The human genome is quite variable from person to person and across ethnic groups. A given gene may have many subtle variant forms called polymorphisms. Oftentimes, these polymorphisms differ by only one base pair, in which case they are called single nucleotide polymorphisms or SNPs. The gene product of a SNP can function almost like the "normal" gene, but not quite. Linking certain SNPs with disease susceptibility is currently a hot area of research. Both Celera and the NIH maintain SNP databases that are growing exponentially.
But in no situation is giving money to a small univ prof signiciantly better than giving more money to a large univ prof. The large univ selected a better professor because hes better, and therefore worth more.
What? No. Unlike in the private sector, when a professor is at a university long enough, he/she gets tenure. Just because someone was hired 10 years ago by a certain university doesn't mean their work is still up to the same standard. Or maybe they were hired because they were working in a hot area which has since fizzled. I know of plenty of scientists who are "one-trick ponies" and they've gotten tenure in a short time. Ten years from now I'd put my money elsewhere. Furthermore, smaller universities do not necessarily get the leftovers of larger universities. When a scientist is offered a position from multiple institutions, there are many factors to consider besides the size or prestige of a university. Smaller universities that are trying to grow in a certain area tend to give much larger startup packages than universities with more established programs. Sometimes a professor will move to a smaller university because he is offered a position as a chairman. Or sometimes people factor in location or who their colleagues will be. It's more complicated than you make it out to be.
I watched on-off last season out of loyalty, but this season I gave up. But tonight there was a preview on that showed the lonegunmen and I thought "oooo I like the lonegunmen" so I watched it. Now I wonder if Fox killed them off so people would stop bugging them to put the Lonegunmen show back on the air...
Not that I know of. Divx;-) encoded versions are available on irc (I got mine on dalnet channel #x-files-central ) If you have a dvd player that will play vcds, you can use TmpEnc to convert them to mpeg format then use nero to burn a vcd. There are more detailed instructions and a list of vcd compatible players at http://www.vcdhelp.com
My geek boyfriend ordered my present the other day - a padded sleeve for my new ibook so I can carry it around in my backpack. I saw it while I was browsing around on the wireless network he set up in the apartment and I said "oooo I want one of those." So he handed me his credit card and said happy valentines day. For my bithday last month I got RAM and x-files dvds. Plus I get flowers and stuff on a semi-regular basis. And he fixes things. I love my geek . Every girl should have one:-)
I think later I'll go to some jewelry sites and see if the "oooo I want that" works again...
they should publish the results in a peer-reviewed journal like Science, Nature, PNAS, or Cell.
PNAS isn't peer reviewed.
At our university (I'm a grad student) the public relations office encourages press releases about exciting research findings. These press releases usually coincide with the publication of the research in a reputable journal or a scientific conference. I see nothing wrong with drawing the mainstream media's attention to science in this way. However, these "stand alone" press releases do seem sensationalized, but they are becoming common.
The Post Office, due to poor management, is running a _BILLION_ dollar deficit right now
Then why do they do things like sponsor the Olympics? I wouldn't be annoyed with postage increases if they weren't subsidizing stupid PR stunts like this.
My boyfriend had DSL service from Qwest, and he just told them he had a mac, and since there's no MSN for the mac, they let him keep the qwest service. I bet you can just lie and tell them you have a mac, then type in the IP settings and stuff into your PC.
I read CNN's page about the Medicine prize, and all I got was that the winners had something to do with cancer. For real "in-depth" information on the prizewinners and their discoveries, forget CNN and go to the Nobel site at http://www.nobel.se/ (Click on the category then laureates) They have the presentation speeches and other content for those of us who can read above the 6th grade level. The illustrated presentations are especially cool.
Do Univiersities need to add more "career development" type classes? Probably. Should this be done at the expense of a well-rounded curriculum? Absolutely not! Excuse me while I stereotype for a minute, but people who know a lot about only one thing are often narrow-minded and boring. Sure, those other people that you hang out with who are just like you - they might find you interesting, but the rest of us don't.:-P
The "well-rounded education" is not there soley for people who haven't decided on a career yet. It is there to teach you how to think about a variety of different things in a variety of different ways. It helps you out in your future life by allowing you to hold an intelligent conversation with people whose interests are divergent from yours. It allows you to better understand world events, enjoy a good book or play, or whatever it is you decide you like to do when you aren't working. If you think this is a waste of your time, then you belong at a vocational school, not a university.
