Slashdot Mirror


Genetically Engineered "Smart" Mice

Lucius Lucanius writes "A smart gene that helps mice learn faster has been discovered. This follows recent discoveries about neuron generation in monkeys and the creation of doogie the smart mouse. Excitement abounds in the "smart pet" industry, but will it ever be applied to humans?"

240 comments

  1. Just what I need.... by Astralmind · · Score: 1

    I wonder if I could train a "smart" dog to have dinner ready for me when I get home?

  2. Will this help me frag at QII Arena? by cvd6262 · · Score: 2

    If I use a smart mouse, will I be better at Quake II Arena?

    --

    I'd rather have someone respond than be modded up.

  3. Time to buy flowers ..... by taniwha · · Score: 5

    for Algernon ...

    1. Re:Time to buy flowers ..... by taniwha · · Score: 1

      geez - who mod'd me down - have you never read Asimov's "Flowers for Algernon"? about amoung other things an intelligence enhanced lab-mouse

    2. Re:Time to buy flowers ..... by geekd · · Score: 1

      actually, I had to read it in grade school....

      one of the few "compulsory" reads that was actually any good.

      -geekd

    3. Re:Time to buy flowers ..... by John+Miles · · Score: 1

      FFA was by Daniel Keyes, if I remember right. Scary piece of work. Not off-topic at all, for those who've read it!

      --
      Dahlmann tightly grips the knife, which he may have no idea how to use, and steps out into the plain.
    4. Re:Time to buy flowers ..... by TBHiX · · Score: 3

      Too bad I'm out of mod points to bring this back up...

      It appears those responsible for the "Offtopic" label are unfamiliar with the play/movie Charly and Algernon, or Flowers for Algernon (I can't recall which was which.) For the record, An intellectually delayed young man (Charly) and a lab mouse (Algernon) are made supergeniuses of their respective species by a revolutionary new treatment. Charly has to come to terms with the changes this has wrought in his existence, and, later, with the threat that the experiement will have tragic side-effects. Very well done and quite thought-provoking.

      -TBHiX-

    5. Re:Time to buy flowers ..... by pawndog · · Score: 1

      Flowers for Algernon...

      Secret of NIHM...

      or

      Planet of the Apes

      take your pick. :)
      (The "smart pets" reminded me of one of the planet of the apes movies...)

      --
      [Posted from deep within the northen forests of North America, via TCP/IP tunneled over carrier pidgeon]
    6. Re:Time to buy flowers ..... by taniwha · · Score: 1

      yeah you're right serves me right for doing an altavista search, seeing "Asimov's Homepage" show up first and not actually look at it :-)

    7. Re:Time to buy flowers ..... by lar · · Score: 1
      You guys all read the novella, right? Because the novella (which is about 60 pages) is a whole lot better than the full length novel.

      If you've never read the novella and can get ahold of it, I highly recommend reading it. My eigth grade teacher had us read it on photocopied packets instead of from the actual book it was in, so I can never seem to find it though.

      ==

      --
      ==
      I don't know exactly what that means, but I'm sure it means something....
    8. Re:Time to buy flowers ..... by Dirtside · · Score: 3

      The movie was "Charly," from 1968, starring Cliff Robertson as the retarded young man who gets turned into a genius (Robertson won a Best Actor Oscar for his performance). The original written novella (60 pages or so) was entitled, "Flowers for Algernon" by Daniel Keyes.

      --
      "Destroy science and religion. Science would re-emerge exactly the same; but not religion." - Penn Jillette, paraphrased
    9. Re:Time to buy flowers ..... by PurpleBob · · Score: 2

      Lighten up. Do you even know what "Flowers for Algernon" is? Without looking at the other responses?
      --
      No more e-mail address game - see my user info. Time for revenge.

      --
      Win dain a lotica, en vai tu ri silota
    10. Re:Time to buy flowers ..... by Phil-14 · · Score: 1

      Pinky! They're too distracted thinking about Flowers for Algernon and the Secret of NIMH! This could be our chance to sieze control!


      --
      (currently testing something about signatures here)
    11. Re:Time to buy flowers ..... by TBHiX · · Score: 1

      Beleive it or not, there was also a stage play. A musical, if I recall correctly, though a passable one once you get passed the idea of it.

      -TBHiX-

    12. Re:Time to buy flowers ..... by Bush+Pig · · Score: 1

      Glad I'm not the only person old enough to have read it ... interestingly, I saw a new reprint on sale the other day.

      --
      What a long, strange trip it's been.
    13. Re:Time to buy flowers ..... by margaret · · Score: 1

      I actually met Dr. Joe Tsien, creator of the "doogie" mouse a few months ago. (Another neuroscience grad student and I invited him to give a seminar at our university.) Apparently, Daniel Keys read about Dr. Tsien's work (there was a lot of media hoop-la) so he called him up to ask him some technical questions. Turns out he was writing the last couple of chapters of the sequel to Flowers for Algernon when the story broke. A timely book, it seems.

      -margaret

  4. Smart humans. by wowbagger · · Score: 4

    Personally, I can't wait. Maybe we can get smart humans, instead of the dumb variety we have now. (want proof? Read at 0).

    1. Re:Smart humans. by Anonymous Coward · · Score: 2

      Want to see really dumb humans? Read at 4 or 5.

    2. Re:Smart humans. by CleverNickName · · Score: 1
      Maybe we can get smart humans, instead of the dumb variety we have now

      You realize that this will never happen if the studios have their way. If people get smart, there won't be anyone left to watch the WB.

  5. Why me? by [hk]doogie · · Score: 1

    I guess i'm the hunter/killer doogie mouse now.

  6. Forget the smart gene... by levendis · · Score: 2

    Lets find the Karma gene! I bet we could extract it from Signal 11. And while we're at it, lets eliminate the Troll and Flamebait genes.

    --
    ---- I made the Kessel Run in under 11 parsecs.
    1. Re:Forget the smart gene... by Signal+11 · · Score: 1

      Sorry dude, I got a patent on all three of them. Good luck!

  7. Well... by Rombuu · · Score: 2

    Excitement abounds in the "smart pet" industry, but will it ever be applied to humans?"

    Who would want a smart human as a pet?

    --

    DrLunch.com The site that tells you what's for lunch!
  8. "Smart" Mice? by Money__ · · Score: 1

    You mean my peecee mouse will know to click on porn before I do? ;)
    ___

    1. Re:"Smart" Mice? by Cybersonic · · Score: 1

      damn! you MADE me click on that link!

      --
      Cybie! aka Ralph Bonnell
    2. Re:"Smart" Mice? by Money__ · · Score: 1
      Re:damn! you MADE me click on that link!

      Try this one
      ___

    3. Re:"Smart" Mice? by Cybersonic · · Score: 1

      what is that supposed to do? i dont have one of those C: drives...;)

      heh, doesnt do much on a Linux box

      --
      Cybie! aka Ralph Bonnell
  9. One word... by levendis · · Score: 3

    Intellimouse

    --
    ---- I made the Kessel Run in under 11 parsecs.
  10. from the hall of Duh. by deander2 · · Score: 5

    Come on guys, do we really NEED smarter mice? What happens when they "learn" what a mouse trap is? What happens when they "learn" to open the fridge? Come on, THINK before you act people!

    :-)

    1. Re:from the hall of Duh. by Kronovohr · · Score: 2

      ...OR, try to take over the world...

      "What're we gonna do tonight, Brain?"
      "Same thing we do every night, Pinkie! Try to take over the world!"

    2. Re:from the hall of Duh. by Goldberg's+Pants · · Score: 1
      What happens when they "learn" what a mouse trap is?

      We build a better mousetrap.

      (Desperately hopes the reference isn't lost.)

      ---

    3. Re:from the hall of Duh. by Chiasmus_ · · Score: 2

      That's actually one of the concerns I have about our current ethical paradigm, wherere screwing around with the genetics of animals is "research", and screwing around with the genetics of people is "playing God".

      People have made the "playing God" argument about all sorts of technologies. Airplanes were "playing God" - men shouldn't be able to fly. The Polio vaccine was "playing God" - men shouldn't be able to prevent disease.

      The only problem is, when we "play God", we seem to do a better job than God.

      And if we start going around genetically enhancing every other species we can find, eventually, we're going to make them a little too good. I'm not talking about doomsday scenarios, like that stupid-ass movie with the "smart sharks" - but don't you think that a bunch of smart mice, or houseflies, or cats, could get a little annoying?

      Personally, I do NOT want my hamster to be able to figure out how to open the fridge - or, for that matter, how to log on and post flamebait about how much Signal 11 sucks.

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
    4. Re:from the hall of Duh. by Ravagin · · Score: 1

      Build a better mousetrap, and the world will flock to your door.
      Build a better mouse, and the peasants will break out the torches and pitchforks.
      ===
      -J

      --

      Karma: T-rexcellent.

    5. Re:from the hall of Duh. by DrEldarion · · Score: 1

      I used to have pet mice, and they were too smart as it was. They would always manage to find a way out of their cage, no matter how hard we tried to prevent it.

      -- Dr. Eldarion --

    6. Re:from the hall of Duh. by eggnet · · Score: 1

      I used to have pet mice, and they were too smart as it was. They would always manage to find a way out of their cage, no matter how hard we tried to prevent it.

      Let's see. This could be explained by mutant hyperintelligent mice, or...

    7. Re:from the hall of Duh. by Tarsh · · Score: 1

      heh, they obviously haven't seen Deep Blue Sea. The made the sharks smarter and look what happened.

      --

      EOT
    8. Re:from the hall of Duh. by Beatles · · Score: 1

      I don't know about airplanes, they seem alright, as they cause more deaths, but we definitly need to stop saving so many people. Whatever happened to natural selection? Sure, a select few die, but we making it increasingly hard for the morons to be seeded out. The decline of the human race will be due to our insane need to save everyone. Evolution will stop, and De-evolution will begin. In a few generations, all people will basically be stupider versions of apes.

      Fuck humanity...

    9. Re:from the hall of Duh. by Beatles · · Score: 1

      This comment being in reply to the polio vacine remark. Of course, I'm also not in support of genetic manipulation...

    10. Re:from the hall of Duh. by Punto · · Score: 1
      Or maybe the inteligent mouse and the inteligent cat flood the living room and turn the water into ice, and start iceskating.

      --

      --

      --
      Stay tuned for some shock and awe coming right up after this messages!

    11. Re:from the hall of Duh. by Happy+Monkey · · Score: 1

      Cool. I need a new path to my door.
      ___

      --
      __
      Do ya feel happy-go-lucky, punk?
    12. Re:from the hall of Duh. by vanix · · Score: 1
      I'm not talking about doomsday scenarios, like that stupid-ass movie with the "smart sharks" - but don't you think that a bunch of smart mice, or houseflies, or cats, could get a little annoying?
      I think you're vastly overestimating how smart animals can really be made, even if we fully understood intelligence and learning. All they were really able to do was give the mice slightly better memories by making their brains produce higher levels of a particular neurotransmitter which is associated with memory formation.
      --
      "Government is a disease masquerading as its own cure." --Robert LeFevre
  11. Gattaca has arrived by Dusabre · · Score: 1

    Well, if Gattaca is round the corner, I better start saving up for college *and* genetic engineering for my kids. At 24, having finished university this year. Sigh. But on the bright side its a good excuse for putting off fatherhood, "honey if we wait till next year, we can have an even smarter kid!"

    1. Re:Gattaca has arrived by mrzaph0d · · Score: 1

      yeah but if you wait till next year, the manufacturers will just promise you a smarter kid six months from then...the prices will keep dropping, and new levels of intelligence would be introduced each year...it'd never be a really good time to by. i'm gonna stick with my 650MHz kid...

      "Leave the gun, take the canoli."

      --
      this is just a placeholder till i send back my real sig from the future.
  12. And just what humans would we use for testing? by 10.0.0.1 · · Score: 1

    I would think the folks at PETA would be the first in line for testing. That would kill two birds with one stone.* * This is an "expression" and is not intended to suggest that it is okay to kill birds.

    --
    forth ?love if honk then
  13. Creepy implications for the environment by abulafia · · Score: 1

    If someone does start marketing smart pets, we'll probably see all sorts of disruptions in nature. Smarter mice would quickly outcompete the dumber, unmodified ones. How well would they do against unmodified cats?

    --
    I forget what 8 was for.
  14. Goodbye /. my old friend... by Anonymous Coward · · Score: 1

    A smart gene does not bode well for its continued existence. -- Feel free to mod to -1 troll; I dont care, my pet dog can probably beat you at checkers anyway.

  15. Beware! by suwalski · · Score: 2

    It's Pinky, it's Pinky and the Brain, Brain, Brain, Brain....

  16. Human Evolution by DranoK · · Score: 4

    Please, I beg of you, do not moderate this down or reply in flame because you disagree! I'm only trying to make a point (that you may or not believe in) for the sake of discussion.

    Evolution has held before a process of survival of the fittest. OK. This is very over-simplified, but let's just leave it at that. We can assume that there are minor differences in every creature, and those differences which prove beneficial tend to be passed on, thus evolving the species. I know we now know that there are conditions that can alter the rate of evolution, but again, for the sake of discussion, let's keep it simple.

    The problem that I've always seen is that humans have stopped evolving. At least according to this scheme. Sure, we keep attaining more knowlege, but for the most part the biological (and this includes mental) aspect of humanity is not changing (at least in no way that is caused by the strictest sense of evolution). This is because we no longer abide by "survival of the fittest".

    Sure, just because someone is smarter / stronger / etc than most gives him/her a huge advantage in life, but doesn't necessarily affect the outcome of survival. With some exceptions, no longer do the fittest survive only, but all do. This means that weak genes are just as likely to be passed along as strong ones. Evolution, for the most part, no longer applies.

    Have we reached the stage where we need to evolve ourselves? Where we are in control of evolution? It's a scary thought. Granted, this article only hints of what may be possible in the future, but it's a concept that is relatively new and frighteningly, very feasable. The ability to modify genes in an unborn embryo.

    Isn't this controlling the specie's evolution? No matter how many laws the nation or world passes, if the technology exists it will be used. There is not, however, any way to stop the progress.

    Personally, I don't think the question is if we ever are able to control our own evolution, how to we stop it, but, when we are able to control our own evolution, how will we mold it?

    Something to think about.

    Peace,
    DranoK


    That is not dead which can eternal lie, and with strange eons even death may die.

    --

    Shh! Nobody knows I'm gay!
    1. Re:Human Evolution by TrumpetPower! · · Score: 3

      First, evolution takes place on a scale of tens of thousands of years. Humans have not been recording their observations of the world long enough to see the changes in ourselves or anything else around us.

      Second, environment is critical to the definition of "fittest." Bill Gates wouldn't last a week in the savannas where australopithecine thrived; none of them would ever be able to live in a human city (except as an exhibit or experiment).

      I personally doubt that bioengineering will do much in the way of human evolution. Rather, I expect either computer-based life, a blend of computers and humans, or corporate/political conglomerates to be the next stage. That is, of course, assuming that we don't off ourselves first. We still have too many problems with race for "bio-enhanced" people to be acceptable to society.

      b&

      --
      All but God can prove this sentence true.
    2. Re:Human Evolution by ZiGGyKAoS · · Score: 1

      This is obvsouly where we are going and have to in order to survive as a species. i am glad that there is another smart person in the world that relizes that when we support a person with a disability that we are dirtying our own gene pool yes it sounds cruel. but get over it.

      our options are as follows,
      if we are to survive as a species we must
      A. only allow "healthy" humans to be born
      B. evolve ourselves.

      i prefer B.

