Xmax -
please get in touch if you wish, but I did some Apache benchmarks with Geo::IP and Pear's GeoIP, both using Maxmind's free database and while Pear was quering at 1/5ms on 100 concurrent connections, Geo::IP was answering 1:180ms but with apache balking after 2000 request...
This really disappointed me and as such we only run PHP on the maxmind dbase....
I never looked into why the delay was there, but care to comment?
Replying to my own question, but I think I found the most complete OS project out there for geolocation log statistics....
I've been playing with phpMyVisites and it looks a very nice and thorough implementation of what I was looking for.
Although it's method for country geolocation is a bit *cough* rough, I think a module to hook into Space Cowboy's hostip.info shouldn't be too difficult...
The only problem with it is it uses mysql to store the logs *grrrrr*
Your experience is different to mine. I'm with the parent - I live in France and Google will default to google.fr, but if I click "Go to Google.com in English" I get Google.com> I know it is google.com since google.fr has to filter certain nazi content to comply with State laws, yet Google.com doesn't. Additionally, I get American-localised content.
It can be beneficial to the user also... like it states on the analytics website, it is integrated with adwords, so if you have an adword for blondes and most of your visitors are using the search term brunettes then you know to switch keywords to increase ROI
Ok, that last one is my pure speculation, but isn't it funny how there is not one teeny weeny mention of battery life anywhere in the MacBook Pro blurb... whereas the Powerbook G4 blurb gets prominent place on the 'features' list as Extra-long battery Be productive for up to 5.5 hours...etc
Early adopters will not be happy.
Especially if they rely on good old dialup...
Not necessarily, and to delve a bit into the science, the receptor they were looking at, ACVR has an orthologue, ACVR2. Mice lacking ACVR (Acvr-/-) OR mice lacking ACRV2 (Acvr2-/-) both had larger muscles. However, Acvr-/-; Acvr2-/- double homozygous knockouts are not viable, so it is probable that both receptors regulate muscle growth.
I didn't read the scientific article fully, but it's probably why it's only in PNAS and not Nature or Science.
The published work is here, which explains that the gene affected is myostatin.
Myostatin, aka GDF-8, is only expressed in skeletal muscle and not cardiac or smooth muscle: "There are several TGFb s subtypes which are based on their related structure. One such member is called growth and differentiation factors (GDF) and specifically regulates growth and differentiation. GDF-8, also called myostatin, is the skeletal muscle protein associated with the double muscling in mice and cattle."
It's called research and discovery, since it's is looking at things we know nothing or little about and discovery. Who's to know what we will discover tomorrow? Clearly you know we will not find anything useful, but then what do you or I or the next boffin know?
Nobody knows, that's why it's worth investing in. To find out.
Please, think a little outside of your own confines.
Every biological discovery "may lead to new breakthroughs in aging/cancer/AIDs/impotency treatment", yet so few do.
Maybe why they say may? At any rate, treatments today are the children of research and as a result we
Live longer
can treat cancer (some being near 100% successful)
treat AIDS
treat impotency
There is no magic bullet, which people like you believe, that treats and cures all. Even your own words say there are yet so few. Isn't the fact that are are some make it all worthwhile?
Or would you rather take away funding for medical research and pump it into Homeland Defense instead?
...insomuch as it proved a right fiasco in Germany, who now "plans to [scrap the idea and] reintroduce a sticker system for collecting tolls, which it had abandoned last August."
But then again, Americans can succeed where others have failed.
From wikipedia: The 5300 series is widely considered Apple's worst product of the 1995-1996 time period where the company teetered on the brink of death. In its 5300ce incarnation with a TFT of 800x600 pixels, a 117 MHz PPC, 32 MB on-board RAM and hot-swappable drive bay, the 5300ce was quite ahead of other laptop models at the time, but by far failed to meet the quality standard expected for the price. Many models shipped dead on arrival, and a few 5300's used at Apple actually burst into flames due to problems with then-new Lithium Ion batteries made by Sony (earning the 5300 the nickname "Hindenbook", after the Hindenburg disaster). While no consumer models suffered this fate, Apple was forced to recall the entire product line and delay its availability while they downgraded to proven nickel metal hydride batteries. Apple's much-publicized PowerBook 5300 product placement in the film Mission Impossible turned to disaster when the PowerBooks still hadn't arrived in stores when the movie premiered in theaters. After Apple offered an Extended Repair Program, the series turned into a remarkably attractive machine, but never lost its reputation.
