While you are certainly correct that pot is incredibly unlikely to be helpful here you veer into some pretty heavy scare tactics that dont have a lot of truth to them.
"". In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances [americanad...enters.org]"
For starters, medical pot is legal in more states than not so why are we assuming the purchase would be illegal? After that, a small amount of critical thinking quickly brings up the question, why would some one selling weed spend money lacing their product and not tell the person buying? Your own link even states there's no data on the subject.
"And stop claiming that marijuana is harmless. I see too many people land in our ED as a result of this type of self-medication."
While, much like drinking, there are those who will do truely stupid things while high pot is far safer than every day activities like sober driving or manual labor professions.
While you are certainly correct that pot is incredibly unlikely to be helpful here you veer into some pretty heavy scare tactics that dont have a lot of truth to them.
I'm sorry, what scare tactics did I refer to? I have not referred to any well publicized and likely misleading sources used by the war on drugs - I have not referenced the usual claims of lowering IQ or as a gateway drug even though it is reported in a peer reviewed journal. I specfically avoided such sources because I knew someone would attempt to discredit them. What I have given you is clinical experience (19 years now) of issues that I have encountered with actual patients that I have treated. I have had people so strung out on drugs that they failed to recognize a decline in their health that made their condition worse. I have stuporous individuals who have serious medical derangements that we could not determine from their history (they weren't able to talk or were exhibiting paranoia) or from physical exam (they were so out of it I couldn't get they to react to any exam or they refused to cooperate with the exam) Related reference here. It is still illegal to drive after using marijuana in Colorado and California.
In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances [americanad...enters.org]"
For starters, medical pot is legal in more states than not so why are we assuming the purchase would be illegal? After that, a small amount of critical thinking quickly brings up the question, why would some one selling weed spend money lacing their product and not tell the person buying? Your own link even states there's no data on the subject.
You might have missed the news on CD awhile back, ask your doctor if he/she knows what causes Crohn['s]
This is a very interesting article and they may be on to something, but it is far from the first time Crohn’s disease has been attributed to microbes. They make a good argument, but I don't think that this closes the case yet. They specifically note that this is for "Familial Crohn’s Disease" and not all cases are familial. This was also a study that only looked a 9 family, with an n of 20, so this is not a very large study, and these are likely geographically co-located (but they did not give a lot of data on that). I'll avoid a long history of the disease and just place the gentle reminder that correlation is not causation (and in medicine the level of evidence for proof is often much higher than in other sciences). A lot more research needs to go into this - but investigating the complex relations in the gut biome is probably going to yield some very good insights.
So I'll continue with my standard answer for Crohn's that "we still don't know for sure" - but we're getting closer.
This is not a joke. Try smoking (or vaping, or eating) some marijuana. It tends to relax internal muscles and may help you pass it. At worst, it's a cheap, harmless, fun thing to try before going in for a more complicated, potentially needless procedure.
This is not a joke, this is some of the worst advice. Please stop posting uninformed advice that is more harmful than helpful.
Muscle relaxants (of which marijuana is a poor one) are not useful here and are actually contraindicated. This capsule is not hung up on a sphincter, it is likely caught in a stricture and inhibition of peristalsis is not going to help and may make matters worse.
In addition, by consuming marijuana and getting "high" he or she may miss changes in their condition that indicate that they need to get to the hospital emergently (e.g. abdominal pain indicative of intestinal rupture). If they decide to take themselves to the ED, driving while impaired is illegal in all states not to mention just plain dangerous. Once there, again, being under the influence of a psychoactive drugs they may not give a thorough medical history, or it may alter the physical exam findings, possibly leading to a misdiagnosis (even with EMRs - I have seen this happen). Marijuana may also interact with other more useful medications that need to be given leading to further complications. In addition, diagnostic tests may be delayed as they won't be able to properly consent after consuming an substance that alters cognition. In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances
In short, please don't self-medicate. This is especially true when you have a complex medical condition. Leave the medical advice to someone who is trained and qualified.
And stop claiming that marijuana is harmless. I see too many people land in our ED as a result of this type of self-medication.
Maybe you can use some strong rare-earth magnets to help it along?