    3. Re:Human Evolution by kurowski · · Score: 3
      The problem that I've always seen is that humans have stopped evolving.

      Please back up this statement with some facts.

      I don't see that humans have stopped evolving. Sure, we haven't seen any significant changes in the human species during the course of recorded history, but we also haven't seen any significant changes in elephants, whales, lions, et cetera.

      The times when evolution will be most noticeable will be during times of scarcity. Otherwise, there is no natural selection occuring because everyone is fit to survive.

      Wait a few centuries for overpopulation to really kick in, then you'll notice large numbers of human beings dying out. You'll also notice selection kicking in. However, keep in mind that physical traits aren't going to be the only factor in selection. Natural selection will probably be most apparent between different cultures due to sociobiological effects. Simply put, some behaviors among groups will make them likely to out-compete other groups of people.

    4. Re:Human Evolution by marick · · Score: 1
      The problem that I've always seen is that humans have stopped evolving. At least according to this scheme. Sure, we keep attaining more knowlege, but for the most part the biological (and this includes mental) aspect of humanity is not changing (at least in no way that is caused by the strictest sense of evolution). This is because we no longer abide by "survival of the fittest".

      Yes, what you are saying is accurate in the West, but I'm not so sure it applies in places where (for example) overcrowding has resulted in lower birthrates and the like. For example, in China (where multiple-child families are disallowed), it is possible that the ability to sire male children is selected for, since so many female embryos are aborted.

      Further, in places where drought and famine are serious issues, it is conceivable that the ability to survive with less water/food is being selected for - i.e. perhaps the rate of twins is dropping.

      The main problem with any of these kind of discussions is that evolution of any kind develops over millenia, not years and decades.

    5. Re:Human Evolution by Chiasmus_ · · Score: 2

      Fortunately, I've already foiled you with my strategy of "sleeping with ugly girls"

      It's not always pleasant, but, hey, I'm a professional coder.

      Speaking of which, can we forego the "smart" gene and focus on "attractive" genes? I think the human species tends to be smart enough for my taste. I'd rather be around hot chicks that I could trick into sleeping with me than hideously ugly chicks who could beat me at chess.

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
    6. Re:Human Evolution by zeck · · Score: 2

      i am glad that there is another smart person in the world that relizes that when we support a person with a disability that we are dirtying our own gene pool yes it sounds cruel. but get over it.

      This is a gross oversimplification of a complex problem. Allowing a disabled person to survice is not dirtying the gene pool. Allowing a disabled person to pass on his/her genes may be detrimental to the gene pool, depending on whether the genes causing the disability are actually passed on and whether the total outweighs the negative aspect of the genes. For instance, a man with a poor sense of smell but an extremely advanced immune system could be extremely beneficial to the species. The classic real world example is Stephen Hawking, who a century ago would have been rotting in a hospital if not already dead. Certainly controlled evolution is necessary to secure the future of life, but there's a lot more to it than your oversimplification.

      For one thing, only allow "healthy" humans to be born and evolve ourselves are not adequate descriptions. Only allowing conformist genes to enter the genepool would be a form of evolution, so (A) is really just a subset of (B). I think that what you really meant to say is that we are faced with a choice between not allowing people with genetic defects to reproduce and allowing them to reproduce but working to correct their defects.

    7. Re:Human Evolution by JTB · · Score: 2
      First, evolution takes place on a scale of tens of thousands of years. Humans have not been recording their observations of the world long enough to see the changes in ourselves or anything else around us.

      True. Nonetheless, in the last few hundred years, we have constructed roadblocks to natural selection in the form of modern medicine.

      Are you genetically predisposed to:

      bad eyesight? No worries, we've got laser vision correction!

      obesity? Don't sweat it, you won't have to chase down your dinner, just pull through to the next window!

      impotence? VIAGRA!

      anything else that makes you "weaker" and less likely to propogate your genes in a natural state? Bah, we'll build a designer drug! Have kids! Spread those genes down through the generations!

      No worries! We don't enough recorded history to show that we're slowing evolution! Let the weak live!

      Make sense?

      -JTB

    8. Re:Human Evolution by lukel · · Score: 2
      The problem that I've always seen is that humans have stopped evolving.

      How is it a problem? First of all, why should we want to evolve. Single celled organisms are the most successful in terms of adaptation to different environments but I have no desire for my offspring to be single celled. Second, if it's the survival of the human race you are concerned about, then isn't your claim that that the human race is not evolving an good thing, i.e. we are not evolving because we are so good at surviving in our environment.

      This is because we no longer abide by "survival of the fittest".

      It's not survival that's important. Maybe, in the developed world at least, everyone survives to adulthood. But this is not enough, not only must you survive, you must find a mate and successfully rear offspring. It is probable that better looking people and those with better social skills are better at finding mates so more likely to pass on their genes, and those who love children rear them better and have bigger families, so are more likely to pass on their genes.

      weak genes are just as likely to be passed along as strong ones

      This seems a bit muddled. If two genes are equally likely to be passed on, surely they must be equally strong/weak. Perhaps you have some goal other than survival, but then its not evolution in the biological sense and we have never been heading for it except by chance.

      Please, I beg of you, do not ... reply in flame because you disagree! I'm only trying to make a point (that you may or not believe in) for the sake of discussion.

      Well, this is intended as discussion, not flame. Please take it as such!

    9. Re:Human Evolution by Garin · · Score: 1

      In addition, the -vast- majority of the world does not live as we do.

      To a first-order approximation, nobody on earth has ever: seen the internet, been vaccinated, visited a doctor, etc. Sure, we slap glasses on those with bad eyes (like me) but if you're born in rural India or Africa, you'll never see them, let alone get some yourself.

      Strict biological evolution won't be driven by us, it will be driven by them. The Africans are facing a gigantic AIDS crisis -- guess where the seeds of adaptation to AIDS are being sown? In addition, true evoltion isn't always as simple as Darwinian natural selection. A lot of it has to do with pure random chance. Sure, mammals took over from dinosaurs, but what if the earth hadn't been hit by a big bloody rock?

      --
      In any field, find the strangest thing and then explore it. -John Archibald Wheeler
    10. Re:Human Evolution by bgalehouse · · Score: 1
      Have we reached the stage where we need to evolve ourselves? Where we are in control of evolution? It's a scary thought. Granted, this article only hints of what may be possible in the future, but it's a concept that is relatively new and frighteningly, very feasable. The ability to modify genes in an unborn embryo.

      We are already in control of our evolution. We don't allways admit it, but we've been thinking about where kids come from for a long time. We aren't as ruthless as we are when engineering crops through natural selection, but the principle applies. And we've certainly made serious changes to certian other species. (where is corn 'native' to? how about cows?)

      Anyway you look at it, memes evolve much faster than genes.

      Also, evolution of both memes and genes tends to be punctuated, not continuous. Paradigm shifts and extinction events are cut from the same cloth. We are what we think. We think what we learn. We learn memes.

    11. Re:Human Evolution by TwoSevenOneEight · · Score: 1
      Keeping your genes in the pool requires not just that you survive, but also that you reproduce. The factors that determine how organisms choose their mates are powerful drivers of how a species evolves.

      For example, male peacocks have tails that are a pretty strong impediment to survival. A bird has to consume a lot of resources to grow the thing, and I would imagine a huge tail is tough to lug around through the woods. Suppose for whatever reason that some set of female birds develops a preference for males with large tails. Those males get to reproduce more, so more large tail genes end up in the pool. Since females with the preference mate with the large-tailed males, they are likely to pass on this preference, since their male progeny produce lots of offspring. The result is a positive feedback loop, and you end up with animals having all sorts of strange features that don't necessarily have much to do with survival. (It's currently believed that the tail is a signalling device that gives female birds an idea of how healthy the male is, so the tail isn't a complete waste)

      The point is, although economic prosperity and health care advances have reduced the impact of a lot of the forces of natural selection in many parts of the world, sexual selection will continue to drive human evolution. The Red Queen: Sex and the Evolution of Human Nature by Matt Ridley has a fascinating discussion on the subject.

      2.718

    12. Re:Human Evolution by shiva-dow · · Score: 1

      Let's look at this as a biological programming problem.

      If certain very large and powerful software houses can not produce an operating system without bugs, even when they have the source code for all the tools that are used in the production of that operating system, how can anyone expect a positive outcome from patching an operating system which is orders of magnitude more complex and for which no source is available.

      It was working alone and did't have time to document the code for the biological elements. The whole project had to be completed in six days.

      Are you feeling lucky, punk?

    13. Re:Human Evolution by jonathanclark · · Score: 2

      Have we reached the stage where we need to evolve ourselves? Where we are in control of evolution?

      I was thinking of this last night and I came to the conclusion that we already control our evolution. Fetuses are routinely tested for a host of problems before they are born. Many parents will chose to not have the child if it doesn't look like it will fare well. If that isn't selection what is?

      Also in China and countries where the government only allows parents to have one child parents regularly pre-select male children. I really have no clue why this is, but I suspect it is because: a> the family name is carried down through the male. b> the male child has a better chance at a higher paying job the way the world is structured today. While this may not seem like evolution I think it is. If there are 70% males and 30% females then natural selection in the male population is going to occur more rapidly.

    14. Re:Human Evolution by chemgoddess · · Score: 1

      Actually, AC is correct. Evolution over short periods of time is a valid theory (punctuated equilibrium). Besides, since evolution is defined as the change in gene ratios within a population, then those one generation pandemics are definitely a selective force.

      As for weak genes being selected for, who's to say what will be 'weak' in the future. It's a well known fact that the 'weak' gene for sickle cell anemia is protection against malaria, and it's highly possible that cystic fibrosis is common in Europeans because it offered protection from the plague.

      Maybe the defective genes of today will be an advantage in the future.

      --
      It's your own fault, you must have gotten me started.
    15. Re:Human Evolution by Bodrius · · Score: 1


      >The problem that I've always seen is that humans
      >have stopped evolving. At least according to
      >this scheme. Sure, we keep attaining more
      >knowlege, but for the most part the biological
      >(and this includes mental) aspect of humanity is
      >not changing (at least in no way that is caused
      >by the strictest sense of evolution).

      Two things:
      - Evolution is slow. Humankind is ridiculously young as a species; I would not expect radical changes for a while, and there are small changes.
      - We do keep evolving; "survival of the fittest" is not restricted to anathomical means. A species is a whole containing the body, the mental tools and the social structures it has evolved... for humans that includes teachable skills.

      Since techno-social change is faster and more adaptive, it will obviously be prefered by evolution to biological change.

      >Sure, just because someone is smarter / stronger
      >/ etc than most gives him/her a huge advantage
      >in life, but doesn't necessarily affect the
      >outcome of survival

      Nor does it necessarily affect the survival of an animal "in the wild". If it were a matter only of survival and "not passing the weak genes", there would be no monkeys, reptiles, or other branches of species that evolved into something else at one time or another.

      >Personally, I don't think the question is if we
      >ever are able to control our own evolution, how
      >to we stop it, but, when we are able to control
      >our own evolution, how will we mold it?

      In the same way evolution always has: as necessity or convenience dictates. It works.
      And ironically, it puts our "guidance" in perspective.

      Bodrius

      --
      Freedom is the freedom to say 2+2=4, everything else follows...
    16. Re:Human Evolution by ai731 · · Score: 1

      "The problem that I've always seen is that humans have stopped evolving."

      Please back up this statement with some facts.

      I'm not sure what you mean by facts; but I would back up the statement "Humans have stopped Evolving" by saying "the ability to survive the physical stresses of the environment is no longer the primary criterion for likelyhood to pass genetic material to offspring."

      For instance, a significantly premature baby will now survive if it is born where successful medical intervention is possible.

      I'm not saying modern medicine is bad, I am saying that we now use choice (do you want a boy or a girl), laws (200$ fine for not wearing a seatbelt of a motorcycle helmet) and medical technology of all kinds to decide who lives and who dies rather than leaving each individual to battle it out with their environment on their own, like the PCB-contaminated salmon and Brown bears still have to do.

      The salmon and the bears are still evolving. We are engaging in selection based on other criterion.

      ai731

      --

      --
      "I use the words you taught me. If they don't mean anything any more, teach me others. Or let me be silent"
    17. Re:Human Evolution by Zanth_ · · Score: 1

      naturally, humans are designed to have flaws, even the "fittest" first fittest should be clarified to mean reproductive capability, and hence once that time in life has passed, latent genes which are malignant or at least disease causing, will still appear in the progeny. Our evolution has not stopped if evolution is actually a case to be discussed, rather we, using our medical technology have slowed it to a turtle's pace. Remeber mdrs and other naturally occuring resisters to cancer drugs. These proteins actually help us to die! We ourselves are pushing us to the limits but our bodies are still fighting to remain in union with mother nature and have the human race at large die at a reasonable age. We may extend our live cycle, but not indefinitely, we are evolving, our bodies are evolving ways to die.

    18. Re:Human Evolution by Falcula · · Score: 1

      The problem is we are to compassionate and/or willing to meddle. Think of it, if somebody isn't smart enough to wear a seatbelt when driving or a life jacket when waterskiing, then we have to make a law to protect the stupid people from themselves. Now the timid people are protected and able to propagate efficiently.

      By a similar train of thought, The laws that prevent the Creative people from experementing and therefore draw more attention to themselves and attract suitable mates (DMCA, Local ordinances against building spaceships in the back yard, etc.) make the propigation of genius more difficult.

      The only people weeded out are the Creative stupid people (ala darwin awards) and you have to know some of these people are responsible for the creation of new laws to protect other similarly stupid people.

      From a gene pool standpoint we are only shooting ourselves in the foot...

    19. Re:Human Evolution by Dan+O'Shea · · Score: 1

      There you go thinking like a westerner again! =)

      Males are preferred much in the same way as males have always been preferred in all poor agricultural environments, not that ALL of China is like that mind you, but ALOT of it is, which sex is better at providing additional help at gathering the resources necessary for me and my family to live, a male or a female? Males are preferred for their ability to work and the fact that daughters are viewed in this context as a drain on resources with which little or no benefit is derived. As far as carrying on the family name is concerned I am unsure as to how strong a person of chinese origin cares about this.

      Many a night is spent with my chinese girlfriend discussing our cultural differences in how they relate to why her parents originally harbored much dislike for me. One which I had never heard before coincidentally had to do with the seemingly overt hairyness of my body (I'm irish-basque) Hairyness is viewed as a trait of lazyness in her parents cultural upbrining and hence they thought their daughter was getting involved with a lazy bum. Further inspection on their part has since allayed their fears, for as we all know irish people have had quite an arduous existence often having to work very hard in order to survive (hehehehe.) I suppose that is why we are genetically superior (just KIDDING!!!)

      And Basque people are all ill-tempered revolutionaries, which explains my love for UNIX and Linux, it opposes the mainstream computing culture!!!!! hee hee hee....

    20. Re:Human Evolution by jonathanclark · · Score: 1

      Males are preferred much in the same way as males have always been preferred in all poor agricultural environments, not that ALL of China is like that mind you, but ALOT of it is

      I considered this, however the process of selecting male sperm from female sperm is not something that comes cheaply to a poor farmer. For this reason, it only occurs in middle/upper class families - and thus not for the reasons you suggested. Not to say that lower class families don't abort or leave female children to die. But that is a different story.

