If you read the article carefully you will note that the experiment proved that the effects of the disorder could be reversed if a treatment is found. Whereas everyone expected them to be permanent.
They did not however find a cure for rett syndrome, they found a cure for a fake rett syndrome they created in a cleverly reversible way. They inserted blocking genes in front of the gene responsible for the disorder and then used a treatment which could actually remove the block in the grown mice that grew from those genes, they did nothing to the actual gene. If the genes they started with had been mutated to begin with then the treatment wouldn't have cured them.
The article makes a big deal about it sort of being a cure, at least for the mice involved, but whats really interesting here is the fact that damage from genetic neurological disorders might not be irreversible if treatments can be found.
so yeah one day you will all stop reading the internet compulsively and gaming 24/7 and just sit calmly in front of the television like normal people.
Id like to see microsoft ban the use of machines with their software on them by anyone who hasn't approved the EULA. The more 1984 they get the less people will want to use them.
I the commet's water didn't contain life in the first place, mayby we just contaminated it with whatever cleaver microbes hitched a ride on the impactor. That'd be sweet.
whatever happened to exercising without a $500 machine, it might make America's youth less of technology addicts (current company excluded, of course).
what kills me is these freaks actually claim they aren't trying to limit our ability to create by forceing us to buy into some drm system. The wording of the law covers computers and recording equipment, and i dont see how that isn't going to increase the cost and complexity of those devices used for creating the content they claim they are trying to protect. I cant see this being a thing artists would want, and recall Artists' work is what this is all supposedly about. It seems to me that this is a scam to give the MIDDLEMEN a bigger piece of the pie.
i did it once with a cheap drive. i was able to replace the entire cover plate with a pice of acrylic. it worked just fine, the trick is not to let any dust in. have everything sanded and cleaned before you void the warranty.
as i observed it AJAX caught on when firefox, safari et al began supporting an equivalent system of http geting. i think really it was that noone wanted to write badass sites that would only work in IE then write another version for the rest of the world, belive me i figured out a way to do it back in the day with iforms but it was just too much of a hassle to figure out the best way to do it for all browsers. the method became popular when it became possible to sift out workable ways to do it on many browsers, and it'll get more popular when people figure out the best way to integrate it with the existing web gui paradigm.
Someone came up with one more hack to extend the functionality of HTML/JS and *GASP* developers arent using best practices. no way. Its almost like this whole web thing is one hack on top of another on top of a basic system not designed for the purpose it has been put to.
The web is literally evolving and the genome representing 'AJAX best practices' just hasent been selected out yet. Its like the whole table vs div+style thing.
It seems likely that it would be an advantage to have a mechanism to encourage long term memory building during such a time, as falling in love does represent a major permanant change in ones day to day life, and one would do well to learn as much as possible during that time. I'm not saying I am aware of a link between NGF and mamory creation or retention, just that it would make sense.
take one of your old pc's and remove its 500w, manually switched, multiple voltage power supply and hope everything you've got can run at some combination of (i think) 5v, 12v, -5v and -12v. you could make several combinations (12 - -5 = 17v, 12 - 5 = 7v), i belive all it would take is a voltmeter. i've used these for hobby power supplies for years and the only trouble ive had is that they require some load to work properly.
cool, this just means that i'll have a source for cheap gps units after they realize that this system is un-enforceable and have to get rid of all those recivers. i have so many projects that could benefit from a cheap gps solution. THANKS CALIFORNIA
---
"Take California" -Propellerhead
the country has internet therefore there is probably an internet shop in the capital city. i would find one and pay them to print out the material and then have it shiped from there.
im not going to hold your hand and walk you through the steps neccesary to prove this but picmicros have the power and ability to speak to any family of logic i can think of.
i aggree , i have built a few things out of old dram , but the time & effort it would take to throw this together outweighs the near free costs of the materials. this would only be easy for someone who had done both ide and memory controlling before and had the chips, programmers etc. around.
BTW. a 'ram refresher system' would be part of the controller already due to the extremely short time ram stays charged for (think milliseconds) so all that would be required to keep the data is a battery source powering the pic controller and memory chip.
not to flame or anything but where do you get the idea that you need fpgas and glue logic to make two pic controllers talk to eachother? and there _are_ pic chips with like 80 i/o pins going for about 10 bucks.
download the infosheet on the ram you have from the company that made it or a company that makes equivalent. it will they'll you the timing neccesary to read, write and refresh the memory, something like bring 'cas' pin high for x nano-seconds then write the first y bits of the address then bring 'ras' high and write the rest of the address then read from or write to the data pins. Then get a picmicro controller and write a program to controll the memory and talk ide, load it on the micro-controller, then wire up a memory socket and an ide plug. total cast: +- $25 total time: 3hrs - 2months depending on expiriance
i just don't see any evidence that we can advance our machines any faster than evolution did it in the first place(never call evolution slow). in that case it will take on the order of billions of years to catch up, that is never to me. furthermore it is extremely likely that we will, in the interveneing time, figure out how the existing technology works and never get around to 'reinventing the cell' as it were.
the best sensors that exist, as far as we know, are biological. in fact, the technology boom started 4 billion years ago. We will
never
build a more advanced machine than a cell, the real challenge is to learn how to program the abundant hardware lying around to do something useful. these fish are a step in that direction.
