He goes onto a site and begins with a bait picture (which is a lie) to entice someone into a private conversation and then publishes the response.
Anyone who thinks this is good natured humor knows little of human nature. This activity is particularly nasty because it often entices the dark side of owns nature to come out and then lays shame on them so this fucking worthless blogger can have something to write about. He was not conducting and experiment to prove any hypothesis, he was just looking for something to write about because his mind is very uncreative.
Candid CAMERA THAT WAS FUNNY BECAUSE IN THE END THE PARTICIPANTS WERE LAUGHING TO. HERE THAT IS NOT THE CASE
you keep saying that but u do not explain why? Glider is a completely useless program without the code of WoW. In other words the only thing it does is mine the data generated by the client program WoW. The strech is not to far for me to see that they are infringing on WoW copyrighted code. Please explain to me how they/glider are not?
Since you do not play you would not understand....but alas your comments imply you have played.
Leveling is part of the game. By your logic what is the point of rolling dice in Monopoly? Mabe we should just get a random number generator and let it play till all property is bought. In WoW Leveling is part of the game and while instances are also part of the game so are BGs. The bot allows for PvP players to develop far faster than rules allow. to the players that do there own levling the is a pratical screw in the ass. Also the bots will change distribution of resources so that it may take non cheaters longer. AND THAT IS NOT FAIR
I really doubt that and you are being a bit over the top. The legal arguement would never stand if the hackers were modifing freeware. But this is a paid service where the code is subverting the pleasure of customers who pay to use the online community. The hackware is specifically designed to subvert the rules of play. Do u deny that?
As for the free world, I am WAY more worried about Homeland security than of the legal actions of Blizzard to protect its online community from cheaters.
agent for whom??? I am just a game player who does not cheat and wishes to play with others that do not cheat. I will take from your snide comment that you see nothing wrong with coders writing code that will subvert MY PLEASURE that I paid good money for. You would make a good manager at Walmart Mr Mann
you are now rationalizing why it is okay to cheat.
BTW, your argument stinks the kid at home DID THE MINING himself , the bot user did not. How difficult the task is does not matter and is known as a "red Herring"
So do you think it is OK to cheat? Do You like to play with other players That are cheating? I do not pay ~15 bucks a month to have to pay a computer game I cheat at? I have played PS2, PS3, Wii and a few others and I have NEVER used a cheat code. I consider them repulsive. also why whould I spend money on a game I cheat at? I could just as well save my money and get a deck of cards and just cheat at solitaire. I do not fault Blizzrd for attempting to do what they are doing I just wish they did not have to. And Yes what they/blizzard is doing is an impossible task imho
In other words, legally say "Blizzard.... Go To Hell."
Well are you not a swell guy or what???
So what do you say to the guy that is NOT cheating? "Hey that is your problem, you oughta cheat too"
This code sucks and people that develop it suck as well. They are people that do not believe rules are for them. Why don't they just go write ther own Open source versions of WoW and play with themselves. I want to play the game WITHOUT having to resort to cheat.
As revealed by the indictment, the "unauthorized access" results from various violations of MySpace's terms of service.
I'm no expert on the Computer Fraud and Abuse Act (CFAA), but at least one court has found that violation of a company's terms of service constitutes "unauthorized access" for purposes of the Act. See America Online, Inc. v. LCGM, Inc., 46 F. Supp. 2d 444, 450-51 (E.D. Va. 1998).
The CFAA makes it illegal to, among other things, "intentionally access[] a computer without authorization or exceed[] authorized access, and thereby obtain[] . . . information from any protected computer if the conduct involved an interstate or foreign communication." 18 U.S.C. 1030(a)(2)(C).
The punishment for violating this subsection of the CFAA is a fine or up to 5 years imprisonment if "the offense was committed in furtherance of any criminal or tortious act in violation of the Constitution or laws of the United States or of any State." Id. (c)(2)(B)(ii). (Otherwise there needs to be some sort of pecuniary gain or the information gained needs to be worth $5,000 or more.)
So, how did Drew allegedly violate the CFAA? MySpace's terms of service forbid you from lying to MySpace or using your account to harrass other users, obtain personal information from minors, posting photos of people without their consent, etc. Drew broke all of these terms when, among other things, she registered as a teenage boy, got personal information from the 13 year old victim, and posted a picture of a teenage boy without his consent.
