I must have missed the news story of the "green" states erecting semi-permeable membranes around themselves that can keep out pollution from the other "non-green" states. Otherwise, why would they only benefit from those cars being driven solely in their state?
HPV can cause cancer over a very long time and it's not definite that anything will even develop. With the kind of gene transfer they use to make these cancer stem cells you would almost instantly have cancer where ever the virus dropped it's payload. The field of gene therapy (transfer) is still young but sooner or later they will be very good at targeting specific areas or cells in the body. They may also have better transfection rates and even better cancer inducing genes. This leads to possibilities that something like Ebola could never give. I'm not sure I have a nefarious enough mind to figure out why targeted cancer might be useful over outright death by something like Ebola but I'm sure there is someone out there who could.
Scratch that, I just thought of one. If you wanted someone dead and wanted it to look natural then you would never use Ebola. That would scream foul play. On the other hand, giving them a huge, inoperable brain tumor wouldn't look very suspicious. The only way to tell anything was done would be postmortem and even then it would have to be a very intensive investigation to find the inserted genes. And that's assuming they can't make the genes look like the natural mutations that bring about cancer normally. All this stuff is really far away from reality and in no way should it be used to put down the current science which should prove to be very useful in the study of cancer.
Not really, you would need the cells to be immunologically compatible to each person you wanted to infect. That would be harder than a large number of other ways to hurt them. On the other hand, a biological weapon could come from the method they use to turn the cells into cancer stem cells. This generally involves a gene transfer using a virus vector. That kind of virus could be used to create these types of cells inside someone. I don't think large scale virus vector weapons are currently feasible but it may be something to worry about in the future.
Considering that Darwin's observations apply to populations as a whole and never to individuals, when it comes to evolution and diversity, then I don't see how you could take it any other way. http://en.wikipedia.org/wiki/Evolution
Actually, it is not the first to use a genetic model of schizophrenia in a mouse. There are multiple strains that come to mind as "previous art." The genes Neuregulin-1, Disbindin, COMT, and last but not least DISC (which stands for disrupted in schizophrenia) have all been used in transgenic mice as model of schizophrenia. My lab personally uses 2 of these and collaborates with groups that have the others. That's not to say that this new strain of mouse isn't useful. The general consensus regarding schizophrenia is that quite a few genes are at work as well as environmental factors, so adding another mouse model to the effort always helps.
You have got to be joking. The original poster wanted a phone without camera, mp3, low battery life and high price for his mother. Those phones all meet the requirements with near 4 hour talk times and 300+ hours standby. Some of them have very nice large text display which is also a nice plus for many elderly users. Just because the thing has a calculator, memo recorder, and calendar in a menu option doesn't make it more expensive or kill the battery life. If its just going to be used as a basic phone then they wouldn't need to ever delve that deep. The jist of his post was about the useless bundling of extra equipment that would drive up price and kill battery life. Next time try thinking for a few minutes before spouting off the insults.
Or did you just want to get a post on slashdot? I went to verizonwireless.com and found multiple "just cell phone" phones. The LG VX3400, Verizon Wireless PN-300, Nokia 2366i, and more. That took all of 2 minutes, dont you think you could have done the same thing?
I'm going to write this regarding the effects of nicotine on the brain because that is my area of research. Effects on peripheral systems may be different.
The problem with simply using nicotine as the beneficial drug is that there are both positive and negative effects of nicotine on the brain. It is believed that the effects are based on the activation of a vast array of nicotinic ACh receptors. For instance, many of the positive cognitive effects of nicotine have been linked with the alpha-7 and alpha-4 beta-2 receptor types. Therefore, many of the drugs currently being studied target those receptors individually. Some of the receptor subtypes are linked with negative effects, so any of these synthetic drugs that are specific to the beneficial receptors types are going to be used with priority over nicotine. This also ties in with creating drugs for treating nicotine addiction, which is a huge field of research at the moment that I am pretty sure big tobacco doesn't want anything to do with.
