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Aspirin Helps Prevent Cancer, New Studies Show

kkleiner writes "For years, research has shown that aspirin is beneficial in preventing heart attacks. Now new studies support its ability to prevent cancer as well. The studies, involving tens of thousands of participants over many decades, show reductions of cancer incidence (both short- and long-term) and mortality rate as well as a decrease in metastatic cancer. It still is not known exactly how aspirin and cancer are connected, but those between the ages of 45-50 will now likely consider taking low-dose aspirin daily for the remainder of their lives."

132 comments

  1. Goddamn Futurism "Reporting" by eldavojohn · · Score: 5, Informative

    100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

    Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

    For all the money spent on studies of aspirin, perhaps all the evidence anyone needs of its health benefits is the life of Walter Breuning, who lived to be 114 years old and aspirin was the only medication he ever took.

    Oh, you just need a sample size of one? No need for that expensive tens of thousands double blind study, huh? And all he ever took was aspirin? We should refuse vaccines? And what the hell do you mean by "for all that money spent"? I find it odd that all three of the abstracts linked to in the article end with:

    Funding
    None.

    Wait a second ... *checks URL*

    singularityhub.com

    Oh son of a bitch, it's more misinformation and half truths from Ray Kurzweil's disciples. Now I have to guess which is which.

    --
    My work here is dung.
    1. Re:Goddamn Futurism "Reporting" by Jeremiah+Cornelius · · Score: 5, Funny

      "perhaps all the evidence anyone needs of its health benefits..."

      Well, my grandmother relied exclusively on anecdotal evidence, and SHE lived to be 103!

      --
      "Flyin' in just a sweet place,
      Never been known to fail..."
    2. Re:Goddamn Futurism "Reporting" by mcgrew · · Score: 4, Informative

      Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

      Neither, it was on TV news last night. It's a peer-reviewed study with unexpected results. Here are a couple of more reputable sources than the stupid FA that I didn't bother reading:

      Can aspirin really reduce the risk of cancer?
      Studies Link Daily Doses of Aspirin to Reduced Risk of Cancer

      Unfortunately, many folks seem to pick the least reputable rag they can find as a link for their submissions, often their own blogs.

      Aspirin isn't for everyone. Kids under 16 shouldn't take it, especially if they have the flu, and if you have stomach or digestive problems, hemophilia, or a few other conditions aspirin can be dangerous.

      I wonder if Naproxin Sodium prevents cancer? I stopped taking aspirin when the patent on Alieve went away.

    3. Re:Goddamn Futurism "Reporting" by WrongSizeGlass · · Score: 1

      "perhaps all the evidence anyone needs of its health benefits..."

      Well, my grandmother relied exclusively on anecdotal evidence, and SHE lived to be 103!

      Was she related to Jiminy Cricket?

    4. Re:Goddamn Futurism "Reporting" by hrvatska · · Score: 5, Informative

      100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

      Hmmm, that's odd, this "news" story reads like one of those ads trying to sell me something. Is this ancient Chinese secret or midwest housewife research?

      Maybe you like it straight from 'The Lancet': Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials, Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials, and Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials.

      The NY Times also reported on these studies. Some of the findings of these studies found were that after five years the risk of dying of cancer was reduced by 37 percent among those taking daily aspirin, that over six and a half years, on average, daily aspirin use reduced the risk of metastatic cancer by 36 percent and the risk of adenocarcinomas by 46 percent, daily aspirin use reduced the risk of progressing to metastatic disease in patients with colorectal cancer.

      It was found that the risk of bleeding in aspirin users diminished over time, and that the risk of death from brain bleeds was actually lower in the aspirin users than in the comparison group.

    5. Re:Goddamn Futurism "Reporting" by ColdWetDog · · Score: 4, Insightful

      This has been going on for years - low dose aspirin either helps or it doesn't help.

      Here's a couple of take home messages - the canonical study would be to see if low dose aspirin helps you live longer (live 'better' would be a much more useful metric, but pretty much impossible to do). IIRC, the studies that looked at that did not find any benefit from aspirin.

      Second - all of these aspirin / cancer link studies have been pulled from aspirin and heart disease studies - these were secondary effects and the studies neither designed nor powered to ask whether or not aspirin was useful for cancer prevention. When you do this, you are pretty much at the mercy of people who purport to understand statistics much better than the vast majority of folks. Lies, damned lies and .... statistics.

      And finally, when you see reports that a certain drug / treatment / lifestyle does or does not work over a number of various and sundry studies, it means that the value of the treatment / drug / lifestyle isn't all that much. In other words, the effect is just barely over the noise floor.

      Don't worry about it, you're gonna die anyway.

      --
      Faster! Faster! Faster would be better!
    6. Re:Goddamn Futurism "Reporting" by Anonymous Coward · · Score: 1

      OK. That right there is why "Funny" deserves karma.

    7. Re:Goddamn Futurism "Reporting" by Mister+Whirly · · Score: 4, Informative

      Naproxen Sodium is not to be taken daily for a long term or it can cause kidney problems. I know someone who found this out the hard way after taking it daily for over a year. Maybe she should have read the warning about consulting a doctor about long term use and the directions to stop taking it after two weeks.

      --
      "But this one goes to 11!"
    8. Re:Goddamn Futurism "Reporting" by oldhack · · Score: 1

      Death prevents cancer. Try that, but it's only a suggestion, not a recommendation.

      --
      Fuck systemd. Fuck Redhat. Fuck Soylent, too. Wait, scratch the last one.
    9. Re:Goddamn Futurism "Reporting" by Anonymous Coward · · Score: 5, Funny

      Don't worry about it, you're gonna die anyway.

      The evidence speaks against it. In all the time I lived, I've died exactly zero times. Therefore the experiment "will I die this second" has a huge about of evidence against (typical science experiments are data-starved in comparison!), the number of repetitions being larger than a billion, all with the same result: "No". Therefore I conclude that I'll never die. :-)

    10. Re:Goddamn Futurism "Reporting" by mcgrew · · Score: 2

      Here's a couple of take home messages - the canonical study would be to see if low dose aspirin helps you live longer (live 'better' would be a much more useful metric, but pretty much impossible to do).

      No one with arthritis needs a scientific study to know that aspirin does indeed help the quality of life. All analgesics do, that is if they work on you (Tylenol has no effect on me at all, except perhaps liver damage). Likewise, you don't need a scientific study to know that if you go outside in the rain you'll get wet, and if you stick your hand in a flame it will burn.

      As to statistics, it's just the odds and isn't predictable for any given person. For example, it's proven that cigarettes cause cancer and lead to a short life, but my great uncle started smoking at age 12 and quit at age 82, and lived another 12 years. But just because he lived a very long life despite his smoking doesn't mean smoking's not dangerous. Likewise, just because fewer people who take aspirin daily get cancer than those that don't doesn't mean that if you take aspirin you don't need to worry about cancer.

