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ADHD Drugs Aren't Doing What You Think, Scientists Warn (inverse.com)

An anonymous reader quotes a report from Inverse: The study authors Lisa Weyandt, Ph.D., a professor of psychology at the University of Rhode Island, and Tara White, Ph.D., an assistant professor of Behavioral and Social Sciences at Brown University, started out investigating the effects of ADHD medications in students that actually have a diagnosable attention deficit disorder. They showed that in these students, there is decreased activity in the areas of the brain controlling "executive functions," which can make it hard for them to stay organized or focused. But because both authors work with college students, they soon became more interested in the misuse of Adderall. In students whose brains aren't affected by ADHD, does Adderall act as a supercharger? Does it make those areas fly into overdrive and unlock otherwise untapped intellectual ability, as all pill-popping students hope?

Weyant and White's double-blind, placebo-controlled study on 13 college students was a small sample, they admit, but their experiment had a rigorous study design. Neither the students nor the researchers knew who was getting Adderall and who was getting placebo sugar pill. The six tests evaluated different aspects of cognition, like working memory, reading ability and reaction time. While students on Adderall did make fewer errors on a reaction time test, it actually worsened working memory, as shown by a decline in performance on a task where they had to repeat sequences of numbers. In short, Adderall improved focus and attention -- but it didn't actually make anyone smarter.
The research has been published in the journal Pharmacy.

183 comments

  1. "Didn't make anyone smarter..." by HotNeedleOfInquiry · · Score: 4, Insightful

    " Adderall improved focus and attention -- but it didn't actually make anyone smarter." Presumably, you are reasonably smarter already, being accepted in college. So the real benefit is focus and attention, not "smarter".

    --
    "Eve of Destruction", it's not just for old hippies anymore...
    1. Re:"Didn't make anyone smarter..." by jordanjay29 · · Score: 3, Insightful

      Right. I never heard of anyone taking them to make themselves smarter. Just to get stuff done, like studying or papers/projects. I'd be interested to see a study done on knowledge retention for learning done on adderall vs without.

    2. Re:"Didn't make anyone smarter..." by Plus1Entropy · · Score: 3, Funny

      An alternative headline could be: "ADHD Drugs Are Doing Exactly What They Are Prescribed To Do, Scientists Confirm".

      --
      Only crack the nuts that crack. You don't put the ones that don't crack in the sack.
    3. Re:"Didn't make anyone smarter..." by alvinrod · · Score: 3, Interesting

      I think that a lot of students are probably using it as a crutch. There are people who legitimately need these substances to function, but there are too many people who are abusing them at the expense of learning some discipline and focus. Yes, it sucks to have to sit down to do a term paper, but really what you should have been doing is spending small amounts of time over the semester working on it instead of putting it all off until the last possible minute.

      Whatever you exercise, you will make stronger. Don't assume that self-control and willpower are any different. Of course you can exercise your vices and bad habits just as easily.

    4. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      " Adderall improved focus and attention -- but it didn't actually make anyone smarter."

      The authority hates smart slaves.

      We are slaves.

      We are supposed to be stupid.

    5. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      College has nothing to do with being smarter. Unless you're pursuing a hard science, it's the worst 'investment' you can make.

      In reaction to the article, well, no shit.The free ride has yet to be discovered.

    6. Re:"Didn't make anyone smarter..." by Narcocide · · Score: 1

      I just want to know how it stacks up against caffeine for the same use cases.

    7. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      I just want to know how it stacks up against caffeine for the same use cases.

      I can't speak for muggles, but as someone with ADHD (adult), caffeine does fuck all. Modafinil is next, doing approximately nothing, along with the various old and safe nootropics I've tried. On the other hand, the prescribed drugs work.

      One unexpected thing I've found is that a cocktail of ritalin (normal 75-100% of the usual does) and green tea (about a liter) has a better effect than ritalin alone, if I'm not sleepy. (It seems as though the caffeine gets "used up" if it has to keep me alert and has no remaining effect on my attention.) I don't know whether the effect continues to work over time, because it's such a pain to drink a liter of tea that I almost never do it.

      (Obviously the above may simply be due to l-theanine and caffeine, which IS a well documented nootropic combination, but for some reason I haven't observed a positive effect when taking those supplements.)

    8. Re:"Didn't make anyone smarter..." by Ferocitus · · Score: 3, Interesting

      I find that 12 to 16 cups of (instant) coffee per day + 30mg dexedrine works for my adult ADHD. Small amounts of cannabis (1/2 a cone every 2-3 hours) as well is even better. Large amounts of weed, while nice, doesn't help my maths research.

      The benefits attributed to l-theanine are mostly bullshit.

      --
      USB, USB, USB!
    9. Re:"Didn't make anyone smarter..." by David_Hart · · Score: 1

      Right. I never heard of anyone taking them to make themselves smarter. Just to get stuff done, like studying or papers/projects. I'd be interested to see a study done on knowledge retention for learning done on adderall vs without.

      Exactly. There wasn't any mention of testing to see if long-term memory retention is affected. After all, I thought that students took adderall to study for tests.

    10. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Hello,
      Thanks for sharing your experience. My son uses Concerta drug for diagnosed ADHD, and really helps him to get focussed and self-controlled. During summer we remove medication since he din't gi to school and there is a truly difference. One of the big ones is the way he eats, during school time he seems to have lost appetite. Out of medication time he is usually hunger.
      Maybe some of the teenagers misuse this medication to Âbe in dietÂ.

    11. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      If youâ(TM)re a hard scientist, give us some numbers. Youâ(TM)d see that students who go to college make way more money during their careers than those that donâ(TM)t.

      If it comes down to dollars and cents, a therapist or computer âoescientistâ makes better money than a chemist. Hard science generally does not pay as well as soft.

    12. Re: "Didn't make anyone smarter..." by Khyber · · Score: 0

      No fucking duh, most any teenager knows stimulants work well as weight cutters. The Crystal Meth diet has been known for over 20 years.

      --
      Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
    13. Re: "Didn't make anyone smarter..." by reanjr · · Score: 2

      Did you miss the part where it says, "can make it hard for them to stay organized or focused"?

    14. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 1

      I have found that any head-ache or common cold pill made me perform better in examinations. I don't know which ones are best but a combination common cold antihistamine plus pain reliever would boost my abilities very much and I would do 10 to 20% better in the exam.

      To improve studying, any head-ache pill would work wonders - even the good old aspirin. Coffee of course is probably the most common performance booster, but coffee plus aspirin, or coffee plus half an antihistamine is a lot better. So there is actually is a lot to be said for a little brain medication once in a while and it is something that should be researched better than these 'personal experiences'.

    15. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 1

      Coffee makes the world go round, but coffee plus a head-ache pill, really gets me going and enables me to do new things that nobody else thought of, or could get to work before. Note that I am an aerospace engineer and really need my smarts about me. I have found that simple meds really does change me from merely being above average, to a superior intellect for a few hours.

      The fuckup is in the morning after, but I recover by swimming 1000 meters almost every night to stay above average fit also - 5 to 6 km a week. I've been doing this for 40 years and earn half a million dollars a year, so it works and I am old and more healthy than most.

    16. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 2, Interesting

      I find that 12 to 16 cups of (instant) coffee per day + 30mg dexedrine works for my adult ADHD.

      Do you know whether that's safe? My doctor discouraged me from drinking more than 1-2 cups of coffee per day when taking a stimulant, though he admitted it's an educated guess rather than something specific from a study. (Coffee and/or ADHD meds may cease to be a heart stimulant after you get acclimated.)

    17. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Why donâ(TM)t you just brew your tea stronger? 4 bags in 250 ml, for example?

    18. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Wrong question.
      Does it improve exam performance? Yes or No.
      Does it help people who are not good reading on technical detail (study) cram stuff that they would normally gloss over.
      The boots on ground say hell yes - and they need to if they have to pay back student loans.
      However I have seen takers forget the stuff quicky after the exam. Cost benefit for expensive schools and uni's is another easy decision when 70% of your classmates are.

    19. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Head-ache pill? You know a lot of them have caffeine in them so you may just be doubling down on caffeine.

    20. Re:"Didn't make anyone smarter..." by Ferocitus · · Score: 1

      I'm over 60, I like stims and I don't care if they're safe or not. I don't live my life like a timorous flounder on the bottom of the sea, forever worried that I'll get a spear in the back of the neck.

      --
      USB, USB, USB!
    21. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Stupidity does not age!

    22. Re:"Didn't make anyone smarter..." by reboot246 · · Score: 1

      If you really were smart, you wouldn't take the drug.

