"Bioinformatics is the dot-com boom all over again..."
I think not.
There is quite a market for bioinformatics. My employer spends around 5 billion USD a year on pharma R+D. Much of that money is used in traditional "brute-force" type attacks of screening many compounds against many targets.
There is tremendous potential for savings through bioinformatics, and the evidence is working its way through pharma pipelines as we speak.
While there may be as much hype around bioinformatics, the field is solving a genuine problem for a mature, well-funded industry, unlike the dot-com book which speclated on products many didn't want with money that didn't exist.
I have a few tens of thousands of emails filed in around 400 folders in my 550MB Outlook.pst file. (This size is after I strip out almost all attachments!) I manually file them, because Outlook rules are wowefully inadequate.
I keep all these emails because they're some of the most valuable organizational information I can have. I search them daily and would be absoultely lost without them.
What I need is a database that pretends to be an Outlook.pst file. I need to be able to tag files with medadata such as project, business line, and importance, in addition to the standard email headers. I then need folders to exist for each of these categories.
Given that I've had this need since about 1998, I don't understand why Outlook has not yet delivered. (Outlook 97, Outlook 98, Outlook 2000, Outlook XP... how long do we have to wait!?!)
And please kids, don't tell me to use Linux/Pine/Elm/Mutt/whatever. My office email environment is Exchange, and very much makes use of the scheduling system in addition to email, so I'm stuck with it.
The only thought I've had so far is to set up an Outlook rule to forward a copy of every message I get to one of my Linux boxen, where I could chop it up and insert it into a database... but retrieving these messages would require me to use a second interface, and I need the functionality integrated into Outlook.
If only the glass could broadcast location and nightly drinking history. I need the waitress to find me and keep me serving until I've had about ten, then know to tell me to sod off and go home instead of bringing me an eleventh.
(Of course this would be hard to implement across three or four bars/clubs in a night...)
If that's not an Inflammatory headline, I don't know what is.
Besides, who puts CDs in their PCs to listen to them anyway?
(It was rhetorical, but I'll answer anyway: middle aged administrative assistants who won't mind waiting on hold for an hour to complain once they find out that it's the record company's fault their PC crashed. And they will find out. Whichever geek comes to help them will make it known that it's not the PCs fault.)
"World! There are loads of people who have an interest in local interests from other parts of the world."
It's too bad that satellites don't cover more than half a hemisphere at a time. From the US it is just not possible to see the European Astra or Eutelsat constellations. Thus we must pay our satellite companies to rebroadcast to see "the A Team" dubbed in German.:-)
"The biggest change this could have is with advertising dollars. Local vendors would get national coverage - but if a local show suddenly became popular, it could get national dollars."
This is not necessarily true. Satellite companies typically license content and frequently take care of ads themselves, replacing local ads.
I'd say my GPRS does 64k max with latency up to several seconds. That's Cingular Blackberry service in Boston. It's nothing like production quality yet. Maybe in a few years...
I get cold calls at least once a month from headhunters wanting me to do Livelink. I don't list a phone number, email address, or physical address on my online resume; they call information to get to my company and then work their way in from the front desk.
The product is a web based document management system, like Documentum in theory, but much easier to work with in practice. I've been using it since September 01, and it has grown on me.
Users interact via a web site or WebDAV (supposedly works on Linux) to view, add, check in, check out, or delete documents; to interact with workflows; to engage in discussions, and to do whatever else you have your server configured to do.
The web interface allows for use with any operating system, and the java widgets seem to run on our Linux, Sun, OSX, and Irix boxes. (and of course on Windows!) I can't speak for WebDAV, as I haven't used it. I spend a lot of time using their Office integration widgets, which allow me to interact with the repository directly from Windows or MS Office. (More menus appear in your apps.)
I like it because it exports XML over HTTP. I send it a URL and object number, and it sends back a pile of XML that I transform into a web page. It means that I rarely have to update web pages, as I just say a web page is made of objects of type Y, and those objects show up on the web page when a user checks them into the repository.
What's strange is that in the US, it is not too popular. Livelink consultants are impossible to find, and generally bill at around $100/hour. From my colleagues in the UK I understand that the billing is about the same, but that consultants are easier to come by.