    11. Re:Goddamn Futurism "Reporting" by Anonymous Coward · · Score: 0
      Second - all of these aspirin / cancer link studies have been pulled from aspirin and heart disease studies - these were secondary effects and the studies neither designed nor powered to ask whether or not aspirin was useful for cancer prevention.

      It is not important that these are secondary effects, there is nothing wrong with the secondary use of data. It is perfectly legitimate to use a heart attack study and look for secondary effects like cancer, weight gain, etc.. as long as the events are captured and controlled for. Why wouldn't it be?

      You mention "power" which I assume you mean statistical power which has nothing to do with evaluating these studies. Power calculations are used to determine if you should bother to do the study in the first place (what are you chances of detecting an effect). They detected an effect so who cares about the power calculation.

      And finally, when you see reports that a certain drug / treatment / lifestyle does or does not work over a number of various and sundry studies, it means that the value of the treatment / drug / lifestyle isn't all that much. In other words, the effect is just barely over the noise floor.

      No, it doesn't mean this at all. It is actually better to have more data and more studies to draw on. This effect is all the more striking because the effect is actually quite large.

    12. Re:Goddamn Futurism "Reporting" by mcgrew · · Score: 1

      Naproxen Sodium is not to be taken daily for a long term or it can cause kidney problems.

      Thank you, I didn't know that. Glad I don't hurt every day.

    13. Re:Goddamn Futurism "Reporting" by ColdWetDog · · Score: 2

      No, my point is that using aspirin to keep you from getting cancer does need a suitably powered high quality study (as opposed to using data generated from another study) because it's not clear if it helps.

      Taking aspirin for arthritis is pretty easy - you take it, you're better or you're not in a couple of days on the outside. You can tell if it's going to trash your GI tract in a couple of weeks. So with n=1, you're study is pretty good. Put a couple of thousand people in the study and you can find some less common side effects (always good to know) and get a better picture of how well the drug works.

      Taking aspirin for cardiovascular or cancer prevention is a whole different story. Your chances of getting colorectal cancer in the US (without a strong family history) is about 1 in 10000 (number from memory, it may well be wrong). Your risk for cardiovascular disease is a bit more complex but pretty well studied. But even if you're a 60 year old hypertensive smoker it's perhaps 1 in 50. So then you need reasonably powered studies to tease out the benefits and risks.

      Current studies seem to indicate that for people at low risk of cardiovascular disease (ie, not diabetic, no previous heart attack or similar) don't benefit from daily low dose aspirin. This runs counter to older studies - but the newer studies are supposedly cleaner and better powered. This is an all to common finding in drug or treatment studies - early studies seem to yield better results that later ones. (cf, hormone replacement in menopausal women, bisphophonate treatment for osteoporosis, HDL cholesterol raising drugs, LDL cholesterol lowering drugs, etc.).

      So other studies will be done and the balance may shift a bit over time - or we may discover a previously unknown variable that needs to be accounted for and the cycle will begin anew.

      But a reasonable approach to something in medicine where studies are all over the map is that it doesn't make a whole lot of difference in a large population. There may be subpopulations where the treatment is really effective, but until you tease that out, you're just guessing.

      In the case of aspirin, assuming that it doesn't give you ulcers and assuming that you don't need urgent trauma surgery, the risks and costs are pretty low. For other drugs, perhaps not so much.

      --
      Faster! Faster! Faster would be better!
    14. Re:Goddamn Futurism "Reporting" by pepty · · Score: 1

      It is not important that these are secondary effects, there is nothing wrong with the secondary use of data. It is perfectly legitimate to use a heart attack study and look for secondary effects like cancer, weight gain, etc.. as long as the events are captured and controlled for. Why wouldn't it be?

      obligatory XKCD: You can certainly use data on secondary effects, but it's a lot more dicey to draw conclusions from it.

    15. Re:Goddamn Futurism "Reporting" by swalve · · Score: 1

      Probably because the anti-inflammatory effects of aspirin prevented the conditions that caused brain bleeds in the first place.

    16. Re:Goddamn Futurism "Reporting" by Anonymous Coward · · Score: 0

      Oh, please. Like a 3-digit UID user needs karma. It's not like it's hard to get even for a new user.

    17. Re:Goddamn Futurism "Reporting" by jones_supa · · Score: 1

      Exactly!

      And the number of people that are alive today on earth is higher than the number of people that have ever lived here, further proving your conclusions.

    18. Re:Goddamn Futurism "Reporting" by mcgrew · · Score: 1

      using aspirin to keep you from getting cancer does need a suitably powered high quality study

      I agree, it does need more study.

      You can tell if it's going to trash your GI tract in a couple of weeks.

      Not so. I had a friend a few years ago who got a hole in her intestine from daily high doses of Naproxin, which has the same effect (good and bad) as aspirin. Ironically, she'd been taking the Naproxin for stomach pain.

  2. Contraceptive. by wcrowe · · Score: 5, Funny

    It's also a good contraceptive, according to Rush Limbaugh.

    --
    Proverbs 21:19
    1. Re:Contraceptive. by Jeremiah+Cornelius · · Score: 5, Funny

      I'd like to establish a control set for Rush's experiment. I beleive that it is actually his "personality" which is the mechanism preventing fertilization.

      --
      "Flyin' in just a sweet place,
      Never been known to fail..."
    2. Re:Contraceptive. by Anonymous Coward · · Score: 3, Informative

      Amusing barb, but completely wrong. Foster Friess was the person who said that.

    3. Re:Contraceptive. by OakDragon · · Score: 1

      And, if used as instructed.

    4. Re:Contraceptive. by sorak · · Score: 1, Funny

      AC is right. Foster Friess said it's a good contraceptive. Rush said that anyone who uses contraceptive is a slut. So the summary must be suggesting that anyone over the age of 45 become a slut, for health purposes.

    5. Re:Contraceptive. by ChrisMaple · · Score: 2

      Nice try, liar. What Rush said was (approximately) that anyone spending $1000 a year on contraceptives was a slut. Sounds like a pretty good estimate to me.

      --
      Contribute to civilization: ari.aynrand.org/donate
    6. Re:Contraceptive. by Anonymous Coward · · Score: 0

      Nice try, liar. What Rush said was (approximately) that anyone spending $1000 a year on contraceptives was a slut. Sounds like a pretty good estimate to me.

      That pretty much sums it up.

      Why should I (a taxpayer) be paying for her contraceptives so that she can have all that sex with men that are not me.

    7. Re:Contraceptive. by 93+Escort+Wagon · · Score: 1

      It's also a good contraceptive, according to Rush Limbaugh.

