You might want to write a story exploring the potential of AI and robotics. Or nuclear fusion power. Or asteroid mining. Or molecular manufacturing. Or life extension. All good topics. Now try to write a novel where *all* of those scenarios have become real and are interacting with one another. Oops... That's going to be really hard to pull off without ending up in a muddled mess, and it's also going to be hard to explore each of those ideas in the depth it deserves. (Especially if you also have, you know... characters, and a plot, and so forth!)
You might wanna check out the The Quantum Thief and its sequels. It covers everything you just mentioned and much more...
I think the new wave of Windows 7 and Android tablets will show that in short order
Why do you think companies are investing into tablets all of a sudden after long years of indifference? Here is a hint, it has to do with a company who singlehandedly changed the smartphone paradigm for the betterment of everyone and introduced a new wave of healthy competition.
everyone who actually wanted a real tablet computer
No one cared about tablets before iPad. While I hate the heavy handed control Apple has over iPad and won't be buying one, I WILL buy a comparable tablet with Android that has a competent multi-touch interface.
THis paper is striking because it again underlines that evolution occurs by chance (genetic drift) in many cases and humanity is on the verge of gripping evolution from the horns. Here is a perfectly fine gene, inactivated by a premature termination codon mutation that occurred after human lineage diverged from the lineage we share with orangutans, lesser apes, and old world monkeys. Why? because there was no significant selective pressure against it and probably trough some chance event (think founder effect) we as a species lost this gene. Now trough paleogenetics we awaken a 7 million old gene from pseudogene hell! It makes me excited for my chosen profession again (PhD is hard and you need all the motivation you can get)
It has the option to run on a silent (don't know how silent) jet fuel powered generator for 8 hours a day for three days. That sounds to me like a workable solution for the (hypothetical) heavy weapons guy in assault squads in the field.
Induced pluripotent cells (which they generated here) are actually shown to be able to differentiate into many many cell types. Indeed the next step is to test their properties in more detail but literature suggests it will work with a high probability. Here directly from wikipedia:
Pluripotency: iPSCs were capable of differentiation in a fashion similar to ESCs into fully differentiated tissues.
* Neural Differentiation: iPSCs were differentiated into neurons, expressing βIII-tubulin, tyrosine hydroxylase, AADC, DAT, ChAT, LMX1B, and MAP2. The presence of catecholamine-associated enzymes may indicate that iPSCs, like hESCs, may be differentiable into dopaminergic neurons. Stem cell-associated genes were downregulated after differentiation.
* Cardiac Differentiation: iPSCs were differentiated into cardiomyocytes that spontaneously began beating. Cardiomyocytes expressed TnTc, MEF2C, MYL2A, MYHCβ, and NKX2.5. Stem cell-associated genes were downregulated after differentiation.
* Teratoma Formation: iPSCs injected into immunodeficient mice spontaneously formed teratomas after nine weeks. Teratomas are tumors of multiple lineages containing tissue derived from the three germ layers endoderm, mesoderm and ectoderm; this is unlike other tumors, which typically are of only one cell type. Teratoma formation is a landmark test for pluripotency.
* Embryoid Body: hESCs in culture spontaneously form ball-like embryo-like structures termed "embryoid bodies", which consist of a core of mitotically active and differentiating hESCs and a periphery of fully differentiated cells from all three germ layers. iPSCs also form embryoid bodies and have peripheral differentiated cells.
* Blastocyst Injection: hESCs naturally reside within the inner cell mass (embryoblast) of blastocysts, and in the embryoblast, differentiate into the embryo while the blastocyst's shell (trophoblast) differentiates into extraembryonic tissues. The hollow trophoblast is unable to form a living embryo, and thus it is necessary for the embryonic stem cells within the embryoblast to differentiate and form the embryo. iPSCs were injected by micropipette into a trophoblast, and the blastocyst was transferred to recipient females. Chimeric living mouse pups were created: mice with iPSC derivatives incorporated all across their bodies with 10%-90& chimerism.