      Oh, just being accepted at a college doesn't mean you're smart. A LOT of them have lower standards nowadays. There are college students who can't read at more than a 6th grade level.

    23. Re:"Didn't make anyone smarter..." by Antique+Geekmeister · · Score: 0

      Adderall, while increasingly popular, has long been familiar among college students. It's a medically pure variant of methamphetamine. Looking into the older tests on methamphetamine and the consequences of its long term use are not promising for the current popularity of the drug.

    24. Re:"Didn't make anyone smarter..." by Ferocitus · · Score: 1

      Pffft. You and your band of geniuses are welcome to do what you like with the world! I like my 28 hour days.

      --
      USB, USB, USB!
    25. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Caffeine is great at keeping the caffeine withdrawal headaches away. For everything else, there's dextroamphetamine. I'm currently able to operate on a bad night's sleep (less than two hours of deep sleep, then two or so more of intermittent sleep) without feeling like my head is a buzzing hollow.

    26. Re:"Didn't make anyone smarter..." by Rockoon · · Score: 1

      I raise issue with calling it a "double-blind study" since clearly those that got meth instead of sugar figured it out on the first dose. There are some thing you cant play make believe about. You may be able to trick someone into thinking they got it when they didnt, but there is no way to do the opposite.

      --
      "His name was James Damore."
    27. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Sounds like you need to try some coke, then you'll function like tiger blood.

      Duh, winning!

    28. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Isn't that ok, though? I thought Russia was our good friend and ally, or were they our enemy up until the time Trump was elected? Uranium One! Uranium One!

      I wish you bipolar constituents would make up your minds...

    29. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      https://www.instapaper.com/

    30. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Yeah? Guess who's NOT in prison and who hasn't even been indicted on any charges by the government? Hillary Clinton! Guess what else? The US Government hasn't executed anyone for treason since the 1960's which was around the same time they stopped using hanging as the method of execution.

      But hey, good job voting for the "lessor of two evils" and let me be the first to say, "HAHAHAHAHAHAHHAHAH! YOU FUCKING TOOL!"

    31. Re:"Didn't make anyone smarter..." by Ol+Olsoc · · Score: 3, Informative

      Exactly. There wasn't any mention of testing to see if long-term memory retention is affected. After all, I thought that students took adderall to study for tests.

      One could surmise that if working memory is affected, long term memory will be affected as well.

      It is interesting that this recent test found different results regarding working memory than a 2015 test did. https://en.wikipedia.org/wiki/...

      Granted, the Wikipedia entry reads more like a drug company propaganda piece, taking an amphetamine and elevating it to miracle drug status. Probably to make parents feel good about drugging their young boys to keep them in line.

      Which would be contradictory to the rest of the world's not so good experiences with amphetamine drugs.

      Back in the day, in college, we had access to various amphetamines. It always followed a predictable course. Take them, cram all night, take the test. Crash. The trick was to not crash before taking the test.

      Homie didn't play that. I tried cramming a few times, because it was what you were supposed to do. It really doesn't work. And since I don't sleep much anyway, there was no need for speed.

      --
      The shepherds did so well protecting the flock that the sheep no longer believed that wolves existed.
    32. Re:"Didn't make anyone smarter..." by starless · · Score: 4, Funny

      I raise issue with calling it a "double-blind study" since clearly those that got meth instead of sugar figured it out on the first dose. There are some thing you cant play make believe about. You may be able to trick someone into thinking they got it when they didnt, but there is no way to do the opposite.

      Which, of course, calls for the relevant XKCD comic...
      https://xkcd.com/1462/

    33. Re: "Didn't make anyone smarter..." by CoolDiscoRex · · Score: 1

      They better make more, since they start life with far more debt. Now that every barista in town has a college degree, however, they don't have the value they used to have. Companies have kind of caught on to the notion that degrees are now commodities, and there seems to be a renewed interest in the self-taught, as they often bring to the table a stronger work ethic since they had to work harder to get where they are, without the crutch of the degree. I mean, we all know a few handfuls of college-educated co-workers who try and skate by, but rare is the self-taught person who does the same. They had to work twice as hard just to get in the same room, and it usually shows. Not saying that college degrees aren't great things to have, but as an investment, they're getting less valuable. That's what happens when supply rises. Now, everyone is supposed to have a degree. Once upon a time, it was okay to learn a trade. College is a business like any other, and people with reasonably affluent parents are virtual assured a degree. Perhaps in Art History, but it's a degree nonetheless. Having a college degree is not what it used to be.

    34. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Adderall's only legitimate medical use is in patients with advanced Parkinson's disease because it causes Parkinson's disease.

      This has been reliable established decades ago beyond just a link to an actual mechanism.

      Ritalin though is reasonably safe when taken in therapeutic doses and overseen by a doctor for actual ADHD.

    35. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 1

      Dexosyn is meth adderall is a mix of amphetamine salts stop spreading lies

    36. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      I would do exactly the same thing, in your shoes.

    37. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 1

      I raise issue with you calling it Meth. Methamphetamine is, on average, 100x more potent than Amphetamine salt combos, dextroamphetamine, or any other Amphetamine-based prescription drug.

      So if that's the equivalence you're drawing, I hope you've never driven after having a beer, because by your logic, it's the same as you chugging a bottle of Jack Daniels.

    38. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Even better, people who worked to put themselves through college w/o student debt or mom/dad $$. You get the best of both.

    39. Re:"Didn't make anyone smarter..." by Trickster+Paean · · Score: 4, Informative

      That's completely incorrect. Don't spread misinformation.

      Adderall, and its generic equivalents, are a combination of 25% levoamphetamine and 75% dextroamphetamine salts. They both have the chemical formula C9H13N.

      Methamphetamine is a different drug entirely. In its medical form, it is generally sold as dextromethamphetamine hydrochloride, or under the trade name Desoxyn. Its chemical formula is C10H15N.

      Both are approved for the treatment of ADHD in the US, but Adderall is much more likely to be prescribed. Under long-term medical use at therapeutic doses, addition is unlikely to occur with Adderall. While methamphetamine is approved for the treatment of ADHD, it is seldom prescribed due to the risks of recreational abuse and addiction associated with it. That said it is a safe and effective treatment for some people when other treatments fail.

      Abuse of these drugs is another matter entirely.

    40. Re:"Didn't make anyone smarter..." by Trickster+Paean · · Score: 2

      Looking at the study itself, the students were given a 30mg dose of Adderall. Therapeutic doses start at 5 mg.
      So it doesn't surprise me that the side effects from a 30 mg dose overwhelmed any possible cognitive improvements.

      The studies cited that found cognitive improvements also note that there is a dose response-curve, where up to a certain dosage, you see improvements in sustained attention and working memory, and past that working memory takes a dive while sustained attention continues to improve. Until it too begins to decrease.

      These aren't wonder drugs. They're drugs. They're substances that have physiological effects on the body. Doses make a difference.

    41. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      I hear meth is cool if your ignore all the dangers.

    42. Re:"Didn't make anyone smarter..." by Billly+Gates · · Score: 1

      No you can't. I have ADHD bad. I can not just simple do something and stay focused as easily as a normal person. It just won't happen.

      Yes Adderal helps greatly. Unfortunately, it is a nasty bugger that is addictive and got me fired from a previous job as I blew my lid and almost assaulted a coworker as one of the side effects are violent tendancies and my patience grows thin.

      FYI I am not a violent person like some men are but I can't take that shit unfortunately and do not want to get high or feel like I am running 1,000 mph. I just want to be able to focus and have the day go by quick and be focus and be disciplined enough for life improvements when I am not at work

    43. Re:"Didn't make anyone smarter..." by Billly+Gates · · Score: 1

      It is a complete other level. The closest I can say is it is like crack. You feel an enormous high ephoria and a rush of energy.

      I realized it was dangerous when I took and was cautious to take a half child's dose as I do not want to get high or addicted but just be able to focus and get on through my work day quickly and have generally life improvements with focus on what I know I need to do.

      Caffeine wakes you up a little and drives anxiety if you are stressed but it is not the same.

    44. Re:"Didn't make anyone smarter..." by JMJimmy · · Score: 1

      As someone with ADHD and been on most of the meds: DUH!

      Yes, the meds help focus. This is particularly helpful for hyperactive symptoms where, as they describe it, "a thousand thoughts happen at once" - it's very helpful to focus amidst all that noise. It also helps to speed up things very slightly to deal with the slower than normal pathways the ADHD brain uses.