Because she violated MySpace's terms of service, her access to MySpace's servers was "unauthorized access." Her unauthorized access involved an "interstate . . . communication" because MySpace's servers are in California and Drew accessed them from a computer in Missouri.
Drew allegedly used her account and the information she received to harass the victim to the point where it constituted the tort of intentional infliction of emotional distress, a well-recognized tort in Missouri (and, to my knowledge, recognized in all states). See, e.g., Central Missouri Elec. Co-op. v. Balke, 119 S.W.3d 627, 636 (Mo. Ct. App. 2003) ("To recover for intentional infliction of emotional distress, the [plaintiff] must show (1) the defendant's conduct was extreme and outrageous; (2) the defendant acted intentionally or recklessly; and (3) the defendant's conduct caused extreme emotional distress resulting in bodily harm."). Thus, her unauthorized access "was committed in furtherance of any . . . tortious act in violation of the . . . laws of the . . . any State."
Now, you could argue that the indictment may be an abuse of prosecutorial discretion, but I don't see how you can argue that this indictment is frivolous. On the contrary, it appears to be the product of good lawyering. Drew better hire herself a good criminal defense attorney.
You are wrong. In civil court they would ask for money and have to show financial harm. In criminal they just need to show that by violating rules "users" agreed to the user caused harm to another person. I think the key issue here is age. If the user was of legal age (18 or older) then they should be nailed to the wall because they acted with careless malice.
jmho
I think you are correct. It is not reasonable to assume that students will do homework in isolation.
Now with that said, and as an individual who has taught college level science classes, the PRIMARY AIM of homework is to tunnel the student in on principles that need to be looked at in depth. Furthermore in science it is VITAL that students communicate with and teach each other. The proof lies in the fact, that that even this Profs, only allowed for it to represent 10% of the work. The exam is the time when the knowledge of the individual is tested.
I believe that this prof is way off base and really should think more about HOW HE TEACHES and tests his students.
Classes I have taught include general chemistry, developmental biology, cell biology, and pathology.
Hydrazine is not all that stable in aerobic conditions. In polluted air the life time will unlikely exceed 1 h. If it hits the ground and was unfortunate to not have the container with hydrazine rupture during reentry, then assuming the soils has trace metals, hydrazine shuld rapidly decompose. Dumping organic loam shuld afford you all the protection you shoul need
yes and the kicker of the whole thing and the reason I think this record company is daft, is that the sond quality was really really bad.
What exactly was being pirated? LOL
They did not prove these are stem cells, they just said they were.
As for killing the seed, that is not a good way to think about cancer. Cancer can arise from a stem cell or from a differentiated cell. For example, there is little doubt that hepatocellular carcinoma arises from hepatocytes, a differentiated cell. On the other hand. some leukemias are believed to arrise from progenitor cells in the blood. Now are the progenitor cells stem cells?? That is a raging debate.
Now in regards to needing cancer cells to study, well cancer cells are a moving target. While they arise from single cells, progressive generations are different. This is termed clonal expansion.
So agroup of scientists have inserted some genes into a primary cell and created a cancer cell line?????
The just reproved that cancer requires inititation AND promotion.
Lame
INteresting comments. Your intuition is better than you think.
The adult liver cell is considered to be the stem cell compartment for the adult liver. Grompee created this mouse strain to show that a hemopoetic stem cell also exists. He did serial hepatocyte transplants of "normal" littermates and used a purified hemopeotic cell line to show the compartment existed. Regeneration of the liver is one of the functions of the liver. Think about it....Evolution has selected the liver that is most capable of regenrating after cell death due to ingestion of some alkloid. The adult liver can have 2/3 of it killed and in less than 2 weeks the liver will have regenerated.
Specifically what was done: The strain of mouse Grompee uses has a defect in tyrosine metabolism, Without drug, the tyrosine kills the host liver cells. Give drug and that pathway is shunted and cells do not die. Grompee then takes the mouse off drug AND injects human hepatocytes into the portal vein (direct path to liver) where the human hepatoctes repopulate the liver. The crug on off cycle can be repeated up to 4 times (so says the press release.
While the human hepatocytes repopulate the mouse liver they are also still mouse hepatocytes around (I believe) the number of 20 x106 cells is way to low to be a whole liver.