It's strange that the product doesn't have much of a name because OpenText has been around since 1991. They're a Canadian company who do about 100 million in sales a year, so they're not small or new.
Anyway, I wasn't impressed up front, but have turned into a fan. And the user response, always important in IT projects, has been extremely positive. Just around 60% of the site's users have requested to participate in training sessions. (Which aren't cheap: Opentext bills $3000/day for onsite training!) And almost every user has been interacting with it daily, with almost no complaints.
So, it's definitely worth considering, especially if you have the money!
Now load your dupe machine once a day for ten days.
Pick up the DVDs when finished and sell them to your dealers for $700/spindle. (they will then be resold at $10-$15/each, a very healthy profit for a street vendor.)
You have just paid for the DVD dupe machine and have made $500. You probably invested twenty hours in buying the hardware, setting it up, testing, and smoking pot with your dealers.
From now on, for every 5 hours you invest in buying and burning another 100 copies, you'll make $450. Not bad, eh?
The getting busted and going to jail part might suck, but you can get around this by doing the duping in a friendly environment. Of course friendly environments sometimes take a little away from the bottom line, but booze is cheaper in those places anyway.
I am seeing smaller binaries as a result of yEnc. This is fine. The problem is, my favorite binaries grabber has no idea what to do with the files, and won't even download them. I figured out how to make Agent download them, but A. I hate Agent (and don't understand why anyone likes it!) and B. the binaries don't always decode.
As I'm a lifetime lurker (well eight years, but it seems a lifetime!) I can only choose not to download yEnc encoded binaries. And no one will know! (my news server doesn't log downloads) It's all up to the posters to adopt or not.
Converter? Can you please post details? I am in love with the 17" Apple panel on my Mac at work, and am about to spend 6k on IBM's 21" panel for my Windows box. If I can use one of the new Apple panels for my PC I'll save a few grand. (though their resolution doesn't equal the IBM's 2048 x 1536)
BTW, the ViewSonic's 1600*1200 resolution doesn't stack up to the apple. That 300*1200 extra pixels is another 20% more resolution.
A long time ago (95-96) I worked at idir.net, an ISP in the midwest. Even back then there were a few a.b.p.e groups we didn't carry, for a time. We had users call and write to complain about us carrying illegal stuff, or not carrying "all the groups." (With no more specificity. We did have a few laughs over those creeps.)
Eventually we consulted our legal counsel, who advised us we had two options. A. meticulously filter our newsgroups and monitor them to make sure illegal things weren't happening, or B. act as a common carrier, and take everything from the mci feed we could subscribe to.
We took the B route, skating around the letter of the law and taking all newsgroups "we knew about" and any others "by written request."
Anyway, what's left of the ISP is now Slurp News. All they do is provide news, w/ a 5TB server and a couple of OC3 pipes.
"You are hereby instructed to immediately, permanently and totally remove any and all information collected in regards to me and any reference to my email address from any and every computer system, on- and off-line storage device or media that you may possess, own, rent or utilize. You are also hereby explicitly notified that you have no permission whatsoever to exchange or propagate any personal information or email address to any "business partners" or other third parties."
Unfortunately for all of us, some things like email addresses are publicly available, and we can't legally prevent someone from maintaining a list of them. (Unless you get in to stalking laws, hit lists, etc.) We can legally insist they do not contact us, but we can't compel them to "take us off the list."
I have every permutation of my home address entered into the DMA do not mail list, I don't have a normal landline telephone, and I use AT&T mail (with their Brightmail filter, which is absolutely amazing) so I generally don't get bothered by spam, except for my hotmail account.
(Yes, I still manually clean 10 spams a day from my hotmail and actively block spam domains (like Virtumundo.com) on this account. But that's it.)
I think you missed the point. Records actually used to be printed on vinyl bound into books/magazines, just as a page. Not an insert, but an actual page. You could tear the vinyl record out of the middle and play it.
This new CD technology would allow this to happen once again.
Have you ever seen a hard disk retail new for under $100?
Some devices have magic price points that won't be broken, even if the devices don't cost much to make. More features will be added, faster processors, better screens, etc, but I think you'll be disappointed in six years.
