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Scientists Developed Artificial Structures That Can Self-Replicate

First time accepted submitter mphall21 writes "New York University scientists have developed artificial structures that can self-replicate, a process that has the potential to yield new types of materials. In the natural world, self-replication is ubiquitous in all living entities, but artificial self-replication has been elusive. The new discovery is the first steps toward a general process for self-replication of a wide variety of arbitrarily designed seeds."

127 comments

  1. Another step by mysidia · · Score: 3, Interesting

    Towards Grey goo.

    Or big nations making mechanical viruses as weapons, and ultimately... those creations at risk of being turned against their creator through malfunction, hackers, or worse.

    1. Re:Another step by Anonymous Coward · · Score: 0

      My initial reaction was, "How many comments before a grey goo mention?" Well met, sir.

    2. Re:Another step by ihaveamo · · Score: 4, Insightful

      Already happened. Except it's pink goo. And it's us.

    3. Re:Another step by interkin3tic · · Score: 3, Insightful

      And you getting a better computer is just one more step toward skynet.

      Or big nations making artificial intelligence as weapons, and ultimately... those creations at risk of being turned against their creator through malfunction, hackers, or worse.

      Slashdot: news for technophobes. Lay off the LSD. Every technology can be abused. You're suggesting we shouldn't look into self-replicating structures because one day far down the road, some evil government agency MIGHT use it to unleash a horde of nanobots which will destroy the world? That's absurd.

    4. Re:Another step by satuon · · Score: 1

      Hate to disappoint you, but they're using DNA for the self-replication part, so no mechanical viruses, only organic.

    5. Re:Another step by Oxford_Comma_Lover · · Score: 3, Insightful

      The greater concern is that the technology will be used without understanding of the consequences. The Replicators in Stargate, for example, emerged from an experiment in which a childlike intellect taught its toys to make more of themselves. Research into self-replication, while reasonable, is not without nightmare scenarios or significant potential drawbacks.

      The cockroach is one example of such an experiment. Who is to say that in time, we will not create an example capable of out-competing us for some natural resource? So it is not without risk to experiment in self-replication. You can limit the risk, of course. Until someone makes the wrong kind of mistake at the wrong time. Kind of like researching Level 4 biohazards in a major population zone. If nobody does something dumb or protocols require fifty dumb things to happen at once for a problem and no massively unexplained events occur, it works just fine.

      --
      -- IANAL, this isn't legal advice, and definitely isn't legal advice for you. Also, Squee!
    6. Re:Another step by Archangel+Michael · · Score: 1

      This is the same as the story of the Golems , so nothing new.

      --
      Agent K: A *person* is smart. People are dumb, stupid, panicky animals, and you know it.
    7. Re:Another step by Anonymous Coward · · Score: 0

      I suppose it could be said that we've turned against evolution. Kinda. If you twist things around a bit. Evolution's not really a creator, though, it's more of a process.

    8. Re:Another step by Anonymous Coward · · Score: 0

      Being outbred by people you regard as inferior does not mean we've turned against evolution.

      Evolution, like you say, is a process. It doesn't have an opinion. It doesn't have a goal. Humans will keep evolving, and each generation will be a little bit better adapted to survive and breed than the last. Your opinion on the way that happens is irrelevant.

    9. Re:Another step by EdZ · · Score: 2

      Or rather, it's green goo (with life by volume being predominantly chlorophyll-using). Note how the entire planet has not become a single lump of homogeneous cells. Considering why this is will quickly tell you why the Grey Goo scenario is rather silly. If there is any danger from unrestricted replication, it would be more akin to the introduction of a foreign species into an ecosystem. However, unless whoever builds aforementioned unrestricted (and pointless: unless the replicator itself is useful, why would you design it to only replicate more of itself rather than making something useful?) replicator designs it almost entirely out of Carbon, Hydrogen, Oxygen and Nitrogen, it would either be bought to it's knees without freely available Silicon and rare-earths, or simply not compete with organic life and form a parallel ecosystem.

    10. Re:Another step by Anonymous Coward · · Score: 0

      "Already happened. Except it's pink goo"

      Racist!

    11. Re:Another step by goarilla · · Score: 0

      Evolution, like you say, is a process. It doesn't have an opinion. It doesn't have a goal. Humans will keep evolving, and each generation will be a little bit better adapted to survive and br ed than the last. Your opinion on the way that happens is irrelevant.

      This is not completely true, evolution doesn't have an endgoal like your reply seems to imply.

    12. Re:Another step by ancienthart · · Score: 2

      Except that StarGate is fiction.
      It'd be a pretty shitty story that went "Thousands of years ago, a civilisation created a self-replicating machine. It escaped into the environment. And was promptly turned back into raw silicon dioxide by the first bacteria that found it tasty."

    13. Re:Another step by ericartman · · Score: 2

      Ugly bags of mostly water

    14. Re:Another step by hvm2hvm · · Score: 1

      It has a rule that describes the way it works, not a purpose

      --
      ics
    15. Re:Another step by skids · · Score: 1

      Kind of a leap from the OP. Also pretty wrong, in that a species that can edit its own genome in a conscious process has surpassed evolution, and we are pretty much there.

    16. Re:Another step by BJ_Covert_Action · · Score: 1

      It is always amazing to me when folks are willing to hold up a piece of fictional art to contest a15,000 year old (how long have modern humans been around exactly?) historical trend. We've been developing earth-shattering technologies that could be used to royally obliterate ourselves for awhile now. Think about it, designing a metallic blade that could, literally, break every other blade wielded against it back during the various transitions from stone-age to bronze-age probably convinced many of the folks at the time that the individual wielding the metallic blade was all but invincible. And yet, somehow one metal blade wielding psychopath didn't conquer the whole world (though, some tried).

