My first paper in chemistry was submitted to the Journal of the American Chemical Society. The review took over a year. This was before the internet and the editor dropped the ball. At that time, it was bad form to ask the editor about the status of your submission as the process was already slow and you did not want to pester the editor and get it treated more slowly. Email has changed the whole process, but some journals are still slow.
Machine learning does not even give a hint on causality. It can glean properties from the training data, but does not even give a hint of what parts of the training data lead to the outcome. Without causality, these data cannot be used to create new data points that have the desired outcome. It is more of a shotgun approach, train on know data sets and then blast related data points to see of they may have properties related to the trained data sets. I have tried to make this generic, but there are clear examples on the literature where the machine learning can identify properties of the data set better than many theories, but the resuolt can not be used to design new thing that have the desired properties.
Some kind of preservative is needed. Deuterium oxide could be use to preserve vaccines as it is by definition sterile and microbes cannot grow in it without extensive adaptation. Additionally, D2O reduces protein denaturiztion at low temperatures. However, trying to explain stable nuclear isotopes to non-scientists once the word "nuclear" is uttered is impossible.
My house was built over 100 years ago. It is built with rip cut 2x4s. They are actually 2"x4". You would not want to have to carry them in your bare hands as the surface is full of splinters. Not like a smooth surface we can get today with carbide tipped blade. To get these rip cut boards smooth you would likely have to plane a considerable amount of wood off.There is little waste with modern saws and now that the 1.5"x3.5" nominal dimensions is standard, more boards can be cut from larger logs.
My first computer was a home built SWTPC 6800 with static RAM and audio cassette for storage. It was stolen along with my second computer that was a S-100 8088 system that had a hard drive. With a 10 MB maybe 20 MB hardrive, too long ago to remember.
I read the three volumes in college. I was a chemistry major, so this was all my own doing. I had built an eight bit computer in high school, a SWTPC 6800 machine. During college I became an assistant sysadmin on a DEC system- 10 minicomputer in one of the chemistry professor's lab. I still have to this day a deep interest in both chemistry and computers. These three volumes were the basis of my informal computer science education. (My formal education resulted in a Ph.D. in Physical Chemistry.) I was especially intrigued by the sorting algorithms and coded several of them in different languages for comparison of their operation.
The books are a fine examples of mathematical typography and I became an early adopter of Knuth's typography software TeX and Lamporte's LaTeX. I was the first person in the UIUC chemistry department to digitally typeset their dissertation and print it on the department's laser printer attached the the VAX-780. I investigated WEB (the self documenting language that TeX is written in) as a possibly useful programming tool, but found it to be much too cumbersome.
Others in this thread have commented on how miserly the algorithms are in their use of bits. The powerful processors and gigabytes of RAM available in desktop computers and even some portable devices can lead to bloated and sometimes inefficient programs. With the increasing tide of IoT devices with limited computational resource and available power, a miserly mindset can lead to more functional programs and better battery life. Even GPU programming lends itself to being miserly in the use of resources.
This set of books is not something to read to learn how to program. These are the volumes you read to become a craftsman and more than just competent at programming.
I had a Rubik's cube in the early 1980's and found that it was faster to pop it apart an reassemble it in the correct order. When a robot can do that, then I will be impressed..........
for neither man nor beast and beasts are no longer used. Coal mines in southern Ohio used dogs to pull carts out of the mines as they fit they height of the coal seam! Some hard rock mines had tunnels that were high enough for the mules to walk in them. They were worked underground until they could almost no longer see from the darkness and then moved back to the surface.
Many people have been killed in accidents and suffer from respiratory diseases from the dust in mines.
One of the highest levels of room temperature liquids, 55 M (moles/liter). A half liter of beer has on the order of 1.6e25 molecules of that dangerous stuff!
Exactly. Just like you don't need a seat belt to drive a car. The parameter space that can be easily probed is too small to say for certain that a gene is not needed.
Yes, the FAA has closed down model airplane clubs: Free State Aeromodelers Looks like it is not so free in the free state of Maryland. Their flight field is in Laurel, MD and was outside of the 15 nm no fly zone. Many other club fields are also inside of the new 30 nm radius. One can only hope that there are many retired lawyers who fly on these fields who will be willing to take on these new onerous regulations.