I actually do remember a guy in the dorms in 1994 who had a P90 that interfered with his FM radio in that range. It's totally realistic, especially if we all start doing silly things like putting our PCs in plexiglass and lucite cases, instead of grounded metal ones.
Blade 100s are absolute dogs. I too have used one, and stay far away. Our DBA installed Oracle 9i on one and the performance was absolutely pathetic - easily bested by the 9i install on his 600 MHz Intel PIII workstation, which he was using for ten other tasks at the same time.
Have a look at their video adverts. They're targeting children. This will be a great toy for kids to plug in to their walkman/discman/mp3 player, and the price is right for their market.
They proved with AS/400 that using a DB for the file system was the way to go. It's too bad they did it way ahead of their time.
I'm personally glad MS is finally changing their OS. Now that my workstation has 70GB of files, searches are taking an incredibly long time.
I have less than 100,000 files on my workstation. Each has maybe 10 searchable attributes. A full search on this can take over five minutes. (Athlon 800Mhz w/ 7200 RPM IBM drives on a Promise controller)
I know from experience that querying an Oracle database (on a cheap 500mhz linux box) on 100,000 records with 30 non-indexed columns/attributes generally takes around 2-3 seconds.
Imagine if MS were able to build a file system with such capabilities.
Consider first the fact that I was working for an ISP when you were still in Jr. High School.
Next, consider that Common Carrier status is first defined in US Code Title 46, Sec. 1702, but is now defined quite differently due to sixty years of legislation and court cases.
Slashdot Mirror
(to diverge ever so slightly)
"Bioinformatics is the dot-com boom all over again..."
I think not.
There is quite a market for bioinformatics. My employer spends around 5 billion USD a year on pharma R+D. Much of that money is used in traditional "brute-force" type attacks of screening many compounds against many targets.
There is tremendous potential for savings through bioinformatics, and the evidence is working its way through pharma pipelines as we speak.
While there may be as much hype around bioinformatics, the field is solving a genuine problem for a mature, well-funded industry, unlike the dot-com book which speclated on products many didn't want with money that didn't exist.
I have a few tens of thousands of emails filed in around 400 folders in my 550MB Outlook .pst file. (This size is after I strip out almost all attachments!) I manually file them, because Outlook rules are wowefully inadequate.
.pst file. I need to be able to tag files with medadata such as project, business line, and importance, in addition to the standard email headers. I then need folders to exist for each of these categories.
I keep all these emails because they're some of the most valuable organizational information I can have. I search them daily and would be absoultely lost without them.
What I need is a database that pretends to be an Outlook
Given that I've had this need since about 1998, I don't understand why Outlook has not yet delivered. (Outlook 97, Outlook 98, Outlook 2000, Outlook XP... how long do we have to wait!?!)
And please kids, don't tell me to use Linux/Pine/Elm/Mutt/whatever. My office email environment is Exchange, and very much makes use of the scheduling system in addition to email, so I'm stuck with it.
The only thought I've had so far is to set up an Outlook rule to forward a copy of every message I get to one of my Linux boxen, where I could chop it up and insert it into a database... but retrieving these messages would require me to use a second interface, and I need the functionality integrated into Outlook.
You must not get out much.
If only the glass could broadcast location and nightly drinking history. I need the waitress to find me and keep me serving until I've had about ten, then know to tell me to sod off and go home instead of bringing me an eleventh.
(Of course this would be hard to implement across three or four bars/clubs in a night...)
If that's not an Inflammatory headline, I don't know what is.
Besides, who puts CDs in their PCs to listen to them anyway?
(It was rhetorical, but I'll answer anyway: middle aged administrative assistants who won't mind waiting on hold for an hour to complain once they find out that it's the record company's fault their PC crashed. And they will find out. Whichever geek comes to help them will make it known that it's not the PCs fault.)
"World! There are loads of people who have an interest in local interests from other parts of the world."
:-)
It's too bad that satellites don't cover more than half a hemisphere at a time. From the US it is just not possible to see the European Astra or Eutelsat constellations. Thus we must pay our satellite companies to rebroadcast to see "the A Team" dubbed in German.
