I am using Fedora from the start and I like it very much, but I don't think its philosophy is suitable for a "national" distribution.
Fedora is created for testing, not for everyday usage for normal people (not neerds). I think even using Fedora qualify you as a nerd. OK, it gets even worse if you are using alpha's.
Using Fedora will cripple their productivity and they will start to hate Linux.
If they want to use Linux for serious stuff, like "national distribution", then they should chose another distro.
It is not an easy task ether. I have been running a forum for two or three years (20-30 posts per day), and it has been a lot of work and a lot of problems I wouldn't think of.
What has finally made me quit was a lack of time and problems with spam... It was getting worse and worse, they find a way to sneak in and they post those 40 penis enlargement adds in it...
"And the recommended alternates - Thunderbird & Lightening - don't exactly compare favourably to Exchange + Outlook."
I use Evolution on Fedora 10 and I love it. I am using my email with an IMAP connection, works like breeze and I love it. There are really good guys taking care of the server with my email account on it, I am using it for 15 years now;)
And no downtime or problems for me in that period !!! And I am using email for professional needs. Off course, they didn't pay a penny for that server and it serves in a fantastic way for so long.
And if something wrong would happen (but it didn't in 15 years I am using it), then I would just call those guys and ask them to go through the logs...
For the Exchange functionality.... you have plugins for Lotus Notes and Exchange on Evolution... but there is no real need for that. There are also open source solutions for Exchange out there... and getting better and better with time...
"Governments differ from schools in a few important ways"
But the one, very important one, stays the same:
One the long run, proprietary solutions cost more. If this is not an issue for you, then OK. Taxpayers are stupid and they can be fooled, but If I would be a dean, I would like my IT administrators to do some more usefull stuff than install antivirus software on computers and even pay them for that software so they can do it their work time ???
What you said, aren't actually so serious drawback issues. They seem more cosmetic to me. You can accomplish all your professional tasks, if I understand it right. You just want it to be fancy. But you have to pay for fancy, a lot of money actually. And this money is drawn away from students in university...
What is you choice... fancy gui or more money for the research ? My choice is clear and your should probably also be as clear, if you would be paying it from your pocket.
And OO is getting better and better. I can say, I had some problems using in those 1.x version days. But now, I can't really complain of anything, that would hinder my productivity. Interesting, there are more and more stuff in OO, that don't exist in M$O.
You must be joking. I wouldn't use G-apps including mail for my professional needs... there are security problems involved and I need serious support for my work. I am also working with databases, I want to encrypt my mail. I can't get these on Google for free.
OpenOffice does everything I need for my work.
Can you tell me please, what do you personally miss in OpenOffice, so you have to use M$ Office ?
"Trying a global migration to OSS, or anything else, is doomed to failure. "
Eeee, wrong...
Did you actually read Declaration of independace you are replaying too ? You should.. It can be done and it has been done and in 2011 Munich will run 80% Linux on desktop.
You should know how to do it... it is doomed to failure if you are doing it wrong !
I am not confusing nothing. I said, that we don't know how to do it today. But if we want to change Umbilical cord cells to beta cells, we also have to learn the same step. When we learn those steps, then it will be the same if we use Umbilical cord cells or reverted somatic cells.
There are some more convenient cells than alpha cells to convert them to beta cells. Some have been mentioning molar tooth cells or something and some others.
Some patients with extreme insulin resistance (impaired ability of the body's cells to allow glucose in the blood to pass through the cell walls) need years to develop hyperglycaemia and some also never develop hyperglycaemia despite very severe insulin resistance...
As you also said, it could be a very good one. You would visit a cell factory every ten years and they would implant new cells under your forearm skin. No more insulin, no more pills, no more blood checking 7 time a day, no more hypoglicemias, no more kidney failure, etc...
This shouldn't be a problem for type II diabetes, that represents large majority of cases of diabetes in the world. I agree with you that in type II diabetes, insulin resistance is the one to blame. But the blood sugar values go high only after about 50% of beta cells are destroyed because of "burnout" after years of hyperinsulinemia. In those patients, you could theoretically recover insulin production with implantation of beta cells, and those people wouldn't need insulin any more. This would be a big breakthrough, if it would be possible...
