Anyways, the reason nobody works on these is probably because our existing antibiotics already work really well, likewise it wouldn't be terribly practical to develop more.
No! No! Bacteria have been evolving antibiotic resistance and things are getting quite desperate, especially in hospital settings. Newer and more potent antibiotics are urgently needed. Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE) and multi-drug-resistant Mycobacterium tuberculosis (MDR-TB) are well-known examples of superbugs. The latest are NDM-1 bacteria that have acquired the ability to defeat carbapenems, the antibiotics of last resort when all else fails. And these are failing too. There is an ongoing arms race between bacteria and antibiotics and it has always been so since the introduction of penicillin. The bacteria are getting ahead and we need new antibiotics since yesterday.
High speed trains are awesome, and they're great for prestige and getting customers to buy that technology. Yet they're out of price range for the majority of customers.
Maybe not? This from a recent World Bank report: "As of October 1, 2014, over 2.9 billion passengers are estimated to have taken a trip in a China Rail - High
Speed train (called CRH services), with traffic growing from 128 million in 2008 to 672 million in 2013, or
about 39 percent growth per annum since 2008. In 2013, 530 million of those CRH trips took place on
passenger dedicated HSR lines. In 2013, China HSR lines carried slightly more HSR passenger-km (214
billion) than the rest of the world combined. This represented about 2.5 times the HSR passenger-km of
Japan, the second largest country in terms of HSR traffic. These are substantial numbers for a system
that is still in its early days."
But what about the Fourth Crusade when the Byzantines themselves were attacked and Constantinople - the richest city in Christendom - was sacked, looted and raped by the western Crusaders? It was so awful, shameful and painful that 800 years later Pope John Paul II thought it necessary to apologize for it. There was nothing "good" about that one.
That will create the ultimate anti-Apple. Amazon's store is the only one right now that can compete with Apple's App store and if that becomes the de facto Google Android store, that will mean the first real competitor to the iDevice/App Store ecosystem. And Google's cloud + Amazon's cloud will be mother of all clouds too.
Simple query of a well-known statesman. Google gets it right with its very first response. Bing doesn't seem to know what I want. Alpha doesn't have a clue.
Google 1 - Bing 0
Bing and Alpha have a lot of catching up to do. And Google doesn't blink even when I get the spelling wrong as in "Winston Chrchill's Father"
Shakespeare was the conduit through which Marlowe published his works after he (Marlowe) had to "disappear" through a faked death. Marlowe was a wanted man because of his outspokenness and involvement in the plots and intrigues of the Elizabethan age. The facts about Shakespeare's life that can be determined with absolute certainty make it unlikely that he could be the writer of the great plays, sonnets, and poems that are ascribed to him.
I can't understand why he is doing this. Surely he is rich enough to afford to have noble principles and values and doesn't have to resort to such distasteful methods to enrich himself. And he is also a very smart person. Surely his time and money can be better spent actually implementing useful ideas. Or maybe this is his way of showing how absurd and unfair the current patent system is to goad people into taking action to reform it?
"Many studies demonstrate that differences in mating
signals are used by incipient species in recognizing potential mates
or sexual competitors (i.e., species recognition). Little is known, however, about the genetic changes responsible for these differences in
mating signals. Populations of the Monarcha castaneiventris flycatcher vary in plumage color across the Solomon Islands, with a subspecies
on Makira Island having chestnut bellies and blue-black upper parts
(Monarcha castaneiventris megarhynchus) and a subspecies on neighboring satellite islands being entirely blue-black (melanic; Monarcha castaneiventris ugiensis). Here we show that a single nonsynonymous point mutation in the melanocortin-1 receptor (MC1R) gene is present in all melanic birds from one island (Santa Ana) but absent in all chestnut-bellied birds from Makira Island, implicating this mutation in causing melanism. Birds from a second satellite island (Ugi)
do not show the same perfect association between this MC1R variant
and plumage color, suggesting an alternative mechanism for melanism on this island. Finally, taxidermic mount presentation experiments in Makira (chestnut) and Santa Ana (melanic) suggest that the plumage difference mediates species recognition. Assuming that the signals used in species recognition are also used in mutual mate choice, our results indicate that a single amino acid substitution contributes to speciation."
Add Alito, Scalia, Kennedy, and Thomas - they are also Catholic and somewhere between very and fairly conservative.
