I remember the coldest years of the century back in the 1970s. Record low temps, record snowfall. No wonder it was so easy back then to agree with the idea of Global Cooling.
I just wish there would be more science in the discussion rather than "Global Warming is happening, we need to act NOW!!!"
Microsoft is not a PC company, it's a software company. Just like Apple is not a hardware company, it's a software company. No wait, Apple is a hardware company. Errr....
(and those that do have to mask it as something else)
Masking the intents of what research money will be used for? Misappropriating funds? Having a grant to do something and then not working on it? Please. That goes against how grants are given and the whole grant proposal process. He's full of shit.
Heart muscle is also striated. However, the cardiac myocytes are not multi-nucleated and the pattern is more zig-zaggy. Nevertheless, if the cardiac myocytes were not striated, the muscle just wouldn't have enough force to contract and propel blood through the chambers and the peripheral vasculature.
Yes, it should be fairly easy to do a genetic test of the spectrum of ceroid lipofuscinosis related genes by simply extracting DNA from any cell and amplifying the sequence and then sequencing those genes to find the mutation.
It is an interesting therapeutic strategy to inject stem cells foreign to the suffering patient to alleviate the problems with the patient's own DNA. The cause of Batten Disease is a series of mutations in membrane transporters with unknown function. While the mutations affect all body tissues, it is powerfully destructive to neurons and so there is the typical accumulation of autofluorescent pigments (the so-called ceroid lipofuscinosis neuronal).
I think the most important lesson here is that injection of stem cells and the differentiation of those cells and eventual incorporation into the functional neural network is astounding. However, the limits of the therapy are quite evident, since the patient's entire brain suffers from the accumulation of lipofuscin. You'd have to inject enough stem cells to regenerate an entire brain, which is on the scale of billions (could be off by a few factors of ten though....).
As for the cellular and genetic basis for the accumulation of pigments, I'll have to get back to you on that when I conclude my research.:-)
They are actually indeed caused by stress. When your immune system's function is severely inhibited during long-term stress, your body's ability to fight bacterial infection is weakened to the point that H. pylori can easily reside in your stomach and cause the ulcer.
It's too bad that the Nobel Prize was created to reward promising new scientists and to give them enough funding to continue pursuing their research unabated. I know that the society deviates from its original purpose, but the fact still remains that the Nobel Prize selection procedure is about 10-20 years too late to make the impact it was designed for.
You don't get it, it's a rhetorical question. You have to see the forest through the trees, and the point is that you need to consider the ethical questions of each case. But you still haven't.
The promise of adult stem cells has already been demonstrated in this case and in several other treatements including treatment for Parkinson's disease. While embryonic stem cells are purported to have totipotency, this ability is not close to being understood in a therapeutic context. Adult stem cells on the other hand are partially differentiated, are available in every individual, are able to be dedifferentiated, and have already been used effectively in a clinical context. The real propaganda comes from people who are vehemently against ethics and practicality in stem cell debates.
Glial cells are able to help the axonal projections navigate to the desired location. While the axons have been severed in the accident, the glial cells are happy and still working. It is tricky to understand how the process fits into a developmental picture, and how injection of adult stem cells might allow neuroregeneration. Lots of questions, few answers.
This story is not showing up on left-wing pseudo-new sites so far. Considering this is about adult stem cells, it's almost certainly more science than propaganda.
For more information, please consult the peer-reviewed clinical medical research journal "Cytotherapy".
Sorry, I was reponding to your comment about your disagreement with the whitehouse policies, but also to the OP about federal funding. I think my comment got mixed in a jumble.:-)
However, giving them the benefit of the doubt, it is too bad the field of stem cell research in the US has been badly damaged by policies the current Whitehouse administration have put into place.
It's too bad that the OP doesn't understand that umbilical cord blood stem cells are not embryonic stem cells, but rather adult stem cells. But you and he are obviously blinded by politics because you fail to see that the US government is funding this kind of research very heavily.
(BTW, there are ethics involved in research of all kinds, in engineering, in law, in business, etc. You simply do not agree with the idea that ethics should be a part of stem cell research.)
Seriously though, the hurricane bearing down on New Orleans right now should give folks something to think about with respect to global warming.
Yes, indeed, it causes us to think about what it was like before Global Warming, when there were no hurricanes.
Global warming is as much a reality as global cooling, which happens quite frequently in the very short term past hundred years. The earth's climate fluctuates quite rapidly from year to year. CO2 levels fluctuate quite rapidly from year to year. It's a fact of the earth's geological history. What you fail to understand is that knowing global warming and cooling exists is completely different from suggesting that global warming is caused by man's exhaustion of carbon stores.
Slashdot Mirror
I remember the coldest years of the century back in the 1970s. Record low temps, record snowfall. No wonder it was so easy back then to agree with the idea of Global Cooling.
I just wish there would be more science in the discussion rather than "Global Warming is happening, we need to act NOW!!!"
could this bring a future to the Newton platform?
No.
Newton has long been dead.
