aS A Drunk biochemist i'll lend my thoughts...
on
Speeding up Evolution
·
· Score: 5, Interesting
ok Ill bite. Disecting the article: Only a few daredevils, for example, would risk surgery to upgrade their vision from normal to extraordinary. This is mostly because the surgery (lasic) has a potential to go horribly wrong and doesn't give much better than 20/20.
Athletes, enticed by fat contracts, Olympic medals, and fan adulation, will accept almost any health risk to steal an advantage.
yes. Believe it or not a survey of athletes I read, said that 90+% would take *any* drug to improve their performance with or without serious side-effects. The key was *not getting caught*.
Steroids and nutritional supplements-certified by home-run records and 350-pound offensive linemen-have already found their way to every major high-school sports program in the United States.
This is true. But the *only* supplement that has been shown in real clinical trials to work is creatine. ALL THE OTHERS ARE BOGUS. And steroids REALLY work. But their side-effects are really fucking bad.
Anyone who injects steroids can get very strong, but only if he lifts weights regularly
You don't *necessarily* have to lift weights for steroids to build muscle, but it helps a lot.
In recent years, doctors have been virtually dragging seniors to the weight room to get them buffed up.
Yes, this is because the benefit is FUCKING ENOURMOUS. take this to heart old people reading/.
The IGF gene is a multitasker.
Bad analogy. What they're trying to get at is that IGF genes turn on many other responses both at the genetic level and other. It turns on other genes and interacts with many pathways. It's a controler gene.
Both MGF and IGF-1 encourage muscles to grow.
Yeah. just watch out for the shitty side effects.. like CANCER.
Goldspink hopes MGF could be a therapy for the sick and frail
Yes, here's the deal... Frail people, the elderly, those who are lacking in what these genes provide are the ones who will recieve the biggest benefit with the least side-effects. This is important.
The technique for inserting the gene into muscles is not complicated
Yes it bloody well is. don't lie. Right now, it's bloody complicated.
Although Goldspink's experiment resulted in Schwarzenegger mice, that doesn't mean that MGF will successfully pump up normal humans
Theres a bloody good chance of it tho. I'd lay money on it.
And as for IGF-1, it may have health risks that MGF does not
ok, let's make this clear. Don't take IGF-1. It DOES cause a lot of death-leading problems. heart failure AND cancer are just 2 of them.
Athletes are already experimenting with IGF-1
This HAS lead to deaths. It doesn't appear from the research that taking IGF-1 is safe at any level. But human trials are not done because we have laws in the U.S. against killing people for the sake of research.
On EPO:
Here is the trade-off. More bloodcells = slightly better performance & slightly increased risk of clogging your arteries. My opinion is nature worked out the proper ratio.
In fact, if you exercise regularly you will be amazed at how much you are rewarded.
You can start fucking around with your body. It can produce very large effects. But you're fucking with millions of years of evolution. You better have a good reason. There *might* be situations where it's beneficial. For example, humans evolved to fit an environment where food was a little more scarce than nowadays. That's why people are overweight. Evolution didn't get it wrong.. we changed the rules. But for a HECK of a lot of other things, evolution has found the perfect balance... don't fuck with millions of years of trial & error. That's all I have to say. Yes, if you have a genetic disease, then you're merely correcting the "error" part of "trial & error". Don't forget that without the error part there's no trial part and no improvement..
Look I'm really sorry if I've just laid drunken post on you guys.
I just felt like saying something because I happen to be a few things. A/. & gnu/Linux geek, a biochemist and a bodybuilder.
I felt like opining. Some of my opinions are based on research I've read for classes. Other parts are just speculation.
The thing controls the laser beam by bouncing it around mirrors inside the aircraft.
What if the missiles were covered in mirrors themselves? Wouldn't that completely negate the effect of this thing?
I have to admit that would be really funny.
Agreed.
Hire a good sysadmin and the job will get done much better and faster.
Itanium also doesn't sound like the way to go for you.
Think about it. Hammer is going to be out in a few weeks which will give you better 64-bit & 32-bit performance than the itanium for a fraction of the price. It's not the solution for everyone, but for you.. it sounds like it.
