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Silicon Valley Is Too Focused On Taking the Easy Path in Health Care (cnbc.com)

Silicon Valley investors are increasingly looking at health space, but they are mostly eyeing for opportunities on the fringes of the traditional health care system to avoid long and complicated regulatory cycles, an analysis on CNBC shows. As a result of this, these start-ups will not help low-income and chronically ill patients who need innovation most. From the article: Founders often talk about about how challenging it can be to break into the multi-trillion dollar medical sector. Health care startups face regulatory hurdles, long sales cycles and a high burden of proof -- and that means it can take more than a decade to make a return. As a result, many venture-backed entrepreneurs are looking instead at opportunities on the fringes of the health care system, such as cash-only health services that don't require insurance or tests and apps that aren't regulated by the U.S. Food and Drug Administration. For tech investors, these opportunities hold the chance of an outsized return in five years or less. That often valuations on par with consumer Internet start-ups. [...] Many entrepreneurs acknowledge this, but justify their approach by promising to focus on more at-risk groups once they've nailed the product.

85 of 135 comments (clear)

  1. Brilliant by stephenmac7 · · Score: 4, Insightful

    They've figured out that the regulations they're always pushing for make it near-impossible to compete with established companies and hurt innovation.

    --
    "No man's life, liberty, or property are safe while the legislature is in session." -- Judge Gideon J. Tucker
    1. Re:Brilliant by stephenmac7 · · Score: 1

      I'm aware that I accidentally submitted the same comment twice. Sorry about that -- wish Slashdot would let you delete your comments.

      --
      "No man's life, liberty, or property are safe while the legislature is in session." -- Judge Gideon J. Tucker
    2. Re:Brilliant by Luthair · · Score: 3, Insightful

      I have some snake oil it cures cancer and makes you live 50% longer. Would you like to buy some?

    3. Re:Brilliant by Anonymous Coward · · Score: 2

      Some regulations do - the patent system is an example. The system was actually designed to help innovation, however in its current form it harms innovation more.

      However, regulations in some actors are needed in order to protect you from greedy profiteers that would sell you about anything to make a quick profit. Healthcare is an example.

    4. Re:Brilliant by Anonymous Coward · · Score: 1

      I've never met this guy before but I can confirm it cured my cancer and gave me a six pack.

    5. Re:Brilliant by cayenne8 · · Score: 4, Insightful

      They've figured out that the regulations they're always pushing for make it near-impossible to compete with established companies and hurt innovation.

      Yep....

      I think the reply to them is pretty much, "Duh".....

      That's the way it is with overly onerous regulations...it ONLY helps the big guys that can afford to fund a full department dedicated to only the regulation and documentation side of the business.

      It is understandable in some respects, due to this being medicine...lives can be affected by errors, but the regulations aren't just targeted at direct patient interaction...but many other things.

      It does bring up, however, questions as to how some parts are SO over-regulated, yet direct patient contact items, like heart regulators, insulin and other drug pumps are able to be put out there, without even *basic* encryption, so as to protect patients from being literally hacked, and possibly killed.

      --
      Light travels faster than sound. This is why some people appear bright until you hear them speak.........
    6. Re:Brilliant by elrous0 · · Score: 5, Interesting

      While I might normally be inclined to agree with you, I have to point out that regulation in the healthcare industry is there for a very important reason. When you're dealing with human bodies and human lives, you need a very carefully regulated system to prevent someone's mistake from turning into a disaster that costs a lot of lives or causes a lot of harm.

      For example, those annoying regulations that require extensive clinical trials and testing of new drugs are there for a very good reasons. They're in place to prevent disasters like what happened in West Germany and the UK in the 1950's, when the drug Thalidomide was okayed for sale without adequate testing.

      --
      SJW: Someone who has run out of real oppression, and has to fake it.
    7. Re:Brilliant by Kohath · · Score: 4, Informative

      It's not so much regulations. Health care needs regulations. It's that US regulators are notoriously bad at it. My friends in the medical device business do most of their work in places like Germany and other Northern European countries because the regulators are strict, but they do their jobs predictably and in a timely manner. They shun the US because the regulators are sloppier and everything takes forever in the US.

    8. Re:Brilliant by jeff4747 · · Score: 1

      Yes, including innovation like snake oil and Thalidomide.

    9. Re:Brilliant by known_coward_69 · · Score: 1

      So what happened when Vioxx was found to cause heart attacks? people said the regulators responsible should have been fired

    10. Re:Brilliant by Kohath · · Score: 1

      Why are you complaining about a single drug approval from almost 20 years ago? Unless they reject every drug, they're going to make some errors by approving drugs they shouldn't approve sometimes. You want new drugs, it's never going to be risk free.

      And you are responding to a post where I say US regulators are bad at it. And your point is that ... they made a mistake once. Yes.

    11. Re:Brilliant by MightyYar · · Score: 5, Insightful

      Regulations are good and necessary to a free market, but established players tend to get regulations which are not good or necessary for a free market tacked on. Governments get in on the action to try to extract money and craft perks for their special interests. Sometimes the unnecessary regulations are simply the result of well-meaning officials who think they are improving upon what a free market could deliver, but in reality have the effect of freezing the state of the art.