      It doesn't help working memory, one of the worst aspects, nor does it help impulse control. Memory might be improved by Alzheimer medication but ultimately medications are an aid, not a cure.

    45. Re:"Didn't make anyone smarter..." by azcoyote · · Score: 2

      Under long-term medical use at therapeutic doses, addition is unlikely to occur with Adderall

      So it only makes you smarter with subtraction? How about trigonometry?

      Seriously though, I wonder what "addiction" is supposed to mean when it is said that addiction is unlikely to occur with Adderall. I can buy that meth might be more chemically addictive than Adderall, but Adderall is definitely habit-forming. The problem with the word "addiction" is that in common parlance it can cover many different situations of habit with completely different causes. Perhaps Adderall does not make someone dependent the way that nicotine does, but it is easy to be in a situation where making the decision to take Adderall or not to take the med is not a purely rational, level-headed choice.

      --
      Incipiamus, fratres, servire Domino Deo, quia hucusque vix vel parum in nullo profecimus.
    46. Re:"Didn't make anyone smarter..." by Scarletdown · · Score: 1

      But without ADHD meds, how will Space Shire Seven become a reality?

      Ah well, got access to better stuff legally. Going to try Strawberry Fields tomorrow. Normally $100 an ounce, on sale at $80, and if I calculated correctly, after military discount (retired) should be $72.

      --
      This space unintentionally left blank.
    47. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      I have ADD and take Adderall. I say that it doesn't help me to pay attention, so much as it gives me a larger store of attention from which I can pay. It's like caffeine, but without the jittery buzz.

    48. Re:"Didn't make anyone smarter..." by Darinbob · · Score: 1

      Don't forget, there is a lot of over-diagnosis of ADHD who may be getting the medicine because it's prescribed even though they don't need it.

    49. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      But seeing as Adderall helps with executive decisions, you could argue that you become "smarter" simply by being able to use your brain properly. Smarter maybe just as smart as everyone else without ADD.

    50. Re:"Didn't make anyone smarter..." by Trickster+Paean · · Score: 1

      Ha ha ha, I made a typo.

      Seriously, if we are talking about addiction, that is usually a combination of both physical dependence and psychological dependence.
      Adderall does not cause physical dependence, unlike drugs like nicotine or opioids or even alcohol. What does happen is psychological dependence and changes to the brain's dopamine system due to abuse. If amphetamine is abused, drug tolerance develops rapidly, and abusers have to take increasingly larger doses to get high. This can cause long-term changes in the brain's dopamine levels, often causing a withdrawal syndrome.

      But this is not what happens when used long-term at therapeutic doses. There's little evidence to suggest that similar long-term changes occur in the brain when used at therapeutic levels. Some people will form psychological dependences on it anyway. But even a psychological dependence does not imply the problems of addiction.

      Adderall is addictive, and those at biggest risk are new users and people abusing it recreationally. But if someone is taking it long-term, at therapeutic doses, they are unlikely to exhibit the classic hallmarks of addiction, such as impaired control over the substance, preoccupation with the substance, and continued use despite negative consequences.

      Whether to take any medication is never a purely rational, level-headed choice. It is a combination of both the motivations and emotions that we have, and the rational calculus that forms part of our decision making.

    51. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      That last treason conviction was 1952 for WW2 crimes. Not even the Rosenbergs where tried for treason.

    52. Re:"Didn't make anyone smarter..." by Antique+Geekmeister · · Score: 0

      > That's completely incorrect. Don't spread misinformation.

      I've not done so. As I stated, it's a medically pure _variant_ of methamphetamine. They're very similar, chemically and clinically. And yes: mmethamphetamine has an extra methyl group that increases its potency, hence its name. In use, this is mostly made up for by the higher quality of medical grade Adderall compared to street meth. For juveniles and college age users, much of the supply is "diverted" from prescriptions.

      > Under long-term medical use at therapeutic doses

      I'm afraid that many patients, and physicians, cannot be relied on to follow clinical guidelines. And the tendency to misprescribe, to resell, and to share, Adderall is high.

      > Abuse of these drugs is another matter entirely.

      Neglecting the abuse of these variants, their addictive nature, and the results of their long-term use on performance and on quality of life is to ignore vital clinical data relevant to tests on Adderall itself.

    53. Re:"Didn't make anyone smarter..." by Antique+Geekmeister · · Score: 1

      > Adderall does not cause physical dependence, unlike drugs like nicotine or opioids or even alcohol. What does happen is psychological dependence and changes to the brain's dopamine system due to abuse

      Addiction due to abuse is still physical addiction. Even used clinically, patients are weaned off of the drug when they stop using it. The physical addiction is one of the reasons not to discontinue it "cold turkey".

    54. Re: "Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      Taking too low of an amphetamine dose can cause the opposite to happen where it feels like you have taken a huge dose, makes you hyper sensitive to it in the future, and can cause other unwanted side effects like the jitters/shakes. I believe it is called amphetamine reverse tolerance. If you took half of a child's dose, this may have happened to you.

    55. Re:"Didn't make anyone smarter..." by volmtech · · Score: 1

      At 46 wife was part of a study for a new ADHD drug. Whatever she took did not help but she was then given a year's prescription for another drug, Vivance. It is an amphetamine but acts differently. She became a new woman. She had barely graduated high school and had only worked as a waitress and store clerk.

      I am disabled and we needed more income so she went school to become a nurse. After I showed her how to do web searches on her new laptop she became a super student. She graduated top of her class. She also had enough energy to spend "quality" time with me. She started going by her second name instead of her first. Sonya is a tiger! She had a great three years, unfortunately it costs $360 a month so now she takes a cheap generic amphetamine. Instead of working 12 hours a pill only works for four and then they only keep her awake. Sonya is mostly gone and scatter brained Michelle has shown back up. She recently started back crafting, her new project is smashing mirrors and gluing the pieces to the hallway ceiling for a mosaic.

    56. Re:"Didn't make anyone smarter..." by Peter+P+Peters · · Score: 1

      Adderall, while increasingly popular, has long been familiar among college students. It's a medically pure variant of methamphetamine.

      You are confusing amphetamine with methamphetamine.
      They are different things....

    57. Re:"Didn't make anyone smarter..." by Antique+Geekmeister · · Score: 1

      Adderall is missing a methyl group that methamphetamine has. Perhaps I should have been more cautious with my language, and called it "chemically related" instead of a "variant". I'm also afraid that their medical effects are more similar than many wish to admit, resulting in their misuse.

    58. Re:"Didn't make anyone smarter..." by arglebargle_xiv · · Score: 1

      You'd think people would have become wary of the stuff since it was sold as Pervitin eighty years ago. Back then the Panzerschokolade was regarded as a miracle drug as well, until the side-effects started to show up...

    59. Re:"Didn't make anyone smarter..." by MonteCarloMethod · · Score: 1

      It isn't much help with trig either. All of the taylor series expansions of the basic trig functions contain addition. There is of course the edge case of arcsin and arctan for which the expansions are purely subtractive.

    60. Re:"Didn't make anyone smarter..." by Anonymous Coward · · Score: 0

      So swimming 1000 m is the prevention for the coffee and tylenol hangover? I just pray and it usually helps me with that...

    61. Re:"Didn't make anyone smarter..." by Peter+P+Peters · · Score: 1

      I'm also afraid that their medical effects are more similar than many wish to admit, resulting in their misuse.

      Of course you have a citation for this? I only ask because I just watched a Netflix doco on recreational use of Adderall (and Ritalin) and the experts they interviewed said the two are like chalk and cheese. This doco matched my own personal experience where I've seen Meth users go completely off the rails, resulting in heavy addiction and violent crime while Amphetamine and Methylphenidate users seem to behave like regular people, just with more periodic boosts in energy and happiness.

    62. Re:"Didn't make anyone smarter..." by Peter+P+Peters · · Score: 1
  2. Pretty small sample size by Anonymous Coward · · Score: 0

    So these results are hard to generalize.

    1. Re:Pretty small sample size by Anonymous Coward · · Score: 0

      Correct. A sample size of 13 is utterly worthless statistically. No useful information can be had from such an experiment.

    2. Re:Pretty small sample size by Anonymous Coward · · Score: 1

      What will really bust your noodle later is a large majority of behavior modification/investigation is done ostensibly with college students. These same students have to take part in research study as part of a required course's requirements. This is not a great source of random sampling.

    3. Re:Pretty small sample size by Anonymous Coward · · Score: 0

      They should have performed fMRI on the volunteer students and compared to the reference of reduced brain activity.

