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Purdue Unveils a Tricorder

aeoneal writes "According to Science Daily, mass spectrometry is no longer limited to what can be taken to the lab. Purdue researchers have created a device they liken to a tricorder, a handy 20-lb. device that combines mass spectrometry with DESI (desorption electrospray ionization), allowing chemical composition to be determined outside of a vacuum chamber. Purdue suggests this could be useful for everything from detecting explosive substances or cancer to predicting disease. Researcher R. Graham Cooks says, 'We like to compare it to the tricorder because it is truly a hand-held instrument that yields information about the precise chemical composition of samples in a matter of minutes without harming the samples.'"

39 of 177 comments (clear)

  1. Obligatory... by garcia · · Score: 5, Funny

    a handy 20-lb. device

    "He's dead Jim."

    "Well, I dropped the tricorder on his head."

    1. Re:Obligatory... by Anonymous Coward · · Score: 2, Funny

      Now if they could make it for $20, I would buy it.

    2. Re:Obligatory... by Dachannien · · Score: 4, Funny

      On the plus side, if you get involved in any shirtless hand-to-hand combat with strangely humanoid aliens, you won't have to go looking for any styrofoam rocks.

  2. smells like ... the future by chriss · · Score: 5, Funny

    In 1992 Harry Harrison (of SF fame) and Marvin Minsky (of AI fame) collaborated on The turing option, trying to merge Minsky's ideas about how an artificial mind could work with a SF story. Wasn't exactly a masterpiece, but there was an astonishing twist: In the book a brilliant scientist creates the first true AI and embeds it into a sort of fractal robot, whose arms are split into more arms like branches on a tree, ending with thousands of autonomous arms with their own vision each. And the first place this system is used (after being stolen): in agriculture, picking up bugs.

    So I will predict the first mass use of Purdue's Tricorder: Japanese toilets!!!. It can already recognize "biomarkers" in urine, so someone will build a cheap version of it into a toilet and every time you take a dump it will tell you what you should not have been eating, how sick you will be tomorrow and that if you continue that way your insurance won't cover your therapy. It will save the health systems billions.

    .

    Oh, and I'm serious about the toilet part.

  3. pussies by Penguinshit · · Score: 5, Funny

    The research team has used the device to ... identify cocaine on $50 bills in less than 1 second.

    REAL playas use Benjamins to snort blow!

    1. Re:pussies by Prysorra · · Score: 3, Funny

      Where'd they get the cocaine? And it's actually an important point - everything that requires knowing what an material is made of is bound to be used EVERYWHERE.

      .......BEEP BEEP. ....MOM! Why is there broccoli in this??

    2. Re:pussies by rednip · · Score: 3, Informative

      Where'd they get the cocaine? Well, since studies have shown that up to 4 out of 5 circulated bills have traces of cocaine, I'd say that it was fairly easy. However, before you try to smoke your $50s, the amount per bill is very small (16 micrograms).
      --
      The force that blew the Big Bang continues to accelerate.
    3. Re:pussies by AndersOSU · · Score: 3, Interesting

      I had a colleague who was testing out a new mass-spec machine (probably similar to the one in TFA) to verify cleanliness between campains at a plant site. The machine had been developed for use in airports, and the software already contained the profiles for a number of drugs and explosives. Apparently, as the sibling points out, coke is on a lot of our money. Most of the time it is in the ppb level, which could be transfer from money that was with money that was with money that was with coke. Occasionally however a bill would show 100 - 1000x the typical amount, we concluded that those were bills that made it into peoples noses.

      A related note, a lot of money on the also has measurable levels of meth.

      I don't think the point to this how much money is involved in drug trade, but rather how inter-connected out money is, and how good our analytical chemistry techniques are.

      Although... a terrorist would probably be using money that hasn't been in wide circulation - perhaps we could spot them by seeing if too much money any individual is carrying is devoid of drugs.

    4. Re:pussies by mastershake_phd · · Score: 3, Funny

      Although... a terrorist would probably be using money that hasn't been in wide circulation - perhaps we could spot them by seeing if too much money any individual is carrying is devoid of drugs.
       
      What a great logical conclusion. I can just see a politician/cop/prosecutor thinking this. Clean money = terrorist. Dirty money = drug user. Lockem up!

  4. Still waiting for the TNG version by El+Cubano · · Score: 4, Funny

    a handy 20-lb. device

    Must be the ST:TOS version. At 20 lb, I would imagine that a shoulder strap is mandatory wear. Thanks, but I'll wait until the ST:TNG version hits.