      Technology breakthroughs have been occuring for thousands of years. The nuclear bomb, dynamite, machine guns, rifles, muskets, long bows, hell, even something as simple as putting a rotten corpse on a catapult and flinging it at your enemies could be considered technology. We've managed not to kill ourselves yet.

      Does this new technology have the potential to destroy the human race? Maybe it will eventually, but so have a dozen other inventions throughout history. One badass, epic science fiction T.V. series is not an adequate bit of evidence to hold up and dispute this trend.

    17. Re:Another step by davewoods · · Score: 1

      Technology breakthroughs have been occuring for thousands of years. The nuclear bomb, dynamite, machine guns, rifles, muskets, long bows, hell, even something as simple as putting a rotten corpse on a catapult and flinging it at your enemies could be considered technology. We've managed not to kill ourselves yet.

      Well sure, but keep in mind, we only have to end the Earth once in order for it to all be over, I am sure that at some point that will happen. SOMEONE has to get "Red button that kills everyone"-happy eventually, it happens all the time in movies.

      I am sure everyone in charge of anything that could possibly escalate into "Grey goo" is keeping a close eye on not letting it go too far.

    18. Re:Another step by Un+pobre+guey · · Score: 1

      No, we're not. Far from it.

    19. Re:Another step by interkin3tic · · Score: 1

      The Replicators in Stargate, for example

      Going to stop you right there. That's not an example of anything other than how technology destroying the earth is a common THEME IN SCI FI.

      The cockroach is one example of such an experiment.

      What.

      Who is to say that in time, we will not create an example capable of out-competing us for some natural resource? So it is not without risk to experiment in self-replication.

      You can't assume all possibilities to be likely just because of how dire they would be. Who is to say that by getting out of bed, you will not be exposed to a flu, and it will recombine with some bits of your genes, and create a world-ending superflu? No one, because it's possible. Extremely unlikely, but possible. With replicators, how about we wait until there is some technology which has a reasonable chance of causing grey goo? You know, take the rational approach that has worked with ALL OTHER TECHNOLOGY UP TO THIS POINT.

    20. Re:Another step by Oxford_Comma_Lover · · Score: 1

      I didn't say Stargate was evidence. The evidence was the cockroach. The possibility of outcompeting for resources is the most likely concern. The fiction merely illustrates it.

      And yes, all of those things were technology. Alexander the Great (the corpses) invented biowarfare in that way, but nobody thought it would destroy the world--it didn't have the potential to yet. Today, it can be pretty gruesome. Machine guns had a huge cost--world war I had many more casualties because of them. Other technologies were very useful while being destructive--the infantry revolution helped incentivize the movement toward popular government, for example.

      And we haven't destroyed ourselves--not with nukes, and not even (yet) with Global warming. And not with (malicious) genetic engineering. But all of those things are possible paths to massive destruction, as is the creation of one or more self-replicating species/objects that outcompete us. It only has to happen once. I'm not saying we shouldn't build--I'm saying we should build prudently.

      --
      -- IANAL, this isn't legal advice, and definitely isn't legal advice for you. Also, Squee!
    21. Re:Another step by Oxford_Comma_Lover · · Score: 1

      Cockroach. Good survivor. Self-replicating.

      --
      -- IANAL, this isn't legal advice, and definitely isn't legal advice for you. Also, Squee!
  2. Project Genesis by Nom+du+Keyboard · · Score: 1

    And no doubt it will be called (wait for it) Project Genesis.

    --
    "It's the height of ridiculousness to say for those 9 lines you get hundreds of millions."
    1. Re:Project Genesis by Empiric · · Score: 1
      --
      ~ Whence do you come, slayer of men, or where are you going, conqueror of space?
  3. Good news... by GuJiaXian · · Score: 5, Funny

    ...they've created an artificial structure that can self-replicate. The bad news is that it's Ice-9.

    1. Re:Good news... by Ihmhi · · Score: 1

      Quick, somebody call Colin Farrell!

  4. Uh oh by Hsien-Ko · · Score: 2

    If this thing self-replicates to resemble a Robert Patrick, we're all screwed.

    1. Re:Uh oh by Circlotron · · Score: 1

      I for one would like to welcome our self-replicating overlords.

    2. Re:Uh oh by Fnord666 · · Score: 3, Funny

      I for one would like to welcome our self-replicating overlords.

      Especially if they look like Kristanna Loken

      --
      'The tyrant will always find pretext for his tyranny.' - Aesop's Fables
    3. Re:Uh oh by PopeRatzo · · Score: 2

      Especially if they look like Kristanna Loken

      The Academy snubbing her for an Oscar for her amazing performance in Uwe Boll's 2006 epic In the Name of the King (Dungeon Seige) is a travesty that I still have not gotten over. They gave it to that boring Helen Mirren for The Queen that year, and while Helen Mirren is decent, and certainly bangable, she doesn't have Kristanna Loken's acting chops. However, I understand Mirren can pick up quarters with her...you know, so I can see how the Academy might be swayed.

      Regarding the self-replicating structures, affiant sayeth not.

      --
      You are welcome on my lawn.
    4. Re:Uh oh by tehcyder · · Score: 1

      The Academy snubbing her for an Oscar for her amazing performance in Uwe Boll's 2006 epic In the Name of the King (Dungeon Seige) is a travesty that I still have not gotten over.

      That film's got Jason Stathan, Ray Liotta and Burt Reynolds in it too. Seldom can so much ham have been gathered together in one place.