Nod32 also caught it with
HTTP filter archive http://getthefacts.on.zoy.org/ probably a variant of HTML/Exploit.DialogArg.A trojan connection terminated Threat was detected upon access to web by the application: firefox.exe.
You didn't even RTFA. Here I past the relevant passage:
FROM ROAD TO AIR IN THE SKYCAR
The driver unpacks the parafoil wing from the boot and manually deploys it from the rear of the car. He switches the transmission from road mode, which drives the wheels, to flight mode, which powers the rear fan
The fan's thrust pushes the car forward, providing lift for the wing as the car reaches 35mph - takeoff speed. Once airborne, pedals in the footwell steer the Skycar by pulling cables that change the wing's shape
The Skycar has a flying range of about 180 miles. If the wing is damaged or collapses, the pilot can fire a roof-mounted emergency parachute that allows the car to float safely back to earth
Even that resolution can be beneficial. I am thingking they are aiming for big complexes in functional interactions with other proteins. Say observing a nucleosome in actin? or what exactly is going on during exocytosis? You might distinguish familiar players by their rough shape and this might be enough to say your protein complex of interest is involved in exocytosis.Couple this with transmission electron microscopy (which has 2nm resolution) it might be powerful indeed.
If this methods becomes popular, taking down big torrent tracker sites would be even more meaningless and and cost-ineffective. I predict MAFIAA and its ilk will go after individual peers with renewed vigor and pour even more money into lobbying sorry bribing lawmakers to introduce even more ridiculous laws and shift the responsibility of enforcing these onto ISPs.
The procedure is still untested in animal experiments, meaning they don't know if transplanted it will work at all but this is certainly encouraging. Best of luck to Dr. Yacoub and his team.
Also I couldn't find a link to the paper by Dr. Yacoub which should have been
here
He in all probability knows what you just posted about but he has to stay in his position as a fighter against violence in games and gain political support no matter how bullshit his arguments are. Politicians rarely speak about what they believe in, it's just a big power game with sources you exploit for votes and support.
If you have some kind of condition that makes you probable to cardiac arrest under high stress conditions or low-g environments (astronauts?) and there is genetic screen process available for this shouldn't these institutions be allowed to test candidates for these? After all, they do eliminate people based on physical fitness, eyesight etc. which are all heavily influenced by genetics.
According to the article, Vitamin D deficiency causes whole other nasty types of cancers of body like colon, breast etc. Skin cancer has a much better prognosis then the cancer of the inner body.
Also, we evolved in Africa. Surely evolution found a balance between cancer of skin and Vitamin D synthesis? Also, color of skin is basically the answer of natural selection to the latitude your ancestors migrated to.
Here is a choice quote:
A BLAST alignment and similarity search (23) of the five T. rex peptides from collagen {alpha}1t1 as a group against the all-taxa protein database showed 58% sequence identity to chicken, followed by frog (51% identity) and newt (51% identity). The small group of peptide sequence data reported here support phylogenetic hypotheses suggesting that T. rex is most closely related to birds among living organisms whose collagen sequence is present in protein databases (24-26). This article documents previous research: http://www.sciencemag.org/cgi/content/abstract/316 /5822/277 Analyses of Soft Tissue from Tyrannosaurus rex Suggest the Presence of Protein
The ability to read papers online was the best thing that happened for the progress of science since the invention of since automatic printing was invented. Fuck you greedy people trying to impede the free dissemination of information for lining their pockets.
I apologize, these people get to me.
My friend, consider this word "Funding".
I need money. I look at the funding agencies. I don't see many that pay for "basic science", so I put words like "Y might ultimately result in curing X" so I can get money to research Y, Y being whatever I fancy knowing about more.
Also, look at the the last sentences of Discussion part of any biomedical paper. They are often about therapeutic possibilities of that research. Sadly, we need to justify why we spend their money on basic research just to satisfy our intellectual urges.
