The Ion Proton Sequencer uses analysis software called Ion Reporter to analyze the data of a single genome on a single server. This speeds up the process considerably and removes the IT-related bottlenecks
Genius! A cluster of computers is an obvious bottleneck and they have made the step of getting a single server to do all the work. I hope they have a patent on that idea.
However, the most important factor in reducing the sequencing speed so dramatically is the introduction of the next generation of Ion Torrent semiconductor chip technology.
Oh. Right. So this is really just using _better_ hardware to do the job.
I may have to stand corrected myself... it may live in the lungs but can be latent and not come out, only developing later. I also assume that my idea is so obvious that if it isn't being done already there is obviously a good reason for it... the guys who fight these diseases aren't stupid.
You might be right about the IQ scores of the homeless (although I would expect a slightly higher distribution at the higher and lower ends of the curve and less in the middle) but to extrapolate those IQ scores into an ability to hold a job and contribute to society is possibly flawed. But I agree with the rest of what you said - there are far worse ways to spend $6bn than helping homeless people, assuming it's done properly, and even if you only got jobs and homes for half of those people it's still money well spent.
WTH? If the drug kills people then it's not an antibiotic, it's just a poison.
Some of our best medicines are poisons, including to the host. You just have to balance the dose so that it kills the pathogen without quite killing the host. A lot of anti-fungal medications are highly toxic to various organs in the body. And chemotherapy revolves around the idea that the cancer cells are more susceptible to the poison than the rest of the body.
Any vaccine will ruin a test for antibodies. What we need is a direct test for the bacteria.
It lives in the lungs... FOR GOD SAKES!
It obviously doesn't stay there though otherwise it could never spread to another person... so maybe a paper bag treated with some reactive agent that the patient can cough into would be the sort of test the GP was thinking of.
So are all homeless people geniuses or have they just stumbled across one homeless person who happens to have a brilliant mind and extrapolated that finding to all homeless people?
Who's saying they are blowing it off? From what I understand, they are aware of the problem, have isolated it's cause, and deemed it non critical. And I do trust Airbus far enough that they do not want to see one of these planes fall out of the sky.
The cracks are for course troubling in such a young aircraft, but blowing issues out of proportion is about as bad as ignoring them.
Agree. The alternative is that the cracks really are critical but Airbus are playing down the problem because they've decided that having an accident, forcing them to ground the rest of the fleet anyway, having to pay out billions in damages and fines, and completely destroying their reputation, is a better option than grounding the fleet now and repairing the aircraft.
Before I listen to anyone's opinion that these cracks are more of a problem than Airbus say they are, i'd want to see some qualifications in metallurgy or similar discipline.
I can't find the link but I thought the existing plants were already past their expected lifespans, but were still operating because the authorities deemed them safe enough to continue operating. So how does this new wordplay change anything?
The concept of genetic engineering is not scary because of the "risk" of GMO fields infecting natural genetics, but because of the few psychopaths who would like to use such technology to "eliminate disease." Who's to say a "disease" is not the first step of the next stage of evolution?
The cool thing here is that, according to the article at least, they aren't actually modifying genes anywhere, just introducing a hormone to activate genes on a one-off basis. Take away the hormone and everything is back to normal.
The next step, correcting the evolved corruption in the DNA that prevents the hive from releasing the hormone, wouldn't be too hard though.
The brilliance of many people I've met with ADHD and various levels of autism disorders are a key example -- they're not SUCCESSFUL adaptations yet, but I believe they're the beginnings of an evolution of a greater intelligence than the typical modern human.
There are a large number of stupid people with ADHD and autism spectrum disorders too... autism doesn't automatically equal increased intelligence, although I suspect that ASD is a fairly general term for a number of things that appear on the surface to be similar but have vastly different underlying causes.
Is anyone on record of having died from a dirty keyboard? I never heard of it. Germs are rarely dangreous. What about when you walk out your door into the coutryside, no one ever sterilises that. If we follow the logic behind this, we should sterilise that to.
"died from a dirty telephone" only gives HHGTTG references. Even "died from a dirty toilet" scores only 6 results, and most of those seem to be people asking if anyone died that way.