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
    12. Re:Brilliant by interkin3tic · · Score: 5, Insightful

      It is understandable in some respects, due to this being medicine...lives can be affected by errors, but the regulations aren't just targeted at direct patient interaction...but many other things.

      Just to be clear, interactions with the patient are only a tiny slice of what can kill a patient. Making sure a drug companies' formulation facilities are bacterial-free is pretty far removed from patient interactions.

      If you're making a test blood poisoning, that's never going to be put into a patient. You want to be sure the raw components are bacterial free though obviously or else the tests are going to be useless and doctors won't know if they're facing blood poisoning or something else. To make sure the raw components are bacterial free you want the facilities to be bacterial free. If you find bacteria, you need to shut down production while you sterilize everything. That's a huge cost.

      If you're trying to start selling a cheaper test and you get a report saying you need to shut down production for a week, any sane business is going to say "Hmm... that will kill us... is it REALLY necessary to shut down if we have three bacterial colonies on a single plate? Lets talk to the undergrad who reported the test, ask him if he really wants everyone to lose their jobs? 'Isn't it maybe possible you accidentally sneezed on the plate?'"

      Easy to justify: you know your facilities are clean, you spend a shit ton of money cleaning them. And that's just like the doors! That's not even the production vats! No way is the whole thing contaminated. Plus these aren't even going to go into people... You do testing of all the lots of blood tests, you'll know if they're compromised... And besides, any doctor worth his salt is going to be able to identify SEPSIS without a %100.00000000 accurate blood test, it's so common! Fire the kid and ship it.

      Regulations are necessary especially when it's not directly interacting with a patient. Yes they are huge barriers to efficiency, granted, but healthcare is simply not a place the free market works at any level. The end result is not sales, it's literally life or death. Society simply does not tolerate that. Investors who get into healthcare and deceive themselves into thinking it is a free market deserve to lose their money. Politicians and pundits who try to reform healthcare towards "free market" are deceiving themselves and or the public, and deserve to be thrown out of their jobs hard. If they try to exempt themselves from such "free market" solutions while subjecting everyone else to it, they deserve literal crucifixion even if they do claim it's just a reconciliation loophole they'll totally close later.

    13. Re:Brilliant by SScorpio · · Score: 1

      A six pack of what? Curing cancer is great, but I might still think twice if I'm stuck with a six pack of natty light.

    14. Re:Brilliant by Archangel+Michael · · Score: 3, Insightful

      All regulations do. The fact that we don't document every regulation stifles innovation (And spurs innovation in other areas), we don't know exactly where the wash is.

      Every regulation takes from production, and transfers it to compliance.

      FYI, this is neither "good" nor "bad", it just is. Some regulations are needed, others just get in the way, duplicate other regulations, run counter to others etc. The fact that we rarely look at the consequences for regulations, and make adjustment, enhancements, and revoke so very few ineffective ones is my actual frustration in the whole process.

      --
      Agent K: A *person* is smart. People are dumb, stupid, panicky animals, and you know it.
    15. Re:Brilliant by jellomizer · · Score: 1

      Changing Regulations are worse for innovation, than the number of existing ones. The problem is we got ACA, we can deal with this, then the Republicans want to dump it and replace it. So all the systems that have been made, tested and optimized for the old way, will need to be rethought, remade, and retested...
      As a Health Care IT Worker, I have a bunch of nice of haves that will actually lower cost and improve care that I have just started, if they are going to take such regulations away or change them. Then I will need to stop them and go back and fix what has been finally set for working.

      As for this article. Silicon Valley doesn't like to work on boring technology. Health Care technology is decades old, and it just needs some boring old redesign to more modern processes... What is needed will not look new and innovative to investors. It will be tough to get staff excited in doing this work. Especially in the west coast. In the East Coast is where the boring IT work is done.

      It isn't about easy path, but there are many 900 lbs guerrillas that needs to addressed, and not with a shiny new software, but by sitting down and doing the drudge work, or changing configurations, creating additional interfaces to other systems, cleaning up old data. Connecting relationships between data. And analysis of existing data.

      Giving Doctors a mobile app, will just give a shiny tool without fixing the fundamental problems.

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    16. Re:Brilliant by Shark · · Score: 1

      You shall not infringe on the sacred subscription model of big pharma lest you be regulated out of existence. Curing people is a sin against the holy drain of capital. A life that goes on without buying the divine treatment is a life lost and crime against the revenue-stream gods.

      --
      Mind the frickin' laser...
    17. Re:Brilliant by HiThere · · Score: 1

      The problem with your comment is that you are assuming the two used of "they" refer to the same groups of people (though there *is* overlap).

      --

      I think we've pushed this "anyone can grow up to be president" thing too far.
    18. Re:Brilliant by virtualXTC · · Score: 1
      I call BS!

      Some regulations actually encourage innovation (carbon credits). Moreover, without truth in advertising / some burden of proof that what you are putting out there in healthcare actually works, it's easy for a large company (l'll choose Merck since they seem to have no problem publishing fake data to this end) to claim they've made a drug that cures a particular disease causing funding in that field to evaporate.