As for novelty, I will give this a 6-7 on a scale of 10. Liver cells have been transplanted into mice before.
first this is an existing drug. You should have read the article more carefully. It is used to treat lactic acidosis so all that needs to be done is efficacy studies. While expensive, it is not as expensive as one would think becuase the Hoispitals tht DEVELOP ORPHAN drugs already exist and it is clear that this will be used as an adjuvant treatment, not a first line. The cost of the studies will be more in the area of 20-40 million at most and will piggy back on existing studies
First of all if their is no IP then that will not stop development. Actually, if these scientist would COLLABORATE, they would quickly find that institutions such as Pittsburgh, Harvard, UCLA and MANY OTHERS developing drugs that have fallen off patent or have no IP. Also, the NIH has a large division to do this as well. If the preclinical data is appealling, money WILL come
NOTE TO ALL: THe lion share of all new drugs coming out today are old drugs that are no longer patented and used on off targets. In other words they are the "side reactions" that were ignored the first time around I am currently involved in studies to bring a many decdes old drug out of the closet to be used for liver preservation during transplant.
Lastly as a greek, this scientist is an embarasment. Greeks are usually more clever.
Well the Terrorist wanted American society to change. Looks like their best foot soldiers are the AG and W's administration. The governments ability to decide what "activity" needs to be kept secret is violating every tennet of a democratic society. Even Ceasar was loved when he dissolved the senate, but then came Nero et al.
THis is beta revisisted.
SONY is so screwed. For the LESS THAN THE price of a PS3, one can buy a 360 and a Wii. And I assume as fact that MS will drop the price of the 360 by 50 bucks when the PS3 is released just to screw with Sony as sony did to MS when XBox released.
Beta picture quality WAS/IS FAR SUPERIOR TO the VHS format but its cost made it a nothing, a nothing at all.
While I have the money to buy a PS3, I have decided not to. There is little value that Sony adds except Blu-Ray that reminds me an aweful lot of BetaMax of yore.
IT IS TOO EXPENSIVE FOR MASS ADOPTION. I will wait til they release the PS3 and within a month, I bet MS will drop the price of the XBox, and I will buy one. In the meantime, Wii, is in the cards. Cool looking games
It has to do with hte old axiom that it is OK to laugh with someone but it is wrong to laugh AT someone.
He goes onto a site and begins with a bait picture (which is a lie) to entice someone into a private conversation and then publishes the response. Anyone who thinks this is good natured humor knows little of human nature. This activity is particularly nasty because it often entices the dark side of owns nature to come out and then lays shame on them so this fucking worthless blogger can have something to write about. He was not conducting and experiment to prove any hypothesis, he was just looking for something to write about because his mind is very uncreative. Candid CAMERA THAT WAS FUNNY BECAUSE IN THE END THE PARTICIPANTS WERE LAUGHING TO. HERE THAT IS NOT THE CASE
you keep saying that but u do not explain why? Glider is a completely useless program without the code of WoW. In other words the only thing it does is mine the data generated by the client program WoW. The strech is not to far for me to see that they are infringing on WoW copyrighted code. Please explain to me how they/glider are not?
Since you do not play you would not understand....but alas your comments imply you have played. Leveling is part of the game. By your logic what is the point of rolling dice in Monopoly? Mabe we should just get a random number generator and let it play till all property is bought. In WoW Leveling is part of the game and while instances are also part of the game so are BGs. The bot allows for PvP players to develop far faster than rules allow. to the players that do there own levling the is a pratical screw in the ass. Also the bots will change distribution of resources so that it may take non cheaters longer. AND THAT IS NOT FAIR
I guess the regular user who is not cheating is just shit out of luck.
I really doubt that and you are being a bit over the top. The legal arguement would never stand if the hackers were modifing freeware. But this is a paid service where the code is subverting the pleasure of customers who pay to use the online community. The hackware is specifically designed to subvert the rules of play. Do u deny that? As for the free world, I am WAY more worried about Homeland security than of the legal actions of Blizzard to protect its online community from cheaters.
agent for whom??? I am just a game player who does not cheat and wishes to play with others that do not cheat. I will take from your snide comment that you see nothing wrong with coders writing code that will subvert MY PLEASURE that I paid good money for. You would make a good manager at Walmart Mr Mann
you are now rationalizing why it is okay to cheat. BTW, your argument stinks the kid at home DID THE MINING himself , the bot user did not. How difficult the task is does not matter and is known as a "red Herring"
So do you think it is OK to cheat? Do You like to play with other players That are cheating? I do not pay ~15 bucks a month to have to pay a computer game I cheat at? I have played PS2, PS3, Wii and a few others and I have NEVER used a cheat code. I consider them repulsive. also why whould I spend money on a game I cheat at? I could just as well save my money and get a deck of cards and just cheat at solitaire. I do not fault Blizzrd for attempting to do what they are doing I just wish they did not have to. And Yes what they/blizzard is doing is an impossible task imho
OOPS! we were hacked! our source code was stolen!