I guess germs aren't that dangerous after all... or they are so dangerous that nobody lived to blog about it;)
Unless you happen to be using a public keyboard, these are going to be germs from YOUR body. If they were going to be a problem, then they already would be.
Stick your finger in your bum, wiggle it around real good, then stick it in your mouth. They are YOUR germs from YOUR body, but that still doesn't mean they won't make you sick.
Washing your OWN hands would be a lot more effective.
One not-yet-discredited (I think) theory is that some auto-immune diseases are caused (or triggered) by the allergen getting somewhere it shouldn't, causing an exaggerated immune response. One my my kids has coeliac disease, and there is some speculation that this is triggered in some cases by repeated exposure to other parts of the body by gluten, one of those being repeated handwashing cracking and damaging the skin on the hands allowing gluten proteins to enter (as well as by wheat based products in the soap/hand wash itself).
OTOH, not washing your hands at all is hardly a good way to overcome that:)
It's fine as long as you use it properly. I use it for IIS logfiles. I want to keep the logfiles but rarely actually access them, and they are append only, and they are plain text. Very high compression at a very small loss of performance.
Compressing binary data in your working set is, as you point out, probably a bad idea, but as long as you don't do anything stupid you shouldn't have any problems.
It would be nice if you could also see the feedback weighted by the sell price. A reseller could sell hundreds of $2 items legitimately but run a scam for high value items selling less frequently and still maintain a fairly good feedback balance.
I thought the point of money laundering was to conceal the source of or legitimize undisclosed money?
If I buy a fake violin for $1,000,000 the police are still going to say "Whoa whoa whoa there, where the hell did you get a million dollars?"
The buyer is anonymous and picked up the violin in person and paid cash, and could be a made up entity. The police are certainly never going to find them to ask where they got the million dollars from.
I thought they were putting those spider genes into goats years ago to have them spin the super silk instead of milk. I guess that went nowhere.. I would have liked to seen some goat-spider beast running around...
I think they switched to pigs when the Simpsons movie came out. Sure, pigs produce nowhere near as much milk, and they've had to throw out years of research with goat DNA, but a spiderpig is just so much cooler.
It is not perjury to suggest an alternate explanation to the evidence, AFAIK. Or at least for the defendant's lawyer to do so.
defendant lawyer: The GPS only proves the location of the vehicle, not who was driving it at the time. prosecution lawyer: Mr Defendant, were you driving the car at the time? defendant: I... errr... um...
If the defendant was driving at the time and is asked the question directly, lying about it is still perjury no matter how many alternate possible explanations might exist. They could maybe weasel their way out of it with a "I don't recall" though, assuming that other people driving the car was a regular event.
They are already doing this in Melbourne (Australia) for regular parking spots. Some spots have sensors which detect when a vehicle enters and leaves the spot, and car-mounted camera's drive around checking plates as well. It wouldn't be too hard to extend that to cars known to have permits or not.
I'm not sure though, even in Australia where I live, if the permits are linked to the vehicle or the person. The latter would make more sense (eg if you're helping a friend out by taking them to the shops in your car) but then it isn't possible to automatically process via camera (tags in Australia are mounted on the front windscreen which isn't normally visible from the road depending on how the car is parked).
The thing that really bugs me is the parents at my kids school who park in the disabled spots even when they don't have the disabled child/person with them and aren't picking them up or dropping them off. These are the same parents that will yell and scream at others if they dare use those spots when they shouldn't. Grrr.
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I hate to break it to you, but he has Parkinson's, not MS.
when all you have is a hammer, everything looks like a skull.
The Ion Proton Sequencer uses analysis software called Ion Reporter to analyze the data of a single genome on a single server. This speeds up the process considerably and removes the IT-related bottlenecks
Genius! A cluster of computers is an obvious bottleneck and they have made the step of getting a single server to do all the work. I hope they have a patent on that idea.
However, the most important factor in reducing the sequencing speed so dramatically is the introduction of the next generation of Ion Torrent semiconductor chip technology.
Oh. Right. So this is really just using _better_ hardware to do the job.
