Identical Twins Test 5 DNA Ancestry Kits, Get Different Results On Each (www.cbc.ca)
Freshly Exhumed writes: Uh-oh, something is not right with the results of most popular DNA ancestry kits, as a pair of identical twins have found. Charlsie Agro and her twin sister, Carly, bought home kits from AncestryDNA, MyHeritage, 23andMe, FamilyTreeDNA and Living DNA, and mailed samples of their DNA to each company for analysis. Despite having virtually identical DNA, the twins did not receive matching results from any of the companies. "The fact that they present different results for you and your sister, I find very mystifying," said Dr. Mark Gerstein, a computational biologist at Yale University. Gerstein's team analyzed the results, and he asserts that any results the Agro twins received from the same DNA testing company should have been identical. The raw data collected from both sisters' DNA is nearly exactly the same. "It's shockingly similar," he said.
Now stop stealing my clothes and trying to trick my girlfriend, asshole!
SJW: Someone who has run out of real oppression, and has to fake it.
Clearly, one of them was switched at birth. With their triplet.
Corruption is convincing someone that the selfless ideal is the same as their selfish ideal.
They should be identical. Will not be due to normal error. Or may not be even close due to incompetence.
is making the random numbers come out the same when they detect twins submitting dna.
They're IDENTICAL twins, right? Why would their DNA be "virtually" the same? Why would there be ANY level of shock with that? ELI5 please.
Let's have the Hensel twins repeat this experiment. Hilarity ensues.
What is the point of the identical twins (other than adding click-bait value)? Why not submit two samples from the same person under different names?
None of them can see the clouds; The polished wings don't care.
Somewhat begs the question of the accuracy of said tests doesn't it ?
Don't panic, TFA said the raw data was "statistically identical". You can still use tools like SNPedia and Promethease to explore your own raw data.
...are the professional forensic kits that law enforcement use as bad as this?
"But remember, most lynch mobs aren't this nice." (H.Simpson)
-- Joe
Some people don't realize that none of these services sequence the full genome. They sequence a collection of different sites as best they can (from the spit that you send them in a tube). Some sites will be sequenced really well and some not at all; it is the random nature of the system. What happens if twin 1 is sequenced really well at site ABC123 and has some rare mutation there but twin 2 is not sequenced at that site at all? They will assume that twin does not have the mutation - they will sub in "wild type" sequence at that locus as they won't have any thing better to go on - and you'll end up identifying them as being different. Take this many times over thousands of gene loci that they sequence and pretty soon you see how two identical twins can end up looking very different.
If you want to see how similar they really are at the DNA level, you need Whole Genome Sequencing (WGS) or at least you need to know what the coverage was at each locus for each twin. The former still costs thousands in most cases, the latter should be in the raw data (though they would need to convince the companies to release said raw data to them).
Damn_registrars has no butt-hole. Damn_registrars has no use for a butt-hole.
It's entirely possible that twins have different fathers. They should have DNA testing done in person at a well respected facility to know for sure.
about my DNA information, except maybe if it is something medical. Have always looked on these DNA services as useless scams.
;)
I can't help but think of Bill Murry in the movie Stripes! Something about we are Americans, were Mutts. Our forefathers got kicked out of every decent country in Europe. Well something l;ike that it was many years ago.
But that memory has always stayed with me.
On a side note one of these services has a commercial on TV that I think is idiotic. It has this smug woman talking about how she travels all over the world. And people are always asking what her nationality is? And she says, I used to say I was Latino, Now after getting my DNA checked I realize I am everything!
I sit back in my chair and shake my head. They asked her what her nationality is! Not what her ethnicity is! Seems to me a non idiot would say I'm American. But hey what do I know.
Just my 2 cents
that's nice, dear. now take your medicine like your doctor told you and go back to bed.
"But remember, most lynch mobs aren't this nice." (H.Simpson)
-- Joe
Did their insurance companies store all 10 results to deny both of them cover in the future?
So did you take Bob Wilson's "Illuminatus!" as a history?
I think we've pushed this "anyone can grow up to be president" thing too far.
Spying is big business. For example, spying is Google's main theme for which services to keep and which to do away with. Perhaps spying is driving these ancestry services as well. We already know these ancestry services share client data with police (1, 2, 3). Perhaps this data sharing is listed in the terms of service, but either way the sharing helps authorities augment their database and helps them perform more surveillance on ordinary citizens (most citizens don't commit crimes and therefore should not face such treatment; I'm not convinced those who commit crimes deserve this treatment but the vast majority of the public absolutely don't).