Slashdot Mirror
If you read the article carefully you will note that the experiment proved that the effects of the disorder could be reversed if a treatment is found. Whereas everyone expected them to be permanent.
They did not however find a cure for rett syndrome, they found a cure for a fake rett syndrome they created in a cleverly reversible way. They inserted blocking genes in front of the gene responsible for the disorder and then used a treatment which could actually remove the block in the grown mice that grew from those genes, they did nothing to the actual gene. If the genes they started with had been mutated to begin with then the treatment wouldn't have cured them.
The article makes a big deal about it sort of being a cure, at least for the mice involved, but whats really interesting here is the fact that damage from genetic neurological disorders might not be irreversible if treatments can be found.
so yeah one day you will all stop reading the internet compulsively and gaming 24/7 and just sit calmly in front of the television like normal people.
Id like to see microsoft ban the use of machines with their software on them by anyone who hasn't approved the EULA. The more 1984 they get the less people will want to use them.
I don't 'sign' the EULA when i use a public machine...
now taking bets on how soon the archeologists start dropping dead
I the commet's water didn't contain life in the first place, mayby we just contaminated it with whatever cleaver microbes hitched a ride on the impactor. That'd be sweet.
whatever happened to exercising without a $500 machine, it might make America's youth less of technology addicts (current company excluded, of course).
what kills me is these freaks actually claim they aren't trying to limit our ability to create by forceing us to buy into some drm system. The wording of the law covers computers and recording equipment, and i dont see how that isn't going to increase the cost and complexity of those devices used for creating the content they claim they are trying to protect. I cant see this being a thing artists would want, and recall Artists' work is what this is all supposedly about. It seems to me that this is a scam to give the MIDDLEMEN a bigger piece of the pie.
i did it once with a cheap drive. i was able to replace the entire cover plate with a pice of acrylic. it worked just fine, the trick is not to let any dust in. have everything sanded and cleaned before you void the warranty.
as i observed it AJAX caught on when firefox, safari et al began supporting an equivalent system of http geting. i think really it was that noone wanted to write badass sites that would only work in IE then write another version for the rest of the world, belive me i figured out a way to do it back in the day with iforms but it was just too much of a hassle to figure out the best way to do it for all browsers. the method became popular when it became possible to sift out workable ways to do it on many browsers, and it'll get more popular when people figure out the best way to integrate it with the existing web gui paradigm.
Someone came up with one more hack to extend the functionality of HTML/JS and *GASP* developers arent using best practices. no way. Its almost like this whole web thing is one hack on top of another on top of a basic system not designed for the purpose it has been put to. The web is literally evolving and the genome representing 'AJAX best practices' just hasent been selected out yet. Its like the whole table vs div+style thing.
It seems likely that it would be an advantage to have a mechanism to encourage long term memory building during such a time, as falling in love does represent a major permanant change in ones day to day life, and one would do well to learn as much as possible during that time. I'm not saying I am aware of a link between NGF and mamory creation or retention, just that it would make sense.
take one of your old pc's and remove its 500w, manually switched, multiple voltage power supply and hope everything you've got can run at some combination of (i think) 5v, 12v, -5v and -12v. you could make several combinations (12 - -5 = 17v, 12 - 5 = 7v), i belive all it would take is a voltmeter. i've used these for hobby power supplies for years and the only trouble ive had is that they require some load to work properly.
if intellectual property existed we'd still be in the fucking stone age buying fire from prometheus Corp.
cool, this just means that i'll have a source for cheap gps units after they realize that this system is un-enforceable and have to get rid of all those recivers. i have so many projects that could benefit from a cheap gps solution. THANKS CALIFORNIA --- "Take California" -Propellerhead
the country has internet therefore there is probably an internet shop in the capital city. i would find one and pay them to print out the material and then have it shiped from there.
im not going to hold your hand and walk you through the steps neccesary to prove this but picmicros have the power and ability to speak to any family of logic i can think of.
i aggree , i have built a few things out of old dram , but the time & effort it would take to throw this together outweighs the near free costs of the materials. this would only be easy for someone who had done both ide and memory controlling before and had the chips, programmers etc. around. BTW. a 'ram refresher system' would be part of the controller already due to the extremely short time ram stays charged for (think milliseconds) so all that would be required to keep the data is a battery source powering the pic controller and memory chip.
not to flame or anything but where do you get the idea that you need fpgas and glue logic to make two pic controllers talk to eachother? and there _are_ pic chips with like 80 i/o pins going for about 10 bucks.
download the infosheet on the ram you have from the company that made it or a company that makes equivalent. it will they'll you the timing neccesary to read, write and refresh the memory, something like bring 'cas' pin high for x nano-seconds then write the first y bits of the address then bring 'ras' high and write the rest of the address then read from or write to the data pins. Then get a picmicro controller and write a program to controll the memory and talk ide, load it on the micro-controller, then wire up a memory socket and an ide plug. total cast: +- $25 total time: 3hrs - 2months depending on expiriance
more IT, for companies without enough buget for my employers services
i just don't see any evidence that we can advance our machines any faster than evolution did it in the first place(never call evolution slow). in that case it will take on the order of billions of years to catch up, that is never to me. furthermore it is extremely likely that we will, in the interveneing time, figure out how the existing technology works and never get around to 'reinventing the cell' as it were.
- never
build a more advanced machine than a cell, the real challenge is to learn how to program the abundant hardware lying around to do something useful. these fish are a step in that direction.