Did any read the summary? AT&T said google can use the poles, you just have to be a cable provider or telecom like everyone else that uses the poles. That seems fair to me. Come on Google go buy another company and run some wires!
Is VOIP + 911 service enough to get you qualified as a telecom provider? AT&T might regret asking Google to undercut them on phone service...
I just picked up a Nook HD for my mom for $80. The Nook skin for Android is pretty simple, the 7" platform is light enough to hold up when reading ebooks, and the display is still good enough for movies/great for reading books. The only trick is to watch flash video you need to add a browser like Puffin.
Don't confuse appetite inhibitors with stimulants please, almost no doctor in his/her right mind would prescribe stimulants to obese people (they'd just eat more to compensate),
Phentermine is a stimulant with effects similar to amphetamines. It is still prescribed for weight loss both on its own (suprenza) and in combination with other drugs (Qsymia).
Interestingly you can take 400mg a day of topiramate for neurological conditions without a warning, but if you take 23mg a day for weight loss you have to be warned of the risk. Not that there is a bias against obesity or anything...
They added a warning about topamax/topiramate and pregnancy a little while ago, but it's the "benefits may exceed the risks" type warning, not a black boxed warning. If you're taking a topiramate containing drug to lose weight I'd guess they would say to just skip it for 9 months.
TOPAMAX® (topiramate) can cause fetal harm when administered to a pregnant woman. Data from pregnancy registries indicate that infants exposed to topiramate in utero have an increased risk for cleft lip and/or cleft palate (oral clefts). When multiple species of pregnant animals received topiramate at clinically relevant doses, structural malformations, including craniofacial defects, and reduced fetal weights occurred in offspring. TOPAMAX® should be used during pregnancy only if the potential benefit outweighs the potential risk. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to a fetus.
A big problem with keeping weight off is it takes a long time for your body to adjust to the new normal. Losing 10% of your bodyweight can adjust the levels of appetite-related hormones so that they resemble those of someone who is truly starving, and they can stay like that for 6 months or more. Basal metabolism is also decreased after weight loss, so that for someone to maintain their new weight they have to eat less than a twin of that same weight/activity level who hadn't recently lost weight. A drug that helps you maintain weight loss during that adjustment period might get a lot of people over the hump, at which point they could quit taking the drug.
Telling people stuff is fine, but once you charge for the service you open yourself up to regulation. For years I've thought that the direct-to-consumer genetic testing industry would end up split into companies that charged to sequence your DNA on the one hand and free software that interpreted the data on the other. Originally I thought this would be the way to avoid infringing the thousands of patents on DNA tests a paid service would run afoul of, but now that DNA patents have been sharply limited I think this shift might still happen in order to escape FDA problems.
Actually if the research involves human subjects and is intended to support a product that would require FDA approval an IRB is required even if the funding is all private. The FDA has rules about how IRBs must be formed, but I dont' think they certify them. 23andMe and the companies it sells data/research services to might be exempt though since they could claim the data wasn't collected for any particular study: the data just happened to be available after customers plonked down their $99.
Those are the results of individual FDA approved genetic tests.
A "secondary market" for running thousands of tests at once would run into the same problem that 23andMe did: if you are going to sell diagnostic services in the USA then you will need to get FDA approval. The options are to only provide raw data and let someone else generate the report for free (see Promethease, mentioned below) or move the whole company someplace where law enforcement won't bother it. I could see 23andMe spinning off an independent foundation that would generate free reports, thus allowing their core business (building up a database of peoples DNA and personal/family medical histories that they can rent out for medical research free from the normal regulatory hurdles) to proceed unhindered. They would just have to be very careful to make certain there was no linkage between the for profit and the free companies: the non-profit would have to generate reports from data of any source, not just SNPs from 23andMe, it couldn't share any board members or employees with 23andMe, Google, etc.
Next legal challenge for 23andMe: doing medical research on people (gathering their DNA and medical histories, analyzing, allowing 3rd parties to analyze, etc) without getting IRB approvals first.
Anyone know how music licensing compares to television licensing? Is it a matter of per play/acquiring monthly rights?
The main difference: TV and movie content owners are extremely selective about who they will license streaming rights to, at least for content that still has a high demand. They want the streaming platform they are affiliated with to succeed and the ones they aren't affiliated with to fail. On that note: the new head of the FCC just said he thinks it would be fine for ISPs to start charging Netflix extra, giving their own streaming solutions a competitive advantage.
You're forgetting why bands sign to labels to begin with: Advertising.
The record labels are the ones that can (and do) do the legwork to set up and promote concerts,
Which is now done by the band themselves on social media.