    1. Re:Still waiting for the TNG version by Anonymous+Monkey · · Score: 3, Funny

      but the black finish and chrome highlights...It's a classic design.

      --
      We are the Borg...
  5. Take a good look.. by ElScorcho · · Score: 5, Insightful

    Remember what calculators and computers looked like 20 years ago? In a couple of decades we'll be looking at these pictures and laughing ourselves silly at the description 'portable'.

    --
    Evil will always win, because Good is DUMB
    1. Re:Take a good look.. by gardyloo · · Score: 3, Funny

      Insightful. But it can go the other way: Many laptops these days are more like boat anchors. Well, the ones running Vista, anyway.

    2. Re:Take a good look.. by gardyloo · · Score: 4, Funny

      *clarification: Vista does not run well on boat anchors. They really prefer an Aqua interface.*

    3. Re:Take a good look.. by Media+Withdrawal · · Score: 2, Interesting

      Remember what calculators and computers looked like 20 years ago? In a couple of decades we'll be...laughing ourselves silly at the description 'portable'.

      Har, point taken, but you've gotta be kidding about calculators getting smaller. 25 years ago, I bought a Casio scientific calculator for $39. It was nearly credit-card sized and got me through somewhere between 100 and 160 semester credits of science and math, no sweat. I carried it in my pocket for years and only had to change the batteries once or twice. When the keys finally fell out, I could not find a replacement nearly as portable.

      PS: An earlier poster mentioned Harry Harrison, who indeed liked small devices. His Stainless Steel Rat series was full of pinlights and other improbably miniscule, un-ergonomic gadgets.

  6. God damn, reminds me of my "portable" Kaypro by WarlockD · · Score: 2, Interesting

    Not to say it wasn't convent to have a computer with a handle.

    That being said, I wonder how hard it would be to miniaturize this kind of scanning technology. There is a real need for smaller computers, but is there a real need for mass-produced mass spectrometers?

    1. Re:God damn, reminds me of my "portable" Kaypro by rednip · · Score: 2, Insightful

      but is there a real need for mass-produced mass spectrometers? Never get ripped off buying blow again! Yeah!

      Also, the next cop who busts me might find it useful for testing my 'stash' without destroying it. Farmers could do soil tests out in the field. Ambulance crews could use it for quick diagnosis. A school could have one to transfer between the science classes. And of course Homeland security will buy these by the dozen (* as long as there is a couple good Republican donors on the company's board)

      --
      The force that blew the Big Bang continues to accelerate.
    2. Re:God damn, reminds me of my "portable" Kaypro by Original+Replica · · Score: 2, Insightful

      " real need for mass-produced mass spectrometers?"

      Police, airport security, and military applications spring to mind easily. The article did point out that they could detect cocaine residues. Other drugs, and explosives are just as easy I'm sure. I wonder what the range is?

      --
      We are all just people.
    3. Re:God damn, reminds me of my "portable" Kaypro by reverseengineer · · Score: 2, Informative
      I doubt there could be quite as much of a need for smaller mass spec than there is for smaller computers, but I think applications will definitely be found for man-portable mass spec as these devices become smaller and more robust. One of these would allow for rapid trace chemical analysis in the field instead of collecting samples and taking them back to the lab (or to what before counted as "portable," an MS that could fit in a van). I think something like this would be great for lab analysis as well. In the lab I work in, there are only a few mass spectrometers in comparison to a large number of smaller, lower cost detectors like spectrophotometers and refractive index detectors.

      This is because mass spec instruments are large (fairly new benchtop ones aren't nearly 300 pounds like the article states, though- maybe 100 or so) and expensive (hundreds of thousands to millions of dollars) while UV spectrophotometers are comparatively small and cheap (tens of thousands of dollars, and about the size of a toaster oven). Mass spec is also rather complex in its benchtop form- the instrument I work with also requires a gas cylinder and a vacuum pump for operation- and it requires very frequent maintenance to keep working right, particularly maintenance of the electrospray ionization source.

      However, the sensitivity of a mass spec instrument is unparalleled (down to femtograms and attograms of material) and by providing molecular weights and fragment ions, is a huge aid to characterizing unknowns. As an example from personal experience, I've worked with three different methods for the detection of one particular molecule: liquid-chromatography with UV detection, LC with fluorescent detection, and LC-MS. The LC-MS method is at least 100 times more sensitive than the other two. While an instrument like this probably cannot do all the things a high-end instrument can do, it does seem like it could be an attractive option. I can definitely see more and more labs going to mass spec as it becomes smaller, more affordable, and easier to use.

