Also, he is just trying to restore has slowly taken away by large corporations (like Disney, MPAA, RIAA - who do you think is buying off the politicians to take away fair use and the public domain?). No, it is not a revolution, but in these times, it sometimes seems like it.
If you have ever bothered to read Lessig's work or hear him speak, you would know that he is all in favor of people making a living off their creative works. You should really read The Future of Ideas. He sees, as the founding fathers seemed to, that to have innovation, protection should be limited. It was never intended to protect authors, much less their heirs (or companies) for, what is in a cultural sense, forever. Let them get real jobs and do their own creating. That is how cultures advance. What the Creative Commons is doing is attempting to restore some semblance of the public domain as it was originally proscribed.
It is March 2nd, not Feb 29th. No free shrimp for you (or any of us). I bet there was some collusion between NASA and LJS to rob the country of free shrimp;-) .
Because more damage was done in 48 hours than in 24, so it is cumulative in the rats tested. They speculated that this maybe the case in other organisms because the kind of damage done is double stranded DNA breaks that are harder to repair than single stranded nicks. They cited other research which suggests the mechanism for repairing this damage is to remove the damaged cell which is replaced by cell division. This is great, except for the fact that neurons don't replicate in this fashion so it could lead to the accumulation defects. Maybe the effect is small, maybe it varies highly with some individuals being more susceptible, or maybe neurons have alternative repair mechanism, but I think it is worth more research.
I'm not moving to a log cabin with no electricity anytime soon, but I'd like this research followed up with more experiments.
If you could get this headline published, it really would kill the effort. A few people calling in to talkshows with congress people asking them why they were considering measures to protect the producers of pornography would have them running away like frightened children.
I could see this really causing trouble for Fox News, How could they not report on the sleaziness of a porn story with out hurting their ultra-right wing congress buddies. Bill OReilley's might explode from the internal conflict, MUST REPORT SLEASY STORY -- CAN'T HURT REPUBLICANS -- AHHHHH! Oh, how am I kidding he'd just blame it on liberals.
to learn to say stuff like that with a straight face, because if I tried to say that in front of a crowd there is no way I would get through that statement with ROFL.
That said, I think the MS guy is right about iPods being the only mobile player that can play the m4ps are itunes (and now realplayer) and iPods (apple and hp). Of course, on my iPod I have aiffs, wavs, mp3s and m4as & m4ps. I wish it could play FLAC or some other loseless compression. Of course what the MS wants is for you to be able to play nothing but WMA, and Apple doesn't really care which of its supported formats you choose as long as you buy an iPod. You make the choice, you get locked in different ways - you have to take whichever you see as the lesser of two evils, or not play in this particular game.
I agree. In a previous thread in last year's vaporware awards Nominations for 2003 Vaporware Awards I suggested OQO for 2003, before finding that they won for 2002. They even cited that 2002 award as part of their press package. While I was seriously interested at the $1K price point, 2K is getting a little steep, and that is making the big assumption they ever release one, I am not getting my hopes up and will stick with my clie NX70v
I agree, plus if you would charge, then you need to track the revenue for tax purposes, and if I remember a cost analysis I saw on boingboing.net (for hotels, so not a 1 to 1 comparison) suggested the management involved for a pay service did not balance with what people were willing to pay, and the goodwill generated was worth the extra cost. I know I choose to frequent places I get a connection for free. I think you and the owner need to price it out on a monthly basis (including some advertising of the new service) and see if it meets the budget and run a trial service. Be sure to get the accountant involved to see how these business expenses impact the bottom line (depreciation and all that other stuff I don't understand).
I don't think IM is for everyone or every situation.
It works for me at my location. I am one of a dozen consultants stationed throughout my institution. With IM, I can find out who is available (sort of a virtual in/out board and get quick answers to questions. If it clear another medium is better (phone or e-mail) we switch. I can usually get "have you seen this problem" question with a URL answer in less than a minute. I have found for our group, that phone calls almost always lead to other things work related and personal stuff since it is sometimes as much as a week between times when we see each other.
Also, I am part of an organization that over-estimates the value of meetings and IM has been a great way for me to keep my productivity up while in meetings that I have no reason to attend, but can not refuse. Since I take notes on my laptop, so it rarely noticed.
Last for me, it is a fantastic resource when we are in meetings with vendors (In part, I deal with large products and it is not uncommon to have 10 of our people and almost as many vendor reps in the room). It is possible to work collectively to keep on top of what the vendor is saying and figure out what questions need to be asked.
There are times I turn off everything, but with IM, I can put up a sign saying, "In, but only contact if urgent." This way I know if there is something I need to get to right away. The phone and voicemail don't do that.