Now about redhat... You could consider other distros as well like Gentoo which give you added benefits like better package management especially if you are going to have a lot of your own source around. You can write ebuilds for them and easily install your source packages on all your machines. It could also give you a nice performance benefit.
But the distro might best be picked by the sysadmin you hire. (who needs to be a specialist in linux, but maybe not already tied down to a specific distribution)
you know, the opt's are not the biggest benefit of gentoo.
I find that it's building every package with the options you want.
want to enable kde support. USE='kde'
want no cups support USE="-cups".
Not only this, but it also ends up that you never have dependency problems because each app/lib etc is BUILT for your system.
I thought he was including linux in when he said "unix is dead".
I guess not.
Well, I wonder if he's *ever heard* of freebsd or openbsd or netbsd. They are real unix. They won't easily die for a long time.
"No, they didn't listen to bashers. They listened to the usability tests that Sun and Ximian have done, with user skills from beginners to those very experienced with UNIX."
Yeah, and therein lies their problem. For all the money that goes into usability testing, they are BULL-FUCKING-SHIT.
No offense, but they sit these people who've never used gnome before in front of a computer for 15 minutes. Watch them go: duh.. I don't get it. and then try to draw conclusions based on this as to what would make gnome better for everyone.
What utter fuckin bullshit. Do you buy a computer, use the desktop environment for 15 minutes, and then throw it away because you're done? NO! You use your computer for at least 3-4 YEARS. You learn. You're not a computer-illiterate-monkey for the rest of your life with a goldfish memory. In other words, of ALL the people using gnome *right now* only about 2 of em are within the first 15 minutes of using it. All the rest are at different stages of being used to it. Therefore the whole basis of these usability studies is that they're great for making gnome usable the first 15 minutes you sit down with it.. but that's it. Then you're out of the target market that benefits from them.
You want to do R-E-A-L usability studies? get 100+ people who use gnome NOW. Of all different levels of skills, just like distributed in the user community. Study them for at least 3 months. Thouroughly. Then make your decisions.
wish to try it and report bugs, you won't regret it. In my experience they tend to have the fastest turn around I've ever seen fixing bugs. All of mine were fixed within 24hrs of reporting.
that's the thing about mandrake. It was never too dumbed down at all. I had to use mandrake as a rescue system last week and i was really overjoyed by how quick and easy it was to install a base system and from the cli, urpmi all the rescue packages I needed and use them.
what would be interesting to find out, is if some enterprizing young lad who read this paper, decided to go ahead and fix the bugs which caused the 1% fail in the gnu tools just because it was FS and he could. I would like to see the results of the same tests run again today:)
The website is called cantrip corpus. One of the definitions of cantrip is: an elaborate deception or prank.
Either way I don't see this as an interesting piece. The reporter plays it stupid and tries to get Gates angry so he will say a bunch of stupid and incoherent shit.
You know the strip on the back that says signature? Don't sign it. Write.
that way when someone uses your card in a store they have to also produce your drivers license with holograms and photo and of course the signature they're supposed to be checking:)
Hey it's not much but if someone steals my wallet, my credit card is useless to them before i cancel it.
well, then there's the fact that these software licenses are overly-complicated. And that the great majority of people who buy software from BSA supporting companies have absolutely no f'ing clue of what they just agreed to...
In other words, their buisness is dependant on the fact that the huge majority of people they do buisness with, don't know what the terms of the contract is.
How in the world are you going to talk about the safety of msg by linking to a chinese cuisine page
and saying they have credible information? Check out this CHOICE quote from their scientific information on how MSG works:
It has long been known that there are four basic tastes - sweet, sour, salty, and bitter. It is now thought that there is a fifth taste, called "umami."
What utter crock. next time, please link the FDA directly instead of quoting these guys thanks.
does the patent office even check if the submissals actually exist/work whatever as claimed?
or do they just pay 10,000 monkeys to read through it then rubber stamp it?
I read the whole article and I don't see anything that mentions how these patents are actually checked/verified.
just says they're getting 'stricter'. Well boo-hoo. Before they just rubberstamped any shite that came thru, and now you have to tell them a little bit about the shite before they rubberstamp it without checking.