This is highly unlikely to work. The problem? You think of the intestine as a linear tube from mouth to colon (then anus), but in reality there are many twists and turns in the intestine (which happens in real time - aka peristalsis). So for any placement of the magnet, you are just as likely to hang it up as to move it along - so doing this yourself won't help - and may actually be harmful if the magnet is strong enough and left in one area too long. That being said....someone has already thought of this. But if you look at the article, it looks like a pretty elaborate setup that likely only exists as a handful centers in the world as this would need to be done in real-time with imaging (looks like a mini CT scanner).
After 12 weeks, the likelihood of this passing on its own is virtually nil, so it will need some help. Double balloon enteroscopy (aka push enteroscopy) can be used if not too far in, and is performed at most university/academic medical centers. Other medical options are descried here. A more aggressive, but not maximally invasive choice would be to bring a surgeon into the mix to do a combination of double balloon enteroscopy and a laparoscopy or just plain old laparoscopy.
The Hitchhiker’s Guide to the Galaxy defines the Federal Communications Commission as “a bunch of mindless jerks who’ll be the first against the wall when the revolution comes,” with a footnote to the effect that the editors would welcome applications from anyone interested in taking over the post of robotics correspondent. Curiously enough, an edition of the Encyclopedia Galactica that had the good fortune to fall through a time warp from a thousand years in the future defined the Federal Communications Commission as “a bunch of mindless jerks who were the first against the wall when the revolution came.”
-- Douglas Adams, The Hitchhiker's Guide to the Galaxy
I would love it if everyone who was interviewed live yelled "Alexa, play 'Never gonna give you up'" randomly while on the air. Mass panic at Amazon. The Rick-rolling to end all Rick-rolling!
First, there have been no reported deaths from this infection as per the article, so how exactly is this deadly? Dangerous, potentially deadly? So, please, lets title these articles responsibly. The remainder of this post is not meant to bash the parent, just to define terms and clarify concepts. My opinion is at the end.
Not a doctor, but there is only a little overlap between antibiotics and antifungal medications.
The term antibiotic covers both anti-bacterial agents (e.g. penicillin) used against bacteria, and anti-fungals (e.g. fluconaole/Diflucan), and technically, they also refer to anti-virals (e.g. aciclovir), but in the most common use, antibiotics refer to antibacterials, and never to antivirals. There are no medications that treat both bacteria (prokaryotes [no nucleus]), fungus (eukaryotes [true nucleus]) simultaneously; yes, bleach (sodium hypochlorite) can destroy both, but internal use is discouraged [and as referenced in the wikipedia article, your body's neutrophils (a type of white blood cell - cells that fight infection) uses hypochlorous acid as an antimicrobial . So.....yes and no. [sorry that kept getting longer and longer]
This stuff is resistant to Diflucan (I'm not trying to spell the generic name correctly right now),
which is often handed out with much less oversight than antibiotics.
Ummm, no. You can get pretty powerful topical antibiotics and topical antifungalsover the counter. Fluconazole is an oral antifungal that still requires a prescription (at least in the US and other "responsible" countries).
Any bio-female could probably get a few doses for a yeast infection without seeing their doctor; calling in and asking is all most require since it is a common ailment.
It is a common ailment, but it is also a true infection that can be cultured and proven, and usually requires treatment. (I don't want you to poo-poo this aliment:-), pretty miserably for those afflicted), and unless there is a well established relationship between physician and patient, an exam is required (and strongly encouraged to rule out other more dangerous diagnoses).
The problem is that many primary care doctors have been told that C. albicans (the common human strain) can not become resistant. I was told the same, only to be corrected by a very indignant Tropical and Infectious Disease specialist who had seen that first line drug become useless in a few cases.
I see fluconazole resistant candida albicans frequently (reported 7% resistance rate), but I work at a tertiary care referral center, so YMMV. Never been under the illusion that it could not become resistant. Every organism (meaning microbial species) given enough time and opportunity can become resistant to just about anything.....The only thing that microbial organisms will never become resistant to is fire, well heat anyways (shout out to the the post below).
But this doesn't mean we need to panic and shut down Madagascar. There are other classes of drugs, like the old standby nystatin, and other families of antifungal medications in the larger azole drug category. This should be treatable if caught early. The danger is that drugs like nystatin can not be absorbed so
How Do I Handle Interruptions At Work? I set the perpetrator ablaze.
When I was writing code, I personally found a strategically placed Claymore mine usually preempts interruptions. Tripwires prevent me from even having to turn around.....
It was one of the ideas pitched to Montgomery Brewster (Richard Pryor) in the movie Brewster's Millions, execpt the guy wanted to tow it from the Arctic.
