... but in the hands of a professional your concern is misguided.
My point being that a technically difficult test, one that requires a significant amount of specialty training, isn't ideal for something that may end up being a screening test (where you are testing a large number of people, most of which won't have the problem). That also is an issue with PET scans since they're technically demanding and complex.
The utility of having a fairly specific test for Alzheimer's, on that doesn't require brain biopsy - the ultimate bad screening test, will hopefully allow researchers to come up with something more suitable for a generalized test.
It's really the same issue as a colonoscopy for colon cancer screening. It's sensitive and specific but a pain in the ass (so to speak).
That happens, but it is rare. But because of the potential numbers of people who would want the test, the difficulty of doing a lumbar puncture (spinal tap) on persons who have arthritis in the back (very common among us ancient folk), are of the supersized persuasion, or have other reasons to dissuade themselves, I don't think this is going to be the ultimate test.
Instead it will serve as a proxy to allow simpler tests to be developed. TFA also notes that PET scans are fairly accurate. These are available at many larger medical centers but are also pretty pricey and technically complex.
This is also not the first time that lumbar punctures for beta amyloid have been used to diagnose Alzheimer's. And finally, the abstract of the original article for your viewing pleasure.
It's only speculation, but I suspect that they got tired of me and just let the wireless router go into disrepair. Oh well.
Man, that's the saddest story I've heard on Slashdot all week. Taco Bell employees essentially throw you out because they don't like you. How low can you go?
N, it's not so 'simple'. Although there is a tendency towards fewer environmental allergies in people exposed to a larger mix of allergens ('dirt and stuff') it's by no means a binary thing. Allergic reactions are complex and multifactorial. I don't think the driving force behind allergic responses is a Darwinian selection sort of thing (remember, not EVERYTHING is a selection factor). It may well be that the inherent complexity of the challenge - response systems in the immune system leads to 'problems'. Although the immune system is a hugely functional piece of kit (try living without one for a while) it is also responsible for many human diseases when it goes out of whack.
So let your kids play out in the back with the horses and hay but don't be surprised if they get celiac disease. That's apples and oranges. Or Yugos and Hummers. (Added to preempt the inevitable request for an automotive analogy.)
Just a idea. Sit down. Have a drink. Now don't get mad at me or all stressed out, I know it's hard to deal with new things. Just consider to concept at least:
All you need to do to blow out the storage capacity of SSDs is a video camera. If you are persistent enough, even a still camera is enough.
Look, I've got a 250 GB SSD and a one terabyte rotating platter hard drive on my 3 year old MacBook Pro. I'm one happy camper. The SSD makes the MBP fly along - not nearly as fast as my MacPro but so much more responsive than any laptop I've used before. The big, albiet relatively slow HD holds most of my still photos, and enough video to keep me entertained for months. The SSD has really sped up Photoshop. FinalCut is perhaps 20 - 30% faster.
The near term future, IMHO, is going to be this sort of thing - using smaller SSDs for applications and scratch and big honker "slow" drives for storage.
Ah, the well formed, cogent, intellectual argument. You don't like my thesis, so you have to express an ad hominem. Truly impressive, sir. Well played.
I pretty much agree with your point, but would like to point out that no other country is or has been involved in as many large scale, outright wars as we are, at the frequency we are.
Huh? Your view of history is pretty narrow. Perhaps in the 20th Century the US has been involved in more wars that others (often as a defensive position, ie, WWI, WW2, Korea) but the history of mankind has been that of war for thousands and thousands of years.
This is reality, not the Federation of Planets. Get used to it.
Slashdot Mirror
My point being that a technically difficult test, one that requires a significant amount of specialty training, isn't ideal for something that may end up being a screening test (where you are testing a large number of people, most of which won't have the problem). That also is an issue with PET scans since they're technically demanding and complex.
The utility of having a fairly specific test for Alzheimer's, on that doesn't require brain biopsy - the ultimate bad screening test, will hopefully allow researchers to come up with something more suitable for a generalized test.
It's really the same issue as a colonoscopy for colon cancer screening. It's sensitive and specific but a pain in the ass (so to speak).