      --
      To have a right to do a thing is not at all the same as to be right in doing it
  5. self-replication is easy... by catbutt · · Score: 2

    ...if you are allowed to have complex raw materials.

    Fire self replicates. Fallen-down dominoes self-replicate. The line between "chain reaction" and "self replication" is very blurry.

    1. Re:self-replication is easy... by Co0Ps · · Score: 3, Interesting

      Yes.. your argument applies to literally everything though... so dismissing anything as "just a chain reaction" is basically saying that "this is just a subset of the universe." In other words your argument is true but pointless. Disclaimer: I assume that the universe is a deterministic state machine.

    2. Re:self-replication is easy... by Kozz · · Score: 4, Informative

      ...if you are allowed to have complex raw materials.

      Fire self replicates. Fallen-down dominoes self-replicate. The line between "chain reaction" and "self replication" is very blurry.

      I don't think it's as blurry as you'd make it out to be. Fire and falling dominoes are instances of entropy , quite the opposite of what these scientists are after, I believe.

      --
      I only post comments when someone on the internet is wrong.
    3. Re:self-replication is easy... by vajorie · · Score: 1

      a deterministic state machine.

      which is in all honestly quite pointless.

    4. Re:self-replication is easy... by artor3 · · Score: 1

      Everything is entropy. Self-replicating machines included.

    5. Re:self-replication is easy... by Jane+Q.+Public · · Score: 2

      "which is in all honestly quite pointless."

      What's your point?

    6. Re:self-replication is easy... by Jane+Q.+Public · · Score: 2

      What the other poster said. Exactly. Self-replication, the seeming creation of greater complexity out of less complexity, is only possible in open systems, that can get information or energy from elsewhere.

      The universe, being (as far as we know) a closed system, therefore, can only allow it in relatively small and isolated regions, precisely because of entropy. Local entropy can go down (self-replication) but inevitably it adds to the overall entropy of the universe.

    7. Re:self-replication is easy... by Kozz · · Score: 1

      Everything is entropy. Self-replicating machines included.

      Really? Everything? So then, order and disorder are just a matter of opinion? Well, let's put down our books and get in line for the local megachurch.

      --
      I only post comments when someone on the internet is wrong.
    8. Re:self-replication is easy... by benjamindees · · Score: 1

      Even self-replicating machines can only represent local order. So what you view as "self-replicating" or not depends on the scale at which you examine it.

      --
      "I assumed blithely that there were no elves out there in the darkness"
    9. Re:self-replication is easy... by artor3 · · Score: 1

      I don't know what church has to do with anything. The laws of thermodynamics are abso-fucking-lutely clear that no process can decrease the total entropy in a system. That includes self-replication. The machines will inevitably give off waste heat or break down complex materials. That's grade school level stuff. Perhaps next you'd like to bitch at me for asserting that the world is round?

    10. Re:self-replication is easy... by radaghast · · Score: 1

      delta(G) = delta(h) - Tdelta(S) is the equation you are talking about I guess.

      Clearly the entropy of a system can be decreased during a spontaneous process if it is exothermic enough. I see you do refer to it giving off waste heat, which is necessary, but that's not the same. As far as I know cosmologists have not determined the source of order in the universe, and so you cannot say that heat is just an abstraction of entropy.

    11. Re:self-replication is easy... by Anonymous Coward · · Score: 1

      Yes, but self-replicating machines (and life) increase the _local_ order of the system (e.g. the number of states in which a self-replicating machine exists is much smaller than all possible states of components) while increasing the entropy of the surrounding environment.

      The end-products of fire, falling dominoes, etc., are _locally_ less ordered than the fuel consumed. E.g. carbon ash and smoke are less ordered than pieces of wood or not-fallen dominoes. That's easy to see -- there are more ways to arrange fallen dominoes than there are to arrange standing dominoes.

      That's what separates simple chain reactions from li

    12. Re:self-replication is easy... by johanatan · · Score: 1

      The universe, being (as far as we know) a closed system

      The problem is that we don't know very far. There is convincing evidence that the cosmos is a house of mirrors and thus finite and closed. See: 'topological lens effect.'

    13. Re:self-replication is easy... by astar · · Score: 1

      Contemporary science has various sources of truth. A common one is experiment. Now the way thermodynamics is demonstrated experimentally, well, half a century ago, is to put the test system in a box, let it get to stable equilibrium and measure whatever goes in and out. So far so good?

      Okay, the other thing science gets its truth from is some sort of religious thingy. If you say the universe is going to some sort of heat death hell, then just how are you going to talk about putting the universe in a box and then standing outside it? I am not sure that this even a issue of practice, but of meaning.

      And time scale issues are wonderful. Do you really want to say the surface of Earth is in stable equilibrium?

      Oh, I know, there is always someone fiddling with "almost, but not quite" stable equilibrium. That has been going for a long time. Looks like it is an intractable problem.

      What else. You recall I mentioned measuring "something" going in and out. If you change the meaning of "something", then you are making a deep change in the meaning of the inviolate thermodynamic laws. And applying the laws to themselves, did this just violate the laws? Of course not, except most scientist types like to think funny things about the domain of applicability of that with which they work. See "religion". And realizing that, yes, the thermo laws just got heavily violated. :-) Of course, if the universe is a deterministic state machine I retreat off stage! I really do personally think that machines obey these sort of laws. And the question of whether you, part of the universe, are a machine or not is, of course, religious, which ever side you chose.

