Slashdot Mirror


Scientists Turn Skin Cells Into Beating Heart Muscle

An anonymous reader writes "By taking skin cells and turning them into stem cells, a technique that is already well known, researchers at Technion Israel Institute of Technology were able to generate beating heart cells — a medical first. 'We have shown that it's possible to take skin cells from an elderly patient with advanced heart failure and end up with his own beating cells in a laboratory dish that are healthy and young — the equivalent to the stage of his heart cells when he was just born,' Lior Gepstein, study author and professor of medicine said."

121 comments

  1. More of this, please by geekoid · · Score: 1

    Hurry up already. I want to see easily replaceable hearts in MY life time...also ever other organ.
    IN fact, just full body clone replacements and transplant my head.
    .

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    1. Re:More of this, please by WillDraven · · Score: 2

      I'll be happy as long as modern medicine can keep me alive until we perfect mind uploading. Sometimes I get really sick of being a bag of meat.

      --
      This is my sig. There are many like it but this one is mine.
    2. Re:More of this, please by geekoid · · Score: 1, Interesting

      Great, so there is a copy of you on the internet, then what? is the meat you going to go kill itself? Or you can all create one big conglomerate of personalities, which would then stagnate.
      Pass.

      The machine alone is too limiting.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    3. Re:More of this, please by Anonymous Coward · · Score: 0

      So you want to be a bag of silicon instead?

    4. Re:More of this, please by WillDraven · · Score: 4, Interesting

      Personally, I'm hoping that we get back on track with space travel, and then I can upload myself into an interstellar space probe. If nano-tech gets good enough, you could maybe even reconstitute a physical body if you find someplace interesting to land. With an electronic mind, you could alter your perception of time so the boring parts of floating between stars for years would only last a few minutes subjectively.

      --
      This is my sig. There are many like it but this one is mine.
    5. Re:More of this, please by kermidge · · Score: 2

      Amen. If they could use these cells to repair heart and vessels, I'd be second in line. And if this technique could be adapted to various eye parts, sign me up. Although my curiosity exceeds optimism I'd like to stick around a bit to see what happens.

    6. Re:More of this, please by Spiked_Three · · Score: 4, Funny

      My head is ugly. I want all new please.

      --
      slashdot troll = you make a compelling argument I do not like the implications of.
    7. Re:More of this, please by Anonymous Coward · · Score: 0

      That would make a great movie...

    8. Re:More of this, please by jamesh · · Score: 2

      I'll be happy as long as modern medicine can keep me alive until we perfect mind uploading. Sometimes I get really sick of being a bag of meat.

      What if someone illegally downloads you? That could really hurt!

    9. Re:More of this, please by Nidi62 · · Score: 1

      What if someone illegally downloads you? That could really hurt!

      Yeah, every time Lucy Liu got illegally downloaded her head got shocked. Certainly looked painful.

      --
      The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
    10. Re:More of this, please by Adriax · · Score: 4, Funny

      The toggle for the host computer's perception speed had better resemble a 386SX-16 turbo button or I wouldn't even bother.

      --
      I don't suffer from insanity, I enjoy every minute of it!
    11. Re:More of this, please by geekmux · · Score: 1, Interesting

      Hurry up already. I want to see easily replaceable hearts in MY life time...also ever other organ. IN fact, just full body clone replacements and transplant my head. .

      Sure, no problem! I'm certain we'll have all that technology and more within the next 30 - 50 years.

      Oh, I'm sorry, did you expect insurance to pay for ANY of that shit? Ha! Good luck. Might as well forget that retirement villa, you're gonna blow your 401k just trying to save your ticker, because even at that age, insurance will still be just as corrupt, and the medical industrial complex will continue its obscenely profitable model of treating instead of curing.

    12. Re:More of this, please by Genda · · Score: 1

      Sadly yes, he wants to be a bag of Silicon, inflating some some nymphet's bust line.

    13. Re:More of this, please by Lynchenstein · · Score: 3, Funny

      If they could clone and replace "certain" organs with, oh, say, perhaps, LARGER versions, they could pay for all future research with the proceeds of this technique.

      Of course *I* don't need this, but I'm sure *others* might...

    14. Re:More of this, please by Anonymous Coward · · Score: 0

      until you are hit by a magnetic storm or such and your memory is wiped. you'd be just as fragile as all computes are.

