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Extinct Ibex Resurrected By Cloning
The Telegraph is reporting that for the first time an extinct animal has been brought back via cloning. The Pyrenean ibex, a type of mountain goat, was declared officially extinct in 2000, but thanks to preserved skin samples scientists were able to insert that DNA into eggs from domestic goats to clone a female Pyrenean ibex. While the goat didn't survive long due to lung defects this gives scientists hopes that it will be possible to resurrect extinct species from frozen tissue. "Using techniques similar to those used to clone Dolly the sheep, known as nuclear transfer, the researchers were able to transplant DNA from the tissue into eggs taken from domestic goats to create 439 embryos, of which 57 were implanted into surrogate females. Just seven of the embryos resulted in pregnancies and only one of the goats finally gave birth to a female bucardo, which died seven minutes later due to breathing difficulties, perhaps due to flaws in the DNA used to create the clone."
We can just patch the damaged or missing segments with frog DNA...
Nature will find a way.
Did we learn nothing from Jurassic Park?
Help! I'm a slashdot refugee.
"one of the goats finally gave birth to a female burrito"?
'cause I sure did.
The mitochondrial DNA will not be from the IBX so what you have is still an hybrid.
Maybe better than nothing but not really bringing the species back.
See my blog http://ilovecookes.blogspot.com/ for light hearted technical information.
I won't goat you, I herd it's dead Jim.
Ewe!
Yo Grark
Canadian Bred with American Buttering
Pyrenean Ibex extinct... again.
That a real Intrepid Ibex
So, this Ibex became the first species to become extinct twice?
do I get me pet Mastadon?
"While the goat didn't survive long due to lung defects this gives scientists hopes that it will be possible to resurrect extinct species from frozen tissue."
That was about how my 8.10 experience went too.
Why is this story from 11 months ago being reported by Slashdot as if it just happened? Could the reason be anything other than sloppy content gate keeping?
But I would suggest that next time a species is down to 30 members, get samples from ALL of them. For all they know, this last one may have had some genetic defect, and pulling DNA from her eye probably didn't help her.
I've been waiting for YEARS for the chance to eat extinct animals! T-Rex Burgers, Bald Eagle Sandwiches, Dodo Egg Omelettes, Saber-toothed McNuggets! Yummmm!
I'm thinking Jurassic Pork. Bring back some extinct hog species and grill 'em up!
MRSH-Recording device, corned beef sandwich with kraut, seafaring bird, and the foamy top of a beverage.
Recognized by the goatee
If you mod this up, your slashdot background will turn into a beautiful sunset!
Except, I suppose, for the defective lungs?
Alexander Peter Kristopeit bought his basement from his mommy for one dollar.
That's important when she's up in Alaska and keeping an eye out on Russia.
1 dinosaur, please!
Steal my band's record! Seriously,
$ lsb_release -c
Codename: ibex
Wooly mammoth? Dodo? Passenger pigeon?
-jcr
The only title of honor that a tyrant can grant is "Enemy of the State."
Actually ressurrecting a goat is not the same as bringing back a T-Rex. But hey, at least we'll be able to feed it, if we ever do bring back the dinosaurs...
http://www.beanleafpress.com
John Hammond: "All major theme parks have had delays. When they opened Disneyland in 1956, nothing worked!"
Dr. Ian Malcolm: "But, John. If the Pirates of the Caribbean breaks down, the pirates don't eat the tourists."
no, no, no, no, no!
try this :
"This just in, Pyrenean Ibex still extinct." </Chevy Chase>
the preceding comment is my own and in no way reflects the opinion of the Joint Chiefs of Staff
"...female burrito..." :)
Let's see...
"...which hovered in the air in much the same way that bricks don't."
Nope. It's not just you.
As mentioned before, this is not an exact clone. The only thing this story proves is that they can create a hybrid animal (nothing new there) and that the researches who did this were dishonest about the product (nothing new there) and that the news media is full of a bunch of dolts with little desire or propensity for actual journalism (nothing new there either). The only thing that was created was 7 minutes of suffering.
