If only they did it multi layerd.. as each layer was peeled off on the fascade..multiple prompts to surface... Are you sure you want take this logo down? This type of application can harm your computer...
Thats why i dont use a password..or at the very least... So the combination is... one, two, three, four, five? That's the stupidest combination I've ever heard in my life! The kind of thing an idiot would have on his luggage!
You know, it's really nice outside here in the north east, who is up for some touch football? But be forwarned, I'm going to pick my players based on skill, 'cause I'm all bias like that.
Before you start a diatribe, consider the following logic that I used, that I was otherwise unclear in my statements:
Most Chemotherapy is based on inhibiting processes of 'normal' cells by inhibiting specific cell replication mechanisms. Alternating electric fields inhibit specific cell replication mechanisms.
Therefore, 'regular' chemotherapy and Efield chemotherapy are based on similar principles.
If you were to compare my logic to yours, it would actually equate to the following: All dogs are mammals All cats are mammals Therefore, *dogs and cats must be related*
From the original article that states the technology: "interference with the proper formation of the mitotic spindle, whereas the second results in rapid disintegration of the dividing cells" [the disintegration they speak of is pore formation. http://cancerres.aacrjournals.org/cgi/content/full /64/9/3288
FYI, for instance, vincristine messes with the assembly of tubulin into microtubules, which make up the mitotic spindles.. hrmmmmmm. That does sound familar!
And no, I wasn't talking out of my butt, I just happen to know about Chemotherapy and I actually read the Journal Article.
I'm sorry that you're having to deal with cancer. It certainly is an uphill battle.
Nothing can be more experiential than actually going through the treatment yourself, and I applaud you on your efforts to research and figure out what's going on..
In regards to #2, it's a matter of symantecs. It is true, they do not divide faster, so to speak, they divide more often. The reason for this is (at least, so far mostly, for which mechanisms have been elucidated,) is because certain elements of the cell (ie proteins,) regulate steps within the normal cell cycle that would normally, prevent it from dividing in the case of damage, for instance. Most of the chemotherapy (other than specific ones, such as EGF or VEGF, which are designed to limit the effects of endogenously derived 'growth' stimulators, that although not in excess, the cells become super responsive to,) is openly, as you can attest to, are really a shot in the dark.
The idea of most chemotherapy (other than the specific ones..) is to damage the cell before it has a chance to repair itself. Cells that are constantly dividing don't have a chance, nor do they have the ability (in a variety of cancers,) to repair themselves, and in the process die.
The differences in the hair loss, diarrhea etc. (Although, there are some other processes involved in a variety of side effects, but the major ones are due to the relative cytotoxicity,)is due to the intrinsic nature of the cells involved and the chemotheraputic agent used. ie case and point with your Blood brain barrier example.
As you and I both said, this new finding could be very fantastic.. but its hard to say what long term effects it will have nor its relative precision.
The basis of all chemotherapy and the like has constantly focused on the fundamental differences between cancerous cells and normal cells: ie the fact that they're not dividing rapidly.
This is why people who receive chemo have problems with diarrhea and hair loss.. it just so happens that those cells are rapidly dividing and are affected just as well.
However, other treatments (few and far between,) such for Chronic Mylogenous Leukemia using Gleevac, which is designed to target the BCR-ABL fusion protein or Herceptin, used against breast cancers that overexpress ErbB2 receptor, are both novel in the sense that they exploit even more unique features of the cancer. That's what makes them so fantastic.
This new therapy won't provide too many benefits as far as the nastyness of treatment b/c it works just like chemo (in the case of metastases.) However, in the case of solid tumors ie GBM schwannomas, etc. perhaps it could be useful.
By the way, 10 patients is nearly not enough to be conclusive in any respect.
You know, a couple of things that would make this a bit clearer while trying minimize the confounding variables..
1. Sales vs Marketing dollars spent. (in contrast to XP,) 2. Sales vs Computer OEM / bundled licenses 3. General sales vs. MS Software assurance purchases? Does that figure include SA? hmmm.
