But they do have them.
The real problem in hemophilia is with clotting factors, associated proteins that bind the platelets together and stick them in place, rather than a lack of platelets.
Actually, the simple process of removing blood from the body is not mutagenic - for example, think of blood transfusions, where blood is not only removed from the body, but frozen and stored.
Also, the large percentage of blood consisting of the red blood cells and platelets don't actually have any DNA in them to be mutated - these cells don't have nuclei.
Finally, in bone marrow transplants, one method of collecting the marrow cells to transplant is to hook the donor up to a machine through which their blood flows. In the machine, the stem cells (the cells that divide to produce all the elements of blood, including red blood cells and immune cells) are separated out, and these are the cells that are then transferred as the marrow transplant. You can find out more about this process here.
The objective with this treatment is to cure the cancer - so if simply removing the cells from the body causes cancer, it would be a very counter-productive treatment.
I wonder how he rationalized his sudden decision to quit for fear of typecasting with his decision to contact the producer and ask for the role, as described in this BBC article and another featured on slashdot a couple weeks ago.
I can't tell from the articles if he'll only be in the one episode, or if they've already shot more episodes from this season. But asking for a role and suddenly discovering that you're too good for it - that's frustrating from the perspective of all the folks out there who would love to play an iconic character like the Doctor.
The valid comparison isn't so much IMDB as it is Rotten Tomatoes, which also compiles reviews for movies. However, with the google version, you don't even have to know the name of the movie:
"val kilmer popcorn" brings up Real Genius
"mike and the bots" brings up MST3k - as the second hit (apparently The Phantom was crying out to be MSTed)
Of course, Rotten Tomatoes picks an exemplary or pithy line from the review to quote, whereas google simply takes the first line of the review, or the line containing your search term. The convenience of having it built into google is seductive, though.
I've thought about the same issue many times, and I think there's a couple of points that might be worth making.
The use of medical technology to sustain those who might otherwise die and not pass on their genes isn't some kind of anti-evolution, where we make the population into a bunch of weak slobs who cannot survive, their bodies riddled with diseases. We're simply stopping, piece by piece, the natural selection that eliminates those with unfavorable combinations of genes. However, in many cases, those genes would still be present in the gene pool even if we were undergoing natural selection. The genes in question are recessive, and sometimes there can come some benefit to the species in the long run for those who have one copy each of the "normal" and "abnormal" genes. A great example of this is sickle cell anemia: the prevalence of SCA increases in areas where malaria is endemic, because to be a carrier of SCA protects you somewhat against the disease, even though to have two recessive sickle cell genes means you will die early. (Natural selection at work in our world)
So if we were to, say, eliminate the disease malaria, perhaps - or find a way to save sickle cell patients who would otherwise die young, what would happen. Well, we know that the sickle cell gene would not disappear completely - look at populations for whom malaria is not a problem. The gene still exists, preserving the genetic diversity that allows our species to respond to the demands of natural selection, if and when they impose themselves.
So to allow humans with diseases that would have killed them before reproducing to reproduce - even then it does not necessarily mean that their children will have that condition. For one thing, a number of these conditions render the bearer infertile. For another, it takes two parents to make a child. Perhaps we would see an increase in negative genes in the general population - but the prevalence of these genes is not high in the first place, and to require medical care to live is also not the most attractive lure to a potential mate.
All of this does not take into account other aspects of life, such as whether we should strive to save the children of rich people (who we will then care for probably the rest of their lives) when we can help many poorer folk with simpler medical conditions. Honestly, I don't think I would have made the choice these parents did - but not because I'm sure it will spell the doom of our species. I'm confident that if and when our civilization crumbles and we are cast into the dark ages, natural selection will assert itself, and our gene pool will respond accordingly. But until then, perhaps continuing to save those who would otherwise not is only going to give them lives they might otherwise never have had.
ps: I can't tell from the details in the article, but many babies born with defects have those defects from developmental abnormalities, rather than genetic conditions - thus saving them doesn't change the gene pool.