Some universities decide to do this by having a core curriculum, and my friends who went to U Chicago loved theirs. My alma mater, Johns Hopkins, did it differently. Each class and major was categoriezed as history, writing, science, etc. We had to take a certain amount of classes in each of these areas. As a result, we got a well-rounded education while retaining some choice over our curriculum. Hate Post Modern Literature? Fine. Take the Anthropology of Sex instead. (I did.) Many of these classes had no direct practical application to the career path I had already chosen, but after a 6 hour organic chemistry lab, they were pretty fun. I just went to Eurpoe for the first time, and I am so glad I took Art History instead of another undergraduate science class full of information that has either become outdated in the last 4 yeats or been repeated during graduate school.
From some of the comments here, it seems like there is a demand for management and business training. I think this type of training should supplement, not replace a traditional university education. And there *are* schools that offer MBAs. Perhaps the training you seek is already there?
Just my $0.02,
-m.
--
no sig, just a website: http://www.bluehurricane.com
I don't envision the market actually paying for (and abiding by) license-to-use until we have some sort of never-degrading, indestructible (or at least, trivially easy to back up) medium for holding the licensed product.
But we don't have that now. I don't expect the RIAA to give me a new CD when mine gets a skip.
Maybe the micropayment services could compete with one another for your business by offering various guarantees for the replacement of lost media. They could easily recoup the cost of this by selling the list of stuff you bought to some ad people.
You think Netscape avoids bloated sites???? No way. With a non CSS compliant browser like netscape, you have to fill your pages with font tags and table formatting and other clutter, wheras a CSS compliant browser can take all this info from a single linked stylesheet. I realize that IE is not 100% compliant (on the PC anyway), but it is leaps and bounds ahead of netscape4.x!
You end up with a show that has two distinct sides: "conspiracy" episodes, and the "x-file" episodes. I find the x-file episodes boring, because 1) they don't matter in the long-run, and 2) they are frequently silly/inane (witness that rediclous FPS episode, or the sad, sad, sad end-of-last-season episode involving Scully and Mulder being the subject of a Tea Leoni and Gary Shandling movie). There are a few exceptions (I think this season's baseball-loving alien was one of the show's best ever) but all in all, the conspiracy episodes are the only ones worth watching. Too bad those only air during sweeps, and then only a total of 4 or 5 this year.
Probably about half the x-files fans I know agree with you, and the other half likes the "x-file" episodes better, so it's good that they do both. More viewers that way. Me - I like both kinds, although lately the conspiracy episodes have seemed a bit forced.
One important point made: if a jury believes the law to be unjust or unjustly applied, they can reach a not guilty verdict even if they believe without a doubt that the person in question committed the act.
I think the term for that is "jury nullification."
I dunno - I bet Jack McCoy would go for Murder 2 on the grounds of "depraved indifference to human life." (Disclaimer - Like you, the bulk of my legal knowledge comes from Law & Order reruns.)
Wonder who would get jurisdiction - the state where the hacker/cracker lived or the state where the hacked computer lives? Or would it be federal? If Mir or the ISS were involved, jurisdiction could get real hairy. Oh well, we'll just have to wait for the Law & Order episode and all our complex legal questions will be answered;-)
I actually met Dr. Joe Tsien, creator of the "doogie" mouse a few months ago. (Another neuroscience grad student and I invited him to give a seminar at our university.) Apparently, Daniel Keys read about Dr. Tsien's work (there was a lot of media hoop-la) so he called him up to ask him some technical questions. Turns out he was writing the last couple of chapters of the sequel to Flowers for Algernon when the story broke. A timely book, it seems.
EXCUSE ME?!? I hope this was an attempt at sarcasm. I vote for whoever I damn well please. So does my mom. And I'm pretty sure that Mary Matalin doesn't vote for whoever James Carville tells her too.
Speaking of domain names, I stumbled upon this today. If you go to domaindirect.com and type in billbradley, it of course says that.com.net and.org are taken. If you click on each one, it does a whois search. (I was looking for an email address to send a friend's as yet unanswered complaint about their campaign mailing list's bad grammar and spelling, but that's another story.)
