No, it had a big gross, and if you had points off the gross you were good. But if you had points off the net, you are screwed. There will be no net. There will not be a profit.
Hollywood really isn't interested in making good movies, it's interested in tie-ins. Spiderman 3 had more characters to make action figures out of to be sold at McDonalds or Wendys or whatever.
Spiderman, Spiderman Agent told him it was in the can. But the suits missed the scoop Now his Raimi has flown the coop Lookout! There goes your Spiderman!
That doesn't represent the cost of taking any one drug to market. The represents the cost of putting drugs through trials plus the cost of wasted research into dead-end areas plus all the organizational overhead of those research units plus god knows what else.
True, the cost to bring a single drug to market is far less. Now all you have to do is go back ten years to the benchtop chemist and tell him or her which one of the 500 structures they are working on is that one so they can ignore all the rest.
Seeing as how the average cost to a major pharma to bring a drug from the bench of the medicinal chemist to the bottle in your medicine cabinet is approaching a billion dollars, having only $60 million to work with seems like running on a shoestring.
Tablet shmablet. Do you see the ads on TV for the Dell computer with touchscreen? Can you imagine the hurt you would be in after an hour or so with your arm raised up off the desk to reach the screen?
That's nothing. Where I work, we have go outside, and chew the leaves and beans off coffee bushes ourselves.
Right. I had to get up in the morning at ten o'clock at night half an hour before I went to bed, drink a cup of sulphuric acid, work twenty-nine hours a day down mill, and pay mill owner for permission to come to work, and when we got home, our Dad and our mother would kill us and dance about on our graves singing Hallelujah.
If the expression of pi in any base is random, eventually any message you want will be found within it. You do not need 1000K monkeys to output all of some dead guy's work, which is good, because that would be a lot of monkey doo you would have to clean up waiting for them to finish. And you would have copyright problems to boot.
Things change. Young people embrace it, old people rooted in the old way bitch and moan about it. Rinse, repeat.
I'm not so sure that the meme of the young being early adopters and the old being Luddites is uniformly correct. Sure, some of it is familiarity, but there is a mindset which is independent of physical age. There is a willingness to try new things not related to calendar years. My mother has a website, she Twitters, she blogs, and she is pushing 80. My mother in law would not look at a computer and relied on an electric typewriter.
At work, some of the fresh college graduates are happy to write down their lot records on paper and file them in manila folders.
I did not RTFA, and I will not RTFA. My spidey sense tells me what is in it (and in the book, which I will also not R) - a needlessly long piece of prose which can be summarized as : Get off my virtual lawn. and Gee, everything was so much better when I was young.
Alexie is a Native American. Those people have no sense of ownership anyway. Their tribes roam from book to book. It wasn't until the white man arrived with his culture of printing out books and putting his name on them and getting all upset if the Indians took them off the shelf and didn't return them within two weeks that the trouble started.
Slashdot Mirror
No, it had a big gross, and if you had points off the gross you were good. But if you had points off the net, you are screwed. There will be no net. There will not be a profit.
http://en.wikipedia.org/wiki/Hollywood_accounting
Hollywood really isn't interested in making good movies, it's interested in tie-ins. Spiderman 3 had more characters to make action figures out of to be sold at McDonalds or Wendys or whatever.
And yet the film still hasn't turned a profit.
Spiderman, Spiderman
Agent told him it was in the can.
But the suits missed the scoop
Now his Raimi has flown the coop
Lookout! There goes your Spiderman!
It will give me superpowers, right?
Yes. You will have the power to invent new and better memes.
Isn't she Alton Brown's equipment connection?
But once a promising compound has been found
That was my point.
Once I pick the right numbers, the Maga Millions will be mine.
Of course I meant Mega Mullions.
But once a promising compound has been found
That was my point.
Once I pick the right numbers, the Maga Millions will be mine.
That doesn't represent the cost of taking any one drug to market. The represents the cost of putting drugs through trials plus the cost of wasted research into dead-end areas plus all the organizational overhead of those research units plus god knows what else.
True, the cost to bring a single drug to market is far less. Now all you have to do is go back ten years to the benchtop chemist and tell him or her which one of the 500 structures they are working on is that one so they can ignore all the rest.
Seeing as how the average cost to a major pharma to bring a drug from the bench of the medicinal chemist to the bottle in your medicine cabinet is approaching a billion dollars, having only $60 million to work with seems like running on a shoestring.
Tablet shmablet. Do you see the ads on TV for the Dell computer with touchscreen? Can you imagine the hurt you would be in after an hour or so with your arm raised up off the desk to reach the screen?
Real scientists have a very different opinion on the subject of AGW.
As do true Scotmen.
Great, now every porn flick is going to look like a Gallagher concert.
tThHiIsS iIsS tThHeE vVeErRyY fFiIrRsStT tThHrReEeE dD pPoOsStT
cCaAuUtTiIoOnN mMaAyY cCaAuUsSeE nNaAuUsSeEaA
What do they call "WHOOSH" over there?
Nasty instant Coffee?
That's nothing. Where I work, we have go outside, and chew the leaves and beans off coffee bushes ourselves.
Right. I had to get up in the morning at ten o'clock at night half an hour before I went to bed, drink a cup of sulphuric acid, work twenty-nine hours a day down mill, and pay mill owner for permission to come to work, and when we got home, our Dad and our mother would kill us and dance about on our graves singing Hallelujah.
If the expression of pi in any base is random, eventually any message you want will be found within it. You do not need 1000K monkeys to output all of some dead guy's work, which is good, because that would be a lot of monkey doo you would have to clean up waiting for them to finish. And you would have copyright problems to boot.
Who cares if it exists or not? I find that if I search for it vigorously with fingers, tongue, and penis, she gets the desired result.
I'm pretty sure I will recognize the net in 2020. People always overestimate the rate of change in the future.
Things change. Young people embrace it, old people rooted in the old way bitch and moan about it. Rinse, repeat.
I'm not so sure that the meme of the young being early adopters and the old being Luddites is uniformly correct. Sure, some of it is familiarity, but there is a mindset which is independent of physical age. There is a willingness to try new things not related to calendar years. My mother has a website, she Twitters, she blogs, and she is pushing 80. My mother in law would not look at a computer and relied on an electric typewriter.
At work, some of the fresh college graduates are happy to write down their lot records on paper and file them in manila folders.
I did not RTFA, and I will not RTFA. My spidey sense tells me what is in it (and in the book, which I will also not R) - a needlessly long piece of prose which can be summarized as : Get off my virtual lawn. and Gee, everything was so much better when I was young.
Alexie is a Native American. Those people have no sense of ownership anyway. Their tribes roam from book to book. It wasn't until the white man arrived with his culture of printing out books and putting his name on them and getting all upset if the Indians took them off the shelf and didn't return them within two weeks that the trouble started.
My town mistakenly ordered IED lights. These remove their own snow.
And the iSlate is its prophet. (Allah bless it and give it peace and clear wifi connections all of its battery life, may it be long.)
The problem with Chinese experimental homebuilt aircraft is, a half hour after you test fly it, you....
On Eminiar and Vendikar, they wanted more realism, and they got it.