In type I diabetes, researchers are working on a special "cage", that could protect implanted cells from autoimmune response, while preserving the nutrition and other staff for those cells.
In May 2006, The World Marrow Donor Association (WMDA) Policy Statement for the Utility of Autologous or Family Cord Blood Unit Storage stated that:
1. The use of autologous cord blood cells for the treatment of childhood leukemia is contra-indicated because pre-leukemic cells are present at birth. Autologous cord blood carries the same genetic defects as the donor and should not be used to treat genetic diseases.
"Physicians should be aware of the unsubstantiated claims of private cord blood banks made to future parents that promise to insure infants or family members against serious illnesses in the future by use of the stem cells contained in cord blood;"
I want to say, that we will have a very powerful weapon for fighting diseases, when we will be able to use the full potential of those stem cells, which is now not fully available. When it will be, then it will be the same if you use umbilical or somatic cells... it will not matter....
Slashdot Mirror
I am using Fedora from the start and I like it very much, but I don't think its philosophy is suitable for a "national" distribution.
Fedora is created for testing, not for everyday usage for normal people (not neerds). I think even using Fedora qualify you as a nerd. OK, it gets even worse if you are using alpha's.
Using Fedora will cripple their productivity and they will start to hate Linux.
If they want to use Linux for serious stuff, like "national distribution", then they should chose another distro.
It is not an easy task ether. I have been running a forum for two or three years (20-30 posts per day), and it has been a lot of work and a lot of problems I wouldn't think of.
What has finally made me quit was a lack of time and problems with spam ... It was getting worse and worse, they find a way to sneak in and they post those 40 penis enlargement adds in it ...
How much does a sub 1k Slashdot UID cost on a free market ?
Maybe I can buy myself a good UID and the girls will go crazy on me.
"And the recommended alternates - Thunderbird & Lightening - don't exactly compare favourably to Exchange + Outlook."
I use Evolution on Fedora 10 and I love it. I am using my email with an IMAP connection, works like breeze and I love it. There are really good guys taking care of the server with my email account on it, I am using it for 15 years now ;)
And no downtime or problems for me in that period !!! And I am using email for professional needs. Off course, they didn't pay a penny for that server and it serves in a fantastic way for so long.
And if something wrong would happen (but it didn't in 15 years I am using it), then I would just call those guys and ask them to go through the logs ...
For the Exchange functionality .... you have plugins for Lotus Notes and Exchange on Evolution ... but there is no real need for that. There are also open source solutions for Exchange out there ... and getting better and better with time ...
"Governments differ from schools in a few important ways"
But the one, very important one, stays the same:
One the long run, proprietary solutions cost more. If this is not an issue for you, then OK. Taxpayers are stupid and they can be fooled, but If I would be a dean, I would like my IT administrators to do some more usefull stuff than install antivirus software on computers and even pay them for that software so they can do it their work time ???
What you said, aren't actually so serious drawback issues. They seem more cosmetic to me. You can accomplish all your professional tasks, if I understand it right. You just want it to be fancy. But you have to pay for fancy, a lot of money actually. And this money is drawn away from students in university ...
What is you choice ... fancy gui or more money for the research ? My choice is clear and your should probably also be as clear, if you would be paying it from your pocket.
And OO is getting better and better. I can say, I had some problems using in those 1.x version days. But now, I can't really complain of anything, that would hinder my productivity. Interesting, there are more and more stuff in OO, that don't exist in M$O.
You have to know how to do it. Germans did it right, so they succeeded.
It isn't impossible to migrate. It costs money, but on the long run you win. The potential cost reduction is huge on the long run.
And the most important reason to migrate is very well described in this document:
http://osor.eu/case_studies/declaration-of-independence-the-limux-project-in-munich
The reason is : "the main motive is the desire for strategic independence from software suppliers."
You must be joking. I wouldn't use G-apps including mail for my professional needs ... there are security problems involved and I need serious support for my work. I am also working with databases, I want to encrypt my mail. I can't get these on Google for free.
OpenOffice does everything I need for my work.
Can you tell me please, what do you personally miss in OpenOffice, so you have to use M$ Office ?
"Trying a global migration to OSS, or anything else, is doomed to failure. "
Eeee, wrong ...