Anyway, here is what you get for billbradley.com: Registrant: Bill Bradley for President (BILLBRADLEY-DOM) 395 Pleasant Valley Way West Orange, NJ 07052 US
Domain Name: BILLBRADLEY.COM
Administrative Contact, Technical Contact, Zone Contact: Gore, Al (LR1487) haxormad@HOTMAIL.COM AlGore2000.com 2410 Charlotte Avenue Nashville, 37203 37203
202.644.9658
Record last updated on 02-Feb-2000. Record created on 03-Mar-1997. Database last updated on 26-Feb-2000 12:34:27 EST.
HOLY SMOKES! Does this mean that Al Gore bought billbradley.com in 1997 and then sold it to them? I don't know much about this type of thing, which is why I'm asking here. The entries for.net and.org say pretty much the same thing:
Domain Name: BILLBRADLEY.NET
Administrative Contact: Turlington, Ed (ET1357) edturlington@BILLBRADLEY.COM The Office of Bill Bradley 1661 Page Mill Road Palo Alto,, CA 94304
650-494-2554 (FAX) 650-494-1739 Technical Contact, Zone Contact: Registrar, Domain (DR1432) shore-dns@SHORE.NET Shore.Net 173 Oxford Street Lynn, MA 01901
781-477-2000 (FAX) 781-593-6858
Record last updated on 05-May-1998. Record created on 05-May-1998. Database last updated on 27-Feb-2000 17:29:17 EST.
Am I interpreting this corectly - the Gore people bought billbradley.com in 1997, then sometime before May 1998, the Bradley people bought it from them then also bought.org and.net?
I used domaindirect.com to register my domain. It was $70 for 2 years, which after reading the other posts, I suppose is expensive.
Anyway, domaindirect is run by TUCOWS and I've had nothing but excellent service. If you don't have an IP address to give thenm they will set up a "coming soon" page for you, or you can have it forward to another page. You can also set it up so that your domain name stays in the browser address bar after it forwards. (I think they use an invisible frame or something.) You can edit the meta tags for the forwarding page too.
As far as email, you get 5 addresses to make up at your domain name. You can either specify a location to forward to, or else use POP mail to check them.
Kary Mullis got some compensation - a rather large bonus from Cetus and a Nobel Prize. But no royalities from the patent. In interviews he's said that the powers that be at Cetus originally thought he was wasting his time on PCR, and he that he feels shafted by them. I'm not sure how much he had to do with Taq though - he left a few years before the Taq patent was applied for. (The original PCR process did not involve Taq.)
And just becasue Promega has a patent on Taq polymerase, it doesn't mean you can't make your own. My lab has a freezer full of Taq that we made. It's pretty simple - clone the gene, express it in E. Coli, purify the proteins, heat-kill the unwanted proteins, and viola - hundreds of thousands of dollars worth of Taq. As far as I know, as long as we don't try to sell it, this is perfectly legal.
I don't understand these posts which say that Mozilla, in its current state, is better than IE. Everytime I try Mozilla, there are pages which work fine in both IE and NS, but which Mozilla doesn't render correctly. And Mozilla inevitably crashes after I spend any time using it.
Maybe it has something to do with procesor speed? I've read that gecko's supposed to be really fast, but mozilla runs slow as molasses on my system. (I am stuck using a POS pentium 90 though.) By itself, however, viewer.exe runs at a decent speed, so maybe slower processors can't handle rendering the "chrome" and other extras...
But I'm just guessing. Any mozilla people out there?
Slashdot Mirror
The human genome is quite variable from person to person and across ethnic groups. A given gene may have many subtle variant forms called polymorphisms. Oftentimes, these polymorphisms differ by only one base pair, in which case they are called single nucleotide polymorphisms or SNPs. The gene product of a SNP can function almost like the "normal" gene, but not quite. Linking certain SNPs with disease susceptibility is currently a hot area of research. Both Celera and the NIH maintain SNP databases that are growing exponentially.
But in no situation is giving money to a small univ prof signiciantly better than giving more money to a large univ prof. The large univ selected a better professor because hes better, and therefore worth more.