      Similarly, since there are no non-profit pharmaceutical manufacturers (due to the sheer cost), the issuing of drug patents (a form of regulation) are they only way to incentive the huge finical risk that a large scale (burden of proof) trial entails, and subsequent manufacturing equipment costs. As a researcher I wish this wasn't the case, but it seems even generic drug makers won't enter the market for a patent-free without some idea of what the market capacity is.

    19. Re:Brilliant by guises · · Score: 1

      '"They" have figured out that the regulations "they're" always pushing for...' Who is "they"? That's a rhetorical question, this is obviously another smear on liberals. The great enemy.

      Setting aside the fact that "they" are not a monolithic entity, so "they" don't exist, there is another way to read the summary above: where it says that these startups don't pursue mainstream medical business opportunities because "it can take more than a decade to make a return" you could read that as an issue with the regulations in place - we should be doing more to accommodate the silicon valley get-rich-quick business model. Or, you could read that as an issue with their business model - if they want to make money where other peoples' lives are on the line, they should be adapting their business model to meet the regulations designed to protect those lives.

      In other words, maybe demanding massive returns in five years or less isn't the best way to approach every problem?

    20. Re: Brilliant by jopsen · · Score: 1

      It also showed that the drug manufacturers are far more proactive and effective than the FDA at ensuring patient safety.

      As it should be... If someone sets your house on fire and the fire-alarm doesn't work, you first blame the guy who lit your house on fire... Rather than blaming the fire-alarm.

      On topic of regulations it makes no sense to argue that they are all bad, or they all stifle innovation or competition.. Lots of regulation have positive effects. It's just that Americans have a hard time seeing it as anything other than black/white.

      Sorry, the world doesn't reduce to good vs. bad.


      In field of medicine US regulations says new drugs must be better, EU regulations says they must be better or equal. This has pros/cons, you can bring newer drugs to market in the EU, even if they are just cheaper... In the US it's not enough to be cheaper your new drug must better.
      Obviously, the intention is to force development of better drugs. Granted the downsides is higher burden of proof.

    21. Re:Brilliant by MightyYar · · Score: 1

      I don't think the statement that "regulations are good an necessary to a free market" is nearly as "obvious" to others as it is to you. Thanks for really adding to the discussion.

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
    22. Re:Brilliant by stephenmac7 · · Score: 1

      That may be true, but how many people die when the FDA fails to approve drugs on time? Why not just have incentives to avoid hurting people rather than telling them how to do it? If someone falsely advertises, they can be sued for fraud. If their drug has X side effect (maybe even death), they can be sued for all damages caused by their nondisclosure of said side effects. Federal regulation is not the most effective way to keep people safe. The problem is that we have an easy time imagining what would happen if the FDA doesn't exist -- "snake oil," unsafe drugs, etc -- but we fail to see what innovation didn't happen or what lives weren't saved because of the FDA.

      --
      "No man's life, liberty, or property are safe while the legislature is in session." -- Judge Gideon J. Tucker
    23. Re:Brilliant by ArmoredDragon · · Score: 1

      In this case, I think the FDA would benefit from making it easier to start a clinical trial, i.e. speed up its evaluation process, allow to skip animal testing, etc. But in exchange for that, counseling for informed consent must be much more rigorous, namely telling them that they risk loss of life, limb, eyesight, or other bodily functions, and that they will have limited legal recourse if anything goes wrong.

      Terminally ill patients could be encouraged to sign up for phase 1 trials, and so long as nothing goes horribly wrong they can quickly move to phase 2, then phase 3, and maybe a 4th phase to rule out any long-term effects, but make the 4th phase open to unlimited participants.

    24. Re:Brilliant by Actually,+I+do+RTFA · · Score: 1

      Capital costs exist in any industry. You need to own a mine to get into mining. You need to own land to farm. And you need to prove you're not selling rat poison in the pills. I don't see what the issue is.

      I mean, its possible that the regulations are overreaching. But it seems far more likely they are a reaction to something.

      --
      Your ad here. Ask me how!
  2. the problem... INVESTORS.... by starblazer · · Score: 4, Insightful

    I bet you three fiddy that Silicon Valley wants to tackle these problems, but its the INVESTORS that control the pocketbooks of Silicon Valley that don't want to take the risk on. The long game, pfffft, what's that? Humanity? Pffft!

    1. Re:the problem... INVESTORS.... by fustakrakich · · Score: 1

      Really. This story even isn't about 'health care'. It's about investment risks and opportunities. And as soon as the subject of 'valuations' comes up, you should run for the hills.

      --
      “He’s not deformed, he’s just drunk!”
    2. Re:the problem... INVESTORS.... by jimbolauski · · Score: 2

      If the employees are good with going without a paycheck for a year or so while all the regulations are met then take a pay cut because they don't want to be accused of gouging their customers I'm sure investors would jump on board.

      --
      Knowledge = Power
      P= W/t
      t=Money
      Money = Work/Knowledge so the less you know the more you make
    3. Re:the problem... INVESTORS.... by Anonymous Coward · · Score: 1

      These investors pump MILLIONS into these tech ventures, half of it wasted on real estate and furniture. They can not only afford to give them fair wages, they can also afford to wait for results.