      Especially if she holds it between her knees.

      --
      #DeleteChrome
    8. Re:Contraceptive. by drinkypoo · · Score: 1

      Nice try, liar. What Rush said was (approximately) that anyone spending $1000 a year on contraceptives was a slut. Sounds like a pretty good estimate to me.

      I think anyone making generalizations about other people's sex habits is an asshole. Sounds like a pretty clear proper use of the word to me.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    9. Re:Contraceptive. by sorak · · Score: 1

      Actually, she was testifying about someone who needed contraceptives for non-contraceptive purposes. Also, you do realize that the amount of contraceptive a woman needs is in no way related to how much sex she has, right?

  3. But destroys your liver by cpu6502 · · Score: 3, Interesting

    I'd rather avoid aspirin and other NSAIDs (like tylenol/acetaminophen).

    --
    My AC stalker: " I personally agree with your posts most of the time, but that won't keep me from modding you troll"
    1. Re:But destroys your liver by XxtraLarGe · · Score: 5, Informative

      I'd rather avoid aspirin and other NSAIDs (like tylenol/acetaminophen).

      But then again...

      A 2009 article published by the Journal of Clinical Investigation suggested that aspirin might prevent liver damage.

      Source: http://en.wikipedia.org/wiki/Aspirin#Experimental

      --
      Taking guns away from the 99% gives the 1% 100% of the power.
    2. Re:But destroys your liver by Anonymous Coward · · Score: 0

      ... but acetaminophen is a liver toxin...

    3. Re:But destroys your liver by Daniel+Dvorkin · · Score: 5, Informative

      I'd rather avoid aspirin and other NSAIDs (like tylenol/acetaminophen).

      Acetaminophen's not an NSAID, since it has hardly any anti-inflammatory effect at all. Still something that should IMO be avoided -- aspirin's actually a lot healthier and safer for most people -- but it's important to know what class of drugs you're actually dealing with.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    4. Re:But destroys your liver by fahrbot-bot · · Score: 4, Informative

      Acetaminophen's not an NSAID,

      Furthermore, as far as I know, it's only Acetaminophen (Tylenol) that has been shown to potentially cause liver failure using regular 2 x 325mg doses, and only when taken with alcohol over a period of a few days. The articles I've read about liver failure from NSAIDs have been from using high(er) doses of Ibuprofen or Naproxen - both of which are stronger than Aspirin - continuously over a long period of time, like for arthritis pain control. But, IANAMD.

      --
      It must have been something you assimilated. . . .
    5. Re:But destroys your liver by Hatta · · Score: 4, Informative

      Aspirin is not harmless either. About 10,000 Americans a year suffer gastric bleeding due to aspirin. There is absolutely a tradeoff to be made here. Don't go on aspirin therapy without fully considering the risks.

      --
      Give me Classic Slashdot or give me death!
    6. Re:But destroys your liver by Cro+Magnon · · Score: 1

      Agreed! Maybe the reason aspirin users had less cancer is because they died from ulcers first.

      --
      Slow down, cowboy! It has been 4 hours since you last posted. You must wait another few hours.
    7. Re:But destroys your liver by mcgrew · · Score: 3, Informative

      First, tylenol isn't an NSAID. Second, wikipedia says that aspirin only affects the liver of 20% of children who take it in high doses. If aspirin destroyed your liver mine would have been gone in 1971 when I took huge doses daily for arthritis; it was the only effective drug (for me) back then. I'm amazed I never got a stomach ulcer.

      Acetaminophen, otoh, has a bad effect on the liver even in lower doses, and in everyone regardless of age.

      There are far better reasons to avoid aspirin; it isn't for everyone. But liver damage from low doses isn't one of the risks.

    8. Re:But destroys your liver by ChrisMaple · · Score: 3, Informative

      The aspirin dose used in these tests is 1/4 of a standard tablet a day. That's 1/48th ( 2 per cent ) of the dose used for persistent pain relief. Some people are sensitive to even that small dose, but not many. For most people, there's no tradeoff.

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    9. Re:But destroys your liver by jones_supa · · Score: 1

      Yes, it's almost scary. More info in the Wikipedia article Paracetamol toxicity (paracetamol = acetaminophen):

      Mainly causing liver injury, paracetamol toxicity is one of the most common causes of poisoning worldwide. In the United States and the United Kingdom it is the most common cause of acute liver failure.

  4. Theory of anti-cancer mechanism by Anonymous Coward · · Score: 0

    Patients die of GI bleeding before the cancer can get them.

    1. Re:Theory of anti-cancer mechanism by Anonymous Coward · · Score: 0

      In other news: Suicide Helps Prevent Cancer!

    2. Re:Theory of anti-cancer mechanism by Tmann72 · · Score: 2

      That's why they say to take low doses. I recently had a TIA and the doctor told me I should take a dose of baby aspirin daily (81mg). 81mg isn't enough to cause GI bleeding.

  5. uhhhh....no by Anonymous Coward · · Score: 0

    Yeah....last I heard there was actually 0 factual evidence that aspirin even does anything to help prevent heart attacks by taking it daily. I hear that if you have nothing better, taking it "during" a heart event can help....but the whole daily thing is pretty much unproven to any meritable degree.

    1. Re:uhhhh....no by berashith · · Score: 1

      I think the idea is that if you have aspirin in your system during the attack, then you have better odds. If you take it every day, then you have a chance of having aspirin in you system at the time of the heart attack.

    2. Re:uhhhh....no by PRMan · · Score: 1

      Read the article. They have a very plausible reason why aspirin could help with various forms of cancer.

      --
      Peter predicted that you would "deliberately forget" creation 2000 years ago...
    3. Re:uhhhh....no by compro01 · · Score: 2

      The idea of a daily aspirin regimen is that ASA is a mild anti-coagulant, so you won't have sizable clots forming and finding a section of narrowed/hardened artery to block.

      --
      upon the advice of my lawyer, i have no sig at this time
  6. It's not misinformation by pigwiggle · · Score: 5, Informative

    it's actual, real life, scientific research - published in a well read and respected peer reviewed medical journal. But if it's just the messenger that has you all wee weed up, try PBS
    http://www.pbs.org/newshour/bb/health/jan-june12/aspirin_03-21.html

    --
    46 & 2
    1. Re:It's not misinformation by Anonymous Coward · · Score: 0

      wee weed

      Did Palin actually establish a meme I'm expected to tolerate around here?

    2. Re:It's not misinformation by oldhack · · Score: 1

      it's actual, real life, scientific research - published in a well read and respected peer reviewed medical journal.

      And that tells volumes on what today's "well read and respected peer reviewed" medical research amount to these days.