The term "maker" used to cause me to cringe as well, until I saw a plaque on a Pratt & Whitney gun boring lathe from the 1860's at the Harper's Ferry museum. The plaque read,
Pratt & Whitney
Makers
Hartford, Connecticut
If one of the earliest precision machinery manufactures thought of themselves as makers, maybe the term is not so bad after all.
I have been keeping bees as a hobby for eight years. Unfortunately, there are always winter losses. Sometimes even when the hive has plenty of food stored. The colony is likely to starve and freeze when there is brood to keep warm (the most important task for the worker bees in the winter) and the available stores is too far away for the number of bees in the over wintering colony. When this happens you will find many dead bees with there heads in the honeycomb cells trying to get any available honey and still stay warm in the ball of bees. It is very sad when you see this and honey is only a few centimeters away.
I had ten strong hives going into last winter and all ten cam through with strong populations, except one colony lost its queen. I had three nucleus hives (smaller hives) that I was trying to over winter for loss protection and two of the colonies dies as described above.
A fellow beekeeper who lives about two miles away and has been successfully keeping bees for several decades lost 3/4 of his colonies (of about 30) and had to buy packages to recover. No one can say why our experiences were so different.
I fed my colonies a great deal of sugar in the fall and early spring. I wanted the colonies to be strong going into winter, but then you run the risk of not enough food to support the large number of bees. Feeding sugar is much less expensive than buying package bees to rebuild and losing the honey crop for the spring. Eventhough I took measures to reduce the chance of the colonies swarming, most of them did.
Several years ago it seemed that the problems with the mites was starting to decrease. Newer strains like the Russian line of bees were more hygenic and would remove mites from their colonies. Some hobby beekeepers were trying to not treat for mites. However, it is now clear that the presence of the mites is only part of the problem and the diseases they transmit is not seen as the main threat. Therefore, treating for mites at least once a year is now firmly established and the USDA is suggesting the more frequent treatment may be necessary.
Beekeeping is applied biology. Every colony behaves differently and every year leads to different outcomes. I like physics and its reproducibility. I also like beekeeping because there are so many factors that affect the colonies and alway provide surprises.
We don't even have trains being run by computers yet and there is no driving involved, just acceleration and deceleration. Not only that, proper tailoring of acc/dec curves can save tremendous amounts of fuel. While successfully navigating a car in 2D or a plane in 3D may be much cooler than the mundane operation of a freight or passenger train, until we can have zero train accidents through the use of driverless trains, discussion of other forms of driverless transportation is premature.
A lot of the "folklore" that people believe is of very recent origin. My grandmother was in her thirties before the term "Ley Line" was thought of, and that was used to describe the sites of old road. The zinc=virility thing comes from the story of Cassanova (not the most reliable of info!) eating lots of oysters. Oysters are filter feeders and pick up a lot of heavy metals such as zinc in areas where mining and industry puts it in the water. Therfore, with a dab of fiction and a stroke of sympathetic magic, zinc=virility. Zinc is important for other reasons, but it comes in every green plant.
Actually, zinc is a very important heavy metal in all mutlicellular organisms and shellfish just happen to concentrate it a bit more than other organisms. They do not need mining effluent to concentrate zinc (ocean water already has enough) and it would probably be toxic to the oysters anyway since they are rather sensitive to water quality.
"Chemistry in Britain" had an article about ten years ago reviewing the realtionship between several folklore notions and zinc biochemistry. It turns out that when a man ejaculates, a significant amount of the total body zinc loading is lost. Therefore, eating foods rich in zinc more quickly restores zinc to the body. Another folklore tail is that masturbation causes acne. The connection discussed in the above mention article is that zinc is important for proper immune response and that a large loss of zinc may allow baterial infections that would not normally occur. The connection is obvious: repeated ejaculations results in zinc loss no matter how they come about. Whether eating zinc rich foods leads to greater virility is left to the reader.
To put this comment in context with the parent thread. I had a lab in my basement in junior high and high school I investigate first row transition metal coordination chemistry and metalurgy and the synthesis of esters (the compounds which give fruits their odors). When I was not working in my lab, I was learning electronics and eventually built a 6800 microcomputer. For you youngsters, building a computer in 1978 meant soldering sockets and parts onto pc boards. 8kB of memory and audio tape drive program storage, microcomputers have come a mighty long way in 20 years! Oh, and I have a Ph.D. in physical chemistry from the University of Illinois.
