Additionally there are other mechanisms. Take a dozen peaches, peel them and put them in a baggie in the freezer. Thaw them out a week later. Notice they're al brown? Now do the same thing but add vitamin C to them as anybody would who followed the recipe in the book. Now notice when you thaw them out they're the original color. That haven't oxidized.
The same thing happens in animal bodies, so it's not always the matter of supplying an essential molecule hoping a reaction will take place, sometimes you can just flood the system and the mere physical presence of that much of the molecule does useful things - Pauling showed with clinical trials (available online at the Pauling institute) that C alone in large doses will kill many viruses, and specifically Polio.
C is also about the best line of defence against insect and even snake bites.
Of course as a natural (as in, it's in the body anyway) medicine, the body which knows what to do with the molecule so there's no side effects unlike synthetic medicines which all have side effects and along with botched surgery make modern medicine the third leading cause of death in the United States today. The thing is, you can patent synthetic medicine; the IP lobby is way worse than even Slashdot thought.
"...iatrogenic illness constitutes the third-leading cause of death in the United States; heart disease and cancer are the first- and second-leading causes of death, respectively.[17]"
"In the United States, figures suggest estimated deaths per year of: [17][18] [19][20] 12,000 due to unnecessary surgery 7,000 due to medication errors in hospitals 20,000 due to other errors in hospitals 80,000 due to nosocomial infections in hospitals 106,000 due to non-error, negative effects of drugs"
The problem with this line of thinking is it assumes perfectly healthy 100% efficient cells.
But that's not always the case. This is why older people need to take vitamins, as we age our cells become less efficient and we have to supply a bit more. I didn't get this from the "vitamin and supplement" industry it's in the book the biochemist who discovered 2 of the B vitamins wrote.
"Moreover, these changes were accompanied by depletion of ceramides."
What happens if you put them back?
That is, two things seem to happen. An increase in ganglioside GM2 and depletion of ceramides.
In very rough terms overproduction of something tends to work itself out if the stimulus is mitigated. That is, if a bomb was going off every day and GM2 was constantly being produced, I'd worry, but a one time increase? Let's assume that goes away over time.
The depletion of of something is more interesting I think. It's unclear what they mean by depletion, whether they mean "there's less of it" or "there's none of it left" (is that even possible?).
At any rate, my first thought would be "put the stuff back" and see what happens. Of possible interest here is David Horrobin's 1985 paper on a phospholipid hypothesis for mental disorders. He maintains that a disruption in the bilipid layer where fatty acids are replaced with other molecules (trans fat being the worst) causes changes that render neurotransmitter receptors, large proteins that exist in the bilipid layer, compromised, and far far less efficient. This would also explain type II diabetes, especially the "the body makes enough insulin but can't seem to use it" part. And it would also explain depression, where the serotonin level is normal but the person is depressed until SSRI's increase the amount of serotonin to near dangerous levels.
The correct phospolipds would come from marine sources (oily fish: sardines, trout, salmon, tuna, mackerel etc) and certain terrestrial seeds (flax, chia) but not in many other places, there's a small amount in grass fed, but not corn fed, beef for example). Over time, consumption of these should replenish the bilipid layer with the correct phospholipids, but this will take months.
Both the Norovirus and the Flu swept though here over xmas, we're all fine now, it was fairly mild. I saw my doc today for the annual checkup thing and joked about the empty waiting room and how everyone must be over it. He said no, they're all at emerg and he saw 46 people yesterday with it and it's the worst it's been for years.
He said it's Type A flu.
These seemed to help, me at least, maybe that's why it was fairly mild around here while other folks seemed to be having a harder time of it.
I have no idea why but chilis, garlic and ginger help A LOT too. But you have to get fairly large amounts into you. 3 or 4 garlic cloves a day and commensurate amounts of the others. This also seems to go a long way towards preventing a secondary infection too. I *always* used to get them, now, I don't since I started doing this about 7 years ago. Not once.
Flu rarely kills. It's the secondary infection that gets you. Lots of vitamin C and garlic goes a long way there, C is essential in the immune system and whenever the body heals and gets used up very quickly; you want lots in your system when it heals after the virus makes a mess, that's when you'll get a secondary infection if you're going to get one.
When flu does kill it's because of a Cytokine storm which is a feed forward loop where the immune system tries to kill itself and you drown in fluid in the lungs. Two things have been shown to stop this: niacin and smoking a cigarette. They hate to admit this, but it's true and there's ongoing research into nicotiine, nicotinic acid and related compounds to stop this.