      Of course, they'd blame the reporters, but you know the researchers are in on it because they know more publicity means more funding.

      --
      Fuck systemd. Fuck Redhat. Fuck Soylent, too. Wait, scratch the last one.
    3. Re:It's not misinformation by dbet · · Score: 3, Interesting

      It's real science, but it's bad science reporting.

      First, the difference reported was small. The largest decrease in risk, in women, was 25%. 3.1 vs 3.9 deaths per 1000 people. That's what 3 years of aspirin is purchasing for you (for men the difference was smaller). This is what people fail to look at whenever it comes to incidence of disease. When something is increased by x% more than y, it's really important what y is.

      Second, are there any negative effects of taking aspirin daily? Maybe? This paper doesn't address this, because it doesn't look for it. So telling the public that daily aspirin is a good idea is short-sighted. It's also medical advice that a single research paper can't really provide.

      Third, I searched around and could only find summaries, so I'm questioning their methodology. But so far I can't find the info I'm looking for. What I'm interested in is the subject selection. Who these people were and where they come from is important. If for example the average age of participants was 70, the advice hold less weight for people who are 20. If all the participants were from the UK, maybe there are factors specific to people from the UK that would invalidate this finding if it were preformed in China.

      I guess what I'm saying is, this one paper shouldn't change anyone's behavior or be considered medical advice.

    4. Re:It's not misinformation by Tokolosh · · Score: 4, Informative
      --
      Prove anything by multiplying Huge Number times Tiny Number
    5. Re:It's not misinformation by dgatwood · · Score: 2

      Second, are there any negative effects of taking aspirin daily?

      You mean besides increased risk of hemorrhagic strokes and other internal bleeding?

      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

    6. Re:It's not misinformation by krotkruton · · Score: 1

      I guess what I'm saying is, this one paper shouldn't change anyone's behavior or be considered medical advice.

      Sure, that one article isn't a good reason to change your behavior, but the linked article by the GP is not the same as the studies in the summary. There were three meta-analyses in the article, so it's not just 'one paper' or really even three papers. Maybe you were only referring to the GP's article, but I think the GP's point was to post yet another article in support of the meta-analyses from the summary, which is completely different from saying that you should take that single article as enough evidence to change your habits.

    7. Re:It's not misinformation by rs79 · · Score: 2

      I'd take it a lot more seriously if they'd outlined a nice big cascading set of biochemical events that happened because aspirin was introduced, but they don't and don't have a clue how it works or really if it works at all.

      It seems odd to me because nasis block the cox2 reaction which produces prostoglandins which reduce inflammation which causes cancer. So I'd expect any antagonist of this reaction to increase, not decrease cancer morbidity.

      --
      Need Mercedes parts ?
  7. Stop listening to observational studies by Anonymous Coward · · Score: 3, Interesting

    Observational studies are almost always behind these news reports. Please ignore them. They don't prove causation. Here's some detailed analysis from the latest "red meat causes x" articles to get an idea why they're so unreliable:

    http://garytaubes.com/2012/03/science-pseudoscience-nutritional-epidemiology-and-meat/
    http://www.marksdailyapple.com/will-eating-red-meat-kill-you
    http://waroninsulin.com/nutrition/is-red-meat-killing-us

    1. Re:Stop listening to observational studies by jcaldwel · · Score: 2
      I thought the exact same thing. I'm usually pretty skeptical of any "wonder drug" claims, so I tried "following the money" to see if it was funded by Bayer or something similar, and I noticed the abstract said:

      Funding: None

      This surely means that this study probably consisted of data mining, and that's about it. That's enough to establish correlation, but correlation != causation.

    2. Re:Stop listening to observational studies by ceoyoyo · · Score: 1

      Yes, because it's perfectly possible that getting cancer in the future causes you not to take Aspirin today.

    3. Re:Stop listening to observational studies by ceoyoyo · · Score: 1

      The patents on ASA expired a long time ago.

    4. Re:Stop listening to observational studies by samazon · · Score: 1

      But red meat IS KILLING US. *cough* I remember the days when I argued with people about the lethality of smoking, and won several (formal) arguments about correlation vs. causation re: lung cancer and smoking (essentially, at the time, there was no scientific proof of causation). I am one who enjoys arguing about things for the sake of proving a point (which is that she who has the best evidence, wins, regardless of common knowledge/social mores) - but this is ridiculous. I'm sick of people telling one another what they should do/be/eat/whatever to maintain a socially acceptable standard of health.

      --
      I have the hiccups.
    5. Re:Stop listening to observational studies by mcgrew · · Score: 1

      It could possibly be that what causes you to take the aspirin (pain, fever, heart disease) prevents cancer, and taking aspirin is just a side effect of the cause of the reduced cancer risk, and not the cause itself.

      However, it's probably likely that it's the aspirin itself. But you would need more study to be sure.

    6. Re:Stop listening to observational studies by ceoyoyo · · Score: 1

      Yes, it could be a third factor, but as you say, probably not. Either way, it's something interesting. Observational studies are useful because they let us look at things that are very difficult or impossible to do any other way and they give us interesting correlations to examine further, and frequently very probable causal relationships.

    7. Re:Stop listening to observational studies by Rich0 · · Score: 1

      Here is my problem with these kinds of studies. Did they enroll thousands of people for many years specifically to test whether aspirin prevents cancer? I doubt it. They probably were testing for prevention of heart disease and found additionally that it reduces cancer.

      So, what's wrong with that, you ask. Xkcd as usual sums it up.

      Well, how likely is it that the conclusion is right? The scientists will no doubt show that it is 99% likely that they are right based on confidence limits and all that. However, that doesn't account for how many hypothesis were tested. If you give me a big data set with lots of individual maladies within it, I can show a 99% confidence relationship to SOMETHING in that list for sure.

      The only way I trust a clinical trial is if the endpoint of the trial was declared BEFORE the trial was started, and then THAT endpoint was reached. Repeat this whole trial again looking specifically for cancer and I'll believe the results, even if EVERY aspect of the trial is conducted in the same way.

      This sort of argument might seem strange to somebody not versed in statistics, but hypothesis is mining is a big problem.

  8. New studies show that .... by Anonymous Coward · · Score: 0

    "New studies show" is the work of the Devil - figuratively speaking.

    I don't know what to say. I don't think - no, there SHOULDN'T be a regulation against bullshit scientific reporting and I don't think there should be a legal mandate to force "journalists" to report "facts".

    My only solution is to point out that studies show that science reporters are big dummies. There momma's are sooooo fat, that they block out the Sun.

    AND studies show that scientists that skip over peer reviewed journals to make public announcements are poo-poo AND froo-froo brained people.

    I have data.