    4. Re: Pretty small sample size by Anonymous Coward · · Score: 0

      Red light, green light, red light, green light, red light, green light, they like, we like FAST CARS

    5. Re:Pretty small sample size by Whibla · · Score: 5, Interesting

      Correct. A sample size of 13 is utterly worthless statistically. No useful information can be had from such an experiment.

      Incorrect. A sample size of 13 does give statistically significant results (for a fairly specific version of significant), and is, in fact, the smallest sample size to do so.

      It might never have occurred to you to wonder why legal trials have a judge and 12 people on a jury - making 13 people. Perhaps you should look into that: mathematically it's quite interesting.

    6. Re: Pretty small sample size by TheReaperD · · Score: 1

      I'm not sure which is more shocking. That you wrote that FUCKing post or that I read all of that FUCKing post!

      --
      "Be particularly skeptical when presented with evidence confirming what you already believe." -
    7. Re: Pretty small sample size by Ol+Olsoc · · Score: 1

      I'm not sure which is more shocking. That you wrote that FUCKing post or that I read all of that FUCKing post!

      Dooood! Cut that adderall dose in half man!

      --
      The shepherds did so well protecting the flock that the sheep no longer believed that wolves existed.
    8. Re:Pretty small sample size by Anonymous Coward · · Score: 1

      I'd assume the answer to why trials have 12 people on the jury is a matter of tradition. I seriously doubt anyone did the maths on it when it was decided. At some point someone decided 12 people was the right number for a jury and it stuck.

    9. Re:Pretty small sample size by azcoyote · · Score: 2

      Yep. A Google search revealed the historical reason that I had presumed from the beginning: it's because of the 12 tribes of Israel: https://www.insidescience.org/news/mathematics-jury-size

      More directly, it was connected to Jesus' twelve apostles, but the reason there were 12 apostles was because it was symbolic of the 12 tribes.

      --
      Incipiamus, fratres, servire Domino Deo, quia hucusque vix vel parum in nullo profecimus.
    10. Re:Pretty small sample size by Darinbob · · Score: 1

      13 students take a drug, 8 of them fall violently ill, then certainly it's stupid to dismiss that as statistically irrelevant.

    11. Re:Pretty small sample size by Whibla · · Score: 1

      To be fair that was a fairly interesting article, especially in the fact that it specifically mentions that jury sizes other than 12 have been discussed or tried.

      That being said, the historical 'fact' of "why today's juries tend to have 12 people is that the Welsh king Morgan of Gla-Morgan, who established jury trials in 725 A.D., decided upon the number" is sketchy at best (Glamorgan* not even being a dream by that date - this was almost certainly prior, even, to Glywysing being renamed Morgannwg because of the family name), and the rationale for it, attributed to Morgan is, as far as I can tell, a fantasy by the author if the article.

      However, my certitude as to the origins of the number or jurors was almost certainly a 'mis-speaking', or a verbal shortcut to the result, as my experience of the mathematics of jury size was covered in a university maths class back in the late 90's, but that certainly only accounts for why we continue to use 12 people, not why we started using 12 people. The hypothesis of Jesus and his disciples, or the 12 tribes of Israel, are perhaps as valid as the "Thing" which was introduced from, I believe, a non-Jewish, non-Christian culture.

      Either way, the primary point remains: 13 people is, for a small degree of error, a valid sample size. Clearly larger would be better, but to dismiss the study entirely, based purely on a misguided notion that a sample of 13 people is not 'significant', would be a mistake.

      *fwiw, which ain't much I'll grant, this (Glamorgan) is where I live...

  3. Ah yes, psychology, the bullshit pseudoscience by Anonymous Coward · · Score: 0

    Sorry, I'll believe real scientists. We all know psychologies aren't scientists. After all, they are responsible for the horrendous torture that came about with asylums and their "scientific" methods.

    I'd care if this from neuroscience; people who actually study the brain; not people who study emotions and then come up with some bullshit reason why x is y.

    1. Re:Ah yes, psychology, the bullshit pseudoscience by Anonymous Coward · · Score: 1

      I'll believe real scientists

      No matter their degree, as long as their conclusions match my biases.

    2. Re:Ah yes, psychology, the bullshit pseudoscience by Anonymous Coward · · Score: 0

      LOL like "doctors" didn't???

    3. Re: Ah yes, psychology, the bullshit pseudoscience by Anonymous Coward · · Score: 0

      We already knew that the pills don't really work in individuals that don't have ADHD, so this isn't really that surprising. Which is part of why ADDers can take the pills for years without getting hooked, but non-ADDers may develop a tolerance and subsequent addiction.

      Brains are very complicated and expecting something like these medications to have a similar affect on people with different wiring is questionable at best.

      The real problem here is that this is at best a preliminary study that should be used as the basis for something bigger.

    4. Re:Ah yes, psychology, the bullshit pseudoscience by omnichad · · Score: 1

      After all, they are responsible for the horrendous torture that came about with asylums and their "scientific" methods.

      Maybe dead ones. Might as well say the same for medical doctors and leeches or trepanning.

    5. Re:Ah yes, psychology, the bullshit pseudoscience by Megol · · Score: 1

      Is it you Tom Cruise?

  4. sample size of 13 by Anonymous Coward · · Score: 0

    Weyant and White's double-blind, placebo-controlled study on 13 college students was a small sample, they admit

    The quoted line is all you need to read to know there's nothing of value in the study.

    1. Re:sample size of 13 by Khyber · · Score: 0

      Spoken like a fool that has never been involved in actual research. You have to start somewhere, and usually small, to get others to try repeating your results on a larger scale. That's how most science works, now days.

      Signed,
      Former Horticultural Research Director

      --
      Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
    2. Re: sample size of 13 by Anonymous Coward · · Score: 0

      Is your job supposed to impress anyone?!? Haha, I see that title and think, âoeWow, I was making more money than this schmuck at my first job out of collegeâ. And I guarantee I know more about math/statistics.

      Sample size of 13 = not science.

    3. Re: sample size of 13 by Anonymous Coward · · Score: 0

      Ah America, where the only.thing of value is money.

    4. Re: sample size of 13 by Anonymous Coward · · Score: 0

      To support your point, that prick posted from an iPhone, the snootiest of phones.

    5. Re: sample size of 13 by Anonymous Coward · · Score: 0

      In my field of particle physics, the minimum standard is three sigma to publish any claim of "evidence for" an effect, and five sigma to publish any claim of discovery.

  5. Not a Surprise by Cinnamon+Beige · · Score: 4, Interesting

    I've had a lot of teachers whose specialty was in this area, and honestly this is kind of the equivalent of 'We checked, water is wet.' ADHD is basically a bandwidth problem--people with attention deficit disorders (there's several) lack the standard suite of preprocessing filters on their incoming data. These normally are present to basically try to get you to stick with what (the filters judge to be) the important stuff in the incoming data is--without these filters, you're attempting to drink from the proverbial firehose. Hyperactivity is the most common method by which the brain attempts to cope--"Maybe if we move really really really fast we can get all this sorted!"

    There's other strategies, too, such as 'shut down' and 'increase processing power' which have their own relative issues and your attention is still going to be not working like what is classed as 'normal'--in some populations, ADD is normal, because assumptions about what is/isn't important in your environment tended to get selected against instead of heavily agricultural populations where we strongly selected for the ability to not be too bothered by spending many hours staring at the hind end of a draft animal... It's not shot; you can get hyperfocus and flow, where your attention is very tightly focused on doing a task, vastly more easily than the normal population.

    There is, however, one thing about this that's surprising--and that's that you get the same kind of effects in normal people. One of the old methods for confirming an ADD diagnosis is that you had an atypical reaction to stimulants...which Adderall and Ritalin are. To be specific, they're amphetamines...

    1. Re:Not a Surprise by alvinrod · · Score: 1

      which Adderall and Ritalin are. To be specific, they're amphetamines...

      Take a look at the chemical formulas for Adderall and meth sometime.

      I think a lot of ADHD problems would go away if we just let kids run around some more. I've known a fair number of people who've been put into that bucket and physical exertion does a lot to mitigate the effects. Extra PE time might also help with the obesity epidemic as well.

    2. Re:Not a Surprise by Anonymous Coward · · Score: 0

      It's funny because there's nothing deranged about hanging a traitor, but your head is so far up your ass kissing Putin's cock for Trump you don't even realize you're doing it. Don't worry, he'll get treatment in Federal prison.

      Right before they hang the obese treasonous faggot.

