they use a mix of anesthetic and the capsaicin so that you'r not in horrible pain. The nerves are over-stimulated in a way, this leads to them being numbed [like after eating too many spicy peppers] and it has already been used as a topical treatment for pain, I think there's even one pain treatment available to the public already based on this.
The problem with citizendium is the basic premise that the masses aren't "qualified" to contribute. This is what made the wikipedia so much fun-- all of us dilletantes had a place to put in our smattering of knolwedge about history, geography, or punk rock.
A lot of knowledge is available to the masses that doesn't require higher education. The problem is when people start contributing "information" when they 1) have none of the real world experience/knowledge needed to contribute useful knowledge. 2) FUD [take a look at the page comparing OSes specifically Windows and Linux, lots of FUD there] not that an expert would remove that kind of bias entirely, but there would likely be a lot more in the way of cold hard facts than a personal bias.
But only a minority of the population graduates college, and an even smaller minority have the advanced degree in place to be a qualified 'authority' to speak authoritatively on a given subject.
that's a tad disturbing isn't it? people speaking on a subject they have no idea about or the qualifications?
Might the Web 2.0 umbrella be expanded to include real name requirements and roles for experts? It's looking that way."
That doesn't have any more of a chance than Slashdot doing that. The only thing that I can see causing the entirety of the "Web2.0" projects adopting such a system is through new restirctive laws passed by many governments across the world. Proably under the guise of preventing terrorism or some other nonsense.
vinyl's niche is very different than digital/cd's niche. To say that vinyl is the end of cd's is inaccurate at the very least. there will still be people that buy vinyl used or not and people who prefer digitized formats for whatever reasons they may be. Unless vinyl can somehow outcompete digital tracks on storage and portability I don't see them dooming cds any time soon.
People think of their computer much like a toaster or their microwave. They have no idea how it works, they have no wish to know how it works anymore than they would their microwave. It's very disturbing really, that the vast majority of people have absolutely no idea how any part of their computer works... It is entirely due to everything being done for them. Look at how windows is normally set up- they don't need to know how to install it. If anything goes wrong they buy a new computer instead of fixing it. Windows software is bundled with the OS, Internet Explorer, Word, Excel etc. though most of those are trials which inevitably people end up buying MS office because they don't bother to find anything else. People like routine, even if they end up doing a lot more work in the end getting Windows to do what they want, it is what they know. No amount of scolding on we geek's part will change that unless something makes them realise the needless hassle they had to endure dealing with proprietary software. chances of that happening? If the EU actually starts kicking MS's ass once in a while that may actually happen. Not much of a chance of it happening here though.
Yes, Augmentin is one specific case of a comination of a beta-lactamase inhibitor and a penicillin-like drug [amoxicillin in this case] It is only one of many but that is exactly the kind of drug combo the article is talking about. Unfortunately there are already signs that even this combo is starting to select for drug resistance.
bacteria can be fought nearly indefinitely by bacteriophages which evolve along side the bacteria in a never ending arms race, viruses are far trickier than that. Viruses evolve on very short timespans exceeding bacteria's rate of evolution in many cases so if there's something to fear it's them. Although even HIV has a weakness, one significant one has already been found in populations in Africa. It's an altered gene to be precise, one that alters a cell receptor on the outside of our cells that is a key site for HIV to bind to and gain access to the cell.
their research works on similar principles to the slashdot article although they work by very different pathways. The slashdot article is about a [penicillin degrading enzyme] inhibitor; penicillin inhibits cell wall synthesis which kills gram-positive bacteria. The research page you linked is about developing inhibitors to several amino acid/nutrient pathways that are common in these kind of bacteria but are very different than the pathway(s) penicillin acts on.