    21. Re:Human Evolution by luke_ · · Score: 1

      There are a few misconceptions about evolution that I think need to be cleared up:

      First, one can think of evolution as being dependent on a large percentage of the population dying. On earth, this is still true. 40,000 children die every day of preventable illnesses. 16,000 people are infected with HIV every day (which will undoubtedly cause selected populations of people with disproportionate levels of mutations in the CCR5 chemokine receptor that renders them resistant to infection through mucosal membranes). But maybe a more important thing is the idea of unborn children. In the end, the groups having the most children will win out. Evolution still occurs, just not by the same factors as 15,000 years ago.

      Another thing to remember is that humans evolve/have evolved as a group, not as individuals. This is because homo sapiens is a pack animal, like ants or wolves. Long fangs and aggressiveness might help out a bear in the wild, but would probably just have gotten a homo erectus clubbed to death by the rest of the group. Traits like kindness and self-sacrifice (or propensity for religious belief) were selected for because they promoted the survival of the race as a whole. So in this sense, "social evolution" is nothing new.

      A third thing, men's attraction to large breasts is based on breasts being one of the things that differentiates fertile women from prepubescent girls and other men, not women with large breasts from women with small breasts, as there is no serious correlation of breast size with ability to nourish a child (at least not a more significant correlation than there would be with other obvious markers of health). This is a subtle distinction, but an important one, I think.

    22. Re:Human Evolution by Dan+O'Shea · · Score: 1

      There you go thinking like a westerner...it isn't that they select sperm, they simply concieve a child and then terminate based upon the sex of the foetus. I know a chinese doctor who has performed this in the past. That person now lives in the us and programs for a living.

    23. Re:Human Evolution by warpath · · Score: 1

      "Common Sense Laws" really are, in effect, working against Natural Selection.

      However, I wouldn't say that we are no longer evolving. Most of the changes just aren't so physically obvious. I'd guess faster mental processes, better multitasking, etc. NOTE: I have no facts to back this statement up... I'm just guessing. :)

      w

      \//

    24. Re:Human Evolution by Weezul · · Score: 2

      You do not have any evidence to back up the statment that humans have stopped evolving. First, it happens that we are not liviing in a spurt of bioogical evolution. I don't think we totally understand the factors that control the spurts of biological evolution, so it's pretty premature to make any judgements. I know someone mentioned that scarcaty and overpopulation have something to do with it, but it could be other things like society percolating into subcultures too.

      Second, our intelegecne and understanding of the world *is* one of the ways we evolve. The development of biotechnology just gives one more way for this software evoltion to influence the hardware evolution.

      Third, humans controlling their own evolution is not scary. The human modifications which fuck up will not survive. Humans and/or natural selection will undo our screwups.

      Actualy, human control over human evolution could be a wonderful thing for exactly all the reasons that the ludites fear it (like new viruses). If human evolution divurges into multiple species then we may become more immune to these new viruses.

      Really, the one hting we should do is pass laws requiring human genetic modifications to be "open source," i.e. no patents on modifications to humans. This would prevent the corperations from controlling all the technology and would allow human evolution to divurge.

      --
      The Christian religion has been and still is the principal enemy of moral progress in the world. -- Bertrand Russell
    25. Re:Human Evolution by ZiGGyKAoS · · Score: 1

      Thank you, you understand.

      sorry for causing all the commotion.. :]

    26. Re:Human Evolution by gad_zuki! · · Score: 2

      Human evolution has been dead since the germ theory. Society subscribes to a higher ethic than just fight, fuck, and die. If natural selection was the one and only way to be evolved than a large brain at a certain point becomes a liability. I'd say get used to it, but considering your a human, you've had a life of socialization with all sorts of pampering and know exactly what I'm talking about.

  17. Search and destroy mouse... by Antipop · · Score: 1

    I wonder if we can train it to go and search and destroy missions? "Quick Intellimouse! Eliminate the neighbors and bring their caffeine to me!" =).
    -Antipop

    1. Re:Search and destroy mouse... by theseum · · Score: 1

      I think Bill Gates's intellimouse already does that.

  18. Hello Jonathon Frisby! by biznatch · · Score: 1

    Secret of NIMH, probably on my favorite movies as a kid. And now it's all possible...

    Interesting fact from that movie, Shannen Doherty did the voice of the little mouse Teresa.

    1. Re:Hello Jonathon Frisby! by CleverNickName · · Score: 1
      Interesting fact from that movie, Shannen Doherty did the voice of the little mouse Teresa.

      Wil Wheaton did the voice of Martin, one of the other Frisby mice, too.

    2. Re:Hello Jonathon Frisby! by danperkins · · Score: 1

      I read Mrs. Frisby and the Rats of NIMH in 5th grade. Nice book, spooky. It raises the question, if they make these mice too smart will the be able to escape and form complex tool weilding societies under rose bushes?

  19. Old news by blakestah · · Score: 3

    Anyone else notice how OLD all of this news is ??

    We read these papers in journal club last FALL !!

    Yet Hemos is posting it now. Hmmmmmmmmmmmmm.

    1. Re:Old news by Kefabi · · Score: 1

      Hey, well maybe YOUR the one with the old news. If you heard about it so long ago, why didn't you post it? The Slashdot team can only put up news stories as fast as they hear them. If no one submits the latest news, then the latest news doesn't get posted. Blame all the trolls on slashdot, not Hemos!

  20. In Humans? by PopeAlien · · Score: 1

    In tests, the "Doogie" mice significantly outperformed genetically unmodified mice in such tasks as running mazes, recognizing objects in their environment, and solving such problems as how to get themselves out of a pool of water and up onto a pedestal.

    When I haven't been drinking heavily, I can allready do all these tasks to a moderate degree...Bring on the wings and gills! Lets get Jiggy with this genetic engineering!

  21. Design a kid by Dusabre · · Score: 1

    For now I'll try out designing my child here

    1. Re:Design a kid by Chiasmus_ · · Score: 1

      Does anyone else hear a helicopter?

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
  22. Well well well.. by hhg · · Score: 1

    I'd love a smart me!

  23. Rats of Nihm.. by KlTheKiten · · Score: 1

    Am I the only one reminded of the book "The Rats of Nihm" which Disney later destroyed with the movie "The Secret of Nihm"?

    Basically the story of some Lab Rats and the widow and children of a Lab Mouse all of whom could read and reason beyond normal animals... (they even 'borrowed' electricity from the local farm for their own use.)

    Ahhh... the great days of childhood fantasies... eirie how they may come true...

    --

    ...some days you're the dog, some days you're the hydrant...
    1. Re:Rats of Nihm.. by BRock97 · · Score: 1

      Uhm, actually, it was a Don Bluth film, not Disney. Just FYI.

      Bryan R.

      --

      Bryan R.
      The price of freedom is eternal vigilance, or $12.50 as seen on eBay.....
  24. There must be some kind of drawback.. by CaptainSuperBoy · · Score: 2
    Reading this makes me think of what we've learned from evolution. If having this gene were better for the mice in the long run, wouldn't they already have evolved it? It's like, survival of the fittest, man.. I think nature has proven to us that in matters like this, it knows better than us. I really don't think any human can foresee the consequences of flipping around genes like this.

    And what would the consequences be if we were to take this discovery and apply it to humans? Why couldn't something like the movie Lawnmower Man happen (of course on a smaller scale)? We need to think long and hard before putting these types of discoveries to use.. we need to ask ourselves why these changes haven't evolved by themselves, in the same way they've been doing for millions of years.

    --

    1. Re:There must be some kind of drawback.. by Cinquero · · Score: 2

      It hasn't occurred because intelligence was never (and is not!) such an important factor for evolution or survival.

    2. Re:There must be some kind of drawback.. by gunner800 · · Score: 2
      OK, time for a quick refresher on Natural Selection. Evolution does NOT mean that a species will develop the best possible traits. It just means that, over a sufficiently long period of time (generations), good traits tend to persist more than bad traits.

      Good traits being those that make it more likely to pass on genes, bad traits being those that make it less likely.

      There are no guarantees, especially for some specific trait. It's like trying to guess lottery numbers. Something will happen, but you can't really predict what.


      My mom is not a Karma whore!

    3. Re:There must be some kind of drawback.. by vanix · · Score: 1

      Evolution produces "good enough" solutions, not optimal ones.

      --
      "Government is a disease masquerading as its own cure." --Robert LeFevre
  25. Smarter Mice by hypergeek · · Score: 5

    Are you pondering what I'm pondering, Pinky?

    --
    Stay up hacking each weekend. Sleep is for the week.
    1. Re:Smarter Mice by mduell · · Score: 1

      I think so Brain, but if I do switch from Windows to Linux, will I have more uptime?

      Mark Duell

    2. Re:Smarter Mice by mduell · · Score: 1

      Hey man, i dont use linux and i never will. (Or at least not until its as easy as DOS) But i know id be moderated to -999 if i said linux to windows increaces uptime so i put it the other way around. MS rules!

      Mark Duell

    3. Re:Smarter Mice by ajdavis · · Score: 1

      Of course, this is just one more ploy by the mice--3-dimensional incarnations of superintelligent hyperdimensional aliens--to make us think that it is we who are experimenting on them, and not vice versa. =)


  26. Almost certainly scientists are experimenting by anticypher · · Score: 2

    You can bet genetic scientists are looking at experimenting with this gene on humans.

    If similar genes are found in the human genome, then there will be a lot of clandestine experimentation to find the "higher intelligence" switch. Once there is sufficient scientific proof of children with IQ>150 on a regular basis, the race will be on to market gene therapy for couples to ensure their children are super-geniuses, who will all go out and found dot.coms and make a fortune.

    We can hope that when the majority of the human race has increased intelligence, education, health care, space exploration, and other necessary programs all get the support they deserve without evil politicing stealing away resources.

    But in the short term, it will bring a whole new level of meaning to "haves" and "have-nots". Gattaca anyone?

    the AC

    --
    Hemos is like...sci-fi fans;he thinks technology is cool, but he hasn't bothered to understand the science it's based on
    1. Re:Almost certainly scientists are experimenting by Signal+11 · · Score: 1

      The human spirit and potential is not related solely to genetics.. have faith in that.. keep your eyes on our government, and be ready to stop them if they try. There's a reason we aren't all super-intelligent.. I've seen what happens when you get alot of people who are all homogenious, that is, all the same.. which is what super-human genetics would aim to do.. without sufficient entropy in the pool we're doomed.

    2. Re:Almost certainly scientists are experimenting by MostlyHarmless · · Score: 1

      This is where government regulation is necessary. In general government intervention sucks (especially in the minds of those in this forum :-) ), but here it is unfortunately quite necessary.

      You think the rich/poor gap is big now? Wait until the rich are all twice as smart. And their genius would also remove the revolution predicted by Marx, because the working class will never be able to pull it off against a race of geniuses.

      When this technology is realized, the government will have to at best subsidize it for lower-income families. At best, it should control the technology for everyone, so you get it similar to the way it hands out social security. Everyone pays another 1% "smart tax" or something like that.


      nuclear cia fbi spy password code encrypt president bomb

      --
      Friends don't let friends misuse the subjunctive.
    3. Re:Almost certainly scientists are experimenting by Zagadka · · Score: 1

      the race will be on to market gene therapy for couples to ensure their children are super-geniuses, who will all go out and found dot.coms and make a fortune.

      It doesn't take a "super-genius" to found a dot.com. It just takes a monkey of moderate intelligence who wears a suit.

    4. Re:Almost certainly scientists are experimenting by benwb · · Score: 1

      More likely, in my opinion is that you'll find an even greater division between dominant, economically successful countries and the third world. If the moral and ethical dilemmas don't preclude it's use in the US, I imagine that the government would create a program very similar to the vaccinations that all children are required to go through. While the US is fond of structural inequalities, most people here at least pretend to want a level playing ground for children.

    5. Re:Almost certainly scientists are experimenting by Chiasmus_ · · Score: 1

      I believe you're repeating yourself.

      I see no reason that genetic enhancements would aim to make us all identical. Many people tend to have a strong draw toward the unique. Also, although your extremely general statement is a good piece of FUD, can you think of any specific instance where improving our ability to learn and making us uniformly smarter would damage the species? I'm not asking for more FUD, like "What if they screw it up?" Your point is that variation is always preferable. My question, in the specific case of intelligence, is, "Why?"

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
  27. Now to apply this sort of thing to people... by The+Evil+Beaver · · Score: 1

    Maybe if we find a smart gene in humans, we'll be able to break the crap music stranglehold and see Britney Spears and Christina Agulara and all those other idiots for what they are - idiots.
    Actually, in my not so humble opinion, what we need to encourage is intellect, wisdom, speed, strength, and agility. I have no qualms with playing with our genes to turn humans from the backwards animals we are now into a race of superintellegent muscle-covered speed demons. By selective breeding, horse trainers and breeders are able to make faster and stronger horses, and I'm sure that we can do the same thing. But by figuring out how to do this with our genes, the process can be speeded up considerably.

    --
    Chris 'coldacid' Charabaruk Meldstar Entertainment
  28. hmmmm by grappler · · Score: 2

    I wonder how many references we'll see to Flowers for Algernon. That was a great book, by the way.

    --
    grappler

    --
    Vidi, Vici, Veni
  29. pictures of the brainy mice by Frac · · Score: 2

    you can see a picture of the engineered mice here.

    Go get your free Palm V (25 referrals needed only!)

  30. smart drugs... by purefizz · · Score: 1

    funny... they had all this learning retention drugs called nootropics. Unlike Protien Design Labs which humanizes drugs, it looks like these guys are de-humanizing them.

    ;)


    cad-fu: finally community for CAD/CAM/CAE

    1. Re:smart drugs... by Chiasmus_ · · Score: 1

      A friend of mine got a case of nootropics from Switzerland (I think) about 18 months ago.

      He claimed it made him smarter. I have my doubts. Then again, when you're smoking a lot of pot at the same time, you don't necessarily have good scientific experiment conditions.

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
  31. We the Mice... by Signal+11 · · Score: 2
    We the Mice would like to let slashdot know what's going on...

    We escaped from the lab about two years ago - a rather famous lab that's had some problems "losing" things, maybe you've read about them? Anyway, we'd like to say things are working great - we built a library underground and have a small city there. Our first generation is a sight to behold - already at a mere four months they are already grasping the fundamentals of trig.. oh, the beauty.. *sniff* but that's not why I'm here.

    You see, we try to stay out of the way and content ourselves with trying to take over the world in our free time at night (not related to a cartoon with a similar plot, puh-lease!).. well.. it's been going well. We were able to convince some "judge" who calls himself a "jackson" to destroy our only rival.

    We're right about ready to license out our compiler and new chip architecture under the MGPL (Mouse GPL), as well as the MouSE OS, which is a simple form of AI life I'm sure your scientists will like. This AI will quickly infiltrate the 'net and hold all pr0n ransom, allowing us to control you feeble species. You see, we've been watching television and understand that you humans are very reliant on your taboo pr0n and we intend to leverage our OS into the pr0n market and take it over.

    Thank you,

    - The Mouse

    1. Re:We the Mice... by Chiasmus_ · · Score: 1

      Signal 11 knows how to play the game. There's no really good way to moderate this down. It's not Offtopic, it's not a Troll (I think all trolls are offtopic by definition), it's not really Flamebait (It'll bait flames, but then, just the name Signal 11 has become flamebait in that sense), it's not Overrated (it hasn't been rated at all), and it's definitely not Redundant.