For my friends in cubes, IM is less distracting for their co-workers than phone or cube chats. So for short questions, even IMing a cube or two away can be better for productivity.
Don't they know some Yemeni men own Mars? This is old news, but three men from Yemen sued NASA for tresspassing as documented in this 1997 CNN story. According to the article these individuals have a 3000 year old claim on the red planet. What they do not realize is that my past life regressionist told me in a past life more than 5000 thousand years ago aliens gave Mars to me. Therefore, their claims are null and void.
I know a former manager of a sams club (another arm of the walmart evil empire). They receive extensive training on stopping union activity. I don't have a problem with that, but you might think spending the training dollars on keeping employees happy might go just as far. But what is going too far is upper management encouragement of store managements finding ways to get rid of employees they believe are involved in union organizing activity.
I shop around for good prices, but a good price is one that takes into account the full cost of production, allows for people manufacturing and selling to make reasonable profits so they can pay their employees a fair wage while at the same time producing a quality product. Walmart doesn't care about any of this. The people who shop at walmart don't realize that walmart's pricing and wage schemes will mean that they or their children will only able to afford to shop their (and just barely). If I remember correctly, the average store employee makes $13,000/yr -- it is just frightening.
Ethidium Bromide (EtBr) (Was Total nucleic acid)
on
Home DNA Sequencing
·
· Score: 1
While, I don't want it on my fingers that directly would not hurt you like an acid, but if it were to get into your system through absorption through the skin or, more likely, ingestion, it intercalates (wedges itself into) the double helix of the DNA strand. That is useful because ethidium bromide (etbr) fluoresces making it possible to visualize the bands of DNA being separated. It is bad for living systems because it can interfere with DNA replication causing mutations (thus it's designation as a mutagen) that could increase the likelihood of cancer, birth defects, etc.
But the last change I can find on their web site http://www.oqo.com was a link to the 2002 vaporware awards. You know it's bad when a company cites a vaporware articles about their product as product press. Maybe it is time to shut the web site down, huh?
I agree with your points, but as I remember the rare cutters are pretty expensive, but all my work is now in silico, so I am out of touch with pricing. I thought the same thing about the lambda included, but I am not sure what non-dangerous label could be used to get real bands (again, my distance from the lab is beginning to show). EtBr is not safe, SYBR green is less mutagenic, but would you trust a 10 yo with it? I see there is an other SYBR product called SYBR safe, with is not considered hazardous waste by the EPA, however anything that binds to DNA is a hazard at some level? All require UV light sources, and having received a couple gel illuminator tans in my younger, more stupid days, would worry about that, but it looks like they might have engineered the gel box to light only when the lid was on. If the ship date for the product was not Jan 16th, I'd be tempted to order it for my niece for the holidays and have her use it under my supervision. I think that would be the only way to get real answers.
Right on, there would be likely nothing but a smear, even cutting it up would result in a smear because the huge number of overlapping fragments, but the kit includes DNA stain -- fabricated to mimic real DNA -- so I am guessing you will always get the same pattern. I suppose you could run it out on the gel, take a sample from the lane, and run that out in a lower %age agarose gel to separate things out.
However, this is a crude extract with no purification or isolation. Fingerprinting this kind of prep is worthless to answer questions other than is there nucleic acids in the sample unless they are including some sort of probe (highly unlikely). Fingerprinting entire genomes of multichromosomal organisms would not be something worth doing (beyond the gee-whiz factor) unless you move into doing blots, or if you worked with entities with single chromosomes such as bacteria or mitochondrial DNA. They include lambda DNA, maybe that let's them do a fingerprint, maybe with a double digest to do some mapping.
Given the fact that it appears that the DNA stain seems to be responsible for the pattern seen- the good news for parents fearful that Jane or Johnny might discover something about her/his parentage, everyone in the world will look like they have identical patterns- unless the kid is smart enough to figure out that it might mean the parents might be a little too closely related.
Which machine would you take out the box and hook up without worrying too much about being hacked. It's not Windows. The situation has improved, but one vulnerability (not an exploit) compared to how many WinOS exploits? Come on, my grandma's getting a Mac.
Good points, let's assume the USPTO personnel are making a good faith effort, I would hope that they would welcome this kind of database (what faith I have in people being of good will, huh?).
I don't fully understand the relationship between prior art and issuing patents, and I am sure that's the way the attorneys like it.
IANAPAE (... either), so how much prior art does it take to say you can't patent an idea? Is there a need to demonstrate multiple instances of prior art?
