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Common Weed Killer Glyphosate Increases Risk of Cancer By 41 Percent, Study Says (theguardian.com)

A broad new scientific analysis of the cancer-causing potential of glyphosate herbicides, the most widely used weedkilling products in the world, has found that people with high exposures to the popular pesticides have a 41% increased risk of developing a type of cancer called non-Hodgkin lymphoma. The Guardian reports: The evidence "supports a compelling link" between exposures to glyphosate-based herbicides and increased risk for non-Hodgkin lymphoma (NHL), the authors concluded, though they said the specific numerical risk estimates should be interpreted with caution. Monsanto maintains there is no legitimate scientific research showing a definitive association between glyphosate and NHL or any type of cancer. Company officials say the EPA's finding that glyphosate is "not likely" to cause cancer is backed by hundreds of studies finding no such connection.

But the new analysis could potentially complicate Monsanto's defense of its top-selling herbicide. Three of the study authors were tapped by the EPA as board members for a 2016 scientific advisory panel on glyphosate. The new paper was published by the journal Mutation Research /Reviews in Mutation Research, whose editor in chief is EPA scientist David DeMarini. [...] The study authors said their new meta-analysis evaluated all published human studies, including a 2018 updated government-funded study known as the Agricultural Health Study (AHS). Monsanto has cited the updated AHS study as proving that there is no tie between glyphosate and NHL. In conducting the new meta-analysis, the researchers said they focused on the highest exposed group in each study because those individuals would be most likely to have an elevated risk if in fact glyphosate herbicides cause NHL.

24 of 162 comments (clear)

  1. I'll just leave this here. by Jack9 · · Score: 4, Funny
    --

    Often wrong but never in doubt.
    I am Jack9.
    Everyone knows me.
    1. Re:I'll just leave this here. by dirk · · Score: 3, Insightful

      There are a lot of things that are safe for me to drink but there is no way I would drink them. My own urine is safe for me to drink, but if you want me to drink it I'm going to have the same response as this guy. I know play doh is safe to eat, but if you ask me if I want to eat a jar of it, I'm going ot tell you know because I'm not an idiot. That doesn't make it unsafe, that makes your request stupid.

      --

      "Information wants to be expensive" - Stewart Brand, the same guy who said "Information wants to be free"
    2. Re:I'll just leave this here. by PopeRatzo · · Score: 3, Insightful

      It is totally unreasonable for you to decline to drink a liquid that we say is your product, even if it is an industrial chemical produced and bottled on an assembly line that wasn't designed, cleaned or inspected for producing products intended for human consumption.

      It depends entirely on whether I went around in previous interviews touting the fact that my product was safe enough to drink.

      In that case, saying, "OK, let see you do it," is a reasonable request. Especially if the product is going to be used on a basic foodstuff that is in practically everything people eat.

      --
      You are welcome on my lawn.
    3. Re:I'll just leave this here. by N1AK · · Score: 2

      Excrement is used on a basic food stuff, it doesn't mean it's part of a healthy and balanced diet.

      This logic that the only way to back up claims something is safe to drink is to drink it anytime someone asks is ridiculous. If someone wants to sell a medical product that can cure a disease do they have to infect themselves with the disease each time someone asks just to prove they "really" believe it?

    4. Re:I'll just leave this here. by danbert8 · · Score: 4, Insightful

      Poop is a common fertilizer in "organic" farming, yet it is not safe to consume. I don't see why being able to drink something used in agriculture is any sort of standard for safety.

      --
      Yes it's an anecdote! Were you expecting original research in a Slashdot comment?
  2. Relative risk by Smidge204 · · Score: 5, Informative

    That's 41% relative increase. This means that if you take two people who have an equal chance of getting this cancer, and one is given a "high exposure," they are now 41% more likely to get this cancer than the other, unexposed person.

    So if *everyone* got a "high exposure" the rate of this particular form of cancer would increase from 19.4 per 100,000 to 27.4 per 100,000.

    That's still an eye-raising increase, but try to keep it in perspective. This does NOT mean 41% of people exposed get cancer.
    =Smidge=

    1. Re: Relative risk by TimMD909 · · Score: 5, Funny

      You're not doing outrage and sensationalism right... Try using more hyperbole and mention how it affects certain groups more than others. Thanks. - Mass Media

    2. Re: Relative risk by alvinrod · · Score: 4, Informative

      Well it does affect certain groups more than others. Only the highly exposed are at risk.

      I'm sure if I click through enough links I'll eventually be able to find out whether highly exposed means you had to bathe in the shit or something like that, but is high exposure in the context of these results a practical concern for anyone who isn't working directly with the product?

    3. Re: Relative risk by reanjr · · Score: 3, Interesting

      Is it ok if Monsanto is only poisoning farmers?

    4. Re: Relative risk by sjames · · Score: 5, Insightful

      Well, lawncare companies often apply it on commercial and residential lawns (not to the grass itself, of course). If you just work at the company, probably no worries. If you are a kid that plays in the yard, you might get more exposure than the people who apply the stuff.

    5. Re: Relative risk by ShanghaiBill · · Score: 4, Insightful

      Is it ok if Monsanto is only poisoning farmers?

      If the overall risk is lower than using alternative herbicides, then yes.

      Glyphosate is a very effective herbicide that increases crop yields, is safer to handle than the broad spectrum herbicides it replaced, and enables no-till farming methods that reduce soil erosion and increase soil carbon retention.

      We need to develop better equipment and techniques to handle it properly, and educate farmers on those techniques. But glyphosate is unlikely to be discontinued.

    6. Re: Relative risk by K.+S.+Kyosuke · · Score: 2

      The instructions on my bottle specifically say not to let your kids and pets play in a treated yard for 72H.