I think you're on the right track....I have not RTFA, but the synopsis raises some concern about interpreting the conclusion. The data was taken from "General Internal Medicine Division", which are, typically, first line or Primary Care Physicians (PCPs). Often they will make a diagnosis based on their generalized knowledge of a medical problem and often refer them to a sub-specialist (i.e. you have trouble breathing with exertion, you find you need to sleep on multiple pillows, your ankles are swollen and you physical exam and office EKG lead me to refer you to a cardiologist (sub-specialist)) - so yes, the opinion will be different a lot of the time....the generalist can't know everything that a specialist can, but the generalist often triages the problem to someone who does know more.
This could explain the "Among those with updated diagnoses, 66% received a refined or redefined diagnosis, while 21% were diagnosed with something completely different". It'd be interesting to see how they correlated this.
Or more likely there is only so much room to fit people in the Bay Area
Ummm, no. More likely this is another bubble, and we're seeing the first signs its going to pop. How many of these "businesses" that sell "free" products are actually turning a profit? And how many are just waiting to be bought out? Sound familiar? It's the tech version of flipping houses.
I'd also be interested to see how much is contributed back by alum from each major. I'm sure that the liberal arts major who job is to ask "You want fries with that?" will give back a lot less than the engineer pulling 120k while designing chips.
When I see the word Toxins, my bullshit radar activates
I am a physician and yes, my BS meter usually goes up when people who have no understanding of human anatomy, physiology, histology, biochemistry, or pathology start rambling on about toxins. But take it from person who deals with sepsis and critical ill patients on a weekly basis. Bacterial endotoxins are the real deal. There are a significant source of morbidity and mortality in severely ill patients. Also, please realize that this research is in collaboration with Boston Children's Hospital and Harvard's Engineering department.
That being said, I pulled the original article and on first read, it seems to be a potential game-changer. My questions:
1. They liken this to dialysis. Many critically ill patients can not tolerate dialysis due to fluid shifts across the membrane....What sorts of flow are required scaled up to humans would be required. Could this be run on a CRRT-HF type circuit or a SLED schedule?
2. They use FcMBL adsorbed to dialysis tubing. I only see animal studies. What, if any, interaction does this with human proteins and cell lines. e.g. if it causes hemolysis or Agglutination, this would destroy the utility.
3. What is the observed length of endotoxin/pathogen clearance? Ties back into #1.
4. I presume this is Fc based (the only description I saw was "FcMBL protein was expressed and purified from a stable transfection of CHO-DG44 cells "), is this Fc, human, murine, equine, porcine, leporine, or bovine?
More questions will come up...but I have a lecture to prepare...
I actually predict Watson as potentially increasing medical costs. The issue? Something we call incidentalomas. These are incidental findings that were not expected and rarely result in an identified problem. But we spend a ton of time, money, and effort tracking these down, and they rarely pan out.
A nurse with a printed flowchart will usually give a better diagnosis than a doctor. So replacing (or supplementing) doctors with AI should reduce lawsuits, and improve care.
If that is what you think, then go for it. If you believe that care from a lesser trained individual is better for you, then by all means have at it. I work with nurses, and physicians, and other "healthcare" extenders. Nurses are great a following a well ordered script. They can nail, say, 90-95% of the primary care medical problems out there (e.g. outpatient settings). The problem? If you are part of the 5-10%, they don't do so well (and cost you more money in the process). Most don't have the training or experience to "know what they don't know" or they are Unconsciously incompetent. A good primary physician is at least "Consciously incompetent" to "Unconsciously competent" and can either treat you or refer you. Now I know some are going to tell me that their doctors "know nothing", but I'll bet they know more than most nurses (yes there are physicians who shouldn't be - that's another discussion for another day).
I'm not a practicing engineer, but am one by training. I would imagine that an EM system allows one to "ramp up the power" vs a steam head slamming into a piston and the resulting sudden strain on the plane.
My question is, could you not use something similar for civilian aircraft using a longer ramp up time to lower the amount of fuel on the plane a saving some cost?
NOT the same thing, however in your defense the article does not make this distinction very clear without already knowing the definitions.. Quick clot and related technologies are for "compressible wounds" that are bleeding to the outside. If you can see the source of bleeding, you can usually compress it. TFA references "Non-compressible bleeding". These are typically truncal wounds that require an operation to fix.