Slashdot Mirror
You might want to write a story exploring the potential of AI and robotics. Or nuclear fusion power. Or asteroid mining. Or molecular manufacturing. Or life extension. All good topics. Now try to write a novel where *all* of those scenarios have become real and are interacting with one another. Oops... That's going to be really hard to pull off without ending up in a muddled mess, and it's also going to be hard to explore each of those ideas in the depth it deserves. (Especially if you also have, you know... characters, and a plot, and so forth!)
You might wanna check out the The Quantum Thief and its sequels. It covers everything you just mentioned and much more...
That's linguistic ownage.
Why do you think companies are investing into tablets all of a sudden after long years of indifference? Here is a hint, it has to do with a company who singlehandedly changed the smartphone paradigm for the betterment of everyone and introduced a new wave of healthy competition.
No one cared about tablets before iPad. While I hate the heavy handed control Apple has over iPad and won't be buying one, I WILL buy a comparable tablet with Android that has a competent multi-touch interface.
They later commented that that was a mistake and matte screens will be the way to go.
THis paper is striking because it again underlines that evolution occurs by chance (genetic drift) in many cases and humanity is on the verge of gripping evolution from the horns. Here is a perfectly fine gene, inactivated by a premature termination codon mutation that occurred after human lineage diverged from the lineage we share with orangutans, lesser apes, and old world monkeys. Why? because there was no significant selective pressure against it and probably trough some chance event (think founder effect) we as a species lost this gene. Now trough paleogenetics we awaken a 7 million old gene from pseudogene hell! It makes me excited for my chosen profession again (PhD is hard and you need all the motivation you can get)
It has the option to run on a silent (don't know how silent) jet fuel powered generator for 8 hours a day for three days. That sounds to me like a workable solution for the (hypothetical) heavy weapons guy in assault squads in the field.
Induced pluripotent cells (which they generated here) are actually shown to be able to differentiate into many many cell types. Indeed the next step is to test their properties in more detail but literature suggests it will work with a high probability. Here directly from wikipedia:
Pluripotency: iPSCs were capable of differentiation in a fashion similar to ESCs into fully differentiated tissues.
* Neural Differentiation: iPSCs were differentiated into neurons, expressing βIII-tubulin, tyrosine hydroxylase, AADC, DAT, ChAT, LMX1B, and MAP2. The presence of catecholamine-associated enzymes may indicate that iPSCs, like hESCs, may be differentiable into dopaminergic neurons. Stem cell-associated genes were downregulated after differentiation.
* Cardiac Differentiation: iPSCs were differentiated into cardiomyocytes that spontaneously began beating. Cardiomyocytes expressed TnTc, MEF2C, MYL2A, MYHCβ, and NKX2.5. Stem cell-associated genes were downregulated after differentiation.
* Teratoma Formation: iPSCs injected into immunodeficient mice spontaneously formed teratomas after nine weeks. Teratomas are tumors of multiple lineages containing tissue derived from the three germ layers endoderm, mesoderm and ectoderm; this is unlike other tumors, which typically are of only one cell type. Teratoma formation is a landmark test for pluripotency.
* Embryoid Body: hESCs in culture spontaneously form ball-like embryo-like structures termed "embryoid bodies", which consist of a core of mitotically active and differentiating hESCs and a periphery of fully differentiated cells from all three germ layers. iPSCs also form embryoid bodies and have peripheral differentiated cells.
* Blastocyst Injection: hESCs naturally reside within the inner cell mass (embryoblast) of blastocysts, and in the embryoblast, differentiate into the embryo while the blastocyst's shell (trophoblast) differentiates into extraembryonic tissues. The hollow trophoblast is unable to form a living embryo, and thus it is necessary for the embryonic stem cells within the embryoblast to differentiate and form the embryo. iPSCs were injected by micropipette into a trophoblast, and the blastocyst was transferred to recipient females. Chimeric living mouse pups were created: mice with iPSC derivatives incorporated all across their bodies with 10%-90& chimerism.
Nod32 also caught it with
HTTP filter archive http://getthefacts.on.zoy.org/ probably a variant of HTML/Exploit.DialogArg.A trojan connection terminated Threat was detected upon access to web by the application: firefox.exe.
