Sure, after all it is just a different flu. However, the statistics who dies from it suggest that a strong immune system is an extra risk, the deaths are not in the age categories you would expect with a normal flu. But your decision seems to be based on scary stories, and fear is not a good advisor in general and neither is stubbornness. Your call, Darwin may take care of you...
I am a Biologist, please allow me to answer: Yes the DNA or RNA has a function: to make more virus. immune reactions work on anything the immune system recognises, and because the immune system is built with protein, it is mostly protein it recognises. Naked DNA or RNA in the bloodstream is quickly mopped up, so you do not need specific immunity.
Vaccination does not trigger an immediate response if you have never seen the antigen before (and if you have, the vaccination is needless and poses a risk). It takes some time to mount an immune response, about as long as 'the flu' lasts. once this response is established, your immune system 'remembers' it. A next exposure to the antigen will see a much quicker response to the antigen, and the second exposure will also reinforce your long term immunity. Read up on immunity if you still don't trust it, this is basically just how it works.
The flu virus evolves a new shell almost every season, exactly because the immune system reacts on its outer envelope. 'They' have no system to switch between different env genes, as you'd need a lot of overhead for that. Having a lot of mutations between each generation and letting basic evolution take its course works much more efficiently.
Most(all?) viral enveloppes are self assembling and do not need to be hybridised with the vector on a protein level. You just have to make sure your env proteins are expressed trough the vector, so you end up with infected cells bursting with empty shells (as not viral content is produced). You could still have some vector particles in the raw yield, but you need to purify it anyway. Lastly, what negative effects would you expect from an immune reaction to either a plant or insect virus? On the contrary, most vaccines employ adjuvants to make the immune response stronger, so contamination with vector particles would probably not reduce the efficiency of the vaccine.
Ok, if you don't trust technology companies to invest enough in research, then make a tax to ensure they do. If public bodies ('teh gubbermint') cannot do it, and private companies cannot do it, then I wonder how we get any progress at all. relying on a system of state monopolies is very outdated, and very inefficient. The other 50 million was most likely spent on litigation.
Yes, patents are bad as a whole. Patents exercised by public institutions are just a disgrace. There was a one time cost for the research, but there should be a 20-year payback because some standards were based on it? Fair would be dedicating the patent after the costs have been recuperated. Otherwise it becomes gamblimg with public money.
And that is exactly what is wrong with your system. If you can afford a better lawyer that gets you a lower or no sentence, that means you have class justice. Maybe not class as in the classical sense with aristocracy etc, but class as in how much money you can get together (by yourself or your direct environment). Home of the free eh? It seems only if you (or your parents) can afford it. (nearly) 1% of the population behind bars is an awful lot and compares very bad with the rest of the world.
because that 200 million (+ similar amount in attorney fees) could have been spent on research by the ones actually designing and making the devices. add to that the millions of manufacturers that did not fight but decided to pay up. But the bad thing is the methods they used to get their earnings, not the actual subject. patents per-se are bad, so these ones are too. That is is a public institution that does the extortion makes it even worse. Their results should be for the good of all people, or for the good of all australian people if you want to be nationalis.t
Comparing with ridiculous factoids does not prove your argument right. if 200 million is pocket change to you, I'd beg you to give a small part of that to me. In return, I will teach you about the tranquility one obtains by not having to work for your money.
allocating 3/4 of your winnings to science does not diminish the fact that a state-funded organisation has probably spent the remainder on litigation and harassing hi-tech companies. The issuing of patent with a lifetime of 20 years to technology that has a lifetime of much less is stifling progress.
All those commenters that need to make that very funny joke about E.coli => poop. Man, that was funny when you were 6, not 20 or 30 years later. But to go back on topic: This looks a bit like a solution looking for a problem. How much low grade uranium waste is there anyway? Or do they propose to use it in primary uranium mining, to make low uranium content ore usable? Yes there is an unsolved waste problem with uranium fission, but this proposed solution is no solution to that.