Digital Citizen
After she dies.
https://en.wikipedia.org/wiki/...
"FamilySearch is a genealogy organization operated by The Church of Jesus Christ of Latter-day Saints (also known as the LDS Church). ... ...
The resource is maintained to support the process of obtaining names and other genealogical information so that Latter-day Saints can perform temple ordinances for their kindred dead.[3]
In February 2014, FamilySearch announced partnerships with Ancestry.com, findmypast and MyHeritage, which includes sharing massive amounts of their databases with those companies. They also have a standing relationship with BillionGraves, in which the photographed and indexed images of graves are both searchable on FamilySearch and are linked to individuals in the family tree.[6]"
https://en.wikipedia.org/wiki/......
"The LDS Church teaches that deceased persons who have not accepted, or had the opportunity to accept, the gospel of Christ in this life will have such opportunity in the afterlife. The belief is that as all must follow Jesus Christ, they must also receive all the ordinances that a living person is expected to receive, including baptism. For this reason, members of the LDS Church are encouraged to research their genealogy. This research is then used as the basis for church performing temple ordinances for as many deceased persons as possible. As a part of these efforts, Mormons have performed temple ordinances on behalf of a number of high-profile people, including the Founding Fathers of the United States,[47][48][49] U.S. Presidents,[47] Pope John Paul II,[50] John Wesley,[47] Christopher Columbus,[47] Adolf Hitler,[51] Joan of Arc,[51] Genghis Khan,[51] Joseph Stalin,[51] and Gautama Buddha.[51] ...
In February 2012, the issue re-emerged after it was found that the parents of Holocaust survivor and Jewish rights advocate Simon Wiesenthal were added to the genealogical database.[74] Shortly afterward, news stories announced that Anne Frank had been baptized by proxy for the ninth time, at the Santo Domingo Dominican Republic Temple.[75]"
Mormons are playing the long game of baptizing everyone ever straight into their "free planets for everygod" heaven.
If that means buying up banks of genetic data one by one... so be it.
Mit der Dummheit kämpfen Götter selbst vergebens
Hey, just just bought two nearly identical barometers from crap-o-mart for $5 each. I put them next to each other in the same room. Imagine my horror when I noticed that their respective readings differ by as much as 10%.
Oh, BTW, 23andme terms of service are clear, at least.
"The laboratory may not be able to process your sample, and the laboratory process may result in errors ... Even for processing that meets our high standards, a small, unknown fraction of the data generated during the laboratory process may be un-interpretable or incorrect (referred to as "Errors" ..."
Inexpensive direct to consumer DNA testing companies to not provide nor claim to provide results with statistically insignificant error rates. Don't we all already know this?
The results are good enough to do fun things like find previously unknown relatives. To date, I've found three second cousins using 23andme. My ancestry information was likely not perfect but was accurate enough for intended purposes.
The article makes much of one difference: one service shows Eastern European heritage, while the other Balkans.
But there is not a clear definition of "Eastern Europe" and it may include the Balkans, so this may be not more than a difference in semantics.
The real "Libtards" are the Libertarians!
Now, get off my lawn you damn kids ... at least the ones that I can prove are not mine!
Interesting. I thought scenarios involving siblings with mismatched DNA was called the Milk-man Paradox. :)
I suspect if a reporter did submit samples under different names, a court would side with the press against their terms of service. Eventually.
But by using identical twins, you sidesteps the possibility of wasting time, effort, and money because your report has been tied up by a gag order while a court mulls over what to do.
Slashdot has persisted, because of the (IMHO) amazing moderation on Slashdot had implemented from the beginning.
True that. I can't talk for others, but on quite an occasion i upvote comments i disagree with but are well argumented and worth considering a thought, and downvote comments i might agree with due to offensive language.
A glitch a day keeps the bugs away.
I'm reminded of the opposite story: someone forgets their password to the DNA site, and (instead of resetting the password) creates another account, sends in new DNA... and later calls their kid saying that it's incredible, wonderful, this DNA site has found that I have an identical twin somewhere!
While I agree that we should upvote well argued comments in spite of disagreeing with them, I may disagree with you on the downvoting of offensive language post. IMO, for something to be offensive, there must also be intent to offend...if that's what you're point is, then we're in agreement. However, far too often, we see people taking offense to wording such as Washington Redskins. If you find that offensive, it's on you, not the source of the words.