OMG!! It's all over pirate bay! sorry!
In other words, legally say "Blizzard.... Go To Hell."
Well are you not a swell guy or what??? So what do you say to the guy that is NOT cheating? "Hey that is your problem, you oughta cheat too" This code sucks and people that develop it suck as well. They are people that do not believe rules are for them. Why don't they just go write ther own Open source versions of WoW and play with themselves. I want to play the game WITHOUT having to resort to cheat.
As revealed by the indictment, the "unauthorized access" results from various violations of MySpace's terms of service. I'm no expert on the Computer Fraud and Abuse Act (CFAA), but at least one court has found that violation of a company's terms of service constitutes "unauthorized access" for purposes of the Act. See America Online, Inc. v. LCGM, Inc., 46 F. Supp. 2d 444, 450-51 (E.D. Va. 1998). The CFAA makes it illegal to, among other things, "intentionally access[] a computer without authorization or exceed[] authorized access, and thereby obtain[] . . . information from any protected computer if the conduct involved an interstate or foreign communication." 18 U.S.C. 1030(a)(2)(C). The punishment for violating this subsection of the CFAA is a fine or up to 5 years imprisonment if "the offense was committed in furtherance of any criminal or tortious act in violation of the Constitution or laws of the United States or of any State." Id. (c)(2)(B)(ii). (Otherwise there needs to be some sort of pecuniary gain or the information gained needs to be worth $5,000 or more.) So, how did Drew allegedly violate the CFAA? MySpace's terms of service forbid you from lying to MySpace or using your account to harrass other users, obtain personal information from minors, posting photos of people without their consent, etc. Drew broke all of these terms when, among other things, she registered as a teenage boy, got personal information from the 13 year old victim, and posted a picture of a teenage boy without his consent. Because she violated MySpace's terms of service, her access to MySpace's servers was "unauthorized access." Her unauthorized access involved an "interstate . . . communication" because MySpace's servers are in California and Drew accessed them from a computer in Missouri. Drew allegedly used her account and the information she received to harass the victim to the point where it constituted the tort of intentional infliction of emotional distress, a well-recognized tort in Missouri (and, to my knowledge, recognized in all states). See, e.g., Central Missouri Elec. Co-op. v. Balke, 119 S.W.3d 627, 636 (Mo. Ct. App. 2003) ("To recover for intentional infliction of emotional distress, the [plaintiff] must show (1) the defendant's conduct was extreme and outrageous; (2) the defendant acted intentionally or recklessly; and (3) the defendant's conduct caused extreme emotional distress resulting in bodily harm."). Thus, her unauthorized access "was committed in furtherance of any . . . tortious act in violation of the . . . laws of the . . . any State." Now, you could argue that the indictment may be an abuse of prosecutorial discretion, but I don't see how you can argue that this indictment is frivolous. On the contrary, it appears to be the product of good lawyering. Drew better hire herself a good criminal defense attorney.
You are wrong. In civil court they would ask for money and have to show financial harm. In criminal they just need to show that by violating rules "users" agreed to the user caused harm to another person. I think the key issue here is age. If the user was of legal age (18 or older) then they should be nailed to the wall because they acted with careless malice. jmho
I think you are correct. It is not reasonable to assume that students will do homework in isolation. Now with that said, and as an individual who has taught college level science classes, the PRIMARY AIM of homework is to tunnel the student in on principles that need to be looked at in depth. Furthermore in science it is VITAL that students communicate with and teach each other. The proof lies in the fact, that that even this Profs, only allowed for it to represent 10% of the work. The exam is the time when the knowledge of the individual is tested. I believe that this prof is way off base and really should think more about HOW HE TEACHES and tests his students. Classes I have taught include general chemistry, developmental biology, cell biology, and pathology.