    *Stop this. Producing these "reports" that confuse the public and then we get nonsense about inoculations causing autism or whatever.

    Please stop.

    If you're that desperate for funding that you have to go all AM Radio to get it, then, ..... I don't know what to say.

  9. Cost by Russ1642 · · Score: 1

    Did the study explain why daily low dose aspirin is far more expensive than a full dose? The homeopathic preparation must cost a fortune.

    1. Re:Cost by Anonymous Coward · · Score: 0

      Did the study explain why daily low dose aspirin is far more expensive than a full dose? The homeopathic preparation must cost a fortune.

      Most low dose preparations have an enteric coating. I think that's mostly because of this silly myth of aspirin being hard on your stomach because it's an acid. It causes upper GI bleeding, even when the acid is neutralized.

      Anyway, other than an unneeded coating, there's nothing to stop you from splitting full strength pills, so you can save a few pennies a day.

    2. Re:Cost by Russ1642 · · Score: 1

      Even the ones that aren't coated are more expensive. Hell, an 80mg coated pill is more than twice the price of a 325mg coated pill. The technical term is 'gouging'.

    3. Re:Cost by mcgrew · · Score: 1

      All it takes is a kitchen knife, simply quarter the full dose with it and you have a dose that costs 1/4 of the high dose.

    4. Re:Cost by Anonymous Coward · · Score: 0

      And break the coating, vastly increasing the risk of gastro-intestinal problems.

  10. Not just aspirin! by Samantha+Wright · · Score: 0

    The Daily Mail Helps Prevent Cancer, New Studies Show

    "For years, research has shown that the Daily Mail is beneficial in preventing heart attacks. Now new studies support its ability to prevent cancer as well. The studies, involving dozens of unaware readers over many decades, show reductions of cancer incidence (both short- and long-term) and mortality rate as well as a decrease in metastatic cancer. It still is not known exactly how the Daily Mail and cancer are connected, but those between the ages of 55-60 will now likely consider taking low-dose Daily Mail daily for the remainder of their lives, perhaps just the Sport section."

    --
    Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
  11. I'm for it. by Cazekiel · · Score: 4, Funny

    I was thinking of quitting smoking. Now I'll just take an aspirin with every cig. Problem solved!

    --
    You want to know how to help your kids? LEAVE THEM THE F*&K ALONE. --George Carlin
    1. Re:I'm for it. by 93+Escort+Wagon · · Score: 3, Insightful

      I was thinking of quitting smoking. Now I'll just take an aspirin with every cig. Problem solved!

      If you take the aspirin tablet and use it to plug the filter end of your cigarette, it might actually lower your risk of lung cancer.

      Your risk of choking, on the other hand...

      --
      #DeleteChrome
    2. Re:I'm for it. by Cazekiel · · Score: 1

      Maybe I can cram a multivitamin in there too. Goodbye cancer-risk, hello smoky nutrition! A day's worth of vitamin C, and as much calcium as a glass of milk! Yes, this plan is infallible.

      --
      You want to know how to help your kids? LEAVE THEM THE F*&K ALONE. --George Carlin
  12. The Study Itself Is Fine, Singularity Hub Is Not by eldavojohn · · Score: 4, Insightful

    it's actual, real life, scientific research - published in a well read and respected peer reviewed medical journal.

    I've got no problem with the original research being legit. I have a problem with the original research showing that for this historical data it statistically linked aspirin to reducing the risk of cancer. It didn't show that these people who took aspirin were also more likely to take supplemental vitamins nor did it attempt to show exactly how the aspirin worked its "miracle." Was there a control group? You have to understand that the reason I'm "wee weeing" (whatever the hell that means) singularity hub is that they took totally legit level headed scientific research and they jumped all the way up to this:

    100-Year Old Wonder Drug Now Shown To Prevent Cancer and Heart Attacks

    Now let me ask you, where in the research did it "show" in anyway how this prevents cancer? And the article itself was only worse. It's a statistical study on historical data and from your PBS link, they did it right:

    How Aspirin May Help Prevent Certain Kinds of Cancer

    Do you see the difference here? These singularists or futurists or whatever the hell you want to call them take this, which is like 50% and bump it all the way up to 100% and make it a universal truth. Then they extoll this about how they're living until the end of time and people get caught up in this. It's ridiculous and, yes, I'm going to call this out when I see it. I do call that half-truths and I do call that misinformation. We can be more clear about this and the people PBS interview are.

    That part about the 114 year old man? That wasn't misinformation? The lead in that that was all you need? I was out of line to get annoyed by that?

    --
    My work here is dung.
  13. Aspirin's mechanism of action IS known! by Invisible+Now · · Score: 5, Informative

    The mechanism, at least for colon cancer is known. Aspirin is COX 2 inhibitor. Colon and other cancers have COX 2 receptors on their cell walls. See details at: http://modernrecovery.com/news/7-latest/11-aspirin-reduces-colon-cancer.html

    --

    "Knowing everything doesn't help..."

    1. Re:Aspirin's mechanism of action IS known! by Anonymous Coward · · Score: 2, Informative

      My GI and Cancer doc has me on a low dose of Aspirin (81mg) to try and prevent me from getting Colon Cancer.

      I just started the process this year so I do not know if it is going to help in the long run or not, but we will see.

      I am rated as an extreme high risk for Colon cancer and have been getting colonoscopies since age 30 to watch for and clear out polyps that could become cancerous if not dealt with.

    2. Re:Aspirin's mechanism of action IS known! by Anonymous Coward · · Score: 0

      I think that you should take it easy with the Aspirin, even there is a high risk for getting colon cancer.

      Aspirin is in the group of drugs called NSAID. I read about NSAIDs effects against colon cancer the first time little less than a year ago.
      However, NSAIDs do have the side effect of making your stomach churn out more acid, which can cause an ulcer.

      I was diagnosed with colon cancer last summer, at the age of 35. I got the tumor removed two weeks later. While I was waiting for surgery, I self-medicated myself with a daily dose of ibuprofen (another NSAID). After surgery, I was prescribed lots of diklofenac (yet another, but stronger NSAID) as pain-killer.

      A few months later, I got an ulcer. I almost recovered from that with the aid of medication. I got a new ulcer a few weeks ago that I am now medicating against using stronger drugs.
      I won't take NSAIDs any more. I also used to use diklofenac against migraines, but I have now switched to another drug.

    3. Re:Aspirin's mechanism of action IS known! by Anonymous Coward · · Score: 0

      So the best health advice is to avoid COX in your colon?