    15. Re:More of this, please by barv · · Score: 1

      Hurry up already!

    16. Re:More of this, please by interkin3tic · · Score: 1

      Wrong forum: write to your legislators that you want the NIH to receive more funding for research.

    17. Re:More of this, please by Anonymous Coward · · Score: 0

      Can you get closer to a tit?

    18. Re:More of this, please by Anonymous Coward · · Score: 0

      My wife had Kidney failure after having our first ( and only child) about 13 years ago. Her mother donated a kidney to her after 4 year on Dyalysis. She pops many pills each day to keep her from rejecting it and those pills will eventually kill her.
      The donated kidney will hopefully last abotu 20- 25 years but then what? She will be 50 years old and then go on another waiting list?

      This sort of technology will save many lives and I am waiting fo rthe medical advances to create a NEW kidney that will not require so many drugs to manage!

    19. Re:More of this, please by joocemann · · Score: 3, Informative

      This work hs been going on in an adacent lab for a while now.... very promising to hear results like that.

        http://m.circres.ahajournals.org/content/107/9/1042.full

    20. Re:More of this, please by harley78 · · Score: 1

      If he got what he wanted that wouldn't be a problem as he'd probably have another 50 some odd years. BTW, some people can pay for this shit without insurance. We don't all live paycheck to paycheck. Other countries besides the USA have decent prices also.

    21. Re:More of this, please by harley78 · · Score: 2

      Oh, I get it! You mean the Liver!

    22. Re:More of this, please by Anonymous Coward · · Score: 0

      Even if you could upload your mind, you probably would still be a bag of meat. After all, it's only a copy.

    23. Re:More of this, please by K.+S.+Kyosuke · · Score: 3, Funny

      The toggle for the host computer's perception speed had better resemble a 386SX-16 turbo button or I wouldn't even bother.

      Yes, but if you're already inside the computer, how do you press the button?

      --
      Ezekiel 23:20
    24. Re:More of this, please by thoughtsatthemoment · · Score: 1

      I think there is one part in your brain that you don't want to replace. If you do, you'd effectively have committed suicide. (hint the most import part of the computer is ...).

    25. Re:More of this, please by thoughtsatthemoment · · Score: 1

      typo: import -> important

    26. Re:More of this, please by blackest_k · · Score: 2

      In a heart attack, the heart muscle is deprived of oxygen and begins to die, and later becomes scar tissue, which leaves your heart with a reduced capacity to pump blood round your body.

      This could potentially be the chance to regenerate the Heart Muscle repairing the damage.

      The 50% rate after an initial heart attack is around 6 to 8 years (30% die from an initial heart attack) with a 25% chance of death in the first year. Quite depressing, although after year 1 its 3% compared to 1.5% for normal folk. Obviously the greater the damage caused by the blockage the more likely it is to kill you sooner rather than later. In the case of severe damage maybe stem cells might be an effective treatment and well worth the risk of cancer later in life.

      It is worth remembering that it takes 20 - 30 minutes before the heart muscle begins to die so if you think you may be having a heart attack go for treatment and proper diagnosis fast. Leaving it for a few hours might not kill you but it will reduce your long term chances and quality of life.

      For me it just felt like i couldn't catch my breath, for a friend of mine his pulse was 43 I forget his BP but 43 is very low for a fat old bloke, I got him to a Dr against his wishes (he had an appointment 3 hours later he wanted to wait for that) and he now has a triple bypass and a pacemaker. 2 years on he is still ok but waiting would have killed him.

      My health is pretty good because i had minimal damage i have 2 stents fitted which work really well and a noticeable increase in energy levels immediately after. The stents are fitted from your groin and 3 days later i was out of hospital. A heart attack isn't necessarily painful some people will feel a pain in the left arm or pressure on their chest sometimes it might feel like indigestion or heart burn.

                   

    27. Re:More of this, please by RivenAleem · · Score: 1

      OMG! Mind-rebooted.

    28. Re:More of this, please by Anonymous Coward · · Score: 0

      I live in the UK but thought the 401k was for retirement. If organs are being replaced and you are living longer, then there is no retirement, there is no career advancement, there will have to be wholesale sterilisation to prevent a population explosion, the rich will own private armies to prevent any of their wealth from being dissolved and the poor will be forgotten.