This product is more in line to what TFA is referring to: and this product already exists. I know it has been tested on animal models, and I believe is close to, or in human testing. As a side note, this was developed by a trauma surgeon, not a chemist, so I'll give the nod to David King as he has already take into account several aspects of the foam that TFA authors probably have yet to discover along with being much farther ahead in the testing.
For those who didn't follow the links, the bleeding around organs is far from incompressible. In the OR we frequently compress organs or their blood supply to stop bleeding (liver and spleen being _very_ common), (the problem is that they are incompressible from the outside, hence the thought of using a biocompatable foam internally). The problem with internal foam (as anticipated by DK) is that while this pressure may do a good job of stopping the hemorrhage, it may cause too much pressure resulting in abdominal compartment syndrome. There are literally dozen of issues like this that are related to the foam and the consequences of its use, just stopping the bleeding is not enough, you have to deliver a viable patient to definitive care.
Slashdot Mirror
Video about all this. Hardly new "news",
For the record, they're targeting Aedes aegypti mosquitoes, not Anopheles which is the species which carries malaria. Ae aegypti carry yellow fever virus, dengue virus chikungunya virus and Zika viruses. Interestingly Ae aegypti are considered invasive species originally native to Asia. So eradicating them, really shouldn't impact the environment.
I believe the message was from a martian prince there who wanted to reach NASA urgently about some inheritance.
While you are certainly correct that pot is incredibly unlikely to be helpful here you veer into some pretty heavy scare tactics that dont have a lot of truth to them.
"". In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances [americanad...enters.org]"
For starters, medical pot is legal in more states than not so why are we assuming the purchase would be illegal? After that, a small amount of critical thinking quickly brings up the question, why would some one selling weed spend money lacing their product and not tell the person buying? Your own link even states there's no data on the subject.
Here's a nice snopes link debunking the latest panic of fentynal laced weed: https://www.snopes.com/fact-ch...
"And stop claiming that marijuana is harmless. I see too many people land in our ED as a result of this type of self-medication."
While, much like drinking, there are those who will do truely stupid things while high pot is far safer than every day activities like sober driving or manual labor professions.
While you are certainly correct that pot is incredibly unlikely to be helpful here you veer into some pretty heavy scare tactics that dont have a lot of truth to them.
I'm sorry, what scare tactics did I refer to? I have not referred to any well publicized and likely misleading sources used by the war on drugs - I have not referenced the usual claims of lowering IQ or as a gateway drug even though it is reported in a peer reviewed journal. I specfically avoided such sources because I knew someone would attempt to discredit them. What I have given you is clinical experience (19 years now) of issues that I have encountered with actual patients that I have treated. I have had people so strung out on drugs that they failed to recognize a decline in their health that made their condition worse. I have stuporous individuals who have serious medical derangements that we could not determine from their history (they weren't able to talk or were exhibiting paranoia) or from physical exam (they were so out of it I couldn't get they to react to any exam or they refused to cooperate with the exam) Related reference here. It is still illegal to drive after using marijuana in Colorado and California.
In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances [americanad...enters.org]"
For starters, medical pot is legal in more states than not so why are we assuming the purchase would be illegal? After that, a small amount of critical thinking quickly brings up the question, why would some one selling weed spend money lacing their product and not tell the person buying? Your own link even states there's no data on the subject.
Here's a nice snopes link debunking the latest panic of fentynal laced weed: https://www.snopes.com/fact-ch...
While an increasing number of states are allowing "medical marijuana", there are very few registered patients in most states (
You might have missed the news on CD awhile back, ask your doctor if he/she knows what causes Crohn['s]
This is a very interesting article and they may be on to something, but it is far from the first time Crohn’s disease has been attributed to microbes. They make a good argument, but I don't think that this closes the case yet. They specifically note that this is for "Familial Crohn’s Disease" and not all cases are familial. This was also a study that only looked a 9 family, with an n of 20, so this is not a very large study, and these are likely geographically co-located (but they did not give a lot of data on that). I'll avoid a long history of the disease and just place the gentle reminder that correlation is not causation (and in medicine the level of evidence for proof is often much higher than in other sciences). A lot more research needs to go into this - but investigating the complex relations in the gut biome is probably going to yield some very good insights.
So I'll continue with my standard answer for Crohn's that "we still don't know for sure" - but we're getting closer.
This is not a joke. Try smoking (or vaping, or eating) some marijuana. It tends to relax internal muscles and may help you pass it. At worst, it's a cheap, harmless, fun thing to try before going in for a more complicated, potentially needless procedure.
