Since Martin Michael Lomasney (December 3, 1859 -August 12, 1933) was a Massachusetts politician, fuck him and everything he ever said or wrote, including the drivel you quoted.
I do NOT like politicians, I would not take their advice. EVER. Why not just quote Charles Manson? He's almost as bad as a politician.
The Lomasney quote is usually taken as an indictment of the behavior of machine bosses and their corrupt behavior. Your interpretation of it as an attempt at sound advice is novel.
...what CmdrTaco missed was exactly what Apple saw. There was a massive untapped market for user-friendly consumer electronic & computing products. While the smug technoratti were still obsessed with stats & features, Apple saw what people wanted before they did and gave it to them. CmdrTaco's "No wireless, less space than a Nomad. Lame." will go down in history (like "Let them eat cake") as emblematic of a group of 'elites' detached from reality.
BTW: In case you haven't noticed, Apple tapped that market and now they have a $500B market cap.
Which is why he is now working at a desperate old media low budget boiler room instead of in a plush corner office.
They're coming up with ever-more creative ways to hurt peaceful protesters -- and let's be honest: Most of the time, they provoke, prod, cajoule, and taunt these people until one of them out of the dozen, hundred, or thousand there snaps, then they point and say "See! See! We're justified" and open up unholy horror on everyone nearby
"one of them" = police plant in the crowd, you mean
The German Wehrmacht (and the other regular branches of the German military in WWII) had little to do with the Nazi party. The only "Nazi" military was the Waffen-SS, whose notable accomplishments include running death camps and overall pathetic performance in actual combat. The American stereotype of branding anything related to Germany in the 1933-1945 era as "Nazi" is just wrong.
I know, right? I mean, when we got there we couldn't find a single person who was a Nazi.
Comedy aside, it does present a good point: in the future they might think about attaching 1, maybe 2 limbs at a time so the support systems can catch up.
I would think that two legs which are from the same donor would be preferred. Arms are probably not as necessary to match.
a seminar on drug development by someone in management in of one of the major companies.
There is your problem in a nutshell.
You keep talking about "better understanding" as if it were an alien concept. Maybe it is to that managment dweeb. When you do get your doctorate and go for interviews, you will see whole buildings of people searching for that better understanding.
the current drug development systems are horribly inefficient , they resemble what programmers would conceder "brute force" methods, try almost everything you can see what has an effect and go from there. At each step were you might want to improve the drug only use understanding based approaches only if all else fails. This used to work much better, the diseases that we where trying to treat where simpler and our understanding worse, but as modern technology advances this methodology becomes more wastefull. Part of the problem is that understanding how a drug works gives your rivals a way of making alternatives so is unattractive unless you have no other option, but there is a lot of inertia involved as well. This is not their only problem but it is a massive issue and they should be able to save a lot of time and money by starting from understanding instead.
Human biology is a lot more complex than a computer, and failure of a drug in that system is somewhat less socially and legally tolerated than a computer crashing. Perhaps you, Dr. AC, with your apparent singular knowledge of the problem, could enlighten the thousands of pharmaceutical researchers as to what - exactly - they are doing wrong? I am sure they are ready to drop their Erlenmeyer flasks and instead just "understand".
"Or, you can sell it cheap if the people who forked over the original $200M didn't care to make a profit."
GlaxoSmithKline Pharmaceuticals makes over $8 billion dollars a year on 1 drug alone... Advair.
It's $450 for a 30day supply.
Their patent has run out, but they either sue or bribe the FDA into scuttling any efforts of anyone that attempts to make a generic.
Of course, there's a generic in India that sells for $30/month
I literally can not breath without taking this.
So, I agree... they should make a profit. I don't even want the drug to be "cheap"
But is $8 billion a year enough profit? Would it hurt them if it were only... I dunno... 2 Billion?
And I don't want it for free... but $450? Really? Could be do it for $100? I don't need the fancy box it comes in... or to hear all those ads... the dispenser is right out of startrek. Dumb it down a bit. I just want to be able to afford to breath again.
You're already Rich as fuck GlaxoSmithKline. You've got swimming pools full of money. Please... price your drug back down out of the "Holy fucking shit" range so I can breath again... or at least let someone else do it for you.
Have you been in a Walmart? People already equate them with large scale human suffering.
Yeah - how do you think that yellow disc is able to fly around the store knocking prices down unless the jackboot of a supervisor in some Chinese sweatshop is being pushed progressively harder onto the neck of the working comrades?
Slashdot Mirror
How much will this cost per patient? Who is going to pay?
1. Cover Yaris with LEDs.
2. Project image of Maserati on LEDs.
3. Pick up chicks.
Since Martin Michael Lomasney (December 3, 1859 -August 12, 1933) was a Massachusetts politician, fuck him and everything he ever said or wrote, including the drivel you quoted.
I do NOT like politicians, I would not take their advice. EVER. Why not just quote Charles Manson? He's almost as bad as a politician.
The Lomasney quote is usually taken as an indictment of the behavior of machine bosses and their corrupt behavior. Your interpretation of it as an attempt at sound advice is novel.
...what CmdrTaco missed was exactly what Apple saw. There was a massive untapped market for user-friendly consumer electronic & computing products. While the smug technoratti were still obsessed with stats & features, Apple saw what people wanted before they did and gave it to them. CmdrTaco's "No wireless, less space than a Nomad. Lame." will go down in history (like "Let them eat cake") as emblematic of a group of 'elites' detached from reality.