OMG! There goes Roe vs Wade! But seriously, what I meant was right-to-life groups that exist to specifically oppose abortion. Not all Catholics are antiabortion.
I have to admit though that it is a little alarming that the SCOTUS lacks religious diversity.
Can it boot persistently from the SD of my Eee PC 900 and will the wifi just work out of the box? Have never been able to get any of the earlier releases to do these two things.
But better late than never. The Europeans and East Asians are way ahead in high speed rail and it's just such a shame that there hasn't been a single serious attempt at this in the USA. Even as we speak the 819 km Beijing-Shanghai (top speed 220 mph/360 km/h) is being constructed. Wouldn't it be great to have something like that in the USA? It will cost many, many billions but it will be something useful that the nation can be proud of. Unlike wasteful overseas adventures that have caused only pain and shame.
My one concern is that instead of borrowing from the considerable experience of the Europeans and Japanese, time and money will be wasted to reinvent the wheel. High speed rail is a mature technology and it will be best to do what the Chinese have done: bring in and adapt what the Europeans or Japanese already have.
And who might that viable third person or party be? Ralph Nader? Ross Perot? And how is he or she going raise the hundreds of millions necessary to get elected without the backing of the RNC and DNC? You are in wishful thinking territory over here. Obama (even if don't like him) was the lesser of two evils in the last election.
You mean like the way Yo-Yo Ma, Itzhak Perlman and friends pretended to play at the Inauguration? Or how Pavarotti lip-synced at the Turin Winter Olympics? Or the way the Sydney Symphony Orchestra pretended to play at the Sydney 2000 Olympics? Where parts of the music that the Sydney Symphony pretended to play was actually prerecorded by the Melbourne Symphony!
So which are the laptops with Broadcom chips? I know my Presario V3000 has but I didn't know that when I bought it. I'll be looking more closely for my next laptop purchase. Is there is up-to-date somewhere that I can check?
Thanks for the link! I was right. It was the video that told the police that it was 2 boys and not an adult.
Here's what it says:
After midnight on the day James disappeared, authorities watched the security videos taken at the shopping center, hoping to catch a glimpse of his abductor. They were especially interested in reports of an older man with a ponytail who was at the Strand, who witnesses say approached other children that day. James's video image eventually scattered across the television screen. There he was, with two boys, not the ponytail man. Blurry, jumpy images, almost ghostlike. As they watched in disbelief, they realized they were not dealing with an older pedophile, but two young boys, children themselves. There was no way to identify the two older boys, but the baby's clothing matched Denise's description. They played the tape over and over, watching in horror as James was led toward the exit. Why would two children take another child?
Even if CCTVs don't prevent or solve crimes, in many cases they have provided important clues. And closure. If you are parent of a child victim, having some knowledge of who did it does help in some way even if it doesn't take away the grief.
Without the CCTV footage, the police wouldn't have had any leads to work with in the James Bulger case. There is this horrible case in Malaysia right now where CCTV has provided some some clues. There are plenty more cases where CCTV has helped. Maybe you have experienced yourself in your workplace. Something goes missing and you ask around and everyone shrugs their shoulders. But CCTV recording reveals very clearly who dun it!
Don't buy stuff like this or this. Or your money will be going to Japan. I know it's hard to resist and many won't be able to when these are available in November and there'll be a long waiting list for them. I already have a D70 and a D200 but man, I just gotta get my hands on these new babies that were announced today. They'll be available only on November but my money is already starting to burn a hole in my pocket.
If you have full access perhaps you can paste the text here? I'd just like to read the text for now. Don't need the diagrams and pictures, if any. It's a Letter, so it isn't very long.
What did Sony do wrong with the PS3? They pulled out all stops to make it a success but the results have been disappointing. Sony can't be faulted for the superior technology of the PS3 or the huge marketing effort and hype. Or maybe that was the problem: too much technology and hype. After the initial buzz and sales bump, things seem to have gone downhill. And the surprising Wii, the dark horse in the race, with less technology and overshadowed initially by the excitement over the PS3, has now pulled ahead, way ahead. There is a lesson here somewhere.
Slashdot Mirror
Anyways, the reason nobody works on these is probably because our existing antibiotics already work really well, likewise it wouldn't be terribly practical to develop more.
