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Mixing brain cells and nanodots

Roland Piquepaille writes "It's not the first time that animal brain cells have been used in conjunction with nanoparticles. But now, a team of Israeli researchers have grown self-organizing networks of rat brain cells by binding them to carbon nanotubes. In a short article, New Scientist reports that these neural networks are remarkably stable, surviving for almost three months in the lab. These hybrid networks could be used in future biological sensors. For example, they could identify a poison by measuring its effect on such a network of brain cells."

55 of 73 comments (clear)

  1. Wait, what's this about nanodots? by Zarel · · Score: 5, Interesting

    I see the summary and article mention nanotubes but no nanodots, and I've never heard of nanodots before. Wikipedia doesn't have an article about them. What are they?

    --
    Want a high quality FOSS RTS game? Try Warzone 2100!
    1. Re:Wait, what's this about nanodots? by Tx · · Score: 4, Funny

      They're a little like a slashdot, only smaller.

      --
      Oh no... it's the future.
    2. Re:Wait, what's this about nanodots? by Anonymous Coward · · Score: 5, Informative

      Nanodot? It's a catchall term for one of those nano-sized spherical looking things.

      A buckyball is a kind of nanodot. Some micelles could be considered nanodots.

      HTH...

  2. Heh by MobileTatsu-NJG · · Score: 4, Funny

    "For example, they could identify a poison by measuring its effect on such a network of brain cells"

    proc DetectPoison ()
    {
          global $NeuralActivity;
          if($NeuralActivity == 0) return true;
          return false;
    }

    --

    "I like to lick butts!" by MobileTatsu-NJG (#32700246) (Score:5, Informative)

    1. Re:Heh by Mayhem178 · · Score: 2, Informative

      Wow...that is just awful and not right! You are a bad, bad person! How do you sleep at night?

      proc DetectPoison()
      {
      global $NeuralActivity;
      return $NeuralActivity == 0;
      }

      There, that's better. :D

      --

      "You will pay for your lack of vision..." - Emperor Palpatine to Ray Charles

    2. Re:Heh by cyberbian · · Score: 1

      Wouldn't that be:


      proc DetectPoison(NeuralActivity)
      {
      if(NeuralActivity==0) return true;
      return false;
      }

      I suppose that NeuralActivity would preexist in the softs? ;)
      --
      if I claimed I was emperor just because some watery tart lobbed a scimitar at me they'd put me away!
    3. Re:Heh by mikesd81 · · Score: 1

      Okay, all kidding aside. They probaly wouldn't be re-useable, right? How many would a person have to carry then to actually search a building area by area or floor by floor, you get the point. How cost-efficent, or efficient even, would that be?

      --
      That which does not kill me only postpones the inevitable.
    4. Re:Heh by Joebert · · Score: 1

      You're both insane...

      --
      Wanna fight ? Bend over, stick your head up your ass, and fight for air.
    5. Re:Heh by chris_eineke · · Score: 1

      (defun detect-poison (neural-activity)
          (= neural-activity 0))

      --
      "All you have to do is be fragile and grateful. So stay the underdog." Chuck Palahniuk, Choke
    6. Re:Heh by Retric · · Score: 1

      Or

      proc DetectPoison(NeuralActivity)
      {
        return (NeuralActivity==0);
      }

    7. Re:Heh by Mayhem178 · · Score: 1, Informative

      You scheming bastard... :P

      --

      "You will pay for your lack of vision..." - Emperor Palpatine to Ray Charles

    8. Re:Heh by powers_722 · · Score: 1

      You meant...

      proc DetectPoison ()
      {
                  global $NeuralActivity;
                  return ($NeuralActivity == 0);
      }

      Right?

    9. Re:Heh by MobileTatsu-NJG · · Score: 1

      Hmm.. that explains why my Mel scripts don't work.

      --

      "I like to lick butts!" by MobileTatsu-NJG (#32700246) (Score:5, Informative)

  3. Real programmers use C by mangu · · Score: 1


    int DetectPoison()
    {
        extern int NeuralActivity;
        return !NeuralActivity;
    }

    Simpler code.
    Runs faster.