Slashdot Mirror
Only a few daredevils, for example, would risk surgery to upgrade their vision from normal to extraordinary.
This is mostly because the surgery (lasic) has a potential to go horribly wrong and doesn't give much better than 20/20.
Athletes, enticed by fat contracts, Olympic medals, and fan adulation, will accept almost any health risk to steal an advantage.
yes. Believe it or not a survey of athletes I read, said that 90+% would take *any* drug to improve their performance with or without serious side-effects. The key was *not getting caught*.
Steroids and nutritional supplements-certified by home-run records and 350-pound offensive linemen-have already found their way to every major high-school sports program in the United States.
This is true. But the *only* supplement that has been shown in real clinical trials to work is creatine. ALL THE OTHERS ARE BOGUS. And steroids REALLY work. But their side-effects are really fucking bad.
Anyone who injects steroids can get very strong, but only if he lifts weights regularly
You don't *necessarily* have to lift weights for steroids to build muscle, but it helps a lot.
In recent years, doctors have been virtually dragging seniors to the weight room to get them buffed up. /.
Yes, this is because the benefit is FUCKING ENOURMOUS. take this to heart old people reading
The IGF gene is a multitasker.
Bad analogy. What they're trying to get at is that IGF genes turn on many other responses both at the genetic level and other. It turns on other genes and interacts with many pathways. It's a controler gene.
Both MGF and IGF-1 encourage muscles to grow. Yeah. just watch out for the shitty side effects.. like CANCER.
Goldspink hopes MGF could be a therapy for the sick and frail
Yes, here's the deal... Frail people, the elderly, those who are lacking in what these genes provide are the ones who will recieve the biggest benefit with the least side-effects. This is important.
The technique for inserting the gene into muscles is not complicated
Yes it bloody well is. don't lie. Right now, it's bloody complicated.
Although Goldspink's experiment resulted in Schwarzenegger mice, that doesn't mean that MGF will successfully pump up normal humans
Theres a bloody good chance of it tho. I'd lay money on it.
And as for IGF-1, it may have health risks that MGF does not
ok, let's make this clear. Don't take IGF-1. It DOES cause a lot of death-leading problems. heart failure AND cancer are just 2 of them.
Athletes are already experimenting with IGF-1
This HAS lead to deaths. It doesn't appear from the research that taking IGF-1 is safe at any level. But human trials are not done because we have laws in the U.S. against killing people for the sake of research.
On EPO:
Here is the trade-off. More bloodcells = slightly better performance & slightly increased risk of clogging your arteries. My opinion is nature worked out the proper ratio.
In fact, if you exercise regularly you will be amazed at how much you are rewarded.
You can start fucking around with your body. It can produce very large effects. But you're fucking with millions of years of evolution. You better have a good reason. There *might* be situations where it's beneficial. For example, humans evolved to fit an environment where food was a little more scarce than nowadays. That's why people are overweight. Evolution didn't get it wrong.. we changed the rules. But for a HECK of a lot of other things, evolution has found the perfect balance... don't fuck with millions of years of trial & error. That's all I have to say. Yes, if you have a genetic disease, then you're merely correcting the "error" part of "trial & error". Don't forget that without the error part there's no trial part and no improvement..
Look I'm really sorry if I've just laid drunken post on you guys. /. & gnu/Linux geek, a biochemist and a bodybuilder.
I just felt like saying something because I happen to be a few things. A
I felt like opining. Some of my opinions are based on research I've read for classes. Other parts are just speculation.
The thing controls the laser beam by bouncing it around mirrors inside the aircraft.
What if the missiles were covered in mirrors themselves? Wouldn't that completely negate the effect of this thing?
I have to admit that would be really funny.
Agreed.
Hire a good sysadmin and the job will get done much better and faster.
Itanium also doesn't sound like the way to go for you.
Think about it. Hammer is going to be out in a few weeks which will give you better 64-bit & 32-bit performance than the itanium for a fraction of the price. It's not the solution for everyone, but for you.. it sounds like it.