BTW: In case you haven't noticed, Apple tapped that market and now they have a $500B market cap.
Which is why he is now working at a desperate old media low budget boiler room instead of in a plush corner office.
Perhaps he had a prior arrangement with Google's competitor to develop distrust, in exchange for a well-paid sinecure once he was done.
"Never write if you can speak; never speak if you can nod; never nod if you can wink." - Martin Lomasney
They're coming up with ever-more creative ways to hurt peaceful protesters -- and let's be honest: Most of the time, they provoke, prod, cajoule, and taunt these people until one of them out of the dozen, hundred, or thousand there snaps, then they point and say "See! See! We're justified" and open up unholy horror on everyone nearby
"one of them" = police plant in the crowd, you mean
In the U.S, peaceful protester who abide by the law will have no problem with this!
You just have to know your rights. http://www.youtube.com/watch?v=nPeWSpB_7w4
The German Wehrmacht (and the other regular branches of the German military in WWII) had little to do with the Nazi party. The only "Nazi" military was the Waffen-SS, whose notable accomplishments include running death camps and overall pathetic performance in actual combat. The American stereotype of branding anything related to Germany in the 1933-1945 era as "Nazi" is just wrong.
I know, right? I mean, when we got there we couldn't find a single person who was a Nazi.
We need to find out why matter is called matter and antimatter is called antimatter and not the other way around.
Hold on a tick - the Patent Office rejected a claim? The United States Patent Office? Are you sure about that?
Comedy aside, it does present a good point: in the future they might think about attaching 1, maybe 2 limbs at a time so the support systems can catch up.
I would think that two legs which are from the same donor would be preferred. Arms are probably not as necessary to match.
They are using the Apple logos....
That's not an apple - it is an Asian pear. Completely different.
That is not how one fries a motherboard.
And tons here: http://www.nature.com/nnano/journal/vaop/ncurrent/full/nnano.2012.20.html
And here is the structure they are imaging: http://en.wikipedia.org/wiki/Naphthalocyanine
The purpose of an IT department is to provide a service to the organization, not to make the organization bend over to the IT dept.
Thousands of corporate ITers just spit coffee onto their monitors.
Here is an Apple commercial that claims that Macintoshes don't get viruses.
Flashback Trojan. Not a virus.
I read to find out what happens next, not to control it.
a seminar on drug development by someone in management in of one of the major companies.
There is your problem in a nutshell.
You keep talking about "better understanding" as if it were an alien concept. Maybe it is to that managment dweeb. When you do get your doctorate and go for interviews, you will see whole buildings of people searching for that better understanding.
the current drug development systems are horribly inefficient , they resemble what programmers would conceder "brute force" methods, try almost everything you can see what has an effect and go from there. At each step were you might want to improve the drug only use understanding based approaches only if all else fails. This used to work much better, the diseases that we where trying to treat where simpler and our understanding worse, but as modern technology advances this methodology becomes more wastefull. Part of the problem is that understanding how a drug works gives your rivals a way of making alternatives so is unattractive unless you have no other option, but there is a lot of inertia involved as well. This is not their only problem but it is a massive issue and they should be able to save a lot of time and money by starting from understanding instead.
Human biology is a lot more complex than a computer, and failure of a drug in that system is somewhat less socially and legally tolerated than a computer crashing. Perhaps you, Dr. AC, with your apparent singular knowledge of the problem, could enlighten the thousands of pharmaceutical researchers as to what - exactly - they are doing wrong? I am sure they are ready to drop their Erlenmeyer flasks and instead just "understand".
"Or, you can sell it cheap if the people who forked over the original $200M didn't care to make a profit." GlaxoSmithKline Pharmaceuticals makes over $8 billion dollars a year on 1 drug alone... Advair. It's $450 for a 30day supply. Their patent has run out, but they either sue or bribe the FDA into scuttling any efforts of anyone that attempts to make a generic. Of course, there's a generic in India that sells for $30/month I literally can not breath without taking this. So, I agree... they should make a profit. I don't even want the drug to be "cheap" But is $8 billion a year enough profit? Would it hurt them if it were only... I dunno... 2 Billion? And I don't want it for free... but $450? Really? Could be do it for $100? I don't need the fancy box it comes in... or to hear all those ads... the dispenser is right out of startrek. Dumb it down a bit. I just want to be able to afford to breath again. You're already Rich as fuck GlaxoSmithKline. You've got swimming pools full of money. Please... price your drug back down out of the "Holy fucking shit" range so I can breath again... or at least let someone else do it for you.
It costs billions to get a drug to market: http://pipeline.corante.com/archives/2012/02/10/the_terrifying_cost_of_a_new_drug.php
iAgree
eSright
...New Testament is...basically a branch of history....
For certain values of 'history'.
I think I will quietly document this potentially incriminating meeting by WHIPPING OUT A GRENADE AND SLAMMING IT ON THE CONFERENCE TABLE.
Actually, I think their point was that they had or were developing a similar package which would use a smartphone instead of a grenade.
And if women didn't walk around dressed like sluts, they wouldn't get raped.
That's true, but how does this relate to the conversation?
There were women there walking around dressed like pigeons.
Have you been in a Walmart? People already equate them with large scale human suffering.
Yeah - how do you think that yellow disc is able to fly around the store knocking prices down unless the jackboot of a supervisor in some Chinese sweatshop is being pushed progressively harder onto the neck of the working comrades?