You should really know more about a subject before you go on spouting things like "You can be sure the tobacco industry is funding this research." A large portion of this funding is coming from the NIH and one of the main areas of study is smoking cessation. That most certainly does not benefit the tobacco companies. In addition, none of these studies would suggest a cigarette, dip or chew as the route of administration so once again no benefit. If anything, the pharm companies stand to gain while the tobacco companies stand to lose because the drugs in question are all synthetic nicotine like substances that are patented and solely under big pharma control.
Oops, I didn't read the rest of your comment before replying or I would have seen the last line about med school. Yes I am applying to med school so that is the basis of my frustration.
I'm sorry you have a hard time believing my situation. I was an engineering major in undergrad so the majority of my basic science classes were covered that year (e.g. Chem, Physics, Calc 1 and 2). I am currently applying to medical school and that is where the problem begins. Because my grades were not spectacular that year, my science GPA as calculated by the medical school application process, is quite low even though I had a 3.5 or better for the rest of my time at college. Nothing counts a science GPA for med school except those core classes. It is not necessarily an admissions officer that is black balling me but rather a specific cutoff number that is probably evaluated by a computer system. Therefore, no one would even see my other years unless I met the minimum requirements from those freshman grades.
I can't stress enough that you will, at some point, regret it if you graduate with bad grades. Having an extra year of school won't matter at all to most recruiters or schools (if you decide to try grad programs). I had a bad first year in school due to medical problems. I had surgery over the summer and did very well for the next 3 years. My school did not let me repeat those first year classes and I have been suffering ever since from one bad year. Without knowing your specific grades I can't say much else but for example if you have less than a 3.0/4.0 GPA and that extra year will bring you above a 3.0 then I don't think you should even consider any alternatives.
I may not be reading this properly but I don't see the blocking of all DVD copying in the amendment:
6.4. Certain Requirements for DVD Products. DVD Products, alone or in combination with other DVD Products, shall not be designed to descramble scrambled CSS Data when the DVD Disc containing such CSS Data and associated CSS Keys is not physically present in the DVD Player or DVD Drive (as applicable), and a DVD Product shall not be designed to make or direct the making of a persistent copy of CSS Data that has been descrambled from such DVD Disc by such DVD Product. I read that they want to prevent a copy being made of the descrambled data stream coming out of the product. As far as I know that is already blocked in most devices. I can't see any interpretation where unencrypted data will be blocked from being copied. I don't necessarily agree with this limitation but I don't see it having much of any impact due to the availability of CSS decryption tools.
The link you posted states that private companies may choose not to accept some forms of legal tender. I suspect it specifically mentions private business because publicly funded institutions, such as the school in question, are required to accept ALL forms of legal tender.
Whoa, wait and minute. I thought that Apple made a big fuss about not allowing the Cell companies to lock users in to long term contracts with subsidized phones and that was why were were going to pay 500+ for the iPhone. The end of the commercial indicated we have to sign a 2 year minimum plan with AT&T. I certainly don't want to pay out the ass for this phone and still get locked into a company.
I'm sorry, but did you see the second Pirates movie? It was the worst piece of filler/advertisement trash I have ever had the displeasure of viewing. I would rather watch the second and third matrix movies over and over than have to see that again and I didn't really like them much at all. With that in mind I don't think a difference in quality of the films is a big factor in HD sales. Most likely, pirates is selling more because it's more recent, people haven't watched it over and over on HBO and TNT, and the new one in theaters is generating interest.
I don't really know where the New York AG is coming up with the "no service at all" comment. While I'm not sure about their problems with promotional financing, rebate offers, and billing activity; when I am forced to interact with dell for customer support on work computers I have always had good experiences. Maybe it is because I can fix most software issues and the only time I really go to them is when something fails. They have replace what's broken quite readily. Even if his problem is with their other practices I think he's over stating the support problems. Don't get me wrong, I am definitely not a fan of dell but I don't like them because of the proprietary hardware and the preloaded bloatware.
I can think of three possibilities for explanation.
1. Maybe Carl and buddies were using a mailing list that had the email address in question added to it by accident. I have seen this happen at my work and sometimes it takes multiple emails just to get someone to take you off the list. I can imagine a reporter who ended up on the list would not try very hard at all to be removed.
2. In the same line of thought, maybe he found an insider who could add him to the list. Sounds like something that a reporter might try for some inside info on a political party. If found out, he could always claim reason 1 from above.
