Where did you see that a German national ID is required? Maybe I overlooked it in the article. I saw German resident but nothing about a German ID card. This is not a minor detail since 10% of German residents are not German and therefore do not have a German ID. Does this mean I can't receive these mails? Could make fiing my taxes interesting...
Or if no organs are suitable (think of hearts from obese individuals, kidneys from diabetics, someone who dies with cancer, etc., all becoming more and more common), this would be ideal. Right now, only the donor card option is easy but if the organs aren't suitable, it all goes in the bin...
It's not about the percentage. I probably pay even less taxes for roads than for education. However, I can still drive on the interstate in CA without paying any extra for it because it's a public good (like knowledge). Everyone with a car has the chance to drive for no additional cost on that freeway.
As for alternative sources of funding - my post high school education cost over $100,000. I paid for about 1/4 of that - the rest came from a private stipend.
I paid a lot of taxes last year. It's not unreasonable to argue that some of that money went towards funding the very educational facilities and research that you're talking about - why should I have to pay a second time?
While I agree that he's a crackpot, we are already at the point
where technological change would have *any* profound effects on us (my emphasis)
I'm involved in making a transgenic rat right now. Similar technology could be used to do the same to humans. It hasn't been yet (to my knowledge) and I hope it won't be but I would call mucking around with our genome a profound effect.
I demonstrate by knocking out a gene in mice that I can cure cancer. Let's pretend that this gene encodes an enzyme and given the mechanism of action that an enzyme inhibitor would have the same result. Suppose I'm not a huge pharmaceuticals company but at a university so I don't have the resources to generate such an inhibitor. Assume, however, demonstrating the idea that an inhibitor of this particular enzyme would cure cancer is novel (non-obvious) and let's pretend that the proof in this case is airtight. Is this not worth a patent just because the poor guy/girl doesn't have the 200 million dollars needed to bring such a drug to the market. Even generating an inhibitor that works in a mouse without killing it generally costs about 5 million.
You are therefore suggesting that the price of an anti-cancer patent be $5 million...
P.S. There are other reasons that such patents shouldn't be (but unfortunately are) granted - they actually hinder progress for one.
Of course, I realize that lots of GPL'd software is sold but then it's no different than commercial software in that sense. But if you paid nothing for software and youhave problems, what's the difference between that and someone who finds a free recipe on the net for muffins a, makes them and they taste bad ?
It's a common misconception that bacteria don't have sex. Many species do transfer genetic material, for example E. coli. This is called conjugation. Some E. coli strains contain the F' plasmid which encodes pili (think submicroscopic hair-like penises) which allows them to transfer the plasmid (or in rare "Hfr" strains, part of the main chromosome) to other recipient strains (you can consider them "male"-like). Very rarely this also appears to transfer to other species, which is one mechanism through which nasty things like antibiotic resistance genes jump the species barrier. Some bacteriophage (bacterial viruses) infect cells with pili so this tends to select against F' containing bacteria.
I don't want Amarock searching Wikipedia every time I'm listening to my mp3s. I already know who sang the song - they're my legal copies (not living in US).
Wouldn't it be a better use of resources to incorporate this into a browser or word processor? You could look highlight any word(s) on the web page and, like Firefox searches Google, search Wiki.
Jehovah's Witnesses oppose the transfusion of blood.
Only for themselves. They won't stop you getting a transfusion.
No, because they are a minor sect with little or no political clout. If they did have any, they would probably not be any different than any other religion, trying to foist their opinions onto others. When I say "they", I do realize that not all religious individuals act this way but somehow organized religions as a whole seem to.
There are some niche uses for B+W paper such as electron microscopy (I'm sure there must be others but I'm only a lowly biologist). Color paper just doesn't cut it.
Of corse, you're talking to someone who's made his own B+W glass slides. The resolution is really spectacular (great for EM) but they sometimes jam projectors made for the cheap mass-produced plastic slides. Of course, with everyone switching to digital projectors, their days are also numbered.
Nevertheless, I won't miss Kodak B+W paper, I prefer Ilford.
From the article: "the bulk of Linux systems sold end up with other operating systems, particularly pirated Windows, likening the situation to PCs that ship to China.
"I think they may end up with Windows," he said. "The stores just say, 'Look, it had an operating system on it when it went out the door. That's all we know. Hear no evil, see no evil."
I've always heard complaints that you can only buy PCs with XP (the whole refund thing). Or am I wrong (I built my own)?
Methotrexate is an old drug that inhibits DHFR (dihydrofolate reductase). Folate is needed to synthesize thymidine, one of the four building blocks of DNA. DNA synthesis is important for quickly growing cells (i.e., fast growing cancers - that's not all cancers of course). and explains the relative selectivity of MET for cancer cells (if the normal cell isn't growing, it doesn't need to make much DNA). Side effects of such chemo agents are largely due to their effects on quickly growing cells (hair, stomach lining, etc.). I find it interesting but also perhaps counterintuitive that they're using folate to deliver an anti-folate drug.
I expect that, in the real world, cells that are methotrexate resistant(a folate analogue) would be resistant to targeting via folate transporters...
Slashdot Mirror
I guess a giant radiator (i.e., closed loop) in the ocean as the last step would be ridiculously expensive.
Where did you see that a German national ID is required? Maybe I overlooked it in the article. I saw German resident but nothing about a German ID card. This is not a minor detail since 10% of German residents are not German and therefore do not have a German ID. Does this mean I can't receive these mails? Could make fiing my taxes interesting...
Or if no organs are suitable (think of hearts from obese individuals, kidneys from diabetics, someone who dies with cancer, etc., all becoming more and more common), this would be ideal. Right now, only the donor card option is easy but if the organs aren't suitable, it all goes in the bin...