Also is there a relationship in timing? If you and I invent telephone-like devices in the same general time period, is it the first one to get their documents in who gets the patent, or is it the person who can demonstrate they had the idea first (I thought it was the former, but what do I know?)?
Since it does not make sense to reinvent the wheel (unless you want to patent it) I wonder if this is something the Creative Commons could register if this would be an effective means of protecting ideas.
Can you patent an idea and then release it into the public domain or put it under a Creative Commons license (or something like it)? It seems like this might head off some of the prior art arguements, and even if some other entity breaks the patent because of other prior art, it still is better than it moving into a single group's hands. I know it is more work, but I am tied of getting screwed-over because someone comes up with something "innovative*".
Just wondering....
* Innovative (MS, SCO, et. al definition) - scouring the world for ideas for which they can claim ownership.
I third this recommendation. I would recommend a nikon FM (or FE) series over the K1000 any day. On the used market, you should be able to find one at a reasonable price. When I worked in the camera trade I almost never saw a dead FM/E unless it was a pretty clear case of abuse.
Remember ALWAYS put the camera in the bag in the car. Do not leave on the roof.
I was just looking for a place to buy some for the tank in my lab. We have zebrafish researchers down the hall how thought the idea was silly. Since they would not make them for me, I need to go buy them...bastards.
I am worried about the SCO lawyers
on
SCO News Roundup
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· Score: 2, Funny
I am worried that SCO's lawyers are going to be out of luck, poor guys only get 1,000,000 dollars and a capital gains loss when SCO tanks. How will they ever survive on that. They might not be able to get that new 5 series BMW.
or get you on those gravy-train corporate boards. There should be a disclosure statement of who he and the publication's beholding to.
To be fair, he is right, free software may not cost anything is not free, but his own example, webct, costs a hell of a lot in internal support, that's on top of a 3 fold cost increase in licensing fees in recent years. I wonder if he is trying to justify why he and his group are not participating in open source CMS (course management systems) efforts and ponying up a 6 or 7 figure license fee, and then finding internal funds for running and supporting it. That money would pay a lot of professional programmers' salaries.
There are dangers of relying on free software, especially it is a fragile project, but who says the WebCT will be around in a few years. And, do you think if that happens you will have a choice between changing products or trying to maintain the product yourself? I doubt it.
It's an interesting piece, but will do more harm them good, but maybe that is what he wanted. I can see those board offers rolling in.
Slashdot Mirror
Also, he is just trying to restore has slowly taken away by large corporations (like Disney, MPAA, RIAA - who do you think is buying off the politicians to take away fair use and the public domain?). No, it is not a revolution, but in these times, it sometimes seems like it.
If you have ever bothered to read Lessig's work or hear him speak, you would know that he is all in favor of people making a living off their creative works. You should really read The Future of Ideas. He sees, as the founding fathers seemed to, that to have innovation, protection should be limited. It was never intended to protect authors, much less their heirs (or companies) for, what is in a cultural sense, forever. Let them get real jobs and do their own creating. That is how cultures advance. What the Creative Commons is doing is attempting to restore some semblance of the public domain as it was originally proscribed.
It is March 2nd, not Feb 29th. No free shrimp for you (or any of us). I bet there was some collusion between NASA and LJS to rob the country of free shrimp ;-) .
Great letter! Of course, it relies on congress seeing hypocrisy as a bad thing. Unfortunately, it is often par for the course.
Because more damage was done in 48 hours than in 24, so it is cumulative in the rats tested. They speculated that this maybe the case in other organisms because the kind of damage done is double stranded DNA breaks that are harder to repair than single stranded nicks. They cited other research which suggests the mechanism for repairing this damage is to remove the damaged cell which is replaced by cell division. This is great, except for the fact that neurons don't replicate in this fashion so it could lead to the accumulation defects. Maybe the effect is small, maybe it varies highly with some individuals being more susceptible, or maybe neurons have alternative repair mechanism, but I think it is worth more research.
I'm not moving to a log cabin with no electricity anytime soon, but I'd like this research followed up with more experiments.
If you could get this headline published, it really would kill the effort. A few people calling in to talkshows with congress people asking them why they were considering measures to protect the producers of pornography would have them running away like frightened children. I could see this really causing trouble for Fox News, How could they not report on the sleaziness of a porn story with out hurting their ultra-right wing congress buddies. Bill OReilley's might explode from the internal conflict, MUST REPORT SLEASY STORY -- CAN'T HURT REPUBLICANS -- AHHHHH! Oh, how am I kidding he'd just blame it on liberals.
to learn to say stuff like that with a straight face, because if I tried to say that in front of a crowd there is no way I would get through that statement with ROFL.