3. He recovered the emails by some less accepted (more illicit) means and it's much more convenient to claim they received them at the Mew York offices.
How exactly do you propose to stop an INTERNATIONAL crime ring with US legislation? All they will be able to do is arrest the little guys that are actually selling the stuff here. The big fish will keep on running their criminal enterprises from some place outside our jurisdiction.
No price was offered. They asked him to come up with one and then slammed him for doing just that. The responsible thing to do, for someone who has been helping them for over 2 years, would have been to make a counter offer that they found reasonable. Instead they decided to mount a smear campaign and basically spit in his face.
Also, it was taken from him, at least in part. He no longer has the same myspace address and his page is down until he picks a new one.
I was trying to make the best analogy I could given that no land is free. Imagine that he got free land (equivalent to a myspace page) and then built the free kitchen. Even if the affiliated company supplied the stuff for the kitchen, they can not just take the whole place from him because he did it with their permission.
Thank you for ignoring everything else I wrote and simply attacking my analogy.
First, the work was volunteer but the ownership of the site is not. Let's say I build an add on to my house in the name of a local food shelter (with their permission and support) and volunteer my time to feed people in need. They then want to take over the place because it has become such a huge success. They are not entitled to have it simply because I was volunteering my time, the volunteering was simply the time put into it until then. The price to take it over from me is whatever price I set, especially if they come to me asking for an offer.
Secondly, there are plenty of cases where a simple website has gone from being pretty much worthless to a business with income. Just because you think a myspace page can not make the same transition does not make it fact.
The bottom line is this guy spend years working with them and gaining a huge following for the campaign. They asked him for a price so they must have felt like he had earned something. It was very nasty to turn around and start badmouthing him for asking more then they were willing to pay. The decent thing to do for someone, even if they haven't spent years furthering your cause, is to make a counter offer that you believe is fitting.
It is sad too, I have been a huge Obama fan, but the way his campaign staff have managed this so far has really damaged my opinion of the people in his camp.
Did you completely ignore the article?!? They ASKED HIM for a price because they wanted to take over the site he had built. It had been volunteer until then and he was fine continuing to volunteer but since they wanted to take over then a payment is perfectly acceptable.
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I must have missed the news story of the "green" states erecting semi-permeable membranes around themselves that can keep out pollution from the other "non-green" states. Otherwise, why would they only benefit from those cars being driven solely in their state?
HPV can cause cancer over a very long time and it's not definite that anything will even develop. With the kind of gene transfer they use to make these cancer stem cells you would almost instantly have cancer where ever the virus dropped it's payload. The field of gene therapy (transfer) is still young but sooner or later they will be very good at targeting specific areas or cells in the body. They may also have better transfection rates and even better cancer inducing genes. This leads to possibilities that something like Ebola could never give. I'm not sure I have a nefarious enough mind to figure out why targeted cancer might be useful over outright death by something like Ebola but I'm sure there is someone out there who could.
Scratch that, I just thought of one. If you wanted someone dead and wanted it to look natural then you would never use Ebola. That would scream foul play. On the other hand, giving them a huge, inoperable brain tumor wouldn't look very suspicious. The only way to tell anything was done would be postmortem and even then it would have to be a very intensive investigation to find the inserted genes. And that's assuming they can't make the genes look like the natural mutations that bring about cancer normally. All this stuff is really far away from reality and in no way should it be used to put down the current science which should prove to be very useful in the study of cancer.
Not really, you would need the cells to be immunologically compatible to each person you wanted to infect. That would be harder than a large number of other ways to hurt them. On the other hand, a biological weapon could come from the method they use to turn the cells into cancer stem cells. This generally involves a gene transfer using a virus vector. That kind of virus could be used to create these types of cells inside someone. I don't think large scale virus vector weapons are currently feasible but it may be something to worry about in the future.
