: 2

      The abstract gives more information:

      The pathway that was the most effective was a hybrid construct "used plant malate synthase and a green algal glycolate dehydrogenase"

      In other words, the components WERE produced by natural selection, but the combination does not occur in nature, and is novel in its efficacy.

      Full knockout of the endogenous pathway should remove the need for the RNAi used to keep that pathway suppressed, and should result in the >40% biomass increase across the board.

    19. Re:Call it hacking by jpaine619 · · Score: 2

      If it were really possible to increase the efficiency this much without any downsides, nature probably would have already stumbled upon it after all these billions of years. After all, a plant that can grow 40% bigger and faster than its predecessors would totally out compete and annihilate other plants vying for the same resources.

      Right... Prior to humans, wheat had really tiny seeds (in comparison to what we have today). We selectively bred wheat to have large kernels (more output per acre that way).. You see anyone dying from the runaway wheat? Is there anything that doesn't scare the shit out of you fucking luddites?

  2. Algae farms by Vanyle · · Score: 2

    It would be great if we could put this to use in something for generating bio-fuels.

    1. Re:Algae farms by Daemonik · · Score: 4, Interesting

      Unfortunately it will probably work out that rather than produce more food, which will subsequently lower food prices, they'll devote more land to growing high starch corn for bio-fuel.

      Bio-fuel is a nice idea, but currently there are too many down sides and loopholes to relying on it that most people don't consider. It's like how paper mills have used black liquor, a byproduct of paper production, for decades as fuel in the plants. Then they mixed in a gallon of diesel, called it 'biofuel' and raked in billions from biofuel subsidies.

    2. Re:Algae farms by codeButcher · · Score: 2

      It would be great if we could put this to use in something for generating bio-fuels.

      Unfortunately it will probably work out that rather than produce more food, which will subsequently lower food prices, they'll devote more land to growing high starch corn for bio-fuel.

      The good and bad news for both of you is that corn is one of the plants that already uses the more-efficient C4 pathway...

      --
      Free, as in your money being freed from the confines of your account.
  3. Re:LOL by jfdavis668 · · Score: 2

    Probably invented Tomacco. The Simpson's will be suing them for copyright violation.

  4. Photosynthesis is complex by aberglas · · Score: 5, Interesting

    There is a light dependent reaction that creates ATP, which is the energy source for the light independent Calvin cycle which actually reduces CO2.

    https://en.wikipedia.org/wiki/...

    I am not sure what they have hacked, but it is more complex than the summary suggests. And it would be an amazing achievement to be able to improve a system perfected by 4 billion years of evolution without any down side. I suspect there is a downside, maybe a need for more water etc.

    Well done anyway, if true.

    1. Re:Photosynthesis is complex by belg4mit · · Score: 5, Insightful

      Evolution hasn't perfected anything,* it is a fundamentally conservative process circuit-bending existing hardware and occasionally developing something new. If changes help, they spread, if they hurt, their prevalence diminishes but rarely to zero, and if they're neutral they persist as well. Hardly the features of something that's guaranteed to make the best thing possible, but rather, like many software developers, something that's just good enough :-P

      * A standard example being laryngeal nerves in giraffes.

      --
      Were that I say, pancakes?
  5. 4 billion years of evolution doesn't necessarilly by rsilvergun · · Score: 5, Insightful

    make the best thing. It makes the most successful thing among other things, but that's not "best". Ever wonder why we get scurvy? We have a defective gene that prevents us from making Vitamin C. We compensated in other ways, but that doesn't mean we're the "best", just better than the alternatives.

    Same deal here. Think of all the energy wasted out there and imagine if we didn't waste it. Look at bananas. They start out barely edible and end up as convenient as anything you'd buy in a plastic bag.

    Now, there are potential downsides to a mono-culture, but then if we can tweak genes at will we don't have to have a mono-culture, do we?

    --
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  6. Re:preliminary findings by Luckyo · · Score: 4, Insightful

    There are two reasons why you're wrong:

    1. Mutation can miss many optimal routes due it it being overwhelmingly a minor step-by-step process rather than a massive leap. Evolution works as relative competition against others. If no one has this change, you don't have to compete against it. And if they have to literally replace the entire system with another, chance of evolution developing it is not all that high. This is because developing such a system as a random sequence of mutations would be a very costly thing, while having to maintain the old system until the new one is fully evolved.

    2. The mutation might actually have significant long term weakening of the plant itself against some competition, where it would need cultivation by another much more powerful species to make it an evolutionary winner. I.e. agriculture.

  7. And here it is by SuperKendall · · Score: 5, Informative

    I find it a bit amusing that you proceeded to ALSO not give us the actual name despite complaint...

    It is:

    Ribulose-1,5-bisphosphate carboxylase/oxygenase

    I agree, it was not THAT long. Probably whatever grammar checker system they had refused to let it pass. Or like you say he was just lazy and thought all his readers were morons. Either way, not a good look.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley
  8. Re:preliminary findings by zilym · · Score: 4, Informative

    Some plants HAVE evolved ways of improving CO2 capture. It's just that the vast majority of the food crops people desire to eat are still using the old mechanism. Do some research on C3 vs. C4 and CAM photosythesis. Corn is one of the few food crops that uses the newer C4 photosynthesis engine. Corn's productivity is likely one reason why pretty much all of our cheap junk food today contains corn in some form or another.

  9. Re:preliminary findings by ShanghaiBill · · Score: 5, Informative

    Some plants HAVE evolved ways of improving CO2 capture.

    The evolution of the C4 pathway happened in grasses, and they spread around the world about 6-7 million years ago. Tropical savanna replaced woodland in Africa, as the grasses outcompeted forests via more efficient photosynthesis. Hominids moved out of the forest into the expanding savanna, learning to walk upright, freeing up their hands to use tools.

    The C4 pathway also meant plants could pull more CO2 out of the atmosphere, lowering global temperatures. The spread of C4-capable grasses may have been the main trigger for the ice ages.

    Corn is one of the few food crops that uses the newer C4 photosynthesis engine.

    Another big C4 crop is sugar cane. Millet and sorghum are also C4.

  10. Re: preliminary findings by Shotgun · · Score: 2

    There is also an assumption that being 40% larger is an ecological benefit.

    --
    Aah, change is good. -- Rafiki
    Yeah, but it ain't easy. -- Simba
  11. Re: preliminary findings by malkavian · · Score: 2

    Species generally don't give a crap about ecology. They do what's in the interests of their species. Plants evolve traits that give them the best shot at the environment they grow in. Animals do exactly the same.
    Every single species on the planet affects the ecology in some way, just humans have found a way to affect it the most.
    If you get a 40% increase in biomass for the same investment in various pesticides, herbicides and general land use, you can either increase your production (if there's a market for it), or decrease the rate at which new land is required to maintain food production for the population (allowing the 'natural' ecosystems to last longer).
    So I'd say there's a definitely ecological benefit.

  12. Re:preliminary findings by Luckyo · · Score: 2

    Then you should take off the "I don't understand this argument because you're an idiot" glasses and put the "I don't understand this argument because I'm an idiot" ones.

    Because you need not look beyond human gestation process to see exactly what I was talking about here. There's a clear cut evolutionary reason why the process of development effectively starts humans as fish with gills, that get apoptized as we slowly progress to something that resembles a mammal. Evolution does not build new systems as a matter of rule, and exceptions to this are extremely rare. It instead adds to existing ones, which is why humans still contain the genetic code to begin gestating as a fish.

    The system being talked about here is a completely new system that would entirely replace the old one. Evolution is very bad at generating such systems.