You might be interested in taking a look at
what StellarHost has to offer
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Finally, after playing in Verisign's voicemail jail for hours, I found someone who gave me the most candid response yet: ".us domains? Well, I wouldn't recommend those because they don't work very well. You should get a.com which we can help you with."
The only way to contact verisign via phone is to call right at 7:00am eastern. You will usually get a person right away. Kind of tough for those in California.
The final straw that pushed me kicking and screaming into getting a cell phone was the lack of functioning pay phones while I was trying to find a company in Northern Virginia. I eventually found one that worked (kind of), but the street noise was so loud, I could not hear the other party. When phone booths were removed, supposedly due to litigation, the usefulness of pay phones dropped dramatically. My wife and I got PCS phones the same week. Now that I have one, I am happy to
have it, but I still use the pay phone in the subway occasionally. I don't think that pay phones will every go away at sights of public transportation.
Over the centuries, the English have not allowed
the Scots to possess weapons, bag pipes, kilts, etc. as a means of oppression.
I keep a copy of the constitution in my desk. The
Second Amendment reads:
A well-regulated militia, being necessary to the
security of a free State, the right of the people
to keep and bear arms, shall not be infringed.
Notice that it says nothing about hunting. Much of the political noise about gun control focuses on the "need" of certain types of guns for hunting. The right to bear arms is to assure a free State. While an armed populace would be little threat to today's army, it still is a deterrent.
Many of the gun laws do little to keep guns out
of the hands of criminals. Stricter sentencing is needed for the use of guns in crime.
I believe that Jefferson said, "Anyone who
would give up freedom for safety deserves neither."
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My first paper in chemistry was submitted to the Journal of the American Chemical Society.
The review took over a year. This was before the internet and the editor dropped the ball. At that time,
it was bad form to ask the editor about the status of your submission as the process was already slow and
you did not want to pester the editor and get it treated more slowly.
Email has changed the whole process, but some journals are still slow.
Congratulations on the acceptance of your paper.
Machine learning does not even give a hint on causality.
It can glean properties from the training data, but does not even give a hint of what parts of the training data lead to the outcome.
Without causality, these data cannot be used to create new data points that have the desired outcome. It is more of a shotgun approach,
train on know data sets and then blast related data points to see of they may have properties related to the trained data sets. I have tried to make this generic,
but there are clear examples on the literature where the machine learning can identify properties of the data set better than many theories, but the resuolt can not be used to design new thing that have the desired properties.
Doesn't sound bad to me
https://www.youtube.com/watch?...
The execution of Lavoisier set the progress of chemistry back by decades.
Ego is inversely proportional to knowledge ~ Albert Einstein.
Some kind of preservative is needed.
Deuterium oxide could be use to preserve vaccines as it is by definition sterile and microbes
cannot grow in it without extensive adaptation. Additionally, D2O reduces protein denaturiztion at low temperatures.
However, trying to explain stable nuclear isotopes to non-scientists once the word "nuclear" is uttered is impossible.
An ice IX nano-environment!
My house was built over 100 years ago. It is built with rip cut 2x4s. They are actually 2"x4". You would not want to have to carry them in your bare hands as the surface is full of splinters. Not like a smooth surface we can get today with carbide tipped blade. To get these rip cut boards smooth you would likely have to plane a considerable amount of wood off.There is little waste with modern saws and now that the 1.5"x3.5" nominal dimensions is standard, more boards can be cut from larger logs.
My first computer was a home built SWTPC 6800 with static RAM and audio cassette for storage.
It was stolen along with my second computer that was a S-100 8088 system that had a hard drive.
With a 10 MB maybe 20 MB hardrive, too long ago to remember.
I read the three volumes in college. I was a chemistry major, so this was all my own doing. I had built an eight bit computer in high school, a SWTPC 6800 machine. During college I became an assistant sysadmin on a DEC system- 10 minicomputer in one of the chemistry professor's lab. I still have to this day a deep interest in both chemistry and computers. These three volumes were the basis of my informal computer science education. (My formal education resulted in a Ph.D. in Physical Chemistry.) I was especially intrigued by the sorting algorithms and coded several of them in different languages for comparison of their operation.