What a nice ad-hominem you made there. The midas touch angle makes you look very academic, and the communism jibe shows your colours as a true blue american. Sadly though, there is not a lot of substantial argument behind your ranting (AKA none). You don't like the GPL, but why that is exactly you do not tell. The MIT and or BSD licenses you prefer have been a brake on the uptake/development of all the BSD's. Linux was late to the game of Open Source Unix-like OSes, but it magically overtook all of them by a large margin. That is in part thanks to it's license, that prevented leeches from exploiting the work of contributors. It is those contributors that make Linux what it is, and they like the GPL just fine. You seem to like your precious opinion very much, but luckily that does not make a difference at all. Or should I have not fed the troll?;)
If it is broken down to the molecular level, then it is not so much garbage anymore, but just 'pollution'. Your assumption that there are no larger chunks is absurd too: The plastic has to come from somewhere, it's just that the chances of finding bigger chunks are lower. Personally I have the impression this 'disaster' is being oversold. They are still researching if there is any damage done. How especially does a fishing float pollute the ocean?
Even then there will be (if there are any humans left, that is) a faction that gains from the status quo and has a lot to lose. So eventually there will be red-sun deniers. Oh maybe it will, happen, just not right now. Other then that, the cosmological timescale is meaningless when compared to humans. society has only existed a couple of thousand years, irrelevant when compared to 500 Million years.
Indeed. The list virus has dumbed down at least half of the internet, reviewing a stupid list would take things to an even lower level. Lists suck, write original content.
Yes is does provide selective pressure, just like the immune system does by itself. The pressure is against overexpressing MUC1. Since it is presented as a vaccine, not a therapy, the thinking is that there are no cells yet that overexpress MUC1. Once one does, it will be quickly eliminated. Since it is quick growing cells (like cancer) that mutate at a higher rate, picking off the cells with cancerous signs will reduce this mutation rate, thus hopefully prevent this type of cancer in the lifetime of the (potential) patient. You are right in assuming that the chance of a mutation in patients that already have cancer would be much higher, making it less effective as a treatment. But who knows, maybe it works good enough as a combination therapy?
Right. A revolutionary diet therapy. Someone trying to cure cancer by non-medicinal means. So he is practising medicine without being a doctor? There is a name for that: quack. And people like you that (pretend to) believe in it and preach its blessings are instrumental for mr Gersons paycheck. There is a very good reason alternative medicine is not accepted: it does not work. If you want it to be accepted medically; do the legwork and prove that it works in reproducible double blind tests. If you just want to make a living deceiving other people, you post references on the internets.
The trick is to scam the scammers. Find other 'salespeople' and give them enough hints that this may be a profitable scam. Paying to get in is a subtle trick to get your salespeople more commited (they already have something at stake) and to give them the impression they can really make some serious money with this. Somebody must have done the maths on this after all? (yes, and those people politely decline...)
No, although their beliefs are weird, they are not superstitious. Extra curricular beliefs, not sanctioned by the church are. Regular religious beliefs are just plain stitious, they have nothing to be super of.
For Linux: yes. For android: no. The android OS is significantly different from a 'normal' linux distro. It runs a linux kernel, but the userland looks totally different. Android is java a very long way down, which means you have to rewrite your app. Not just in Java, but to Androids model of doing things.
2 miles would be like a 15 min bike trip or less. But off course, the poster is an 150 kilo slacker that starts to sweat profusely while thinking about exercise, so he just needs a reason not to lift a finger himself...
You can believe anything. So you don't need to make up your own plausible explanation (or better: implausible), you just declare you don't believe that yet, and when some other nutjob has come up with a far-right field explanantion, you start to believe that one, because the guy goes to the same church as you do. In the end, your peer group/tribe is more important thzat reason, especially for unreasonable people. Akkatjoemabh!
Condescending I may be, but your 'shitty job shitty friends, it's not my fault' post gave very little to look up too, IMHO. That projected quite a bad image of you to which I reacted. It is up to you to realize and do something about that. Good luck.
but: if you have bad job, you can change jobs. Slavery has been abolished. The same thing goes for your friends (find/make new ones) or your location. If your full of shit yourself, you perceive everything else as shitty. If you drive away your worthwhile friends because you treat them like shit, you will be left with the ones that treat you like shit too. It is very easy to blame everything on something external, but you will not get ahead with such an attitude. You are an adult (supposedly) so you are the one responsible to take care of yourself, not someone else. If you sit tight and blame the world, very little will change in your world. So in your shitty case: find a good therapist and a good plumber, and just talk about your problems and your feelings. Just that thing alone eases your suffering, and after a while you will find the right thing to do with your life. Like moving to North Dakota.
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Sure, after all it is just a different flu. However, the statistics who dies from it suggest that a strong immune system is an extra risk, the deaths are not in the age categories you would expect with a normal flu.