I also find it interesting that Vista is hitting the market so hard in consideration of the hardware considerations. That's limited my corporate corner with Vista. Also, I know personally that I'm not about to install any major MS product in a production environment until SP1 or the equivalent comes out... That includes my home PC / laptop (well, maybe the laptop for kicks..)
I agree with what you have going there.. But a few points.
1. 85%+ of all women over 50 are infected with HPV.. Many men can be carriers and not even know it. Meaning, a woman (who is a virgin, for instance,) could marry a man who has had sex before, and contract HPV. This strengthens the argument against the religious fanatic who says boo hoo to vaccination.
2. A point to twist your noodle.. You mentioned the MMR (measles, mumps rubella,) vaccination to virtually 'irradicate' disease.. well, here's an interesting point: Rubella ain't that bad. The point of vaccinating people is not to protect themselves, but in the case that they become pregnant, protect the baby, because contracting Rubella in utero has some serious serious complications. So, is it ethical to subject millions of people to the possible side effects of rubella vaccination to save unborn children? hmmm think about that, and apply;)
well the thing is that long term it jobs are hard to come by. your best bet for that is in fortune 500 companies it teams... but don't expect autonomy. while looking I suggest doing some consulting jobs and side programming projects. that willl keep you busy and xashflow positive while you look. fyi I staryed my own consulting firm and that has dine well but the competition is fierce. as a result I'm here at a recital but I have to be accessible 24 7... hencw the treo 650 which is awesome btw
Great how this software does not discuss where it comes into play..
Assumingly through a proxy, or web portal software...
But if it integrates into IE, Opera, Firefox, or whatever... which one will be chosen... Will there be a monopoly on Inter user exchange of data? Oh my!
Suddenly I'm reminded of an old cartoon with Marvin the Martian and Bugs Bunny. Interestingly, all i can remember is enough planet for just one of them to stand on..
An interesting point that I can't help but think of...
This reminds me of when the government had a so-called plan to place regulation or taxation on email?
This gives me an overwhelming sense of the ability to go ahead and 'tax' such a service.
Imagine the amount of 'unregulated' businesses and personal consumers using this particular product. Would it be possible to regulate this effectively? Imagine the change in protocol for email taxation? This leads us to the realization of why SPAM has become such a problem. It's inherent in the design of email.
To tax something like VoIP is rediculously complicated, and I often wonder if the scope is beyond the capabilities of our government, more or less the world's government.
Also, in response to taxation on various different items depending on the strict uses of the funds accumulated as a result of such taxation (ie taxes on gasolines used for building/maintaining roads.): Everyone will agree that taxes are a bad thing, who wants to get money taken away that they've rightfully earned?
It's complicated, but lots of our taxes *are* put to good use (Don't get me wrong, a lot of money is spent on frivelous things, but its hard to control everything. We have to take the good with the bad.. It's the facts of life!) Many salaries are created with taxes, taxes fund research in healthcare and technology, defense, etc. etc. etc.
Can't we attribute (partially) the development of the internet (yeay slashdot,) to the government, or has everyone forgotton arpa?
I'm wondering. Was there talk about changing the SMTP protocol a while back? I know it would a major overhaul, something along the lines of revamping IPv4 to IPv6 (well, not that major..)
This flys right around there with 'taxing every email' which would be an interesting debate indeed.
I've noticed that a bunch of mail servers out there are now doing creative mail filtering, making sure that the mx record corresponds to the actual relay that the mail is coming through. But not everyone has smtp auth over pop..
For instance, my new favourite is AOLmail.. almost any external mail to any aol servers, now takes up to several hours to actually get through their systems. I'm not sure if this is a creative filtering process, or that their servers are just so bogged down?
Unfortunately this is slightly against the law, and they only way this could actually fly is if a couple of white hackers get down and take care of it themselves...
I'm a member of a community called New York City Wireless..(www.nycwireless.org, iirc)
I heard about this community from a guy named Bill Weikling (spellng?) he's the dood who set up the entirely large co-op in hawaii. (NON PROFIT)(http://www.workingwireless.com)
The users of this community, now that is has gotten larger are getting a lot of flack from local providers. And the funny thing is that the bandwidth (whether purchased for home use, or for business use) is given away for free to the wireless users.
the logic is that the business users purchase their bandwidth at a set rate, and they should be able to do whatever they wish with it. But they are still getting flack for it... odd, isn't it?