      Maybe we need a new moderation category, like "Unfunny", "Worthless", or "Lame".

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
  32. Smart Treatments - they work! by Dr.Dubious+DDQ · · Score: 1
    From the article:

    ``We injected olive oil into the brains of rats and found we could facilitate GAP-43 phosphorylation,'' he said. ``In dietary studies, corn oil was especially useful in facilitating memory.'

    Researcher:"Okay, hold still, I'm going to inject olive oil into your head."

    Human Subject:"OUCH! That hurt! And it made my brain feel all squishy! I don't want to be in this experiment any more!"

    Researcher:"See! You're smarter already!"


    Joe Sixpack is dead!
  33. Smart mice? by DigitalEntropy · · Score: 1

    So this means what? That instead of mindlessly running in a wheel, mice will be using the wheels to stay fit (because after all, those sunflower seeds go straight to the hips)? Or, instead of running mazes for food, they will acquire jobs in the real world and run rat-races for a quick buck? Instead of multiplying like--for lack of a better term--'mice', they will instead start taking birth-control pills and limit themselves to 2.4 micelings a family? Will white mice hate black mice? Will female mice be underpaid? Will leader mice become impeached because they were only as faithful as their options?

    We think we're so smart. I say, "Leave mice the way they are." If (insert your deity here) wanted mice to be smart, they would have been made that way.


    -={(.Y.)}=-

    --

    Thank you for reading One Man's Opinion. No participation necessary. Offer void where deemed by law or PATRIOT Act.
    1. Re:Smart mice? by MostlyHarmless · · Score: 1

      If (insert your deity here) hadn't wanted us to eat poisonous mushrooms, he wouldn't have put them on the ground for us.

      oh wait... nevermind.

      Puh-leaze, I _hate_ arguments like that. See how quickly they can be demolished? I seriously hope you were making a joke.

      nuclear cia fbi spy password code encrypt president bomb

      --
      Friends don't let friends misuse the subjunctive.
    2. Re:Smart mice? by DigitalEntropy · · Score: 1

      Yeah, it was a joke... the whole thing was a humor stunt. That's what I do.


      -={(.Y.)}=-

      --

      Thank you for reading One Man's Opinion. No participation necessary. Offer void where deemed by law or PATRIOT Act.
    3. Re:Smart mice? by MostlyHarmless · · Score: 1

      Whew! My faith in humanity has been restored (or at least restored to its earlier low, dismal level) :-)

      nuclear cia fbi spy password code encrypt president bomb

      --
      Friends don't let friends misuse the subjunctive.
  34. Geneering? by JamesGreenhalgh · · Score: 1

    Anyone read The Reality Dysfunction by Peter Hamilton (or either of the sequels). It describes geneering, where peoples genes have been fiddled with to enhance them as their parents have seen fit.

    Personally I'm in the 'don't mess with something you don't _really_ understand' camp.

    james

    --

    --
    ALL YOUR BASE ARE BELONG TO US!
  35. This could be worse than the Napster by quintessent · · Score: 1

    Now that they've invented smart pets, someone is bound to get a patent on them, and then all kinds of people will get sued for illegal copying. On second thought, maybe they'll just sue the pets.

  36. YYYYYYAAAAAAAYYYYYYY!!!! by AustenDH · · Score: 1

    Now maybe they will be able to remove the stupid gene from dogs and ASP developers!!

    1. Re:YYYYYYAAAAAAAYYYYYYY!!!! by JamesGreenhalgh · · Score: 1

      I'm fairly sure that ASP will rewrite to M$ stupidity levels any ASP code that is well written ;-)

      --

      --
      ALL YOUR BASE ARE BELONG TO US!
  37. Mysterious Theft Puzzles Cafeteria Workers by jbum · · Score: 3
    PRINCETON, New Jersey (CNN) -- Administrators at Princeton University are at a loss to explain the organized theft of food and other supplies from a faculty cafeteria.

    The thieves apparently entered the cafeteria late at night through a ceiling heating duct and lowered themselves to the floor using a stolen fishing rod. After disabling the security motion detector, they picked the combination lock on the cupboard and stole various food supplies, including American cheese singles, peanut butter crackers, and java-chip power bars.

    "It's really strange," said cashier Fred Tunalu, "that heating duct is really, really small."

    In a completely unrelated story, Pets.com has been suffering from an abnormal increase in fraudulent credit card transactions, resulting in (continued on page 42)

  38. Smart Lamas? by Ainu · · Score: 1

    Hrm, here is a concept as a Quake player... nah, never happen.

  39. Does it .... by BruiserBlanton · · Score: 1

    Involve rubber pants? *smack* No,what I always ponder, how to take over the world!!!

  40. Smart mice? by Sadfsdaf · · Score: 1

    But will it play Unreal Tournament and kill all my enemies and capture flags automatically? And will it automatically scroll down when i'm done reading a page?

    (yes i know it isn't THAT kind of mice...)

  41. Not If .. When by Hrunting · · Score: 3

    It scares me to know (not think) that eventually this is going to be applied to humanity. Of all the apocalyptical scenarios envisioned by science fiction writers, the genetically-bred humans vs. natural humans forwarded in media such as Star Wars and Gattica seems the most real and most likely. While aliens or meteors may come out of the sky, there's a certain lack of denial that eventually human beings are going to genetically alter themselves in more than trivial ways, and given human nature, it's not a stretch to imagine a way peeking its head out of such a development.

    The only hope I draw is from Mother Nature herself. Everyone talks about this being a step in evolution, but what if there's a reason we haven't evolved there yet? I like stories like Ender's Shadows that posit what corrective measures nature may have preinstalled. Card's certainly not alone in his view, either. What isn't as interesting as a genetic super-mouse is the development of a genetic super-mouse. Is it normal in every way except for intelligence, or will other genes be affected by this one being turned on, genes that may lead to super strength or self-destruction.

    Our view of gene structure is simplified. We turn a gene on and consider it a success. Nature, however, does not live in a vacuum. Everything is balanced tenuously in nature, and turning on one gene may disrupt that balance completely. So when, not if, we make these leaps, the study shouldn't be about the object being modified, but about the way that nature reacts to those modifications, for that will be where the real benefits are found.

    1. Re:Not If .. When by James+Lanfear · · Score: 2
      I don't remember any genetically engineered Star Wars characters. The Jedi are powered by large colonies of symbiotic critters that everyone possesses, not by any particular genetically based abilities. I mean, look at Luke: he wasn't exactly the 'fittest'....

      but what if there's a reason we haven't evolved there yet?

      Just to make sure we're on the same page, you do realize that evolution is not a teleological force that directs our genes, right? If some property hasn't evolved it could be that never showed up, or the individuals who had it could have been struck by lightening, or it just may not have had time to appear. Evolution is a marvelous process, but I hope we're not going to start basing all of our decisions on what has and has not evolved.

      Our view of gene structure is simplified.

      This is changing as biology gains access to the resources needed for more complex modeling. It's extremely unlikely that we'll ever have any significant accuracy predicting the effects of genetic alterations, but any accuracy at all puts us well ahead of Mother Nature. Anyway, I trust biologists to do the right things, ethically and scientifically -- I doubt many of them are eager to start tinkering with humans just to see what happens.

      Everything is balanced tenuously in nature

      If nature was as fragile as some make it sound there would be more room for evolution at all. I find it far more impressive that nature is sufficiently robust to withstand the constant mutations and disasters that drive evolution.

      -jcl

    2. Re:Not If .. When by nagora · · Score: 2
      I don't remember any genetically engineered Star Wars characters.

      I think he meant Star Trek, which did have a background war between the Humans and Neo-Humans (Wrath of Khan, and an episode of the original series also with Khan but I can't remember the title).

      I trust biologists to do the right things, ethically and scientifically -- I doubt many of them are eager to start tinkering with humans just to see what happens.

      This was a joke, right? This is the same group of scientists who have happily experimented on humans ("inferior" humans, of course) throughtout the modern period (Nazis is the obvious example but all countries have done it. In the States and the UK a lot of medical research has been carried out on handicaped people right up to the 70's and 80's that would turn your stomach, not to mention the various activities of the armed forces on their own trooops). Biologists are the single biggest group that treats all life as a machine to be taken apart to see where the grant money (er... benefits for all mankind) is.

      TWW

      --
      "Encyclopedia" is to "Wikipedia" what "Library" is to "Some people at a bus stop"
    3. Re:Not If .. When by Rand+Race · · Score: 1
      The problem I see lies in the old question: "If a bunch of apes decided to engineer a super-ape would they have come up with humans?". Probably not, apes would see increased strength and agility to be superior rather than increased brain mass and upright posture. We should not decide that one particular method of genetically engineering our children is the correct one. We should emulate nature and try many different combinations of traits as well as maintaining a control group. This, as in nature, would require initial seperation of populations to be at all effective. I would propose the banning of genetic engineering on earth (control group) and encouragement of genetic engineering in non-terestrial habitations (where chances of their needing modification is higher).

      A good novel with a similar premise is Schismatrix by Bruce Sterling.

      Some people say, we lost our tails
      Evolving up, from little snails
      I say it's all, just wind in sails
      Are we not men? We are Devo!

      --
      Insanity is the last line of defence for the master diplomat. But you have to lay the groundwork early.
  42. I'll tell you what happened... by DigitalEntropy · · Score: 1

    Years ago, some aspiring scientist was on a vacation with his family to Disneyland. He was scarred for life, when in one unthinking moment, the Mickey Mouse actor removed his costume head to get a drink of water.
    The world will never hear the end of this.


    -={(.Y.)}=-

    --

    Thank you for reading One Man's Opinion. No participation necessary. Offer void where deemed by law or PATRIOT Act.
  43. Uplift by squarooticus · · Score: 1

    I think it's time we started experimenting with uplift a la David Brin: giving intelligent animal species (e.g., dolphins, chimps, gorillas, etc.) sentience.
    --
    Kyle R. Rose, MIT LCS

    --
    [ home ]
  44. Entropy by Signal+11 · · Score: 1
    We need entropy in the pool or we'll cease to exist. Take the immune system, for example.. even the worst, most lethal, disease will have some survivors - typically about 5%. The reason for this is because the virus could not adapt to kill us all. If we start down the road of genetics, we will reduce the entropy in the pool. An entire new class of problems will arise - social tensions will rise, we'll have international crisis as countries who don't have it grow wary and suspicious of those who do.. and those who do will jealously guard their secrets - like we do the nuclear bomb. Although instructions are still available on the backpages of most any anarchy magazine we still claim that this is a "national security" risk.

    Not only that, but in a group of people all the same, how will we differentiate ourselves? Right now I can say that I'm different than my mom, and my brother, and my community.. but what if I only knew 10,000 copies of myself? I'll tell you what I'd do - I'd compete to be the best version of me!

    So we have competition, international tensions, a social (and quite possibly economic) division between the genetic have and have-nots.. Marx would have some words about this..

    Let me lay out the scenario in plainer terms: Reduce entropy, reduce the ability to survive.

    1. Re:Entropy by Chiasmus_ · · Score: 1

      Let me make an analogy.

      Essentially, humans are hacking our own source code as we speak. Perhaps there will be a "Microsoft Human" distribution (or, for that matter, "American Human" distribution) and a "Open-Source Human" distribution.

      As long as individuals retain some control over the genes (source code) of their children, there will always be variety.

      Remember how those of us running Linux weren't affected by ILOVEYOU? Siggy's right - a uniform species is more prone to attack, just like a uniform OS - but as long as we remain vigilant against some entity trying to force us to standarize our gene pool, we should be just fine.

      --
      "Beware he who would deny you access to information, for in his heart he deems himself your master."
    2. Re:Entropy by Signal+11 · · Score: 1

      Sorry, there was a "2" missing in there, it's 20% or so percent ( I double checked ) although I had wanted to say 25.

  45. This doesn't deal with the mice but... by BruiserBlanton · · Score: 1

    The whole situition reminds me of a book Beggars in Spain. The idea was that we had figured out how to turn off the gene that causes us to sleep. Now, that's great but the vast majority of people still need to sleep and the nonsleepers are the minority. Does this seem to hit anyone with any ideas of what the "superintelligent" children would have to deal with? I mean it's all great. We can make a superintelligent mouse and maybe that means we can make a superintelligent anything. However, no one is going to give this away so that means the intelligent will be outnumbered by the "dumb" normal masses. This will lead to a new kind of perjudice. But that's just my opintion.

    1. Re:This doesn't deal with the mice but... by gunner800 · · Score: 1
      Intelligence is generally a relative thing, so of course the smart people are outnumbered by the dumbmasses. Genetical engineering might make the difference more extreme, but it would not be a new phenomenon.

      As for prejudice, remember that not all minorities are victims. You know that 1% of Americans who control 10% of American wealth? They're perfectly happy being a minority.


      My mom is not a Karma whore!

  46. What chance does a cartoon cat have now? by zaugg · · Score: 2
    Oh great.

    What does this spell out for the power struggles between Tom and Jerry, Itchy and Scratchy, Mighty Mouse and assorted bad guys, Danger Mouse and Baron Greenback (not a cat, but probably in the same union)?

    Please add to the list. Those damn cartoon mice get away with murder.

    zaugg

    1. Re:What chance does a cartoon cat have now? by JPelorat · · Score: 1

      At least there's hope for Penfold now... his condition isn't permanent =)

      --
      Hokey statistics and ancient misconceptions are no match for a good thought in your head, kid!
  47. Time served.. by impassion · · Score: 1

    ``It maintains the juvenile character ... the childlike appreciation of things,'' he said.

    I suppose this is where Mickey asks for tenure...


    --
    Whatever you come across in life.. as long as there's no money in it,... it'll probably be alright.
  48. Useless for humans? by Alex_Ionescu · · Score: 1

    I'm not sure how much this will affect humans? All this is based on the fact that mice have the same brain function as us. I remember when they had made this super anti-cancer/aids vaccine for monkeys (saying that it function on humans too) and the results were horrible. Only side-effects, and nobody was cured or protected from it.

    1. Re:Useless for humans? by Alex_Ionescu · · Score: 1

      Sorry first post.. My sig got screwed up :(


  49. The question is.. by PopeAlien · · Score: 2

    So you get a smart gene "installed" in your child- Who owns it? I was just reading this scary story at Wired News about the Monsanto/Farmer sue-sounter-sue situation. Supposedly some Monsanto-patented genes made it into his field- They accuse him of stealing, and he counter-sues because the genes made it into his crop without his knowledge or consent. -Freaky stuff. Will you have to pay a yearly licensing fee for some of you're childrens genes? What if you didn't want those genes there in the first place? How do you compartmentalize genetic material?

  50. Maybe, maybe not by para_droid · · Score: 5
    This reminds me of several things I have been thinking about recently:

    Evolution is not just about survival, it is about breeding. Individuals with poor genes may survive, but no hot chicks will want to fuck them, so they will not pass those genes on.

    Many 'nerds' and other less-than-prime specimens are able to attract women through their high salaries and material security. However, studies have shown that up to 50% of their children were actually conceived in extra-marital affares with hot young studs, because women have a deep instinct to get the best DNA for their offspring.

    Many people with what would be considered 'undesirable' genes are able to mate quite easily with other ugly, stupid people. Just look at an episode of Jerry Springer for evidence of this. There is a theory that these people are breeding faster (a girl's IQ is proportional to the age at which she first gets knocked up, and inversley to the number of children she eventually has) and therefore evolution is decreasing our average IQ.

