I really hope they solved the 3 issues with their previous attempt: 1. Cost per minute of usage 2. Need for huge antennas (adds to bulk/weight) 3. Massive battery required (makes the phone bulky/heavier).
They need to make the glass lens bigger because I can see the surroundings outside the glasses and it's annoying. Either that or bring the lens closer to the eye. Maybe even contacts?
The supreme court has decided that its up to congress to determine what "limited times" means.. which is really stupid because if anything that's the one thing that judges are for it's for is exercising what's reasonable and what's not. And a hundred years in unreasonable.
Congrats on that. How did you beat stage 4 cancer of the neck? What was the treatment (what were the main drugs).. also how long have you been cancer free.
Can you be a little specific like.. how was it diagnosed and how did they start off the treatment and did they use combination therapy.
Ok so say u got this mindshare to transfer over.. would u want some of the minds to be rotting up the other projects.. considering they didn't exactly push the mysql the way u wanted it to get pushed.. ?
Soon, cancer treatment will be highly specialized and tailored to the individual and the cancer or cancers he/she has. This and other technologies can be used to dynamically adjust the patients treatments in essentially real time. If an emerging resistant strain(s) is detected or found to be emerging, then potent and thought out combination therapy can be used to control or destroy the cancer. Combination therapy will have to be engineered in such a way that it's mathematically as infeasible as possible for newer multi resistant strains to emerge.
Perhaps drugs themselves could test a cell or blood or anywhere in vitro i guess for biomarker(s) and then adjust its structure according to what has been encountered so it can effectively treat it. The simpler thing is so that it tests a cell for a cancer marker first and then blocks or kills it if it is dangeorous.. or it can use multiple criteria. Let me give you an example.. if a certain type of cell.. say in the liver has markers of being kidney origin.. then it could be a cancer cell and the drug can destroy it. This can also be used to treated auto immune problems or infectious diseases. Some progress is being made to this kind of smart drug design.. recently someone announced the can do an AND operation.
Cancer drugs will need to be designed on the fly in the future. As in, if you have a certain cancer, the drug may have to be designed specifically for your cancer based on its genetic profile. What I mean is that they will have to take a sample of your cancer cells, sequence them INDIVIDUALLY.. then figure out what drugs to give you in combination so that all the cancer cells can be destroyed with no chance of resistant mutations survival. In some cases this could mean developing monoclonal antibodies or small molecules tailored only to an individual target or even larger molecules tailored to multiple targets and/or ones hat can collude/coorperate.
There will need to be a mechanism in place for allowing this treatment (require virtual toxicology profiling? Require some animal test? Require the dosage to bbe given in very small amounts first (dangerous & could result in sequential resistance mutations.. that will defeat the combination therapy and make the cancer highly resistant)
How can you state that Physical Review Letters is not a premier physics journal??
PRL is highly respected. Maybe it's ranked 12th overall versus Nature, Science, etc which are not specialized. Also, Robert Wolkow has done well cited stuff in the past.
Are you a physicist?
Just cause you go to some mickey mouse website that supposedly ranks journals that doesn't make it a credible source either.
I was one of those folks who said bad stuff about his posts. If he read it I hope he didn't take it personally. He was a good guy and there's true bad things out there to have gotten riled up about instead. I am saddened by this news.
If we can get fusion energy working cheap, we won't need the climate modeling. Not only that we can build a hundred of these things cheaper with the technology advances.
Climate change is gradual.. the need for new drugs and fusion energy is more pressing.
We know global warming happens, we know how to reduce it. WTF. There is already a wealth of evidence for global warming, whats lacking is political will.. which wasting resources on climate modelling won't bring about.. simple education will.
Bigger payoffs are drug discovery and fusion energy research.
It's a damn shame and should probably even be a crime that manufacturers at the whim of the telcos (all of whom have bribed their way to gaining an unfair government enforced monopoly on communications) go around trying to make it hard for people to install what they like ON THEIR OWN DEVICE.