This is a great project, and although it's free, I would hate to see it go. It's fun to walk into manhattan and turn on your laptop... and get a signal:)
That was a good laugh.. and my friends.. that's why it was posted to/.:)
I've been IRC'ing since 1992. That's 10 years, and I'm still not a veteran.
Some of the World's (Internet's) greatest heros and founders hang out on EFNet/IRC or some like service...
Remember BBS?:) Surprised they didn't talk about that.
It's so typical for people to lash out on things they do not understand. More or less, its all too typical that they never emphasize the best parts about it. I mean comon.. Let's think about it.
IRC is a place to share knowledge, not just CC #'s (who are they kidding.. I have never been asked to trade a CC # or anything of the like.) Many of the World's 'hackers' (or techies that work for YOUR company) can acredit their knowledge (or at least the start) to IRC. I know I can.
I knew nothing (well, not nothing, a tincy bitty bit) about the Internet, its structure, protocols, computers, other operating systems, etc. before I came to IRC.
It all started with the 'need' to have an eggdrop bot in my channel.. How the hell was I to do this?
*shrug* I didn't know what I was doing.. but I got my hands on a free WOPR.net shell, (if anyone knows who I'm talking about.. send a shout out.. I'm curious) and was forced to learn a bit of unix commands (heh) to opperate the bot...
By and by I had shell after shell.. learning more about *nix as the opportunity came along. I eventually had the oppertunity to have root on a friends system (from IRC) and learned more and more about the system and how it worked.
Fast forward a bunch of years:) I met both my partners of my company (Web Hosting/Web Development) on IRC, and they have been good friends ever since. It is quite the successful business, and I have learned much since then... all because of IRC (well, I guess not that much.. I'm still using/.;)
The news concentrates on the bad things always.. I've become a better person because of IRC, completely. Not only have I learned a tone of IT stuff.. I've also learned how to be a;better person.. to react in the right mannor (not just to get +o.. or plus +O for that matter;0)
Much of the Internet success stories are because of IRC, and I feel this article fails to discuss this... That is a bad thing, and this is why us 'hackers' seem to get a bad rep.
Oh yeah.. IRC didn't teach me how to spell, really:) afaik:)
My father worked for the government.. and I got to take a peak at their offices several times..
I have to say, if I was in the IT industry (heh, i am, but not in this case) and had this opportunity..
Why the hell not. In today's unstable IT world, this can be a very good thing.
Once you work for the government for these 12months or whatever it may be.. you're established. Chances are, they'll be asking you to work for them.
Makes sense. The government wants fresh workers working for them. Maybe take a new idea/view towards things. Afterall, shouldn't our government be the ones best up on all the latest and greatest? I'm sure the idea is that they want to snatch the really good admins up, and use em to their benifit, and hopefully they'll stick with the government.
Consider our current status: We're *sort of* at war with another country. The biggest talks of terrorist attacks are in the Internetworking issues, and that's where everyone predicts will get hit next. Wouldn't you think that the government wants to tighten up security all around..
The Job security might proove to be a good thing for the average IT worker. Especially since once you get established in the government as a worker.. you'll have a rating, which is your level of work in the government. I don't recall exactly how the levels go, but the higher the level.. the more $:) They're more likely to higher you too if you have experience in the government.. it's a nice fallback plan.
Slashdot Mirror
Im not sure about this because i havent been keeping tab... but i thought widespread nat'ing pushed ipv6 the way ofnthe dodo
I think arin needs to be a little less lax about their assignments btw.. you can get a /20 with two linksys routers and an ipad these days..
If only they did it multi layerd..
as each layer was peeled off on the fascade..multiple prompts to surface...
Are you sure you want take this logo down?
This type of application can harm your computer...
Thats why i dont use a password..or at the very least...
So the combination is... one, two, three, four, five? That's the stupidest combination I've ever heard in my life! The kind of thing an idiot would have on his luggage!
Might as well give up now, and just stop reading.
You know, it's really nice outside here in the north east, who is up for some touch football? But be forwarned, I'm going to pick my players based on skill, 'cause I'm all bias like that.