"The biggest change this could have is with advertising dollars. Local vendors would get national coverage - but if a local show suddenly became popular, it could get national dollars."
This is not necessarily true. Satellite companies typically license content and frequently take care of ads themselves, replacing local ads.
I'd say my GPRS does 64k max with latency up to several seconds. That's Cingular Blackberry service in Boston. It's nothing like production quality yet. Maybe in a few years...
I get cold calls at least once a month from headhunters wanting me to do Livelink. I don't list a phone number, email address, or physical address on my online resume; they call information to get to my company and then work their way in from the front desk.
The product is a web based document management system, like Documentum in theory, but much easier to work with in practice. I've been using it since September 01, and it has grown on me.
Users interact via a web site or WebDAV (supposedly works on Linux) to view, add, check in, check out, or delete documents; to interact with workflows; to engage in discussions, and to do whatever else you have your server configured to do.
The web interface allows for use with any operating system, and the java widgets seem to run on our Linux, Sun, OSX, and Irix boxes. (and of course on Windows!) I can't speak for WebDAV, as I haven't used it. I spend a lot of time using their Office integration widgets, which allow me to interact with the repository directly from Windows or MS Office. (More menus appear in your apps.)
I like it because it exports XML over HTTP. I send it a URL and object number, and it sends back a pile of XML that I transform into a web page. It means that I rarely have to update web pages, as I just say a web page is made of objects of type Y, and those objects show up on the web page when a user checks them into the repository.
What's strange is that in the US, it is not too popular. Livelink consultants are impossible to find, and generally bill at around $100/hour. From my colleagues in the UK I understand that the billing is about the same, but that consultants are easier to come by.
It's strange that the product doesn't have much of a name because OpenText has been around since 1991. They're a Canadian company who do about 100 million in sales a year, so they're not small or new.
Anyway, I wasn't impressed up front, but have turned into a fan. And the user response, always important in IT projects, has been extremely positive. Just around 60% of the site's users have requested to participate in training sessions. (Which aren't cheap: Opentext bills $3000/day for onsite training!) And almost every user has been interacting with it daily, with almost no complaints.
So, it's definitely worth considering, especially if you have the money!
(not that I recommend going in to this business...)
3 26050 for $4k. Buy one.
v 47gb.html for $250. Buy ten of them.
In traditional Slashdot fashion, I will now pull some prices out of my ass (sorry, that would be the Internet) and will "do the math."
The entry cost is not high. Less than $7k to profit.
Here's a DVD dupe machine with a 100-disc hopper: http://www.cdw.com/shop/products/default.asp?EDC=
Here's a spindle of 100 DVDs http://shop.store.yahoo.com/spectraimpex1/100pacd
Now load your dupe machine once a day for ten days.
Pick up the DVDs when finished and sell them to your dealers for $700/spindle. (they will then be resold at $10-$15/each, a very healthy profit for a street vendor.)
You have just paid for the DVD dupe machine and have made $500. You probably invested twenty hours in buying the hardware, setting it up, testing, and smoking pot with your dealers.
From now on, for every 5 hours you invest in buying and burning another 100 copies, you'll make $450. Not bad, eh?
The getting busted and going to jail part might suck, but you can get around this by doing the duping in a friendly environment. Of course friendly environments sometimes take a little away from the bottom line, but booze is cheaper in those places anyway.
Cheers,
JB
I am seeing smaller binaries as a result of yEnc. This is fine. The problem is, my favorite binaries grabber has no idea what to do with the files, and won't even download them. I figured out how to make Agent download them, but A. I hate Agent (and don't understand why anyone likes it!) and B. the binaries don't always decode.
As I'm a lifetime lurker (well eight years, but it seems a lifetime!) I can only choose not to download yEnc encoded binaries. And no one will know! (my news server doesn't log downloads) It's all up to the posters to adopt or not.
I may have missed something, but where is the connection between the 3 year old New York Times article and building a UFO?
Converter? Can you please post details? I am in love with the 17" Apple panel on my Mac at work, and am about to spend 6k on IBM's 21" panel for my Windows box. If I can use one of the new Apple panels for my PC I'll save a few grand. (though their resolution doesn't equal the IBM's 2048 x 1536)
BTW, the ViewSonic's 1600*1200 resolution doesn't stack up to the apple. That 300*1200 extra pixels is another 20% more resolution.
