"A scientific colleague tells me about a recent trip to the New Guinea highlands, where she visited a stone age culture hardly contacted by Western civilization. They were ignorant of wristwatches, soft drinks, and frozen food. But they knew about Apollo 11. They knew that humans had walked on the Moon. They knew the names of Armstrong and Aldrin and Collins." from A Pale Blue Dot by Carl Sagan
Probability is not directly proportional to dose. With dose response curves (increasing the concentrations of a chemical), the old dogma is that you can treat with a really high dose where it is easy to see a response (e.g., tumor formation), and then you can extrapolate using those high dose points and make basically a straight line to determine what low dose is "safe". Somewhat recent work has brought to light a concept known as hormesis, which essentially means that low doses can actually have opposite effects than high doses (e.g., an anti-cancer drug that kills cells at high doses can actually increase growth rates at low doses). It is speculated that this might occur due to moderate stimulation of biological stress responses, which can be beneficial. I'd note that scientists have seen hormesis for a while, but it was shied away from to some degree because of the taint caused by the pseudoscience of homeopathy. While hormesis does not necessarily apply to every chemical and response measured, it at least challenges the commonly accepted notion that what you do with the 1000 times concentrated dose is extrapolatable to the low dose.
Just FYI about generics and lipitor (atorvastatin). Lipitor falls in a class of molecules called statins, all of which inhibit the exact same enzyme (HMGCoA reductase, the rate limiting step in cholesterol biosynthesis). Although they all are somewhat distinct due to being different molecules: they may have different absorption, excretion, off target effects (side effects), efficiency at inhibiting the desired enzyme, etc. But the point is, there already exist generic statins...
Statins can inhibit many other cellular processes besides cholesterol synthesis such as coenzyme Q10 synthesis (involved in ATP energy production, pretty important, so it's no wonder there are side-effects). Hopefully the loss of patent will cause drug companies to find new drugs with less side effects (like the dual inhibitors discussed in basic research here http://www.ncbi.nlm.nih.gov/pubmed/21903868, though that the molecules discussed don't seem realistic, but the approach is reasonable).
For me and many people I know, the issue is privacy. Rather than Facebook selling your information to other companies, Google(+) sells ads catered to your online habits without compromising your privacy.
The important part will be if he formulates a new theory or extends Einstein's theory such that we could make more or more accurate predictions about the universe. His math skills are not the only prerequisite here. Einstein himself said "Imagination is more important than knowledge"
"Professor John Ross, who vows to help find some grant funding to support Jake and his work " This we have to watch out for. Science funding can be difficult to get, especially in tough economic times, and hopefully this child isn't simply exploited to bring in money (or fame) for John Ross. Hopefully Robin Williams will help this kid out if necessary.
Anyone who makes large blanket statements about the their polar opposing group, is not helping. The particular issue at hand is not really relevant: Democrat, Republican; Christian, Muslim; Mac, PC; iphone, android; etc. I think it may all stem from the same underlying issue - millions of years of evolution as a dominance hierarchy-based tribal species. A part of our primate brain evolved for tribal loyalty and for following leaders. Part of the solution is to first recognize the problem. In addition, remember that power corrupts and you are probably naive if you think your favorite political group/politician or yourself is immune. People should be judged for their individual merits, not by the classification under which they are labeled. This is just a way to "turn off" the brain in order to simply decisions, by choosing loyalty to ones tribe (e.g., political group).
I'm relatively ignorant, but AFAIK, it is common for "random number generators" with computers to not really be random at least via software because there will be underlying code based on an algorithm, since they are logical devices. So if you figure out the algorithm you can predict the "randomness". However, I think you can add some kind of specialized hardware device that does something truly random like measure radioactive decay from a radioactive element or roll some physical dice or something, and then it would be truly random... Someone please correct me if I'm mistaken.
I can foresee a day when the desktop computer isn't necessary, and in it's place is instead a dock for your smartphone. Plug in the smartphone into the dock and then use a standard keyboard, mouse, monitor, and speakers. I could type a paper that way for sure.
Opt out is BS, you should have to opt in... I wasn't interested in being a part of this but b/c I don't care about it, I'm apart of it. You should only be included if you care enough to take some sort of action.
It's a nice idea to think that conservatives and liberals are flip sides of the coin, and we need both. Yadda yadda. But it just doesn't work out that way. Liberals are on the wrong side of history. Consider Russia for instance. There are conservatives there, and there are liberals there. Do they really need those liberals sending them in the wrong direction again? What good does it do them? From our modern perspective we can see just how wrong-headed they are. But left and right over there is the same thing as left and right over here, just centered around a different origin. There's no reason to believe our liberals are any better than theirs, and in the future we'll look back and see just how wrong-headed they are today. The people calling for the removal of personal responsibility today are no different from the commies.