Before you start a diatribe, consider the following logic that I used, that I was otherwise unclear in my statements:
l /64/9/3288
Most Chemotherapy is based on inhibiting processes of 'normal' cells by inhibiting specific cell replication mechanisms.
Alternating electric fields inhibit specific cell replication mechanisms.
Therefore, 'regular' chemotherapy and Efield chemotherapy are based on similar principles.
If you were to compare my logic to yours, it would actually equate to the following:
All dogs are mammals
All cats are mammals
Therefore, *dogs and cats must be related*
From the original article that states the technology:
"interference with the proper formation of the mitotic spindle, whereas the second results in rapid disintegration of the dividing cells" [the disintegration they speak of is pore formation.
http://cancerres.aacrjournals.org/cgi/content/ful
FYI, for instance, vincristine messes with the assembly of tubulin into microtubules, which make up the mitotic spindles.. hrmmmmmm. That does sound familar!
And no, I wasn't talking out of my butt, I just happen to know about Chemotherapy and I actually read the Journal Article.
I'm sorry that you're having to deal with cancer. It certainly is an uphill battle.
Nothing can be more experiential than actually going through the treatment yourself, and I applaud you on your efforts to research and figure out what's going on..
In regards to #2, it's a matter of symantecs. It is true, they do not divide faster, so to speak, they divide more often. The reason for this is (at least, so far mostly, for which mechanisms have been elucidated,) is because certain elements of the cell (ie proteins,) regulate steps within the normal cell cycle that would normally, prevent it from dividing in the case of damage, for instance. Most of the chemotherapy (other than specific ones, such as EGF or VEGF, which are designed to limit the effects of endogenously derived 'growth' stimulators, that although not in excess, the cells become super responsive to,) is openly, as you can attest to, are really a shot in the dark.
The idea of most chemotherapy (other than the specific ones..) is to damage the cell before it has a chance to repair itself. Cells that are constantly dividing don't have a chance, nor do they have the ability (in a variety of cancers,) to repair themselves, and in the process die.
The differences in the hair loss, diarrhea etc. (Although, there are some other processes involved in a variety of side effects, but the major ones are due to the relative cytotoxicity,)is due to the intrinsic nature of the cells involved and the chemotheraputic agent used. ie case and point with your Blood brain barrier example.
As you and I both said, this new finding could be very fantastic.. but its hard to say what long term effects it will have nor its relative precision.
The article states that the cells in the brain don't really replicate or regenerate.
t ml
However, recent research has shown that cells in the area of the hippocampus do in fact replicate, and are indicated in the role they play in cancer:
Take a peak:
http://www.biopsychiatry.com/newbraincell/index.h
The basis of all chemotherapy and the like has constantly focused on the fundamental differences between cancerous cells and normal cells: ie the fact that they're not dividing rapidly.
This is why people who receive chemo have problems with diarrhea and hair loss.. it just so happens that those cells are rapidly dividing and are affected just as well.
However, other treatments (few and far between,) such for Chronic Mylogenous Leukemia using Gleevac, which is designed to target the BCR-ABL fusion protein or Herceptin, used against breast cancers that overexpress ErbB2 receptor, are both novel in the sense that they exploit even more unique features of the cancer. That's what makes them so fantastic.
This new therapy won't provide too many benefits as far as the nastyness of treatment b/c it works just like chemo (in the case of metastases.) However, in the case of solid tumors ie GBM schwannomas, etc. perhaps it could be useful.
By the way, 10 patients is nearly not enough to be conclusive in any respect.
You know, a couple of things that would make this a bit clearer while trying minimize the confounding variables..
1. Sales vs Marketing dollars spent. (in contrast to XP,)
2. Sales vs Computer OEM / bundled licenses
3. General sales vs. MS Software assurance purchases? Does that figure include SA? hmmm.
I also find it interesting that Vista is hitting the market so hard in consideration of the hardware considerations. That's limited my corporate corner with Vista. Also, I know personally that I'm not about to install any major MS product in a production environment until SP1 or the equivalent comes out... That includes my home PC / laptop (well, maybe the laptop for kicks..)