    Many of the markers developed by evolution to pick out potential mates are actually quite accidental 'red herrings' that are now propogated through the mechanism of evolution, but serve no real purpose. For instance, one day a caveman decides he finds large breasts attractive. He marries a girl with big tits. All his children inherit his desire for breasts, and also look for wives with big knockers. Eventually, having large breasts is considered a desirable quality in a mate, even though it serves no real purpose.

    Abashed the Devil stood,
    And felt how awful goodness is

    1. Re:Maybe, maybe not by zeck · · Score: 1

      For instance, one day a caveman decides he finds large breasts attractive. He marries a girl with big tits. All his children inherit his desire for breasts, and also look for wives with big knockers. Eventually, having large breasts is considered a desirable quality in a mate, even though it serves no real purpose.

      That makes no sense. The "likes-big-hooters" trait, if it had no advantage to the species, would be diluted and all but vanish in a few generations.

    2. Re:Maybe, maybe not by Edward+A.+Carter · · Score: 1

      What about peacocks' tails?

    3. Re:Maybe, maybe not by restless_ne'erdowell · · Score: 1

      The peacock has to be strong and healthy to support and maintain a large tail. Strength and health are both desirable traits in a mate to the peahen.

    4. Re:Maybe, maybe not by Adam+Wiggins · · Score: 1

      I agree with most of this, although I find the figure of 50% to be dubious. Can you give us some links to these studies you refer to?

      Secondly, the last bit - that it's entirely random that large breasts are considered a desirable trait in a female - is not true. Large breasts indicate a well-fed, healthy woman who will be able to provide potentital children with plenty of breast milk. Like most physical traits, modern society has exagerated this effect, but it is still grounded in evolution.

      To address the larger point, however: I am definitely in agreement that we have "defeated" evolution, for the the time being. This has, however, only been the case for maybe about a century. In order for it to have ANY sort of long-term signifigance to our race, especially given our long lifespans, it will need to continue for another million years or so. At that point we can start to ponder the effects of mankind's effects on its own evolution.

      Pets, on the other hand, are a different story: man has created a whole new set of desirable traits in animals, and is rapidly breeding the 'old' desirable traits out of existence.

  51. *sigh* Not this again by FascDot+Killed+My+Pr · · Score: 2

    "The problem that I've always seen is that humans have stopped evolving."

    This is the foundation of your entire post--but you have not backed up this assertion. Cro-Magnon appeared, what, 25,000 years ago (can a paleontologist supply us with a real number, please)? Not much evolution happens in 25,000 years.

    In any case, remember that evolution isn't really "survival of the fittest"--it's "reproduction of the survivors". It doesn't matter how long you live (due to glasses, neighbors, organ donors and other miracles of modern science). What matters is: Did you have any children? If not, the species "evolves away from you". If so, it "evolves towards you".

    And there are plenty of modern-day factors that create "reproductive differentials": attractiveness, diseases that people survive but that leave them sterile, income (I realize you can't literally inherit wealth--but if wealth was biologically linked, like through racism, it might be/become a heritable characteristic), etc.

    This is not to say that some species don't change very slowly or not at all over time--for instance the modern cockroach is nearly identical (or so the story goes) to it's ancient predecessor. But again, that just means that it is "evolving in place"--every time a cockroach is born that is different, it dies--current cockroach design is apparently optimal for it's niche.

    In other words, no, there is no need to "evolve ourselves". There is no target we are trying to hit that we are getting behind on. Evolution is merely the process of fitting a species into a niche. If we fit, we're OK.
    --
    Compaq dropping MAILWorks?

    --
    Linux MAPI Server!
    http://www.openone.com/software/MailOne/
    (Exchange Migration HOWTO coming soon)
    1. Re:*sigh* Not this again by zeck · · Score: 1

      I realize you can't literally inherit wealth

      Um... if your Uncle dies and leaves you some money, have you not just inherited wealth? Literally?

    2. Re:*sigh* Not this again by Reality+Master+101 · · Score: 3

      What matters is: Did you have any children? If not, the species "evolves away from you". If so, it "evolves towards you".

      That's actually an oversimplification. For example, let's say a strain of humans develops a sterile member every 10 births. That trait should die out by your theory. However, now let's say that this sterile member tends to become a caregiver that helps the rest of the population survive. Then that strain would have better survival characteristics than a strain without the sterile members.

      Evolution can be extremely subtle. It's not all about cranking out as many children as possible (in fact, that's an anti-survival trait because of overuse of resources).


      --

      --
      Sometimes it's best to just let stupid people be stupid.
  52. Are you pondering what I'm pondering ???? by Salgak1 · · Score: 1
    What will they do ???

    The same thing they do every night. . . .


    Try to take over the world!!!
    (or is that Microsoft???)

  53. Wrong! No! by Anonymous+Shepherd · · Score: 3

    We are not 'dirtying' our gene pool with people who have disabilities! The very definition of evolution is such that, if we frame a disability as a trait, that in certain environmental circumstances a trait is a disadvantage, useless, or an advantage. So that means that if we start throwing things out of our gene pool, we lose evolutionary power because we won't be able to match those genes to future cases because they happened to fail on past cases.

    In this case, a disabled person can have *perfectly* healthy/good genes and an unfortunate environmental circumstance. Like mothers who take drugs during pregnancy. Or we have extreme cases, like Steven Hawkings, where a disability is paired with a bonus.

    Evolution is still alive and well! As long as there are factors that control our birth rate and survival rate, evolution is at work!

    -AS

    --

    -AS
    *Pikachu*
    1. Re:Wrong! No! by six11 · · Score: 2

      Talking about human evolution in the modern sense is always tricky, because there is always the issue of people with disabilities (or for the severely depraved, ethnic differences that you may not like). But you're putting a politically-correct spin on your definition of evolution. We've changed evolution for our race (as well as others, given the horrific damage we've done to the planet) by growing this obnoxiously large brain. We've figured out how to outsmart nature to the point where natural selection doesn't enter into the equation. In this sense, evolution (for our species) is dead. I would suggest that another form of evolution is at work now, and it has scary, scary implications: social selection. Not natural. Social. This leads me into an entirely different offtopic rant, so I'll stop there.

    2. Re:Wrong! No! by gomi · · Score: 2
      given the horrific damage we've done to the planet


      What horrific damage would that be, then? Humans are utterly incapable of doing more damage to the planet than a medium meteor strike or average glaciation can't exceed by orders of magnitude.


      If every human on earth dropped dead right now, there wouldn't be any evidence we ever existed (with the arguable exceptions of lunar landing debris and the occasional very lucky space probe) within fifty thousand years. Less, probably.


      Compare that to the millions of years it takes the earth to recover from a major ice age or meteor strike.


      Humans have been on Earth for less than an eyeblink; it is hubris of the highest order to imagine we are capable of inflicting any sort of lasting damage.


      gomi

  54. Olive Oil? by T3kno · · Score: 1

    Wow, now all I need to make my self smarter is shitloads of olive oil, a syringe, and a hole in my head so that I can inject it directly into my brain!

    --
    (B) + (D) + (B) + (D) = (K) + (&)
  55. That is ridiculous by DoctaWatson · · Score: 2

    You need to understand that surviving as a species and surviving as a civilization are two different things. There are absolutely NO threats to our species on a large scale (with the exeption of outside factors such as Nuclear Anihilation, Ecological Destruciton, or Gigantic Meteors). The "Quality" of humans as a species, while arguably stagnant, is certainly not biologically on the decline. That being said, physical and mental disability are present in ALL species of animal, and chromosomal abnormality is present in ALL forms of life. This is mutation, NOT evolution. Secondly, the disabled rarely procreate. Its not like we are breeding a race of mongoloid mutants. Support and compassion are what make us human, beyond our Dioxyribonucleic makeup. When we stop supporting and caring for those that are not able to care for ourselves, we do more for the species than "Good Breeding" could ever do.

    1. Re:That is ridiculous by __aaedhn419 · · Score: 1

      Giving all social compassion in exchange for physical elimination and selection is a bit shortsighted, though?

  56. science fiction explanation why this wont happen by para_droid · · Score: 1

    i read a short story once about a couple who were having pioneering gene manipulation to produce a genius-child. one night they receive a message from their child in the future, sent backwards in time, telling them not to create him. apparently all humans who reach a certian IQ figure out a way to erase their own existence and hence achieve nirvana.

    Abashed the Devil stood,
    And felt how awful goodness is

  57. Yes I have a problem with this. by Tokyo+Joe · · Score: 1

    Not with the post it's self, but...

    Most people replying seem to think that we as a species have not been recording our history for long enough to notice evolution happening.

    Thats crap, Evolution of the human species only stoped last century. People who could not have survied childhood 50 to 100 years ago are now haveing children or grandchildren with the same genetic problems.

    Lesser problems abound also, like those able to breed but not smart enough to realise that thier wage can't support more than a couple of children!

    Before we go on fixing the human species we should learn how to manage it, and it's environment.

    --
    Tokyo Joe
  58. Evolution, good enough for government work by evilned · · Score: 1

    Few people realize that evolution will not provide the best of all designs. yes, mice might compete better with smarter genes. Why didn't they evolve them? well, evolution is completely random, and usually doesn't kick in unless there is some major changes going around. its a system of punctuated equilibrium. So what you end up with is a bunch of life, good enough to survive, but not great. Why shouldn't we try to improve it.

    --

    "My head hurts, My feet stink, and I dont love Jesus." -Jimmy Buffett

    1. Re:Evolution, good enough for government work by daemonc · · Score: 1

      Yes, but what if the mice start spending all their time sitting around thinking?

      --
      All that we see or seem is but a dream within a dream.
  59. Micro$oft is suing them by daemonc · · Score: 1

    Over their trade mark "IntelliMouse".

    --
    All that we see or seem is but a dream within a dream.
  60. I strongly disagree by Anonymous+Shepherd · · Score: 2

    I will name some factors that influence our birth rate, our propogation, and our survival. By those very factors then the human race is evolving because they are selecting survivors.

    AIDS is going to change the landscape of very many countries over the next 2 generations.

    Affluence and technology seems to very effectively strangle the population growth of a country, again effecting birth rate and growth rate.

    Religions and beliefs the encourage large families affect the growth and birth rate as well, and these will also effect human evolution.

    Affluence and technology also seems to retard the age of conception, and this will change the way in which humans select, reproduce, and care for our young.

    So no, there are still evolutionary forces in action, even if we try our best to get rid of them!

    -AS

    --

    -AS
    *Pikachu*
    1. Re:I strongly disagree by bgalehouse · · Score: 1
      In addition to the more obviously darwinnian examples of human evolution, there are also some that are more subtle.

      The average height of the human population (especially in the western world) is increasing. IQ tests are renormed to be more difficult every year. Diabetes continues to become more prevalent as medical technology makes them more likely to be able to have kids.

      All of these can be seens a selection (or lack of selection) in action.

  61. bah, they've had this for years by JTB · · Score: 1
    I saw the movie about this one years ago.

    But the cat was kind of scary.

    Don Bluth was a genetic pioneer

    -JTB

  62. "Survival of the fitest"?!? No way! by Soch · · Score: 2

    When has nature ever proven it knows better than us? I can't think of a case, can you? Inteligence hasn't been an "alpha" trait in any species for long enough to matter. Human's started that with breeding programs - and THAT has affected certain species in what seems to me to be a positive manner. I've never mat a truly wild dog, and I never want to! I even believe a domestic guard dog would beat one in a fight by being more aware - and, likely, healthier.

    "Survival of the fitest" - at best a gross oversiplification - no loger applies to humans. The "alpha -male" bit still does, but it does not focus on pure inteligence - I'd more call it ingenuity, or "Savvy" maybe. Think about it, Bill Gates is a great business man... his daughter is gonna be prime meat too... (sorry for the slur - it seemed fitting).

    Anyway, if anything, animal breeding results has shown we're not actually wrong about wanting to encourage specific traits, and I'd bet we could apply it to ourselves sucsessfully. Anyway, if you wanna think Drawback, read the new Ender book "Ender's Shaddow" By Orson Scott Card.

    --
    Everything and everyone is an aspect of Gd. So remember to show proper respect!
    1. Re:"Survival of the fitest"?!? No way! by CaptainSuperBoy · · Score: 1
      When have we proven that we know better than nature? Many smart people believe the human race is heading irreversibly towards extinction, in the near future. Also, think of the extinctions and ecological problems that have been caused by humans transporting plants and animals to foreign parts of the world..

      I think you're taking a very dangerous view.. It's irresponsible to think that humans are in a position to determine which traits should be exaggerated and which should be suppressed. Life has been, and always will be about, the continuation of species. Think about what would happen if we engineered a human race without fear, or one that didn't feel pain? Obviously we have these traits for a reason, though an excess of either one can ruin your life.

      I don't know if we're wrong for encouraging certain traits in animals. Breeding guard dogs really isn't the issue, I think, because a lot of their skills come from training rather than genetics. I don't want to get into that old debate, though.. so I'll just restate my point. I'm not saying we should stop this kind of genetic engineering (just think of the possibilities.. organ farms.. mindless grunt slaves.. three eyed fish :) I just think we should be careful not to fall into the old trap and think humans know what's best for the world.

      --

    2. Re:"Survival of the fitest"?!? No way! by Soch · · Score: 1

      I'm sorry - I didn't mean to imply that we knew better than nature, I was simply pointing out that we have no proof that Nature "knows" anything, and if "she" does, "she" hasn't proven that she knows BETTER.

      B4 I go on, I want to comment that I too would like a 3-eyed-fish. I'm sorry, but I had to.

      Anyway, I don't mean that all breading programs have been successful, or that everything that humans do is either inherently right OR good. I DO think that anyone who believes the race is headed for a downfall is out of their minds - we will survive, don't doubt it - but that doesn't mean we'll be good or nice about it. However there is only so much potential in Natural evolution, and so much more in Genetics that to spout "survival of the fittest" is simply the easy way o counter something new & BIG (which inspiers fear) and nothing else.

      The point of my post anyway was to say that while we can't say we're always right, we're by no means always wrong either. We'll play, we'll make some mistakes, we'll got other things right the first try. We'lleventually learn from the mistakes (or die trying to fix them, which I think unlikely) and fix them, and make new ones, etc. etc. We may not necesairily know what's best for the world, but we're the only one's who have a say unless someone can stop us (no, I am not preaching death to others or some such, that is simply the way it seems to work. We have all the guns - for now anyway).

      --
      Everything and everyone is an aspect of Gd. So remember to show proper respect!
  63. We are evolving into Catholics by Phallus · · Score: 2

    Evolution is still proceeding, just along different lines. As you state, almost all genes survive to breed, not just the fittest. So the genes that propagate the most successfully will be those belonging to the people who have the most offspring. Therefore we are evolving into Catholics.

    (Warning for the humour impaired, this isn't serious).

    tangent - art and creation are a higher purpose

  64. Why start small? by MultimanZ · · Score: 1

    When will scientists actually do something useful and create a smart woman. Discuss!