Now of course conservatives aren't perfect. Everyone makes mistakes. But at least conservatives believe in the constitution, instead of glorifying the same old mistakes. At least conservatives look to a future where everyone is better off, instead of liberals who simply try to manipulate the power structure so that is favorable to them alone.
Disclaimer: I don't believe what I wrote, but it's using the same 'my side is always right' mentality that you used.
I'd note how nice BFG was. Their customer service was great in my experience. They did not require a receipt. Lifetime meant life of the company. They were clearly trying to honor older lifetime warranties, because they had a deal where you could give them your old AGP card and for a low sum of money, they would give you a much newer model PCIx card.
I'd guess it's not cheap to start an airline, and with lots of existing competition, I'd guess that makes it more difficult, although by no means impossible. Free market you say? Since the government has (and probably will again) just bail out the existing airlines, even though they have failing business models, that removes the possibility that the established carriers can go under, which prevents the opening up of demand ($) that a new company could try to fill. Less available revenue combined with greater competition decreases the likelihood that a new carrier enters the market. Oh, and lets not forget the TSA makes air travel horrifically painful no matter what airline you fly, thus (IMO) causing even an awesome airline to still have a awful overall travel experience.
And then the face of the kid who gets somebody else's calculator where the equals button doesn't work. And maybe the face of the kid who is tech savy and figures out he got the cheaters hacked calculator, as he may ethically ponder - cheat myself and get a better grade, or turn in one cheater who without their cheating instrument will probably be toward the bottom, but if they are turned in they may be removed from the curve all together.
Wow for $100 million dollars you think they could design a freaking menu interface. The beta was absolutely terrible, not intuitive at all and you end up with like 3 chat windows for talking with one person. I hope it was 100% remade before launch with some of that 100 million. The gameplay is ok, it feels like Starcraft but with better graphics. So if you are feeling nostalgic, you can drop $60 or just buy an old used copy for probably $5. I'll probably still buy it just to play occasionally online with friends though...
Slashdot Mirror
Whats the difference between those?
"A scientific colleague tells me about a recent trip to the New Guinea highlands, where she visited a stone age culture hardly contacted by Western civilization. They were ignorant of wristwatches, soft drinks, and frozen food. But they knew about Apollo 11. They knew that humans had walked on the Moon. They knew the names of Armstrong and Aldrin and Collins." from A Pale Blue Dot by Carl Sagan
Probability is not directly proportional to dose. With dose response curves (increasing the concentrations of a chemical), the old dogma is that you can treat with a really high dose where it is easy to see a response (e.g., tumor formation), and then you can extrapolate using those high dose points and make basically a straight line to determine what low dose is "safe". Somewhat recent work has brought to light a concept known as hormesis, which essentially means that low doses can actually have opposite effects than high doses (e.g., an anti-cancer drug that kills cells at high doses can actually increase growth rates at low doses). It is speculated that this might occur due to moderate stimulation of biological stress responses, which can be beneficial. I'd note that scientists have seen hormesis for a while, but it was shied away from to some degree because of the taint caused by the pseudoscience of homeopathy. While hormesis does not necessarily apply to every chemical and response measured, it at least challenges the commonly accepted notion that what you do with the 1000 times concentrated dose is extrapolatable to the low dose.
Just FYI about generics and lipitor (atorvastatin). Lipitor falls in a class of molecules called statins, all of which inhibit the exact same enzyme (HMGCoA reductase, the rate limiting step in cholesterol biosynthesis). Although they all are somewhat distinct due to being different molecules: they may have different absorption, excretion, off target effects (side effects), efficiency at inhibiting the desired enzyme, etc. But the point is, there already exist generic statins...
Statins can inhibit many other cellular processes besides cholesterol synthesis such as coenzyme Q10 synthesis (involved in ATP energy production, pretty important, so it's no wonder there are side-effects). Hopefully the loss of patent will cause drug companies to find new drugs with less side effects (like the dual inhibitors discussed in basic research here http://www.ncbi.nlm.nih.gov/pubmed/21903868, though that the molecules discussed don't seem realistic, but the approach is reasonable).
Windmills do not work that way! Goodnight
For me and many people I know, the issue is privacy. Rather than Facebook selling your information to other companies, Google(+) sells ads catered to your online habits without compromising your privacy.
and obligatory http://xkcd.com/918/
The important part will be if he formulates a new theory or extends Einstein's theory such that we could make more or more accurate predictions about the universe. His math skills are not the only prerequisite here. Einstein himself said "Imagination is more important than knowledge"
"Professor John Ross, who vows to help find some grant funding to support Jake and his work " This we have to watch out for. Science funding can be difficult to get, especially in tough economic times, and hopefully this child isn't simply exploited to bring in money (or fame) for John Ross. Hopefully Robin Williams will help this kid out if necessary.