      So basically, the instructions are "round up your kids", not "Roundup your kids"?

      --
      Ezekiel 23:20
    7. Re: Relative risk by chaotixx · · Score: 2

      How, I wonder, did human beings raise crops for thousands of years before herbicides, insecticides and artificial fertilizers were invented?

      Much less efficiently.

  3. Interesting how we never hear about these things by Anonymous Coward · · Score: 3, Interesting

    ... until after the patents have expired.

    Monsanto had 26 years of selling Roundup with no 'generic' glyphosate competition. In that time, not a word was published about carcinogenic properties.

    But for the past 15 years or so, these stories have been dribbling out, and now they're becoming a flood. It's almost as if someone wanted to discredit the now-generic product in favor of a newer, still-patented alternative.

  4. Difference in amount becomes difference in kind by Miamicanes · · Score: 5, Insightful

    Key phrase: "people with high exposures to the popular pesticides"

    On a related note, inhaled dihydrogen monoxide can be fatal and cause death within minutes without prompt medical assistance.

    1. Re:Difference in amount becomes difference in kind by Anonymous Coward · · Score: 5, Insightful

      Key phrase: "people with high exposures to the popular pesticides"

      On a related note, inhaled dihydrogen monoxide can be fatal and cause death within minutes without prompt medical assistance.

      Additionally, you have to be very careful when you select subsets. For instance, what if the people that get the highest exposure are just being generally unsafe with pesticides, smoking, etc and they also get a high exposure of a bunch of other stuff. By selecting a subset of a data, you may inadvertently be selecting for something else, such as risky behavior in general.

      Personally I wouldn't stop using it, but I'd take reasonable precautions, like gloves, washing, and if in doubt immediately shower afterward. Then again, if your handling a chemical that makes something else not grow or die, common sense says be careful with it.

      The other question I didn't see an answer to, is what do you have to do to get the highest exposure? If your throwing around a figure like 41%, you should say well people with this exposure typically got it by ...

    2. Re:Difference in amount becomes difference in kind by wildchild07770 · · Score: 2

      That was my MAIN question and conspicuously absent definition. What did they consider "high", and also discounting correlated confounds that may have missed the validity how small did the N get when they filtered down to these "high exposure" people. You can get surprisingly significant results that are actually just random nose but from an (un) lucky confidence your small sample you're results.

    3. Re:Difference in amount becomes difference in kind by JBMcB · · Score: 2, Informative

      The other question I didn't see an answer to, is what do you have to do to get the highest exposure? If your throwing around a figure like 41%, you should say well people with this exposure typically got it by ...

      Inhaling it in aerosol form on a regular basis. The first study that showed a correlation between glyphosate exposure and cancer looked at Spanish farm-workers who sprayed the stuff on their crops regularly and didn't wear a respirator.

      So, if there is really a correlation, you have to be exposed to quite a bit of the stuff to make a statistical difference. Spraying it around your yard every once in a while probably won't make a difference.

      --
      My Other Computer Is A Data General Nova III.
  5. Your stats are from where...? by DogDude · · Score: 4, Informative

    Where did you get your stats? The actual incidence of this kind of cancer is closer to 2.4% for men and 1.9% for women. (https://www.cancer.org/cancer/non-hodgkin-lymphoma/about/key-statistics.html). That means that exposure to glycophosphate increases it to 3.38% and 2.68%, respectively. That's about an extra 1/100 people. 41% in this case seems to be pretty damn significant.

    --
    I don't respond to AC's.
  6. Re:Need At Least Three Answers To Care by will_die · · Score: 2

    According to the paper they did not. They took 5 other studies that did not show an increased risk. Then they took only the very highest people from each report, and which varied by each of the previous studies, and compared them to those not in the high exposure and got a 41% increase. In other part of the report they did show that prolonged exposure to 100% glyphosate raised the rate of increase; round up is 18%.

  7. Re:Amazing... by Derekloffin · · Score: 4, Informative

    I suspect many are defensive on this as this topic is littered with misinformation from activists. This isn't the first study to come out against it, but I hesitate to call those studies as they were basically propaganda that didn't hold up on closer inspection. I've already seen enough here on this study to highly question it and I have no horses in this race.

  8. Re:Data required by Shinobi · · Score: 2

    Because you may be able to discern a pattern that is not revealed in any single isolated study. To turn around an old folk saying, instead of seeing individual trees, you suddenly start seeing a forest. Each tree will still be its own entity, but you suddenly have a large pattern that each individual tree didn't provide a clue for.

    There was something similar in clinical psychology and in psychiatry a few years back, regarding autism. A team performed a meta-study of various autism studies, and found a pattern of across-the-board reduced life expectancy for people with autism, around 5 years lower than the global average life expectancy. None of the individual studies had shown a hint at such a large pattern, but all of a sudden there it is. None of the follow-up studies currently being done is showing any signs of refuting that. If anything, it looks like it will get worse, as we get more data from less developed nations.

  9. Re:Data required by Antique+Geekmeister · · Score: 2

    Meta analysis of other studies are _extremely_ dangerous. They can be much cheaper, and are much more easily distorted, than collecting real data with detectable, reproducible results. To cite your own example, are any of the newer studies actually measuring life expectancy for people with and without autism? Or are they also meta-analyses, receiving funding becuase the contemporary fascination with autism? And since the definition of autism has been malleable, and the rate of diagnosis of it has effectively doubled between 2000 and 2014 according to the CDC at https://www.cdc.gov/ncbddd/aut... , how has that distorted the results?

  10. tobacco industry playbook by sad_ · · Score: 2, Insightful

    i see monsanto has been reading the old tobacco industries playbook and how they handled the cancer claims (until they no longer could).

    --
    On a long enough timeline, the survival rate for everyone drops to zero.