    4. Re:the problem... INVESTORS.... by Shatrat · · Score: 1

      I would take that bet. I've had the misfortune of supporting a major Silly Valley corp that was trying to 'innovate' an existing industry.There was an attitude that technology is magic and that they would be able to come in and in 18 months be better at that industry than companies which have existed for a century. The individual engineers and project managers are also not interested in anything that isn't 'disruptive', including hard work and studying their competitors. They didn't seem to grok the basic concept that if you don't understand something well enough to do it manually, you don't understand it well enough to automate it.

      --
      09 F9 11 02 9D 74 E3 5B D8 41 56 C5 63 56 88 C0
    5. Re:the problem... INVESTORS.... by jimbolauski · · Score: 1

      You are awful generous with other people's money.

      --
      Knowledge = Power
      P= W/t
      t=Money
      Money = Work/Knowledge so the less you know the more you make
  3. F*ck the poor by mveloso · · Score: 2

    Why sell to people with no money?

    1. Re:F*ck the poor by i_ate_god · · Score: 1, Insightful

      Because the US is a third world country.

      The modern countries on this planet provide health care instead of selling it.

      --
      I'm god, but it's a bit of a drag really...
    2. Re:F*ck the poor by mveloso · · Score: 2

      "Modern countries" have their free healthcare paid for by high taxes and government redistribution. That's one way to do it, but not necessarily a better way.

    3. Re:F*ck the poor by Ungrounded+Lightning · · Score: 1

      Because the US is a third world country.

      Sorry, the US is still a first-world (NATO-aligned) country (although Trump might have changed that if the threat of the US dropping out hadn't caused the deadbeat members to start paying toward their share of the costs.)

      Of course if you're using the evolved meaning of "poor, economically peripheral" or "mass of underpaid or unemployed serfs under the domination of a Fearless Leader and/or an elite", the US is on the track to that, by replacing the lower class workers with cheap, illegal, immigrant labor and the middle class workers with H1-B effectively indentured servants.

      The modern countries on this planet provide health care instead of selling it.

      Actually, obtaining necessities via a market incentivizing their production and competition creating redundancy and driving down prices IS the "modern country" approach, dating from "Adam Smith" a couple centuries back.

      Having it provided to the serfs by the rulers is a legacy of noblesse oblige, where the royalty of Europe (and their predecessors), having confiscated all the wealth and productivity of the serfs, were obliged to provide them with enough health care to keep them healthy enough to keep producing more wealth. Just enough more to keep the nobles living "like kings" and able to hold off takeover of their serfs by their neighbors, of course. Not enough fo the serfs to live comfortably.

      --
      Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
    4. Re:F*ck the poor by Anonymous Coward · · Score: 1

      >You certainly don't go into that career for only altruistic reasons....

      A lot of people most certainly do. Do you really want a doctor that is concerned about money more than taking care of you?

      > you don't get the best people that way.

      Doctors Without Borders, USAID, CDC, UNICEF all disagree with you.

    5. Re:F*ck the poor by stabiesoft · · Score: 1

      Single payer would be cheaper. Private insurance runs around a 20% admin overhead. Even if you do not believe the 1.5% admin rate quoted for medicare, I am pretty confident it is much less than private. And if single payer could get rid of the 7 figure hospital exec's which are not part of the insurance overhead, even better. So we would get rid of 2 non-participatory costs (insurance execs and hospital admins) who contribute zero to keeping people alive.

    6. Re:F*ck the poor by Bob+the+Super+Hamste · · Score: 2

      Come on now. If it weren't' for those executives healthcare would be even more expensive. They try and cut costs as much as possible to ensure that every department shows a profit. Even the guys in maintenance. /sarcasm

      I wish I weren't joking but my father (biomedical repair technician) has had the joy of dealing with several managers like this over the years. One questioned why they had so many different spools of hosing and suggested that they order just what they need. The problem is that they basically do keep on hand what they need as that stuff has predefined replacement intervals so since they know they have X machines that take Y feet of Z hose N times a year they have a pretty good idea of how much hose they need. Same thing with other parts and components. That manager wanted to turn the bio meds into a profit center instead of a cost center. There were other cases where managers got into a pissing match over what repair should be done and who was going to pay for it. Like the one where if the device was sent back to the manufacturer it would be charged to the surgery department at like $5000 but if the bio meds opened the device and replaced the broken component it would only cost $700 but would be charged to the bio med department. That argument took a couple of weeks to resolve and required the intervention of a VP.

      --
      Time to offend someone
    7. Re:F*ck the poor by Kohath · · Score: 1

      So still super expensive then. Why should we switch to a system most people don't want to save a couple percent?

      ... 7 figure hospital exec's ...

      And added government worker pension costs will be many times that. Pensions don't provide patient care either.

    8. Re:F*ck the poor by HuguesT · · Score: 1

      Nice FUD, sir.

      Demonstrably socializing medicine is the better way, evidence is here.

      Best.