Considering that Darwin's observations apply to populations as a whole and never to individuals, when it comes to evolution and diversity, then I don't see how you could take it any other way. http://en.wikipedia.org/wiki/Evolution
Actually, it is not the first to use a genetic model of schizophrenia in a mouse. There are multiple strains that come to mind as "previous art." The genes Neuregulin-1, Disbindin, COMT, and last but not least DISC (which stands for disrupted in schizophrenia) have all been used in transgenic mice as model of schizophrenia. My lab personally uses 2 of these and collaborates with groups that have the others. That's not to say that this new strain of mouse isn't useful. The general consensus regarding schizophrenia is that quite a few genes are at work as well as environmental factors, so adding another mouse model to the effort always helps.
You have got to be joking. The original poster wanted a phone without camera, mp3, low battery life and high price for his mother. Those phones all meet the requirements with near 4 hour talk times and 300+ hours standby. Some of them have very nice large text display which is also a nice plus for many elderly users. Just because the thing has a calculator, memo recorder, and calendar in a menu option doesn't make it more expensive or kill the battery life. If its just going to be used as a basic phone then they wouldn't need to ever delve that deep. The jist of his post was about the useless bundling of extra equipment that would drive up price and kill battery life. Next time try thinking for a few minutes before spouting off the insults.
Or did you just want to get a post on slashdot? I went to verizonwireless.com and found multiple "just cell phone" phones. The LG VX3400, Verizon Wireless PN-300, Nokia 2366i, and more. That took all of 2 minutes, dont you think you could have done the same thing?
I'm going to write this regarding the effects of nicotine on the brain because that is my area of research. Effects on peripheral systems may be different.
The problem with simply using nicotine as the beneficial drug is that there are both positive and negative effects of nicotine on the brain. It is believed that the effects are based on the activation of a vast array of nicotinic ACh receptors. For instance, many of the positive cognitive effects of nicotine have been linked with the alpha-7 and alpha-4 beta-2 receptor types. Therefore, many of the drugs currently being studied target those receptors individually. Some of the receptor subtypes are linked with negative effects, so any of these synthetic drugs that are specific to the beneficial receptors types are going to be used with priority over nicotine. This also ties in with creating drugs for treating nicotine addiction, which is a huge field of research at the moment that I am pretty sure big tobacco doesn't want anything to do with.
You should really know more about a subject before you go on spouting things like "You can be sure the tobacco industry is funding this research." A large portion of this funding is coming from the NIH and one of the main areas of study is smoking cessation. That most certainly does not benefit the tobacco companies. In addition, none of these studies would suggest a cigarette, dip or chew as the route of administration so once again no benefit. If anything, the pharm companies stand to gain while the tobacco companies stand to lose because the drugs in question are all synthetic nicotine like substances that are patented and solely under big pharma control.
Oops, I didn't read the rest of your comment before replying or I would have seen the last line about med school. Yes I am applying to med school so that is the basis of my frustration.
I'm sorry you have a hard time believing my situation. I was an engineering major in undergrad so the majority of my basic science classes were covered that year (e.g. Chem, Physics, Calc 1 and 2). I am currently applying to medical school and that is where the problem begins. Because my grades were not spectacular that year, my science GPA as calculated by the medical school application process, is quite low even though I had a 3.5 or better for the rest of my time at college. Nothing counts a science GPA for med school except those core classes. It is not necessarily an admissions officer that is black balling me but rather a specific cutoff number that is probably evaluated by a computer system. Therefore, no one would even see my other years unless I met the minimum requirements from those freshman grades.
I can't stress enough that you will, at some point, regret it if you graduate with bad grades. Having an extra year of school won't matter at all to most recruiters or schools (if you decide to try grad programs). I had a bad first year in school due to medical problems. I had surgery over the summer and did very well for the next 3 years. My school did not let me repeat those first year classes and I have been suffering ever since from one bad year. Without knowing your specific grades I can't say much else but for example if you have less than a 3.0/4.0 GPA and that extra year will bring you above a 3.0 then I don't think you should even consider any alternatives.
The link you posted states that private companies may choose not to accept some forms of legal tender. I suspect it specifically mentions private business because publicly funded institutions, such as the school in question, are required to accept ALL forms of legal tender.
