I am not sure you are right. I thought phase I trials were always done on healthy individuals to find a basic tolerable dose, not a maximum tolerable dose (which I think is phase II). And phase III trials would mean testing on diseased patients, in this case, I guess it means receiving the vaccine and then be injected with ebola. I am not sure they would go that far here. They might vaccine thousands of people in potentially infected areas and see if any of the vaccinated locals get ebola. Anyway, vaccines are not the same as drugs, so the trial phases might be different.
Generaly, only north americans drink milk during their mature life. You've never been to the Netherlands! The huge majority (I would guess 90%) of Dutch drink milk during lunch. I have even been to places where there was only milk to drink, not even water!
I guess the trick is easy, just eat a balanced diet. (but what is balance ?;-) That's easy. A balance diet is a bit of everything.
You don't need Montignac's books, you just need to eat a reasonable amount of varied food.
anti-French xenophobia is fashionable. It used to be anti-black, anti-jew,... but now the same stupid rednecks are anti-french, anti-chinese, anti-german,... It's really pathetic.
Not that it really matters, but it's actually two Russians and a Brit Do not forget that the poster of the news is quoting "Fox News", Proudly sponsored by the US government propaganda services!
A link to google news would have been more appropriate.
I just wish we had a european version of these games, with real cars! It was great to play the gateway with cars that I knew and that can turn (not like in VC). Other than that the game was pretty boring.
Maybe these games could be adapted to your favourite town. You could have the London, Paris, Roma versions.
From the article: (Imagine that, though: a computer that would glow different colors based on how much of its processing power was being used. When it turned red, you'd know that a crash was imminent.)
The Red Computer of Death then. I am not sure why your computer should crash if too much processing power is used. Maybe a combination of AMD procs and Windows?
Replace "criminal" with "terrorist" and you see how ridiculous your counter argument becomes. What do you mean? Everyone should have guns to protect themselves from terrorists?
lower crime rates, nearly as low as Switzerland I have been to the USA 4 times. I was close to being shot at twice (by criminals). I live in Europe and I have never been shot at. I don't even know someone that has been shot at in Europe! People in the USA don't even realise how much safer the EU is.
Sure, we should make guns illegal to ensure that only criminals have them.
This reasoning has been debunked several decades ago. Replace gun by (grenade/sub machine gun/rocket launcher) and you see how ridiculous it becomes. In most civilised countries only the criminals and the police have guns. And these countries have a much lower crime and murder rate than the USA.
Learning is fun. But still, an MBA! There are a million different studies that are more interesting. One of my colleagues resigned to do an MBA. I still don't understand why?
4 Freedom to copy and distribute modifications. Again, the distribution has to be in source and binary code,... The GPL only requires that you release the source code, not binaries.
I have no reason to doubt that the French have a lovely distribution network. And believe me, they pay dearly for it in their electric bills and taxes.
No I don't believe you. As far as I know, France has one of the lowest electricity prices in Europe, and moreover exports quite a large size of it to neighbouring country. About 80% of it is made by nuclear central stations.
You Brits don't even use the Euro. Calling yourself a member of the EU is a bit of a stretch... "here join this... and use the common currency... us? no way man. GBP rule!"
You are an asshole. With such reactions, I am not surprised some Brits hesitate going for the Euro.
You should not bring Chinese morality into this, since US researchers have tried this too. from the WP article: Although scientists in Massachusetts had previously mixed human cells and cow eggs in a similar attempt to make hybrid embryos as a source of stem cells, those experiments were not successful.
Secondly, this was done to produce stem cells and not out of morbid curiosity. Please, I know this is/., but RTFA!
You are right. It is a very difficult thing to know if a drug will work for everyone or for only a few people and how well it works. On top of this there is also the problem of testing combinations of drugs as some cocktails can be lethal.
Let's hope that with the advances in human genomics, doctors will be able to DNA-test the efficacy of drugs on patients before giving them the drugs. We are not so far away from that, I'd say 5 years.
Drugs companies actually spend far more on marketing than they do on R&D, which includes approvals. How much of that marketing is really necessary - unless, of course, the drugs aren't really as effective as they claim?
The thing people usually misunderstand about drug approval is that the results of the clinical tests are open to scrutiny. If the drugs are not effective, the FDA can (and does) not approve them. Having said that, pharmaceutical companies spend way too much money on "lobbying" doctors. The usual budget rundown is: 1/3 R&D, 1/3 infrastructure, 1/3 Marketing and sales. Of the 1/3 R&D, 1/3 goes to research, which makes the pharmaceutical industry the industry that spends the most in research.
Slashdot Mirror
I am not sure you are right. I thought phase I trials were always done on healthy individuals to find a basic tolerable dose, not a maximum tolerable dose (which I think is phase II).
And phase III trials would mean testing on diseased patients, in this case, I guess it means receiving the vaccine and then be injected with ebola. I am not sure they would go that far here. They might vaccine thousands of people in potentially infected areas and see if any of the vaccinated locals get ebola.
Anyway, vaccines are not the same as drugs, so the trial phases might be different.
There were murmurs of agreement.