Just another day in Paradise
Sad that Mark chimed in.
Vast majority of differences are in one point, which is as we all know, naturally expected error if the number of digits presented is constructed correctly, to reflect that natural error.
As for larger deviations it came from lack of statistics. They probably have a randomizer to present the data with low statistics so the distribution of results represents the fact that statistics is low. I would not do that, but it's a legit technic.
My experience was laughable with one of the companies. They traced me back to Spain, to which I have absolutely no relation.
I did not make a big deal out of it realizing that the culture I am from is very small and not well represented in reference data of these companies.
In short:
- This is a natural variation of results. Move along, nothing to see here.
- If you have trusted to the point this data before this, you are a fool
I do not believe in karma. "Funny"=-6. Do good and forbid evil. Yours, Oft-Offtopic Flamebaiting Troll.
"She claimed to be part Cherokee"
False. She claimed that her family claimed that she was part Cherokee. Nice try though
"You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
Link some evidence or go away.
Just another day in Paradise
To be fair, same company assigned very similar results to both twins. Non-identical results because of error margin in testing methodology, but similar enough for error to be negligible.
The problem is more about differential between companies, who clearly define "where you came from" in a very arbitrary fashion, making results highly questionable at best, and utterly worthless at worst.
That and the fact that there's an error margin within the test itself. If I remember correctly, replication of the sample for testing in the less rigorous (read: cheaper) methods is imperfect, leading to small variations.
No, DNA companies are run by people of a furtherance of backgrounds. There is no "most", other than most are run by people still living.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
Ummm, most of these services don't offer ancestral breakdowns unless you buy that optional extra. Nobody believes the ancestral breakdowns, they've been discussed to death, they're a stupid idea based on tiny sample sizes and meaningless correlations.
Nobody looks at those. The companies that give a breakdown should be informed that they should back off or go help populate Mars. Same with those who worship such results. They damage severely the credibility of the valuable data.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
What differed was ancestral breakdown, which is a flawed methodology based on correlating patterns with other patterns in a pseudoscientific way.
The results were the same.
Ancestral breakdown is not a result, it is a fable. You cannot determine ancestry by country or region through DNA, with the data set that currently exists, and it may not be possible at all. There's no reason to think it is.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
Actually, being a "satan worshiping jew" sounds pretty cool.
Just cruising through this digital world at 33 1/3 rpm...
I can't talk for others, but on quite an occasion i upvote comments i disagree with but are well argumented and worth considering a thought, and downvote comments i might agree with due to offensive language.
And here I thought I was the only one who did that.
Yes, I may upvote a comment I disagree with if it's a well-formed argument or raises a valid point. And I may downvote comments that are technically correct but are written with an abusive form or tone.
Just cruising through this digital world at 33 1/3 rpm...
How many different companies did Elizabeth Warren submit her DNA to before she could claim to be a Native American?
FWIW, my daughter did only one, and it showed a sliver of Native American, which was most definitely an error...anticipating the jokers here to comment. Her other half is 100% Korean, and I have no Native American lineage. Our guess is that there's some commonality between Koreans and Native Americans that's too close to call for them.
Just another day in Paradise
GP is greatly exaggerating (probably because he's a racist), but there was an interview where employees at these companies admitted to trolling racists by fudging the results with trace heritage to the ethnicity the racist didn't like, which is hilarious, awesome, and valuable:
http://www.cracked.com/persona...
"When information is power, privacy is freedom" - Jah-Wren Ryel
Yup, just like any large company, there are always some assholes. IMO it would be "hilarious, awesome, and valuable" if they had done it on their own time. Not so much when they implicate the business they work for.
Just another day in Paradise
I met him for the first time yesterday. It said we share 23.5% of our genes (not 25%) Other evidence corroborates it. It's 100% certain. Maybe this is an issue; maybe it isn't, but this "test" seems superficial to me.
How about a moderation of -1 pedantic.
The taxonomical moderation of Slashdot allow that. Something can be Funny, Informative or Interesting even if I don't agree with it.
Something can be Informative even if it offends me. Way too many people can't separate the content from how it makes them feel
Sleep: the greatest cause of genetic mutation. Only on /.
Both my twin sisters submitted their DNA on Ancestry, and on the matches page, it said of the other twin - this person is either you, or an identical twin.