The one area in which MS Ofiice is way ahead of any open source software is the functionality of Excel. Making graphs, sorting and binning, analyzing data - these are basic but exceedingly useful functions Excel does much better than any open source spreadsheet software I've ever used. Those who rely heavily on data analysis will use higher-powered programs than Excel, but for intermediate users, having that functionality quickly at hand is very useful. This is one area where, though it's not a fancy "new innovation," that could really improve the usefulness of open source spreadsheet programs.
The vagus nerve is the a major carrier of parasympathetic nerve fibers. The parasympathetic nerves, when stimulated, mediate the "resting" states of the body - increasing digestion, slowing heart rate, constricting the airways, and so on. In vagal nerve stimulation, the side effects you see don't affect the heart, they are more likely to affect the airways (you can experience hoarseness and difficulty breathing) this is probably because the parasympathetic nerve activation is very specific - you activate one fiber, which has a very specific effect, rather than activating the whole parasympathetic nervous system.
The point is, this is approved because it is safe - it doesn't damage the heart, though I'm sure it's possible that some side effects could include those on heart rate. And "sending shocks into nerves" - this is how the body sends signals on nerves! Sending excess current in would be a bad idea, yes, but electricity itself is not evil. Similarly, it seems that limited electrical signals in the brain could have benefits that outweigh the negatives.
ps: I have no idea WHY vagal stimulation works, though.
Ghosts use every means possible to get the users attention and affection but their modus operandi varies in accordance with the preferred segment of users they try to reach. Some rely mostly on entertainment e.g. by becoming popular as respected opponents in the local computer game, other use the assistive interaction as their preferred metier. Some perform practical jokes, some are 'jack-ass'ing', others rely on more innocent ways of entertainment (like the singing sisters street performing at second floor) while a few are responsible polite and earn their ITU's[positive feedback] from maximizing the standard of their services.
Yeah, I would agree. The HardOCP article includes lines like:
We liken investors giving Mr. Roberts money to people playing dice in Vegas. You just have to roll enough times and sooner or later you'll get a winner. Obviously, this isn't a solid winning strategy in Vegas or the business world.
and reading the letter, Infinium had a couple of valid corrections that HardOCP refused to take (if true, yadda yadda) - this is the funniest line from the letter, though:
By the way, you later told Kevin Bachus of Infinium that you declined any follow ups because - you believed that you were being invited to visit Florida only so Mr. Roberts could physically attack you.
That war is important to movie studios, which last week saw the escape in Los Angeles of a film pirate. Johnny Ray Gasca is accused of using a camcorder to illegally record and distribute prerelease movie screenings. Gasca made off days before his trial was to begin, while in the custody of his lawyer. He remains a fugitive.
He is considered armed and dangerous, bearing several semi-automatic, uh, video cameras. But don't worry, folks - the trusty FBI is hard at work hunting him down so that small children can sleep soundly at night.
The full quote is:
"The problem is not a lack of highly educated workers," said Scott Kirwin, founder of the Information Technology Professionals Association of America. "The problem is a lack of highly educated workers willing to work for the minimum wage or lower in the U.S.
This is not Carly speaking. Carly tried to make the point that HP wants better training for Americans, the implication being that Americans aren't trained well enough. (thus all the talk about funding for physical sciences, etc.)
Scott Kirwin is saying that that's false, that the problem is not that American workers aren't poorly trained, they just want higher wages than foreign workers.
The point that Jefferson is trying to get across is not that patents should be outlawed (his group's idea is that end products can be sold, but that tools should be shared) or that big biotech companies should not succeed, but rather that the ultimate goal of those companies is to make money for themselves. Large profits do not lie in creating useful technologies for developing countries, they lie in creating wonder drugs for the rich fraction of the world.
This is no different from the technologies applied to American crops, it's just that the idea is to make it easier for poor countries and their citizens to help solve their own problems. Seems to me that this wouldn't affect big business all that much, and it could give a real boost to the places and people that really need it.
And really, the evil terrorists who want to develop the WMD - are they going to sit around saying "well, if only we weren't limited by those dratted patent laws?" No. This idea is pretty much designed to help those who need it - the evildoers don't really need any help.
Hey! They're not the first - I made an internet video and plastered it to the internet for money long ago! Just like them, we thought out every aspect of filmmaking afresh and casted before writing the story!
what, porn doesn't count?...