What? No. Unlike in the private sector, when a professor is at a university long enough, he/she gets tenure. Just because someone was hired 10 years ago by a certain university doesn't mean their work is still up to the same standard. Or maybe they were hired because they were working in a hot area which has since fizzled. I know of plenty of scientists who are "one-trick ponies" and they've gotten tenure in a short time. Ten years from now I'd put my money elsewhere. Furthermore, smaller universities do not necessarily get the leftovers of larger universities. When a scientist is offered a position from multiple institutions, there are many factors to consider besides the size or prestige of a university. Smaller universities that are trying to grow in a certain area tend to give much larger startup packages than universities with more established programs. Sometimes a professor will move to a smaller university because he is offered a position as a chairman. Or sometimes people factor in location or who their colleagues will be. It's more complicated than you make it out to be.
I watched on-off last season out of loyalty, but this season I gave up. But tonight there was a preview on that showed the lonegunmen and I thought "oooo I like the lonegunmen" so I watched it. Now I wonder if Fox killed them off so people would stop bugging them to put the Lonegunmen show back on the air...
Not that I know of. Divx;-) encoded versions are available on irc (I got mine on dalnet channel #x-files-central ) If you have a dvd player that will play vcds, you can use TmpEnc to convert them to mpeg format then use nero to burn a vcd. There are more detailed instructions and a list of vcd compatible players at http://www.vcdhelp.com
But if you payed for a small fries at McDonalds they would be pissed if you ate a large.
I think it's more like an all you can eat buffet. And they were betting that most people wouldn't eat like Homer Simspon. Guess they were wrong...
My geek boyfriend ordered my present the other day - a padded sleeve for my new ibook so I can carry it around in my backpack. I saw it while I was browsing around on the wireless network he set up in the apartment and I said "oooo I want one of those." So he handed me his credit card and said happy valentines day. For my bithday last month I got RAM and x-files dvds. Plus I get flowers and stuff on a semi-regular basis. And he fixes things. I love my geek . Every girl should have one :-)
I think later I'll go to some jewelry sites and see if the "oooo I want that" works again...
they should publish the results in a peer-reviewed journal like Science, Nature, PNAS, or Cell.
PNAS isn't peer reviewed.
At our university (I'm a grad student) the public relations office encourages press releases about exciting research findings. These press releases usually coincide with the publication of the research in a reputable journal or a scientific conference. I see nothing wrong with drawing the mainstream media's attention to science in this way. However, these "stand alone" press releases do seem sensationalized, but they are becoming common.
-maragaret
The Post Office, due to poor management, is running a _BILLION_ dollar deficit right now
Then why do they do things like sponsor the Olympics? I wouldn't be annoyed with postage increases if they weren't subsidizing stupid PR stunts like this.
-margaret
My boyfriend had DSL service from Qwest, and he just told them he had a mac, and since there's no MSN for the mac, they let him keep the qwest service. I bet you can just lie and tell them you have a mac, then type in the IP settings and stuff into your PC.
-margaret
I read CNN's page about the Medicine prize, and all I got was that the winners had something to do with cancer. For real "in-depth" information on the prizewinners and their discoveries, forget CNN and go to the Nobel site at http://www.nobel.se/ (Click on the category then laureates) They have the presentation speeches and other content for those of us who can read above the 6th grade level. The illustrated presentations are especially cool.
Do Univiersities need to add more "career development" type classes? Probably. Should this be done at the expense of a well-rounded curriculum? Absolutely not! Excuse me while I stereotype for a minute, but people who know a lot about only one thing are often narrow-minded and boring. Sure, those other people that you hang out with who are just like you - they might find you interesting, but the rest of us don't. :-P
The "well-rounded education" is not there soley for people who haven't decided on a career yet. It is there to teach you how to think about a variety of different things in a variety of different ways. It helps you out in your future life by allowing you to hold an intelligent conversation with people whose interests are divergent from yours. It allows you to better understand world events, enjoy a good book or play, or whatever it is you decide you like to do when you aren't working. If you think this is a waste of your time, then you belong at a vocational school, not a university.