      Ah, I am using a broad definition of "religious" Who was it who said "I am really very spiritual, but I am not a believer ..."? And I am using an odd definition of machine too.

      but enjoy as you can

      enjoy

    14. Re:self-replication is easy... by GerryHattrick · · Score: 1

      Those examples increase entropy. 'Self-replication of materials' must DEecrease enrtopy. Ergo, you need an energy input to a process designed or evolved to do the replication. It won't just 'go out there and do it'.

    15. Re:self-replication is easy... by julesh · · Score: 2

      Life is an example of negative entropy, i.e. a process that absorbs free energy from its environment and uses it to work against entropy by making a small section of that environment more ordered. That the absorbtion of energy creates more entropy than the localised reduction is given, but it doesn't detract from the usefulness of this observation. I imagine any realistic self-replicating machinery will have the same attributes. Fire and falling dominoes, however, don't.

    16. Re:self-replication is easy... by Jane+Q.+Public · · Score: 1
      My words:

      "The universe, being (as far as we know) a closed system..."

      Your words:

      "There is convincing evidence that the cosmos is a house of mirrors and thus finite and closed."

      I fail to see where there is disagreement here.

    17. Re:self-replication is easy... by Anonymous Coward · · Score: 0

      Perhaps next you'd like to bitch at me for asserting that the world is round?

      Round? No
      Oblate Spheroid? Yes

      /pendantic

    18. Re:self-replication is easy... by mooterSkooter · · Score: 1

      re: order/disorder/opinion

      I've often wondered about this: If a pile of stones are randomly thrown on the ground, they have a high entropy yes? What I place them carefully in a pre-determined (but identical to the 'random' version earlier) configuration directly on the ground? Surely one has high entropy and the other has low entropy - yet they're identical!

      Replace stones with some tiny molocules if you want.

      I'm obviously missing something obvious.

    19. Re:self-replication is easy... by Anonymous Coward · · Score: 0

      Citing Prof. M.C. Hawking, it is only in a closed system that the entropy must rise.

    20. Re:self-replication is easy... by YouDieAtTheEnd · · Score: 0

      I believe he was taking issue with you saing that everything is entropy, not that systems tend towards entropy. Using your second assertion 'the world is round'; if we put your first assertion into the same terms, it is as if you said 'everything is round' rather than 'matter tends towards roundness'.

    21. Re:self-replication is easy... by YouDieAtTheEnd · · Score: 0

      The idea of entropy is not so much related to the instantaneous location of elements within a system but in the change in location (distribution) over the course of time. More importantly it is concerned with the availability of energy within the system to do work. If we take your example of scattered stones and apply what we've said, we can see that the system would have low entropy if you placed the stones in such a way that they form a desired structure, say the wall of a house for instance. The wall performs work by doing things such as holding up a roof or keeping the wind out. The entropy of our wall system will increase over time as the stones are moved from their original positions by natural forces. This weakens the ability of the wall to do the work it was designed for. If enough of the stones move far enough then the wall loses it's ability to act as a wall and will collapse.

    22. Re:self-replication is easy... by Chris+Burke · · Score: 1

      So what you view as "self-replicating" or not depends on the scale at which you examine it.

      Yeah, at the scale at which the self-replication is occurring, it's self-replicating. :P

      These molecules are self-replicating. The parent they are present on is not. This is not exactly a deep insight.

      --

      The enemies of Democracy are
    23. Re:self-replication is easy... by Chris+Burke · · Score: 1

      s/parent/planet/;

      --

      The enemies of Democracy are
    24. Re:self-replication is easy... by Chris+Burke · · Score: 1

      Well if you're going to be pedantic, oblate spheroids are round. So are eggs. Spheres are round, too, but spheres are not the only round object.

      The world is oblate spheroid-ish, and thus round.

      --

      The enemies of Democracy are
    25. Re:self-replication is easy... by mooterSkooter · · Score: 1

      AAh, that makes more sense. I was getting confused because my science teacher used the tidy house analogy at school. If no energy is put into the system (the house), then it's gets messy or high entropy...and I always use to think that I could get it in the same state by purposely making it messy but of course that would require me putting energy into the system.

      Sorry, I'm no physicist!

    26. Re:self-replication is easy... by Chris+Burke · · Score: 1

      Surely one has high entropy and the other has low entropy - yet they're identical!

      The entropy is the same. It doesn't matter how they got in that state. Deliberately placing stones (or molecules) in a disorded state is still a disordered, and thus high entropy, state.

      One useful way to think of the entropy of a system is in terms of information. The amount of information needed to describe a system represents its entropy (in a real and quantifiable way according to QM and Information Theory). A smooth rock wall requires less information to describe than randomly scattered rocks. A crystalline solid requires less information to describe than a plasma. A .png of random noise requires a lot more information to describe than a .png of a solid color -- as can be seen by how well the two compress.

      It doesn't matter how you create the .png of random noise, the result will still compress badly due to its high entropy. Though in practice humans are bad at generating random numbers so the hand-placed "random" .png will have less entropy than one created from a truly random process. If we assume the result is the same, though, then so will be the entropy.

      --

      The enemies of Democracy are
    27. Re:self-replication is easy... by johanatan · · Score: 1

      Sorry, I did confuse matters a bit. My point was merely that there are, and will always be, people arguing both sides of this. There is considerable evidence for the 'mainstream' view of an infinite universe too (which is why the 'topological lens effect' is so remarkable). Open vs closed and finite vs infinite are really two orthogonal concepts and I shouldn't have conflated them.

      But it is the words 'as far as we know' that are the real issue here. We do not know very far and we likely never will. There are some questions which science simply cannot answer. Of course, we will continue to know more as time passes.

    28. Re:self-replication is easy... by Jane+Q.+Public · · Score: 1

      I see what you are saying. And that is true, as far as it goes.