No! No! Bacteria have been evolving antibiotic resistance and things are getting quite desperate, especially in hospital settings. Newer and more potent antibiotics are urgently needed. Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE) and multi-drug-resistant Mycobacterium tuberculosis (MDR-TB) are well-known examples of superbugs. The latest are NDM-1 bacteria that have acquired the ability to defeat carbapenems, the antibiotics of last resort when all else fails. And these are failing too. There is an ongoing arms race between bacteria and antibiotics and it has always been so since the introduction of penicillin. The bacteria are getting ahead and we need new antibiotics since yesterday.
High speed trains are awesome, and they're great for prestige and getting customers to buy that technology. Yet they're out of price range for the majority of customers.
Maybe not? This from a recent World Bank report:
"As of October 1, 2014, over 2.9 billion passengers are estimated to have taken a trip in a China Rail - High Speed train (called CRH services), with traffic growing from 128 million in 2008 to 672 million in 2013, or about 39 percent growth per annum since 2008. In 2013, 530 million of those CRH trips took place on passenger dedicated HSR lines. In 2013, China HSR lines carried slightly more HSR passenger-km (214 billion) than the rest of the world combined. This represented about 2.5 times the HSR passenger-km of Japan, the second largest country in terms of HSR traffic. These are substantial numbers for a system that is still in its early days."
Also, a personal informed opinion here
It's time for having 3 categories. Paid, in-app-purchases, free.
I would add a fourth. Thus the list would be Paid, in-app-purchases, free with ads, FREE. FREE would be really free. Not even ads.
But what about the Fourth Crusade when the Byzantines themselves were attacked and Constantinople - the richest city in Christendom - was sacked, looted and raped by the western Crusaders? It was so awful, shameful and painful that 800 years later Pope John Paul II thought it necessary to apologize for it. There was nothing "good" about that one.
I'm aware of their use of Foxconn from past articles, but how come I don't see Foxconn on the list linked in this article?
Yes, it is. See Hon Hai Precision Industry Co., Ltd. (Foxconn)
That will create the ultimate anti-Apple. Amazon's store is the only one right now that can compete with Apple's App store and if that becomes the de facto Google Android store, that will mean the first real competitor to the iDevice/App Store ecosystem. And Google's cloud + Amazon's cloud will be mother of all clouds too.
I don't have a Science subscription. Nature gives open access to human genome papers but unfortunately Science does not.
Simple query of a well-known statesman. Google gets it right with its very first response. Bing doesn't seem to know what I want. Alpha doesn't have a clue.
Google 1 - Bing 0
Bing and Alpha have a lot of catching up to do. And Google doesn't blink even when I get the spelling wrong as in "Winston Chrchill's Father"
Wrote it.
Shakespeare was the conduit through which Marlowe published his works after he (Marlowe) had to "disappear" through a faked death. Marlowe was a wanted man because of his outspokenness and involvement in the plots and intrigues of the Elizabethan age. The facts about Shakespeare's life that can be determined with absolute certainty make it unlikely that he could be the writer of the great plays, sonnets, and poems that are ascribed to him.
I can't understand why he is doing this. Surely he is rich enough to afford to have noble principles and values and doesn't have to resort to such distasteful methods to enrich himself. And he is also a very smart person. Surely his time and money can be better spent actually implementing useful ideas. Or maybe this is his way of showing how absurd and unfair the current patent system is to goad people into taking action to reform it?
The first author's website has the PDF of the original paper: http://jauy.syr.edu/PUBS/Publications.html
It's the first paper on the list: Difference in plumage color used in species recognition between incipient species is linked to a single amino acid substitution in the melanocortin-1 receptor
And here's the abstract if you don't want to read/download the whole paper:
"Many studies demonstrate that differences in mating signals are used by incipient species in recognizing potential mates or sexual competitors (i.e., species recognition). Little is known, however, about the genetic changes responsible for these differences in mating signals. Populations of the Monarcha castaneiventris flycatcher vary in plumage color across the Solomon Islands, with a subspecies on Makira Island having chestnut bellies and blue-black upper parts (Monarcha castaneiventris megarhynchus) and a subspecies on neighboring satellite islands being entirely blue-black (melanic; Monarcha castaneiventris ugiensis). Here we show that a single nonsynonymous point mutation in the melanocortin-1 receptor (MC1R) gene is present in all melanic birds from one island (Santa Ana) but absent in all chestnut-bellied birds from Makira Island, implicating this mutation in causing melanism. Birds from a second satellite island (Ugi) do not show the same perfect association between this MC1R variant and plumage color, suggesting an alternative mechanism for melanism on this island. Finally, taxidermic mount presentation experiments in Makira (chestnut) and Santa Ana (melanic) suggest that the plumage difference mediates species recognition. Assuming that the signals used in species recognition are also used in mutual mate choice, our results indicate that a single amino acid substitution contributes to speciation."