-paul
I agree with what you have going there.. But a few points.
;)
1. 85%+ of all women over 50 are infected with HPV.. Many men can be carriers and not even know it. Meaning, a woman (who is a virgin, for instance,) could marry a man who has had sex before, and contract HPV. This strengthens the argument against the religious fanatic who says boo hoo to vaccination.
2. A point to twist your noodle.. You mentioned the MMR (measles, mumps rubella,) vaccination to virtually 'irradicate' disease.. well, here's an interesting point:
Rubella ain't that bad. The point of vaccinating people is not to protect themselves, but in the case that they become pregnant, protect the baby, because contracting Rubella in utero has some serious serious complications. So, is it ethical to subject millions of people to the possible side effects of rubella vaccination to save unborn children? hmmm think about that, and apply
well the thing is that long term it jobs are hard to come by. your best bet for that is in fortune 500 companies it teams... but don't expect autonomy. while looking I suggest doing some consulting jobs and side programming projects. that willl keep you busy and xashflow positive while you look. fyi I staryed my own consulting firm and that has dine well but the competition is fierce. as a result I'm here at a recital but I have to be accessible 24 7... hencw the treo 650 which is awesome btw
Why don't they just confront Slashdot users... and make it open game for Slashdotters..
'Hey slashdot.. here's our network.. do your worst'
Or is that.. too much of a security risk to allow people open knowledge to try and exploit systems that normally, their presence would be unknown?
Maybe they should follow the 'don't write down passwords' routine M$ has suggested...
If he doesn't have a credit card.. how is he paying for this mysterious satellite?
Or is he pirating it?
Great how this software does not discuss where it comes into play..
Assumingly through a proxy, or web portal software...
But if it integrates into IE, Opera, Firefox, or whatever... which one will be chosen... Will there be a monopoly on Inter user exchange of data? Oh my!
Suddenly I'm reminded of an old cartoon with Marvin the Martian and Bugs Bunny. Interestingly, all i can remember is enough planet for just one of them to stand on..
An interesting point that I can't help but think of...
This reminds me of when the government had a so-called plan to place regulation or taxation on email?
This gives me an overwhelming sense of the ability to go ahead and 'tax' such a service.
Imagine the amount of 'unregulated' businesses and personal consumers using this particular product. Would it be possible to regulate this effectively? Imagine the change in protocol for email taxation? This leads us to the realization of why SPAM has become such a problem. It's inherent in the design of email.
To tax something like VoIP is rediculously complicated, and I often wonder if the scope is beyond the capabilities of our government, more or less the world's government.
Also, in response to taxation on various different items depending on the strict uses of the funds accumulated as a result of such taxation (ie taxes on gasolines used for building/maintaining roads.): Everyone will agree that taxes are a bad thing, who wants to get money taken away that they've rightfully earned?
It's complicated, but lots of our taxes *are* put to good use (Don't get me wrong, a lot of money is spent on frivelous things, but its hard to control everything. We have to take the good with the bad.. It's the facts of life!) Many salaries are created with taxes, taxes fund research in healthcare and technology, defense, etc. etc. etc.
Can't we attribute (partially) the development of the internet (yeay slashdot,) to the government, or has everyone forgotton arpa?
I'm wondering. Was there talk about changing the SMTP protocol a while back? I know it would a major overhaul, something along the lines of revamping IPv4 to IPv6 (well, not that major..)
This flys right around there with 'taxing every email' which would be an interesting debate indeed.
I've noticed that a bunch of mail servers out there are now doing creative mail filtering, making sure that the mx record corresponds to the actual relay that the mail is coming through. But not everyone has smtp auth over pop..
For instance, my new favourite is AOLmail.. almost any external mail to any aol servers, now takes up to several hours to actually get through their systems. I'm not sure if this is a creative filtering process, or that their servers are just so bogged down?
hrm?
Unfortunately this is slightly against the law, and they only way this could actually fly is if a couple of white hackers get down and take care of it themselves...
What about those of us who like those LARGE, NOISEY, SPACE HEATER... machines..
I mean, it makes me feel like I'm at work in the server room.. all the time,.. helps me sleep.