That leaves out the dominant form of advertising: payola. Major labels spend a lot to get songs on the radio, whether it's laundered through "independent promoters" or just cutting checks to Clear Channel. Then there's TV/Movies: the major labels are all affiliated with TV/movie studios, so the songs played on every teen-centric show are pretty strategically chosen.
For someone that already has XP, the cost has already been paid and there is no future cost. If you try to force such a user to upgrade they will quite understandably object.
Especially if the cost that has already been paid is zero. in 2011 Ballmer claimed 90% of Chinese copies of Windows were pirated.
I think the concerns over there are:
1. Exploits on unsupported copies of XP would be a drag on the economy.
2. Actually paying for Microsoft software would be a drag on the economy.
To solve the issue China should just buy Microsoft. Two birds with one stone: They could pay for Microsoft in US T-bills and then make China-specific versions of Windows based products and sell them at cost. Bonus: Microsoft products could behave... oddly when installed in Taiwan.
RF Safe-Stop Shuts Down Car Engines With Radio Pulse
As the vehicle entered the range of the RF Safe-stop, its dashboard warning lights and dials behaved erratically, the engine stopped and the car rolled gently to a halt. Digital audio and video recording devices in the vehicle were also affected.''It's a small radar transmitter,' said Andy Wood, product manager for the machine. 'The RF [radio frequency] is pulsed from the unit just as it would be in radar, it couples into the wiring in the car and that disrupts and confuses the electronics in the car causing the engine to stall.'"
Hiring someone to pick it up once a week is certainly cheaper, but for an apartment complex that means the yard is full of poop 6 1/2 days out of seven.
Some friends of mine who have 5 dogs (the wife is a vet and ends up with a lot of rescues) redid their back yard with St. Augustine back in the spring. It's still looking great.
Cats are definitely for people who want a family relationship - with an angsty teenager. On a more serious note dogs do require a lot more responsibility and a lot more socialization; they are prone to behavioral disorders if they don't get it. I wish people who have no free time/spend little time at home would think about that before buying the cute puppy.
When industrial 3D printers can print sets of legos 1, at the same tolerance (10 micron) as legos made from a mold, 2, cheaper than wholesale legos made from a mold you'll definitely have a point. Until then I think we'll see a much bigger impact from using 3D printing to make molds, prototypes, and one offs than from making actual consumer items. And I know the argument is that people will have a printer at home or use a printing service, thus cutting costs by getting rid of a long chain of transport and middle men. But people don't actually spend much on things that are purely 3D printable, and when things break it's usually not just a user-replaceable 3D printable plastic part at fault.
Hmmm...Time to take a weather balloon and a big sheet of aluminized mylar on a frame and let them out right in the line of sight and do something that makes money when their communications slow down.
Like charging $10k per minute to not drop microwave chaff in their line of sight? I like it.
What does China do again? Provide cheap labor? 3D printing will eliminate that advantage.
China Provides cheap labor, lax environmental and zoning restrictions, entire cities organized around particular industries... 3D printing is a very expensive and very slow way to manufacture pieces of plastic or metal in small quantities. If it was a fast and inexpensive way to make things by the gross they would make things that way in China. Instead they make 3D printers (stepper motors, motor drivers, microcontrollers, wires and connectors, etc) and sell them to us.
Just accumulate all of the orders for one second. At the end of each second match the closest buy/sell orders to each other and execute the trades. Repeat.
The advantage of (real) Supercomputers is that they can tackle large scale simulations (instead of large numbers of small scale simulations, which is what "Folding@Home" and co. do). Would the quality of the predictions go up if they used a more accurate (and thus computationally complex) model of the forcefield?
It would certainly help when it comes to electrostatics: solving the full nonlinear Poisson Boltzmann equation (as opposed to approximations) for all the atoms in the solvent, protein, and drug molecules is a bitch; doing it several billion times during a simulation is... bitch x 10^9. The problem right now is that predictions from first principles of much simpler systems still tend to get a lot of things wrong: they're really only beginning to get a handle on how water works at this scale.
The advantage of (real) Supercomputers is that they can tackle large scale simulations (instead of large numbers of small scale simulations, which is what "Folding@Home" and co. do). Would the quality of the predictions go up if they used a more accurate (and thus computationally complex) model of the forcefield?
It would certainly help when it comes to electrostatics: solving the full nonlinear Poisson Boltzmann equation (as opposed to approximations) for all the atoms in the solvent, protein, and drug molecules is a bitch; doing it several billion times during a simulation is... bitch x 10^9. The problem right now is that predictions from first principles of much simpler systems still tend to get a lot of things wrong: they're really only beginning to get a handle on how water works at this scale.
Did any read the summary? AT&T said google can use the poles, you just have to be a cable provider or telecom like everyone else that uses the poles. That seems fair to me. Come on Google go buy another company and run some wires!