    3. Re:Not a Surprise by superwiz · · Score: 1

      riiight... walk it off... does that work on heart attacks and cancers, too?

      --
      Any guest worker system is indistinguishable from indentured servitude.
    4. Re: Not a Surprise by Anonymous Coward · · Score: 0

      Were you always this much of a dumbass?

    5. Re:Not a Surprise by MrKaos · · Score: 1

      which Adderall and Ritalin are. To be specific, they're amphetamines...

      Take a look at the chemical formulas for Adderall and meth sometime. I think a lot of ADHD problems would go away if we just let kids run around some more. I've known a fair number of people who've been put into that bucket and physical exertion does a lot to mitigate the effects. Extra PE time might also help with the obesity epidemic as well.

      I think they are suffering psychological abuse from their parents, who inherited it from their parents and so on. That adderall acts on the working memory suggests it is trying to make kids forget the source of the emotional pain they are suffering, instead of resolving it.

      All common sources of the type of personality disorders that are reaching epidemic proportions. Mental illness is contagious and most of us inherit it from our parents in some form.

      --
      My ism, it's full of beliefs.
    6. Re: Not a Surprise by Anonymous Coward · · Score: 0

      I'm sure my post will be censored to -1 by the same abusive moderators who always censor my posts about Trump. I'm so sick of the fucking moderators censoring my posts to avoid the truth that Trump is a traitor. There really needs to be more accountability on this site, like publicly disclosing the usernames of moderators responsible for negative moderation. Moderators are ruining Slashdot by censoring useful discussion like my posts to -1. The single biggest reason that so many longtime users have left this site is because of the abusive moderation. If Slashdot wants to survive, it will be necessary to eliminate moderation, or at least get rid of the moderators who keep censoring useful posts like mine to -1.

    7. Re:Not a Surprise by Cinnamon+Beige · · Score: 2

      which Adderall and Ritalin are. To be specific, they're amphetamines...

      Take a look at the chemical formulas for Adderall and meth sometime.

      I wandered into neuroscience from biochemistry, and actually am thinking of seeing if I can get a copy of this study to read, even though it is kinda stating the obvious.

      I think a lot of ADHD problems would go away if we just let kids run around some more. I've known a fair number of people who've been put into that bucket and physical exertion does a lot to mitigate the effects. Extra PE time might also help with the obesity epidemic as well.

      I can assure you that a lot of it is, in fact, due to cutting back on the time kids get to actually exercise--that, and schools get extra money for each student diagnosed. A lot of the diagnosis is also somewhere around the 'people should be at least sued for this' end of half-assed, too--I've heard of diagnosis being basically done on the word of a school counselor who is mostly relying on teachers' complaints with the medication tossed on their word by a general practitioner. Most teachers go off of how much attention a student is paying--and don't necessarily consider such possibilities as the student being bored to death, needing to have time to indulge in physical activity, or suffers from a physical condition commonly known as 'being male' when it gets really stupidly bad.

      This is not how you should be diagnosing neurological issues--and yes, it is one. You also don't see the behavioral help that's pretty much required (because the drugs have no measurable effect after ~2 years) put in because that's hard and would require one of the parties spend money on the problem instead of just give the kid pills--which, once again, are amphetamines and people with ADHD aren't that different neurologically. Amphetamine side effects and problems are still going to be there, including amphetamine psychosis and the fun that happens when the idiot doctor prescribes sleeping pills because 24/7 amphetamines do screw with your sleep, who knew?

      ADHD definitely exists--but the sheer incompetence, lack of required skills, and perverse incentives here all combine to make it unfortunately very likely that most people who have been diagnosed with it...probably don't actually have it.

    8. Re: Not a Surprise by Anonymous Coward · · Score: 0

      "publicly disclosing the usernames"

      You first asshole. If anyone agreed with you the mod would be overturned for sure.

    9. Re:Not a Surprise by Khyber · · Score: 2

      In some cases, YES, it does. Your body is capable of growing new arteries and veins if it detects a shut off of oxygen to various parts of the body. Whether it does it fast enough to keep you alive is a different story.

      --
      Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
    10. Re:Not a Surprise by netlag1 · · Score: 1
      People with ADD do have atypical reactions to stimulants... it calms them down. I had serious ADHD as a kid, and taking amphetamine (dexedrine) controlled it. I mostly outgrew it, but as an adult decades later, I can drink a bunch of caffeine at night and have no trouble sleeping.

      There is, however, one thing about this that's surprising--and that's that you get the same kind of effects in normal people. One of the old methods for confirming an ADD diagnosis is that you had an atypical reaction to stimulants...which Adderall and Ritalin are. To be specific, they're amphetamines...

    11. Re:Not a Surprise by Anonymous Coward · · Score: 0

      You literally have no idea what you're talking about. Are you a holocaust denier too?

    12. Re:Not a Surprise by Anonymous Coward · · Score: 0

      Wow, you're a real uninformed idiot. I hope for the sake of all people with mental illness, myself include, that you never make it into the field.

    13. Re:Not a Surprise by Anonymous Coward · · Score: 0

      And then there's the "Centor for Self Leadership", the scam psychiatric organization that is anti-training and anti-licenses, but still charges $1300/weekend from bozos who never studied or did actual clinical work in their life. And oh, their training has no grades or certification, because "those don't prove anything".

      They love encouraging never-trained people with "untapped therapeutic talent" as "ADHD coaches" and "psychotherapists", which don't require licenses in most states, and encouraging them to serve without ever *getting* any formal training. These very dangerous fools then misdiagnose their suckers as having "post-traumatic stress" and "abuse", and encourage their victims to *hide* what these fools do as "personal and private to the patient", refusing all communication with their medical professionals. They especially hide it rom the real psychiatrists they teach their victims to scam for psycho-active medicaitons like.... wait for it... wait for it..... Adderall. See, once the victims start taking the psycho-actives. the victims can get up in the morning. (Trust me, if you take Adderall in the morning, you *will* get up.) The fraud then takes credit for the victim "being empowered". The psycho-pharmacology just "gave them another spoon". Ihe fraud continues as the therapist *actively hinders* any further progress with their destructive "therapy". They're like chiropractors and homeopaths, extending treatment as "always beneficial" without actually doing the work a competent professional does.

    14. Re:Not a Surprise by MrKaos · · Score: 1

      You literally have no idea what you're talking about. Are you a holocaust denier too?

      I've been writing a book about these types of personality disorders and how people can heal themselves from this type of mental illness. I know a lot more about this subject than I want to know.

      --
      My ism, it's full of beliefs.
    15. Re:Not a Surprise by Cinnamon+Beige · · Score: 1

      What I just described is, depressingly enough, taken from multiple case studies and basic awareness of how you're actually supposed to handle psychiatric medications--if you're on them and nobody's taken the time to tell you, fuckups with your meds can make your mental health problems worse and yes, you should keep track of & mention side effects. This is something your doctors are supposed to tell you, especially since sometimes it can get weird, such as one patient with bipolar who had a psychotic episode because of energy drinks.

      I've known people who were fucked over by doctors who...didn't, both personally and through case studies. What I described is actually a common pattern I've seen in case studies of ADHD patients--specifically, ones who had psychotic breaks. That's...more or less to be expected if you mix Ritalin or Adderall with sleeping pills, and with uppers--stimulants--in general there is always a risk. (This includes at least one case caffeine psychosis--the one I managed to hear the details of, the woman managed to drink a very impressive amount of coffee in a very short period of time, and then tried to kill a friend.)

    16. Re:Not a Surprise by Anonymous Coward · · Score: 0

      Ritalin is not an amphetamine damm you people are pharmaco-ignorant

    17. Re:Not a Surprise by Megol · · Score: 1

      Amphetamine psychosis? How about providing any study that shows this being an issue when treating ADHD? I can't find anything but my search skills may be lacking. It is an issue when abusing amphetamines however ADHD is treated with much lower doses than is required to provide recreational effects.

    18. Re:Not a Surprise by Trickster+Paean · · Score: 1

      Good comment, but I do have one clarification.

      While Ritalin (methylphenidate) is a stimulant, it is not an amphetamine, but instead a phenethylamine. It works differently from amphetamine, since it works primarily as a dopamine reuptake inhibitor, whereas amphetamines increase the activity of neurotransmitters like dopamine. To simplify it, Ritalin works by keeping the brain from removing dopamine, while adderall works by increasing dopamine release. That's part of the reason why some people with ADHD respond better to Ritalin than Adderall, and vice versa.