I think the writer misunderstood the murmurs!
Not all weapons are equal. Biological weapons have the potential of destroying much of this planet.
What if other countries do the same to "protect themselves from terrorists" too? Some probably do.
Aren't we all in deep shit then?
Generaly, only north americans drink milk during their mature life.
;-)
You've never been to the Netherlands! The huge majority (I would guess 90%) of Dutch drink milk during lunch. I have even been to places where there was only milk to drink, not even water!
I guess the trick is easy, just eat a balanced diet. (but what is balance ?
That's easy. A balance diet is a bit of everything.
You don't need Montignac's books, you just need to eat a reasonable amount of varied food.
the the
It means MS is going back to the 80's.
anti-French xenophobia is fashionable. It used to be anti-black, anti-jew, ... but now the same stupid rednecks are anti-french, anti-chinese, anti-german, ...
It's really pathetic.
Do not forget that the poster of the news is quoting "Fox News", Proudly sponsored by the US government propaganda services!
A link to google news would have been more appropriate.
I just wish we had a european version of these games, with real cars! It was great to play the gateway with cars that I knew and that can turn (not like in VC). Other than that the game was pretty boring.
Maybe these games could be adapted to your favourite town. You could have the London, Paris, Roma versions.
From the article:
(Imagine that, though: a computer that would glow different colors based on how much of its processing power was being used. When it turned red, you'd know that a crash was imminent.)
The Red Computer of Death then. I am not sure why your computer should crash if too much processing power is used. Maybe a combination of AMD procs and Windows?
I've always wondered how fast/accurately they skeletons react to human initiated/controlled motion
Grandpa to grandma: Come on! Let's put our exo-skeletons and have high-speed sex!
Scary, but I would not mind seeing the movie....
I remember when in the mid-90's we used to call playing doom and later quake : Network testing
Replace "criminal" with "terrorist" and you see how ridiculous your counter argument becomes.
What do you mean? Everyone should have guns to protect themselves from terrorists?
lower crime rates, nearly as low as Switzerland
I have been to the USA 4 times. I was close to being shot at twice (by criminals). I live in Europe and I have never been shot at. I don't even know someone that has been shot at in Europe! People in the USA don't even realise how much safer the EU is.
Sure, we should make guns illegal to ensure that only criminals have them.
This reasoning has been debunked several decades ago. Replace gun by (grenade/sub machine gun/rocket launcher) and you see how ridiculous it becomes. In most civilised countries only the criminals and the police have guns. And these countries have a much lower crime and murder rate than the USA.
Learning is fun. But still, an MBA! There are a million different studies that are more interesting. One of my colleagues resigned to do an MBA. I still don't understand why?
Well, quite a few years ago, they ran out of odd numbers, so they started using even numbers!
Seriously, even -> stable, odd -> devel.
4 Freedom to copy and distribute modifications. Again, the distribution has to be in source and binary code,...
The GPL only requires that you release the source code, not binaries.
I have no reason to doubt that the French have a lovely distribution network. And believe me, they pay dearly for it in their electric bills and taxes.
No I don't believe you. As far as I know, France has one of the lowest electricity prices in Europe, and moreover exports quite a large size of it to neighbouring country. About 80% of it is made by nuclear central stations.
You Brits don't even use the Euro. Calling yourself a member of the EU is a bit of a stretch... "here join this... and use the common currency... us? no way man. GBP rule!"
You are an asshole. With such reactions, I am not surprised some Brits hesitate going for the Euro.
Someone from Euro-land.
Funniest remark I have heard on /. for ages!
You should not bring Chinese morality into this, since US researchers have tried this too. from the WP article:
/., but RTFA!
Although scientists in Massachusetts had previously mixed human cells and cow eggs in a similar attempt to make hybrid embryos as a source of stem cells, those experiments were not successful.
Secondly, this was done to produce stem cells and not out of morbid curiosity. Please, I know this is
knowing how rabbits multiply
New Chinese policy: Only one baby rabbit per couple!
mix of DNA from both human and rabbit
Well, not exactly. The cell DNA was human. Only the mitochondrial DNA was from rabbit.
You are right. It is a very difficult thing to know if a drug will work for everyone or for only a few people and how well it works. On top of this there is also the problem of testing combinations of drugs as some cocktails can be lethal.
Let's hope that with the advances in human genomics, doctors will be able to DNA-test the efficacy of drugs on patients before giving them the drugs. We are not so far away from that, I'd say 5 years.
Drugs companies actually spend far more on marketing than they do on R&D, which includes approvals. How much of that marketing is really necessary - unless, of course, the drugs aren't really as effective as they claim?
The thing people usually misunderstand about drug approval is that the results of the clinical tests are open to scrutiny. If the drugs are not effective, the FDA can (and does) not approve them.
Having said that, pharmaceutical companies spend way too much money on "lobbying" doctors. The usual budget rundown is: 1/3 R&D, 1/3 infrastructure, 1/3 Marketing and sales. Of the 1/3 R&D, 1/3 goes to research, which makes the pharmaceutical industry the industry that spends the most in research.