He needs to release it as open source, and secretly patent the algorithm (or even patient the basic concept as Amazon and Apple have done). Wait until a better functioning company with a smarter owner starts using your code. Allow it to get really widespread and allow your competitor to get really successful with great marketing and hard work. Let them broker the deals, let them do the hard sell, let them spend their capital promoting it.
You should use "an" as the article if the next word begins with a vowel sound. So we say "a European" (pronounced you-row-pean), "a universal serial bus", "a U-boat", "a yellow banana". We say "an apple", "an honourable discharge", and "an yttrium semiconductor" (pronounced ittrium),
So the rule is based on the sound and how things flow, not the actual letter of the alphabet used.
You're a non-elected "government" full of overpaid ex- and failed politicians, and you're still trying to scam more money while Europe burns. Stop with the heavy intervention, you make me sick! Hopefully this EU thing is not going to last - Europe doesn't need dictators.
This gene produces a protein called alpha-actinin-3 that is only turned on in fast-twitch muscle fibers (the kind used for power events like sprinting or weightlifting). The protein forms part of the contractile machinery in muscle cells, where it is thought to play both structural and signalling roles.
The T version of the SNP in this gene prevents the full protein from being made. People with two copies of the T version thus have a total lack of alpha-actinin-3 in their fast-twitch muscle fibers. Those with the CT genotype have one functional copy of the gene and can still make the protein.
Surprisingly, a complete lack of the alpha-actinin-3 protein doesn't seem to cause any type of disease. This is probably because another closely related protein can step in for alpha-actinin-3 in people without a functional copy. The substitute protein likely does not perform its job as well as alpha-actinin-3, resulting in worse performance in power exercises.
Despite lack of a disease outcome, researchers wondered if the absence of alpha-actinin-3 might have an effect on athletic performance. Studies of elite athletes in Australia and Finland showed that power athletes—those whose performance depends on fast-twitch muscle fibers—were much more likely to have at least one working copy of the gene than non-athletes. In one study of Olympic power athletes (i.e., the best of the best), all had at least one working copy. Similar results were found in a study of Spanish professional soccer players.
But does alpha-actinin-3 make a difference for non-athletes? In fact, it does.
One study looked at a group of Greek teenagers who had been tested for a variety of fitness measures related to power and endurance sports. In this group, ACTN3 genotype had no effect on the girls, but boys with the TT genotype were significantly slower in a 40 m sprint. Interestingly, running was the only power event that the different versions of ACTN3 seemed to affect. For activities like throwing a basketball or jumping into the air, performance was unaffected by genotype.
Another study looked at arm strength in a group of people before and after 12 weeks of strength training. ACTN3 genotype appeared to have no effect in men, but women with the TT genotype had lower strength at the beginning of the study. After the training program women with the TT genotype—those without a working copy of alpha-actinin-3—had made greater gains than the women with at least one functioning copy. This was true in both European and Asian women.
Scientists aren't really sure why having alpha-actinin-3 would improve power performance. One theory is that the protein prevents damage in fast-twitch muscle fibers. The group who conducted the study of Greek teenagers thinks this explains why only running and not other power activities were affected by a lack of alpha-actinin-3. Running involves repeated use of the muscles, while jumping only uses muscles once: damage is not an issue.
The scientists who saw that women with the TT genotype were able to build up more strength than other women also think alpha-actinin-3 protects muscle fibers from damage. Muscle damage is what stimulates muscles to adapt and become stronger. Those with the TT genotype lack the protection against damage that alpha-actinin-3 normally provides, thus allowing a greater gain in strength.
Alpha-actinin-3 may also affect athletic performance by virtue of its effects on oxygen usage in muscle. Two studies (one in mice and one in humans) have shown that fast-twtich muscle fibers that lack functional copies of ACTN3 use more oxygen than those with at least one working copy. This type of metabolism might slow them down. Mice studies have also shown that these altered fibers are weaker and smaller than fibers containing alpha-actinin-3, but they are more efficient an resistant to fatigue—a situation that is better suited to endurance sports than sprinting.
Well, not really a scam, but it's incredibly overpriced and gives you no useful information. That gene has very little effect outside of maybe the elite of the elite. Your body shape contributes much much more to your "ideal" sport. (More important is what the kid enjoys.)
For $200, you can test 500,000 SNPs with 23andMe, get much more useful health info plus ancestry information.
My result from 23andMe: rs1815739:CT "One working copy of alpha-actinin-3 in fast-twitch muscle fiber. Many world-class sprinters and some endurance athletes have this genotype."
I've actually seen a number of companies that test for a few SNPs, charging $hundreds and making misleading claims. I can't say for sure if they're fly-by-nighters out to make a buck, but there are much cheaper ways of getting more information.
I'm not American, but those occupy protests aren't middle anything. They're just protesters and hipsters, each with their own agendas, who sit and masturbate about how they'd change the world. But instead of trying to get people to support them, they occupy a public place and pretend to be smarter than the rest of the population.
will be for a good decade or so, one of these illnesses that people will blame or all sorts of mysterious "evils" that we experience in every day life.
Lead in petrol, mercury in the sea, vaccines, internet, WiFi, video games, contraceptive pills, pesticides, radon, highway noise, electrical cables, plastic soft drink bottles.... There'll always be some crazy self-promoting dickhead trying to get some publicity for himself with his stupid theory.
