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Spread of Breast Cancer Linked To Compound In Asparagus and Other Foods (theguardian.com)

Asparagus and other foods like potatoes, nuts, legumes and soy contain a compound known as asparagine, which researchers believe helps drive the spread of breast cancer to other organs. "When scientists reduced asparagine in animals with breast cancer, they found that the number of secondary tumors in other tissues fell dramatically," The Guardian reports. "The spread of malignant cells, often to the bones, lungs and brain, is the main cause of death among patients who are diagnosed with breast cancer." From the report: Asparagine is an amino acid that is made naturally in the body as a building block for proteins. But it is also found in the diet, and in high levels in certain meats, vegetables and dairy products. The international team of cancer specialists from Britain, the U.S., and Canada studied mice with an aggressive form of breast cancer. The mice develop secondary tumors in a matter of weeks and tend to die from the disease within months. Writing in the journal Nature, the researchers describe how they reduced the ability of breast cancer to spread in the animals by blocking asparagine with a drug called L-asparaginase. To a lesser extent, by putting the animals on a low-asparagine diet worked too. Inspired by the results, the scientists examined records from human cancers and found that breast tumors that churned out the most asparagine were most likely to spread, leading patients to die sooner. The same was seen in cancers of the head, neck and kidney.

29 of 74 comments (clear)

  1. "How Does the Media Get Something So Wrong" by Anonymous Coward · · Score: 5, Informative

    Straight to the blowing stuff out of proportion department...
    https://www.acsh.org/news/2018/02/08/no-asparagus-wont-give-you-cancer-12546

    1. Re:"How Does the Media Get Something So Wrong" by ReeceTarbert · · Score: 1

      Where are the mod points when I need them? ;-)

      Please, mod +1 informative!

      RT.

    2. Re:"How Does the Media Get Something So Wrong" by Tx · · Score: 4, Insightful

      Welcome to the clickbait age. "Widely used leukemia drug may help slow spread of other cancers also" might get some clicks in bio-medical circles, but it wouldn't draw the clicks from the wider public. But make it sound like a compound in common foods has been discovered to be linked to spreading cancer, and watch the ad impressions roll in. Even relatively respectable publications just can't resist that kind of thing these days.

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      Oh no... it's the future.
    3. Re:"How Does the Media Get Something So Wrong" by Anonymous Coward · · Score: 2, Informative

      The acsh headline is more crap than the guardian article, which doesn't say it causes cancer ... it says it causes the spread of existing breast cancer into other tissues. which was already known for the most part.

    4. Re:"How Does the Media Get Something So Wrong" by KozmoStevnNaut · · Score: 3

      If there was a "+6, Correcting severe misinformation in the headline and summary" mod point I could give you, I would.

      Thank you for giving us the facts.

      --
      Eat the rich.
    5. Re:"How Does the Media Get Something So Wrong" by dgatwood · · Score: 1

      If your body produced sugar by photosynthesis, you'd have a point.

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  2. I wish this had been discovered... by hyades1 · · Score: 1

    ...three years ago.

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  3. Aspergers causes cancer by skovnymfe · · Score: 1, Troll

    I knew it.

  4. Re: potatoes and soy is the world's #1 food by hyades1 · · Score: 4, Funny

    "The Dutch only eat potatoes...So what does the world need to eat to avoid this issue?"

    The Dutch

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  5. Re:So... by GrumpySteen · · Score: 5, Informative

    It was approved for use by the FDA in 1978 and is considered one of the safer chemotherapy drugs, so it is definitely a viable drug for cancer patients.

    The study isn't about discovering a new drug. It's is about gaining a better understanding what the existing drug does so that we can use it more effectively.

  6. Re:Knew it! by haruchai · · Score: 1, Offtopic

    I knew that Asparagus was the devil's vegetable, not only is it disgusting, it makes your pee smell bad too. Any "food" that does this simply couldn't be healthy.
    Oh but we're f*cked.
    "Asparagine is present in plants proteins in large amount.
    Animal sources: dairy, whey, beef, poultry, eggs, fish, lactalbumin, seafood.
    Plant sources: asparagus, potatoes, legumes, nuts, seeds, soy, whole grains. Asparagine is found in potatoes so eating French fries will give you asparagine along with starch. It is also found on roasted coffee."