      --
      "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
    4. Re:God damn, reminds me of my "portable" Kaypro by encoderer · · Score: 2, Funny

      "I wonder what the range is?"

      It can go up to 11.

  7. detects explosive compounds by Anonymous Coward · · Score: 5, Funny

    the boston police should be happy about this

    1. Re:detects explosive compounds by shigelojoe · · Score: 3, Funny

      I don't know, I don't think it would be a good idea to send a 20-pound package to the Boston police marked "Warning: Sensitive Electronics".

    2. Re:detects explosive compounds by tchdab1 · · Score: 3, Funny

      >>the boston police should be happy about this

      Why, does it also detect portable lighting displays?

    3. Re:detects explosive compounds by Lord+Ender · · Score: 4, Funny

      the boston police should be happy about this


      Sergeant: Sir, according to this device, the cartoon character is made of plastic. If I remember my extensive training at community college correctly, bombs can be made of plastic explosives. I recommend we shut down the city and destroy all the cartoon characters at great expense to the taxpayers.

      Mayor: Sergeant, why waste all the taxpayer's time and money on a few lamps?

      Sergeant: Cause fuck em, that's why.

      Mayor: Excellent.

      --
      A slashdotter who didn't build his own computer is like a Jedi who didn't build his own lightsaber.
  8. IGEN Tricorder released in 2000 by Anonymous Coward · · Score: 5, Informative
    IGEN (now called Bioveris) is a biotech in MD that licenced the Tricorder (R) name from Paramount for their product. PDF list o products

    and it detects

    • E. coli
    • Salmonella
    • Listeria
    • Cryptosporidium
    • Botulinum Neurotoxin A & B , E & F
    • Staph A
    • Staph B
    • Ricin
    • Anthrax
    1. Re:IGEN Tricorder released in 2000 by Dunbal · · Score: 2, Funny

      What does a viola have to do with anything?

            It's how drunk Frenchmen say "voila"...

      --
      Seven puppies were harmed during the making of this post.
  9. Re: The Island by prakslash · · Score: 2, Informative

    Interestingly, the "toilet tricorder" was shown in the 2005 movie "The Island" starring Ewan McGregor. The toilet detected too much salt/nitrates in the urine and restricted him from eating bacon.

  10. The weight by hack++slash · · Score: 5, Funny

    After carrying one of those around all day with a shoulder strap you'd welcome a Vulcan nerve pinch to ease the pain.

    --
    To do something right, you often have to roll up your sleeves and get busy.
  11. Very clever by bendodge · · Score: 2

    This does indeed have enormous potential. But - how many million does it cost?

    --
    The government can't save you.
  12. Looks like a... by Anonymous Coward · · Score: 3, Funny

    Spock: It looks like a toaster Jim.
    Jim: Spock...what's a toaster?
    Spock: It was a early 21st century tool for draining primitive power sources.
    Jim: Why would they need such a tool?
    Spock: The existence of such a tool defies logic Jim.
    Dr. McCoy: YOU VILE EARTH BASHING VULCAN. Everything that was made by pre-space fairing human defies logic.
    Dr. McCoy: I was used to prepare food, YOU POINTY-EARED AUTOMATON.

    Jim: Oh look...toast

  13. Re:Anyone know anything about these? by sokoban · · Score: 3, Informative

    A mass spectrometer needs to be a certain size since it ionizes a molecule to break it into smaller pieces and then passes them through a magnetic field. The charge (of the ion fragments) interacts with the magnetic field to cause the path of the fragment to bend. The radius of the curvature of the deflection is correlated to the mass/charge ratio, thus the mass spectrometer will tell how massive the fragments are. By knowing the mass of the fragments, the formula and structure of the compound can be elucidated by using a few tricks based on the isotopic abundance of elements in the earth.

    Wikipedia has a pretty good article and diagram.
    http://en.wikipedia.org/wiki/Mass_spectrometry

    --
    09 F9 11 02 9D 74 E3 5B D8 41 56 C5 63 56 88 C0 is the magic number.
  14. Re:Anyone know anything about these? by Dunbal · · Score: 2, Insightful

    why do these things have to be so large in the first place. Anyone in the know point me to a good explanation of how these work?

          Here for some vague info on how a spectrometer works. Basically you have to turn the stuff to gas (so you need a heating unit), then you have to ionize it, then you shove the whole lot into a magnetic field of known strength.

          Since the degree of deflection of a particle when it passes through the magnetic field is proportional to a) charge and b) mass of the particle, what you end up measuring is a series of peaks at certain points on a graph. This info (when compared to charts of known compounds) lets you know the composition of the substance you tested. That's the way it was at the beginning.