I can give you a different spin on this.
A long time ago (95-96) I worked at idir.net, an ISP in the midwest. Even back then there were a few a.b.p.e groups we didn't carry, for a time. We had users call and write to complain about us carrying illegal stuff, or not carrying "all the groups." (With no more specificity. We did have a few laughs over those creeps.)
Eventually we consulted our legal counsel, who advised us we had two options. A. meticulously filter our newsgroups and monitor them to make sure illegal things weren't happening, or B. act as a common carrier, and take everything from the mci feed we could subscribe to.
We took the B route, skating around the letter of the law and taking all newsgroups "we knew about" and any others "by written request."
Anyway, what's left of the ISP is now Slurp News. All they do is provide news, w/ a 5TB server and a couple of OC3 pipes.
They are atypical in that they use their own SMTP servers. (virtumundo.com and virtumundo.net)
"You are hereby instructed to immediately, permanently and totally remove any and all information collected in regards to me and any reference to my email address from any and every computer system, on- and off-line storage device or media that you may possess, own, rent or utilize. You are also hereby explicitly notified that you have no permission whatsoever to exchange or propagate any personal information or email address to any "business partners" or other third parties."
Unfortunately for all of us, some things like email addresses are publicly available, and we can't legally prevent someone from maintaining a list of them. (Unless you get in to stalking laws, hit lists, etc.) We can legally insist they do not contact us, but we can't compel them to "take us off the list."
I have every permutation of my home address entered into the DMA do not mail list, I don't have a normal landline telephone, and I use AT&T mail (with their Brightmail filter, which is absolutely amazing) so I generally don't get bothered by spam, except for my hotmail account.
(Yes, I still manually clean 10 spams a day from my hotmail and actively block spam domains (like Virtumundo.com) on this account. But that's it.)
What's his IP range, or who's his upstream provider?
I always thought porn came from Usenet. Any other way about it seems pretty daft to me.
I think you missed the point. Records actually used to be printed on vinyl bound into books/magazines, just as a page. Not an insert, but an actual page. You could tear the vinyl record out of the middle and play it.
This new CD technology would allow this to happen once again.
Have you ever seen a hard disk retail new for under $100?
Some devices have magic price points that won't be broken, even if the devices don't cost much to make. More features will be added, faster processors, better screens, etc, but I think you'll be disappointed in six years.
I actually do remember a guy in the dorms in 1994 who had a P90 that interfered with his FM radio in that range. It's totally realistic, especially if we all start doing silly things like putting our PCs in plexiglass and lucite cases, instead of grounded metal ones.
Blade 100s are absolute dogs. I too have used one, and stay far away. Our DBA installed Oracle 9i on one and the performance was absolutely pathetic - easily bested by the 9i install on his 600 MHz Intel PIII workstation, which he was using for ten other tasks at the same time.
I know you mean to be funny, but I wouldn't want people to believe you.
There's video footage of her online here:
http://www.cbc.ca/cyberman/video/betty.ram
She looks pretty normal to me.
Have a look at their video adverts. They're targeting children. This will be a great toy for kids to plug in to their walkman/discman/mp3 player, and the price is right for their market.
They proved with AS/400 that using a DB for the file system was the way to go. It's too bad they did it way ahead of their time.
I'm personally glad MS is finally changing their OS. Now that my workstation has 70GB of files, searches are taking an incredibly long time.
I have less than 100,000 files on my workstation. Each has maybe 10 searchable attributes. A full search on this can take over five minutes. (Athlon 800Mhz w/ 7200 RPM IBM drives on a Promise controller)
I know from experience that querying an Oracle database (on a cheap 500mhz linux box) on 100,000 records with 30 non-indexed columns/attributes generally takes around 2-3 seconds.
Imagine if MS were able to build a file system with such capabilities.
Consider first the fact that I was working for an ISP when you were still in Jr. High School.
Next, consider that Common Carrier status is first defined in US Code Title 46, Sec. 1702, but is now defined quite differently due to sixty years of legislation and court cases.
Finally, consider fucking yourself.
Thank You.