    4. Re:Aspirin's mechanism of action IS known! by Invisible+Now · · Score: 1

      Aspirin may be grouped with other NSAIDS, but it is drug unto itself. Like many people I can take aspirin by the fistful if I need pain relief. I always take some everyday like a vitamin. Things to note... Aspirin does not harm the liver like acetaminophen The studies we are all discussing here show that individuals adjust to aspirin and develop a tolerance to any stomach/bleeding effects. Tylenol has spent hundreds of millions of dollars to convince folks that their NSAID ( which is the #1 cause of liver failure in the US) is superior to good old generic aspirin. Without ever demonstrating that Tylenol ( or other NSAIDS for that matter) have all of aspirin's benefits. Best of luck in your recovery,

      --

      "Knowing everything doesn't help..."

    5. Re:Aspirin's mechanism of action IS known! by Anonymous Coward · · Score: 0

      That's pretty much the exact anecdotal evidence i was going to give. I've got the "nice" version of the genetic disorder, so i managed to put off my first colonoscopy until i was 35. When i went in for my second one earlier this week they found that i've "only" grown four new polyps in the last year. So now i'm on the "come in every year" list and the doctor suggested i should start taking daily asprin to see if it helps. Then the very next day while staying home to recover i saw this article, quite a bit of synchronicity.

  14. Inflammation by koan · · Score: 4, Informative

    There are doctors that are going as far as to state that most ailments (heart disease, cancer, arthritis, etc) are cause to some degree by chronic inflammation:
    GIFY
    https://encrypted.google.com/search?client=ubuntu&channel=fs&q=inflammation+and+disease&ie=utf-8&oe=utf-8

    Aspirin reduces inflammation and so helps in all things inflammation related.

    You should check out diet related inflammation as some (if not most) of us have poor dietary habits OR eat to much.
    https://en.wikipedia.org/wiki/Inflammation

    --
    "If any question why we died, Tell them because our fathers lied."
    1. Re:Inflammation by 93+Escort+Wagon · · Score: 1

      You should check out diet related inflammation as some (if not most) of us have poor dietary habits OR eat to much.
      https://en.wikipedia.org/wiki/Inflammation

      I'm sure you'll pardon me if I don't take a crowd-sourced document as gospel when it comes to health advice.

      --
      #DeleteChrome
    2. Re:Inflammation by Anonymous Coward · · Score: 0

      Yes heavens forbid you actually Google before replying.
      http://abcnews.go.com/blogs/health/2012/03/22/obesity-might-lower-cognitive-function/
      http://www.ncbi.nlm.nih.gov/pubmed/19236339

      The above inflammation related.

      Smart to question sources ignorant to stop researching.

    3. Re:Inflammation by sackbut · · Score: 2
      Inflammation is an immunological reaction by the body to a perceived insult. The immune system protects the other cells from bacteria, viruses, etc but can be damaging to normal uninvolved areas. The insult can be physical (ie: radiation), chemical (ie: acid) or even the inflammatory cascade switched on due to a malfunction of the switching mechanism (autoimmune). Although inflammation is not the direct 'cause' of a disease (except perhaps in autoimmune disease) it is often the 'cause' of the tissue injury and body response that is noticed (ie: signs and symptoms).

      The body does have an inflammatory response to most cancers (uncontrolled and uncoordinated cell proliferation).

    4. Re:Inflammation by Anonymous Coward · · Score: 1

      I'm sure you'll pardon me if I don't take a crowd-sourced document as gospel when it comes to health advice.

      There's this nifty section at the end of the page that points to a whole metric fuckload of non-crowdsourced documents that went into creating the crowd-sourced version. Feel free to peruse at your leisure.

  15. Re:With government healthcare, expect more of this by Anonymous Coward · · Score: 0

    With huge deficits and government healthcare, expect more of this. Suddenly, women don't need mammograms every year. PSA tests are harmful. Off-patent drugs that cost pennies a pill are suddenly the best thing to prescribe.

    This is a good thing up to a point. It's a relief from the CYA medicine that gives you a $5000 workup for tennis elbow. There is of course, justifiable fear that we swing too far in the other direction and start seeing new studies that show it's OK to wait 3 months for bypass surgery.

    Well, I'm pretty sure that waiting three months for bypass surgery substantially lowers your risk of dying from cancer.

  16. Maybe Willow Bark instead by doston · · Score: 1, Interesting

    Aspirin is already converted to salicylic acid (I think), so you may be better off (study this) with the natural precursor 'Willow Bark', that way the liver converts the substance to salicylic acid and doesn't take a pounding from aspirin. Don't know if it works (obviously), but if I wanted to take aspirin daily, I'd take it that way instead, since it may be kinder and gentler on your system. You can die from other things besides cancer and heart disease...like a failed liver or thin blood.

    1. Re:Maybe Willow Bark instead by omnichad · · Score: 1

      Wait, so your liver has to convert to salicylic acid AND dispose of it later? That sounds like doubling the load on the liver to me.

    2. Re:Maybe Willow Bark instead by doston · · Score: 1

      Liver probably does the conversion at its leisure, instead of having the salicylic acid dosed into the blood stream all at once, but I'm just guessing. It's something you'd probably want to research, if you plan to take a dose of aspirin every day. Can't imagine there isn't a downside to either, but natural remedies tend to have less side effects and this one is so obvious (aspirin was isolated from willow bark), that it would be tough for me to ignore. I don't plan to take a daily dose of either.

    3. Re:Maybe Willow Bark instead by Anonymous Coward · · Score: 1

      1. Dose control. Actual medicines are dose controlled. When you take 300mg of aspirin that's what you get. Willow bark? The Willow tree doesn't care how much of this drug is present in each flake of bark, why should it? So your dose is uncontrolled. Maybe you get 25mg today and 500mg tomorrow. Is that too much? Who knows.

      2. Purity. The drug manufacturer takes care to ensure your Aspirin just has Aspirin in it. Not lead leached from an old mine, not some undetermined lichen, not anything else that might be in the bark of some tree.

      3. "Natural remedies tend to have less side effects" is gibberish. Most "natural remedies" that do anything at all have plenty of side effects, naturopaths just don't care (got your money already, too bad if you get sick and die).

      4. It's actually the willow bark that contains salicylic acid and Aspirin that is acetylsalicylic acid so you couldn't even keep this straight

    4. Re:Maybe Willow Bark instead by mutube · · Score: 5, Informative

      Aspirin is already converted to salicylic acid (I think), so you may be better off (study this) with the natural precursor 'Willow Bark'.

      You've got this exactly backwards (unfortunately this was also about the only time you were 'exact' in your entire post).

      If I wanted to take aspirin daily, I'd take it that way instead, since it may be kinder and gentler on your system.

      So you essentially have no idea. But it being natural feels all warm and fuzzy so you will do that instead of basing your decisions off nasty pointy facts.

      You can die from other things besides cancer and heart disease...like a failed liver or thin blood.