    29. Re:More of this, please by Anonymous Coward · · Score: 0

      Given my proclivity for bacon I bet I taste great! I'll upload to the machine consciousness and then make myself a nice BBQ me sandwich. Mmmmm...

    30. Re:More of this, please by virgnarus · · Score: 1

      This should be effective at accomplishing that.

    31. Re:More of this, please by JazzLad · · Score: 1

      You forgot to add "Spoiler Alert" - now we know how the movie ends!

      --
      "If you have nothing to hide, you have nothing to fear." - Every fascist, ever
    32. Re:More of this, please by Anonymous Coward · · Score: 0

      He wants to be fondled by other men?

    33. Re:More of this, please by kermidge · · Score: 1

      Good info, glad you're still here to bring it. The irregular symptoms are scary - how's one to know and make the call?

      I'm of mixed mind on stents, have seven now. Look like pick-up-sticks on X-ray. Much rather they could Rotor-Rooter or rebuild the pipes.

    34. Re:More of this, please by GNious · · Score: 1

      Sign me up!

    35. Re:More of this, please by skids · · Score: 1

      With an electronic mind, you could alter your perception of time so the boring parts of floating between stars for years would only last a few minutes subjectively

      It's all fun and games until someone loses an aeon.

    36. Re:More of this, please by nanoflower · · Score: 1

      Except for the fact that we already have EMP hardened electronics. Plus just the other day there was an article about nano-vacuum tubes that are immune to most (all?) electromagnetic interference. Clearly a long term probe with a human mind aboard would be protected against such storms if it is at all possible.

    37. Re:More of this, please by blackest_k · · Score: 1

      If you can do it check the pulse if that is abnormal it is a problem of some sort. I'd say play it safe, I guess it depends where you are as to what you do. In ireland it would probably cost you if you don't have private insurance or a medical card maybe 60 euro if your just checked out by a dr in the UK you can just go and be checked, in the usa well that might be a bigger problem.

      Stents are actually cheap for what they do, In 2009 I know a Dr wasted a stent and it was about 600 euro worth of stent he scrapped. It is a relatively cheap procedure and as the alternative is cutting open your chest under a general anaesthetic i'll go with the stent while it helps me.

             

  2. So it only goes to follow... by l0ungeb0y · · Score: 1

    That next week they'll announce the ability to regenerate an entire body from skin cells in 10 to 20 years, depending on funding of course.
    Lots and lots of funding -- preferably in the form of grants and endowments.

    1. Re:So it only goes to follow... by Anonymous Coward · · Score: 1

      Speaking of endowments - penis enlargement anyone?

    2. Re:So it only goes to follow... by Genda · · Score: 1

      This is going to be stupid... a generation of Alpha Males, rooted to the spot by their 400 lb, 6 foot appendages... Just because you have the money and science makes it possible doesn't mean you should do it!

    3. Re:So it only goes to follow... by Anonymous Coward · · Score: 1

      Rooted to the spot? You forgot about wheelbarrows.

    4. Re:So it only goes to follow... by tomhuxley · · Score: 3, Funny

      Finally a real use for Segways!

    5. Re:So it only goes to follow... by Xaedalus · · Score: 1

      No, what's going to be stupid are all the bimbos who are going to rush out and get their hoo-hoos altered to be able to accept said 400lb 6 foot appendages. Gaping gateway to Hell will take on a whole new meaning.

      --
      Here's to hot beer, cold women, and Glaswegian kisses for all.
  3. Re:WHAT WHITE PEOPLE ARE HIDING! by Nidi62 · · Score: 1, Funny

    Can we bring back the my clean pc guy? At least his spam posts are shorter and more entertaining to read.

    --
    The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
  4. A question for the bio geeks.. by wbr1 · · Score: 4, Interesting

    By taking skin cells and turning them into stem cells as the precursor to other cell lines that match the patients genetic makeup. are you increasing the chances of cancer?
    In my certainly uninformed view, skin cells are exposed to more radiation, thus more likely to have replication errors in their DNA, then adding the stress of modifying the cell to another form, I wonder what that does to it from a replication standpoint. It is nice to have fresh heat muscle I am sure, but to suddenly find yourself with melanoma in the heart would be a bummer.

    --
    Silence is a state of mime.
    1. Re:A question for the bio geeks.. by dgatwood · · Score: 3, Informative

      Unless you wear string bikinis, most folks have plenty of skin that never sees the sun. That said, I would expect a cheek swab (the mouth variety) to be a more common way to get those cells.