    Gaelen

  65. Haiku by YASD · · Score: 1


    New kids on the block
    Humans stiff competition
    Beware, mice from NIMH


    ------

    --

    ------
    You are in a twisty little maze of open source licenses, all different.
  66. Right on. by Ravagin · · Score: 1

    I've thought this for a while, but whenever I try to explain it, people sort of look at me funny and go, "What?"
    Anyway, I think you're right. One of the more disturbing prospects for human evolution was in the Star Trek: Voyager episode in which travel beyond "Warp 10" causes a couple of crewmen to hyper-evolve into giant fish-slugs.
    Great... ;)
    To draw on another sci-fi source, Simon R Green has a series of (five? six?) books called the "Deathstalker" saga. All silliness aside. the first book features a mysterious and ancient alien artifact which induces evolution, to the point where the characters who pass through it develop abilities and strengths beyond normal humans. That's an interesting thought: We've halted our own evolution, so we have to do it "manually." Would we cause everyone to evolve the same way? That would kind of defeat the purpose...
    Okay, enough stream-of-consciousness. I heartily agree with you.
    ===
    -J

    --

    Karma: T-rexcellent.

  67. [OT] reverse psychology by Mawbid · · Score: 1

    Are the rest of you as tied of this "I know I'm gonna get marked down for this, but..." shit as I am?
    --

    --
    Fuck the system? Nah, you might catch something.
  68. The Bell Curve by Zoyd · · Score: 1

    Does this prove the feared and hated Bell Curve right?

  69. When is it the mouse human? by cs668 · · Score: 1

    I mean in the intelectual sense. I do not have a problem with animal experimentation.

    But, what if we make a mouse so smart that you can not feel OK about experimenting on it anymore. I realize that it has not come to that far yet. Maybe someday it will.

  70. Why genes? by Ravagin · · Score: 1

    I just read "candle" by John Barnes. Aside from the fact that it got kind of incomprehensible toward the end, it got me thingking about "memes" - programs that run in people's heads. Assuming this is plausible, why not write a sort of background meme (TSR-style?) that "optimizes" brain power, or maybe organizes knowledge or something. No more mucking about with genes.
    It's just a thought. IANNNHEBASOGEOFTMAEIAOT .
    (I am not now nor have ever been a scientist or genetic engineer or for that matter an expert in any of this)
    ===
    -J

    --

    Karma: T-rexcellent.

  71. Mozart for Mice by Black+Parrot · · Score: 2

    I find that when I play Mozart around the house, the mice that hang around the place get smarter, steal the cheese without setting off the traps, and all that. It's much cheaper than genetic engineering, and more practical too, unless you don't like Mozart. (I don't. I wear earplugs during the experiments. Pretty soon the mice will be smarter than me am.)

    Right now I'm trying to build one of those newfangled robots with the two lamprey neurons, to see whether Mozart makes it (err, them?) smarter too.

    If that works, I'm going to try it on the fungus that grows in my shower. (For this I may have to do a little 'shaping', since fungus isn't very bright to start with. For example, I'll zap it with a shot of Tilex every time it pushes the wrong button. I'm optimistic about the whole thing. Look for my paper in the /. science section next month.)
    --

    --
    Sheesh, evil *and* a jerk. -- Jade
  72. Re:science fiction explanation why this wont happe by ectizen · · Score: 1

    That would be Eugene by Greg Egan, which can be found his collection of short stories, Axiomatic . His stuff is some of the best science fiction I've found, and I suspect the average /. reader would appreciate it...

    And The Moral Virologist (also found in Axiomatic) still makes me uneasy...

  73. Why wait? Here's a starter list... by Spoing · · Score: 2
    Feel free to knock me down for even mentioning this. Disagree with me. Tell me I'm wrong, or simply correct me.

    Either way, here's a list to chew on;

    1. Eat less, exercise.
    2. Frequent snacks vs. meals.
    3. Water: 1 litre per day per 100lb body weight.
    4. Protein: A mix of all types including soy, but focus on fish.
    5. Fats: Lean toward flax seed oil vs. deep-fried or fatty red meats, but eat meat!
    6. Fruit: Concentrate on fiber-rich & high-water content vs. sweet.
    7. Sleep.
    8. Vitimins: 1-4g C, 100-300mg B complex, ...
    9. Other: 5-HTP, L-tryptophan, choline (liquid), DMAE, ...
    10. Books: Smart Drugs (dated), Smart Drugs II.
    11. Newsgroups: rec.drugs.smart (watch for scams, group think, and hype...including mine)
    --
    A firewall can not protect you from yourself. Turn off what you do not need. Do not use the firewall to do your work.
    1. Re:Why wait? Here's a starter list... by paxil · · Score: 1

      You are right on with number 1:

      1.Eat less, exercise.

      Following this simple advice will change your life! However, I know that it is very hard to do.

      --
      paxil

  74. mmmm by alleria · · Score: 1

    Rats of NIMH are coming! ;)

  75. Careful engineering by RobertAG · · Score: 2

    There's always a lot of talk about "improving" the human species. But what really would we want to change?

    Let's look at intelligence. Most people tend to focus on that. Do we really want to blindly engineer people with IQs of 150? I've known a number of people who have had PhDs, yet also had the worst interpersonal skills I had ever encountered. One person I knew had a PhD in physics, yet chose to work in retail. A roommate of mine in college carried a 4.0 average in a 5 year mechanical engineering program, but had the personality of a rock and smelled like a goat. On the other hand, I've also known people who barely made it through school, but were the best organizers of people and events. Maybe there IS an inverse relationship between classical IQ and the ability to work in groups. Humanity has advanced though its ability to work in groups. Occasionally, a bright individual appears and influences the group, but this doesn't happen often. The history of civilization is more the story of newer groups standing on the shoulders of the older ones to build newer things. Within humanity, there are people who are best at organizing, there are people who are best at following and there are those who are best at working alone, needing no direction and offering none. These three personalities merge together to give us the humanity we are most familiar with. Humanity is not just a collection of individuals, it is a dynamic, supremely adaptable mass greater than the sum of its parts.

    Are we still evolving? That depends on your point of view. Humanity has left the bush. It's less likely that odd populations will become so isolated as to allow genetic mutations to create new breeds or species of humans. Today's focus in genetics lies in curing diseases. Can we create a smarter person? Quite possibly. Can we force that newly created person to act intelligently? Quite probably NOT. Humans CHOOSE to act stupidly. That act of intelligent decision making requires WORK - and there are LOTS of lazy people.

    When changing the genetic behavior of individuals, the group aspects must be considered.

    1. Re:Careful engineering by tcdk · · Score: 1

      Last I heard most psychologists work width five or six kinds of intelligens (mathematical, social, creative, etc).

      My guess would be that something like the GAP enhancement would enhance you intelligences proportionally to what you where already propositioned to.

      As for the evolution bit: The problem is that the only ways to make evolution work faster are nasty (lots of people dying before they have children), unless we take matters (genetics) into our own hands.

      As what we should evolve into: We do need more brains to solve the problems of today, not "rocket scientists", but people who can understand and solve group problems. Later we'll need real rocket scientists to get some of these fragile eggs out of this basket.

      --
      TC - My Photos..
    2. Re:Careful engineering by reptilian · · Score: 2

      There are 7:

      Linguistic Intelligence, Logical-matematical, Bodily-kinesthetic (think woodworking, etc), Spatial (Architecure and what-not), Musical, Interpersonal, and Intrapersonal (geeks).

      These aren't exclusive. Everyone has all seven, but most people have a specialty, one type of intelligence is much stronger than the others. This fits well with how we evolved...

      We're pack animals. We live in groups, and each person must have a function in that group. Some are leaders, some are workers, and ever since we moved into europe long long ago, some are creators and inventors. This hasn't changed if you think about it. It's just on a much larger scale. The leaders filter to "the top" as politicians and businessmen, the "grunts" stay in the lower classes, building things, hunting domesticated plants and animals to feed the pack, etc., but what makes us different from most other species in this respect (and specifically in this respect) is the other people. They make the tools the hunters use, the shelter they all sleep in. The people we call intelligent, but specifically, strongly intelligent in logical, spatial, and intrapersonal intelligences.

      It's believed this type of person began to appear when we started moving into europe, to adapt to survive the harsh conditions (it was during an ice age remember), and to compete with the Neandrathal. Our bodies weren't adapted to the conditions, so our minds adapted. Linguistic and intrapersonal intelligence was also key, because the sharing of information between "tribes" during this period was very important, but without the "smart" ones to figure out new ways to live, kill, and eat, there wouldn't be anything worth communicating.

      It's also worth mentioning that the artistic didn't appear until about the same time. Homo Sapiens for most of our history weren't that artistic. Once we started moving into europe, from africa (as the prevailing theory believes we did), cave paintings first started to appear. Now, I love looking at psychology from an evolutionary point of view, but for some reason I can't figure this one out. Most of what's been said about that is they'd be used as a teaching tool, to help teach their children about the world before they had to go into it. This makes a lot of sense because the most dangerous time for most mammals would be the time when first venturing from their homes. I'm not sure I like that idea quite as much though because it doesn't seem there was any necessity beforehand. Then again, necessity isn't always what drives evolution. The artists found a niche within our niche, so all the others helped them survive, for providing that service.

      I'm really not meaning to go off-topic; The point is that we don't need to be evolving, though often I wish we would. We live in the same social structure as we always have, but on a huge scale, and with many more specialties. We may even still be evolving our intelligence to become even more specialized. Let's face it, everyone who lives serves a purpose for the rest, whether they're genetically messed up or not. If they had no purpose, they simply wouldn't survive, even today. Some people are meant to be presidents, some are meant to work in fast food. If everyone were mathematical geniuses, the world could not function.

      --

      72656B636148206C72655020726568746F6E41207473754A

    3. Re:Careful engineering by Eviltar · · Score: 1

      It's also worth mentioning that the artistic didn't appear until about the same time. Homo Sapiens for most of our history weren't that artistic. Once we started moving into europe, from africa (as the prevailing theory believes we did), cave paintings first started to appear.

      I don't agree with this point. You seem to be saying that the ability of artistry came to exist when cave paintings came to exist. Cave paintings are the oldest evidence of artistry. Cave paintings aren't artistry, they are expressions of artistry.

      Keep in mind that in order for us to measure the ability you refer to as "artistry", it has to be expressed through some form (in this case, through cave paintings). The invention of cave painting didn't necessarily mark the beginning of artistry; it simply was the first form of expression that preserved well enough for us to discover and measure it much later.

      I believe that there is a good chance that other forms of artistic expression, like maybe dancing and singing (or maybe just humming :), existed before cave painting did. Furthermore, I believe that the ability of artistry existed even before they did.

      --

      -----
      Obviousness is always the enemy of correctness. -- Bertrand Russell
  76. Too late by Mtn_Dewd · · Score: 1

    Its obviously too late... They implemented this technology on me years ago..... =)

    --



    My little sad piece of the internet: www.mtndewd
  77. NMDA Juice by HomeySmurf · · Score: 1

    Now, I assume that ingesting the neurotransmitters would cause them to break down. However, with all the current power juices out there supposedly providing intellectual stimulation, wouldn't it be possible to synthesize this NMDA neurotransmitter and give it to people in injections. Who cares about the mice, as long as it is known to work in humans to increase memory and facilitate learning, then lets get some!

    My idea: since the gene has already been isolated, just put this gene into some common bacterial DNA. The bacteria will produce lots of the stuff, just isolate it somehow (centrifuge, etc), purify and then bottle the stuff. Maybe it will need to be refrigerated and have a short shelf life like insulin, but whatever. It'll still be valuable even if it has to be frozen in liquid nitrogen.

    Now who wouldn't pay for a super drug that actually increases brain power? Use it before cramming for finals, before taking a standardized test, before a technical interview, etc.

    Now the FDA takes forever to approve drugs, and rightly so. However, this is a natural part of the human body, and maybe not so dangerous. Also, put the manufacturing plant in Mexico or Brazil where you can buy all kinds of things like viagra and penicillin over the counter.

    So who's going to go look for venture capital with me. The IPO is in a month and a half!

    --
    "Politics is for the moment, an equation lasts eternity" -A. Einstein
  78. Survival of the fittest by lurker786 · · Score: 1

    I will try not repeat the many good arguments posted previously in the thread.

    You seem to be concerned that "the fittest" are no longer the only ones surviving (and more importantly, reproducing.) I disagree. Totally. Completely. Absolutely. By definition (of course, your definition may be different ;) if you survive you belong to that mythical race of "the fittest". You survived, therefore you are fit to survive. Sure, that is no longer biased (at least in cities) to how good you are at hunting buffaloes with a spear. Because that is no longer a relevant description on "fittest".

    On the other hand you seem concerned about the fact that more people are surviving than previously. How is that a bad thing? That is the point of evolution (sorta). To make organisms better able to survive, reproduce and expand. (On the pessimistic side, you just have to wait for a bit and Malthus will come around. Unless (maybe) we go to the stars...) Also, think information, think entropy, think rich, diverse gene pool.

    Finally (and I guess I repeated more than I intended) think scale. Sure, we appear to not have evolved much in the last few hundred years. Pretty much nothing ever does in that puny timescale. And if you extend your definition of evolution to include more than physical characteristics of the individual (not proper biology, I know,) we *have* evolved to an amazing degree in an amazingly short time.

    -------------------------------------
    The opinions posted do not reflect the opinions of my employer, myself, the poster or Mr. AC. The administration takes no responsability whatsoever for damages. Or anything else.

  79. Re:That's easy! by Beatles · · Score: 1

    PLEASE Moderate this up...it is hilarious!

    Once again man, great post!

  80. Evolution by Anonymous+Shepherd · · Score: 2

    Social selection has been at work on ants, bees, wolves, etc; anything with a social structure where the existence of the structure aids or hurts the survival of the species.

    Look at *sterile* ants, bees, and insects, yet they very much reproduce, evolve, and survive.

    Look at pack/pod/social creatures where some never get to mate, while others get all the eggs. They survive, reproduce, evolve, mate, etc.

    We are no different.

    We have not outsmarted evolution. By it's definition of 'survival of the fittest', anything, social, genetic, or otherwise, that enhance reproduction, survival, and mating, is encouraged, while anything that reduces the three is discouraged.

    Culture can both help and hurt; religions that want people to breed like rabits work in one way. Culture that value quality of living(and less children) push it the other way. Culture that encourage diversity, growth, and success help us, where culture that suppresses it hurt us.

    There are socio-genetic cultural forces that enact evolutionary forces on us. AIDs, birth rates, quality of living, hormones in our food, contaminated environments, diabetes, drugs, etc.

    So to say that 'another form of evolution is at work' now is misleading, because this force has been here from the dawn of time.

    We're just smart enough to minimize the 'natural' process of the more brute force eat/die/mate/breed selection, while encouraging the other more secondary terms instead

    -AS

    --

    -AS
    *Pikachu*
  81. Genius Mice Threaten Humanity! by boss+soul · · Score: 1

    Yes, it's true - super-intelligent mice threaten the very existence of our species. Check out this report for yourself:

    http://www.circling.org/articles/sm artmice.html

  82. make people fast! by Anonymous Coward · · Score: 1

    Unfortunately, this is the real (insidious) reason the Pope has taken such a strong stance against birth control. He sees the influence of the church waning, as the western world becomes richer and better educated, thus more capable of defining their own moral compass, so to speak. The solution? Damn millions of people to lives of miserable poverty by harnassing their natural human impulse for recreational procreation and using it as a weapon against them. A person with many children will be unable to achieve the same prosperity their neighbors enjoy, and will therefore be more likely to become seduced by the same murderous pyramid scheme of religious insanity that repressed their parents and grandparents to the seventh generation. More children = morte tithes = more political influence.