      However, we do know some things, to within certain limits of accuracy, about the observable universe. And in our observable universe, overall entropy always increases, even though localized areas of "complexity building" can occur.

  6. re: incoming replicators by bobmajdakjr · · Score: 0

    i hope we have enough zpm's to power the shield before the replicators get here.

  7. Artificial? by Hentes · · Score: 5, Insightful

    They took DNA, a natural structure that can replicate, and modified it without breking that property. I wouldn't call it artificial self-replication.

    1. Re:Artificial? by DigiShaman · · Score: 2

      At what point will we have a text based programming language that will compile the results into a DNA sequence? Coding the next plague wouldn’t be such good idea. Because you know, there are assholes in this world that would do just that.

      --
      Life is not for the lazy.
    2. Re:Artificial? by Chris+Burke · · Score: 2

      Fair enough. That's true, but they modified it a lot, creating a structure that as far as we know doesn't exist in nature. It replicates without any of the normal cellular chemistry that makes it happen naturally including enzymes, which separates this from the Polymerase Chain Reaction technique for DNA amplification someone mentioned below. It also allows them to replicate structures other than proteins composed of amino acids defined by the normal base pairs.

      They even fabricated the DNA they used, so it's technically artificial. In a more meaningful sense, maybe it's not completely artificial. Not to the extent of things we might make in the future. Still, I don't think it's complete hyperbole for a headline about a significant step.

      --

      The enemies of Democracy are
    3. Re:Artificial? by Daniel+Dvorkin · · Score: 2

      At what point will we have a text based programming language that will compile the results into a DNA sequence?

      Automated production of short sequences is a well-established technology; Google on "custom oligonucleotide synthesis" and "custom gene synthesis" and you'll get links to a bunch of companies that will be happy to manufacture just about any sequence you want. Assembling an entire genome is harder, but not that much. So the answer to your question is pretty much "we're already there."

      Nobody's built any superplagues base pair by base pair yet, and honestly, I think it's not particularly worth worrying about. If unleashing a killer epidemic were your goal, it would probably be easier to take some common, virulent but not terribly dangerous pathogen (say, a rhinovirus) and screen mutants for morbidity and mortality; or alternately, take one of the great plagues of the past (say, smallpox) and alter it to slip past current vaccines.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    4. Re:Artificial? by julesh · · Score: 2

      Erm... no. They took DNA, a natural structure which is half of a system that can replicate (the other half being a collection of enzymes that can transcribe the DNA to RNA, and a ribosome that can take RNA templates and make enzymes, some of which can produce more DNA or ribosomes) and rearranged it into an entirely new structure that doesn't require the assistance of a ribosome to replicate itself.

    5. Re:Artificial? by Anonymous Coward · · Score: 0

      I wouldn't call it artificial self-replication.

      The key is that its "artificial self-replication". Its like self-replication that requires additional external manual processes. It looks like a cool technology, but i would hardly call it "self-replicating" until it can replicate itself without human intervention. When they get to that point, I want to order some gold "dna". ;-)

  8. Abiogenesis by snowgirl · · Score: 1

    Look, it's a watch that self-assembles!

    --
    WARNING! This girl exceeds the MAXIMUM SAFE standards established by the FDA for BRATTINESS
  9. From a Biological Perspective We're Probably Fine by RobinEggs · · Score: 5, Interesting

    I see the first five responses were about science fiction scenarios in which nanomachines destroyed human life.

    All that's really necessary to prevent the machines from getting out of control, however, is to design them with some chemical dependencies. If it needs gold or it can only incorporate carbon from certain uncommon molecules to grow then it can't get very far. Plus, natural selection will be true in part with any self-replicating thing. If they get out they'll have to struggle for resources just like any other form of life. There isn't any reason to automatically assume they'll be better at it simply because they're artificial.

    There are even scenarios in which it might be nice to design nanomechanical organisms with the express purpose of setting them free; I'd sure like an organism that got along by fixing the carbon in carbon monoxide, the ozone in smog, and the nitrogen in nitrogen dioxide to replicate itself. It could make Los Angeles habitable again, and its reproduction would be limited to the rate at which we produce pollutants.

  10. No big deal by Megahard · · Score: 1

    They're basically doing PCR-like reactions to clone DNA-like polymers. Same as DNA amplification has been done for years.

    --
    I eat only the real part of complex carbohydrates.
    1. Re:No big deal by julesh · · Score: 1

      Except, at least as I read the press release, it appears to be self-catalyzing.

  11. Re:From a Biological Perspective We're Probably Fi by Anonymous Coward · · Score: 0

    Until we scorch the skies and they find a new fuel to power themselves!
    (Moral: Perhaps always a way that we don't think about something happening, happening)

  12. Carter! by scorpivs · · Score: 1

    Does General Hammond know about this?

    --
    There is nothing to FEAR but NOTHING itself; and I fear there is a whole lot of nothing going on. --scorpivs
    1. Re:Carter! by Anonymous Coward · · Score: 0

      probably not, he's dead.

  13. Scrabble? by Anonymous Coward · · Score: 0

    "BTX's seed consists of a sequence of seven tiles -- a seven-letter word."
    Bingo!

  14. Stargate references by bgibby9 · · Score: 1

    Wow, totally didn't see that coming :)

    --
    http://www.gibby.net.au
  15. I for one... by thatkid_2002 · · Score: 1

    Welcome our Replicator overlords.

  16. First application: catalog item 2418-B by ConsistentChaos · · Score: 4, Funny

    The Remote Self-Replicating Robot Explorer Probe. Be afraid.