How can education be fixed when their is a war on critical thinking? Its better for those in power to rule by sound bites, innuendos, and accusations that appear credible enough to be believed.
F u china gvnmt.i rly wld lk to sy mre thn jst ths fw wrds bt th hgh chrgs ar nt afdble. f nly i cld b bl t wrt tht i dsprve ntrly f ths hgh chrgs i wldnt hv 2 b abrvted nd cd say f i hv bn absd or trtred o not. f i cd offrd 2 tll f i hv bn trtrd trst m i wld jst sy t. nywy i wl hv 2 snf nw bcz i m lt fr a prtst mrch in tinman sqr. i shld b bck sn, sry i hd 2 mk ths so shrt. nxt tm i wl c f i cn gt a discnt o nt. i wl c. ltrs bb, bckslsdt.. b th wy, i wt dd u tnk f th btmn mvie? t ws wmsm u rly shldc c t f u gt th chnce. hth ldgr ws gd, i thnk oscr 4 sre, nt jst ot f smpthy. nwy i wl c u ltr, b b, \.
DNA is a effectively a hard wired database where the required data/protein recipes must exist for the cell to work. The cell doesn't just make up new proteins as it goes along unlike a database which can store any combination of data anywhere in any given amount (up the maximum) at any time and said data can be updated or deleted at any given time.
That's not true. Retroviruses for example are quite adept at inserting themselves into a specific location within DNA of a host cell. So yeah, it's possible to insert oneself into a specific location in the DNA. DNA editting/deletion.. that's not a problem.
So are you going to have an infinite number of transcription factors then for every possible piece of data stored in the DNA
No, do you have an infinite number of keys to access your database?
Why infinite?
The transcription factor binds to an address. This is the same as doing a lookup in a database. You always need a key or index to access the data, for example if I want to lookup somebody's phone number.. I need to know their name (otherwise what can I look up?). So what I need is to create a transcription factor that binds to that persons name. In theory the transcription factor to bind to the person's name can get synthesized on the fly in nanoseconds (assuming we can advance molecular synthesis technology to that stage). We don't necessarily need a pre-existing collection of transcription factors, and it can get created by the machine that is searching for the data..the transcription factor recipe doesnt have to be stored in DNA.
What "it's sequential at the base level" have to do with anything? Even in a database once you get to the address of a specifc blob of data.. you need to read off a sequence of characters right.
Unless you mean that to access a specifc data region the DNA must be read sequentially? So if a cell needs to make a protein from say the middle of a chromosome it has to unravel and read through the entire chromosome?
I don't think so.
When a protein is needed, a transcription factor is used that attaches to a specific promoter region address which contains the code for the RNA (protein recipe) it needs to synthesize. The transcription factor has ways of zeroing in on the right location.
After a company I think has battled and flung caustic slander against open source this long.. they even underhandedly boosted the SCO lawsuit in an attempt to carry out a hit on Linux. I'm not going to believe they're suddenly our friends (when the British hired Benedict Arnold, they didn't become patriots).
Let's see them do more, let's see them contribute to the WINE project. Let's see them open source Vista and MS Office.
I believe in forgiveness, but only when the party is genuinely remorseful and truly sorry for their misdeed.
Let's not fall into yet another Microsoft "revenue protecting" trap.
Slashdot Mirror
I really hope they solved the 3 issues with their previous attempt: 1. Cost per minute of usage 2. Need for huge antennas (adds to bulk/weight) 3. Massive battery required (makes the phone bulky/heavier).
They need to make the glass lens bigger because I can see the surroundings outside the glasses and it's annoying. Either that or bring the lens closer to the eye. Maybe even contacts?
The supreme court has decided that its up to congress to determine what "limited times" means .. which is really stupid because if anything that's the one thing that judges are for it's for is exercising what's reasonable and what's not. And a hundred years in unreasonable.