It's a beta-lactamase inhibitor, it stops beta-lactamase from cleaving the 4 atom ring of penicillin-like drugs. This ring is very important in the function of Penicillin which actually prevents the building of cell walls in gram-positive bacteria. these bacteria need a thick cell wall to keep from bursting. this drug in of its self does little, only combined with penicillins does it revive the drug's germ killing power.
http://en.wikipedia.org/wiki/Clavulanate
agreed, she made a far bigger mess of it than it should have been. what has my attention is that she says
I didn't like feeling that I could get in trouble for something as simple as posting a home video for my friends and family to see.'"
when she could have just as easily sent a copy to her friends/family privately she chose to post it on a public high volume internet video site like youtube that in all likliness will be seen by thousands of people at the least. it almost sounds like she way trying to grab herself a lot of attention from the whole thing when it wasn't at all necessary.
One question I don't have an answer for is, how can scientists reliably speculate the state of this earth millions or billions of years ago with the evidence we have now, in this day and age? I can't see how that is feasibly possible, without basing it around assumptions or belief.
We can reliably "speculate" on things that happened in Earth's geological history in part ebcause of the sheer volume of fossils, rocks, strata, genetic evidence, molecular modeling, nuclear dating, ice cores, etc... there are many many different ways to determine the age of rocks, the conditions at the time and the lineage of species. The vast majority of scientific studies use several seperate lines of evidence to confirm or rule out previous findings. The measurment of the age of the Earth for example is based on hundreds of samples, at least 3 or 4 nuclear dating methods for each sample and many many repititions for each. We've got more evidence for evolutionary lineages and geology than we do for gravity, that should tell you something.
So, faith in chance is better than faith in tradition and personal experience. Interesting perspective. I hope it brings joy and peace to your life.
The use of logic will always be superior to blind faith in a book. The fact you feel warm and fuzzy because you believe in magic does not change reality in the slightest. Things either exist or they don't there is no "it makes me happy to believe it exists so it does and to hell with anyone who thinks otherwise" /rant
Cosmological theories are currently not much better than intelligent design - you just have to take them on faith.
except string theory is based on some very complicated math and heavily encrusted in physics, intelligent design on the other hand is an attempt to justify the writings of biblical authors over 2,000 years ago there is a clear difference.
Different versions of the string theory can not even agree on the number of physical dimensions that exists. They are basically just playing with numbers to try to match the observed strength of gravity.
after you do the math it works out that if you don't have supersymmetry you need precisely 26 dimensions to fit what we observe, with supersymmetry you only need 10 or 11, the 11th unique to M-theory seems to explain phenomenae predicted by the 5 major string theories common a few years ago. it does make predictions although at the moment the number that we can test are very small, this will change as we get better at observing higher energy events and work out more of the math.
Not to mention that our existing physics only explains 10% of gravity in the universe. Talk all you want about dark matter, but this leaves the possibility of pretty dramatic flaws in our current theories.
except that we have observed objects in the universe that seem to have wrenched dark matter out into the open, free of most of the visible matter. we still see the gravitational lensing effect of this matter which allows us in effect to map dark matter in that region.
The biggest flaw in current cosmology is why we are not trapped in a singularity of a universe-mass black hole. Certainly for long time after big bang the universe was inside its own Schwarzschild Radius. Why didn't it just collapse right back after the big bang? After all, it would take an infinite force to escape the event horizon. Oh right, something caused "space" to mysteriously expand, just like now some unspecified dark matter keeps stuff from expanding. It sounds like we need more work to get to the standard of scientific theories.
space is in fact expanding, not only that but the expansion is accellerating over time. space isn't theoretically expanding, it litterally is expanding at great velocity. although at the same time, there is growing evidence that certain higher dimensional phenomenae could be responsible for this expansion and even the kind that caused the big bang [if causality even means anything at that point] but there is a very important thing to learn here, there is never ever an infinite force, there is a limit to the magnitude of a force, gravity is likely to be quantised as well, which probably means that there is a finite limit to spatial curvature. the concept of an infinitely dense mass may also not even exist if there is a finite quantised limit to spatial curvature. we have a few years or less before we can start really testing some of the predictions of quantum gravity and string theory in general, if we're wrong, we learned from it and can better understand the universe because of it.