Presumably noone who already uses linux is going to shell out for a more expensive box by a major manufacturer - and for the inexperienced user considering the switch to Linux, the fact that the computer is not supported and the software is uninstalled is going to strongly reduce the chances that they're going to buy it either.
It's a shame, because it seems that the main benefit of a company like HP offering this machine would be to help increase the OS market share of Linux. If it doesn't do well because it doesn't appeal to new buyers, will the corporation (and competitors?) decide that this is a failed experiment and leave the linux market to people like wal-mart?
Maybe corporations that hire their own tech support would go for this - be more likely with pre-installation, though.
yeast culture, eat it once (warning: various antibiotics will kill them, so you'll have to make a "refill")
Actually, antibiotics kill bacteria, not yeast. There's a balance within the body of microorganisms, including bacteria and yeast, that keep each other's growth in check.
So what you could see while taking antibiotics would be a possible overgrowth of yeast within the body. Not so much fun.
This is a fantastic development, though, and a huge step ahead for new medical therapies.
Slashdot Mirror
But they do have them. The real problem in hemophilia is with clotting factors, associated proteins that bind the platelets together and stick them in place, rather than a lack of platelets.
Also, the large percentage of blood consisting of the red blood cells and platelets don't actually have any DNA in them to be mutated - these cells don't have nuclei.
Finally, in bone marrow transplants, one method of collecting the marrow cells to transplant is to hook the donor up to a machine through which their blood flows. In the machine, the stem cells (the cells that divide to produce all the elements of blood, including red blood cells and immune cells) are separated out, and these are the cells that are then transferred as the marrow transplant. You can find out more about this process here. The objective with this treatment is to cure the cancer - so if simply removing the cells from the body causes cancer, it would be a very counter-productive treatment.
I can't tell from the articles if he'll only be in the one episode, or if they've already shot more episodes from this season. But asking for a role and suddenly discovering that you're too good for it - that's frustrating from the perspective of all the folks out there who would love to play an iconic character like the Doctor.
"val kilmer popcorn" brings up Real Genius
"mike and the bots" brings up MST3k - as the second hit (apparently The Phantom was crying out to be MSTed)
Of course, Rotten Tomatoes picks an exemplary or pithy line from the review to quote, whereas google simply takes the first line of the review, or the line containing your search term. The convenience of having it built into google is seductive, though.
An interesting contrast:
coming in at #40: What's Happening to my Body? Book for Girls: A Growing-Up Guide for Parents & Daughters by Lynda Madaras
and at #61: What's Happening to my Body? Book for Boys: A Growing-Up Guide for Parents & Sons by Lynda Madaras
Clearly, it's better for boys to learn about their bodies. I wonder what the rationale was for libraries that chose to ban one book and not the other.
The use of medical technology to sustain those who might otherwise die and not pass on their genes isn't some kind of anti-evolution, where we make the population into a bunch of weak slobs who cannot survive, their bodies riddled with diseases. We're simply stopping, piece by piece, the natural selection that eliminates those with unfavorable combinations of genes. However, in many cases, those genes would still be present in the gene pool even if we were undergoing natural selection. The genes in question are recessive, and sometimes there can come some benefit to the species in the long run for those who have one copy each of the "normal" and "abnormal" genes. A great example of this is sickle cell anemia: the prevalence of SCA increases in areas where malaria is endemic, because to be a carrier of SCA protects you somewhat against the disease, even though to have two recessive sickle cell genes means you will die early. (Natural selection at work in our world)
So if we were to, say, eliminate the disease malaria, perhaps - or find a way to save sickle cell patients who would otherwise die young, what would happen. Well, we know that the sickle cell gene would not disappear completely - look at populations for whom malaria is not a problem. The gene still exists, preserving the genetic diversity that allows our species to respond to the demands of natural selection, if and when they impose themselves.
So to allow humans with diseases that would have killed them before reproducing to reproduce - even then it does not necessarily mean that their children will have that condition. For one thing, a number of these conditions render the bearer infertile. For another, it takes two parents to make a child. Perhaps we would see an increase in negative genes in the general population - but the prevalence of these genes is not high in the first place, and to require medical care to live is also not the most attractive lure to a potential mate.