I may have to stand corrected myself... it may live in the lungs but can be latent and not come out, only developing later. I also assume that my idea is so obvious that if it isn't being done already there is obviously a good reason for it... the guys who fight these diseases aren't stupid.
You might be right about the IQ scores of the homeless (although I would expect a slightly higher distribution at the higher and lower ends of the curve and less in the middle) but to extrapolate those IQ scores into an ability to hold a job and contribute to society is possibly flawed. But I agree with the rest of what you said - there are far worse ways to spend $6bn than helping homeless people, assuming it's done properly, and even if you only got jobs and homes for half of those people it's still money well spent.
Somewhere in the dawn of Google someone wrote "Don't be evil" on a whiteboard. It's just possible that the "Don't" might be getting a little faded...
WTH? If the drug kills people then it's not an antibiotic, it's just a poison.
Some of our best medicines are poisons, including to the host. You just have to balance the dose so that it kills the pathogen without quite killing the host. A lot of anti-fungal medications are highly toxic to various organs in the body. And chemotherapy revolves around the idea that the cancer cells are more susceptible to the poison than the rest of the body.
Any vaccine will ruin a test for antibodies. What we need is a direct test for the bacteria.
It lives in the lungs... FOR GOD SAKES!
It obviously doesn't stay there though otherwise it could never spread to another person... so maybe a paper bag treated with some reactive agent that the patient can cough into would be the sort of test the GP was thinking of.
So are all homeless people geniuses or have they just stumbled across one homeless person who happens to have a brilliant mind and extrapolated that finding to all homeless people?
I was going to just plant some trees, but covering my property in plastic seems like a much better idea!
If the plastic was green and tree shaped, then everybody wins!
I read that as "Wifi Free" at first and thought the "wifi causes cancer" nutjobs had won...
But, but ... Wifi causes cancer! Or does it not ? ;-)
Probably at about the same rate as breathing in and out causes cancer.
I read that as "Wifi Free" at first and thought the "wifi causes cancer" nutjobs had won...
Who's saying they are blowing it off?
From what I understand, they are aware of the problem, have isolated it's cause, and deemed it non critical. And I do trust Airbus far enough that they do not want to see one of these planes fall out of the sky.
The cracks are for course troubling in such a young aircraft, but blowing issues out of proportion is about as bad as ignoring them.
Agree. The alternative is that the cracks really are critical but Airbus are playing down the problem because they've decided that having an accident, forcing them to ground the rest of the fleet anyway, having to pay out billions in damages and fines, and completely destroying their reputation, is a better option than grounding the fleet now and repairing the aircraft.
Before I listen to anyone's opinion that these cracks are more of a problem than Airbus say they are, i'd want to see some qualifications in metallurgy or similar discipline.
I can't find the link but I thought the existing plants were already past their expected lifespans, but were still operating because the authorities deemed them safe enough to continue operating. So how does this new wordplay change anything?
parents who say "I want my baby to be special."
If we get enough parents who read superhero comics in their childhood, we'll end up with more diversity than we ever imagined...
"Thinking of having a baby? We have a special on the Spiderman package this month!"
"Studies have shown that our Catwoman genepack will help your child be more successful"
The concept of genetic engineering is not scary because of the "risk" of GMO fields infecting natural genetics, but because of the few psychopaths who would like to use such technology to "eliminate disease." Who's to say a "disease" is not the first step of the next stage of evolution?
The cool thing here is that, according to the article at least, they aren't actually modifying genes anywhere, just introducing a hormone to activate genes on a one-off basis. Take away the hormone and everything is back to normal.
The next step, correcting the evolved corruption in the DNA that prevents the hive from releasing the hormone, wouldn't be too hard though.
The brilliance of many people I've met with ADHD and various levels of autism disorders are a key example -- they're not SUCCESSFUL adaptations yet, but I believe they're the beginnings of an evolution of a greater intelligence than the typical modern human.
There are a large number of stupid people with ADHD and autism spectrum disorders too... autism doesn't automatically equal increased intelligence, although I suspect that ASD is a fairly general term for a number of things that appear on the surface to be similar but have vastly different underlying causes.