Yes, we would NEVER let a Catholic decide abortion cases... http://en.wikipedia.org/wiki/John_G._Roberts
Add Alito, Scalia, Kennedy, and Thomas - they are also Catholic and somewhere between very and fairly conservative.
OMG! There goes Roe vs Wade! But seriously, what I meant was right-to-life groups that exist to specifically oppose abortion. Not all Catholics are antiabortion.
I have to admit though that it is a little alarming that the SCOTUS lacks religious diversity.
.. reviewing Roe vs Wade? I don't think that would be allowed to happen.
Can it boot persistently from the SD of my Eee PC 900 and will the wifi just work out of the box? Have never been able to get any of the earlier releases to do these two things.
But better late than never. The Europeans and East Asians are way ahead in high speed rail and it's just such a shame that there hasn't been a single serious attempt at this in the USA. Even as we speak the 819 km Beijing-Shanghai (top speed 220 mph/360 km/h) is being constructed. Wouldn't it be great to have something like that in the USA? It will cost many, many billions but it will be something useful that the nation can be proud of. Unlike wasteful overseas adventures that have caused only pain and shame.
My one concern is that instead of borrowing from the considerable experience of the Europeans and Japanese, time and money will be wasted to reinvent the wheel. High speed rail is a mature technology and it will be best to do what the Chinese have done: bring in and adapt what the Europeans or Japanese already have.
Kind of ironic, isn't it? Linux has long been touted as a Window killer but has instead been a killer of Unix vendors.
And who might that viable third person or party be? Ralph Nader? Ross Perot? And how is he or she going raise the hundreds of millions necessary to get elected without the backing of the RNC and DNC? You are in wishful thinking territory over here. Obama (even if don't like him) was the lesser of two evils in the last election.
You mean like the way Yo-Yo Ma, Itzhak Perlman and friends pretended to play at the Inauguration? Or how Pavarotti lip-synced at the Turin Winter Olympics? Or the way the Sydney Symphony Orchestra pretended to play at the Sydney 2000 Olympics? Where parts of the music that the Sydney Symphony pretended to play was actually prerecorded by the Melbourne Symphony!
So which are the laptops with Broadcom chips? I know my Presario V3000 has but I didn't know that when I bought it. I'll be looking more closely for my next laptop purchase. Is there is up-to-date somewhere that I can check?
Even if CCTVs don't prevent or solve crimes, in many cases they have provided important clues. And closure. If you are parent of a child victim, having some knowledge of who did it does help in some way even if it doesn't take away the grief.
Without the CCTV footage, the police wouldn't have had any leads to work with in the James Bulger case. There is this horrible case in Malaysia right now where CCTV has provided some some clues. There are plenty more cases where CCTV has helped. Maybe you have experienced yourself in your workplace. Something goes missing and you ask around and everyone shrugs their shoulders. But CCTV recording reveals very clearly who dun it!
Don't buy stuff like this or this. Or your money will be going to Japan. I know it's hard to resist and many won't be able to when these are available in November and there'll be a long waiting list for them. I already have a D70 and a D200 but man, I just gotta get my hands on these new babies that were announced today. They'll be available only on November but my money is already starting to burn a hole in my pocket.
If you have full access perhaps you can paste the text here? I'd just like to read the text for now. Don't need the diagrams and pictures, if any. It's a Letter, so it isn't very long.
What did Sony do wrong with the PS3? They pulled out all stops to make it a success but the results have been disappointing. Sony can't be faulted for the superior technology of the PS3 or the huge marketing effort and hype. Or maybe that was the problem: too much technology and hype. After the initial buzz and sales bump, things seem to have gone downhill. And the surprising Wii, the dark horse in the race, with less technology and overshadowed initially by the excitement over the PS3, has now pulled ahead, way ahead. There is a lesson here somewhere.