I agree with you on that point, the theory(s) isn't very well proven for or against yet although the logic that goes into its construction is very much worth mentioning. string theory its self in all likliness is incorrect to some degree although it could very well inspire something better.
that is correct, it seems to be more of a formality. in fact, it really can't be pinned down to a finite position or even a real "shape", its wavefunction is smeared across space. there is a finite proability of it being in a certain position at any given time just like electrons "going around" an atom. these strings can even "tunnel" bridging gaps that mathematically have exactly zero probability of the particle being there. an example of this is the electron cloud in p-orbitals in a Benzene ring. there is exactly zero electron density between the top p-orbital overlap ring and the lower one and yet electrons constantly interchange between the two in less than a trillionth of a second.
blackholes exhibit peculiar behavior that can more easily be described by equations more fit in higher dimensional space in regard to spin and charge. higher dimensions have very interesting theoretical consequences [altered gravitational constants, mini blackholes accessible to high energy particle accelerators etc.] although theoretically these dimensions fold back on themselves so these "strings" are wrapped as well because their geoetry must also follow the space in which they inhabit.
string theory in less than a paragraph. strings "vibrate" in higher dimensional space. [specifically M-theory suggests 11 dimensions] energy states are quantised, including mass at some level. String theory's ultimate goal is to eliminate infinities and non-sensical probabilities that result from the current standard model. Also, at some level the forces merge into a single force, this force splits at lower energies which may cause some very interesting phenomenae [spatial expansion for one] one of the major hurdles to string theory is gravity. why is it as weak as it is? what are the consequences of higher dimensions to its relative strength etc. [even some theoretical work suggests gravitons leak between dimensions] very little of it is testable at the moment, one major prediction that could in principle be tested is that of varying velocities of photons according to energy/wavelength. the models suggest that a lag of around a minute or less over a distance of several billion light years while this isn't unique to string theory.
the particles generally range from dust sized to very large objects much larger than a house and jusging from how much space the rings occupy, it should still be pretty empty in comparison to cluttered debris fields in movies.
with that many tabs, it would be easiest to just witch to another tab, especially if you already renamed the tabs/hid their names to your liking. of course shutting off the monitor works too
meh. alt f4 closes my firefox in less than 1/4 a second accourding to my research. then again, having the taskbar set to close a window on middle click and the ability to minimize all windows nearly instantaneously helps too.
"But a USPTO report earlier this year stirred up the issue again by claiming that P2P installs could adversely affect national security when they made confidential government information available. This has already happened several times
There are a lot of other ways information gets around, it isn't all P2P and even if it was, that isn't their problem. The idea that you can stop information flow any more is in the realm of the insane.
Slashdot Mirror
yes but this is particular was my lame attempt to be funny :(
well ya if you had capsaicin flowing up there you'd pee yourself too.
they use a mix of anesthetic and the capsaicin so that you'r not in horrible pain. The nerves are over-stimulated in a way, this leads to them being numbed [like after eating too many spicy peppers] and it has already been used as a topical treatment for pain, I think there's even one pain treatment available to the public already based on this.
yep, buzzwords like "web2.0" are just code for "vaporware" or any eqivalent
vinyl's niche is very different than digital/cd's niche. To say that vinyl is the end of cd's is inaccurate at the very least. there will still be people that buy vinyl used or not and people who prefer digitized formats for whatever reasons they may be. Unless vinyl can somehow outcompete digital tracks on storage and portability I don't see them dooming cds any time soon.
People think of their computer much like a toaster or their microwave. They have no idea how it works, they have no wish to know how it works anymore than they would their microwave. It's very disturbing really, that the vast majority of people have absolutely no idea how any part of their computer works... It is entirely due to everything being done for them. Look at how windows is normally set up- they don't need to know how to install it. If anything goes wrong they buy a new computer instead of fixing it. Windows software is bundled with the OS, Internet Explorer, Word, Excel etc. though most of those are trials which inevitably people end up buying MS office because they don't bother to find anything else. People like routine, even if they end up doing a lot more work in the end getting Windows to do what they want, it is what they know. No amount of scolding on we geek's part will change that unless something makes them realise the needless hassle they had to endure dealing with proprietary software. chances of that happening? If the EU actually starts kicking MS's ass once in a while that may actually happen. Not much of a chance of it happening here though.