Now about redhat... You could consider other distros as well like Gentoo which give you added benefits like better package management especially if you are going to have a lot of your own source around. You can write ebuilds for them and easily install your source packages on all your machines. It could also give you a nice performance benefit.
But the distro might best be picked by the sysadmin you hire. (who needs to be a specialist in linux, but maybe not already tied down to a specific distribution)
shit my bad. What i meant to say is the biggest benefit of gentoo is that it's SO FUCKIN EASY to write ebuilds and add new software to the distro.
want to enable kde support. USE='kde' want no cups support USE="-cups". Not only this, but it also ends up that you never have dependency problems because each app/lib etc is BUILT for your system.
Minitab through wine.
I thought he was including linux in when he said "unix is dead".
I guess not.
Well, I wonder if he's *ever heard* of freebsd or openbsd or netbsd. They are real unix. They won't easily die for a long time.
Shows how much you know. Knoppix is named after it's creator Klaus Knopper.
Yeah, and therein lies their problem. For all the money that goes into usability testing, they are BULL-FUCKING-SHIT.
No offense, but they sit these people who've never used gnome before in front of a computer for 15 minutes. Watch them go: duh.. I don't get it.
and then try to draw conclusions based on this as to what would make gnome better for everyone.
What utter fuckin bullshit. Do you buy a computer, use the desktop environment for 15 minutes, and then throw it away because you're done? NO! You use your computer for at least 3-4 YEARS. You learn. You're not a computer-illiterate-monkey for the rest of your life with a goldfish memory. In other words, of ALL the people using gnome *right now* only about 2 of em are within the first 15 minutes of using it. All the rest are at different stages of being used to it. Therefore the whole basis of these usability studies is that they're great for making gnome usable the first 15 minutes you sit down with it.. but that's it. Then you're out of the target market that benefits from them.
You want to do R-E-A-L usability studies? get 100+ people who use gnome NOW. Of all different levels of skills, just like distributed in the user community. Study them for at least 3 months. Thouroughly. Then make your decisions.
wish to try it and report bugs, you won't regret it. In my experience they tend to have the fastest turn around I've ever seen fixing bugs. All of mine were fixed within 24hrs of reporting.
that's the thing about mandrake. It was never too dumbed down at all. I had to use mandrake as a rescue system last week and i was really overjoyed by how quick and easy it was to install a base system and from the cli, urpmi all the rescue packages I needed and use them.
what would be interesting to find out, is if some enterprizing young lad who read this paper, decided to go ahead and fix the bugs which caused the 1% fail in the gnu tools just because it was FS and he could. I would like to see the results of the same tests run again today :)
Either way I don't see this as an interesting piece. The reporter plays it stupid and tries to get Gates angry so he will say a bunch of stupid and incoherent shit.
It should read ..."Write CHECK ID on it."
that way when someone uses your card in a store they have to also produce your drivers license with holograms and photo and of course the signature they're supposed to be checking :)
Hey it's not much but if someone steals my wallet, my credit card is useless to them before i cancel it.
When all you have is a hammer...
Everything starts to look like nails >:)
When all you have is a hammer.. everything starts to look like nails >:)
They even steal the food from the mouths of the little babies of kde workers!
It was umass amherst wasn't it?
In other words, their buisness is dependant on the fact that the huge majority of people they do buisness with, don't know what the terms of the contract is.
Nice way to do buisness. Very nice.
as far as i recall, you only have to pay trolltech once to be able to develop apps with QT.
which is HERE by the way.
I just have to point this out...
How in the world are you going to talk about the safety of msg by linking to a chinese cuisine page
and saying they have credible information? Check out this CHOICE quote from their scientific information on how MSG works:It has long been known that there are four basic tastes - sweet, sour, salty, and bitter. It is now thought that there is a fifth taste, called "umami."
What utter crock. next time, please link the FDA directly instead of quoting these guys thanks.
or do they just pay 10,000 monkeys to read through it then rubber stamp it?
I read the whole article and I don't see anything that mentions how these patents are actually checked/verified.
just says they're getting 'stricter'. Well boo-hoo. Before they just rubberstamped any shite that came thru, and now you have to tell them a little bit about the shite before they rubberstamp it without checking.
because I'm really curious what they will say.