This is not a joke, this is some of the worst advice. Please stop posting uninformed advice that is more harmful than helpful.
Muscle relaxants (of which marijuana is a poor one) are not useful here and are actually contraindicated. This capsule is not hung up on a sphincter, it is likely caught in a stricture and inhibition of peristalsis is not going to help and may make matters worse.
In addition, by consuming marijuana and getting "high" he or she may miss changes in their condition that indicate that they need to get to the hospital emergently (e.g. abdominal pain indicative of intestinal rupture). If they decide to take themselves to the ED, driving while impaired is illegal in all states not to mention just plain dangerous. Once there, again, being under the influence of a psychoactive drugs they may not give a thorough medical history, or it may alter the physical exam findings, possibly leading to a misdiagnosis (even with EMRs - I have seen this happen). Marijuana may also interact with other more useful medications that need to be given leading to further complications. In addition, diagnostic tests may be delayed as they won't be able to properly consent after consuming an substance that alters cognition. In addition, buying drug on the street is very dangerous because you do not know exactly what you are buying (a pharmacology professor of mine proved this in the 80s) - even marijuana can be laced with even more dangerous substances
In short, please don't self-medicate. This is especially true when you have a complex medical condition. Leave the medical advice to someone who is trained and qualified.
And stop claiming that marijuana is harmless. I see too many people land in our ED as a result of this type of self-medication.
Maybe you can use some strong rare-earth magnets to help it along?
This is highly unlikely to work. The problem? You think of the intestine as a linear tube from mouth to colon (then anus), but in reality there are many twists and turns in the intestine (which happens in real time - aka peristalsis). So for any placement of the magnet, you are just as likely to hang it up as to move it along - so doing this yourself won't help - and may actually be harmful if the magnet is strong enough and left in one area too long. That being said....someone has already thought of this. But if you look at the article, it looks like a pretty elaborate setup that likely only exists as a handful centers in the world as this would need to be done in real-time with imaging (looks like a mini CT scanner).
After 12 weeks, the likelihood of this passing on its own is virtually nil, so it will need some help. Double balloon enteroscopy (aka push enteroscopy) can be used if not too far in, and is performed at most university/academic medical centers. Other medical options are descried here. A more aggressive, but not maximally invasive choice would be to bring a surgeon into the mix to do a combination of double balloon enteroscopy and a laparoscopy or just plain old laparoscopy.
Best of luck.
The network is the computer.
- John Burdette Gage (1996)
Really? He lost to Douglas Adams by about 15 years......the successor to Deep Thought was the Earth.
Whoosh!
I believe the HHGTTG summed it up best:
The Hitchhiker’s Guide to the Galaxy defines the Federal Communications Commission as “a bunch of mindless jerks who’ll be the first against the wall when the revolution comes,” with a footnote to the effect that the editors would welcome applications from anyone interested in taking over the post of robotics correspondent. Curiously enough, an edition of the Encyclopedia Galactica that had the good fortune to fall through a time warp from a thousand years in the future defined the Federal Communications Commission as “a bunch of mindless jerks who were the first against the wall when the revolution came.”
-- Douglas Adams, The Hitchhiker's Guide to the Galaxy
I would love it if everyone who was interviewed live yelled "Alexa, play 'Never gonna give you up'" randomly while on the air. Mass panic at Amazon. The Rick-rolling to end all Rick-rolling!
First, there have been no reported deaths from this infection as per the article, so how exactly is this deadly? Dangerous, potentially deadly? So, please, lets title these articles responsibly. The remainder of this post is not meant to bash the parent, just to define terms and clarify concepts. My opinion is at the end.
Not a doctor, but there is only a little overlap between antibiotics and antifungal medications.
The term antibiotic covers both anti-bacterial agents (e.g. penicillin) used against bacteria, and anti-fungals (e.g. fluconaole/Diflucan), and technically, they also refer to anti-virals (e.g. aciclovir), but in the most common use, antibiotics refer to antibacterials, and never to antivirals. There are no medications that treat both bacteria (prokaryotes [no nucleus]), fungus (eukaryotes [true nucleus]) simultaneously; yes, bleach (sodium hypochlorite) can destroy both, but internal use is discouraged [and as referenced in the wikipedia article, your body's neutrophils (a type of white blood cell - cells that fight infection) uses hypochlorous acid as an antimicrobial . So.....yes and no. [sorry that kept getting longer and longer]
This stuff is resistant to Diflucan (I'm not trying to spell the generic name correctly right now),
Flu con a zole - that's not too hard....Talimogene Laherparepvec...that's hard. :-)
which is often handed out with much less oversight than antibiotics.