But your decision seems to be based on scary stories, and fear is not a good advisor in general and neither is stubbornness. Your call, Darwin may take care of you...
No, i did not watch this 'I am legend' thing you talk about. What is it, a painting or something?
I am a Biologist, please allow me to answer:
Yes the DNA or RNA has a function: to make more virus. immune reactions work on anything the immune system recognises, and because the immune system is built with protein, it is mostly protein it recognises. Naked DNA or RNA in the bloodstream is quickly mopped up, so you do not need specific immunity.
Vaccination does not trigger an immediate response if you have never seen the antigen before (and if you have, the vaccination is needless and poses a risk). It takes some time to mount an immune response, about as long as 'the flu' lasts. once this response is established, your immune system 'remembers' it. A next exposure to the antigen will see a much quicker response to the antigen, and the second exposure will also reinforce your long term immunity. Read up on immunity if you still don't trust it, this is basically just how it works.
The flu virus evolves a new shell almost every season, exactly because the immune system reacts on its outer envelope. 'They' have no system to switch between different env genes, as you'd need a lot of overhead for that. Having a lot of mutations between each generation and letting basic evolution take its course works much more efficiently.
Most(all?) viral enveloppes are self assembling and do not need to be hybridised with the vector on a protein level. You just have to make sure your env proteins are expressed trough the vector, so you end up with infected cells bursting with empty shells (as not viral content is produced). You could still have some vector particles in the raw yield, but you need to purify it anyway. Lastly, what negative effects would you expect from an immune reaction to either a plant or insect virus? On the contrary, most vaccines employ adjuvants to make the immune response stronger, so contamination with vector particles would probably not reduce the efficiency of the vaccine.
Ok, if you don't trust technology companies to invest enough in research, then make a tax to ensure they do. If public bodies ('teh gubbermint') cannot do it, and private companies cannot do it, then I wonder how we get any progress at all. relying on a system of state monopolies is very outdated, and very inefficient. The other 50 million was most likely spent on litigation.
Yes, patents are bad as a whole. Patents exercised by public institutions are just a disgrace. There was a one time cost for the research, but there should be a 20-year payback because some standards were based on it? Fair would be dedicating the patent after the costs have been recuperated. Otherwise it becomes gamblimg with public money.
And that is exactly what is wrong with your system. If you can afford a better lawyer that gets you a lower or no sentence, that means you have class justice. Maybe not class as in the classical sense with aristocracy etc, but class as in how much money you can get together (by yourself or your direct environment). Home of the free eh? It seems only if you (or your parents) can afford it. (nearly) 1% of the population behind bars is an awful lot and compares very bad with the rest of the world.
because that 200 million (+ similar amount in attorney fees) could have been spent on research by the ones actually designing and making the devices. add to that the millions of manufacturers that did not fight but decided to pay up. But the bad thing is the methods they used to get their earnings, not the actual subject. patents per-se are bad, so these ones are too. That is is a public institution that does the extortion makes it even worse. Their results should be for the good of all people, or for the good of all australian people if you want to be nationalis.t
Comparing with ridiculous factoids does not prove your argument right. if 200 million is pocket change to you, I'd beg you to give a small part of that to me. In return, I will teach you about the tranquility one obtains by not having to work for your money.
allocating 3/4 of your winnings to science does not diminish the fact that a state-funded organisation has probably spent the remainder on litigation and harassing hi-tech companies. The issuing of patent with a lifetime of 20 years to technology that has a lifetime of much less is stifling progress.
All those commenters that need to make that very funny joke about E.coli => poop. Man, that was funny when you were 6, not 20 or 30 years later.
But to go back on topic: This looks a bit like a solution looking for a problem. How much low grade uranium waste is there anyway? Or do they propose to use it in primary uranium mining, to make low uranium content ore usable?
Yes there is an unsolved waste problem with uranium fission, but this proposed solution is no solution to that.
What a nice ad-hominem you made there. The midas touch angle makes you look very academic, and the communism jibe shows your colours as a true blue american. Sadly though, there is not a lot of substantial argument behind your ranting (AKA none). You don't like the GPL, but why that is exactly you do not tell. ;)
The MIT and or BSD licenses you prefer have been a brake on the uptake/development of all the BSD's. Linux was late to the game of Open Source Unix-like OSes, but it magically overtook all of them by a large margin. That is in part thanks to it's license, that prevented leeches from exploiting the work of contributors. It is those contributors that make Linux what it is, and they like the GPL just fine.