    9. Re:F*ck the poor by HuguesT · · Score: 1

      Nice try quoting bloomberg, like they are a perfectly neutral observer there. *Just* getting rid of the overhead of having multiple inefficient systems competing with each other in an anti-competitive market would be a bonus. Then there is the matter of the single payer being able to negotiate better medicine practices and prices. This is what nearly every country in this world does. The champion is Japan. Notice they have a lot of centenarians there.

      Also, why should the US be like other countries when most people in the US want a more US-like system?

      Ignorance maybe ?

    10. Re:F*ck the poor by i_ate_god · · Score: 1

      > Of course if you're using the evolved meaning of "poor, economically peripheral" or "mass of underpaid or unemployed serfs under the domination of a Fearless Leader and/or an elite", the US is on the track to that, by replacing the lower class workers with cheap, illegal, immigrant labor and the middle class workers with H1-B effectively indentured servants.

      It was just an intentional insult.

      > Having it provided to the serfs by the rulers is a legacy of noblesse oblige, where the royalty of Europe (and their predecessors), having confiscated all the wealth and productivity of the serfs, were obliged to provide them with enough health care to keep them healthy enough to keep producing more wealth. Just enough more to keep the nobles living "like kings" and able to hold off takeover of their serfs by their neighbors, of course. Not enough fo the serfs to live comfortably.

      > Actually, obtaining necessities via a market incentivizing their production and competition creating redundancy and driving down prices IS the "modern country" approach, dating from "Adam Smith" a couple centuries back.

      Which explains why Americans pay more for their healthcare than Canadians do... wait, was that your point? I'm not sure.

      > Having it provided to the serfs by the rulers is a legacy of noblesse oblige, where the royalty of Europe (and their predecessors), having confiscated all the wealth and productivity of the serfs, were obliged to provide them with enough health care to keep them healthy enough to keep producing more wealth. Just enough more to keep the nobles living "like kings" and able to hold off takeover of their serfs by their neighbors, of course. Not enough fo the serfs to live comfortably.

      Well written FUD. If all my wealth was confiscated, then how did I buy this computer to write this message on?

      --
      I'm god, but it's a bit of a drag really...
    11. Re:F*ck the poor by david_thornley · · Score: 1

      Based on 2014 figures (the latest I found when I looked), US per capita health care is three thousand dollars more expensive than the next most expensive one (Switzerland). I think saving most of a trillion dollars a year does count as less expensive, and I think most people would want less expensive health care.

      Some people say we can't do what every other developed country in the world already does. I think those people are dishonest or spineless defeatists.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    12. Re:F*ck the poor by Kohath · · Score: 1

      Based on 2014 figures (the latest I found when I looked), US per capita health care is three thousand dollars more expensive than the next most expensive one (Switzerland). I think saving most of a trillion dollars a year does count as less expensive, and I think most people would want less expensive health care.

      Some people say we can't do what every other developed country in the world already does. I think those people are dishonest or spineless defeatists.

      If you read the article, you will see that countries don't cut health care costs. They only have lower costs because they never got high to begin with. But going back in time isn't really an option.

      You can name-call anyone you want, as much as you want. Do you think that will get health care workers to say "yes" to large pay cuts? Do you think it will convince voters and politicians to listen to you instead of doctors and nurses?

    13. Re:F*ck the poor by david_thornley · · Score: 1

      What I am saying is that every other country in the world has much lower health care costs, and that many of them have better health care results. I'm also saying that the US can accomplish pretty much anything any other country can accomplish. I didn't think those things were all that controversial.

      That's a Bloomberg editorial, and I haven't been impressed with them in the past. It also says it would be difficult to get lower health care costs, which is reasonable. It ignores many of the costs that other health care systems really don't have, such as immensely high prices for vital drugs and a massive insurance industry.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    14. Re:F*ck the poor by Kohath · · Score: 1

      No country has significantly reduced health care costs.

      Yes, if the US could go back in time 100 years, perhaps we could keep health care costs from rising like other countries have succeeded in doing. But going back in time is not an option.

    15. Re:F*ck the poor by david_thornley · · Score: 1

      If we were to streamline the health insurance industry, we'd save money on health care. If we had some sort of negotiation on drug prices like other countries do, we'd save money on health care. Doing these things would significantly reduce health care costs. It wouldn't get us anywhere near second place, but it would be significant savings.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    16. Re:F*ck the poor by Kohath · · Score: 1

      Some money might be saved. There are probably some studies for how much. Drugs are less than 10% of the total health care cost, and if changes cause fewer therapeutic drugs to be developed you'd see other care costs rise as a result.

      Realistically, it would be hard to make the case for big changes based on a one time cost saving of 5% or so. That's about 1 year of health care inflation. Maybe 2 years.

      The main point is that there are no easy wins and no big wins. You can tell a story about much lower costs by making a few changes, but that's not going to happen in reality. We don't live in a story.

    17. Re:F*ck the poor by david_thornley · · Score: 1

      Health insurance administration is a big cost also.

      I'm not saying that it would be easy, but we could arrive at approximate parity with the second-most-expensive by reducing the increase in health care costs, which can't go up faster than total wealth indefinitely.