Whoa, wait and minute. I thought that Apple made a big fuss about not allowing the Cell companies to lock users in to long term contracts with subsidized phones and that was why were were going to pay 500+ for the iPhone. The end of the commercial indicated we have to sign a 2 year minimum plan with AT&T. I certainly don't want to pay out the ass for this phone and still get locked into a company.
I'm sorry, but did you see the second Pirates movie? It was the worst piece of filler/advertisement trash I have ever had the displeasure of viewing. I would rather watch the second and third matrix movies over and over than have to see that again and I didn't really like them much at all. With that in mind I don't think a difference in quality of the films is a big factor in HD sales. Most likely, pirates is selling more because it's more recent, people haven't watched it over and over on HBO and TNT, and the new one in theaters is generating interest.
I don't really know where the New York AG is coming up with the "no service at all" comment. While I'm not sure about their problems with promotional financing, rebate offers, and billing activity; when I am forced to interact with dell for customer support on work computers I have always had good experiences. Maybe it is because I can fix most software issues and the only time I really go to them is when something fails. They have replace what's broken quite readily. Even if his problem is with their other practices I think he's over stating the support problems. Don't get me wrong, I am definitely not a fan of dell but I don't like them because of the proprietary hardware and the preloaded bloatware.
I can think of three possibilities for explanation.
1. Maybe Carl and buddies were using a mailing list that had the email address in question added to it by accident. I have seen this happen at my work and sometimes it takes multiple emails just to get someone to take you off the list. I can imagine a reporter who ended up on the list would not try very hard at all to be removed.
2. In the same line of thought, maybe he found an insider who could add him to the list. Sounds like something that a reporter might try for some inside info on a political party. If found out, he could always claim reason 1 from above.
3. He recovered the emails by some less accepted (more illicit) means and it's much more convenient to claim they received them at the Mew York offices.
There are potentially too many potentialities in the summary.
How exactly do you propose to stop an INTERNATIONAL crime ring with US legislation? All they will be able to do is arrest the little guys that are actually selling the stuff here. The big fish will keep on running their criminal enterprises from some place outside our jurisdiction.
Both Tomb Raider movies did quite well so you should not be quite so dismissive.
Tomb Raider 1, World wide gross $274,703,340
Tomb Raider 2, World wide gross $156,505,388
Compare those one of the flops you mention:
Super Mario Bros, Gross (only domestic) $20,915,465
Or even a movie that a lot of slashdot users love:
Serenity, World wide gross $38,869,464
No price was offered. They asked him to come up with one and then slammed him for doing just that. The responsible thing to do, for someone who has been helping them for over 2 years, would have been to make a counter offer that they found reasonable. Instead they decided to mount a smear campaign and basically spit in his face.
Also, it was taken from him, at least in part. He no longer has the same myspace address and his page is down until he picks a new one.
I was trying to make the best analogy I could given that no land is free. Imagine that he got free land (equivalent to a myspace page) and then built the free kitchen. Even if the affiliated company supplied the stuff for the kitchen, they can not just take the whole place from him because he did it with their permission.
Thank you for ignoring everything else I wrote and simply attacking my analogy.
First, the work was volunteer but the ownership of the site is not. Let's say I build an add on to my house in the name of a local food shelter (with their permission and support) and volunteer my time to feed people in need. They then want to take over the place because it has become such a huge success. They are not entitled to have it simply because I was volunteering my time, the volunteering was simply the time put into it until then. The price to take it over from me is whatever price I set, especially if they come to me asking for an offer.
Secondly, there are plenty of cases where a simple website has gone from being pretty much worthless to a business with income. Just because you think a myspace page can not make the same transition does not make it fact.
The bottom line is this guy spend years working with them and gaining a huge following for the campaign. They asked him for a price so they must have felt like he had earned something. It was very nasty to turn around and start badmouthing him for asking more then they were willing to pay. The decent thing to do for someone, even if they haven't spent years furthering your cause, is to make a counter offer that you believe is fitting.
It is sad too, I have been a huge Obama fan, but the way his campaign staff have managed this so far has really damaged my opinion of the people in his camp.
Did you completely ignore the article?!? They ASKED HIM for a price because they wanted to take over the site he had built. It had been volunteer until then and he was fine continuing to volunteer but since they wanted to take over then a payment is perfectly acceptable.