      --

      Check out my sci-fi/humor trilogy at PatriotsBooks.

    2. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      you could take skin cells from where the sun doesn't shine.

    3. Re:A question for the bio geeks.. by cvtan · · Score: 4, Funny

      That means you could literally make a politician out of a horses ass!

      --
      Sorry, but gray text on gray background is making my eyes bleed.
    4. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      As a completely true and not funny story, I had a friend who got skin cancer there. So the sun doesn't have to directly shine somewhere for you to get cancer there. o.0

    5. Re:A question for the bio geeks.. by Kurofuneparry · · Score: 5, Informative

      Biochemist medical student here. Propagating genetic errors is certainly a concern here, but the same concerns exist for genetic transfer in breeding generally. While skin cell are exposed to more radiation, the cells preferred for sampling here are typically from buccal (mouth) sources or are relatively deeper than the layers where most melanoma form.
      Honestly, the more prime concerns are with imperfect "stemming" or imperfect conversion to heart cells.
      Then again ... I'm and idiot ....

      --
      ...... and idiots rule the world....
    6. Re:A question for the bio geeks.. by geekoid · · Score: 5, Insightful

      No.

      If it were true, so what? You need a heart replacement or you will die, soon. If the procedure might give you cancer in 20 years, isn't that still a good trade?

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    7. Re:A question for the bio geeks.. by RabidReindeer · · Score: 4, Insightful

      That means you could literally make a politician out of a horses ass!

      That's just a circular exercise. You end up with the same thing you started with.

    8. Re:A question for the bio geeks.. by ColdWetDog · · Score: 4, Informative

      At any rate, this is early on in the program. Nobody is making new hearts just yet. Cancer certainly is an issue but only one of many potential problems.

      The abstract in case anybody cares. The real article is behind the usual paywall. Grrr.

      --
      Faster! Faster! Faster would be better!
    9. Re:A question for the bio geeks.. by jamesh · · Score: 1

      you could take skin cells from where the sun doesn't shine.

      For the stereotypical slashdotter, that's any part of the body ;)

    10. Re:A question for the bio geeks.. by ChrisMaple · · Score: 1

      So the place of choice is where the sun doesn't shine?

      --
      Contribute to civilization: ari.aynrand.org/donate
    11. Re:A question for the bio geeks.. by Sulphur · · Score: 1

      So the place of choice is where the sun doesn't shine?

      Are you ignoring the advances in fiber optics?

    12. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      Then again ... I'm and idiot ....

      At least you didn't get that part wrong!

    13. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      By taking skin cells and turning them into stem cells as the precursor to other cell lines that match the patients genetic makeup. are you increasing the chances of cancer?

      In my certainly uninformed view, skin cells are exposed to more radiation, thus more likely to have replication errors in their DNA, then adding the stress of modifying the cell to another form, I wonder what that does to it from a replication standpoint. It is nice to have fresh heat muscle I am sure, but to suddenly find yourself with melanoma in the heart would be a bummer.

      Lets say your cancer risk increases 10 fold. That would be, maybe 1%. If you have advanced heart failure it is worth the risk.

    14. Re:A question for the bio geeks.. by Biotech_is_Godzilla · · Score: 3, Interesting

      I'd agree about the imperfect stemming/heart cell conversion thing, but not with this:

      Propagating genetic errors is certainly a concern here, but the same concerns exist for genetic transfer in breeding generally.

      They're not exactly the same concerns. 'Normal' somatic cells, cells of the body which aren't stem cells, have a much higher capacity for surviving with DNA damage in their genomes than stem cells. This is because they have stopped growing & proliferating and hence stopped replicating their DNA, and a major method by which DNA damage is detected in the cell is by "testing whether DNA replication can occur". When DNA replication fails or is particularly difficult there's a good chance a proliferating cell (i.e. stem cells) will activate DNA damage checkpoints and die or senesce (stop growing permanently).