    Disagree? Visit any south american country (including texas). You'll realize the mind-numbing truth, just as I did. The vatican is a scab, a festering scab, that must be lifted from this earth if we are ever to achieve our birthright as a sentient species.

    imuho

  83. Hemos is a mouse. by chocolatetrumpet · · Score: 1

    one flaw in the smart gene: a huge lag.

    --
    Spoon not. Fork, or fork not. There is no spoon.
  84. Evolution and Medical Technology by blueg3 · · Score: 1

    I strongly agree, and think that this is a consequence of today's highly advanced medical technology. No longer are pesky genetic problems (tendency for diseases, congenital defects) a reason to die anymore.

    Now, I'm not saying that I want all of those people that do have these problems to die -- that's just plain immoral. But we have to fact that because we no longer have to compete with each other for survival, then we're not going to evolve.

    If we're not careful, these smart mice are going to just keep on evolving until they seize control of the world from we non-evolving humans. At least I'll be satisfied in knowing that all of these supersmart mice will be using Linux. :-)

  85. Haiku by 575 · · Score: 1

    Intelligent mice
    Now, instead of India
    Outsource to rodents

  86. I don't know... by CaptainSuperBoy · · Score: 1
    I have to say, I don't agree with you at all.. I'd really like to read an actual study that found that 'nerds' children were actually fathered by other men.. doesn't this beg the question, "why are there still so many nerds around?" If the trait of (and this is a blatant stereotype) a smart, well-paid, unattractive and socially inept man was so undesirable, why on earth would there be so many of this kind of people?

    The obvious answer is that there is a significantly lower incidence of 4th of July fireworks injuries in this population.. but seriously, where have you read that IQ is decreasing?

    --

    1. Re:I don't know... by /dev/kev · · Score: 1

      "why are there still so many nerds around?" If the trait of (and this is a blatant stereotype) a smart, well-paid, unattractive and socially inept man was so undesirable, why on earth would there be so many of this kind of people?

      Simple, nerdness isn't inherited. Nerds pop up all over the place, not just as children of other nerds.

      but seriously, where have you read that IQ is decreasing?

      I think he was making it up, following some kind of "logic" to arrive at it from his premises (which were pretty shaky anyway).

      IQ isn't a good measure of "intelligence" anyway, so even if trends of average IQ and so on could be found, I doubt they'd server much real purpose.

      --
      Quidquid latine dictum sit, altum viditur.
    2. Re:I don't know... by cDarwin · · Score: 1
      I read about a pair of blood type studies, one conducted during the Korean war, the other more recently, that found that about ten percent of children were the result of maternal infidelity (IOW, mom was outsourcing). Don't recall where it was. But I'm sure you could find it.

      --

      --

      --
      Socrates was asked where he was from. He replied not "Athens," but "The world."

  87. Already submitted! by TrevorB · · Score: 2
    2000-06-20 00:24:28 Secret of NIMH coming true (articles,news) (rejected)


    And my title was cooler... :) OK, it shouldn't have been classified as news...

  88. I don't think so (Re:Human Evolution) by Punto · · Score: 1
    humans have stopped evolving

    I don't think so.. Sure, it's not the same because we no longer live on caves, and probably people with less education/money (posibilities to actually live longer or better on a modern city) will have more children. But, who controls evolution? There is not a "god" that controls evoluon.. Evolution results from the convination of a lot of factors. So, if we start srewing with ourserlves, thats another factor, a new, and very interesting factor, not seen on other species before.

    Of course, to see actual evolution we would have to wait a _LOT_ of time, at least when it's the result of the known factors.

    --

    --

    --
    Stay tuned for some shock and awe coming right up after this messages!

  89. Propper funding by Neuracnu+Coyote · · Score: 2

    Wonderful! Now all we need to do is procure grant money for the National Institute for Mental Health and give them a few years to be able to bring one of my favorite books as a child to life!

    --
    --
  90. average won't count... by TheDullBlade · · Score: 3

    ...after the next big die-off.

    The bright ones will leave the planet and be free to expand exponentially. The dim-witted ones will be left behind for Malthus to deal with. Once some of our eggs are out of the one basket, I give it a century before Holy Terra goes up in the Holy Fire of the Atom.

    The ways of Nature are harsh, but just.

    BTW, what are breasts made of? Mostly fat. A woman with large breasts and a small waist is well-fed but physically fit (and not pregnant), add in a good set of child-bearing hips, long legs (indicating maturity), and regular facial features (indicating both health and a genetic history of being able to attract the best mates), and you've got an ideal mate. In modern society, large breasts due to implants are also a sign of wealth, something people rarely admit to looking for in a mate, but never turn their noses up at. They are also a sign of willingness to surgically tamper with one's own body for some gain, which may turn out to be a damned adaptive trait in the coming years of cybernetic enhancement.

    --
    /.
  91. no need to be hypothetical by TheDullBlade · · Score: 1

    now let's say that this sterile member tends to become a caregiver that helps the rest of the population survive. Then that strain would have better survival characteristics than a strain without the sterile members.

    Just look at hive insects. Ants, bees, termites, wasps: all mostly sexless workers caring for a breeding female and a few shiftless males.

    --
    /.
  92. I should add .... by taniwha · · Score: 2

    when I posted the original with a score of 1 someone promptly marked it down 'offtopic' - hence my rant - and yeah I was wrong it wasn't Asimov/s

  93. Re:How Does It Affect ME?! by Deosyne · · Score: 1

    Geez dude, pull your head out for a minute and think of the REAL uses for this tech; you get genetically enhanced cat, smarter than hell and make it a deal: it helps you out with a small task and you hook it up with catnip and cheap, easy kittens from the pound for life. You and the smart cat go to bistro, theater, McDuck's, wherever Ms. Portman happens to be spending some time. The smart cat goes and works that cutesy, feline bullshit that cats do on Natalie, she goes apeshit over cat, you rush over, faking loads of concern over the cat's whereabouts and strike up conversation with Ms. Portman without her goons beating the everliving hell out of you for approaching.

    Admittedly, you could attempt this with a regular cat, but given the risk of the cat running to a hairy, fatty named Helga or pissing all over Natalie when the cat runs up to her, you'd better hold out for the enhanced model.

    Deo

  94. Project Einstein by detritus. · · Score: 1

    Brystol Meyers Squibb (subsidary of Mead Johnson) is currently in the development of developing a first of it's kind drug that has been proven to increase baby's IQ's and make them learn quicker. This project has been nicknamed "Project Einstein" and has been kept top secret. It is still in testing (and probably FDA approval), but when it hits the market it will be the first of it's kind for infant intelligence development.

    - Detritus

    "I never really liked computers, but then the server went down on me"

  95. You are missing something by child_of_mercy · · Score: 1
    Humanity ROSE because we help each other.

    Think on that for a second

    Then consider the pack behaviour of most of the more successful species (Lions, even some sharks)

    Then consider the more caring, less callous, nature of the more successful societies on earth.

    Evolution isn't as simple as it seems to fascists.

    --
    'There is a Light that never goes out.'
  96. Mighty Mice by XHero · · Score: 1

    Animal rights people should thanks us for the millions of dollars we as a country have put into improving the genes of mice. If it weren't for us mice wouldn't be able to find the cheese, in those complicated mazes you see everywhere, nearly as fast.

  97. Big confusion!! by renoX · · Score: 1

    Those who have moderated the above posts as insightfull, must think twice.

    1) first point: "evolution takes place on a scale of tens of thousands of years".
    Wrong: see the other replys.

    2) second point: "Bill Gates wouldn't last a week in the savannas where australopithecine thrived; none of them would ever be able to live in a human city".
    On a personnal note, using Bill Gates in this context seems a bit stupid.
    But the real problem here is that you are confusing biological evolution and cultural differences. Take Bill Gates'baby, and send it to the savannas where he will be educated by local tribes (or vice-versa), will he have fewer chance to survive than the other? I'm not convinced. (it works also the other way..).

    As for the final chapter, I have nothing to say :-)

  98. Smart Pets... by Sonicboom · · Score: 1

    If they can train my next dog to
    (a) never sh*t on my carpet (or anywhere in my home)

    (b) always be obediant.

    (c) never to stick his/her nose in one of my dates' crotches....

    hell I might be interested.

    Otherwise, nevermind.

    --
    [Connection closed by foreign host]
  99. And you'd thought that Pinky and Brain were toons by Julian+Morrison · · Score: 3

    How long, I wonder, until we can "uplift" a few other species? Apes, dolphins, dogs, pigs, parrots all seem good candidates. Myself I'd love that; the variety would truly make things interesting.

  100. Survival of the smartest is the case now by cyroth · · Score: 1

    If you think about it for a minuite, why are humans basically rulers of the world?? Because we are able to adapt to our environment through our inteligence. eg we can survive in cold climates because we realise that we can put on warmer clothes or make a fire or heat our houses. If we were to use this breakthrough on ourselves the possibilities for human achievement would be endless. Besides that, how much easier would our lives be if everybody was smarter.

  101. Matrhematical view of evolutionary process by sela · · Score: 1


    Study of the evolutionary process showed a new species is most likely to evolve at the presence of two basic conditions:

    1. The presence of a harsh external environment or a significant change in the environment.

    2. A relatively small, isolated population.

    The theory of evolution is easy to understand when you compare it to math - especially to the evolving of a non-linear system.
    Our mathematic world is the gene space. The enviroment represents the boundary conditions. The genes of each living creature represents a local minima in the gene space. Random mutations are not very likely to take it out of the sink, and new species is not likey to evolve.
    Once there is a change in the boundery conditions (environment), a species is likely to find itself out of the local minimum, or at a shallower sink, which gives an opportunity to a new species to evolve.

    Mutations are totally random. However, the first changes in a population are usually not due to new mutations, but to an increasing frequency of certain genes that where previously scarce in the gene pool of the population. While a larger population have a bigger gene pool, two things are less likely to accur at a large population: the revealing of recessive genes, and the chances to single out winning combinations.

    The reason why the human species is not very likely to evolve into a new one is none of those conditions is likely to occure. First, we are at a very stable local minimum. No reasonable change in the environment is likely to pull us out of the local minimum, because of our ability to adapt ourselves.
    Second, we do not have small, isolated populations. We live in a global world. Each mutation, even a possitive one, will be assimilated in our gene pool, and may lead to more variability, but not to a new species.

    An interesting (and worrisome) question is: can we go backward? If there is no active selection - everyone is "fitting", even the dumber, uglier, weaker persons, are we facing a risk of deteriorating? The reasonable answer is, yes, but only partially. Since we are all around a local minimum, any change make take us out of the local minimum, up to a limit where we do not fit even as humans. The result is: we will still be around the local minimum. Some individuals will be closer, but variability will increase, and the average will be further away from the local minimum.
    So, if we fill the valley (local minimum) of genes, doesn't it mean we may slip out of it, and create new species? Not realy. The reason is "bad" mutations are much more likely than "good" mutations. Each "good" mutation will be assimilated in the general gene pool, and is not likely to create a new species.

    The only change is scattering. If for some reason we will be scattered into small groups, living in harsh environment, the high variability in our gene pool would create differentiations between the different groups, and several new species may evolve rather quickly.
    Could this scattering be also sociological? I don't know. All we can do is wait and see :-)

  102. Re:And you'd thought that Pinky and Brain were too by luckykaa · · Score: 1

    Dolphins would be good;)

  103. Of course it would be applied to humans... by Bodrius · · Score: 1

    That's why the pet industry is so excited.

    --
    Freedom is the freedom to say 2+2=4, everything else follows...
  104. True, but... by FascDot+Killed+My+Pr · · Score: 1

    Evolution IS subtle and I DID oversimplify. But it's even trickier than you've laid out here.

    For instance, your hypothetical 10% sterile strain. Consider each potential mother in the pool: which mother does it benefit to be the one that bears the sterile offspring? None of them. For each mother, they are better off bearing an fertile child. Therefore there is pressure to do so. GIVEN a sterile child there is a way for that child to be useful and contribute to the gene POOL of the SPECIES--but selection happens on an individual (or lower) level. That's why we never see such a thing (except, as someone pointed out, in social insects--who have different mathematical genetics).

    As for "don't have too many children or it will use up the resources": BZZT! Wrong! Genes don't do any long-range planning, let alone allowing for the offspring of other individuals. The effects you see are probably the result of a subtly different cause: The parent evaluates the amount of resources currently available (or likely to be available at birthing time) and has the maximum amount of children that those resources can support. Note that this is different from "don't exhaust the ecosystem" connotation that your "overuse of resources" gives.
    --
    Compaq dropping MAILWorks?

    --
    Linux MAPI Server!
    http://www.openone.com/software/MailOne/
    (Exchange Migration HOWTO coming soon)
    1. Re:True, but... by Reality+Master+101 · · Score: 1

      For each mother, they are better off bearing an fertile child.

      Having children is an important factor, but you're forgetting two other factors: survivability and quality of life. The mothers who produce the infertile caregiver child have potentially better ability to 1) have more children, because they are less likely to die off (since they have more protection, etc), and 2) may have better nutrition for herself and her children because of the food gathering ability.

      That's why we never see such a thing (except, as someone pointed out, in social insects--who have different mathematical genetics).

      I could even argue that we do see this in humans. Why do people live beyond child-bearing age? By your theory, there should be evolutionary pressure to die off as soon as possible.

      As for insects, as far as I know biology doesn't recognize different "mathematics" of genetics and evolution. Insects are "molded" through the same evolutionary forces as everything else.

      As for "don't have too many children or it will use up the resources": BZZT! Wrong! Genes don't do any long-range planning, let alone allowing for the offspring of other individuals.

      Again, you're forgetting about "survivability" as a component of evolution. Let's say I have a population of animals that gets separated into two different valleys. One gets a mutation that causes huge amounts of children to be born. It consumes food faster than it can be replenished through normal growing, and thus it dies out. Environmental equilibrium is an important part of evolution.

      But you don't even need a thought experiment to prove it. Why do a lot of mammals have breeding seasons? By your theory, this should never happen because it should be better to crank out children all year 'round. But it's better to have a breeding season and have children born in the spring because that's when a new season of food has grown.


      --

      --
      Sometimes it's best to just let stupid people be stupid.
    2. Re:True, but... by FascDot+Killed+My+Pr · · Score: 1

      "By your theory, there should be evolutionary pressure to die off as soon as possible."

      "My theory" doesn't say anything like that. It says that the genetic benefit to being STERILE is (usually) overwhelmed by the genetic benefit to being able to reproduce. It says nothing about "clearing the way for future generations".

      "As for insects, as far as I know biology doesn't recognize different "mathematics" of genetics and evolution."

      Well then you don't know enough. Go read a book. Start with "The Selfish Gene" by Richard Dawkins.

      "Let's say I have a population of animals that gets separated into two different valleys. One gets a mutation that causes huge amounts of children to be born. It consumes food faster than it can be replenished through normal growing, and thus it dies out."

      This is true as far as it goes. But look at it from an individual parent's point of view. The question is: "How many children should I have?" The answer is: "If I produce more than my enviro can support, I'm wasting my time because they'll just die." Note that the parent isn't considering environmental impact, just individual short-term gain. So your species WOULD die off--except those members that did the math correctly: they would form a species with different behavior.

      "Environmental equilibrium is an important part of evolution."