You didn't even RTFA. Here I past the relevant passage:
FROM ROAD TO AIR IN THE SKYCAR
The driver unpacks the parafoil wing from the boot and manually deploys it from the rear of the car. He switches the transmission from road mode, which drives the wheels, to flight mode, which powers the rear fan
The fan's thrust pushes the car forward, providing lift for the wing as the car reaches 35mph - takeoff speed. Once airborne, pedals in the footwell steer the Skycar by pulling cables that change the wing's shape
The Skycar has a flying range of about 180 miles. If the wing is damaged or collapses, the pilot can fire a roof-mounted emergency parachute that allows the car to float safely back to earth
He made it.
Even that resolution can be beneficial. I am thingking they are aiming for big complexes in functional interactions with other proteins. Say observing a nucleosome in actin? or what exactly is going on during exocytosis? You might distinguish familiar players by their rough shape and this might be enough to say your protein complex of interest is involved in exocytosis.Couple this with transmission electron microscopy (which has 2nm resolution) it might be powerful indeed.
If this methods becomes popular, taking down big torrent tracker sites would be even more meaningless and and cost-ineffective. I predict MAFIAA and its ilk will go after individual peers with renewed vigor and pour even more money into lobbying sorry bribing lawmakers to introduce even more ridiculous laws and shift the responsibility of enforcing these onto ISPs.
come on it was just the bait.
here is the pubmed citation and abstract link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&uid=6668953&cmd=showdetailview/
Also I couldn't find a link to the paper by Dr. Yacoub which should have been here
You don't understand politicians, do you?
He in all probability knows what you just posted about but he has to stay in his position as a fighter against violence in games and gain political support no matter how bullshit his arguments are. Politicians rarely speak about what they believe in, it's just a big power game with sources you exploit for votes and support.
Indeed, now make a color version of this:
If you have some kind of condition that makes you probable to cardiac arrest under high stress conditions or low-g environments (astronauts?) and there is genetic screen process available for this shouldn't these institutions be allowed to test candidates for these? After all, they do eliminate people based on physical fitness, eyesight etc. which are all heavily influenced by genetics.
According to the article, Vitamin D deficiency causes whole other nasty types of cancers of body like colon, breast etc. Skin cancer has a much better prognosis then the cancer of the inner body.
Also, we evolved in Africa. Surely evolution found a balance between cancer of skin and Vitamin D synthesis? Also, color of skin is basically the answer of natural selection to the latitude your ancestors migrated to.
Get naked and get out! you know.. for Vitamin D synthesis.
Atatürk's Reforms.
It is not referenced in this link but he basically scrapped ottoman measurement systems and introduced metric system.
Here is it:
http://www.sciencemag.org/cgi/content/full/316/58
Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry
Here is a choice quote: A BLAST alignment and similarity search (23) of the five T. rex peptides from collagen {alpha}1t1 as a group against the all-taxa protein database showed 58% sequence identity to chicken, followed by frog (51% identity) and newt (51% identity). The small group of peptide sequence data reported here support phylogenetic hypotheses suggesting that T. rex is most closely related to birds among living organisms whose collagen sequence is present in protein databases (24-26). This article documents previous research:
http://www.sciencemag.org/cgi/content/abstract/31
Analyses of Soft Tissue from Tyrannosaurus rex Suggest the Presence of Protein
The ability to read papers online was the best thing that happened for the progress of science since the invention of since automatic printing was invented. Fuck you greedy people trying to impede the free dissemination of information for lining their pockets. I apologize, these people get to me.
My friend, consider this word "Funding". I need money. I look at the funding agencies. I don't see many that pay for "basic science", so I put words like "Y might ultimately result in curing X" so I can get money to research Y, Y being whatever I fancy knowing about more. Also, look at the the last sentences of Discussion part of any biomedical paper. They are often about therapeutic possibilities of that research. Sadly, we need to justify why we spend their money on basic research just to satisfy our intellectual urges.
and this is only the first week!