      The methods used to make "stemmed" cells (induced pluripotent stem cells) usually involve introducing some oncogenes which ultimately mess up activation of the DNA damage checkpoints. Also, the genes that are introduced during the process of "stemming" are randomly scattered into the genome, potentially inserting into and knocking out the cell's tumour suppressor genes, so cells which may already be in a DNA-damaged state can be further damaged while being deliberately converted to a highly proliferating state. The process selects for cells which can proliferate even when damaged, which is not ideal as far as preventing cancer is concerned. New methods, using drugs and not the introduction of oncogenes, have been produced, but I don't think they're commonly used yet (correct me if I'm wrong, someone).

      I don't pretend to understand what's unique about how DNA damage is dealt with during sex to prevent mutations being propagated to the next generation. I'm not sure that much work has been done on it, but germline sperm and egg-producing cells are stem cells, so damage isn't likely to be that well tolerated in them, and if sperm is very damaged it's likely to be inviable and won't lead to conception. I had to go off and research this to have something to say about it, during which I found the following tidbit: having sex/ spanking off once a day gets rid of damaged sperm and seems to be a way of maintaining a bloke's fertility in tip-top condition. So blokes are probably biologically programmed to masturbate, in case you needed an excuse!

    15. Re:A question for the bio geeks.. by ThatsNotPudding · · Score: 3, Funny

      Unless you wear string bikinis, most folks have plenty of skin that never sees the sun.

      Taint: is there nothing it can't do?

    16. Re:A question for the bio geeks.. by Kurofuneparry · · Score: 3, Informative

      While you are correct about many of the concerns from the stemming process, I was mainly talking about somatic mutations (like those caused by gamma radiation for example). The statement I made previously about these somatic mutations propagating no more in stemming than in breeding is still true. Also, the proto-oncogene concern is one that current research is already working toward limiting.
      My main concern with your statement is the argument that stem cells are MORE susceptible to random mutation than somatic cells. This is simply false. You argued that decreased activity is a protective attribute than for stem cells. In fact, most stem cells in the human body are LESS active than somatic cells as somatic cells do the work and (monopotent) stem cells like osteoprogenitor cells are mainly there to replenish and preserve genetic information. It's a biological axiom that sex cells (sperm and ova) have the highest importance in preserving genetic integrity and that's what we see experimentally: the sex cells have BETTER preservation of information, not worse.
      .... Then again ..... I'm an idiot ....

      --
      ...... and idiots rule the world....
    17. Re:A question for the bio geeks.. by DeadCatX2 · · Score: 1

      It's a biological axiom that sex cells

      It's also a marketing axiom too. *rimshot*

      --
      :(){ :|:& };:
    18. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      some ill conceived comment about the fact that you said 'rim' in the same post as sex

    19. Re:A question for the bio geeks.. by Kurofuneparry · · Score: 1

      You, sir, win all of the internets.
      ... Then again .... I'm an idiot .....

      --
      ...... and idiots rule the world....
    20. Re:A question for the bio geeks.. by Biotech_is_Godzilla · · Score: 1

      Yeah, I was talking about somatic mutation, such as that caused by any form of ionising radiation, reactive oxygen species, etc. etc. Also, I already said they were working towards limiting the oncogenes issue, but it wasn't yet in wide use, and finally, I wasn't saying stem cells are more susceptible to damage than somatic cells, I was saying somatic cells can take a higher load of DNA damage before detecting it. And yes, that does mean that they can survive better in the presence of more DNA damage (i.e. DNA damage is left in the genome without being dealt with) whereas in stem cells the same level of damage is either repaired or the cells die or senesce. Somatic cells can survive in the presence of more damage. I don't know what you think I argued as your grammar makes no sense at that point, but where I said damage is not likely to be well tolerated in sex cell progenitors I meant that damage will not persist in these cells - they will either repair it or die, unlike somatic cells which sit around with damaged genomes until you convert them to stem cells, carrying all that damage through the stemming process.

      I'm not being funny, mate, but what you think is a bone of contention from my original post isn't - in fact I was saying essentially what you're now saying in rebuttal. Read it again!

    21. Re:A question for the bio geeks.. by Kurofuneparry · · Score: 1

      Ah, pardon the misunderstanding

      --
      ...... and idiots rule the world....
    22. Re:A question for the bio geeks.. by Anonymous Coward · · Score: 0

      Hmm ... that will work as long as you don't chew. Skoal!