Is VOIP + 911 service enough to get you qualified as a telecom provider? AT&T might regret asking Google to undercut them on phone service ...
If the background radiation was 100x hotter, would there have been a lot more hard radiation flying about as well?
I just picked up a Nook HD for my mom for $80. The Nook skin for Android is pretty simple, the 7" platform is light enough to hold up when reading ebooks, and the display is still good enough for movies/great for reading books. The only trick is to watch flash video you need to add a browser like Puffin.
Don't confuse appetite inhibitors with stimulants please, almost no doctor in his/her right mind would prescribe stimulants to obese people (they'd just eat more to compensate),
Phentermine is a stimulant with effects similar to amphetamines. It is still prescribed for weight loss both on its own (suprenza) and in combination with other drugs (Qsymia).
Interestingly you can take 400mg a day of topiramate for neurological conditions without a warning, but if you take 23mg a day for weight loss you have to be warned of the risk. Not that there is a bias against obesity or anything...
They added a warning about topamax/topiramate and pregnancy a little while ago, but it's the "benefits may exceed the risks" type warning, not a black boxed warning. If you're taking a topiramate containing drug to lose weight I'd guess they would say to just skip it for 9 months.
TOPAMAX® (topiramate) can cause fetal harm when administered to a pregnant woman. Data from pregnancy registries indicate that infants exposed to topiramate in utero have an increased risk for cleft lip and/or cleft palate (oral clefts). When multiple species of pregnant animals received topiramate at clinically relevant doses, structural malformations, including craniofacial defects, and reduced fetal weights occurred in offspring. TOPAMAX® should be used during pregnancy only if the potential benefit outweighs the potential risk. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to a fetus.
A big problem with keeping weight off is it takes a long time for your body to adjust to the new normal. Losing 10% of your bodyweight can adjust the levels of appetite-related hormones so that they resemble those of someone who is truly starving, and they can stay like that for 6 months or more. Basal metabolism is also decreased after weight loss, so that for someone to maintain their new weight they have to eat less than a twin of that same weight/activity level who hadn't recently lost weight. A drug that helps you maintain weight loss during that adjustment period might get a lot of people over the hump, at which point they could quit taking the drug.
but if you just want to tell people stuff
Telling people stuff is fine, but once you charge for the service you open yourself up to regulation. For years I've thought that the direct-to-consumer genetic testing industry would end up split into companies that charged to sequence your DNA on the one hand and free software that interpreted the data on the other. Originally I thought this would be the way to avoid infringing the thousands of patents on DNA tests a paid service would run afoul of, but now that DNA patents have been sharply limited I think this shift might still happen in order to escape FDA problems.
Ask for a refund - but first give them a quick quiz on conditional probability.
Actually if the research involves human subjects and is intended to support a product that would require FDA approval an IRB is required even if the funding is all private. The FDA has rules about how IRBs must be formed, but I dont' think they certify them. 23andMe and the companies it sells data/research services to might be exempt though since they could claim the data wasn't collected for any particular study: the data just happened to be available after customers plonked down their $99.
Those are the results of individual FDA approved genetic tests.
A "secondary market" for running thousands of tests at once would run into the same problem that 23andMe did: if you are going to sell diagnostic services in the USA then you will need to get FDA approval. The options are to only provide raw data and let someone else generate the report for free (see Promethease, mentioned below) or move the whole company someplace where law enforcement won't bother it. I could see 23andMe spinning off an independent foundation that would generate free reports, thus allowing their core business (building up a database of peoples DNA and personal/family medical histories that they can rent out for medical research free from the normal regulatory hurdles) to proceed unhindered. They would just have to be very careful to make certain there was no linkage between the for profit and the free companies: the non-profit would have to generate reports from data of any source, not just SNPs from 23andMe, it couldn't share any board members or employees with 23andMe, Google, etc.
Next legal challenge for 23andMe: doing medical research on people (gathering their DNA and medical histories, analyzing, allowing 3rd parties to analyze, etc) without getting IRB approvals first.
Anyone know how music licensing compares to television licensing? Is it a matter of per play/acquiring monthly rights?
The main difference: TV and movie content owners are extremely selective about who they will license streaming rights to, at least for content that still has a high demand. They want the streaming platform they are affiliated with to succeed and the ones they aren't affiliated with to fail. On that note: the new head of the FCC just said he thinks it would be fine for ISPs to start charging Netflix extra, giving their own streaming solutions a competitive advantage.
You're forgetting why bands sign to labels to begin with: Advertising.
The record labels are the ones that can (and do) do the legwork to set up and promote concerts,
Which is now done by the band themselves on social media.