I didn't read anything in the article which says it can amplify DNA like a traditional PCR in minutes. Of course it can only be as fast as the speed of the reaction - 15-30" to efficiently denature a 3kb strand, the speed of the enzyme (~60nt/sec) and of course the primer annealing step - one of the nice things about current PCR (walled tubes) is that the temperature drops to the annealing temperature gradually. If the temperature drop was instantaneous, then you risk mal-annealed primers. At any rate, if you say 30" to allow annealing, and 1 minute for the enzyme to amplify ~3.5kb DNA, then you still have to wait 1 hour for a 30-cycle reaction.
And of course, there are the thermodynamic encumbrances imposed by walled PCR tubes - unless the machine was disposable, I wouldn't like to eliminate the security of x-contamination of using disposable tubes.
Transforming the national grid into a carrier of electronic information or using it for internet access is nothing new, and has been on trial in (at least) the UK and France - my last apt in Marseille had a 1MBit connection through the electricity socket, accessed via a clunky, but efficient modem.
Don't overlook the possibility that if the EU's governments move to the right, this case may be damaged.
Just as well then that Spain has a new socialist govt, England isn't voting until late next year, France's centre-right govt, well hates America, and German's Schroeder isn't going anywhere anytime soon.
Oh, wait, you mean the the govts from the new EU members. Yup, those old Soviet Bloc guys have really got some clowt.
As per pretty much all AppleInsider's articels, it starts off According to reliable sources.... Plus they have only about a 15-20% success rate on their rumours.
Are they trying to increase their 'success' rate on their predictions by quoting other, a little more reliable, news sources?
More importantly, why is Slashdot becoming part of the rumour mill?
please get in touch if you wish, but I did some Apache benchmarks with Geo::IP and Pear's GeoIP, both using Maxmind's free database and while Pear was quering at 1/5ms on 100 concurrent connections, Geo::IP was answering 1:180ms but with apache balking after 2000 request...
This really disappointed me and as such we only run PHP on the maxmind dbase....
I never looked into why the delay was there, but care to comment?
Replying to my own question, but I think I found the most complete OS project out there for geolocation log statistics....
I've been playing with phpMyVisites and it looks a very nice and thorough implementation of what I was looking for.
Although it's method for country geolocation is a bit *cough* rough, I think a module to hook into Space Cowboy's hostip.info shouldn't be too difficult...
The only problem with it is it uses mysql to store the logs *grrrrr*
OpenLayers looks slick!
make that Eleksen
Try Elekson for their pressure sensitve fabrics. You can even integrate iPod controls into the sleeve!
They're not alone - try Luminex for fibre optic threads in clothes and Elekson for pressure sensitive fabrics....
OS 9 was the death of the Classic Mac OS.
The ability of OS X to multitask aside, OS 8.6 was as stable as OS X is today.
Your experience is different to mine. I'm with the parent - I live in France and Google will default to google.fr, but if I click "Go to Google.com in English" I get Google.com> I know it is google.com since google.fr has to filter certain nazi content to comply with State laws, yet Google.com doesn't. Additionally, I get American-localised content.
So why then don't they include a USB modem dongle with the package? You know, like the DVI-VGA dongle included with all powerbooks.
It can be beneficial to the user also... like it states on the analytics website, it is integrated with adwords, so if you have an adword for blondes and most of your visitors are using the search term brunettes then you know to switch keywords to increase ROI
It looks like you have to sacrifice a lot...
Ok, that last one is my pure speculation, but isn't it funny how there is not one teeny weeny mention of battery life anywhere in the MacBook Pro blurb... whereas the Powerbook G4 blurb gets prominent place on the 'features' list as Extra-long battery Be productive for up to 5.5 hours...etc
Early adopters will not be happy. Especially if they rely on good old dialup...if you notice in the article, he won the consoles. So, while yes, they were free, he had to win them to get them.
Not necessarily, and to delve a bit into the science, the receptor they were looking at, ACVR has an orthologue, ACVR2. Mice lacking ACVR (Acvr-/-) OR mice lacking ACRV2 (Acvr2-/-) both had larger muscles. However, Acvr-/-; Acvr2-/- double homozygous knockouts are not viable, so it is probable that both receptors regulate muscle growth.