    23. Re:A question for the bio geeks.. by Biotech_is_Godzilla · · Score: 1

      No worries, sir, you are a gentleman and a scholar, and I have massive respect for you for admitting error when the main problem here may well be me misinterpreting your mention of breeding as being about sex when you quite possibly meant somatic cell proliferation and I got the wrong end of the stick. I'd give you some references for my above claims, but sadly I have only heard them through my PhD supervisors, who I trust to be right (or at least supported by the opinion of someone someone they approve of) as they've worked in the field of DNA repair for 15+ years; and a review or two. Somatic cells do survive and continue to perform their normal role with fairly massive damage to their genomes, but whether they're then capable of being converted to viable stem cells or not is a gap in my knowledge... Probably a gap in the literature too. People look at the teratomas formed by stemming-gone-wrong and theorise about how they arise, but I don't think they actually know (i.e. have confirmed) the reasons. It would be an interesting question to answer, and pretty easy to do, potentially.

  5. immortality by Anonymous Coward · · Score: 3, Interesting

    every advancement in medicine, and health is another step towards immortality.
    Only problem is, you can replace everything in the body except the brain.

    generations from now people will be living over 200 years of age, I can see new problems arising.
    Over population is a problem and the average lifespan is under 70.

    I see a future of hybrid human technology species

    1. Re:immortality by Anonymous Coward · · Score: 5, Insightful

      Over population is a problem ...

      Overpopulation is not a problem. That is a myth that has been perpetuated since the latter half of the 18th century. Do the math.

      Only problem is, you can replace everything in the body except the brain.

      Perhaps even the brain... someday. There's nothing inherently mystical or supernatural about the brain that must make it impossible to transfer knowledge and identity from one to the other. We just don't know how... yet.

      I see a future of hybrid human technology species

      Without a doubt. I anticipate that it will start becoming a regular occurrence for people to augment their physical and even mental abilities with machines well before the end of this century.

    2. Re:immortality by EnsilZah · · Score: 1

      On the subject of overpopulation, there's also this recent TED talk:
      http://www.ted.com/talks/hans_rosling_religions_and_babies.html

    3. Re:immortality by FrootLoops · · Score: 1

      Indeed, many humans currently have technology implanted in them. My dad has both an internal cardioverter-defibrillator (a pacemaker that also shocks his heart out of dangerous rhythms) and a ventricular assist device (a battery-powered heart pump). He would be long dead without the shocker, and he would probably be dead without the pump. This likely isn't what you had in mind, but it's something real.

    4. Re:immortality by interkin3tic · · Score: 1

      But the current average lifespan is not reflective of future medical breakthroughs. If we make replacement hearts, livers, and kidneys in the next 10 years from induced pluripotent stem cells, that will really boost that number up quite significantly. Possibly it will extend our lives until we learn how to replace neurons with circuitry. Maybe we'll live that long naturally anyway.

      The far future is wide open with possibilities, who is to say we can't achieve virtual immortality in our lifetimes? I mean, I'm not betting on it, but ruling it out entirely?

    5. Re:immortality by Anonymous Coward · · Score: 0

      "Overpopulation is not a problem. That is a myth that has been perpetuated since the latter half of the 18th century. Do the math."

      "Brought to you by.
      http://www.overpopulationisamyth.com/"

      "Copyright © 2010â"2011 Population Research Institute. All rights reserved. "

      http://pop.org/about/who-we-are-800

      "Our growing, global network of pro-life groups spans over 30 countries."

      "pro-life" ....

    6. Re:immortality by Exrio · · Score: 1

      Mind conservation: THAT'S THE FUCKING PROBLEM. We need new minds - blank brains. Imagine having to live with old and rich people who has the MAFIAA mindset for indefitine time... You know they're the ones who have enough paper in their wallets to pay the bill for life extension treatments the day they're available, and while newer generations may seem fresh now I'm sure they will start presenting similar problems 60 years on. We really should solve the social problems of the world before we start talking about solving the bioligical ones. All this stuff is like throwing hardware at the problem without ever bothering to look at the (sorry state of the) software. Sometimes it infuriates me.

  6. Where's George Bush? by Anonymous Coward · · Score: 0, Troll

    We need a republican hero to block this effort!

    1. Re:Where's George Bush? by Spiked_Three · · Score: 4, Funny

      they cloned him as Mitt Romney and he is on the way, patience.

      --
      slashdot troll = you make a compelling argument I do not like the implications of.
    2. Re:Where's George Bush? by LordLucless · · Score: 1

      I was wondering how long it would take some troll to raise the utterly irrelevant controversy over embryonic stem cells.