Microsoft is first and foremost a PC company
Microsoft is not a PC company, it's a software company. Just like Apple is not a hardware company, it's a software company. No wait, Apple is a hardware company. Errr....
Thank you, I'll be here all night!
Indeed you will, it's Friday night afterall.
(and those that do have to mask it as something else)
Masking the intents of what research money will be used for? Misappropriating funds? Having a grant to do something and then not working on it? Please. That goes against how grants are given and the whole grant proposal process. He's full of shit.
You are not a stem cell researcher (they would never refer to themselves as such. The correct and proper term is developmental biologists).
Nice little bullshit story.
Heart muscle is also striated. However, the cardiac myocytes are not multi-nucleated and the pattern is more zig-zaggy. Nevertheless, if the cardiac myocytes were not striated, the muscle just wouldn't have enough force to contract and propel blood through the chambers and the peripheral vasculature.
I'm still waiting on the published research...
This just in, Slashdot proves that it has no shortage to the number of dupes it posts.
My friend said the same thing to me. Small world.
If there ever was a case for computational biology, this is it. :-)
Yes, it should be fairly easy to do a genetic test of the spectrum of ceroid lipofuscinosis related genes by simply extracting DNA from any cell and amplifying the sequence and then sequencing those genes to find the mutation.
It is an interesting therapeutic strategy to inject stem cells foreign to the suffering patient to alleviate the problems with the patient's own DNA. The cause of Batten Disease is a series of mutations in membrane transporters with unknown function. While the mutations affect all body tissues, it is powerfully destructive to neurons and so there is the typical accumulation of autofluorescent pigments (the so-called ceroid lipofuscinosis neuronal).
:-)
I think the most important lesson here is that injection of stem cells and the differentiation of those cells and eventual incorporation into the functional neural network is astounding. However, the limits of the therapy are quite evident, since the patient's entire brain suffers from the accumulation of lipofuscin. You'd have to inject enough stem cells to regenerate an entire brain, which is on the scale of billions (could be off by a few factors of ten though....).
As for the cellular and genetic basis for the accumulation of pigments, I'll have to get back to you on that when I conclude my research.
Somehow I read "feces", and then I thought about Dilbert dropping his shirt pocket materials down the toilet and even his glasses.
They are actually indeed caused by stress. When your immune system's function is severely inhibited during long-term stress, your body's ability to fight bacterial infection is weakened to the point that H. pylori can easily reside in your stomach and cause the ulcer.
So, stress is involved, albeit indirectly.
It's too bad that the Nobel Prize was created to reward promising new scientists and to give them enough funding to continue pursuing their research unabated. I know that the society deviates from its original purpose, but the fact still remains that the Nobel Prize selection procedure is about 10-20 years too late to make the impact it was designed for.
You don't get it, it's a rhetorical question. You have to see the forest through the trees, and the point is that you need to consider the ethical questions of each case. But you still haven't.
Better luck next time.
The promise of adult stem cells has already been demonstrated in this case and in several other treatements including treatment for Parkinson's disease. While embryonic stem cells are purported to have totipotency, this ability is not close to being understood in a therapeutic context. Adult stem cells on the other hand are partially differentiated, are available in every individual, are able to be dedifferentiated, and have already been used effectively in a clinical context. The real propaganda comes from people who are vehemently against ethics and practicality in stem cell debates.
Glial cells are able to help the axonal projections navigate to the desired location. While the axons have been severed in the accident, the glial cells are happy and still working. It is tricky to understand how the process fits into a developmental picture, and how injection of adult stem cells might allow neuroregeneration. Lots of questions, few answers.
This story is not showing up on left-wing pseudo-new sites so far. Considering this is about adult stem cells, it's almost certainly more science than propaganda.
For more information, please consult the peer-reviewed clinical medical research journal "Cytotherapy".
No.
Sorry, I was reponding to your comment about your disagreement with the whitehouse policies, but also to the OP about federal funding. I think my comment got mixed in a jumble. :-)
However, giving them the benefit of the doubt, it is too bad the field of stem cell research in the US has been badly damaged by policies the current Whitehouse administration have put into place.
It's too bad that the OP doesn't understand that umbilical cord blood stem cells are not embryonic stem cells, but rather adult stem cells. But you and he are obviously blinded by politics because you fail to see that the US government is funding this kind of research very heavily.
(BTW, there are ethics involved in research of all kinds, in engineering, in law, in business, etc. You simply do not agree with the idea that ethics should be a part of stem cell research.)
Google Blog link.
Seriously though, the hurricane bearing down on New Orleans right now should give folks something to think about with respect to global warming.
Yes, indeed, it causes us to think about what it was like before Global Warming, when there were no hurricanes.
Global warming is as much a reality as global cooling, which happens quite frequently in the very short term past hundred years. The earth's climate fluctuates quite rapidly from year to year. CO2 levels fluctuate quite rapidly from year to year. It's a fact of the earth's geological history. What you fail to understand is that knowing global warming and cooling exists is completely different from suggesting that global warming is caused by man's exhaustion of carbon stores.
Now they just need to be mounted on those damn sharks.