    19. Re:Not a Surprise by Cinnamon+Beige · · Score: 1

      riiight... walk it off... does that work on heart attacks and cancers, too?

      It's unfortunately not walk it off: The ADHD problem that'd go away is one of misdiagnosis. A lot of places are using outright dismal diagnostic methods--poor accuracy and poor validity combining to produce a false positive rate that ought to be unacceptable for anything commonly perceived as a mental health issue and/or treated with drugs that can have serious side effects.

      It'd be rather like diagnosing any and all pains in the chest as a heart attack, even when you've got a knife sticking out of the patient. Sometimes you'll be right, but...

    20. Re:Not a Surprise by Cinnamon+Beige · · Score: 1

      Ritalin is not an amphetamine damm you people are pharmaco-ignorant

      Methylphenidate is close enough that it appears to work very much like dextroamphetamine. It is considered to be in the amphetamine family, typically, and may be* subject to the same laws as amphetamines--right down to the same legal issues if you try to take any with you when crossing the border, even if you obtained it perfectly legally and have the medical documentation to prove it.

      * I am not a lawyer, nor employed in any field that requires I know the logistics of obtaining controlled substances or taking them across international borders beyond those very specific cases I have had to know. Do your own research before you go--especially since laws can change--and do not expect it to be necessarily easily found, and the ease of access can and does vary between countries. That said, Ritalin is under the same rules as other drugs considered amphetamines in all countries I've had reason to know the details of; if you cannot function without Ritalin or Adderall, don't visit Japan.

    21. Re:Not a Surprise by Billly+Gates · · Score: 1

      An atypical reaction includes focus which it does do.

      Unfortunately, those of us on ADHD also get the nasty side effects too the article talks about. But starting a task is what helps. My ADHD is so bad my apartment is a mess half the time and I barely even cook. On Adderall it was squeky clean and I was learning new recipes and felt energy not to get overwhelmed on the simpliests tasks starting.

      Unfortunately, it is true the side effects were too bad. I had to quit taking it as I would be fired if I took it again and started acting aggressively and talking faster than an auctioneer at work.

    22. Re:Not a Surprise by Cinnamon+Beige · · Score: 1

      Amphetamine psychosis? How about providing any study that shows this being an issue when treating ADHD? I can't find anything but my search skills may be lacking. It is an issue when abusing amphetamines however ADHD is treated with much lower doses than is required to provide recreational effects.

      As far as I know, there no study checking it at all, which is actually a problem because drug-induced psychosis on the whole is definitely not dose-dependent--it's not as simple as high dose=psychosis, especially since with drugs in the family it seems to be something which will happen if you take it for long enough regardless of how careful you have been about the dose...and some people never get symptoms while others it seems to just be one day they pulled the trigger and got the loaded chamber, so to speak. I have seen several case studies of people on theraputic doses for ADHD having psychosis turn up after they'd been on the meds for a while, however.

      Honestly, the whole thing could be vastly better studied, but I doubt that'll happen until some drug finally starts inducing it with noticeable reliability while trying to get approved by the FDA.

  6. Oh, almost forgot... by Cinnamon+Beige · · Score: 2

    FYI: Working memory is basically the RAM of the brain--it's short-term holding for stuff you're processing and using, which is why it's called working memory. One of the things you check for if somebody who should be doing well in school but isn't? Is if their working memory is functioning correctly.

    Focus and attention aren't anywhere near as important. You can only be vaguely paying attention and still retain a surprising amount of information, but you need your working memory to remember the start of a paragraph when you reach its end, and other things rather important to the ability to reason and make good choices.

    So it's not just that it didn't make anybody 'smarter,' it actually managed to hose something you direly need working to be smart. Though, if amphetamines in general screw with the working memory, that explains so much about the life choices of amphetamine addicts...

    1. Re:Oh, almost forgot... by Anonymice · · Score: 2

      I've been diagnosed with ADHD since I was a child, and use medication selectively today, adjusting my dosage depending on the demands of the day & how I'm feeling (I only take my full dosage on "bad" days).

      Your description is fairly spot on. Anecdotally however, I'm not sure the medication actually has much of a direct affect on memory, it simply helps in maintaining focus on the right things, which in turn helps you record the right things.

    2. Re: Oh, almost forgot... by Anonymous Coward · · Score: 1

      It doesn't and it's not intended to. The medication is intended to help the brain control where the focus is directed, not increase working memory or focus.

      The misconception here is that people see the change in treated ADDers and assume they can get that by taking the pills and there's no real evidence that it works like that.

    3. Re:Oh, almost forgot... by Cinnamon+Beige · · Score: 2

      I've been diagnosed with ADHD since I was a child, and use medication selectively today, adjusting my dosage depending on the demands of the day & how I'm feeling (I only take my full dosage on "bad" days).

      Your description is fairly spot on. Anecdotally however, I'm not sure the medication actually has much of a direct affect on memory, it simply helps in maintaining focus on the right things, which in turn helps you record the right things.

      Working memory is distinct from short-term and long-term memory--the things people normally think of as memory. Those are more like the write buffer to the hard drive & the hard drive itself.

      That said, you might want to look into flow--hyperfocus is when you find your attention stuck on something and it's not something you want to be paying attention to exclusively, flow is the state of attention you're in when you hit the zone. I've lost days that way. ADHD actually makes it easier to reach these states--it's not that you don't have any attention span, it's that most things won't hold it well...but what holds it will do so really well. (Anecdotally: Music works for me for reaching flow easily. I use endless repeats and long playlists--radio only if there's next to no interruptions to the music--and sometimes I have to have really strangely precise matches between music and what I'm trying to focus on.)

    4. Re:Oh, almost forgot... by Khyber · · Score: 2

      "Anecdotally however, I'm not sure the medication actually has much of a direct affect on memory"

      Judging by your UID, you're a young millennial.

      Come back in 15 more years when you start seeing the extended effects of those amphetamines on your nervous system. I took that shit for 12 years, from age 6 to 18. The damage it did is quite noticable. You'll start thinking you're getting Alzheimer's around 35 if you took it as young and as long as I did.

      --
      Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
    5. Re:Oh, almost forgot... by Anonymous Coward · · Score: 0

      Or alternatively, that could be part of the condition. I was undiagnosed in my youth (parents didn't believe in mental illness), so wasn't exposed to amphetamines until recent years, yet I've got that whole Alzheimer's like memory going on, and have had since before diagnosis.

    6. Re:Oh, almost forgot... by Anonymous Coward · · Score: 0

      Side-note, my uid is ~9x lower than yours, if that's how we measure age these days.

    7. Re:Oh, almost forgot... by Anonymous Coward · · Score: 0

      If we're going with that example: Amphetamines overclock the body and the brain. Same as a computer you get memory errors and wear components faster. Your processor doesn't get "smarter" or grow transistors either, just everything is sped up. Just like intel "turbo" mode you don't want it on all the time.

    8. Re:Oh, almost forgot... by Megol · · Score: 1

      One thing for sure: you aren't a scientist.

      UID isn't indicative of age, just of when the user registered here.
      Your memory problems aren't shown to be linked to your amphetamine use.
      No evidence is presented that it isn't the underlying condition that was treated with amphetamines that cause these effects and not the treatment itself.
      You have not shown that those problems aren't caused by other things, there are a lot of things that can influence mental performance including memory.
      There is no evidence that you actually have worse memory than is normal for others in the same age group.
      You are trying to draw conclusions from (probably) non-verified data of sample size one. Most likely self-reported which of course have a huge amount of biasing.

    9. Re:Oh, almost forgot... by Anonymice · · Score: 1

      Judging by your UID, you're a young millennial.

      Come back in 15 more years when you start seeing the extended effects of those amphetamines on your nervous system. I took that shit for 12 years, from age 6 to 18. The damage it did is quite noticable. You'll start thinking you're getting Alzheimer's around 35 if you took it as young and as long as I did.

      It took me the best part of a decade to get around to actually registering, I've been following /. for almost 20 years now.

      I was on a high dose of ritalin from the age of 4, until about 12. I was a victim of all of that bullshit prejudice against the treatment of ADD & fell into the trap of believing all I lacked was disciplined focus & motivation. I pretty much dropped out of school after that.

      I had reasonable success in my chosen niche of IT, but I ended up crawling back to the psychiatrist in my mid-20s, as my poor executive skills & time management was playing havoc on my life.

      Since going back & accepting help, I'm now the owner of a successful business, manage a couple of federal datacenters, own my own home, & have a family.
      Those meds (& a patient wife) gave me the stability I needed to actually make a success of my life.