      I also really hate the idea that the US can't do something every other developed country does as a matter of course, so I'm going to look for ways to accomplish it.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
  4. The future is in offshore data processing by xtal · · Score: 1, Insightful

    The current situtation in healthcare is stupid.

    I sent my genome to a server in eastern europe to get a detailed health report because the FDA won't let 23andme present all of the information. Doctors are actively fighting this democratization of information. Fuck them.

    AI and machine learning have done a better job at diagnosis than humans for decades, but aren't widely used. WHY?

    Fuck the system. I will get the images, and the data - or sensors that I own will - and they will be processed outside of the reach of the FDA.

    Procedures? Medical tourism is a thing.

    Nobody has a more strongly vested interest in me being alive than..me.

    The internet is coming for medicine, the same way it came for software "sales", music, movies, and retail.

    What a time to be alive!

    --
    ..don't panic
    1. Re:The future is in offshore data processing by Anonymous Coward · · Score: 1

      You've sent you genome to a country in Eastern Europe? That's really dumb. And I am an Eastern European.

    2. Re:The future is in offshore data processing by jeff4747 · · Score: 5, Insightful

      I sent my genome to a server in eastern europe to get a detailed health report because the FDA won't let 23andme present all of the information.

      That's largely because the information 23andme wants to present has not been proven to be true.

      So....fuck the system for trying to prevent 23andme from lying to you, so that you don't go on a medical vacation to treat a disease you don't actually have.

      Makes perfect sense.

    3. Re:The future is in offshore data processing by xtal · · Score: 1

      Promethease, by the SNPedia guys. I'm not that worried about my dataset. I'm not that special, neither are you.

      --
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    4. Re:The future is in offshore data processing by tepples · · Score: 1

      That's largely because the information 23andme wants to present has not been proven to be true.

      Which in turn is because nobody has suggested an efficient way to fund said proof.

    5. Re:The future is in offshore data processing by real+gumby · · Score: 1

      Typically life science startups use, you know, VC money to pay for such proof. 23&me just couldn't be bothered.

    6. Re:The future is in offshore data processing by jeff4747 · · Score: 1

      OK, so, given that there are billions of possible genetic variants that could potentially affect a person's health, are you proposing that there need to be billions of these "well-controlled studies"?

      Nope.

      What 23andme wants to claim is if you have genetic variant X, you are more likely to end up with disease Y. That only requires testing variant X. Not all other variants.

    7. Re:The future is in offshore data processing by jeff4747 · · Score: 1

      They state right on their home page that nothing they provide should be used to treat any disease.

      So...they're admitting to fraud?

      If their tests are useless as claimed in their EULA, what exactly are they selling?

    8. Re:The future is in offshore data processing by jeff4747 · · Score: 1

      Anyway, the information that 23andMe was providing was current scientific consensus "proof"

      Some of the information is. Some isn't. The FDA is requiring 23andMe to only provide the information with proof.

    9. Re:The future is in offshore data processing by tepples · · Score: 1

      As I understand it, venture capitalists tend to be unwilling to fund clinical trials that don't result in a patent or other exclusive rights that keep free riders from unfairly benefiting from the VC's investment.

    10. Re:The future is in offshore data processing by real+gumby · · Score: 1

      As I understand it, venture capitalists tend to be unwilling to fund clinical trials that don't result in a patent or other exclusive rights that keep free riders from unfairly benefiting from the VC's investment.

      Yep, that's how it works. And diagnostic companies manage to get funded and deal with this.

      There's a lot of art in the med field about how to structure things in a way that are protectable.

  5. Most startups seem focused on weeding out the weak by xxxJonBoyxxx · · Score: 5, Insightful

    Most of the "health" startups seem focused on weeding out the weak, as in "let X voluntarily track your activities and single you out for unaffordable health premiums if you aren't young/healthy/kid-free enough to meet our wearable device targets." So yes, if it seems that the chronically ill are being pushed off the map, well it's by design.

  6. no, really by paiute · · Score: 3, Insightful

    " promising to focus on more at-risk groups once they've nailed the product"

    I totally believe you, pal.

    --
    If Slashdot were chemistry it would look like this:Cadaverine
  7. realistic expectations by phantomfive · · Score: 1

    "Silicon Valley" is going to do things that are profitable. Expecting anything else is unrealistic, as nice as it would be.

    --
    "First they came for the slanderers and i said nothing."
  8. Not sure why this is news.... by Drewdad · · Score: 1

    Business wants easy way to make money. News at 11.

    They just need to admit to themselves that it's about the money. Once they nail their "low hanging fruit," they're going to diversify... by finding more low-hanging fruit.

  9. Retail, social media and gigging. by hey! · · Score: 1

    They aren't brain surgery. They aren't even primary care. All that model disruption business is about sweeping away old, inefficient systems that support simple and relatively discrete transactions: systems that sell me a book; give me a ride from A to B; or provide someone to mow my lawn for me. The entrepreneur in these scenarios focuses on achieving speed, scale and convenience rather than managing complex, ongoing and labor-intensive processes.