Ummm, no. You can get pretty powerful topical antibiotics and topical antifungals over the counter. Fluconazole is an oral antifungal that still requires a prescription (at least in the US and other "responsible" countries).
Any bio-female could probably get a few doses for a yeast infection without seeing their doctor; calling in and asking is all most require since it is a common ailment.
It is a common ailment, but it is also a true infection that can be cultured and proven, and usually requires treatment. (I don't want you to poo-poo this aliment :-), pretty miserably for those afflicted), and unless there is a well established relationship between physician and patient, an exam is required (and strongly encouraged to rule out other more dangerous diagnoses).
The problem is that many primary care doctors have been told that C. albicans (the common human strain) can not become resistant. I was told the same, only to be corrected by a very indignant Tropical and Infectious Disease specialist who had seen that first line drug become useless in a few cases.
I see fluconazole resistant candida albicans frequently (reported 7% resistance rate), but I work at a tertiary care referral center, so YMMV. Never been under the illusion that it could not become resistant. Every organism (meaning microbial species) given enough time and opportunity can become resistant to just about anything.....The only thing that microbial organisms will never become resistant to is fire, well heat anyways (shout out to the the post below).
But this doesn't mean we need to panic and shut down Madagascar. There are other classes of drugs, like the old standby nystatin, and other families of antifungal medications in the larger azole drug category. This should be treatable if caught early. The danger is that drugs like nystatin can not be absorbed so
My first thought:
Great, when's it going to run for Congress?
How Do I Handle Interruptions At Work? I set the perpetrator ablaze.
When I was writing code, I personally found a strategically placed Claymore mine usually preempts interruptions. Tripwires prevent me from even having to turn around.....
N.B. "Front towards enemy", means just that......
Let me know if you find the episodes!
Savage 1 - 2x1 Hard Water, Part 1>/P
and
Savage 1 - 2x2 Hard Water, Part 2
It was one of the ideas pitched to Montgomery Brewster (Richard Pryor) in the movie Brewster's Millions, execpt the guy wanted to tow it from the Arctic.
I think you're on the right track....I have not RTFA, but the synopsis raises some concern about interpreting the conclusion. The data was taken from "General Internal Medicine Division", which are, typically, first line or Primary Care Physicians (PCPs). Often they will make a diagnosis based on their generalized knowledge of a medical problem and often refer them to a sub-specialist (i.e. you have trouble breathing with exertion, you find you need to sleep on multiple pillows, your ankles are swollen and you physical exam and office EKG lead me to refer you to a cardiologist (sub-specialist)) - so yes, the opinion will be different a lot of the time....the generalist can't know everything that a specialist can, but the generalist often triages the problem to someone who does know more.
This could explain the "Among those with updated diagnoses, 66% received a refined or redefined diagnosis, while 21% were diagnosed with something completely different". It'd be interesting to see how they correlated this.
How do we boost the strength far enough to eliminate cancer?
In short: you can't. Cosmic radiation is just a small part of the complex system that can trigger cancer. Other aspects include: genetic make-up, environment (carcinogens) and the inherent error rate in the DNA copying machinery (missense, frameshifts, slippage, etc) [to name a few off the top of my head - I don't treat cancer]. And before you go down there....those imperfect copies are what leads to genetic variation (important to fend off predators both macro and microscopic) and evolution. Cancer is just about inevitable in any DNA based system
Or more likely there is only so much room to fit people in the Bay Area
Ummm, no. More likely this is another bubble, and we're seeing the first signs its going to pop. How many of these "businesses" that sell "free" products are actually turning a profit? And how many are just waiting to be bought out? Sound familiar? It's the tech version of flipping houses.
I'd also be interested to see how much is contributed back by alum from each major. I'm sure that the liberal arts major who job is to ask "You want fries with that?" will give back a lot less than the engineer pulling 120k while designing chips.
When I see the word Toxins, my bullshit radar activates
I am a physician and yes, my BS meter usually goes up when people who have no understanding of human anatomy, physiology, histology, biochemistry, or pathology start rambling on about toxins. But take it from person who deals with sepsis and critical ill patients on a weekly basis. Bacterial endotoxins are the real deal. There are a significant source of morbidity and mortality in severely ill patients. Also, please realize that this research is in collaboration with Boston Children's Hospital and Harvard's Engineering department.