That leaves out the dominant form of advertising: payola. Major labels spend a lot to get songs on the radio, whether it's laundered through "independent promoters" or just cutting checks to Clear Channel. Then there's TV/Movies: the major labels are all affiliated with TV/movie studios, so the songs played on every teen-centric show are pretty strategically chosen.
Why I have Windows 8 on my desktop: it was cheaper than Windows 7.
For someone that already has XP, the cost has already been paid and there is no future cost. If you try to force such a user to upgrade they will quite understandably object.
Especially if the cost that has already been paid is zero. in 2011 Ballmer claimed 90% of Chinese copies of Windows were pirated.
I think the concerns over there are:
1. Exploits on unsupported copies of XP would be a drag on the economy.
2. Actually paying for Microsoft software would be a drag on the economy.
To solve the issue China should just buy Microsoft. Two birds with one stone: They could pay for Microsoft in US T-bills and then make China-specific versions of Windows based products and sell them at cost. Bonus: Microsoft products could behave ... oddly when installed in Taiwan.
RF Safe-Stop Shuts Down Car Engines With Radio Pulse
As the vehicle entered the range of the RF Safe-stop, its dashboard warning lights and dials behaved erratically, the engine stopped and the car rolled gently to a halt. Digital audio and video recording devices in the vehicle were also affected.''It's a small radar transmitter,' said Andy Wood, product manager for the machine. 'The RF [radio frequency] is pulsed from the unit just as it would be in radar, it couples into the wiring in the car and that disrupts and confuses the electronics in the car causing the engine to stall.'"
Should do the trick for the encrypted ones.
Hiring someone to pick it up once a week is certainly cheaper, but for an apartment complex that means the yard is full of poop 6 1/2 days out of seven.
Some friends of mine who have 5 dogs (the wife is a vet and ends up with a lot of rescues) redid their back yard with St. Augustine back in the spring. It's still looking great.
Cats are definitely for people who want a family relationship - with an angsty teenager. On a more serious note dogs do require a lot more responsibility and a lot more socialization; they are prone to behavioral disorders if they don't get it. I wish people who have no free time/spend little time at home would think about that before buying the cute puppy.
When industrial 3D printers can print sets of legos 1, at the same tolerance (10 micron) as legos made from a mold, 2, cheaper than wholesale legos made from a mold you'll definitely have a point. Until then I think we'll see a much bigger impact from using 3D printing to make molds, prototypes, and one offs than from making actual consumer items. And I know the argument is that people will have a printer at home or use a printing service, thus cutting costs by getting rid of a long chain of transport and middle men. But people don't actually spend much on things that are purely 3D printable, and when things break it's usually not just a user-replaceable 3D printable plastic part at fault.
Hmmm...Time to take a weather balloon and a big sheet of aluminized mylar on a frame and let them out right in the line of sight and do something that makes money when their communications slow down.
Like charging $10k per minute to not drop microwave chaff in their line of sight? I like it.
Your neighbor must have a speed of light (in air) connection to the stock marketz! Please send me your brochure.
What does China do again? Provide cheap labor? 3D printing will eliminate that advantage.
China Provides cheap labor, lax environmental and zoning restrictions, entire cities organized around particular industries ... 3D printing is a very expensive and very slow way to manufacture pieces of plastic or metal in small quantities. If it was a fast and inexpensive way to make things by the gross they would make things that way in China. Instead they make 3D printers (stepper motors, motor drivers, microcontrollers, wires and connectors, etc) and sell them to us.
Just accumulate all of the orders for one second. At the end of each second match the closest buy/sell orders to each other and execute the trades. Repeat.
Oops
The advantage of (real) Supercomputers is that they can tackle large scale simulations (instead of large numbers of small scale simulations, which is what "Folding@Home" and co. do). Would the quality of the predictions go up if they used a more accurate (and thus computationally complex) model of the forcefield?
It would certainly help when it comes to electrostatics: solving the full nonlinear Poisson Boltzmann equation (as opposed to approximations) for all the atoms in the solvent, protein, and drug molecules is a bitch; doing it several billion times during a simulation is ... bitch x 10^9. The problem right now is that predictions from first principles of much simpler systems still tend to get a lot of things wrong: they're really only beginning to get a handle on how water works at this scale.
The advantage of (real) Supercomputers is that they can tackle large scale simulations (instead of large numbers of small scale simulations, which is what "Folding@Home" and co. do). Would the quality of the predictions go up if they used a more accurate (and thus computationally complex) model of the forcefield? It would certainly help when it comes to electrostatics: solving the full nonlinear Poisson Boltzmann equation (as opposed to approximations) for all the atoms in the solvent, protein, and drug molecules is a bitch; doing it several billion times during a simulation is ... bitch x 10^9. The problem right now is that predictions from first principles of much simpler systems still tend to get a lot of things wrong: they're really only beginning to get a handle on how water works at this scale.