Actually you're fairly unlikely to get sick from your own feces, that doesn't make it less gross though.
Try putting your contact lens in your mouth then...
Is anyone on record of having died from a dirty keyboard? I never heard of it. Germs are rarely dangreous. What about when you walk out your door into the coutryside, no one ever sterilises that. If we follow the logic behind this, we should sterilise that to.
google agrees with you.
"died from a dirty telephone" only gives HHGTTG references. Even "died from a dirty toilet" scores only 6 results, and most of those seem to be people asking if anyone died that way.
I guess germs aren't that dangerous after all... or they are so dangerous that nobody lived to blog about it ;)
Unless you happen to be using a public keyboard, these are going to be germs from YOUR body. If they were going to be a problem, then they already would be.
Stick your finger in your bum, wiggle it around real good, then stick it in your mouth. They are YOUR germs from YOUR body, but that still doesn't mean they won't make you sick.
Washing your OWN hands would be a lot more effective.
One not-yet-discredited (I think) theory is that some auto-immune diseases are caused (or triggered) by the allergen getting somewhere it shouldn't, causing an exaggerated immune response. One my my kids has coeliac disease, and there is some speculation that this is triggered in some cases by repeated exposure to other parts of the body by gluten, one of those being repeated handwashing cracking and damaging the skin on the hands allowing gluten proteins to enter (as well as by wheat based products in the soap/hand wash itself).
OTOH, not washing your hands at all is hardly a good way to overcome that :)
Alcohol works very well, that is why there is little risk of bacteria developing a resistance to it.
Even the yeast that make the stuff actually get killed by it.
NTFSs file compression actually rather sucks.
It's fine as long as you use it properly. I use it for IIS logfiles. I want to keep the logfiles but rarely actually access them, and they are append only, and they are plain text. Very high compression at a very small loss of performance.
Compressing binary data in your working set is, as you point out, probably a bad idea, but as long as you don't do anything stupid you shouldn't have any problems.
It would be nice if you could also see the feedback weighted by the sell price. A reseller could sell hundreds of $2 items legitimately but run a scam for high value items selling less frequently and still maintain a fairly good feedback balance.
I thought the point of money laundering was to conceal the source of or legitimize undisclosed money?
If I buy a fake violin for $1,000,000 the police are still going to say "Whoa whoa whoa there, where the hell did you get a million dollars?"
The buyer is anonymous and picked up the violin in person and paid cash, and could be a made up entity. The police are certainly never going to find them to ask where they got the million dollars from.
I thought they were putting those spider genes into goats years ago to have them spin the super silk instead of milk. I guess that went nowhere.. I would have liked to seen some goat-spider beast running around...
I think they switched to pigs when the Simpsons movie came out. Sure, pigs produce nowhere near as much milk, and they've had to throw out years of research with goat DNA, but a spiderpig is just so much cooler.
It is not perjury to suggest an alternate explanation to the evidence, AFAIK. Or at least for the defendant's lawyer to do so.
defendant lawyer: The GPS only proves the location of the vehicle, not who was driving it at the time.
prosecution lawyer: Mr Defendant, were you driving the car at the time?
defendant: I... errr... um...
If the defendant was driving at the time and is asked the question directly, lying about it is still perjury no matter how many alternate possible explanations might exist. They could maybe weasel their way out of it with a "I don't recall" though, assuming that other people driving the car was a regular event.
They are already doing this in Melbourne (Australia) for regular parking spots. Some spots have sensors which detect when a vehicle enters and leaves the spot, and car-mounted camera's drive around checking plates as well. It wouldn't be too hard to extend that to cars known to have permits or not.
I'm not sure though, even in Australia where I live, if the permits are linked to the vehicle or the person. The latter would make more sense (eg if you're helping a friend out by taking them to the shops in your car) but then it isn't possible to automatically process via camera (tags in Australia are mounted on the front windscreen which isn't normally visible from the road depending on how the car is parked).
The thing that really bugs me is the parents at my kids school who park in the disabled spots even when they don't have the disabled child/person with them and aren't picking them up or dropping them off. These are the same parents that will yell and scream at others if they dare use those spots when they shouldn't. Grrr.