That being said, I pulled the original article and on first read, it seems to be a potential game-changer. My questions:
1. They liken this to dialysis. Many critically ill patients can not tolerate dialysis due to fluid shifts across the membrane....What sorts of flow are required scaled up to humans would be required. Could this be run on a CRRT-HF type circuit or a SLED schedule?
2. They use FcMBL adsorbed to dialysis tubing. I only see animal studies. What, if any, interaction does this with human proteins and cell lines. e.g. if it causes hemolysis or Agglutination, this would destroy the utility.
3. What is the observed length of endotoxin/pathogen clearance? Ties back into #1.
4. I presume this is Fc based (the only description I saw was "FcMBL protein was expressed and purified from a stable transfection of CHO-DG44 cells "), is this Fc, human, murine, equine, porcine, leporine, or bovine?
More questions will come up...but I have a lecture to prepare...
Unfortunately, treatment will still cost more than ever due to lawsuits and drug costs.
Lawsuits are often caused by human error: sleep deprived doctors, or overconfident doctors making bad diagnoses on insufficient information.
No, actually they are not. The leading cause of lawsuits is poor communication. And if you want to believe a lawyer the top two leading causes are surgical misadventures and issues with child birth. Missed diagnosed probably comes in third.
I actually predict Watson as potentially increasing medical costs. The issue? Something we call incidentalomas. These are incidental findings that were not expected and rarely result in an identified problem. But we spend a ton of time, money, and effort tracking these down, and they rarely pan out.
A nurse with a printed flowchart will usually give a better diagnosis than a doctor. So replacing (or supplementing) doctors with AI should reduce lawsuits, and improve care.
If that is what you think, then go for it. If you believe that care from a lesser trained individual is better for you, then by all means have at it. I work with nurses, and physicians, and other "healthcare" extenders. Nurses are great a following a well ordered script. They can nail, say, 90-95% of the primary care medical problems out there (e.g. outpatient settings). The problem? If you are part of the 5-10%, they don't do so well (and cost you more money in the process). Most don't have the training or experience to "know what they don't know" or they are Unconsciously incompetent. A good primary physician is at least "Consciously incompetent" to "Unconsciously competent" and can either treat you or refer you. Now I know some are going to tell me that their doctors "know nothing", but I'll bet they know more than most nurses (yes there are physicians who shouldn't be - that's another discussion for another day).
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I'm not a practicing engineer, but am one by training. I would imagine that an EM system allows one to "ramp up the power" vs a steam head slamming into a piston and the resulting sudden strain on the plane.
My question is, could you not use something similar for civilian aircraft using a longer ramp up time to lower the amount of fuel on the plane a saving some cost?
We've been using this stuff for 10 years already in the military. You can buy it on Amazon.
http://www.amazon.com/gp/product/B001BCNTHC/ref=oh_aui_detailpage_o03_s00?ie=UTF8&psc=1
NOT the same thing, however in your defense the article does not make this distinction very clear without already knowing the definitions.. Quick clot and related technologies are for "compressible wounds" that are bleeding to the outside. If you can see the source of bleeding, you can usually compress it. TFA references "Non-compressible bleeding". These are typically truncal wounds that require an operation to fix.
This product is more in line to what TFA is referring to: and this product already exists. I know it has been tested on animal models, and I believe is close to, or in human testing. As a side note, this was developed by a trauma surgeon, not a chemist, so I'll give the nod to David King as he has already take into account several aspects of the foam that TFA authors probably have yet to discover along with being much farther ahead in the testing.
For those who didn't follow the links, the bleeding around organs is far from incompressible. In the OR we frequently compress organs or their blood supply to stop bleeding (liver and spleen being _very_ common), (the problem is that they are incompressible from the outside, hence the thought of using a biocompatable foam internally). The problem with internal foam (as anticipated by DK) is that while this pressure may do a good job of stopping the hemorrhage, it may cause too much pressure resulting in abdominal compartment syndrome. There are literally dozen of issues like this that are related to the foam and the consequences of its use, just stopping the bleeding is not enough, you have to deliver a viable patient to definitive care.
I went to a quantum factory, but since it wasn't moving, I couldn't find it. *sigh*.