  4. The next logical step by Valacosa · · Score: 3, Funny

    The next logical step: implant the carbon nanotubes into a rat embryo and let it develop into an adult rat. Think of the applications! We could know what rats are thinking at all times!

    "Mmmm...cheese."

    Then it's just a quick leap to remote controlled rats. That would be fun.

    --
    "Live as if you'll die tomorrow." Ridiculous. You could die later today.
    1. Re:The next logical step by cp.tar · · Score: 1

      Yes, fun.

      Cranium rats. Just what we need.

      If there are four or more in one place, they can cast spells, y'know?

      --
      Ignore this signature. By order.
    2. Re:The next logical step by alshithead · · Score: 1

      Ahhhh!!! We are Borg...

      --
      I reserve the right to think for myself. Others' opinions are optional. Puppy on lap = typos...not illiteracy.
    3. Re:The next logical step by ichigo+2.0 · · Score: 1

      But their tails are so tasty! If they get out of control, we just need to create an army of undead zombies, what could go wrong?

    4. Re:The next logical step by cp.tar · · Score: 1

      Their tails are worth 1 gp apiece.

      We can set bounties on them.

      At least until Ankh-Morporkians hear of it, invade Planescape and start farming the rats for their tails.

      My brain hurts.

      --
      Ignore this signature. By order.
    5. Re:The next logical step by bondjamesbond · · Score: 1

      Not thinking, you insensitive clod, PONDERING.

      The Brain: Are you pondering what I'm pondering??

    6. Re:The next logical step by WilliamSChips · · Score: 1

      I think so Brain, but hasn't Freenode been hacked?

      --
      Please, for the good of Humanity, vote Obama.
    7. Re:The next logical step by pookemon · · Score: 1

      No - first you need the nano cheese, then you can grow the rats...

      --
      dnuof eruc rof aixelsid
  5. They've already got remote controlled rats... by Anonymous Coward · · Score: 2, Interesting

    http://news.nationalgeographic.com/news/2002/05/05 01_020501_roborats.html

    Couple this with:

    http://www.washingtonpost.com/ac2/wp-dyn/A17434-20 03Oct12?language=printer

    and you get monkeys that can control rats with their mind!

    I for one welcome our new monkey overlords and their army of mind controlled rats...

  6. Microdots by Joebert · · Score: 3, Funny
    In a short article, New Scientist reports that these neural networks are remarkably stable, surviving for almost three months in the lab.

    Awesome ! The last batch of Microdots I got only lasted about 7 hours.
    --
    Wanna fight ? Bend over, stick your head up your ass, and fight for air.
  7. They're Pinky and The Brain by Anonymous Coward · · Score: 3, Funny

    Yes, Pinky and The Brain
    One is a genius
    The other's insane.
    They're laboratory mice
    Their genes have been spliced
    They're dinky
    They're Pinky and The Brain, Brain, Brain, Brain
    Brain, Brain, Brain, Brain
    Brain.

    Before each night is done
    Their plan will be unfurled
    By the dawning of the sun
    They'll take over the world.

    1. Re:They're Pinky and The Brain by painQuin · · Score: 1

      Narf.

      --
      A guilty conscience means at least you've got one.
  8. Re:Ethics by uncoveror · · Score: 1

    This is a slippery slope.

    --
    The Uncoveror: It's the real news.
  9. Re:Ethics by TheDreadSlashdotterD · · Score: 2, Insightful

    Ethics? Who needs ethics?

    I know the above link is OT and disturbing (even by my standards), but if the parts of an animal or a human can benefit the rest of the world, then why not use them? It's like nature (or God, if you prefer) handing us a cherished gift and throwing it in the dumpster because we think it disgraces us morally/ethically. What a load of crap. It's just a blob of molecules arranged in a certain way. Get over it.