I for one, welcome our newly extinct Ibex Clone overlords.
Cloning is becoming more and more advanced. Human cloning will probably be achievable within the next 20 years. How long until Republicans back human cloning as a way to avoid estate taxes???
bad science! There is a reason it is extinct and once this has happened nature will not be reversed. Whatever they come up with, will not be the original species. It is gone forever.
Athiesm is a religion like not collecting stamps is a hobby.
heh, I mis-read it as Piranha Ibex at first. I figured it must be a plot by PETA to let the little buggers fight back.
This issue is a bit more complicated than you think.
The article linked is dated January 31, 2009. At least the article is dated this year...
Don't you see? It's a marketing ploy by Apple!
-- I really need to bleed off some of this
I have a goat herd and trust me when I say there doesn't have to be any flaws in the DNA to lose a baby. I've seen them still born, born too frail to stand up and get colostrum from mom, seen them live for a couple days and then die for no apparent reason. There's a reason goats have babies two and sometimes three at a time. The loss rate can be high, even under ideal conditions. The breed difference could account for it. Maybe the original breed had a slightly longer gestation period than modern goats.
Back in the day I used to help a vet implant zebra embryos in horses. The take rate was a bit higher than that experiment, but we had more embryos to work with. 10% was a pretty good rate for implants and there's a lot of data on horses.
That's our life, the big wheel of shit. - The Fat Man, Blue Tango Salvage
Was it Intrepid?
Maybe you could clone all the known intermediates all the way back and use them. It'd take a while though.
It's like this episode of the simpsons, treehouse of horror XII where Bart casts a frog into a frog/man hybrid and it was a "sin against nature".
I feel like the Ibex that was only alive for 7 minutes probably felt about the same.
Can't we just leave the extinct alone? Some mistakes can't be corrected.
http://en.sevenload.com/videos/qMVhCUs-Simpsons-Harry-Potter-spoof
please, please, pretty please
intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
Dinosaurs still exist. We call them "birds".
In particular, they're the decendents of the clade Maniraptora, which includes velociraptor. Many are still remarkably similar to their ancestors -- for example, compare these reconstructed skull images of oviraptors with modern birds (for example, the cassowary)
As it says in the Constitution, Lenin is in my shower.
Nuclear transfers, no wonder the poor thing died soon after.
Seriously, though, even if they perfect the technique and the beasties survive, and apart from the mitochondrial issue that's been posted already, you'd still have to manage to clone a sufficiently diverse population for it to become self-sustaining again. I doubt there's many extinct species for which we've got several dozen different DNA samples in good condition.
What a depressingly stupid machine.
And what is that reason and why won't nature be reversed?
kurzweil_freak
5th Kyu Genbukan Ninpo/KJJR student
Be the darkness that allows the light to shine.
bad science! There is a reason it is extinct and once this has happened nature will not be reversed. Whatever they come up with, will not be the original species. It is gone forever.
You really are insane.
Or were you joking?
I wonder what ibex tastes like
Support the FairTax
[The nuclear DNA is so high a percentage etc. that a DNA-only transplant might be considered a full reconstruction.]
Also: They can always clone the mitochondrial DNA into something suitable (like goats again) and later harvest eggs with the right mitochondria, insert DNA from members of a wrong-mitochondira reconstruction, and produce new clones with both nuclear and mitochondrial DNA of the species to be recovered.
Fly in the ointment might be if the co-evolving mitochondrial and nuclear DNA had diverged sufficiently between the egg donor and extinct species that the communication between the cell and the mitochondria is hosed and you can't get a viable reconstruction with nuclear DNA only. But this communication is sufficiently simple and conserved that this seems unlikely. You start from a host egg of a closely-related species to avoid a vast number of similar potential screwups between the donor egg's existing machinery (or the host mother's biology ditto) and the implanted DNA's version of the same systems, any of which might make the effort fail. The mitochondria are just one more of the donor's systems (which happens to have its own DNA.)
Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
Jurrassic McRib sandwiches?
http://google.com/search?q=do+ibexes+fear+fire
http://google.com/search?q=do+ibexes+fear+death
http://google.com/search?q=protecting+my+home+from+ibex+attack
(Ibices?)
When they found the first T-wreck, did they invent road pizza?
Back in the day I used to help a vet implant zebra embryos in horses.
Speaking of equines, I'm hoping this will be tried with Quaggas for the extinct DNA donors.
Zebras are essentially a striped wild donkey that is essentially not domesticable. Quaggas were an apparently a close relative that domesticated just fine and were quite useful. But they were allowed to go extinct in the mid 1800s, when the wild ones were hunted to extinction and contact with other parts of the world led the farmers who used quaggas to switch to other equines (think "fad").
Ought to be reasonably easy to pull this with zebras or donkeys for the egg donors and hosts, reconstructing the lost species (for potential breeding and mule-making programs later). There's already a project to "breed them back" from the plains zebra (which they are really a variant of) and there are 23 known stuffed-and-mounted specimens.
Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
Goat gestation period are around 150 days.
Ibex is around 165 days.
Even if you take a healthy Ibex mother and remove the fetus after 150 days, it will have similar lung disability. Lungs being the last thing to develop in a fetus, if you chop off the last few days of fetal development, you're sacrificing lung function. They won't work at 100%, and they'll be way more sensitive to any agitation. It seems to me like a better approach would be to find an animal with a equal OR LONGER gestational period. I don't mean for Ibexes in particular; it just makes sense for any mammal. Try a mountain goat: 180 day average gestation period. Just make sure you bust the little guy out two weeks early.
If humans go extinct and you implant human DNA into a bonobo, you're putting something that takes 280 days to cook into an oven with a 230 day timer. No, it won't be fully cooked when the thing dings - the lungs especially. Premature human babies do survive that young, but we've had a long time and lots of money poured into finding ways to make that happen.
Thanks for the link! I found these instructions to build fsv... worked for me on Ubuntu 9.04.
http://sectio-aurea.blogspot.com/2008/12/3d-file-system-viewer-building-fsv-on.html
Very cool! XD
Do what thou wilt shall be the whole of the Law
Heck, here on /., we keep repeating the same dead jokes. And they keep propagating even with ppl screaming for ppl to quit redoing the same item. Not different than in JP.
I prefer the "u" in honour as it seems to be missing these days.
"Weird Al" Yankovic did not create every parody ever.
The common ancestor we share with the dinosaurs was not itself a dinosaur, but the birds started out as a branch of the dinosaurs. If you consider the word "dinosaur" to be a clade, then they are dinosaurs.
As I recall, they were hunted to extinction for their plumage. Haven't seen anything to indicate whether they were good to eat.
-jcr
The only title of honor that a tyrant can grant is "Enemy of the State."
Isn't Extinct Ibex the next Ubuntu release?
That is one Intrepid Ibex for sure. Maybe they spliced in some penguin DNA? *wink*
We do not share a common ancestor with dinosaurs. We are the descendants of synapsid reptiles, which were largely beaten out in the triassic by archosaurs (the ancestors of all dinosaurs, birds, and crocodilians).
As it says in the Constitution, Lenin is in my shower.
Of course, but they are only far removed cousins of the cool dinosaurs.
You don't think the raptors were "cool dinosaurs"?
BTW, even ratites have very advanced flight adaptations and aberrant skeletons for a dinosaur
Yes, they are not "living fossils". But they are their direct descendants, and are overall quite similar in most regards.
You could as well compare a kiwi with an echidna as they are both tetrapoda.
Tetrapoda is a superclass. Maniraptora is a clade under the suborder Theropoda. Not anywhere close to equivalent.
As it says in the Constitution, Lenin is in my shower.
We do not share a common ancestor with dinosaurs.
Umm, you might want to think about that statement for a while.
Poor phrasing. We do not descend from dinosaurs. Birds do.
As it says in the Constitution, Lenin is in my shower.
I'm just saying....
Please do not read this sig. Thank you.