You seem to like your precious opinion very much, but luckily that does not make a difference at all. Or should I have not fed the troll?
If it is broken down to the molecular level, then it is not so much garbage anymore, but just 'pollution'. Your assumption that there are no larger chunks is absurd too: The plastic has to come from somewhere, it's just that the chances of finding bigger chunks are lower. Personally I have the impression this 'disaster' is being oversold. They are still researching if there is any damage done. How especially does a fishing float pollute the ocean?
Even then there will be (if there are any humans left, that is) a faction that gains from the status quo and has a lot to lose. So eventually there will be red-sun deniers. Oh maybe it will, happen, just not right now.
Other then that, the cosmological timescale is meaningless when compared to humans. society has only existed a couple of thousand years, irrelevant when compared to 500 Million years.
Indeed. The list virus has dumbed down at least half of the internet, reviewing a stupid list would take things to an even lower level. Lists suck, write original content.
Yes is does provide selective pressure, just like the immune system does by itself. The pressure is against overexpressing MUC1. Since it is presented as a vaccine, not a therapy, the thinking is that there are no cells yet that overexpress MUC1. Once one does, it will be quickly eliminated. Since it is quick growing cells (like cancer) that mutate at a higher rate, picking off the cells with cancerous signs will reduce this mutation rate, thus hopefully prevent this type of cancer in the lifetime of the (potential) patient.
You are right in assuming that the chance of a mutation in patients that already have cancer would be much higher, making it less effective as a treatment. But who knows, maybe it works good enough as a combination therapy?
Right. A revolutionary diet therapy. Someone trying to cure cancer by non-medicinal means. So he is practising medicine without being a doctor? There is a name for that: quack. And people like you that (pretend to) believe in it and preach its blessings are instrumental for mr Gersons paycheck.
There is a very good reason alternative medicine is not accepted: it does not work. If you want it to be accepted medically; do the legwork and prove that it works in reproducible double blind tests. If you just want to make a living deceiving other people, you post references on the internets.
The trick is to scam the scammers. Find other 'salespeople' and give them enough hints that this may be a profitable scam. Paying to get in is a subtle trick to get your salespeople more commited (they already have something at stake) and to give them the impression they can really make some serious money with this. Somebody must have done the maths on this after all? (yes, and those people politely decline...)
No, although their beliefs are weird, they are not superstitious. Extra curricular beliefs, not sanctioned by the church are. Regular religious beliefs are just plain stitious, they have nothing to be super of.
For Linux: yes. For android: no. The android OS is significantly different from a 'normal' linux distro. It runs a linux kernel, but the userland looks totally different. Android is java a very long way down, which means you have to rewrite your app. Not just in Java, but to Androids model of doing things.
what about the recoil of a shotgun that dumps a load of pellets in you backside?
2 miles would be like a 15 min bike trip or less. But off course, the poster is an 150 kilo slacker that starts to sweat profusely while thinking about exercise, so he just needs a reason not to lift a finger himself...
You can believe anything. So you don't need to make up your own plausible explanation (or better: implausible), you just declare you don't believe that yet, and when some other nutjob has come up with a far-right field explanantion, you start to believe that one, because the guy goes to the same church as you do. In the end, your peer group/tribe is more important thzat reason, especially for unreasonable people.
Akkatjoemabh!
Condescending I may be, but your 'shitty job shitty friends, it's not my fault' post gave very little to look up too, IMHO. That projected quite a bad image of you to which I reacted. It is up to you to realize and do something about that.
Good luck.
but: if you have bad job, you can change jobs. Slavery has been abolished. The same thing goes for your friends (find/make new ones) or your location. If your full of shit yourself, you perceive everything else as shitty. If you drive away your worthwhile friends because you treat them like shit, you will be left with the ones that treat you like shit too.
It is very easy to blame everything on something external, but you will not get ahead with such an attitude. You are an adult (supposedly) so you are the one responsible to take care of yourself, not someone else. If you sit tight and blame the world, very little will change in your world.
So in your shitty case: find a good therapist and a good plumber, and just talk about your problems and your feelings. Just that thing alone eases your suffering, and after a while you will find the right thing to do with your life. Like moving to North Dakota.