    1. Re:First application: catalog item 2418-B by Tubal-Cain · · Score: 2

      We'll be fine as long as we don't set replication's priority at 999, we should be fine.

  17. Re:From a Biological Perspective We're Probably Fi by russotto · · Score: 1

    All that's really necessary to prevent the machines from getting out of control, however, is to design them with some chemical dependencies.

    That assumes your machines don't mutate, ala Jurassic Park.

  18. Re:From a Biological Perspective We're Probably Fi by erktrek · · Score: 4, Interesting

    I've also heard that the "grey goo" scenario is a bit overstated given that:

    Organisms have already evolved optimal survival strategies over the millennia and if nanobots were made of organic material they would be "prey" to some of these.
    - and -
    The energy requirements for taking on such a task is unlikely to be satisfied in the current environment (especially if made of non organic materials)

  19. Probably Fine? by lister+king+of+smeg · · Score: 1

    Until the organism gets tired of smog and goes to the ozone layer. or the carbon monoxide eating one mutate to dioxide and the plants starve then when all suffocate. "but it would be limited by the amounts of pollutants we create"? no it would go after that small but very necessary amount needed. humans are notorious for screwing up there own environment because it seemed like a good idea at the time.

    --
    ---Saying gnome 3 is better than windows 8 not so much a compliment as it is damning with light praise.
  20. Re:From a Biological Perspective We're Probably Fi by geekmux · · Score: 1

    ...Plus, natural selection will be true in part with any self-replicating thing. If they get out they'll have to struggle for resources just like any other form of life. There isn't any reason to automatically assume they'll be better at it simply because they're artificial.

    You're absolutely right, except you're not taking into account the very mechanism that has allowed almost all current species to survive over the eons; mutation. And unless that is kept in check, then any new self-replicating "organism" will likely follow those same evolutionary lines. Chaos theorists will have a field day with this.

    Personally, I'm a little more concerned at whatever targeted resource is identified to "feed" these...our planet isn't exactly thriving these days with options...perhaps we'll be smart about it and "feed" it human waste. We seem to be damn good at making a shitload of that.

  21. WTF? DNA does NOT self-replicate. by Anonymous Coward · · Score: 0

    DNA does NOT self-replicate, it's just a polymer.

              It is (relatively) easy to use it as a template to make copies using PCR, and of course a variety of enzymes use it as a template to make copies. But it doesn't just "copy itself", no.

  22. Benderama by surement · · Score: 1

    Professor Farnsworth: "Bad news, everyone! Look at this infinite series representing the mass of successive generations of Benders. It's nonconvergent!"

  23. stock up on bullets by Joe_Dragon · · Score: 2

    stock up on bullets

  24. How soon before by flyonthewall · · Score: 2

    Moya?

    Self replication of artifices (self repairs..) is what is going to be needed to long term voyages.

    --
    "The avalanche has already started. It's too late for the pebbles to vote." - Kosh
  25. Self replication by Anonymous Coward · · Score: 0

    Self replication is masturbation. Now self destruction...

  26. It's not blurry at all. WTF? by Anonymous Coward · · Score: 0

    'Self-replication' has a very specific definition, including having a coded representation. I forget the list of very specific properties you need to be considered a 'replicator' but it's more than just 'an ongoing chemical or physical reaction'. Neither of the things you mentioned have all of the properties sufficient to be considered 'self-replication'

  27. Grey goo or something else? by Yvan256 · · Score: 1

    Alright, grey goo has the first comment, so how about evolution?

  28. great bachelordoom... by ThorGod · · Score: 2

    Just when I thought I couldn't get any lower as a bachelor...machines go and gain the ability to replicate - I can't even do that!

    --
    PS: I don't reply to ACs.
    1. Re:great bachelordoom... by BJ_Covert_Action · · Score: 1

      Donate to sperm banks often. You may not know your offspring, but chances are you will have some.

  29. Re:It's not blurry at all. WTF? by znerk · · Score: 1

    'Self-replication' has a very specific definition, including having a coded representation. I forget the list of very specific properties you need to be considered a 'replicator' but it's more than just 'an ongoing chemical or physical reaction'. Neither of the things you mentioned have all of the properties sufficient to be considered 'self-replication'

    By that argument, is human reproduction "replication"?

    --
    This work is licensed under a Creative Commons Attribution 3.0 Unported License.
  30. Skeptical by Anonymous Coward · · Score: 0

    I'm very skeptical which this whole self replicating artificial DNA

  31. Micheal Behe is sobbing by goombah99 · · Score: 1

    Poor poor micheal Behe. Irrefutably refuted by construction of a mouse trap from itself.

    --
    Some drink at the fountain of knowledge. Others just gargle.
  32. Re:replicators by Culture20 · · Score: 1

    This did not work out well on SG-1

    They're rather benign on DS-9, except when they malfunction and your "tea, earl grey, hot" is replaced with its gotee'd evil twin.

  33. A brief rant on scientists and terminology by subreality · · Score: 1

    Scientists have developed...

    OK, I have something that's been bugging me for a while.

    Scientists discover things. Engineers develop things. Frequently someone can do both, but they're two different processes.

    There's this terrible societal misconception that "scientist" means someone who works with technology. It leads to the mistrust of scientists because they're perceived as some ivory tower loonies who're lording technology over the populace.

    Scientists are people who apply the scientific method to acquire knowledge. I don't expect CNN to get it, but please, let's at least try to get it right here.

    1. Re:A brief rant on scientists and terminology by artor3 · · Score: 1

      I think you're thinking of theorists. Experimental scientists run experiments. Those experiments involve developing prototypes and running tests on them. Engineers also develop prototypes and run tests. The difference is the goal: scientists do it to learn, engineers do it to create a product to sell.