      Or self-medicating with incorrectly dosed quanties of active drugs derived from an poorly regulated source.

    5. Re:Maybe Willow Bark instead by doston · · Score: 1

      I'm happy to read any sources you might have.

    6. Re:Maybe Willow Bark instead by Anonymous Coward · · Score: 0

      I think, that's not necessarily how it works. It could be that the precursors to aspirin which are in Willow bark are less toxic than the aspirin itself. Kind of like how the metabolites of alcohol are more toxic than the alcohol itself.

    7. Re:Maybe Willow Bark instead by mutube · · Score: 1

      I'm happy to read any sources you might have.

      Sources for what?

      Aspirin metabolism is outlined here, with a bit more here. Salicylic acid is derived from willow bark (the name Salix from Latin for willow) and is the active form of the drug, resulting predominantly from first pass metabolism in the liver - although some also occurs in the intestine.

      Or, did you want a reference for my criticism of your wooly thinking? My only source for that was your post, which I referenced and quoted. For all I know you could be usually quite sharp. If you have other examples of misinformed decisions based on warm-and-fuzzy concepts I will of course be happy to take a look.

      Or, were you looking for a reference to the suggestion that taking excessive quantities of some drugs may cause ill effects? I think that's well established fact. Even your own inference that willow bark would be 'better' was based on that very idea. If we're going to accept these things have pharmacological action (which they do) it follows that inconsistent or excessive dosing is either going to limit effectiveness or cause harm. Natural products are intrinsically variable, ergo replacing aspirin with willow bark is introducing variability with the potential to limit effectiveness or cause harm.

      I'm not arguing that willow bark "wouldn't work" I'm arguing against your suggestion that it would be in any way better. If you still genuinely think it would be I think the onus is on you to provide both a coherent argument why that is the case - and references to support it.

    8. Re:Maybe Willow Bark instead by doston · · Score: 1

      Your oddly angry and needlessly insulting response aside, what I was referring to were sources for willow bark metabolism vs aspirin. After a 20 second Google search, I find you're wrong about willow bark's metabolism and you're wrong about their having the exact same active constituents. http://www.ncbi.nlm.nih.gov/pubmed/21226125 Sounds like willow bark has anti inflammatory mechanisms outside the small amount of salicylic acid it contains. Anti inflammatory=Good. Maybe even more benefits than aspirin and almost definitely the same, especially if thinking of daily low dose aspirin for prevention. There are standardized versions of willow bark now, so I don't think the dosage always has to be so variable. Personally, I'd prefer to take a natural version of pretty much anything. Must stem from my (highly justified) distrust of the pharmaceutical industry.

    9. Re:Maybe Willow Bark instead by mutube · · Score: 1

      Apologies for the narky previous post - had a long day and was in a generally grumpy mood. Slashdot could do with a 'you sound like a dick' filter.

      In that paper it refers to the quantity of sialicin (pro-drug) in willow bark being insufficient for the analgesic effect but doesn't make reference to the quantity of active siacylic acid which is odd. It's a component of normal metabolism so is going to be there. The conversion of siacylic acid to acetylsiacylic acid (as found in aspirin) is to protect the stomach lining and help absorbance. Although it states the willow bark has lower GI effects at doses for analgesia given the levels of sialicin (and siacylic acid?) are much lower then that's probably not surprising. Unfortunately I can't access the paper to find out how they configured the dosing. On the other mechanisms of anti-inflammatory action - that's great. It's worth investigating what those constituents are so we can understand them - and then synthesise them into a pill. Anti-inflammatory is usually good (especially in the realm of cancers) - but the OP was about the beneficial effects of aspirin itself (single active drug) not anti-inflammatories in general. So whether willow bark with it's low concentrations of sialicin/siacylic acid is equally effective is uncertain. I would agree it is definitely worth investigation - the position of aspirin in the study is solely due to it already being used regularly long term for all those other things.

      Healthy distrust for any 'industry' is a good idea but aspirin is off patent and hardly a cash cow. Do you hold the same distrust for producers of herbal remedies? I'm assuming your not going to be growing the trees yourself. If we all switched over to using willow bark the companies wouldn't look very different at all. On the upside we would have a lot more trees.

      Apologies again for the tone of the previous message.

    10. Re:Maybe Willow Bark instead by doston · · Score: 1

      Eh, not at all. I'm snarky as all get out sometimes. In fact, I am beginning to hold the same distrust for companies that produce certified organic and 'natural' products. As mass production and shareholders get involved, watch out.

  17. Request by Anonymous Coward · · Score: 0

    In the future with submissions of studies like this -- can we get a caption reading:
        "Studies funded by bayer or subsidiaries" or
        "Studies not funded by bayer or subsidiaries"

    I read it, but the first snap thought in my head was "I bet we've got another case of conflict of interest that should probably result in throwing out the science and running the numbers elsewhere"

    1. Re:Request by Neil+Boekend · · Score: 1

      Flag it as such.

      --
      Well, I might have a way, but it only works on a semi spherical planet in a vacuum.
  18. ASPRIN MADDNESS by Bigsquid.1776 · · Score: 1, Funny

    Don't use that devil Asprin... Millions of lives have been ruined by junkies trying to "numb themselves out" with that devil Asprin. Dealers have these junkies hooked. Asprin is NOT COOL. Just say NO!

  19. Just another hope for an easy way out by Anonymous Coward · · Score: 0

    This does nothing but to continue to motivate people to eat crap, leave a sedentary life and have high hopes for an extended healthy life.
    Just pop in an aspirin daily and you are OK. Sure. Big Farma is so wonderful, they really care about our health, just like the food industry.

    1. Re:Just another hope for an easy way out by treeves · · Score: 1

      Really? Big Pharma has nothing to gain by promoting aspirin, of all things. If anything they should want to squelch this research since buying aspirin instead of their expensive statins, anti-cancer drugs, chemo drugs, etc. etc. is less $$ for them.

      --
      ...the future crusty old bastards are already drinking the Kool-Aid.
  20. I'm 33 by DanZ23 · · Score: 3, Insightful

    And I already believe in the benefits of taking an aspirin a day right now. To me there's just too much correlative evidence to conclude otherwise.

  21. Inflammation by ThatsNotPudding · · Score: 2

    Seems like a lot of maladies have a root cause of inflammation.

  22. Whew! by Anomalyst · · Score: 1

    I initially read that as "Aspirin Helps Prevent Career"
    and became jittery as I imagined an insidious Apple or Microsoft plot to limit my potential for advancement by foisting their products on us had been uncovered.

    --
    There is no right to feel safe thru security vaudeville at the expense of everyone's freedom, privacy and tax money.
  23. For Further Study by carrier+lost · · Score: 1

    I wonder what the results are with subjects whose primary use of aspirin is to treat hangovers?