      --
      Just because you're paranoid doesn't mean there isn't an invisible demon about to eat your face
    3. Re:Where's George Bush? by Anonymous Coward · · Score: 0

      We need a republican hero to block this effort!

      How would he block research in Israel is beyond me...

    4. Re:Where's George Bush? by Anonymous Coward · · Score: 0

      AC Fail.

      More likely a Democrat would because it's doesn't involve fetal stem cells.

    5. Re:Where's George Bush? by Cute+and+Cuddly · · Score: 1

      Bush is being protected by PETA. So much making monkey faces, they think he is one!

    6. Re:Where's George Bush? by zotz · · Score: 1

      "I don't understand why people who like command line environments don't get punch card machines for the best experience."

      ~;-)

      If you have used both, surely you can at least hazard a guess...

      --
      FreeMusicPush If you want to see more Free Music made, listen to Free
    7. Re:Where's George Bush? by INowRegretThesePosts · · Score: 2

      We need a republican hero to block this effort!

      No one opposes research involving stem cells that does not kill human embryos.

      By resorting to straw man, you just show you have no real argument.

    8. Re:Where's George Bush? by Spiked_Three · · Score: 1

      I have, and not really. Compared to a GUI, they are the same.

      --
      slashdot troll = you make a compelling argument I do not like the implications of.
  7. Re:WHAT WHITE PEOPLE ARE HIDING! by geekoid · · Score: 1

    Damn it, he found us out. ok White ISP guy, give use his address so he can have a heart attack tonight.

    " white people cannot reproduce themselves efficiently like normal black people"
    there is no subspecies of human being.

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
  8. Re:WHAT WHITE PEOPLE ARE HIDING! by Anonymous Coward · · Score: 0

    All the joy of riding a public bus with a crazy on board, right here in a post on slashdot...

  9. Ah yes, the human heart... by sootman · · Score: 1

    ... also known as "the love muscle."

    --
    Dear Slashdot: next time you want to mess with the site, add a rich-text editor for comments.
  10. Re:WHAT WHITE PEOPLE ARE HIDING! by Samantha+Wright · · Score: 1

    I weep at the thought of how much server disk space goes into storing these half-hearted spam messages. Slashdot clearly needs some sort of r9k solution.

    --
    Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
  11. Re:WHAT WHITE PEOPLE ARE HIDING! by slashchuck · · Score: 3, Funny

    Slashdot should reduce the font size of the Troll/Flamebait postings. It will cut down on the disk space used.

    --
    $sig not found
  12. The Tin Man rejoices by c4tp · · Score: 1

    The Tin Woodman rejoices

    1. Re:The Tin Man rejoices by Anonymous Coward · · Score: 0

      I'm so happy for him! We'll just take a few of his skin cells and... oh crap.

  13. Soon enough? by __aaltlg1547 · · Score: 1

    That's really impressive, but is it medically useful in the instance they mention in the summary? If you have advanced heart failure, aren't you in danger of your heart just topping REAL SOON NOW? Can they use the stem cells to repair your heart before you die? It would be more credible to treat people who have had a heart attack and some damage but aren't yet in advanced heart failure.

    1. Re:Soon enough? by Genda · · Score: 1

      In fact, there is recent work described in this months Discover about using proteins produced by pythons (and no not the language) to renew and strengthen damages hearts.

    2. Re:Soon enough? by Anonymous Coward · · Score: 1

      Failure is the danger of a tear in the muscle or a valve. A tear is usually what cascades into death. We've gotten good at patching, but usually that requires heart tissue. From your heart. Whoops. Being able to patch from cadavers lasts not too long (at best, a couple years, at worst it fails immediately on restart). Creating native (genetically matching) and living tissue, you go from potential failure in the forseeable future to potential failure in another area before the patch fails.

  14. Hair cells please by ChrisMaple · · Score: 1

    I'd like not to have to wear a hat to keep my scalp from being sunburned.

    --
    Contribute to civilization: ari.aynrand.org/donate
    1. Re:Hair cells please by alantus · · Score: 1

      I second that! Is there any research going on to grow hair???
      I know being bald is not as bad as having a heart problem, but it is definitely something that people need and would make a lot of money in return.