Hydrazine is not all that stable in aerobic conditions. In polluted air the life time will unlikely exceed 1 h. If it hits the ground and was unfortunate to not have the container with hydrazine rupture during reentry, then assuming the soils has trace metals, hydrazine shuld rapidly decompose. Dumping organic loam shuld afford you all the protection you shoul need
except that Apple sent pictures of just such a device to the patent office over 4 months prior to the initial submission. LOL
yes and the kicker of the whole thing and the reason I think this record company is daft, is that the sond quality was really really bad. What exactly was being pirated? LOL
They did not prove these are stem cells, they just said they were. As for killing the seed, that is not a good way to think about cancer. Cancer can arise from a stem cell or from a differentiated cell. For example, there is little doubt that hepatocellular carcinoma arises from hepatocytes, a differentiated cell. On the other hand. some leukemias are believed to arrise from progenitor cells in the blood. Now are the progenitor cells stem cells?? That is a raging debate. Now in regards to needing cancer cells to study, well cancer cells are a moving target. While they arise from single cells, progressive generations are different. This is termed clonal expansion.
So agroup of scientists have inserted some genes into a primary cell and created a cancer cell line????? The just reproved that cancer requires inititation AND promotion. Lame
INteresting comments. Your intuition is better than you think. The adult liver cell is considered to be the stem cell compartment for the adult liver. Grompee created this mouse strain to show that a hemopoetic stem cell also exists. He did serial hepatocyte transplants of "normal" littermates and used a purified hemopeotic cell line to show the compartment existed. Regeneration of the liver is one of the functions of the liver. Think about it....Evolution has selected the liver that is most capable of regenrating after cell death due to ingestion of some alkloid. The adult liver can have 2/3 of it killed and in less than 2 weeks the liver will have regenerated.
Specifically what was done: The strain of mouse Grompee uses has a defect in tyrosine metabolism, Without drug, the tyrosine kills the host liver cells. Give drug and that pathway is shunted and cells do not die. Grompee then takes the mouse off drug AND injects human hepatocytes into the portal vein (direct path to liver) where the human hepatoctes repopulate the liver. The crug on off cycle can be repeated up to 4 times (so says the press release.
While the human hepatocytes repopulate the mouse liver they are also still mouse hepatocytes around (I believe) the number of 20 x106 cells is way to low to be a whole liver.
As for novelty, I will give this a 6-7 on a scale of 10. Liver cells have been transplanted into mice before.
first this is an existing drug. You should have read the article more carefully. It is used to treat lactic acidosis so all that needs to be done is efficacy studies. While expensive, it is not as expensive as one would think becuase the Hoispitals tht DEVELOP ORPHAN drugs already exist and it is clear that this will be used as an adjuvant treatment, not a first line. The cost of the studies will be more in the area of 20-40 million at most and will piggy back on existing studies
First of all if their is no IP then that will not stop development. Actually, if these scientist would COLLABORATE, they would quickly find that institutions such as Pittsburgh, Harvard, UCLA and MANY OTHERS developing drugs that have fallen off patent or have no IP. Also, the NIH has a large division to do this as well. If the preclinical data is appealling, money WILL come
NOTE TO ALL: THe lion share of all new drugs coming out today are old drugs that are no longer patented and used on off targets. In other words they are the "side reactions" that were ignored the first time around I am currently involved in studies to bring a many decdes old drug out of the closet to be used for liver preservation during transplant.
Lastly as a greek, this scientist is an embarasment. Greeks are usually more clever.
Well the Terrorist wanted American society to change. Looks like their best foot soldiers are the AG and W's administration. The governments ability to decide what "activity" needs to be kept secret is violating every tennet of a democratic society. Even Ceasar was loved when he dissolved the senate, but then came Nero et al.
THis is beta revisisted. SONY is so screwed. For the LESS THAN THE price of a PS3, one can buy a 360 and a Wii. And I assume as fact that MS will drop the price of the 360 by 50 bucks when the PS3 is released just to screw with Sony as sony did to MS when XBox released. Beta picture quality WAS/IS FAR SUPERIOR TO the VHS format but its cost made it a nothing, a nothing at all.
While I have the money to buy a PS3, I have decided not to. There is little value that Sony adds except Blu-Ray that reminds me an aweful lot of BetaMax of yore. IT IS TOO EXPENSIVE FOR MASS ADOPTION. I will wait til they release the PS3 and within a month, I bet MS will drop the price of the XBox, and I will buy one. In the meantime, Wii, is in the cards. Cool looking games