It's not about the percentage. I probably pay even less taxes for roads than for education. However, I can still drive on the interstate in CA without paying any extra for it because it's a public good (like knowledge). Everyone with a car has the chance to drive for no additional cost on that freeway.
As for alternative sources of funding - my post high school education cost over $100,000. I paid for about 1/4 of that - the rest came from a private stipend.
I paid a lot of taxes last year. It's not unreasonable to argue that some of that money went towards funding the very educational facilities and research that you're talking about - why should I have to pay a second time?
While I agree that he's a crackpot, we are already at the point
where technological change would have *any* profound effects on us (my emphasis)
I'm involved in making a transgenic rat right now. Similar technology could be used to do the same to humans. It hasn't been yet (to my knowledge) and I hope it won't be but I would call mucking around with our genome a profound effect.
Ok, how about this example:
I demonstrate by knocking out a gene in mice that I can cure cancer. Let's pretend that this gene encodes an enzyme and given the mechanism of action that an enzyme inhibitor would have the same result. Suppose I'm not a huge pharmaceuticals company but at a university so I don't have the resources to generate such an inhibitor. Assume, however, demonstrating the idea that an inhibitor of this particular enzyme would cure cancer is novel (non-obvious) and let's pretend that the proof in this case is airtight. Is this not worth a patent just because the poor guy/girl doesn't have the 200 million dollars needed to bring such a drug to the market. Even generating an inhibitor that works in a mouse without killing it generally costs about 5 million.
You are therefore suggesting that the price of an anti-cancer patent be $5 million...
P.S. There are other reasons that such patents shouldn't be (but unfortunately are) granted - they actually hinder progress for one.
then I go back in time and convince them to open the patent office a day earlier ...
Stupid question: What's the use of an expired patent anyway ?
what do you expect to recover?
Of course, I realize that lots of GPL'd software is sold but then it's no different than commercial software in that sense. But if you paid nothing for software and youhave problems, what's the difference between that and someone who finds a free recipe on the net for muffins a, makes them and they taste bad ?
From a molecular biologist's viewpoint:
o pics/conjugation.html
It's a common misconception that bacteria don't have sex. Many species do transfer genetic material, for example E. coli. This is called conjugation. Some E. coli strains contain the F' plasmid which encodes pili (think submicroscopic hair-like penises) which allows them to transfer the plasmid (or in rare "Hfr" strains, part of the main chromosome) to other recipient strains (you can consider them "male"-like). Very rarely this also appears to transfer to other species, which is one mechanism through which nasty things like antibiotic resistance genes jump the species barrier. Some bacteriophage (bacterial viruses) infect cells with pili so this tends to select against F' containing bacteria.
A link I just found: http://www.mun.ca/biochem/courses/3107/Lectures/T
Cannabalism ?
I had one. It was basically a 486 computer on a card, with its own RAM. So when you switched over, your Mac was still running in the background.
Or James Taylor's "Fire and Rain", although it's not really about a literal plane crash
And you can charter one for about $5k/hour here: http://www.aircharternetwork.com/pages/faq.html
I don't want Amarock searching Wikipedia every time I'm listening to my mp3s. I already know who sang the song - they're my legal copies (not living in US).
Wouldn't it be a better use of resources to incorporate this into a browser or word processor? You could look highlight any word(s) on the web page and, like Firefox searches Google, search Wiki.
Wouldn't that be nice?
Jehovah's Witnesses oppose the transfusion of blood.
Only for themselves. They won't stop you getting a transfusion.
No, because they are a minor sect with little or no political clout. If they did have any, they would probably not be any different than any other religion, trying to foist their opinions onto others. When I say "they", I do realize that not all religious individuals act this way but somehow organized religions as a whole seem to.
There are some niche uses for B+W paper such as electron microscopy (I'm sure there must be others but I'm only a lowly biologist). Color paper just doesn't cut it.
Of corse, you're talking to someone who's made his own B+W glass slides. The resolution is really spectacular (great for EM) but they sometimes jam projectors made for the cheap mass-produced plastic slides. Of course, with everyone switching to digital projectors, their days are also numbered.
Nevertheless, I won't miss Kodak B+W paper, I prefer Ilford.
Sorry I wasn't clear. I meant: Isn't it likely that more XP systems get replaced with Linux than the other way around?
In German, the slang term term for a mobile phone is a "Handy". Funny thing, everyone thinks this is a real English word ...
From the article: "the bulk of Linux systems sold end up with other operating systems, particularly pirated Windows, likening the situation to PCs that ship to China. "I think they may end up with Windows," he said. "The stores just say, 'Look, it had an operating system on it when it went out the door. That's all we know. Hear no evil, see no evil."
I've always heard complaints that you can only buy PCs with XP (the whole refund thing). Or am I wrong (I built my own)?
Absolutely correct. There are probably better ways to do this, too ...
Methotrexate is an old drug that inhibits DHFR (dihydrofolate reductase). Folate is needed to synthesize thymidine, one of the four building blocks of DNA. DNA synthesis is important for quickly growing cells (i.e., fast growing cancers - that's not all cancers of course). and explains the relative selectivity of MET for cancer cells (if the normal cell isn't growing, it doesn't need to make much DNA). Side effects of such chemo agents are largely due to their effects on quickly growing cells (hair, stomach lining, etc.). I find it interesting but also perhaps counterintuitive that they're using folate to deliver an anti-folate drug.
...
I expect that, in the real world, cells that are methotrexate resistant(a folate analogue) would be resistant to targeting via folate transporters
I know it's off-topic but does anyone know if gravity on the Moon is enough to eliminate the problems associated with long-term zero g exposure?
Or do we just have to wait to find out?
What?
...
Did you also misread the headline as "Will Google buy Next?"
Are there any plans to submit seeds for preservation?
Planet Ark