Did you actually read Declaration of independace you are replaying too ? You should .. It can be done and it has been done and in 2011 Munich will run 80% Linux on desktop.
You should know how to do it ... it is doomed to failure if you are doing it wrong !
Bes
http://osor.eu/case_studies/declaration-of-independence-the-limux-project-in-munich
"i win!"
An award for the greatest idiot of all times ...
http://www.spiegel.de/wissenschaft/mensch/0,1518,605606,00.html
I am not confusing nothing. I said, that we don't know how to do it today. But if we want to change Umbilical cord cells to beta cells, we also have to learn the same step. When we learn those steps, then it will be the same if we use Umbilical cord cells or reverted somatic cells.
There are some more convenient cells than alpha cells to convert them to beta cells. Some have been mentioning molar tooth cells or something and some others.
It is a pre-slashdot effect.
It is true, it costs only 10 bugs, but you have to stay subscribed for something for next 47 years ...
"Unfortunately, in both types, replacement of beta cells is only a treatment of the disease and not a cure."
I agree totally with you now.
It's not actually a cure, but it could be a very good treatment ...
I don't agree with you :
http://science.slashdot.org/comments.pl?sid=1106541&cid=26642625 ... the blood sugar values in type II diabetes go high only after about 50% of beta cells are destroyed because of "burnout" after years of hyperinsulinemia ...
Some patients with extreme insulin resistance (impaired ability of the body's cells to allow glucose in the blood to pass through the cell walls) need years to develop hyperglycaemia and some also never develop hyperglycaemia despite very severe insulin resistance ...
I want to know, what do you think about that fact:
http://science.slashdot.org/comments.pl?sid=1106541&cid=26639505
I really want to know your opinion about that article, because you are an expert in this field ...
"it's a treatment."
As you also said, it could be a very good one. You would visit a cell factory every ten years and they would implant new cells under your forearm skin. No more insulin, no more pills, no more blood checking 7 time a day, no more hypoglicemias, no more kidney failure, etc ...
For me, this is almost like curing the disease.
Maybe they could clone Odie, so Garfield would have two or three of them ...
The story with leukemia is not simple as you suggest:
http://slashdot.org/comments.pl?sid=1106541&cid=26640663
It could be used with adults, that "acquired" leukemia because of other reasons .. radiation, chronic toxins exposure ...
I am not really an expert in that field ...
This shouldn't be a problem for type II diabetes, that represents large majority of cases of diabetes in the world. I agree with you that in type II diabetes, insulin resistance is the one to blame. But the blood sugar values go high only after about 50% of beta cells are destroyed because of "burnout" after years of hyperinsulinemia. In those patients, you could theoretically recover insulin production with implantation of beta cells, and those people wouldn't need insulin any more. This would be a big breakthrough, if it would be possible ...
This article spits on my previous claims, but I am still somehow sure, that we could somehow down-regulate normal cells to act the same:
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17274951&ordinalpos=22&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
In type I diabetes, researchers are working on a special "cage", that could protect implanted cells from autoimmune response, while preserving the nutrition and other staff for those cells.
http://en.wikipedia.org/wiki/Cord_blood
In May 2006, The World Marrow Donor Association (WMDA) Policy Statement for the Utility of Autologous or Family Cord Blood Unit Storage stated that:
1. The use of autologous cord blood cells for the treatment of childhood leukemia is contra-indicated because pre-leukemic cells are present at birth. Autologous cord blood carries the same genetic defects as the donor and should not be used to treat genetic diseases.
I am suggesting an investment in these:
http://en.wikipedia.org/wiki/Prayer_wheel
"if they can't do it with somatic cell, then they can't do it with an umbilical" doesn't hold much water.
http://en.wikipedia.org/wiki/Cord_blood#Cord_blood_harvesting .... The American Academy of Pediatrics 2007 Policy Statement on Cord Blood Banking states that:
"Physicians should be aware of the unsubstantiated claims of private cord blood banks made to future parents that promise to insure infants or family members against serious illnesses in the future by use of the stem cells contained in cord blood;"
I want to say, that we will have a very powerful weapon for fighting diseases, when we will be able to use the full potential of those stem cells, which is now not fully available. When it will be, then it will be the same if you use umbilical or somatic cells ... it will not matter ....