Yes, Augmentin is one specific case of a comination of a beta-lactamase inhibitor and a penicillin-like drug [amoxicillin in this case] It is only one of many but that is exactly the kind of drug combo the article is talking about. Unfortunately there are already signs that even this combo is starting to select for drug resistance.
bacteria can be fought nearly indefinitely by bacteriophages which evolve along side the bacteria in a never ending arms race, viruses are far trickier than that. Viruses evolve on very short timespans exceeding bacteria's rate of evolution in many cases so if there's something to fear it's them. Although even HIV has a weakness, one significant one has already been found in populations in Africa. It's an altered gene to be precise, one that alters a cell receptor on the outside of our cells that is a key site for HIV to bind to and gain access to the cell.
their research works on similar principles to the slashdot article although they work by very different pathways. The slashdot article is about a [penicillin degrading enzyme] inhibitor; penicillin inhibits cell wall synthesis which kills gram-positive bacteria. The research page you linked is about developing inhibitors to several amino acid/nutrient pathways that are common in these kind of bacteria but are very different than the pathway(s) penicillin acts on.
It's a beta-lactamase inhibitor, it stops beta-lactamase from cleaving the 4 atom ring of penicillin-like drugs. This ring is very important in the function of Penicillin which actually prevents the building of cell walls in gram-positive bacteria. these bacteria need a thick cell wall to keep from bursting. this drug in of its self does little, only combined with penicillins does it revive the drug's germ killing power.
http://en.wikipedia.org/wiki/Clavulanate
/rant
I agree with you on that point, the theory(s) isn't very well proven for or against yet although the logic that goes into its construction is very much worth mentioning. string theory its self in all likliness is incorrect to some degree although it could very well inspire something better.
yes, it is a way to test string theory although most of the GRB events I've heard of didn't have enough data to say either way.
that is correct, it seems to be more of a formality. in fact, it really can't be pinned down to a finite position or even a real "shape", its wavefunction is smeared across space. there is a finite proability of it being in a certain position at any given time just like electrons "going around" an atom. these strings can even "tunnel" bridging gaps that mathematically have exactly zero probability of the particle being there. an example of this is the electron cloud in p-orbitals in a Benzene ring. there is exactly zero electron density between the top p-orbital overlap ring and the lower one and yet electrons constantly interchange between the two in less than a trillionth of a second. blackholes exhibit peculiar behavior that can more easily be described by equations more fit in higher dimensional space in regard to spin and charge. higher dimensions have very interesting theoretical consequences [altered gravitational constants, mini blackholes accessible to high energy particle accelerators etc.] although theoretically these dimensions fold back on themselves so these "strings" are wrapped as well because their geoetry must also follow the space in which they inhabit.
string theory in less than a paragraph. strings "vibrate" in higher dimensional space. [specifically M-theory suggests 11 dimensions] energy states are quantised, including mass at some level. String theory's ultimate goal is to eliminate infinities and non-sensical probabilities that result from the current standard model. Also, at some level the forces merge into a single force, this force splits at lower energies which may cause some very interesting phenomenae [spatial expansion for one] one of the major hurdles to string theory is gravity. why is it as weak as it is? what are the consequences of higher dimensions to its relative strength etc. [even some theoretical work suggests gravitons leak between dimensions] very little of it is testable at the moment, one major prediction that could in principle be tested is that of varying velocities of photons according to energy/wavelength. the models suggest that a lag of around a minute or less over a distance of several billion light years while this isn't unique to string theory.
the particles generally range from dust sized to very large objects much larger than a house and jusging from how much space the rings occupy, it should still be pretty empty in comparison to cluttered debris fields in movies.
with that many tabs, it would be easiest to just witch to another tab, especially if you already renamed the tabs/hid their names to your liking. of course shutting off the monitor works too
meh. alt f4 closes my firefox in less than 1/4 a second accourding to my research. then again, having the taskbar set to close a window on middle click and the ability to minimize all windows nearly instantaneously helps too.
and the rest of us know our hotkeys. :) alt tab, alt f4, ctrl t and any number of others with modified kde shortcuts