The books are a fine examples of mathematical typography and I became an early adopter of Knuth's typography software TeX and Lamporte's LaTeX. I was the first person in the UIUC chemistry department to digitally typeset their dissertation and print it on the department's laser printer attached the the VAX-780. I investigated WEB (the self documenting language that TeX is written in) as a possibly useful programming tool, but found it to be much too cumbersome.
Others in this thread have commented on how miserly the algorithms are in their use of bits. The powerful processors and gigabytes of RAM available in desktop computers and even some portable devices can lead to bloated and sometimes inefficient programs. With the increasing tide of IoT devices with limited computational resource and available power, a miserly mindset can lead to more functional programs and better battery life. Even GPU programming lends itself to being miserly in the use of resources.
This set of books is not something to read to learn how to program. These are the volumes you read to become a craftsman and more than just competent at programming.
I had a Rubik's cube in the early 1980's and found that it was faster to pop it apart an reassemble it in the correct order.
When a robot can do that, then I will be impressed..........
for neither man nor beast and beasts are no longer used.
Coal mines in southern Ohio used dogs to pull carts out of the mines as
they fit they height of the coal seam! Some hard rock mines had tunnels that
were high enough for the mules to walk in them. They were worked underground
until they could almost no longer see from the darkness and then moved back to the surface.
Many people have been killed in accidents and suffer from respiratory diseases from the dust in mines.
Automation is the way to go for mining.
One of the highest levels of room temperature liquids, 55 M (moles/liter).
A half liter of beer has on the order of 1.6e25 molecules of that dangerous stuff!
Exactly. Just like you don't need a seat belt to drive a car.
The parameter space that can be easily probed is too small to say for certain that a gene is not needed.
Yes, the FAA has closed down model airplane clubs:
Free State Aeromodelers
Looks like it is not so free in the free state of Maryland.
Their flight field is in Laurel, MD and was outside of the 15 nm no fly zone.
Many other club fields are also inside of the new 30 nm radius.
One can only hope that there are many retired lawyers who fly on these fields
who will be willing to take on these new onerous regulations.
The term "maker" used to cause me to cringe as well, until I saw a plaque on a Pratt & Whitney gun boring lathe from the 1860's at the Harper's Ferry museum.
The plaque read,
Pratt & Whitney
Makers
Hartford, Connecticut
If one of the earliest precision machinery manufactures thought of themselves as makers, maybe the term is not so bad after all.
I have been keeping bees as a hobby for eight years. Unfortunately, there are always winter losses. Sometimes even when the hive has plenty of food stored.
The colony is likely to starve and freeze when there is brood to keep warm (the most important task for the worker bees in the winter) and the available stores is too far away for the number of bees in the over wintering colony. When this happens you will find many dead bees with there heads in the honeycomb cells trying to get any available honey and still stay warm in the ball of bees. It is very sad when you see this and honey is only a few centimeters away.
I had ten strong hives going into last winter and all ten cam through with strong populations, except one colony lost its queen.
I had three nucleus hives (smaller hives) that I was trying to over winter for loss protection and two of the colonies dies as described above.
A fellow beekeeper who lives about two miles away and has been successfully keeping bees for several decades lost 3/4 of his colonies (of about 30) and had to buy packages to recover. No one can say why our experiences were so different.
I fed my colonies a great deal of sugar in the fall and early spring. I wanted the colonies to be strong going into winter, but then you run the risk of not enough food to support the large number of bees. Feeding sugar is much less expensive than buying package bees to rebuild and losing the honey crop for the spring.
Eventhough I took measures to reduce the chance of the colonies swarming, most of them did.
Several years ago it seemed that the problems with the mites was starting to decrease. Newer strains like the Russian line of bees were more hygenic and would remove mites from their colonies. Some hobby beekeepers were trying to not treat for mites. However, it is now clear that the presence of the mites is only part of the problem and the diseases they transmit is not seen as the main threat. Therefore, treating for mites at least once a year is now firmly established and the USDA is suggesting the more frequent treatment may be necessary.
Beekeeping is applied biology. Every colony behaves differently and every year leads to different outcomes.