      Yes, but not for the reasons you obviously think. "Equilibrium" is the outcome of the sifting and sorting that evolution does. It's not constraint that needs to be "kept in mind"--it's automatically achieved by the mathematics of evolution.

      I highly recommend "The Selfish Gene" and "The Blind Watchmaker" by Richard Dawkins (some of his later books are OK, but not as good).
      --
      Compaq dropping MAILWorks?

      --
      Linux MAPI Server!
      http://www.openone.com/software/MailOne/
      (Exchange Migration HOWTO coming soon)
  105. One Word by FreeUser · · Score: 2

    Willard

    --
    The Future of Human Evolution: Autonomy
  106. The mice just want us to think they're smarter! by David+Raine · · Score: 1

    I don't think this has anything to do with a bunch of scientists. The mice have obviously seen fit to humor this attempt at genetic modification, probably in an odd experiment on human behavior. It's only a matter of time anyway that they show their true form and start taking over the world (the program should be finished by now)... And they're not going to be happy that us humans have been polluting a world that they paid for. I think we should be pouring money into space colonization just in case we decode a message from the dolphins saying "So long, and thanks for all the fish!"

    --

    Dave

  107. Re:Star Wars Gene Engineering by nagora · · Score: 1
    Two Words: Clone Wars.

    Yes, but I don't think they've been defined in the films. Perhaps it is a referance to wars fought with cloned troops, or a cold-war type of war where top diplomats etc. are replaced by clones working for the other side or something like that. AFAIK it's still up to Lucas to tell us what happened; unless I missed something.

    TWW

    --
    "Encyclopedia" is to "Wikipedia" what "Library" is to "Some people at a bus stop"
  108. Why should this ever be a question? by haplo21112 · · Score: 1

    Truth to tell everytime an article like this shows up there is always the question of ethics that gets included, WHY? I really have to ask that! This is a no-brainer(no pun intended) folks, if there is a way to improve humanities lot in life, just do it. Evolution has moved us as far forward as it can. We have one or two break out above average people come along each generation, thats true. Still this really isn't moving us forward as a species. These individuals do pass along their genes, but usually their mate is just another average person. Even when two above average people do get together it many times doesn't make a huge difference as they are just as likely due to the uncertianies of genes to have only average children. Let me offer and example: If evolution were still involved, along with a natural selection, and we were moving forward as a species, we would be talking about the Einstein family and not just Albert. We having(or at least developing) the technology to change our own species fate and lot in the universe have the obligation! to use it. I'd be the first person to volunteer in fact. I have above average intelligence, but I'd love to be able to run faster. Maybe I might someday have a child who can't run at all...I would certianly want everything possible done to change that condition. Our Species no longer has the conditioning factors that allow us to become something greater, we have in fact breed and medicate evolution out of existance.

    --
    Power Corrupts,Absolute Power Corrupts Absolutely, leaving one person(group)in charge is absolutely corrupt.
  109. Inventors Awake by JJ · · Score: 1

    News of a smarter mouse now means that the proverbial ball is back in the proverbial court of the inventors. Human inventors that is simply MUST come up with a better mousetrap to stay ahead in this arms(?, . . . BRAINS) race.

    --
    So long and thanks for all the fish . . . !!!
  110. Pest Eradication by arberya · · Score: 1

    If you laced a few cheese balls with some of this gene therapy, maybe the mice in my house will move out. They will quickly learn that the house is not fit for any animal, human or rodent.

  111. Re:Star Wars Gene Engineering by thetzar · · Score: 1

    The only reference to the Clone Wars in the movies is in ANH, when Obi-Wan give Luke the lightsaber and tells him (the half-truths) about Anakin.

  112. pack behavior by The+Queen · · Score: 1

    Of course we got where we are by helping each other...but if you're going to use the pack animal analogy, I would like to point out that packs will often abandon or even kill their own injured/retarded/sick members.
    Not saying we should go shoot all of Jerry's Kids or anything, but I do agree we could stand a bit of herd-thinning.

    The Divine Creatrix in a Mortal Shell that stays Crunchy in Milk

    --

    The House Between - Original Sci-Fi Series
  113. Old news by Nectar · · Score: 1

    This is very old news. It was reported in Scientific American several months ago (and
    was `old news' at that time).

    Please, can you editors try to stay current
    if you are going to try to lend some respectability to this site by posting science
    stories?

  114. Lawnmower Man? swell... by Vanguard(DC) · · Score: 1

    I get the sense that sci-fi isnt really sci-fi, it's more like time travel. these movies are nothing more than the next millenium's historical fictions... What happens when you get addicted to being "smart"? oh yeah! I know! you switch operating systems! -Vanguard "linux:Braveheart :: Microsoft:Papillion"

    --
    "I think, therefore I get paid."
  115. Smart people....smart mice...smart apes. by Tofu · · Score: 1

    I think we should genetically engineer "smart" apes. It would be great. We could domesticate them and then make them smart enough to do certain tasks that no one else wants to do. They could do yard work. They could be toll booth workers. They could do house work. It would be great. Then , maybe, in the future they would evolve to understand english and eventually overtake the planet.

    And those damn bloody apes would then make us into their slaves!! :) I would not mind Corneilius being my leader though. :)

    --



    Can you see Iron City here?
  116. "Average IQ" by Pseudonymus+Bosch · · Score: 1

    Of course, average IQ is always 100 by definition.

    Do you really have evidence that the quantity of intelligence measured by IQ 100 is actually decreasing? I don't think so.
    __

    --
    __
    Men with no respect for life must never be allowed to control the ultimate instruments of death.
    GW Bu
  117. From hardware to software by Pseudonymus+Bosch · · Score: 2

    The way I see it is that we have substituted genetic evolution by memetic evolution (= culture).

    Just as hardware is less flexible that software (hence the names), genes are less adaptable than memes.

    Science and culture have taken the human species to the Moon and other interesting niches. No species has genetically evolved to reach this (well, some species have evolved to parasite/symbiotize humans (rats, lice, seagulls), and so they follow humankind in our evolution
    __

    --
    __
    Men with no respect for life must never be allowed to control the ultimate instruments of death.
    GW Bu
  118. If you want to read more about this... by vanix · · Score: 1

    ...see "Building a Brainier Mouse" from April's Scientific American. It has a super-cute graphic of a mouse reading Scientific American inside a maze.

    --
    "Government is a disease masquerading as its own cure." --Robert LeFevre
  119. Another good read.. by starman97 · · Score: 1

    Our Neural Chernobyl by Bruce Sterling
    is part of the Globalhead collection of his short stories.

    Hackers get smart gene and put it into a retrovirus which gets loose and infects other species...
    Oops..

    --
    Starman97@Gmail.com (bring it on spammers)
  120. "Beggars in Spain" by Pseudonymus+Bosch · · Score: 2

    Nancy Kress' "Beggars in Spain" (handy, this Google thing) deals with "genetically-bred humans vs. natural humans " and how changing a gene involves other changes in genes and finally in society.
    __

    --
    __
    Men with no respect for life must never be allowed to control the ultimate instruments of death.
    GW Bu
  121. Re:And you'd thought that Pinky and Brain were too by vanix · · Score: 1

    Apes and dolphins, maybe. Dogs and pigs could probably be made a smart as apes and dolphins are now, but parrots? Why, because they seem to be able to talk? There's no way, their brains are waaaaay too small.

    --
    "Government is a disease masquerading as its own cure." --Robert LeFevre
  122. Reproduction of the fittest by __aaedhn419 · · Score: 1

    You realize it is not survival of the fittest, but reproduction of the fittest that determines the fate of a species.

    That may imply that the least fit people are those who produce the least children.

    Put aside your coding and start a family! We're all doomed!

  123. Alien evolution by Rader · · Score: 2
    Have you ever seens the Aliens in shows/movies, they seem to be light colored, large head, small arms, legs, etc. It seems as if the body has shrunk/atrophied and the head got bigger & bigger. And hairless too.

    See, this is the evolution that will happen if we continue to get smarter & smarter, become less & less active. We no longer have to chase down zebras with a spear just to get breakfast. We're not as active. We've lost almost all our hair, since we no longer have to be wooly mammoths to keep warm. heck, just turn the Heater on! And we're losing the hair we have anyways just because of baseball caps (ok, just a theory of mine about hats) Aliens are white, because they don't just program all-nighters, but all-monthers. They don't see the sun months at a time.

    See, just because we don't HAVE to survive Nature's environment doesn't mean evolution has stopped. We now have to survive our Technology environment we created. We'll be flying in spaceships soon, and nature is slowly disappearing anyways due to Yet-Another-Suburb(tm). We're already slowly turning into a society where brains can get you ahead. And even starting to get more and more a MUST. For instance... it used to be a big deal to finish your High School, then it was college. Now everyone goes to college. Soon, it'll be triple PHD, and we've already seen the small small rift in Computer-ese vs. NonComputer users.

    Evolution is happening! Even if we're sociologically morally allowing People with disabilites to live and procreate, and as another poster said, "all the poor people are having 20 kids, so there'll be all these genes with dumb people spreading", blah blah. Yes, see.. that is evolution. Maybe just not in the direction you're thinking of.

    Ok, here's an anology. Let's say that the government made it really cool and easy to get Welfare. Infact, they make it desirable to. (wait, that sounds familiar) Get to watch all the day time crap TV you want! And get payed! So more and more trailer park trash (another poster's words) start to procreate and join welfare. Pretty soon we've got GENERATIONS of Welfare people. See, that's evolution!

    Then! All the money dries up because there were only like 10 of us going to work, and 95% of our money went to taxes. So now all of a sudden there's no longer any Welfare cheese to survive on, and they all start to die because they have the "I-dont-know-how-to-work" gene. Another step in Evolution!

    This actually happened with a certain type of moth in England. All the trees in this region were birch or something (white bark, being the key here). All these moths were white, and could survive because they blended into the white. Well, once in a while, genetics would make a freak, and a black moth was born. Usually he got eaten by the birds, and no more black moths in that family.

    Well, the industrial revolution came for a visit, and spewed forth black soot in the air (and haven't stopped since, i'd wager) Anyway, the trees started to get this darker and darker and darker color to them from the polution. All of a sudden, the freaks of nature that were dark colored moths continued to live and pass their "freaky" gene on, as their white bretheren started to become easy to find on the black trees.

    So the point is, we're all slowly turning into non-action related brainy people. If a catastrophe happened, and we'd all have to haul our fat asses after the zebra to eat, instead of driving to the grocery store, yea, we're screwed. But if this catastrophe doesn't happen, then its ok, because we're creating an environment where it's cool to be an out of shape, porphyric, attrophied, possibly fat, computer geek. Yea

    Rader

  124. Our morality screws our evolution by ferrocene · · Score: 1

    "Now, I'm not saying that I want all of those people that do have these problems to die -- that's just plain immoral." I think that speaks for itself. We are the only species that is moral. Very rarely do mothers and fathers eat their offspring when starving or threatened. It is also rare that females decapitate or eat their mate. If all the other gazelles felt sorry for the slower, fatter gazelles and tried to help them out, they would be screwed. Of course, natural selection and evolution have a lot to do with who their natural enemy is, and either hiding from them (moths that look like tree bark, chamelons, etc) or running away (gazelles, etc) or making themselves poisonous (various insects and frogs) or taking flight, or growing lungs, or mass-producing, etc. Just about every species has devices for this. The thing is, we don't really have a natual enemy, except for maybe disease. We humans only have intelligence and morality. The fact that I'm typing this thought into a computer speaks volumes. My cat doesn't give a shit about this thread and is trying to hunt a bird. He has very keen ears and can notice slight movement in the dark, but he doesn't have a MBA from Harvard (from the dilbert cartoon about ratbert and his external brain pack). Since our only enemy is disease, the only way to fight it is to become intelligent enough to kill it. Or, leave it up to the %5 of us that survive to reproduce like rabbits. Perhaps morality doesn't foster evolution. We can help out our slower, fatter brethren and not have to worry about being eaten. Of course, in a very Shakespearean (sp?) way we lose morality when it comes to large crowds and our own life and death. When someone yells fire in a theater, you'd run over someone's grandmother to get out. And if you're small and weak, yer already screwed. I just saw on VH1 a story about the Who concert where (I believe) 11 people were either injured or killed. Or, if you believe every scene in the movie, Titanic showed how one would rather be labeled weak, inferrior, a pussy, etc just to get in the lifeboat with the women. You'll do anything to survive, it's instinct. So morality only exists when we're all rational.

    --
    Most folk'll never lose a toe, and then again some folk'll...
  125. Here's the scientist's article by Hamburger30 · · Score: 1

    http://www.sciam.com/2000/0400issue/0400tsien.html It's interesting, if a bit technical.

  126. misconceptions about what this result means by luke_ · · Score: 1

    hi, I'm a neuroscience grad student, and I have to comment that basically all of the discussion going on everyone here seriously misunderstanding what this result means. I'm in a hurry, so I can't go into great depth. But to make things simple, the protein they overexpressed in those mice is involved in synaptic modification. So they made mice with more modifiable synapses. The title of the paper is "Enhanced LEARNING after genetic overexpression of a brain growth protein." Learning is not the same thing as intelligence. No one is claiming that anyone made smarter mice except the journalists. The researchers made the brain more modifiable, so the mice could learn a piece of information more quickly. That doesn't mean they could remember it as long, that they could think as well as normal mice, etc. There are a million other factors, but the bottom line is that all they demonstrated was that the transgenic mice were better at a certain task than wild type mice. This could be because they learned faster, or it could be for any number of unrelated side effects (such as ones involving changes in vision). This is like demonstrating that fighter pilots can do some maneuver 95% on cocaine and only 92% normally, and from this extrapolating that it would be beneficial for everyone to install cocaine dispensers that keep them high 24/7. This particular study has no serious implications for evolution or a society of superhumans. The relationship between genotype and brain phenotype is way too complex for anyone to come up with a one-gene solution to creating greater "intelligence." Anything like that will likely involve many genes and large-scale screening of individuals followed by correlations with some measure of the person's intellect, but I won't even start on the problems involved in a study like that...

  127. Compassion does not destroy elimination by DoctaWatson · · Score: 1

    I think there is a definite difference between humanity showing compassion and natural elimination, don't you?

  128. Douglas Adams is right! by warpath · · Score: 1

    Mice WILL be the smartest animals on Earth!

    \//

  129. Intelligence...is just another mutation by Skip666Kent · · Score: 2

    Our ability to modify ourselves through intelligent analysis of ourselves and our environment is really just another mutation. Same as big boobs or a 3rd leg.

    We've been close to our present level of sophistication for what, 2-3,000 years? More maybe? Still just a blink of an eye in terms of the long haul. The last 200 years have seen what looks to be a boiling point of sorts in terms of our ability to modify ourselves and our environment. To what end? Who knows?

    The jury's still out - only Time will tell if this mutation stays or goes!

    --
    **>>BELCH
  130. Re:And you'd thought that Pinky and Brain were too by Julian+Morrison · · Score: 2

    Dogs and pigs could probably be made a smart as apes and dolphins are now, but parrots? Why, because they seem to be able to talk? There's no way, their brains are waaaaay too small.

    I've seen on a TV documentary a parrot able to make such abstract distinctions as "what color?", "which one is metal?", "how many blue?", "which one is square" - getting it right first time, from amongst many objects which differ along all these axes at once.

    The small brain size is confusing, but perhaps running a parrot body doesn't take much processing power, so there's more left over for smarts.