  15. Re:WHAT WHITE PEOPLE ARE HIDING! by Genda · · Score: 1

    Do they make a 0.0001 point font? Screw the disk space, He's wasting my life space... I want that post covered by a single period.

  16. Clumsy me, broke the bottle by Anonymous Coward · · Score: 0

    Now it's all over my hands. Dang.

    thump thump

  17. Re:WHAT WHITE PEOPLE ARE HIDING! by Anonymous Coward · · Score: 0

    Yea, we allready know this! London rules the world, all the royals control the major corporations, royals killed Kennedy, white are killing all the africans in africa, the royals plan on inslaving every one, yet its to late too do any thing about it know, so just eat the poison and enjoy.

  18. Pics or it didn't happen by Anonymous Coward · · Score: 0

    Pics or it didn't happen

  19. All skin cells? by Czubaka · · Score: 0

    Now image, a mad scientist with a skin cells changing blaster hiding in the dark corner, waiting to change all your skin into little beating hearts. Aaaaarrrgh!!!

  20. T.I.I.T. by Anonymous Coward · · Score: 0

    With abbreviation like that, i bet i know which tissue they will be working on next...

  21. Young except for the telomeres...? by rgbatduke · · Score: 1

    Actually, this is in part a question. Although I could probably read TFA to find out (maybe it answers this) but one issue with rejuvenation is rewinding the telomeres (so to speak) so they aren't too long (cancer) and aren't too short (premature cell death). There are a lot of clocks in cells and tissue, and my general question is: Does skin -> stem -> tissue cell reset them all so that the new tissue really is "like that of a newborn" or whatever with the original DNA complement?

    Not good to be able to build the heart of a Chicken Little (props for ref:-) that simply up and dies on you, or gets cancer, for other reasons.

    rgb

    --
    Even when the experts all agree, they may well be mistaken. --- Bertrand Russell.
    1. Re:Young except for the telomeres...? by Anonymous Coward · · Score: 0

      Going to stem state activates telomerase which is why stem cells can be reproduced indefinitely. However telomerase gets knocked down when you go from stem to heart cell.

    2. Re:Young except for the telomeres...? by Anonymous Coward · · Score: 0

      Not good to be able to build the heart of a Chicken Little (props for ref:-) that simply up and dies on you

      OK, so I remembered reading that but forgot where, so I searched for the original story and found that it was based on a real chicken heart.

  22. Re:WHAT WHITE PEOPLE ARE HIDING! by Anonymous Coward · · Score: 0

    tl;dr.

  23. Re:WHAT WHITE PEOPLE ARE HIDING! by Anonymous Coward · · Score: 0

    If being enslaved by the Royals means I get to bang Pippa, then I for one welcome our Royal overlords. I wonder if she likes hot grits?

  24. Re:WHAT WHITE PEOPLE ARE HIDING! by Anonymous Coward · · Score: 0

    Someone seriously found this funny? /dismayed

  25. Just the left side by Dareth · · Score: 1

    I just want the left side of my body replaced with technology. Then I would finally be "All Right".

    --

    I only look human.
    My mother is a halfling and my dad is an ogre, so that makes me an Ogreling
  26. Would they still need big trucks then? by Dareth · · Score: 1

    Would they still need big trucks then? You know, to compensate.

    --

    I only look human.
    My mother is a halfling and my dad is an ogre, so that makes me an Ogreling
  27. stem cell researcher here. by Anonymous Coward · · Score: 0

    Cancer is actually a concern with any stem-like cells, because they all have telomerase activity, and frequently have active myc or other proto-oncogenes that allow cells to divide indefinitely. (these authors only used Oct, Sox and Klf - most groups also use the oncogene myc to reprogram cells for that exact reason)
    However, its actually really hard to get cancer: if you inject one cancer cell into the body (or even up to a few million) you will probably still not get a tumor. Likewise, when you go from stem back to heart cell, the cells slow down their division rate and generally stop acting cancer-like.
    Your concern that skin cells from aged patients may be abnormal genetically to start is a minor concern, and can be checked

  28. Insulin Applications? by LifesABeach · · Score: 1

    Could the same method be applied to the Pancreas?

  29. It OK, we harvested the skin cells from... by tlambert · · Score: 1

    ...your parents basement.

    -- Terry

  30. Just One Question... by Whammo_777 · · Score: 1

    So there's still hope for Dick Cheney?