The most conservative study shows C itself knocks a day off. Take really big, (15g/day) doses and it works even better. Two years ago when H1N1 went through here I was sick for 2 days with it. My ex died from it. I found the list of vitamins to take I gave here on her fridge when me and the kids cleaned out out. She never got any of them.
Also, olive leaf extract has been clinically shown to prevent flu in 20% of cases, but doesn't do a damn thing for you when you have it.
So the files are huge, so what? My first webserver drive was obe gig, cost a grand and took 3 years to fill up. Now we'll download a movie that's six gigs and not blink.
Files get bigger, pipes get bigger per demand. It's been this way since, oh, 1974.
Doug Crockford has a pretty good talk on why Java is crap. It's online. And he's quite right.
I found the damn thing so annoyingly bad I ended up blackholing java.com just to it never installs itself again. I was tired of deleting it. Funny how those odd freezes and crashes went away since I did this and i turns out I miss nothing. Maybe twice a year something goes "y u no have java?" and I close the window. Good riddance.
See, displying "Yay! it fit in the memory they gave me!" can't be 7 megs.
C was only ever a shorthand for PDP-11 machine language, (back when C was young we'd routinely look at the compiler output. At that point it was passing arguments in registers and Dave Conroy sat in the next cube over working on what has today morphed into* gcc. That's one long lived piece of code.) and in tight spaces and critical loops you want machine language.
Romable node.js would be the only thing I'd consider other the C for embedded code. I don't mind paying that overhead for the inherent asynchronous I/O advantages;, you have to muck around in C a lot to do that so it's worth the trade-off. Anything else just didn't bring enough to the table to warrant the overhead IMO.
Contemporary support for C outside of Bell labs was because of embedded code (a camera gantry project, later, the Halifax postal processing plant) - the RSX11M C compiler written for that became DECUS C which went public and then went everywhere, including replacing the Bell compiler.
* Yeah I know the claim is gcc is a clean rewrite, but logging into toad.com in the early 90s I found DGC commented source in the mix. Jon wasn't aware of it apparently...
If I wasn't sure I would have said "I'm not sure but I think...". I went to Waterloo because I wanted to study computer languages and did. I've written a few 25 years ago one of which is still in use today that looks a lot like Java. You?
I'm not saying I've used them all extensively, but I've looked at them enough to know what they're all about and found them all wanting. Once Javascript grew up a bit and stabilized I took a hard look at it. It's about the state of the art the culmination of three decades of advances in computer language design. That and the V8 engine and now node makes it a force to be reckoned with and it's only a matter of time till business figures this out. It took most of them 20 years to discover unix so this won't happen quickly but it will happen. I'd put money on it.
Oh, you want a hard copy? Go this this and click print. No I'm not going to mail you one, you want hard copy use your own paper and ink.
Everything's in webspace. I gave up paper in late 1990.
I did buy an Epson pigment ink pritner to print photos for fun, but absolutely everything is a file; I use about a a square foot and a half of paper a year. Mostly writing very short grocery list and perhaps the odd phone number.
The first year was admittedly hard, but after that... pffffft. What a difference. And you DO get used to it.
If you can't knock out something to manage all your paper online and get it up and running in about 6 months, you're incompetent.
Slashdot Mirror
Additionally there are other mechanisms. Take a dozen peaches, peel them and put them in a baggie in the freezer. Thaw them out a week later. Notice they're al brown? Now do the same thing but add vitamin C to them as anybody would who followed the recipe in the book. Now notice when you thaw them out they're the original color. That haven't oxidized.
The same thing happens in animal bodies, so it's not always the matter of supplying an essential molecule hoping a reaction will take place, sometimes you can just flood the system and the mere physical presence of that much of the molecule does useful things - Pauling showed with clinical trials (available online at the Pauling institute) that C alone in large doses will kill many viruses, and specifically Polio.
C is also about the best line of defence against insect and even snake bites.
Of course as a natural (as in, it's in the body anyway) medicine, the body which knows what to do with the molecule so there's no side effects unlike synthetic medicines which all have side effects and along with botched surgery make modern medicine the third leading cause of death in the United States today. The thing is, you can patent synthetic medicine; the IP lobby is way worse than even Slashdot thought.
http://en.wikipedia.org/wiki/Iatrogenesis
"...iatrogenic illness constitutes the third-leading cause of death in the United States; heart disease and cancer are the first- and second-leading causes of death, respectively.[17]"
"In the United States, figures suggest estimated deaths per year of: [17][18] [19][20]
12,000 due to unnecessary surgery
7,000 due to medication errors in hospitals
20,000 due to other errors in hospitals
80,000 due to nosocomial infections in hospitals
106,000 due to non-error, negative effects of drugs"
They don't need to. There are processors outside the US.