That said, I think the MS guy is right about iPods being the only mobile player that can play the m4ps are itunes (and now realplayer) and iPods (apple and hp). Of course, on my iPod I have aiffs, wavs, mp3s and m4as & m4ps. I wish it could play FLAC or some other loseless compression. Of course what the MS wants is for you to be able to play nothing but WMA, and Apple doesn't really care which of its supported formats you choose as long as you buy an iPod. You make the choice, you get locked in different ways - you have to take whichever you see as the lesser of two evils, or not play in this particular game.
I agree. In a previous thread in last year's vaporware awards Nominations for 2003 Vaporware Awards I suggested OQO for 2003, before finding that they won for 2002. They even cited that 2002 award as part of their press package. While I was seriously interested at the $1K price point, 2K is getting a little steep, and that is making the big assumption they ever release one, I am not getting my hopes up and will stick with my clie NX70v
I agree, plus if you would charge, then you need to track the revenue for tax purposes, and if I remember a cost analysis I saw on boingboing.net (for hotels, so not a 1 to 1 comparison) suggested the management involved for a pay service did not balance with what people were willing to pay, and the goodwill generated was worth the extra cost. I know I choose to frequent places I get a connection for free. I think you and the owner need to price it out on a monthly basis (including some advertising of the new service) and see if it meets the budget and run a trial service. Be sure to get the accountant involved to see how these business expenses impact the bottom line (depreciation and all that other stuff I don't understand).
I don't think IM is for everyone or every situation.
It works for me at my location. I am one of a dozen consultants stationed throughout my institution. With IM, I can find out who is available (sort of a virtual in/out board and get quick answers to questions. If it clear another medium is better (phone or e-mail) we switch. I can usually get "have you seen this problem" question with a URL answer in less than a minute. I have found for our group, that phone calls almost always lead to other things work related and personal stuff since it is sometimes as much as a week between times when we see each other.
Also, I am part of an organization that over-estimates the value of meetings and IM has been a great way for me to keep my productivity up while in meetings that I have no reason to attend, but can not refuse. Since I take notes on my laptop, so it rarely noticed.
Last for me, it is a fantastic resource when we are in meetings with vendors (In part, I deal with large products and it is not uncommon to have 10 of our people and almost as many vendor reps in the room). It is possible to work collectively to keep on top of what the vendor is saying and figure out what questions need to be asked.
There are times I turn off everything, but with IM, I can put up a sign saying, "In, but only contact if urgent." This way I know if there is something I need to get to right away. The phone and voicemail don't do that.
For my friends in cubes, IM is less distracting for their co-workers than phone or cube chats. So for short questions, even IMing a cube or two away can be better for productivity.
Like I said, it works for me, YMMV
Don't they know some Yemeni men own Mars? This is old news, but three men from Yemen sued NASA for tresspassing as documented in this 1997 CNN story. According to the article these individuals have a 3000 year old claim on the red planet. What they do not realize is that my past life regressionist told me in a past life more than 5000 thousand years ago aliens gave Mars to me. Therefore, their claims are null and void.
I know a former manager of a sams club (another arm of the walmart evil empire). They receive extensive training on stopping union activity. I don't have a problem with that, but you might think spending the training dollars on keeping employees happy might go just as far. But what is going too far is upper management encouragement of store managements finding ways to get rid of employees they believe are involved in union organizing activity.
I shop around for good prices, but a good price is one that takes into account the full cost of production, allows for people manufacturing and selling to make reasonable profits so they can pay their employees a fair wage while at the same time producing a quality product. Walmart doesn't care about any of this. The people who shop at walmart don't realize that walmart's pricing and wage schemes will mean that they or their children will only able to afford to shop their (and just barely). If I remember correctly, the average store employee makes $13,000/yr -- it is just frightening.
While, I don't want it on my fingers that directly would not hurt you like an acid, but if it were to get into your system through absorption through the skin or, more likely, ingestion, it intercalates (wedges itself into) the double helix of the DNA strand. That is useful because ethidium bromide (etbr) fluoresces making it possible to visualize the bands of DNA being separated. It is bad for living systems because it can interfere with DNA replication causing mutations (thus it's designation as a mutagen) that could increase the likelihood of cancer, birth defects, etc.
But the last change I can find on their web site http://www.oqo.com was a link to the 2002 vaporware awards. You know it's bad when a company cites a vaporware articles about their product as product press. Maybe it is time to shut the web site down, huh?