I like physics and its reproducibility. I also like beekeeping because there are so many factors that affect the colonies and alway provide surprises.
That's too bad. A kilt is not a costume. I have worn my kilt to work, social functions, pubs, etc.
A man in a kilt is man and a half!
We don't even have trains being run by computers yet and there is no driving involved, just acceleration and deceleration. Not only that, proper tailoring of acc/dec curves can save tremendous amounts of fuel. While successfully navigating a car in 2D or a plane in 3D may be much cooler than the mundane operation of a freight or passenger train, until we can have zero train accidents through the use of driverless trains, discussion of other forms of driverless transportation is premature.
A lot of the "folklore" that people believe is of very recent origin. My grandmother was in her thirties before the term "Ley Line" was thought of, and that was used to describe the sites of old road. The zinc=virility thing comes from the story of Cassanova (not the most reliable of info!) eating lots of oysters. Oysters are filter feeders and pick up a lot of heavy metals such as zinc in areas where mining and industry puts it in the water. Therfore, with a dab of fiction and a stroke of sympathetic magic, zinc=virility. Zinc is important for other reasons, but it comes in every green plant.
Actually, zinc is a very important heavy metal in all mutlicellular organisms and shellfish just happen to concentrate it a bit more than other organisms. They do not need mining effluent to concentrate zinc (ocean water already has enough) and it would probably be toxic to the oysters anyway since they are rather sensitive to water quality.
"Chemistry in Britain" had an article about ten years ago reviewing the realtionship between several folklore notions and zinc biochemistry. It turns out that when a man ejaculates, a significant amount of the total body zinc loading is lost. Therefore, eating foods rich in zinc more quickly restores zinc to the body. Another folklore tail is that masturbation causes acne. The connection discussed in the above mention article is that zinc is important for proper immune response and that a large loss of zinc may allow baterial infections that would not normally occur. The connection is obvious: repeated ejaculations results in zinc loss no matter how they come about. Whether eating zinc rich foods leads to greater virility is left to the reader.
To put this comment in context with the parent thread. I had a lab in my basement in junior high and high school I investigate first row transition metal coordination chemistry and metalurgy and the synthesis of esters (the compounds which give fruits their odors). When I was not working in my lab, I was learning electronics and eventually built a 6800 microcomputer. For you youngsters, building a computer in 1978 meant soldering sockets and parts onto pc boards. 8kB of memory and audio tape drive program storage, microcomputers have come a mighty long way in 20 years! Oh, and I have a Ph.D. in physical chemistry from the University of Illinois.
You might be interested in taking a look at what StellarHost has to offer
http://www.stellarhost.com
We have a rock solid network and great customer support.
Finally, after playing in Verisign's voicemail jail for hours, I found someone who gave me the most candid response yet: ".us domains? Well, I wouldn't recommend those because they don't work very well. You should get a .com which we can help you with."
The only way to contact verisign via phone is to call right at 7:00am eastern. You will usually get a person right away. Kind of tough for those in California.
The final straw that pushed me kicking and screaming into getting a cell phone was the lack of functioning pay phones while I was trying to find a company in Northern Virginia. I eventually found one that worked (kind of), but the street noise was so loud, I could not hear the other party. When phone booths were removed, supposedly due to litigation, the usefulness of pay phones dropped dramatically. My wife and I got PCS phones the same week. Now that I have one, I am happy to have it, but I still use the pay phone in the subway occasionally. I don't think that pay phones will every go away at sights of public transportation.
Over the centuries, the English have not allowed the Scots to possess weapons, bag pipes, kilts, etc. as a means of oppression.
I keep a copy of the constitution in my desk. The Second Amendment reads:
A well-regulated militia, being necessary to the security of a free State, the right of the people to keep and bear arms, shall not be infringed.
Notice that it says nothing about hunting. Much of the political noise about gun control focuses on the "need" of certain types of guns for hunting. The right to bear arms is to assure a free State. While an armed populace would be little threat to today's army, it still is a deterrent.
Many of the gun laws do little to keep guns out of the hands of criminals. Stricter sentencing is needed for the use of guns in crime.
I believe that Jefferson said, "Anyone who would give up freedom for safety deserves neither."
Jeff Forbes
Editor, Clan Forbes Newsletter
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