Its easier to get money FROM consumers than to pay it TO them for gambling.
Not that US online gambling stopped, it just got more complicated.
Have you read the fine print?
The problem with this line of thinking is it assumes perfectly healthy 100% efficient cells.
But that's not always the case. This is why older people need to take vitamins, as we age our cells become less efficient and we have to supply a bit more. I didn't get this from the "vitamin and supplement" industry it's in the book the biochemist who discovered 2 of the B vitamins wrote.
Because it's biochemistry nor politics? Is this a trick question?
Is it just bombs? What if firing guns at a gun range does it too?
Anxiety leads to depression which leads to anger which leads to violence.
Could it be possible that shooting guns recreationally messes up the biochemistry of peoples heads with any number of negative possible outcomes?
" It's going to be much harder than feeding salmon to shell shocked mice."
Because you've tried this?
Or are you guessing?
I don't think mice like salmon and would probably try flax seed. Cheap and easy test to run though, no?
"Moreover, these changes were accompanied by depletion of ceramides."
What happens if you put them back?
That is, two things seem to happen. An increase in ganglioside GM2 and depletion of ceramides.
In very rough terms overproduction of something tends to work itself out if the stimulus is mitigated. That is, if a bomb was going off every day and GM2 was constantly being produced, I'd worry, but a one time increase? Let's assume that goes away over time.
The depletion of of something is more interesting I think. It's unclear what they mean by depletion, whether they mean "there's less of it" or "there's none of it left" (is that even possible?).
At any rate, my first thought would be "put the stuff back" and see what happens. Of possible interest here is David Horrobin's 1985 paper on a phospholipid hypothesis for mental disorders. He maintains that a disruption in the bilipid layer where fatty acids are replaced with other molecules (trans fat being the worst) causes changes that render neurotransmitter receptors, large proteins that exist in the bilipid layer, compromised, and far far less efficient. This would also explain type II diabetes, especially the "the body makes enough insulin but can't seem to use it" part. And it would also explain depression, where the serotonin level is normal but the person is depressed until SSRI's increase the amount of serotonin to near dangerous levels.
The correct phospolipds would come from marine sources (oily fish: sardines, trout, salmon, tuna, mackerel etc) and certain terrestrial seeds (flax, chia) but not in many other places, there's a small amount in grass fed, but not corn fed, beef for example). Over time, consumption of these should replenish the bilipid layer with the correct phospholipids, but this will take months.
Both the Norovirus and the Flu swept though here over xmas, we're all fine now, it was fairly mild. I saw my doc today for the annual checkup thing and joked about the empty waiting room and how everyone must be over it. He said no, they're all at emerg and he saw 46 people yesterday with it and it's the worst it's been for years.
He said it's Type A flu.
These seemed to help, me at least, maybe that's why it was fairly mild around here while other folks seemed to be having a harder time of it.
http://rs79.vrx.net/opinions/ideas/medicine/vitamins/flu/
http://rs79.vrx.net/opinions/ideas/medicine/ginger/
I have no idea why but chilis, garlic and ginger help A LOT too. But you have to get fairly large amounts into you. 3 or 4 garlic cloves a day and commensurate amounts of the others. This also seems to go a long way towards preventing a secondary infection too. I *always* used to get them, now, I don't since I started doing this about 7 years ago. Not once.
Flu rarely kills. It's the secondary infection that gets you. Lots of vitamin C and garlic goes a long way there, C is essential in the immune system and whenever the body heals and gets used up very quickly; you want lots in your system when it heals after the virus makes a mess, that's when you'll get a secondary infection if you're going to get one.
When flu does kill it's because of a Cytokine storm which is a feed forward loop where the immune system tries to kill itself and you drown in fluid in the lungs. Two things have been shown to stop this: niacin and smoking a cigarette. They hate to admit this, but it's true and there's ongoing research into nicotiine, nicotinic acid and related compounds to stop this.
The most conservative study shows C itself knocks a day off. Take really big, (15g/day) doses and it works even better. Two years ago when H1N1 went through here I was sick for 2 days with it. My ex died from it. I found the list of vitamins to take I gave here on her fridge when me and the kids cleaned out out. She never got any of them.
Also, olive leaf extract has been clinically shown to prevent flu in 20% of cases, but doesn't do a damn thing for you when you have it.