    2. Re:A brief rant on scientists and terminology by Anonymous Coward · · Score: 0

      Scientists discovered how to make artificial structures that can self replicate...

    3. Re:A brief rant on scientists and terminology by kwikrick · · Score: 1

      A scientists ask the question: can it be done? and then starts tinkering. If it works, the answer is yes. If he doesn't succeed, the question is still open.
      Ask an engineer the same question, he will either say yes, and then build it, or say no, and move on. Or in the worst case, the engineer says yes, and then fails.
      The scientist of course can never fail - only get negative results. Cheap trick.

      --
      assignment != equality != identity
    4. Re:A brief rant on scientists and terminology by Chris+Burke · · Score: 2

      You're drawing a line where none exists, and in the wrong place to boot.

      Engineers develop useful, practical things. Things that serve a particular need, that can be made economically, etc.

      Scientists develop things, too, but they aren't as often concerned with the direct utility or practicality of what they develop. For instance what these scientists developed is an ingenious proof-of-concept that could eventually be developed into a practical procedure for replicating materials, possibly by a chemical engineer.

      However scientists also frequently develop practical, useful things. The PCR process you have seen mentioned in this thread is incredibly useful and practical, and was developed by a chemist.

      Sometimes the line gets really blurry, like in the development of a new technology for silicon IC fabrication. The material science and the material engineering are closely coupled and it's hard to say specifically which is which in a given case, outside of edge cases.

      --

      The enemies of Democracy are
  34. Sound suspiciously like PCR to anyone else? by BillX · · Score: 1

    From the article:

    DNA replication process involves complementary matches between bases -- adenine (A) pairs with thymine (T) and guanine (G) pairs with cytosine (C) -- to form its familiar double helix. By contrast, the NYU researchers developed an artificial tile or motif, called BTX (bent triple helix molecules containing three DNA double helices)

    In order to achieve self-replication of the BTX tile arrays, a seed word is needed to catalyze multiple generations of identical arrays. BTX's seed consists of a sequence of seven tiles -- a seven-letter word. To bring about the self-replication process, the seed is placed in a chemical solution, where it assembles complementary tiles to form a "daughter BTX array" -- a complementary word. The daughter array is then separated from the seed by heating the solution to ~ 40 oC. The process is then repeated.

    "While our replication method requires multiple chemical and thermal processing cycles,

    I think Megahard above has it right, it sounds like they reproduced the well-known PCR chemistry on some fake DNA. I will admit having fake DNA itself is mildly interesting, but not exactly novel (folks like DIYBio do this at the hobbyist level - or at least buy made-to-order DNA sequences from labs - and I've seen hackerspace Bio'ers doing PCR literally in a kitchen sink). "Self-replicating" a DNA sequence via a PCR-like reaction is kind of like gluing a row of magnets to a board, dipping it into a bucket of more magnets and being surprised to find that your original magnets now have an exact copy of the N/S pole arrangement stuck to them. Self-replicating structure? Technically maybe, but not exactly the gray-goo scenario it's cracked up to be.)

    --
    Caveat Emptor is not a business model.
    1. Re:Sound suspiciously like PCR to anyone else? by julesh · · Score: 2

      Also FTFA:

      no biological components, particularly enzymes, are used in its execution

      So no, not PCR or PCR-like, as such processes require enzymes.

  35. Re:From a Biological Perspective We're Probably Fi by cstacy · · Score: 1

    Make sure the machines have a lysine dependency (but cannot manufacture it themselves).
    Also, just make them all female.
    That should do it!

  36. Re:From a Biological Perspective We're Probably Fi by Kjella · · Score: 1

    Until it mutates into something that's not so restricted, and if it then has huge food sources it can devour alone it'll spread like wildfire. On a much less sci-fi note, a true global pandemic is still one of those really scary scenarios despite all the hype. If it first spirals out of control and you have people fleeing everywhere breaking quarantine it could get really, really nasty.

    --
    Live today, because you never know what tomorrow brings
  37. Re:From a Biological Perspective We're Probably Fi by Alef · · Score: 1

    You mean they will struggle like rabbits and foxes did in Australia when Europeans brought them there? Introducing new species into an existing ecosystem quite commonly screw things up, and then we are still talking about life forms that are rather similar to what is already there. I imagine that some sort of artificial life form, that the existing species have no "evolutionary experience" defending themselves against, could do a lot more harm.

  38. I claim prior art! by Anonymous Coward · · Score: 0

    Another artificial structure that can self-replicate:

    while( fork() );

  39. Re:From a Biological Perspective We're Probably Fi by Anonymous Coward · · Score: 0

    That will just make them want to fight for the rare material.

  40. Past tense by Anonymous Coward · · Score: 0

    Is Slashdot finally admitting that their stories are hopelessly out of date by writing their headlines in the past tense?

  41. Sephirot by Anonymous Coward · · Score: 0

    The image reminds me of the Kabbalah Sephirot:
    http://en.wikipedia.org/wiki/Sephirot

  42. This is not a big deal by NichardRixon · · Score: 1

    Run-away replication has already happened over forty years ago when the Starship Enterprise was overrun with tribbles. All it takes is a great intellect like that of Capt. James T. Kirk to deal with the problem.

    What's that? Star Trek was a work of fiction?

    That's different.

    Never mind.

    ----NR

  43. Should be modded up. by Anonymous Coward · · Score: 0

    Above post is relevant, and the opening clause is funny. This article != grey goo, but it does = another advancement in our genomic/biomechanical technology.