    I mean, not me necessarily... just good to know, y'know?

    No, really.

  24. In other news ... by Lazy+Jones · · Score: 1
    ... a daily high (*) dose of arsenic has also been shown to prevent cancer and clogged arteries.

    (*) lethal

    --
    "I love my job, but I hate talking to people like you" (Freddie Mercury)
  25. Aspirin is useful for suicide too by Anonymous Coward · · Score: 2, Funny

    I had a friend who wanted to commit suicide by taking 500 aspirin.

    But after the first two he felt better.

  26. Re:The Study Itself Is Fine, Singularity Hub Is No by Ameryll · · Score: 3, Funny

    Obligatory XKCD reference: http://xkcd.com/882/

  27. Re:The Study Itself Is Fine, Singularity Hub Is No by krotkruton · · Score: 4, Interesting

    I agree with you on a lot of points, but this study was more than just another correlation study like those that link high levels of vitamin D in subjects to reduced risks in cancer. This was a meta-analysis, which is meant to eliminate some of that bias by taking many studies (51 if I read correctly) and weighing them based on their merits and processes to look for statistical significance. Sure, it's not a perfectly executed double blind, but it's still an important study and the results shouldn't just be thrown out.

  28. What I find amazing... by Anonymous Coward · · Score: 0

    is that anybody publishes a study on a drug that is dirt cheap. I don't know if aspirin would pass FDA muster today as a new drug. But I hate to think what the drug companies would claim about aspirin and what they would charge for it if it were a new drug. I take a baby aspirin a day, I have for years, I'm 56 years old. I used to take a whole aspirin as it was cheaper that way. I also take a multivitamin in case I don't eat right. Don't forget to low vitamin D and magnesium have been linked to depression and may not be provided by multivitamin.

  29. Palin who? by pigwiggle · · Score: 1

    The president introduced me to that one.

    http://www.youtube.com/watch?v=mTVjab2cHgk

    --
    46 & 2
  30. moneymaking motherf**kers by Anonymous Coward · · Score: 0

    Bayer: Cha- CHING!

  31. Re:The Study Itself Is Fine, Singularity Hub Is No by Anonymous Coward · · Score: 0

    If you watch the video on PBS they interview a doctor and he says it appears that aspirin suppresses the body's creation of certain enzymes that are known to cause cancer to grow and metastasize,

  32. Statistical Abuse by Anonymous Coward · · Score: 0

    Such studies are an abuse of statistics. Using statistics to draw a conclusion about cause and effect is a nonsense. The only way to properly draw a conclusion about what aspirin might be capable of doing is to follow the actual chemistry and biology and show how and why certain things happen.

    Statistics can be used to show that everybody who drinks water ends up dying. So does this mean that water causes death?

    Must be research funding season again.

  33. how aspirin and cancer are connected by hAckz0r · · Score: 1

    There was a study just last year that stated the same thing about benadryl (Diphenhydramine), but that study went out on a limb and stated that by reducing the swelling the immune system was able to get into the affected area and remove the cancer. By that theory, anything that reduces swelling should reduce the chance of cancer, so why should asprin be any different?

  34. It was good while it lasted by overshoot · · Score: 1

    So much for blood donations.

    --
    Lacking <sarcasm> tags, /. substitutes moderation as "Troll."
  35. Brought to you by Bayer AG by RocketRabbit · · Score: 1

    Thankfully there are no disclosure requirements for medical research, so we don't have to worry about who funded these studies.

  36. But ... by pepty · · Score: 2

    There was no significant difference in all cause mortality. So overall, the people who were assigned aspirin are living as long as the people who weren't.

  37. the wee weeing by pigwiggle · · Score: 1

    is where you implied the research was suspect because of the funding citation - your suspicion apparently confirmed by the outlet carrying the news. If your beef was really with the reporting on the research, then you would have drawn distinctions between the research and the article. But you didn't. You clearly did have a problem with the original research being legit. Until it was pointed out it was, in fact, legit. Now your problem is just the bad reporting. Fine then.

    --
    46 & 2
  38. My bet is on gut flora by BlueCoder · · Score: 1

    Aspirin is probably antagonistic of certain bacteria in the gut that produce waste products that promote cancer or it could promote good gut bacteria that eat aspirin and turn it into waste products that are good for you. To demonstrate that aspirin in and of itself in the blood stream is preventative of cancer you would have to do studies where it is administered intravenously.

    I can't wait until we can actually decode DNA like a computer program and run simulations. Not just our DNA but the DNA of microbes in the gut. Then we will be able to better able to understand the complex interactions rather than simply doing statistical studies of multiple individuals. Modern medical research is comparable to research in particle physics where they take two thing and smash them together to see what falls out.

  39. WTF? by funkboy · · Score: 1

    Seriously, what the fark is this doing on ./ ?

  40. Re:The Study Itself Is Fine, Singularity Hub Is No by treeves · · Score: 2

    Even "may help" still suggests a causal link, where none has been demonstrated. Such language can confuse a lot of people and can be avoided but it takes some effort that space-saving and lazy journalists and headline writers may not wish to exert.
    See http://www.healthnewsreview.org/2012/03/please-read-our-primer-on-observational-studies/

    --
    ...the future crusty old bastards are already drinking the Kool-Aid.
  41. Consider side effects before taking by Anonymous Coward · · Score: 0

    Whatever you do, don't just start taking aspirin because another study makes it sound good. The standard advice is to discuss it with your doctor first. Even talking with your doctor isn't foolproof. I started taking aspirin on my doctor's advice for the normal heart health reasons. Two years later I ended up in the hospital for two days with a bleeding ulcer. I was not infected with h. pylori so the diagnosis was that the ulcer had been caused by the aspirin, which is a known side effect.

  42. Re:The Study Itself Is Fine, Singularity Hub Is No by Anonymous Coward · · Score: 0

    I'm not sure a 'causal link' has been demonstrated between smoking and lung cancer, has it? Obscure language can also defuse an important message that you are trying to get out to non-experts.

  43. Re:The Study Itself Is Fine, Singularity Hub Is No by Anonymous Coward · · Score: 0

    You left out it only reduces your risks by 10-15%. If the study was well thought out, or was done as you described, but as most studies it probably was not.

  44. Re:The Study Itself Is Fine, Singularity Hub Is No by yarbo · · Score: 2

    'It didn't show that these people who took aspirin were also more likely to take supplemental vitamins nor did it attempt to show exactly how the aspirin worked its "miracle."'
    Supplemental vitamins don't increase life expectancy

  45. Re:The Study Itself Is Fine, Singularity Hub Is No by slasho81 · · Score: 1

    Obligatory PhDComics.