Some universities decide to do this by having a core curriculum, and my friends who went to U Chicago loved theirs. My alma mater, Johns Hopkins, did it differently. Each class and major was categoriezed as history, writing, science, etc. We had to take a certain amount of classes in each of these areas. As a result, we got a well-rounded education while retaining some choice over our curriculum. Hate Post Modern Literature? Fine. Take the Anthropology of Sex instead. (I did.) Many of these classes had no direct practical application to the career path I had already chosen, but after a 6 hour organic chemistry lab, they were pretty fun. I just went to Eurpoe for the first time, and I am so glad I took Art History instead of another undergraduate science class full of information that has either become outdated in the last 4 yeats or been repeated during graduate school.
From some of the comments here, it seems like there is a demand for management and business training. I think this type of training should supplement, not replace a traditional university education. And there *are* schools that offer MBAs. Perhaps the training you seek is already there?
Just my $0.02,
-m.
--
no sig, just a website: http://www.bluehurricane.com
http://news.cnet.com/news/0-1005- 200-2198482.html
One of Napster's defense attorneys (the former microsoft antitrust prosecutor) mentioned it as a possible defense strategy. What timing ;-)
I don't envision the market actually paying for (and abiding by) license-to-use until we have some sort of never-degrading, indestructible (or at least, trivially easy to back up) medium for holding the licensed product.
But we don't have that now. I don't expect the RIAA to give me a new CD when mine gets a skip.
Maybe the micropayment services could compete with one another for your business by offering various guarantees for the replacement of lost media. They could easily recoup the cost of this by selling the list of stuff you bought to some ad people.
You think Netscape avoids bloated sites???? No way. With a non CSS compliant browser like netscape, you have to fill your pages with font tags and table formatting and other clutter, wheras a CSS compliant browser can take all this info from a single linked stylesheet. I realize that IE is not 100% compliant (on the PC anyway), but it is leaps and bounds ahead of netscape4.x!
Because Agent Pendrell is dead.
You end up with a show that has two distinct sides: "conspiracy" episodes, and the "x-file" episodes. I find the x-file episodes boring, because 1) they don't matter in the long-run, and 2) they are frequently silly/inane (witness that rediclous FPS episode, or the sad, sad, sad end-of-last-season episode involving Scully and Mulder being the subject of a Tea Leoni and Gary Shandling movie). There are a few exceptions (I think this season's baseball-loving alien was one of the show's best ever) but all in all, the conspiracy episodes are the only ones worth watching. Too bad those only air during sweeps, and then only a total of 4 or 5 this year.
Probably about half the x-files fans I know agree with you, and the other half likes the "x-file" episodes better, so it's good that they do both. More viewers that way. Me - I like both kinds, although lately the conspiracy episodes have seemed a bit forced.
-m.
One important point made: if a jury believes the law to be unjust or unjustly applied, they can reach a not guilty verdict even if they believe without a doubt that the person in question committed the act.
I think the term for that is "jury nullification."
I dunno - I bet Jack McCoy would go for Murder 2 on the grounds of "depraved indifference to human life." (Disclaimer - Like you, the bulk of my legal knowledge comes from Law & Order reruns.)
;-)
Wonder who would get jurisdiction - the state where the hacker/cracker lived or the state where the hacked computer lives? Or would it be federal? If Mir or the ISS were involved, jurisdiction could get real hairy. Oh well, we'll just have to wait for the Law & Order episode and all our complex legal questions will be answered
I actually met Dr. Joe Tsien, creator of the "doogie" mouse a few months ago. (Another neuroscience grad student and I invited him to give a seminar at our university.) Apparently, Daniel Keys read about Dr. Tsien's work (there was a lot of media hoop-la) so he called him up to ask him some technical questions. Turns out he was writing the last couple of chapters of the sequel to Flowers for Algernon when the story broke. A timely book, it seems.
-margaret
EXCUSE ME?!? I hope this was an attempt at sarcasm. I vote for whoever I damn well please. So does my mom. And I'm pretty sure that Mary Matalin doesn't vote for whoever James Carville tells her too.
Speaking of domain names, I stumbled upon this today. If you go to domaindirect.com and type in billbradley, it of course says that .com .net and .org are taken. If you click on each one, it does a whois search. (I was looking for an email address to send a friend's as yet unanswered complaint about their campaign mailing list's bad grammar and spelling, but that's another story.)