  44. Re:From a Biological Perspective We're Probably Fi by Anonymous Coward · · Score: 0

    if nanobots were made of organic material

    Malicious entities will make sure that is not the case. I know I'd see fit to eliminate that aspect of any weapon.

  45. Re:From a Biological Perspective We're Probably Fi by Intrepid+imaginaut · · Score: 2

    Remember though, there is no animal on earth that is superior to a simple rifle. We're quite capable of building a bionuke, intelligence goes to places evolution never would or perhaps could.

  46. Re:From a Biological Perspective We're Probably Fi by YouDieAtTheEnd · · Score: 0
    FTFY:

    That assumes your machines don't mutate, ala Jurassic Park.

    There we go, now it's a real /. comment.

    Also: Did you just cite Jurassic Park?

  47. Re:From a Biological Perspective We're Probably Fi by benhattman · · Score: 1

    Nonsense. Evolution excels at finding local optima, but there is nothing in evolution that suggests it will find global optima. With regards to energy requirements, consider for a moment that plants are green and not black. That means, they are not converting the green spectrum into energy at all. Which means, that an artificial plant, which absorbed all natural solar produced light spectrums (sp) would have more energy to work with than a natural plant does, which means it could definitely out compete the natural specimen.

    Grey Goo may be an exaggerated scenario, but I find it far more compelling of an argument than the supervirus or nuclear winter types of fears that prevail in the mainstream.

  48. Re:From a Biological Perspective We're Probably Fi by painandgreed · · Score: 1

    All that's really necessary to prevent the machines from getting out of control, however, is to design them with some chemical dependencies.

    It's going to be so hard to build machines without some chemical dependencies, that having them get out of control really won't be a problem. Nature has been trying to do that for millions of years and molds and bacteria do quite well but all exist pretty much only in a specific environment for whatever type they are. I doubt if we will ever be able to build a robust self replicating machine that will do any better, and I'd bet that when we do build one, it will look a lot like what nature has developed already.

  49. Re:From a Biological Perspective We're Probably Fi by YouDieAtTheEnd · · Score: 0

    Ok, put a rifle and a panther in a cage together and see who wins. Better yet, put a human sans tools and a panther in the wilderness and see who wins. Spoilers: the panther wins. The point is that it takes a social support network of dozens if not hundreds of people and their accumulated knowledge to produce one rifle and only one large cat to rip your face off. Without our society and thousands of years of accumulated knowledge we're just another bag of meat.

    Once we start mucking around on nature's home turf, we're seriously outmatched. Consider that we're just learning to put bits together that can reproduce their own instructions, never mind an entire cell. Prokaryotic life has been at it for 3.5 billion years and has produced organisms that will happily munch on both organic and inorganic compounds. The variety of species or OTU (operation taxonomic units) of prokaryotes is so astronomically large that many microbiologists would conclude that given our current methodologies for culturing them and sequencing their genomes it is not currently possible to say how many in total they may be . Some estimates of the number of OTUs in sampled soil have ranged anywhere from 6,000 to 10,000 or up to 500,000 [1]. The sheer mass of prokaryotic life has been estimated to be as high as 5.46 x 10^14 Kg [2].

    In short, whatever we think we might be capable of doing in the near future chances are that life has already accomplished it millions of years ago. So if you're looking for bionukes you don't have to go any further than your back garden.

  50. Make them as powerful you can... by Anonymous Coward · · Score: 0

    The original article states....

    "While our replication method requires multiple chemical and thermal processing cycles, we have demonstrated that it is possible to replicate not just molecules like cellular DNA or RNA, but discrete structures that could in principle assume many different shapes, have many different functional features, and be associated with many different types of chemical species," added Nadrian Seeman, a professor in NYU's Department of Chemistry and a co-author of the study.

    Yes... make them as powerful you can for that one PhD thesis or one grant you want to show off oh-so-much... and then wait and watch until some dumbass makes that wrong move at the right time... Hey Oppenheimer never wanted to kill...

  51. And yes... Make them as powerful you can by TwinkNinja · · Score: 1

    The original article states.... "While our replication method requires multiple chemical and thermal processing cycles, we have demonstrated that it is possible to replicate not just molecules like cellular DNA or RNA, but discrete structures that could in principle assume many different shapes, have many different functional features, and be associated with many different types of chemical species," added Nadrian Seeman, a professor in NYU's Department of Chemistry and a co-author of the study. Yes... make them as powerful you can for that one PhD thesis or one grant you want to show off oh-so-much... and then wait and watch until some dumbass makes that wrong move at the right time... Hey Oppenheimer never wanted to kill...

  52. Re:From a Biological Perspective We're Probably Fi by Anonymous Coward · · Score: 0

    Ok, now put a panther in a cage with an automated defense turret that targets body heat and see who wins.

  53. I would like to be the first to welcome our.... by Anonymous Coward · · Score: 0

    I would like to be the first to welcome our self replicating overlords!

    And what happens when they (meaning 'well' intentioned corporations) put the self replicating matter at the control of IBM's new 'cognitive' computing systems?

    I see many bad things happening in the latter half of this century.

  54. Re:From a Biological Perspective We're Probably Fi by BJ_Covert_Action · · Score: 1

    That actually depends on the rifle and the animal. I'm pretty sure a simple .32 wouldn't bring down a full grown bull elephant... or, for that matter, even an octopus. And I'd still be interested in seeing the rifle that can take out a large ant colony.

  55. The Diamond Age by 21mhz · · Score: 1

    Oh no, they have created the Seed.
    Quick, call Protocol Enforcement.

    --
    My exception safety is -fno-exceptions.