I've been using this built-in support in both browsers for years...
POP Goes the GMail and others
on
Gmail in the News
·
· Score: 2, Interesting
Has anyone actually tried the utilities listed in the original post? The lack of import and export options from gmail is a real limiting factor (I already have a lot of mail I'd like to search). What happens if/when google goes under? How do we extract our gigabyte? These utilities look very promising, but slashdotter stress-testing seems in order...
But p53 is also invovled in DNA repair and checkpointing during the cell cycle. Without it, mutations accumulate much faster. Targeting the Ras pathway is fine, but there are multiple pathways that will drive the cell cycle (or alternatively, lack of apoptosis will also allow the cells to proliferate), and many genes on the pathways can have mutations.
The part of the reovirus treatment that's effective is that mutations in the ras pathway occur in a third of tumor types, most notably large percentages of pancreatic, lung, sporadic colorectal, and myleoid leukemia cancers. If you look at the numbers these four types account for more than half the expected cancer deaths in the united states for 2003.
Granted, the actual number of cases the treatment will be effective against is less than that, but it's far more effective that chemo, and infinitely less damaging to the patient. I would say targeting the ras pathway is a little better than "fine."
Wow, that's a totally ignorant statement. I'm not even going to get into how you think cancer can evolve.. it's just not possible. Read some of the other posts.
As for treatment, almost all cancer research right now (especially that use viruses) attempt to target the very nature of cancer: uncontrolled cell growth. There are some very key protein pathways (conserved through almost every species we've bothered to look for them in) that are very related to this growth regulation. For example, p53 is a big one that actively prevents uncontrolled cell growth (so many cancers somehow mess up the creation of this protein, thereby increasing the propensity for uncontrolled cell growth). Another big one is the ras pathway, which is responsible for telling the cell when it should grow normally. If this pathway gets sped up or damaged, then you get uncontrolled cell growth.
The thrust of many cancer therapies right now is to use these properties to our advantage. The reovirus (previously covered), for example, is only able to infect cells with a messed up ras pathway (which only happens in tumor cells) so it will always be an effective treatment against cancer, unless the definition of cancer changes.
Actually, since viruses have been investigated for use in cancer therapy for many years now, there are a bunch of methods.. the most efficient procedure I read about (just wrote a research paper on this) works by injecting immunosuppresive drugs (like cyclosporine) along with the virus into the tumor. It keeps everything very contained and prevents the immune system from destroying the virus long enough for the virus to destroy the tumor.
There's plenty of published stuff about this.. research in Adenovirus cancer therapy has been going on since the mid-80's. Scientific American recently published a nice article summarizing adenovirus vs. tumor research that very clearly demonstrates how a treatment might work.
This presents a really interesting concept.. if the surface of the keyboard could change based on whatever activity you happened to be doing. For typing and other "normal" tasks it could display a standard keyboard, but for the "finger painting" suggestion above the "hotspots" of the keyboard could change to a color palette and brush sizes. Or games could have specific interfaces tailored to that game. The possibilities are endless.
Slashdot Mirror
And aren't those people already viewing the page on slashdot? Hosting it here at the source of the traffic makes a lot of sense.
http://archives.cnn.com/2000/HEALTH/11/15/monkey.b rain/index.html
What's the motivation for only charging .net? Why that one (first) ?
You could actually do this in IE as well by merging the values below into the registry:
e arch?q=%s&btnG=Google+S earch"
[HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\SearchUrl]
"provider"=""
[HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\SearchUrl\g]
@="http://www.google.com/s
" "="+"
"#"="%23"
"&"="%26"
"?"="%3F"
"+"="%2B"
"="="%3D"
I've been using this built-in support in both browsers for years...
Has anyone actually tried the utilities listed in the original post? The lack of import and export options from gmail is a real limiting factor (I already have a lot of mail I'd like to search). What happens if/when google goes under? How do we extract our gigabyte? These utilities look very promising, but slashdotter stress-testing seems in order...
The part of the reovirus treatment that's effective is that mutations in the ras pathway occur in a third of tumor types, most notably large percentages of pancreatic, lung, sporadic colorectal, and myleoid leukemia cancers. If you look at the numbers these four types account for more than half the expected cancer deaths in the united states for 2003.
Granted, the actual number of cases the treatment will be effective against is less than that, but it's far more effective that chemo, and infinitely less damaging to the patient. I would say targeting the ras pathway is a little better than "fine."
As for treatment, almost all cancer research right now (especially that use viruses) attempt to target the very nature of cancer: uncontrolled cell growth. There are some very key protein pathways (conserved through almost every species we've bothered to look for them in) that are very related to this growth regulation. For example, p53 is a big one that actively prevents uncontrolled cell growth (so many cancers somehow mess up the creation of this protein, thereby increasing the propensity for uncontrolled cell growth). Another big one is the ras pathway, which is responsible for telling the cell when it should grow normally. If this pathway gets sped up or damaged, then you get uncontrolled cell growth.
The thrust of many cancer therapies right now is to use these properties to our advantage. The reovirus (previously covered), for example, is only able to infect cells with a messed up ras pathway (which only happens in tumor cells) so it will always be an effective treatment against cancer, unless the definition of cancer changes.
Actually, since viruses have been investigated for use in cancer therapy for many years now, there are a bunch of methods.. the most efficient procedure I read about (just wrote a research paper on this) works by injecting immunosuppresive drugs (like cyclosporine) along with the virus into the tumor. It keeps everything very contained and prevents the immune system from destroying the virus long enough for the virus to destroy the tumor.
There's plenty of published stuff about this.. research in Adenovirus cancer therapy has been going on since the mid-80's. Scientific American recently published a nice article summarizing adenovirus vs. tumor research that very clearly demonstrates how a treatment might work.
Anyone know anything about the remote assistance clone they seem to include? Does that mean they've also got a working Remote Desktop Server?
This presents a really interesting concept.. if the surface of the keyboard could change based on whatever activity you happened to be doing. For typing and other "normal" tasks it could display a standard keyboard, but for the "finger painting" suggestion above the "hotspots" of the keyboard could change to a color palette and brush sizes. Or games could have specific interfaces tailored to that game. The possibilities are endless.