      It's true that the drugs are strong, however I don't take them every day, moderate my dosages, and live an otherwise healthy & active life. But I call bullshit on the suggestion that being on them for a 12 year period of your life has given you the symptoms of Alzheimer's today - effects are still being studied, however we've now got over 30 years of literally millions of patients being treated on amphetamines for ADD, and a good 70+ years since they were first widely used. If the mid-term side-effects were that extreme, it'd have become common knowledge long ago.

      I suspect there's a very good chance that what you are identifying as Alzheimer's are actually the symptoms of untreated ADD. Specifically, memory problems due to a mind that's unable to maintain a line of thought.

    10. Re:Oh, almost forgot... by Anonymice · · Score: 1

      He's confusing correlation with causation. ADD's impact on attention, executive skills, & being able to maintain a line of thought, can lead to effects that seem very much like a memory disorder.

      When you've got a constant stream of multiple internal dialogues & other distractions circling around your head, it can be quite easy to forget why you walked into a room, where you just put your keys, or the name of the person you met literally only 30 seconds ago.

    11. Re:Oh, almost forgot... by Anonymous Coward · · Score: 0

      Oh believe me, we've noticed.

  7. Who care about the abusers? by Revek · · Score: 1

    Do they work on the people who need it?

  8. wait by superwiz · · Score: 2

    You mean the drug prescribed for Attention Deficit Disorder treated attention deficit, but wasn't helpful in treating cognitive deficit? And that's why it doesn't do what people think it does? Umm... what?

    --
    Any guest worker system is indistinguishable from indentured servitude.
  9. they're doing *EXACTLY* what *I* think they do.. by Anonymous Coward · · Score: 1

    they make big pharma and those who write the scripts for the drugs a lot of money

  10. Re: I have CDHD by Anonymous Coward · · Score: 0

    Chris, you need the money more than me. Keep it!
    (I heard goat food is through the roof right now in San José! How many do you feed!?)

  11. Re: I have CDHD by Anonymous Coward · · Score: 0

    How much will you pay for the identity of the guy who wanted to pack you into a crate and push you out the back of a Hercules?

  12. No its not by ArchieBunker · · Score: 1

    Remember when the cure for ADHD was an ass whoopin'? Pepperidge Farm remembers. Same goes for kids acting up in a restaurant. In the old days you took them out to the car. When they came back they weren't acting up anymore.

    --
    Only the State obtains its revenue by coercion. - Murray Rothbard
    1. Re:No its not by Anonymous Coward · · Score: 0

      The same time when people were given electroshock treatment and ice baths until they could pretend to be cured. Only then would the torture stop. If they did not smart up fast enough they would be lobotomized, leaving their mind within a prison in their own maimed brain.

      The same time when an uppity wife gets a bloody lip and a black eye. She wont do that again.

      So long as it works right Archie?

    2. Re: No its not by Bing+Tsher+E · · Score: 1

      Why did you stop there? People historically have done many horrible things for arbitraty reasons, which you can conflate with common sense when you want to defend coddling as you apparently do.

    3. Re:No its not by drinkypoo · · Score: 1

      In the old days you took them out to the car. When they came back they weren't acting up anymore.

      Yeah, instead they just grew up to beat their wives and their kids. Great plan.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    4. Re:No its not by Megol · · Score: 1

      ECT is still a standard treatment, the most effective treatment for a number of mental problems.
      I've had it as have a lot of people (it's far from unusual). Of course that's a "modern" variant that includes sedation and muscle relaxants which normally at worst gives some muscle ache (due to convulsions), a headache (due to increased blood pressure) and temporary amnesia.

      Unlike your description ECT, insulin shock treatment and ice baths weren't used for torture but because they provided real positive effects. Lobotomy is a completely different thing but I have to mention that it is still used in a few exceptional cases.

    5. Re:No its not by ArchieBunker · · Score: 1

      There is a difference between "beating" your kids and beating your kids.

      --
      Only the State obtains its revenue by coercion. - Murray Rothbard
  13. post by Anonymous Coward · · Score: 0

    post

  14. Shit, this means by Anonymous Coward · · Score: 0

    Trump can't be cured.

  15. Speed by geekymachoman · · Score: 2, Interesting

    I'm glad we have scientists that brand speed and then sell it to people for profit, legally.

    Wish they did it with cocaine and weed too, I'm sure we can find an excuse WHY it's a good idea. Just invent another imaginary illness, or "condition".

    1. Re:Speed by Anonymous Coward · · Score: 1

      Cocaine is legally sold for use as an anaesthetic, which is most commonly used in eye surgery.

    2. Re:Speed by cmseagle · · Score: 1

      Are you saying that attention deficit disorders are an "imaginary illness"? And that cocaine and marijuana don't have legitimate medical uses? I'll give you over-diagnosed, maybe, but certainly not imaginary.

    3. Re:Speed by Anonymous Coward · · Score: 0

      For weed, move north. Stuff goes on sale in the fall - can buy in in the booze store I think.

    4. Re:Speed by demonlapin · · Score: 3, Insightful

      It was first used for eye surgery, but when it's used today, it's primarily in nasal work - it's both a vasoconstrictor and a local anesthetic. Due to concerns about diversion, though, it's almost never used. I've been an anesthesiologist for twelve years, and I've seen it used once.

    5. Re: Speed by Anonymous Coward · · Score: 0

      THC is sold legally in pull form for an obscene amount it is called Marisol.

    6. Re:Speed by Anonymous Coward · · Score: 0

      That's actually humorous for unfortunate reasons.

    7. Re:Speed by Anonymous Coward · · Score: 0

      Ritalin is a dopamine reuptake inhibitor, functioning in a very similar manner to cocaine by keeping the dopamine in the synapse and preventing it from being reabsorbed and reused. It is not neurotoxic, and in fact protects from amphetamine neurotoxicity. Vyvanse and Adderall are amphetamines and increase the release of dopamine into the synapse. Coke and meth, or ritalin and adderall, when combined have a synergistic dopamine releasing/reuptake blocking effect causing a much larger dopamine spike.

    8. Re:Speed by DCFusor · · Score: 1

      Double-blind, utter BS. If it works, you can tell it's working by being in the body/brain it's working on, easy.

      --
      Why guess when you can know? Measure!
    9. Re:Speed by Peter+P+Peters · · Score: 1

      I'm glad we have scientists that brand speed and then sell it to people for profit, legally. Wish they did it with cocaine and weed too, I'm sure we can find an excuse WHY it's a good idea.

      Or you know do actual science and make decisions based on that...

      Just invent another imaginary illness, or "condition".

      The science is there. Feel free to publish your own studies if you have information not already presented.

  16. More garbage masquerading as science by Anonymous Coward · · Score: 0

    Sample size:13. End of story.

    I dont give a good god damn how well designed some bullshit study was. The sample size is too small. The results are worthless. When sample size is ridiculously small, remember that correlation is not causation for celebration when a study was but mere mental masturbation.

  17. Don't hype a study with such a small sample size. by El+Jynx · · Score: 2

    I don't care how perfectly well you've set up your experiment. 13 people does not a respectable sample size make. It's all too likely that a fluke is majorly skewing the results. I don't even understand what this post is doing here. We should know better.

    --
    A positive attitude may not solve all your problems, but it will annoy enough people to make it well worth the effort.
  18. How do they know what I think? by Anonymous Coward · · Score: 0

    Can you call yourself a scientist if you make that kind of broad assumptions and precent them as truth?

  19. They're not supposed to make you smarter by Opportunist · · Score: 2

    They're supposed to make you pay attention to what you're told, not to reflect upon it.

    Working as designed.

    --
    We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    1. Re:They're not supposed to make you smarter by Megol · · Score: 1

      I think you just did that without the drugs...

  20. Anti-drugs test for student by Anonymous Coward · · Score: 0

    Anti-drugs test for student as for sportsman, this is what we need.

    What works best for exams is: studying all along the year at a sustainable rhythm, and keeping sleeping time under control (8-9 hours every nights). If you need doping product, you are doing something wrong!

  21. Science? by Anonymous Coward · · Score: 0

    Homeopathy on steroids. What's more interesting is that the targeted audience would be shocked and demand the burning of the Pharmaceutical company that would have sold pills tested in such "rigurous conditions".

    Yet the article is very relevant showing the education quality of PhD graduates at the said diploma mills.