Such a dreamer you are.
That happens, but it is rare. But because of the potential numbers of people who would want the test, the difficulty of doing a lumbar puncture (spinal tap) on persons who have arthritis in the back (very common among us ancient folk), are of the supersized persuasion, or have other reasons to dissuade themselves, I don't think this is going to be the ultimate test.
Instead it will serve as a proxy to allow simpler tests to be developed. TFA also notes that PET scans are fairly accurate. These are available at many larger medical centers but are also pretty pricey and technically complex.
This is also not the first time that lumbar punctures for beta amyloid have been used to diagnose Alzheimer's. And finally, the abstract of the original article for your viewing pleasure.
Man, that's the saddest story I've heard on Slashdot all week. Taco Bell employees essentially throw you out because they don't like you. How low can you go?
You need a hug.
So you're saying that Santa Claus is real? That Google is Santa Claus?
This could get complicated.
I'm not sure this is the time or place to break it to you - but that's no cupholder.
Kids these days. Don't know anything.
Grrrr. I hate that sort of thing. I can't even blame it on kdawson (this time). So much for proofing.
Sometimes you win, sometimes you loose.
N, it's not so 'simple'. Although there is a tendency towards fewer environmental allergies in people exposed to a larger mix of allergens ('dirt and stuff') it's by no means a binary thing. Allergic reactions are complex and multifactorial. I don't think the driving force behind allergic responses is a Darwinian selection sort of thing (remember, not EVERYTHING is a selection factor). It may well be that the inherent complexity of the challenge - response systems in the immune system leads to 'problems'. Although the immune system is a hugely functional piece of kit (try living without one for a while) it is also responsible for many human diseases when it goes out of whack.
So let your kids play out in the back with the horses and hay but don't be surprised if they get celiac disease. That's apples and oranges. Or Yugos and Hummers. (Added to preempt the inevitable request for an automotive analogy.)
In this economy, brother, you're not going to retire at all. You'll be lucky to get out of Cleveland, much less Earth's gravity well.
Cranky fellow. Missed the early stock options, did we?
The vast majority of (at least US) drivers certainly act like they found a driver's license at the bottom of their Cocoa Puffs box.
Your folks gave you Rocket Propelled Grenades as a kid?
Did you grow up in Afghanistan?
Yes, but the other 99% do.
Just a idea. Sit down. Have a drink. Now don't get mad at me or all stressed out, I know it's hard to deal with new things. Just consider to concept at least:
Read the Fucking Article.
Your Reality Distortion Field is getting a bit weak. Time to head out to your local Apple store and buy something new and shiny to refresh the Field.
Then you will feel better.
I'm gonna sit back and watch a bunch of male geeks get all teary eyed about some robot.
"Just my allergies, I hate summer".
They've just invented beer? Not terribly impressive, I'd say.
I think he was talking about Google, not Microsoft.
Look, I've got a 250 GB SSD and a one terabyte rotating platter hard drive on my 3 year old MacBook Pro. I'm one happy camper. The SSD makes the MBP fly along - not nearly as fast as my MacPro but so much more responsive than any laptop I've used before. The big, albiet relatively slow HD holds most of my still photos, and enough video to keep me entertained for months. The SSD has really sped up Photoshop. FinalCut is perhaps 20 - 30% faster.
The near term future, IMHO, is going to be this sort of thing - using smaller SSDs for applications and scratch and big honker "slow" drives for storage.
While you're at it can you work on Firefly?
Somebody is doing something very, very wrong here.
Let me guess, you use GIMP.
Ah, the well formed, cogent, intellectual argument. You don't like my thesis, so you have to express an ad hominem. Truly impressive, sir. Well played.
Huh? Your view of history is pretty narrow. Perhaps in the 20th Century the US has been involved in more wars that others (often as a defensive position, ie, WWI, WW2, Korea) but the history of mankind has been that of war for thousands and thousands of years.
This is reality, not the Federation of Planets. Get used to it.
Heinlein, Starship troopers, 1959
Easier still - infinity is pretty damned big.