.net and .org say pretty much the same thing:
.org and .net?
Anyway, here is what you get for billbradley.com:
Registrant:
Bill Bradley for President (BILLBRADLEY-DOM)
395 Pleasant Valley Way
West Orange, NJ 07052
US
Domain Name: BILLBRADLEY.COM
Administrative Contact, Technical Contact, Zone Contact:
Gore, Al (LR1487) haxormad@HOTMAIL.COM
AlGore2000.com
2410 Charlotte Avenue
Nashville, 37203 37203
202.644.9658
Record last updated on 02-Feb-2000.
Record created on 03-Mar-1997.
Database last updated on 26-Feb-2000 12:34:27 EST.
Domain servers in listed order:
NS1.SHORE.NET 192.233.85.129
NS2.SHORE.NET 192.233.145.5
NS3.SHORE.NET 192.233.145.6
NS4.SHORE.NET 192.233.85.21
HOLY SMOKES! Does this mean that Al Gore bought billbradley.com in 1997 and then sold it to them? I don't know much about this type of thing, which is why I'm asking here. The entries for
Domain Name: BILLBRADLEY.NET
Administrative Contact:
Turlington, Ed (ET1357) edturlington@BILLBRADLEY.COM
The Office of Bill Bradley
1661 Page Mill Road
Palo Alto,, CA 94304
650-494-2554 (FAX) 650-494-1739
Technical Contact, Zone Contact:
Registrar, Domain (DR1432) shore-dns@SHORE.NET
Shore.Net
173 Oxford Street
Lynn, MA 01901
781-477-2000 (FAX) 781-593-6858
Record last updated on 05-May-1998.
Record created on 05-May-1998.
Database last updated on 27-Feb-2000 17:29:17 EST.
Domain servers in listed order:
NS1.SHORE.NET 192.233.85.129
NS3.SHORE.NET 192.233.145.6
Am I interpreting this corectly - the Gore people bought billbradley.com in 1997, then sometime before May 1998, the Bradley people bought it from them then also bought
-margaret
I used domaindirect.com to register my domain. It was $70 for 2 years, which after reading the other posts, I suppose is expensive.
Anyway, domaindirect is run by TUCOWS and I've had nothing but excellent service. If you don't have an IP address to give thenm they will set up a "coming soon" page for you, or you can have it forward to another page. You can also set it up so that your domain name stays in the browser address bar after it forwards. (I think they use an invisible frame or something.) You can edit the meta tags for the forwarding page too.
As far as email, you get 5 addresses to make up at your domain name. You can either specify a location to forward to, or else use POP mail to check them.
Hope this helps,
-margaret
Kary Mullis got some compensation - a rather large bonus from Cetus and a Nobel Prize. But no royalities from the patent. In interviews he's said that the powers that be at Cetus originally thought he was wasting his time on PCR, and he that he feels shafted by them. I'm not sure how much he had to do with Taq though - he left a few years before the Taq patent was applied for. (The original PCR process did not involve Taq.)
And just becasue Promega has a patent on Taq polymerase, it doesn't mean you can't make your own. My lab has a freezer full of Taq that we made. It's pretty simple - clone the gene, express it in E. Coli, purify the proteins, heat-kill the unwanted proteins, and viola - hundreds of thousands of dollars worth of Taq. As far as I know, as long as we don't try to sell it, this is perfectly legal.
There is an article about it in the latest issue of the alumni magazine from Johns Hopkins (my alma mater
I was going to submit it, but this guy beat me to it. Sounds very star-trekky, doesn't it?
-m.
I don't understand these posts which say that Mozilla, in its current state, is better than IE. Everytime I try Mozilla, there are pages which work fine in both IE and NS, but which Mozilla doesn't render correctly. And Mozilla inevitably crashes after I spend any time using it.
Maybe it has something to do with procesor speed? I've read that gecko's supposed to be really fast, but mozilla runs slow as molasses on my system. (I am stuck using a POS pentium 90 though.) By itself, however, viewer.exe runs at a decent speed, so maybe slower processors can't handle rendering the "chrome" and other extras...
But I'm just guessing. Any mozilla people out there?