    --
    I have nothing to say.
  10. Re:Somewhat related by groundround · · Score: 1

    Great news about you daughter, but what's wrong with healing adults?

  11. Hardware Vs Biological Routes by sc0p3 · · Score: 3, Interesting

    This is interesting development in light of the advances of the hardware methods for neural networks. There seems to be two routes to mimic AI / biology; Hardware simulation of neurons, and biological embedding of neurons on chips.

    The article says its to "identify a compound" which is achieved by embedding the olfactory/taste/heat etc neurons on chips and monitoring the signals generated. These neurons have special proteins in their membranes to identify the compounds, but this could very easily be extended to AI networks, and opens up alot more possibility.

    Robotic control algorithms brached in the 50's-60's into serial control and neurological control. The processing limitations in earlier days inhibited the latter development path, but there have been a number of interesting developments like this one recently showing progression of the neural paths - eg Sony Robodog a few days earlier.

  12. You are mistaken... by hachete · · Score: 1
    --
    Patriotism is a virtue of the vicious
  13. But how does this relate to detecting poison? by manx801 · · Score: 1

    Call me a skeptic, but I fail to see the correlation between coaxing neurons to connect up in an organized way and building a sensor that is of practical for solving a particular problem. Most neuroscientists would probably agree that the apparent intelligence, or problem solving capability of columns in cortex is due to the interplay between groups of neurons that have been connected up in a very special way through, for example, pairwise co-occurrence of stimuli.

    1. Re:But how does this relate to detecting poison? by Otter · · Score: 1

      Not that this work is anywhere near practical utility yet, but creating a network that responds to a specific stimulus with a specific action is much simpler than the kind of complex response you're talking about. Given the biological tools, it shouldn't be much harder than, say, designing an electronic smoke alarm.

  14. It's the BORG by Anonymous+Monkey · · Score: 1

    Think about it, Borg nano-bots. Be afraid.

    --
    We are the Borg...
  15. Re:Trippin by Canar · · Score: 1
    The 60's called. They want their sensor back.
    The 90's called. They want their joke back.
  16. Uploaded cats are a bad idea. by LionKimbro · · Score: 1
    "Cats," says Pamela. "He was hoping to trade their uploads to the Pentagon as a new smart bomb guidance system in lieu of income tax payments. Something about remapping enemy targets to look like mice or birds or something before feeding it to their sensorium. The old kitten and laser pointer trick."

    Manfred stares at her, hard. "That's not very nice. Uploaded cats are a bad idea."


    -- Accelerando
  17. Re:Trippin by cnettel · · Score: 1

    The 2200s called, they want their humpbacks back.

  18. Film at 11 by Frightening · · Score: 1

    American congress was poisoned 50 years ago, effects still strong..

  19. Re:Trippin by k4_pacific · · Score: 3, Funny

    2002 called, they want their The 90s called. they want their joke back joke back.

    --
    Unknown host pong.
  20. Mod parent down for blatant plagiarism! by FleaPlus · · Score: 4, Informative

    When reading the parent comment, I thought it was a little bit odd that it was talking about stem cells when the article has nothing to do with stem cells. After a quick google search, it turns out that the parent comment is actually a verbatim copy of a comment by someone else on a story last year:

    http://science.slashdot.org/comments.pl?sid=171904 &cid=14316980

    In fact, just about all the prior comments by "janet-on" seem to be verbatim copies of comments made by other people. The trick seems to work rather well, considering that the previous three comments all got modded to a score of 5, and the current comment is now at score 4.

    Personally, I'm guessing that "janet-on" is a bot someone made to try to accumulate karma, to allow them to moderate comments.

    1. Re:Mod parent down for blatant plagiarism! by ChrisGilliard · · Score: 1

      Personally, I'm guessing that "janet-on" is a bot someone made to try to accumulate karma

      Yeah, either that or a rat brain/nanodot combo made to try to accumulate karma.

      --
      No Sigs!
  21. Re:Ethics by MisaDaBinksX4evah · · Score: 1

    Brain cells are one of the places we know become feeling and even conscious beings. So... is it ethical for us to set them in products?