    In other words, EVERYTHING causes cancer

    --
    Pain is merely failure leaving the body
  7. Many common foods by HalAtWork · · Score: 2

    Nuts, whole grains, seeds, eggs, soy, potatoes, legumes, poultry, dairy, beef, seafood.

    That's a lot to avoid. I wonder which are highest in asparagine, then perhaps having less of the highest ranking ones would be a start.

    1. Re:Many common foods by turp182 · · Score: 1

      Not as much to avoid as common noises, which might cause heart disease...

      http://abcnews.go.com/Health/e...

      Of course the world death rate is still at 100%:
      https://www.theonion.com/world...

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  8. Research : this just in by houghi · · Score: 2

    This just came in :
    Research causes cancer in rats. More news at 11:00.

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  9. Re:But Asparagus is still nasty! by XxtraLarGe · · Score: 1, Informative

    I love asparagus.PictSweet Steamables are one of my go-to veggies for the week. It's still nice & firm after it's been microwaved. The only thing I don't like about it is the nasty side effect.

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  10. Curse you Carbon, Oxygen and Hydrogen! by jellomizer · · Score: 3, Insightful

    These three elements seem to be the root cause of nearly every illness. Yet they use them all the time in our food, and our body has a large concentration of this in our systems ready to kill us at any time.

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  11. Kids Agree! by sycodon · · Score: 2

    Vegetables, especially Asparagus, will Kill You!!

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  12. Over simplified by DaMattster · · Score: 1

    I am not surprised that there may be some compounds in foods that can cause cancer. But what we do not know is how they do and with what other compounds they must mix with in order to potentially cause cancer. If you eat a crappy diet and take some supplements that are purported to prevent cancer, you can still end up getting cancer because the compounds that are supposed to fight cancer react totally differently when mixed with the crappy foods.

  13. Wait just a minute by kilodelta · · Score: 1

    So meats, vegetables and dairy products - all they left out is fruits. Sort of like what I say about vegans - if they pull the moral superiority card out I mention that trees and plants also communicate, reproduce etc. They're just as alive as say a chicken or us. So eat air.

  14. Re:So... by hcs_$reboot · · Score: 4, Funny

    So... stop eating asparagus, potatoes, nuts, legumes. Focus on processed meat, butter and sweets to keep the cancer away.

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  15. Something a little more promising is... by Maelwryth · · Score: 1

    This.

    Injecting minute amounts of two immune-stimulating agents directly into solid tumors in mice can eliminate all traces of cancer in the animals, including distant, untreated metastases, according to a study by researchers at the Stanford University School of Medicine.

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    1. Re:Something a little more promising is... by Maelwryth · · Score: 1
      --
      I reserve the write to mangle english.
  16. Ah, so that's pee cancer... by kimgkimg · · Score: 1

    I knew something smelled funny.

  17. Re:So... by Hal_Porter · · Score: 4, Funny

    You fancy a kale smoothie for lunch. Also for dinner.

    This post sponsored by the Kale Marketing Board.

    --
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  18. Re:Soy by Hal_Porter · · Score: 1

    Because (((they))) want you to eat soy to lower your testosterone levels. Stick to Super Male Vitality, stay woke.

    --
    echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
  19. Re:So... by Anonymous Coward · · Score: 1

    Kale is NEVER safe to eat.

  20. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  21. Re:But Asparagus is still nasty! by burningcpu · · Score: 1

    This is the same for men. I run from a toilet after I've pissed asparagus effluent. Stank!

  22. Re:So... by grep+-v+'.*'+* · · Score: 1

    I've got cancer (currently being treated, level 2 out of 4) and that's exactly what I'm doing. I'm blaming asparagus for my condition, and consider myself LUCKY that I haven't accidentally touched more and made myself even worse.

    Ok, this is broccoli, but you get the idea.

    --
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