What about us?
-Paul
just download it like any normal computer loving, LOTR fan would do :P
I'm a member of a community called New York City Wireless..(www.nycwireless.org, iirc)
:)
I heard about this community from a guy named Bill Weikling (spellng?) he's the dood who set up the entirely large co-op in hawaii. (NON PROFIT)(http://www.workingwireless.com)
The users of this community, now that is has gotten larger are getting a lot of flack from local providers. And the funny thing is that the bandwidth (whether purchased for home use, or for business use) is given away for free to the wireless users.
the logic is that the business users purchase their bandwidth at a set rate, and they should be able to do whatever they wish with it. But they are still getting flack for it... odd, isn't it?
This is a great project, and although it's free, I would hate to see it go. It's fun to walk into manhattan and turn on your laptop... and get a signal
That was a good laugh.. and my friends.. that's why it was posted to /. :)
:) Surprised they didn't talk about that.
:) I met both my partners of my company (Web Hosting/Web Development) on IRC, and they have been good friends ever since. It is quite the successful business, and I have learned much since then... all because of IRC (well, I guess not that much.. I'm still using /. ;)
;better person.. to react in the right mannor (not just to get +o.. or plus +O for that matter ;0)
:) afaik :)
I've been IRC'ing since 1992. That's 10 years, and I'm still not a veteran.
Some of the World's (Internet's) greatest heros and founders hang out on EFNet/IRC or some like service...
Remember BBS?
It's so typical for people to lash out on things they do not understand. More or less, its all too typical that they never emphasize the best parts about it. I mean comon.. Let's think about it.
IRC is a place to share knowledge, not just CC #'s (who are they kidding.. I have never been asked to trade a CC # or anything of the like.) Many of the World's 'hackers' (or techies that work for YOUR company) can acredit their knowledge (or at least the start) to IRC. I know I can.
I knew nothing (well, not nothing, a tincy bitty bit) about the Internet, its structure, protocols, computers, other operating systems, etc. before I came to IRC.
It all started with the 'need' to have an eggdrop bot in my channel.. How the hell was I to do this?
*shrug* I didn't know what I was doing.. but I got my hands on a free WOPR.net shell, (if anyone knows who I'm talking about.. send a shout out.. I'm curious) and was forced to learn a bit of unix commands (heh) to opperate the bot...
By and by I had shell after shell.. learning more about *nix as the opportunity came along. I eventually had the oppertunity to have root on a friends system (from IRC) and learned more and more about the system and how it worked.
Fast forward a bunch of years
The news concentrates on the bad things always.. I've become a better person because of IRC, completely. Not only have I learned a tone of IT stuff.. I've also learned how to be a
Much of the Internet success stories are because of IRC, and I feel this article fails to discuss this... That is a bad thing, and this is why us 'hackers' seem to get a bad rep.
Oh yeah.. IRC didn't teach me how to spell, really
I think your take on the situation is quite jaded and scornful.
:)
Do you have it in for the government...
or are you afraid?
Coward
This should be interesting.
:) They're more likely to higher you too if you have experience in the government.. it's a nice fallback plan.
:)
My father worked for the government.. and I got to take a peak at their offices several times..
I have to say, if I was in the IT industry (heh, i am, but not in this case) and had this opportunity..
Why the hell not. In today's unstable IT world, this can be a very good thing.
Once you work for the government for these 12months or whatever it may be.. you're established. Chances are, they'll be asking you to work for them.
Makes sense. The government wants fresh workers working for them. Maybe take a new idea/view towards things. Afterall, shouldn't our government be the ones best up on all the latest and greatest? I'm sure the idea is that they want to snatch the really good admins up, and use em to their benifit, and hopefully they'll stick with the government.
Consider our current status:
We're *sort of* at war with another country. The biggest talks of terrorist attacks are in the Internetworking issues, and that's where everyone predicts will get hit next. Wouldn't you think that the government wants to tighten up security all around..
The Job security might proove to be a good thing for the average IT worker. Especially since once you get established in the government as a worker.. you'll have a rating, which is your level of work in the government. I don't recall exactly how the levels go, but the higher the level.. the more $
yup, I'd take it