    I'm aware that we already do all kinds of unholy things to animals for research, but this seems different.


    It's true that playing with some cells in a dish is different than shoving tubes into an animal's organs and such. Which seems more ethical again?

    --
    Misa no botha with yousa.
  22. reacts to poison? by DogAlmity · · Score: 1

    Wouldn't it react by, dying? And couldn't you just use any living tissue for that?

  23. Re:Somewhat related by OctaviusIII · · Score: 1

    1. Not at all remotely connected to the topic
    2. Stop plagiarising
    3. Personal experience and a heartwarming tale do not make science or ethical norms, although they do make the reddest of herrings

    --
    What's this? Another weblog? On transit?
  24. May as well get it over with by stunt_penguin · · Score: 1

    1. I for one welcome our new beowlf cluster of rodent-neuron-based overlords 2. Compare to ghost in the Shell 3. ??? 4. Profit!

    --
    When the posters fear their moderators, there is tyranny; when the moderators fears the posters, there is liberty.
    1. Re:May as well get it over with by Velocir · · Score: 1

      But only in Soviet Russia...

  25. Re:Ethics by ScentCone · · Score: 1

    Brain cells are one of the places we know become feeling and even conscious beings. So... is it ethical for us to set them in products?

    Well, if you're not actually putting them in a framework that, by its very nature, can possibly develop into an actual brain... then, yes, certainly.

    --
    Don't disappoint your bird dog. Go to the range.
  26. Re:Ethics by Liam+Slider · · Score: 1
    Brain cells are one of the places we know become feeling and even conscious beings. So... is it ethical for us to set them in products?
    Brain cells no...not really. Complex brains made up of brain cells in the right configuration do.
  27. Re:Ethics by wtansill · · Score: 1
    Brain cells are one of the places we know become feeling and even conscious beings. So... is it ethical for us to set them in products?

    I'm aware that we already do all kinds of unholy things to animals for research, but this seems different.

    OK -- we'll use brain cells from polititcians. Better? Oh wait...
    --
    The contest for ages has been to rescue liberty from the grasp of executive power. -- Daniel Webster
  28. Re:Trippin by heinousjay · · Score: 1

    My mom called. She doesn't want anything back, but it was nice to hear from her.

    --
    Slashdot - where whining about luck is the new way to make the world you want.
  29. Celldeath is somtimes a bad mesure. by The+Creator · · Score: 1

    There are many poisons that effect neural networks badly without killing a single cell.

    Consider LSD for example, nontoxic by any standard at typical dosage.

    --

    FRA: STFU GTFO
  30. Don't know about nanodots... by Emetophobe · · Score: 1

    I don't know about nanodots, but I've had some experience with microdots when I was younger.

  31. Brain cells and nanodots? Progress marches on. by hey! · · Score: 1

    Having seen the results of mixing brain cells and microdots in the 70s, I shudder to think of the consequences.

    I once sat next to a guy from my dorm at a movie; there was a scene where a couple was sitting at a table and the woman was laughing.

    "Oh, wow!" said my friend, "look how her teeth are spinning around. Like a chainsaw or something."

    "What are you talking about?" I whispered.

    "Her teeth are spinning around!"

    "No they aren't," I replied. "Are you OK?"

    "Oh, don't worry," he replied,"somebody must've salted my food with acid."

    "Some joke," I said, thinking that if somebody did that to me I'd break both their arms. For starters.

    "Nah, it's cool," he replied,"I've done a lot of acid. It couldn't have been much"

    --
    Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
  32. Welcome by xazos79 · · Score: 1

    I, for one, welcome our new rat overlords.

  33. I'll always be a hominid at heart by smchris · · Score: 1

    Ask me what adult genetic modifications I'd like and I can tell you, but the whole brain in a machine interface creeps me out. I blame Babylon 5. Growing the cell/interface lattice from scratch creeps me out even more for some reason. Guess we all have our limits.