  22. What is ADHD? by hwihyw · · Score: 1

    Here is the top youtube video showing ADHD vs non-ADHD child. Does the girl have ADHD or is she just anxious? Look at how she sits and how the boy sits. Count how many times the boy smiles and how many times the girl smiles (hint: zero). If the girl is the top example of ADHD, I can give 100 children ADHD interviews and classify a large portion as having ADHD. Of course I would be impartial and have no stake in classifying kids as having ADHD and charging for weekly counseling, writing prescriptions, etc.

  23. Eh...Placebo? by Anonymous Coward · · Score: 0

    Let's be honest. You can't placebo a pill like this where it has such an immediate and noticeable physiological effect. You'd know 100% whether or not you got a sugar pill or Adderall.

  24. Adderall made me ... by Anonymous Coward · · Score: 0

    Adderall made me forget what a terrible student I am.

    My parents wasted their money sending me to University when I might have instead gotten my shit together working part time and going to community college.

  25. Re:Don't hype a study with such a small sample siz by Anonymous Coward · · Score: 0

    If I flip a coin heads 13 times in a row we can be fairly certain the odds are nowhere near 1/2.

  26. what do you expect? by ooloorie · · Score: 1

    ADHD Drugs Aren't Doing What You Think, Scientists Warn

    I think that feeding psychoactive drugs to boys because their teachers don't know how to raise boys and are boring and dumb is going to produce adults that are angry, poorly educated, and anti-social. And what I "think" these drugs do seems to be exactly what they are doing.

  27. still looking for a good drug for my ADHD by FeelGood314 · · Score: 1

    I've actually hired a babysitter for myself just to keep me focused and to not get distracted. $14/hr sucks but it currently is the only way I can do work most days. I've tried quite a few ADHD drugs and they either have no effect or they make me drowsy. By drowsy I mean do not operate any motor vehicle drowsy. My doctor failed to mention that part.

  28. Errm, yes, they are doing *exactly* .... by Qbertino · · Score: 1

    ... what people think: Enhancing attention and focus. It says, right there in the Metaarticle. So thanks for confirming that.

    Sidenote: I'd stear clear from any medication, even when in a tough spot at college.
    Lack of excersize, bad nutrition, bad sleep hygene, excess media consumption and consumerism are what I have found to correlate with symptoms generally regarded as "ADHD".

    --
    We suffer more in our imagination than in reality. - Seneca
  29. Some ADHD Advice by Qbertino · · Score: 1

    still looking for a good drug for my ADHD

    Some advice:

    #1 Nutrition. Stop any type of sugar. Like, don't freaking even touch the stuff for 10 weeks and you'll notice a significant difference in cognitive performance. Promise. Avoid processed foods, preferably like the plague. Learn to cook/prepare your own meals. Do paleo or some other hippster compliant diet if that helps you. I've become a bit of a salad expert. My salads are full meals with grilled veggies or mushrooms or seitan & tofu as topping. Shop organic and rather skip that next piece of expensive hardware your eyeing. I shop organic and am typing this on a refurbished ThinkPad. Wouldn't want it the other way around.

    #2 Social Media: Stop it. No facebook, no whatsapp or instagram. I message with my girlfriend, my daughter and two to three of my buddies and that's it. It's basically email. Any more would be unhealthy. The only "addiction" I have in this area is slashdot (duh), and there I try to write meaningful comments (duh again). I'd like to tune down a little, but to be fair, the threads I join are ususally a meaningful and ongoing discussion, so it's not a complete waste of time - also due to us all leaning to the smarter side :-) . Although it does cut time away from my real life. Again: Facebookers are zombies. On the tram I sometimes the only one with his head up. I look out the window and muse, while others are addicted to their streams. ... Yes, I sometimes refresh my slashdot comments to see my ratings, but that's a habbit I'm working on to change. And I can, because I know how good real life feels vis-a-vis facebook and whatscrap.

    #3 Media consumption: Stop TV and avoid anything else as much as possible. The lesser the better. A movie a quarter should be the rule of thumb. Seriously. Limit your video game time to one game and a maximum of 3 hours per week. Fill the gained time with excersize (see below). For gaming chose P&P RPGs with a group of friends or boardgames over videogames (on or offline).

    #4 Excersize. This is a big one. Can't emphasize this one enough. My wellbeing directly correlates with how much excersize I have. Do martial arts, social dancing, yoga, calisthenics or something like that at least 3 times a week, better yet 4 or 5 times a week. Freeclimbing, boldering, paraglying and surfing (the real kind) are awesome too. I did Argentine Tango for 10 years, traveling around Europe and mingling with the scene of Tango-Bums/Tango-Nomads, at least 3 times a week which had the added benefit of meeting an abundance of very, *very* cute ladies and having the occasional intimate episode coming out of that, and now I'm moving into swimming and yoga. I'm doing this because now I have a girlfriend (Tango dancer/teacher) and the most amazing sex ever, which significantly lowers the attraction of Tango for me. :-) I just swam 800 meters this afternoon. Awesome. Excersize and make a routine or some sort of excersize an essential part of your life. Your ADHD will recede below percievable levels and people will know you for being a generally younger and healthier self. Your concentration and brain performance will rise significantly, I promise. And the ladies will start turning their heads too. I promise that aswell.

    #5 Limit screen time. This is a big one for computer nerds like us. I work 20 hours/week. I earn enough. I live minimalistic (highly recommended) and would rather do yoga 90 minutes per day than sit in front of the screen 12 hours in a row. Doing part time helps you focus on automating your tedious IT work and focusing on the fun parts of reality. When I only sit for 4 hours per session max. it's way easyer for me to focus on that one technology than spreading myself to thin with 5 or 10 at a time (we've all been there). Again: Limit screen time. 6 hours per day should be enough for any expert who knows how to automate the tedious computer work, i.e. programm.

    #6 Stay away from d

    --
    We suffer more in our imagination than in reality. - Seneca
  30. Placebo *sugar* pill by Reaper9889 · · Score: 1

    I am wondering if it is reasonably to give people sugar pills as a placebo to test these kinds of things. I would think that sugar does give people energy but perhaps less attention?

  31. crack crack crack want some crack? by Anonymous Coward · · Score: 0

    You'll say whatever it takes to justify your addiction. That's fine, just realize that's what you're doing.

    Whether it is medically necessary or not, crackheads gonna crack.

  32. WHOOP. DAT. ASS. by Anonymous Coward · · Score: 0

    I cured my son's ADD by whippin that ass for a week solid, multiple times per day, when he was in the 3rd grade. NEVER another complaint from another teacher or a call from a principal afterwards. Now he's still fucked up mentally, but at least he's isn't jumping around in your face screaming like an asshole asspie.

    He can sit down, shut the fuck up, and stew in his own self loathing like the rest of us have to. THAT is life. It doesn't give a fuck about your feelings.

  33. Memory == Smarts? by Anonymous Coward · · Score: 0

    While students on Adderall did make fewer errors on a reaction time test, it actually worsened working memory, as shown by a decline in performance on a task where they had to repeat sequences of numbers. In short, Adderall improved focus and attention -- but it didn't actually make anyone smarter.

    You keep using that word. I do not think it means what you think it means.

    Being able to remember facts is not an indication of 'smartness'. Being able to connect facts into useful new constructs is.

    Some of the smartest people I've known have had horrible short-term memory (think of the stereotypical absent-minded professor). Conversely, some of the less smart people I know have outstanding memories (they learn by wrote, after all) but they can't connect the dots to create any original ideas.

    Gawd, I miss the days when tech was run by nerds who understood this (and other concepts like the Dunning-Kruger effect).

  34. Really? by BrookSmith · · Score: 1

    Really? I would have thought prescribing amphetamines to people would do exactly what you think. I must say - I'm surprised.

  35. Re:Don't hype a study with such a small sample siz by Peter+P+Peters · · Score: 1

    I don't care how perfectly well you've set up your experiment. 13 people does not a respectable sample size make.

    Because you said so? Feel free to tell us which part of this you disagree with: https://en.wikipedia.org/wiki/...

    We should know better.

    Yes, yes we should....

  36. Not what it's designed for. by Anonymous Coward · · Score: 0

    Who gives a s**t if people are using it as an illegal drug and it's not monitored properly by an actual physician. As a parent of a child with Hyperactivity who tried everything before drugs, then had to find the right one for him, I have no sympathy.

    In a person that needs it, it does what it's supposed to: take them down a touch so they can have a chance to make the right decisions. You don't always do that, but this drug helps people who have a genuine problem.

    I'll also add a brief thanks for all the hoops I have to jump through with physical prescription only rules, no refill rules and other precautions the state had to add . . .