So the files are huge, so what? My first webserver drive was obe gig, cost a grand and took 3 years to fill up. Now we'll download a movie that's six gigs and not blink.
Files get bigger, pipes get bigger per demand. It's been this way since, oh, 1974.
Follow the money.
Doug Crockford has a pretty good talk on why Java is crap. It's online. And he's quite right.
I found the damn thing so annoyingly bad I ended up blackholing java.com just to it never installs itself again. I was tired of deleting it. Funny how those odd freezes and crashes went away since I did this and i turns out I miss nothing. Maybe twice a year something goes "y u no have java?" and I close the window. Good riddance.
"But if you're starting new big applications for the PC in C, you're probably insane."
Or you know how to use the langauge.
Work with me here: C++ was a bunch of preprocessor directives tacked on to C.
That and Macros can make C look like anything you want. It's not true extensibility but it's been
getting the job done for decades and works fine.
It's amazing all those apps written in C ever managed to exist before Java. It must be some sort of a miracle.
$1 says in 10 years java will be a faint and bad memory, having been replaced by JavaScript.
No, she held out for the bigger one, this is only the second biggest.
http://en.wikipedia.org/wiki/Colossal_squid
Oh snap.
See, displying "Yay! it fit in the memory they gave me!" can't be 7 megs.
C was only ever a shorthand for PDP-11 machine language, (back when C was young we'd routinely look at the compiler output. At that point it was passing arguments in registers and Dave Conroy sat in the next cube over working on what has today morphed into* gcc. That's one long lived piece of code.) and in tight spaces and critical loops you want machine language.
Romable node.js would be the only thing I'd consider other the C for embedded code. I don't mind paying that overhead for the inherent asynchronous I/O advantages;, you have to muck around in C a lot to do that so it's worth the trade-off. Anything else just didn't bring enough to the table to warrant the overhead IMO.
Contemporary support for C outside of Bell labs was because of embedded code (a camera gantry project, later, the Halifax postal processing plant) - the RSX11M C compiler written for that became DECUS C which went public and then went everywhere, including replacing the Bell compiler.
* Yeah I know the claim is gcc is a clean rewrite, but logging into toad.com in the early 90s I found DGC commented source in the mix. Jon wasn't aware of it apparently...
Post two verifiable facts. Get modded flamebait. Oh, Slashdot.
"The first corals were soft bodied, which probably helped."
You might wanna check that.
You don't get to leave out the effect of CO2 on growing trees and call yourself an expert on CO2.
You really think the current models are right now. Ooooooook.
Can you show me the warming trend in this:
http://rs79.vrx.net/opinions/ideas/climate/.images/HolocenePeriods.png
Please respond. Every time I show this to alarmists they go silent.
If I wasn't sure I would have said "I'm not sure but I think...". I went to Waterloo because I wanted to study computer languages and did. I've written a few 25 years ago one of which is still in use today that looks a lot like Java. You?
I'm not saying I've used them all extensively, but I've looked at them enough to know what they're all about and found them all wanting. Once Javascript grew up a bit and stabilized I took a hard look at it. It's about the state of the art the culmination of three decades of advances in computer language design. That and the V8 engine and now node makes it a force to be reckoned with and it's only a matter of time till business figures this out. It took most of them 20 years to discover unix so this won't happen quickly but it will happen. I'd put money on it.
You'll never need more than 640K.
Sheer idiocy. Javascript won ages ago and people are only now waking up to this fact? You new here?
It really is quite brilliant and the only language I thought was worth using since I learned C in 1976, and I've tried them all.
It would perhaps to watch the 8 hours of Doug Crockfords videos to catch up on why this is true.
My kid's reaction: "I would too. No regrets."
Oh, you want a hard copy? Go this this and click print. No I'm not going to mail you one, you want hard copy use your own paper and ink.
Everything's in webspace. I gave up paper in late 1990.
I did buy an Epson pigment ink pritner to print photos for fun, but absolutely everything is a file; I use about a a square foot and a half of paper a year. Mostly writing very short grocery list and perhaps the odd phone number.
The first year was admittedly hard, but after that... pffffft. What a difference. And you DO get used to it.
If you can't knock out something to manage all your paper online and get it up and running in about 6 months, you're incompetent.
Ok, how bout instead it shows they're justifiably scare of the gun crazies. Or as the NRA calls them "responsible gun owners".
"Java is dead" - FreeBSD
Rightly so too. Utter rubbish.
...if we could find the gun and war center.
Somebody needs to tell Kat Herding.