Anyone who makes large blanket statements about the their polar opposing group, is not helping. The particular issue at hand is not really relevant: Democrat, Republican; Christian, Muslim; Mac, PC; iphone, android; etc. I think it may all stem from the same underlying issue - millions of years of evolution as a dominance hierarchy-based tribal species. A part of our primate brain evolved for tribal loyalty and for following leaders. Part of the solution is to first recognize the problem. In addition, remember that power corrupts and you are probably naive if you think your favorite political group/politician or yourself is immune. People should be judged for their individual merits, not by the classification under which they are labeled. This is just a way to "turn off" the brain in order to simply decisions, by choosing loyalty to ones tribe (e.g., political group).
I'm relatively ignorant, but AFAIK, it is common for "random number generators" with computers to not really be random at least via software because there will be underlying code based on an algorithm, since they are logical devices. So if you figure out the algorithm you can predict the "randomness". However, I think you can add some kind of specialized hardware device that does something truly random like measure radioactive decay from a radioactive element or roll some physical dice or something, and then it would be truly random... Someone please correct me if I'm mistaken.
I can foresee a day when the desktop computer isn't necessary, and in it's place is instead a dock for your smartphone. Plug in the smartphone into the dock and then use a standard keyboard, mouse, monitor, and speakers. I could type a paper that way for sure.
(Morbo yelling) Preservatives do not work that way! Goodnight
Opt out is BS, you should have to opt in... I wasn't interested in being a part of this but b/c I don't care about it, I'm apart of it. You should only be included if you care enough to take some sort of action.
It's a nice idea to think that conservatives and liberals are flip sides of the coin, and we need both. Yadda yadda. But it just doesn't work out that way. Liberals are on the wrong side of history. Consider Russia for instance. There are conservatives there, and there are liberals there. Do they really need those liberals sending them in the wrong direction again? What good does it do them? From our modern perspective we can see just how wrong-headed they are. But left and right over there is the same thing as left and right over here, just centered around a different origin. There's no reason to believe our liberals are any better than theirs, and in the future we'll look back and see just how wrong-headed they are today. The people calling for the removal of personal responsibility today are no different from the commies.
Now of course conservatives aren't perfect. Everyone makes mistakes. But at least conservatives believe in the constitution, instead of glorifying the same old mistakes. At least conservatives look to a future where everyone is better off, instead of liberals who simply try to manipulate the power structure so that is favorable to them alone.
Disclaimer: I don't believe what I wrote, but it's using the same 'my side is always right' mentality that you used.
It's probably just a gene that when mutated is embryonic lethal. (bad joke)
"Technology is never good or evil. It's how it's used... like the death ray." -Farnsworth
I'd note how nice BFG was. Their customer service was great in my experience. They did not require a receipt. Lifetime meant life of the company. They were clearly trying to honor older lifetime warranties, because they had a deal where you could give them your old AGP card and for a low sum of money, they would give you a much newer model PCIx card.
That's true. I saw it in this documentary
I'd guess it's not cheap to start an airline, and with lots of existing competition, I'd guess that makes it more difficult, although by no means impossible. Free market you say? Since the government has (and probably will again) just bail out the existing airlines, even though they have failing business models, that removes the possibility that the established carriers can go under, which prevents the opening up of demand ($) that a new company could try to fill. Less available revenue combined with greater competition decreases the likelihood that a new carrier enters the market. Oh, and lets not forget the TSA makes air travel horrifically painful no matter what airline you fly, thus (IMO) causing even an awesome airline to still have a awful overall travel experience.
And then the face of the kid who gets somebody else's calculator where the equals button doesn't work. And maybe the face of the kid who is tech savy and figures out he got the cheaters hacked calculator, as he may ethically ponder - cheat myself and get a better grade, or turn in one cheater who without their cheating instrument will probably be toward the bottom, but if they are turned in they may be removed from the curve all together.
Wow for $100 million dollars you think they could design a freaking menu interface. The beta was absolutely terrible, not intuitive at all and you end up with like 3 chat windows for talking with one person. I hope it was 100% remade before launch with some of that 100 million. The gameplay is ok, it feels like Starcraft but with better graphics. So if you are feeling nostalgic, you can drop $60 or just buy an old used copy for probably $5. I'll probably still buy it just to play occasionally online with friends though...
Indeed. Some studies suggest that what is called Emotional intelligence (or sometimes 'EQ') is a better predictor of success in life.
I can't wait for a mobile browser (running in android) that uses addons... specifically adblock.
money != productivity"
Yeah. It looks and reads like a science fair project...
Pseudoscience is the word you are looking for. Sadly though since it has the suffix science in it, some people might see that word as a credential...