Congrats on that. How did you beat stage 4 cancer of the neck? What was the treatment (what were the main drugs) .. also how long have you been cancer free.
Can you be a little specific like .. how was it diagnosed and how did they start off the treatment and did they use combination therapy.
Did you have a particular genetic disposition?
A foreign company that trades with Cuba has hurdles when trading with the US .. how many cell phone manufacturers don't serve the US market?
http://en.wikipedia.org/wiki/Helms-Burton_Act
Ok so say u got this mindshare to transfer over .. would u want some of the minds to be rotting up the other projects .. considering they didn't exactly push the mysql the way u wanted it to get pushed .. ?
Soon, cancer treatment will be highly specialized and tailored to the individual and the cancer or cancers he/she has. This and other technologies can be used to dynamically adjust the patients treatments in essentially real time. If an emerging resistant strain(s) is detected or found to be emerging, then potent and thought out combination therapy can be used to control or destroy the cancer. Combination therapy will have to be engineered in such a way that it's mathematically as infeasible as possible for newer multi resistant strains to emerge.
Perhaps drugs themselves could test a cell or blood or anywhere in vitro i guess for biomarker(s) and then adjust its structure according to what has been encountered so it can effectively treat it. The simpler thing is so that it tests a cell for a cancer marker first and then blocks or kills it if it is dangeorous .. or it can use multiple criteria. Let me give you an example .. if a certain type of cell .. say in the liver has markers of being kidney origin .. then it could be a cancer cell and the drug can destroy it. This can also be used to treated auto immune problems or infectious diseases. Some progress is being made to this kind of smart drug design .. recently someone announced the can do an AND operation.
Cancer drugs will need to be designed on the fly in the future. As in, if you have a certain cancer, the drug may have to be designed specifically for your cancer based on its genetic profile. What I mean is that they will have to take a sample of your cancer cells, sequence them INDIVIDUALLY .. then figure out what drugs to give you in combination so that all the cancer cells can be destroyed with no chance of resistant mutations survival. In some cases this could mean developing monoclonal antibodies or small molecules tailored only to an individual target or even larger molecules tailored to multiple targets and/or ones hat can collude/coorperate.
There will need to be a mechanism in place for allowing this treatment (require virtual toxicology profiling? Require some animal test? Require the dosage to bbe given in very small amounts first (dangerous & could result in sequential resistance mutations .. that will defeat the combination therapy and make the cancer highly resistant)
Too bad the Leviathan of Parsonstown is not in operation and they let it rot, maybe they'd have been able to track it properly.
http://en.wikipedia.org/wiki/Leviathan_of_Parsonstown
Next time try to carefully read the post you're commenting on before saying something that shows off that you're an idiot.
Dude, that was brilliant. Though some people who didn't read your posting properly won't see what you did there.
How can you state that Physical Review Letters is not a premier physics journal??
PRL is highly respected. Maybe it's ranked 12th overall versus Nature, Science, etc which are not specialized. Also, Robert Wolkow has done well cited stuff in the past.
Are you a physicist?
Just cause you go to some mickey mouse website that supposedly ranks journals that doesn't make it a credible source either.
Agreed.
I was one of those folks who said bad stuff about his posts. If he read it I hope he didn't take it personally. He was a good guy and there's true bad things out there to have gotten riled up about instead. I am saddened by this news.
If we can get fusion energy working cheap, we won't need the climate modeling. Not only that we can build a hundred of these things cheaper with the technology advances.
Climate change is gradual .. the need for new drugs and fusion energy is more pressing.
Why do climate modelling?
We know global warming happens, we know how to reduce it. WTF. There is already a wealth of evidence for global warming, whats lacking is political will .. which wasting resources on climate modelling won't bring about .. simple education will.
Bigger payoffs are drug discovery and fusion energy research.