All of this does not take into account other aspects of life, such as whether we should strive to save the children of rich people (who we will then care for probably the rest of their lives) when we can help many poorer folk with simpler medical conditions. Honestly, I don't think I would have made the choice these parents did - but not because I'm sure it will spell the doom of our species. I'm confident that if and when our civilization crumbles and we are cast into the dark ages, natural selection will assert itself, and our gene pool will respond accordingly. But until then, perhaps continuing to save those who would otherwise not is only going to give them lives they might otherwise never have had.
ps: I can't tell from the details in the article, but many babies born with defects have those defects from developmental abnormalities, rather than genetic conditions - thus saving them doesn't change the gene pool.
You might run into at least one other problem while trying to use Verizon's service with your Powerbook. Maybe they'll update this soon?
The one area in which MS Ofiice is way ahead of any open source software is the functionality of Excel. Making graphs, sorting and binning, analyzing data - these are basic but exceedingly useful functions Excel does much better than any open source spreadsheet software I've ever used. Those who rely heavily on data analysis will use higher-powered programs than Excel, but for intermediate users, having that functionality quickly at hand is very useful. This is one area where, though it's not a fancy "new innovation," that could really improve the usefulness of open source spreadsheet programs.
The point is, this is approved because it is safe - it doesn't damage the heart, though I'm sure it's possible that some side effects could include those on heart rate. And "sending shocks into nerves" - this is how the body sends signals on nerves! Sending excess current in would be a bad idea, yes, but electricity itself is not evil. Similarly, it seems that limited electrical signals in the brain could have benefits that outweigh the negatives.
ps: I have no idea WHY vagal stimulation works, though.
I bet the freshmen are easy targets...
We liken investors giving Mr. Roberts money to people playing dice in Vegas. You just have to roll enough times and sooner or later you'll get a winner. Obviously, this isn't a solid winning strategy in Vegas or the business world.
and reading the letter, Infinium had a couple of valid corrections that HardOCP refused to take (if true, yadda yadda) - this is the funniest line from the letter, though:
By the way, you later told Kevin Bachus of Infinium that you declined any follow ups because - you believed that you were being invited to visit Florida only so Mr. Roberts could physically attack you.
He is considered armed and dangerous, bearing several semi-automatic, uh, video cameras. But don't worry, folks - the trusty FBI is hard at work hunting him down so that small children can sleep soundly at night.
This is not Carly speaking. Carly tried to make the point that HP wants better training for Americans, the implication being that Americans aren't trained well enough. (thus all the talk about funding for physical sciences, etc.)
Scott Kirwin is saying that that's false, that the problem is not that American workers aren't poorly trained, they just want higher wages than foreign workers.
Unclear article writing.
This is no different from the technologies applied to American crops, it's just that the idea is to make it easier for poor countries and their citizens to help solve their own problems. Seems to me that this wouldn't affect big business all that much, and it could give a real boost to the places and people that really need it.
And really, the evil terrorists who want to develop the WMD - are they going to sit around saying "well, if only we weren't limited by those dratted patent laws?" No. This idea is pretty much designed to help those who need it - the evildoers don't really need any help.
Hey! They're not the first - I made an internet video and plastered it to the internet for money long ago! Just like them, we thought out every aspect of filmmaking afresh and casted before writing the story! what, porn doesn't count? ...
It's a shame, because it seems that the main benefit of a company like HP offering this machine would be to help increase the OS market share of Linux. If it doesn't do well because it doesn't appeal to new buyers, will the corporation (and competitors?) decide that this is a failed experiment and leave the linux market to people like wal-mart?
Maybe corporations that hire their own tech support would go for this - be more likely with pre-installation, though.
Actually, antibiotics kill bacteria, not yeast. There's a balance within the body of microorganisms, including bacteria and yeast, that keep each other's growth in check.
So what you could see while taking antibiotics would be a possible overgrowth of yeast within the body. Not so much fun.
This is a fantastic development, though, and a huge step ahead for new medical therapies.