          Then someone said why don't we just stream the particles from a homogenized sample, and vary the strength of the magnetic field. That way we simplify our detection part of the equipmet.

          This is a very general idea of the principles, obviously you could spend years learning all the techniques, and I haven't been in a lab for a while. At the beginning all we could work out was the types of elements involved in a compound, and empirical formulae. The separation and ionization techniques have been refined somewhat, and now we can compare different molecules instead of atoms, which helps a great deal in figuring out what we're looking at.

          Getting back to your question, the unit invariably has to be a bit bulky since you need a) a powerful magnet and b) an adequate distance to "catch" all the particles you are interested in.

    --
    Seven puppies were harmed during the making of this post.
  15. Re:I've been wondering... by Anonymous Coward · · Score: 2, Interesting
  16. Actually, this is not the first... by Flailmonkey · · Score: 3, Informative

    While it is a new design, and has different features, this is in fact not the first tricorder that has been made.

    http://www.stim.com/Stim-x/0996September/Sparky/tr icorder.html talks about the very first "tricorder," but it doesn't look like it was very successful. Maybe Purdue's device will stick around longer.

    By the way, something that is very interesting to note is that Gene Roddenberry allows anyone who creates devices like the ones in Star Trek (and presumably its variations) can use the names used in the show. Get to work all you Trekkie engineers!

  17. OK, but .. by BigLug · · Score: 2, Interesting

    ...allowing chemical composition to be determined outside of a vacuum chamber. Purdue suggests this could be useful for everything from detecting explosive substances or cancer to predicting disease.
    OK, but if we use this, can we get the chemical composition of Coke or KFC? From there, we should be able to determine the recipe or the 11 Secret Herbs and Spices .. right?
  18. First use will be military, second law enforcement by AHumbleOpinion · · Score: 5, Insightful

    So I will predict the first mass use of Purdue's Tricorder: Japanese toilets!!!. It can already recognize "biomarkers" in urine, so someone will build a cheap version of it into a toilet and every time you take a dump it will tell you what you should not have been eating, how sick you will be tomorrow and that if you continue that way your insurance won't cover your therapy. It will save the health systems billions.

    The first use will be counterterrorism/counterinsurgency, the second law enforcement. In the law enforcement context they will analyze the air around you when they stop you to chat, pull you over, etc. The molecules leaving your body/clothing/car will enter the public domain atmosphere and be fair game for analysis. It think there is precedent from having dogs sniff the exterior of a car at a border crossing, the pot smell entered the public domain, the trained dog signaled, instant probably cause for a search. Similar justifications will be safety related. "I need to interview you, but first for your safety and mine, I need to scan you."

  19. No wireless. Less space than a nomad. Lame. by Anonymous Coward · · Score: 2, Funny

    a handy 20-lb. device

    No wireless. Less space than a nomad. Lame.

  20. Re:You're not going back far enough by Media+Withdrawal · · Score: 2, Interesting

    30 years ago, a simple +-*/ calculator was easily twice the size of today's standard calculators.

    Yes, yes, and the ENIAC was bigger still. We all know that technology generally advances if you look at long enough stretches of time. What's not obvious to the young, though, is that this change is not smooth, uniform and linear like their coursework, but choppy, multiplex and shaped by random social and market forces. "Two steps forward, one step back" has left a hell of a lot of good design buried in the dustbin of history---the tiny Casio included. Its short tenure was not a simple overshoot of a size optimization problem. Who's to say it wouldn't succeed now that science and engineering include many more people with small fingers, pockets and handbags (i.e. girls, women, people from developing countries)? The longer you work in technology (especially design), the greater the chances that you'll profit by unearthing some of the treasures buried in the archeology of your own field. The past isn't just for dissing.

  21. Re:First use will be military, second law enforcem by rpbird · · Score: 2, Informative

    Nope, not unless the Supreme Court is overthrown. They ruled several years ago in a case involving the police use of FLIR to spy on the houses of suspected pot growers, that the use of remote sensing equipment without a warrant is a violation of the "Unwarranted Search" clause of the Bill of Rights. The cops tried to use the "plain sight" exception, but since we don't see in infrared, the court wasn't having any of it. I think the tricorder would fall under this ruling. Using a tricorder without the express permission of the suspect would be a similar violation.

    Though this does bring up an inconsistency. As you pointed out, US law does allow for the use of dogs to detect drugs. Or does the officer have to get permission to use the dog? Not having smuggled drugs, this is an area I'm woefully ignorant in.

    I am not a lawyer, nor do I play one on TV.