It's a damn shame and should probably even be a crime that manufacturers at the whim of the telcos (all of whom have bribed their way to gaining an unfair government enforced monopoly on communications) go around trying to make it hard for people to install what they like ON THEIR OWN DEVICE.
Ice wear.
Know eye deed knot.
Maybe now we won't have to hear about him all the damn time.
Don't worry, just cause he's disbarred doesn't mean he can't annoy and corrupt people on TV.
Ok, that was funny .. somebody should say that on TV.
Thank God it wasn't a blackhole malfunction.
Or rather, thank the God particle.
How can education be fixed when their is a war on critical thinking? Its better for those in power to rule by sound bites, innuendos, and accusations that appear credible enough to be believed.
F u china gvnmt.i rly wld lk to sy mre thn jst ths fw wrds bt th hgh chrgs ar nt afdble. f nly i cld b bl t wrt tht i dsprve ntrly f ths hgh chrgs i wldnt hv 2 b abrvted nd cd say f i hv bn absd or trtred o not. f i cd offrd 2 tll f i hv bn trtrd trst m i wld jst sy t. nywy i wl hv 2 snf nw bcz i m lt fr a prtst mrch in tinman sqr. i shld b bck sn, sry i hd 2 mk ths so shrt. nxt tm i wl c f i cn gt a discnt o nt. i wl c. ltrs bb, bckslsdt .. b th wy, i wt dd u tnk f th btmn mvie? t ws wmsm u rly shldc c t f u gt th chnce. hth ldgr ws gd, i thnk oscr 4 sre, nt jst ot f smpthy. nwy i wl c u ltr, b b, \.
DNA is a effectively a hard wired database where the required data/protein recipes must exist for the cell to work. The cell doesn't just make up new proteins as it goes along unlike a database which can store any combination of data anywhere in any given amount (up the maximum) at any time and said data can be updated or deleted at any given time.
That's not true. Retroviruses for example are quite adept at inserting themselves into a specific location within DNA of a host cell. So yeah, it's possible to insert oneself into a specific location in the DNA. DNA editting/deletion .. that's not a problem.
So are you going to have an infinite number of transcription factors then for every possible piece of data stored in the DNA
No, do you have an infinite number of keys to access your database?
Why infinite?
The transcription factor binds to an address. This is the same as doing a lookup in a database. You always need a key or index to access the data, for example if I want to lookup somebody's phone number .. I need to know their name (otherwise what can I look up?). So what I need is to create a transcription factor that binds to that persons name. In theory the transcription factor to bind to the person's name can get synthesized on the fly in nanoseconds (assuming we can advance molecular synthesis technology to that stage). We don't necessarily need a pre-existing collection of transcription factors, and it can get created by the machine that is searching for the data ..the transcription factor recipe doesnt have to be stored in DNA.
What "it's sequential at the base level" have to do with anything? Even in a database once you get to the address of a specifc blob of data .. you need to read off a sequence of characters right.
Unless you mean that to access a specifc data region the DNA must be read sequentially? So if a cell needs to make a protein from say the middle of a chromosome it has to unravel and read through the entire chromosome?
I don't think so.
When a protein is needed, a transcription factor is used that attaches to a specific promoter region address which contains the code for the RNA (protein recipe) it needs to synthesize. The transcription factor has ways of zeroing in on the right location.
http://en.wikipedia.org/wiki/Transcription_factor
http://en.wikipedia.org/wiki/Promoter_site
After a company I think has battled and flung caustic slander against open source this long .. they even underhandedly boosted the SCO lawsuit in an attempt to carry out a hit on Linux. I'm not going to believe they're suddenly our friends (when the British hired Benedict Arnold, they didn't become patriots).
Let's see them do more, let's see them contribute to the WINE project. Let's see them open source Vista and MS Office.
I believe in forgiveness, but only when the party is genuinely remorseful and truly sorry for their misdeed.
Let's not fall into yet another Microsoft "revenue protecting" trap.