I didn't read the scientific article fully, but it's probably why it's only in PNAS and not Nature or Science.
The published work is here, which explains that the gene affected is myostatin.
Myostatin, aka GDF-8, is only expressed in skeletal muscle and not cardiac or smooth muscle: "There are several TGFb s subtypes which are based on their related structure. One such member is called growth and differentiation factors (GDF) and specifically regulates growth and differentiation. GDF-8, also called myostatin, is the skeletal muscle protein associated with the double muscling in mice and cattle."
It only affects striated muscle. Heart muscle is smooth and so is unaffected.
Where did vaccination and antibiotics come from?
It's called research and discovery, since it's is looking at things we know nothing or little about and discovery. Who's to know what we will discover tomorrow? Clearly you know we will not find anything useful, but then what do you or I or the next boffin know?
Nobody knows, that's why it's worth investing in. To find out.
Please, think a little outside of your own confines.
Every biological discovery "may lead to new breakthroughs in aging/cancer/AIDs/impotency treatment", yet so few do.
Maybe why they say may?
At any rate, treatments today are the children of research and as a result we
There is no magic bullet, which people like you believe, that treats and cures all. Even your own words say there are yet so few. Isn't the fact that are are some make it all worthwhile?
Or would you rather take away funding for medical research and pump it into Homeland Defense instead?
...insomuch as it proved a right fiasco in Germany, who now "plans to [scrap the idea and] reintroduce a sticker system for collecting tolls, which it had abandoned last August."
But then again, Americans can succeed where others have failed.
cant they?
Maybe, they plan implementing it like the proposed plans for England and Germany which uses GPS to charge per mile road usage?
The Apple 5300
From wikipedia:The 5300 series is widely considered Apple's worst product of the 1995-1996 time period where the company teetered on the brink of death. In its 5300ce incarnation with a TFT of 800x600 pixels, a 117 MHz PPC, 32 MB on-board RAM and hot-swappable drive bay, the 5300ce was quite ahead of other laptop models at the time, but by far failed to meet the quality standard expected for the price. Many models shipped dead on arrival, and a few 5300's used at Apple actually burst into flames due to problems with then-new Lithium Ion batteries made by Sony (earning the 5300 the nickname "Hindenbook", after the Hindenburg disaster). While no consumer models suffered this fate, Apple was forced to recall the entire product line and delay its availability while they downgraded to proven nickel metal hydride batteries. Apple's much-publicized PowerBook 5300 product placement in the film Mission Impossible turned to disaster when the PowerBooks still hadn't arrived in stores when the movie premiered in theaters. After Apple offered an Extended Repair Program, the series turned into a remarkably attractive machine, but never lost its reputation.
I didn't read anything in the article which says it can amplify DNA like a traditional PCR in minutes. Of course it can only be as fast as the speed of the reaction - 15-30" to efficiently denature a 3kb strand, the speed of the enzyme (~60nt/sec) and of course the primer annealing step - one of the nice things about current PCR (walled tubes) is that the temperature drops to the annealing temperature gradually. If the temperature drop was instantaneous, then you risk mal-annealed primers. At any rate, if you say 30" to allow annealing, and 1 minute for the enzyme to amplify ~3.5kb DNA, then you still have to wait 1 hour for a 30-cycle reaction.
And of course, there are the thermodynamic encumbrances imposed by walled PCR tubes - unless the machine was disposable, I wouldn't like to eliminate the security of x-contamination of using disposable tubes.
I wouldn't even run OS X on a Mac with that little RAM
why is your iCal date saying Jul17 ?
If you don't believe check out these related stories, dating way back
Still, it's new to the US. ZDNet had something similar a few weeks back
Don't overlook the possibility that if the EU's governments move to the right, this case may be damaged.
Just as well then that Spain has a new socialist govt, England isn't voting until late next year, France's centre-right govt, well hates America, and German's Schroeder isn't going anywhere anytime soon.
Oh, wait, you mean the the govts from the new EU members. Yup, those old Soviet Bloc guys have really got some clowt.
Are they trying to increase their 'success' rate on their predictions by quoting other, a little more reliable, news sources?
More importantly, why is Slashdot becoming part of the rumour mill?