    Healthcare services may be inefficient and mind-numbingly bureaucratic, but people are going to be intensely skeptical of anything that aims to shut down their local hospital or physical therapy clinic. The one core function that certainly could be constructively disrupted using the standard Silicon Valley model is prescriptions: drugs and medical devices. Those areas are fiercely defended by their respective industries, who have maximizing consumer expenditure down to a science.

    The one success story in the article doesn't really fit the classic Silicon Valley creative destruction narrative. It amounts to what is called in other parts of the country "concierge medicine", but with some added high-tech frippery to appeal to well-heeled Bay Area clients. There are lots of gaps in the US health care coverage, but unfortunately they mostly center around under-serviced poor and rural populations. Lower cost services would be welcome in those segments, even if substandard.

    --
    Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    1. Re:Retail, social media and gigging. by jopsen · · Score: 1

      One could also imagine 24x7 on-demand doctors appointments with emergency room like capabilities... But with some Uber-like must make an appointment to get around regulation that you have to accept everybody in an emergency room... Hence, effectively creating an emergency room service that is unavailable if you don't have insurance or ability to pay your co-pay.... there by lowering the cost of running the emergency room.

      Note: I kind of hope such startup doesn't happen... But some of the Silicon Valley style disruption like Uber, certain has a backside to it...

  10. The long game's too risky by rsilvergun · · Score: 2, Interesting

    There's an excellent chance we're going to move to single payer in the next 20 years. The big money isn't in care, it's in being a middle man that skims 10% off the top. A shift to single payer gets rid of most if not all of those middle men...

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  11. Re:tech innovation causes chronic ills? by alvinrod · · Score: 3, Informative

    I'm not sure where you get that idea from. Infant mortality rate was through the roof in primitive societies and as soon as humans moved from nomadic tribes and started building cities, the chronic diseases of civilization became widespread. Up until recently, diseases such as cholera, polio, small pox, measles, etc. were extremely common and were only made rare or eradicated through innovation. Sure back in primitive societies, if you didn't die early in your life you could certainly live to be 80 and I'll grant that people were on the whole healthier because almost all work involved physical labor and even if you had the equivalent of an office job, you still needed to walk to work. However, the chances of any person actually living to 80 was far, far lower. If the various diseases and lack of treatment didn't kill you, invading neighbors would probably do it quite well. So unless you're proposing we abandon civilization and go back to hunter-gatherer groups, your assertion is just wrong.

    Tech innovation has done more for the poor having healthcare than anything else. Even safety nets can't provide services to everyone that haven't been invented or are incredibly costly. Just look at the positive outcomes of Golden Rice in ensuring that some of the world's poorest don't suffer from conditions due to vitamin A deficiency.

    If you don't think its fast enough, you are free to start your own company to rectify the situation. Or is everything just someone else's problem?

  12. Problem is lack of public beta by tepples · · Score: 1

    One problem with snake oil is that not all snake species produce eicosapentaenoic acid (EPA). This led some snake oil makers to end up producing ineffective products. So long as you can document that it's from a snake species whose oil is rich in EPA, I'll buy.

    In areas where the Chinese water snake isn't available, producers switched to imitation snake oils with other ingredients, some of which have since been proven effective. Brands have included Stanley's (capsaicin/camphor), Vicks VapoRub (camphor/menthol), Capzasin (capsaicin), and ActivOn (menthol). The famous ruling against Stanley's in the Rhode Island District Court was mostly that it wasn't clearly marked as an imitation with different active ingredients.

    But the other problem with snake oil is how regulations handle claims not yet proven. Silicon Valley relies on public beta before wide release. But currently a drug product can't reach the market until it's both safe and effective. There's a "supplement" marketing regime where safety is guaranteed and effectiveness is "as is," but there appears to be no "public beta" regime to sell something as a "supplement" between when it is proven safe and then switch to "drug" marketing once it is proven effective.

    1. Re:Problem is lack of public beta by tepples · · Score: 1

      "Public beta" for software generally doesn't kill people.

      If your concern is safety, have a private trial for safety and a public trial for efficacy.

  13. What a nonsense article by real+gumby · · Score: 1

    I have appeared before the FDA, discussing a testing protocol for a drug we were designing...when I was the CEO of a Silicon Valley VC-backed pharma company. The article even quotes a partner from NEA which is a life science investor in addition to being a tech investor.

    Sure, some people try for easy wins...why not? Some people don't do their homework too -- and not just in the life sciences. And some people (looking at you, 23 & me), get the benefit of the FDA bending over backwards to try to allow them maximum freedom to experiment within the consrtraints of the law, and still don't do their homework, and cry victim when they finally have to deal with making no effort to prove the validity of their claims.

    And then the article quotes one company that -- oops -- failed to do its homework.

    1. Re:What a nonsense article by real+gumby · · Score: 2

      Genetic variants are different from drugs. For one things, there are billions of genetic variants.

      Currently the FDA is trying to apply drug validation studies to genetic variants. That's like requiring cars to have proper horse shoes.

      So, umm, this is not the case. Do you have any idea how the non-ag side of the FDA actually operates?

      When you go for approval you define the criteria. "All" you have to show is that you will show statically valid evidence that your claims are plausible. Sometimes the Agency wants some specific proof (e.g. they may ask that you use a specific animal to verify a specific procedure or organ consequence) or may want an additional test because they know some classes of can compounds have characteristic issues. But in general they don't dictate anything. Oh yeah, for a treatment there are outcome criteria, but you are mostly the origin of those as well.