I agree with your points, but as I remember the rare cutters are pretty expensive, but all my work is now in silico, so I am out of touch with pricing. I thought the same thing about the lambda included, but I am not sure what non-dangerous label could be used to get real bands (again, my distance from the lab is beginning to show). EtBr is not safe, SYBR green is less mutagenic, but would you trust a 10 yo with it? I see there is an other SYBR product called SYBR safe, with is not considered hazardous waste by the EPA, however anything that binds to DNA is a hazard at some level? All require UV light sources, and having received a couple gel illuminator tans in my younger, more stupid days, would worry about that, but it looks like they might have engineered the gel box to light only when the lid was on. If the ship date for the product was not Jan 16th, I'd be tempted to order it for my niece for the holidays and have her use it under my supervision. I think that would be the only way to get real answers.
Right on, there would be likely nothing but a smear, even cutting it up would result in a smear because the huge number of overlapping fragments, but the kit includes DNA stain -- fabricated to mimic real DNA -- so I am guessing you will always get the same pattern. I suppose you could run it out on the gel, take a sample from the lane, and run that out in a lower %age agarose gel to separate things out.
However, this is a crude extract with no purification or isolation. Fingerprinting this kind of prep is worthless to answer questions other than is there nucleic acids in the sample unless they are including some sort of probe (highly unlikely). Fingerprinting entire genomes of multichromosomal organisms would not be something worth doing (beyond the gee-whiz factor) unless you move into doing blots, or if you worked with entities with single chromosomes such as bacteria or mitochondrial DNA. They include lambda DNA, maybe that let's them do a fingerprint, maybe with a double digest to do some mapping.
Given the fact that it appears that the DNA stain seems to be responsible for the pattern seen- the good news for parents fearful that Jane or Johnny might discover something about her/his parentage, everyone in the world will look like they have identical patterns- unless the kid is smart enough to figure out that it might mean the parents might be a little too closely related.
Which machine would you take out the box and hook up without worrying too much about being hacked. It's not Windows. The situation has improved, but one vulnerability (not an exploit) compared to how many WinOS exploits? Come on, my grandma's getting a Mac.
Good points, let's assume the USPTO personnel are making a good faith effort, I would hope that they would welcome this kind of database (what faith I have in people being of good will, huh?).
I don't fully understand the relationship between prior art and issuing patents, and I am sure that's the way the attorneys like it. IANAPAE (... either), so how much prior art does it take to say you can't patent an idea? Is there a need to demonstrate multiple instances of prior art?
Also is there a relationship in timing? If you and I invent telephone-like devices in the same general time period, is it the first one to get their documents in who gets the patent, or is it the person who can demonstrate they had the idea first (I thought it was the former, but what do I know?)?
Since it does not make sense to reinvent the wheel (unless you want to patent it) I wonder if this is something the Creative Commons could register if this would be an effective means of protecting ideas.
Can you patent an idea and then release it into the public domain or put it under a Creative Commons license (or something like it)? It seems like this might head off some of the prior art arguements, and even if some other entity breaks the patent because of other prior art, it still is better than it moving into a single group's hands. I know it is more work, but I am tied of getting screwed-over because someone comes up with something "innovative*".
Just wondering....
* Innovative (MS, SCO, et. al definition) - scouring the world for ideas for which they can claim ownership.
I third this recommendation. I would recommend a nikon FM (or FE) series over the K1000 any day. On the used market, you should be able to find one at a reasonable price. When I worked in the camera trade I almost never saw a dead FM/E unless it was a pretty clear case of abuse. Remember ALWAYS put the camera in the bag in the car. Do not leave on the roof.
To understand the concept, you should think of "free" as in ``free speech,'' not as in "free beer.'' ;-)
I was just looking for a place to buy some for the tank in my lab. We have zebrafish researchers down the hall how thought the idea was silly. Since they would not make them for me, I need to go buy them...bastards.
I am worried that SCO's lawyers are going to be out of luck, poor guys only get 1,000,000 dollars and a capital gains loss when SCO tanks. How will they ever survive on that. They might not be able to get that new 5 series BMW.
or get you on those gravy-train corporate boards. There should be a disclosure statement of who he and the publication's beholding to. To be fair, he is right, free software may not cost anything is not free, but his own example, webct, costs a hell of a lot in internal support, that's on top of a 3 fold cost increase in licensing fees in recent years. I wonder if he is trying to justify why he and his group are not participating in open source CMS (course management systems) efforts and ponying up a 6 or 7 figure license fee, and then finding internal funds for running and supporting it. That money would pay a lot of professional programmers' salaries. There are dangers of relying on free software, especially it is a fragile project, but who says the WebCT will be around in a few years. And, do you think if that happens you will have a choice between changing products or trying to maintain the product yourself? I doubt it. It's an interesting piece, but will do more harm them good, but maybe that is what he wanted. I can see those board offers rolling in.