      Diagnostics are simpler to approve than devices, which tend to be simpler to approve than drugs, which to some degree are simpler than biologics. Each division has its own specialists. And the so-called "billions" of genetic cases are a red herring -- just consider the complex consequences of introducing organic compounds into the body.

      Disclaimer: I am not a geneticist, and have not gone for any diagnostic approval, though I am an advisor to a couple of companies that have. But apart from my own experience in the small molecule domain, I do know most of 23&me's regulatory team socially, and we do talk about work. So I know generally what issues they face.

  14. Hype, appy apps, and perpetual beta by swb · · Score: 2

    ...doesn't cut it in the realm of health care.

    Silicon Valley may be noodling around the margins, but it's probably less because of the "onerous regulation" than the empty product they peddle not being able to live up to the regulations and cope with the existing complexity.

    They're not showing up to a business sector that has been moribund and antiquated for decades, they're showing up to a business sector that has been highly computerized for decades, so in some sense they're competing against their Silicon Valley neighbors, too.

    And too much of Silicon Valley "innovation" is just empty bullshit, an appy app, perpetually in beta, and lots of hype. Regulation means following rules, audits to make sure you're doing that and actually delivering something of substance.

  15. Theranos will save us! by Kludge · · Score: 1

    That's largely because the information 23andme wants to present has not been proven to be true.

    Details, details!
    We need more startups like Theranos to save our healthcare system.

  16. FDA fights medical break throughs by micahraleigh · · Score: 1

    If you want to distribute a new life-saving medical breakthrough it has to go through (on average) 20 years of trials.

    Which YOU pay for out of your pocket.

    IF it succeeds you get to use it for (on average) 5 years before it goes to your competitors. They get access FOR FREE.

    So WHY would anyone ever come up with a new break through?

    People are dying because the federal government via the FDA PUNISHES success and helping people.

    I hear the FDA is corrupt, but even if it isn't, disbanding it would save many, many lives.

  17. Just do Single Payer by WillAffleckUW · · Score: 1

    Single Payer Healthcare works.

    It's cheaper.

    It's Medicare For All.

    The vast majority of democracies with good GDP do it.

    We should too.

    And it's way way way cheaper.

    Did I mention the cheaper part?

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    -- Tigger warning: This post may contain tiggers! --
    1. Re:Just do Single Payer by russotto · · Score: 1

      Oh, yeah, absolutely. It's the government I think of when I want something inexpensive and high quality.

    2. Re:Just do Single Payer by WillAffleckUW · · Score: 1

      Unlike you, I've worked in both sides. Private is more expensive.

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      -- Tigger warning: This post may contain tiggers! --
  18. Re:Can we rename Silicon Valley? by slew · · Score: 1

    [Off topic] When I see the name Silicon Valley, I can't help but think the area does anything but manufacture Silicon Hardware. Now its the land of software and venture capitalists and start-ups. More of a vultures den.

    Seems like the majority of "silicon" or hardware vendors moved to Texas.

    They can rename Silicon valley when they finally clean up all the toxic dumping sites they left behind...

  19. Re:tech innovation causes chronic ills? by js290 · · Score: 1

    I suspect infant mortality factors into the average life expectancy calculation?

    --
    "Tempers are wearing thin. Let's just hope some robot doesn't kill everybody." --Bender
  20. Re:Can we rename Silicon Valley? by HiThere · · Score: 1

    Most of them moved to Japan or Taiwan or South Korea. Texas got the residue. (But I hear that many of the early movers moved on to China, and a few of those have started looking at Indonesia.)

    --

    I think we've pushed this "anyone can grow up to be president" thing too far.
  21. Snake oil actually works... by mha · · Score: 1

    Just found this today on HN: "Snake oil can be beneficial for arthritis and other conditions (2007)"

    https://news.ycombinator.com/i...

    The article being discussed is

    https://www.scientificamerican...

    > Snake Oil Salesmen Were on to Something
    > Snake oil really is a cure for what ails you, if that happens to be arthritis, heart disease or maybe even depression

  22. Snake oil actually works... by mha · · Score: 1

    ...for arthritis, heart disease or maybe even depression:

    https://www.scientificamerican...

    > Snake Oil Salesmen Were on to Something
    > Snake oil really is a cure for what ails you, if that happens to be arthritis, heart disease or maybe even depression

  23. Re:Never know when it ends by russotto · · Score: 1

    IF/When it happens, the US will cease to be the innovation leader as all the smart people will flee the medical industry.

    When that happens, it's the end of medical innovation full stop. Who else is going to do it? Europe? Africa? The Middle East? Russia or China?

  24. Most of those jobs would become government jobs by rsilvergun · · Score: 1

    It's single _payer_. We're not nationalizing care and it's not a government take over of health care (whatever Rush & Hannity tells ya). We're just changing who pays the bills. The bills still get paid. Those jobs go from being crap jobs with shit benefits and no job security to government jobs with all the benefits and protections therein.

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