It's a natural human response to want to find the cause of something. That's why gods were invented (it doesn't have to be a rational cause). It's also why these theories occur around illnesses that are down to pure chance or at least not currently explained. You don't see many people blaming their chlamydia infection on aluminium pots, because it's well established what causes that disease! So things like lupus, other autoimmune conditions, cancer (not lung cancer), autism, tend to attract these kinds of lies.
But just because it's human nature give Baroness Susan Greenfield a reason to abuse her position with crap like this. Shame on her. She should know better. I hope she loses her job for making up bullshit (and purposely difficult to disprove bullshit) like this. She's meant to be a scientist, not a self-promoting celebrity.
Unity is not usable. It is not easy to use or intuitive.
Right-clicking should allow us to alter things. Things should be consistent. We don't need have the screen taken up with giant buttons - that doesn't help and it's not easy to use! It's just annoying.
Dammit no. I remember being a child and hearing that sound and cringing then finding out AFTER that I wasn't alone.
I have the same memory. I remember kids doing that on the chalkboard and wondering how come they could make that noise when it was such an awful sound for me.
(I also agree that communism sucks. It's only trendy talk amongst young hipsters, but it doesn't and can't work, and it's incredibly unfair.)
Is to outlaw unjust discrimination on basis of education. In other words, a job offer can't have education requirements that can't be justified (asking for just "college education" without specifying a degree is right out) , any more than one can hire personnel on the basis of what car they drive.
This is one of the smartest comments I have read here. I'm normally an opponent of government intervention, but the discrimination angle is actually quite a good idea. Obviously, if a degree is required for a job (i.e. doctor, architect, most scientists) then it's allowed, but you're right, it's prejudicial to require someone who is going to work in a clothes shop to have a university degree.
Having said that, I think it's a silly idea for employers to hire those with degrees for menial jobs - they're much more likely to leave and try to find somewhere better, while the person without a degree might consider making a career for him/herself by sticking around long enough.
Slashdot Mirror
He needs to release it as open source, and secretly patent the algorithm (or even patient the basic concept as Amazon and Apple have done). Wait until a better functioning company with a smarter owner starts using your code. Allow it to get really widespread and allow your competitor to get really successful with great marketing and hard work. Let them broker the deals, let them do the hard sell, let them spend their capital promoting it.
Then sue the bastards for patent violation.
The standard trolling xkcd is this:
goatse.cx
If this some popped into anyone else's head: 26^140 = 1 248 155 560 712 888 693 721 116 035 178 646 463 649 590 092 724 076 699 557 919 198 775 318 840 655 335 967 337 203 969 601 545 498 350 937 608 330 255 529 112 180 176 094 892 997 792 623 787 890 917 357 870 916 489 701 094 150 005 153 729 071 148 146 282 725 376
Obviously most of those are not sentences. And it ignores spaces and punctuation.
http://knowyourmeme.com/memes/fcking-magnets-how-do-they-work
The incorrect part is saying "An".
You should use "an" as the article if the next word begins with a vowel sound. So we say "a European" (pronounced you-row-pean), "a universal serial bus", "a U-boat", "a yellow banana". We say "an apple", "an honourable discharge", and "an yttrium semiconductor" (pronounced ittrium),
So the rule is based on the sound and how things flow, not the actual letter of the alphabet used.
I'm not normally squeamish, but that made me sick. I didn't actually wait until he put it in his mouth - I had to close the tab.
It could be the next goatse.
Stop it... Stop it...
You're a non-elected "government" full of overpaid ex- and failed politicians, and you're still trying to scam more money while Europe burns. Stop with the heavy intervention, you make me sick! Hopefully this EU thing is not going to last - Europe doesn't need dictators.
But the citizen's of Europe need some unelected representatives to be their nanny. They can't survive on their own!
I don't think it does. Most people go through customs, get the crap done, and then carry on with their holiday.
I hate to say this. I really do. But it needs to be said:
"Woosh"
Actually, the reason that some parts of chicken are white (e.g breast) while others are more brown (e.g. legs) is because of the type of muscle.
Slow twitch has more mitochondria, so is browner. Fast twitch is whiter meat.
So it's your personal preference as to the children you will eat.
Shameless (and copyvio) copy/paste from 23andMe:
This gene produces a protein called alpha-actinin-3 that is only turned on in fast-twitch muscle fibers (the kind used for power events like sprinting or weightlifting). The protein forms part of the contractile machinery in muscle cells, where it is thought to play both structural and signalling roles.
The T version of the SNP in this gene prevents the full protein from being made. People with two copies of the T version thus have a total lack of alpha-actinin-3 in their fast-twitch muscle fibers. Those with the CT genotype have one functional copy of the gene and can still make the protein.
Surprisingly, a complete lack of the alpha-actinin-3 protein doesn't seem to cause any type of disease. This is probably because another closely related protein can step in for alpha-actinin-3 in people without a functional copy. The substitute protein likely does not perform its job as well as alpha-actinin-3, resulting in worse performance in power exercises.
Despite lack of a disease outcome, researchers wondered if the absence of alpha-actinin-3 might have an effect on athletic performance. Studies of elite athletes in Australia and Finland showed that power athletes—those whose performance depends on fast-twitch muscle fibers—were much more likely to have at least one working copy of the gene than non-athletes. In one study of Olympic power athletes (i.e., the best of the best), all had at least one working copy. Similar results were found in a study of Spanish professional soccer players.
But does alpha-actinin-3 make a difference for non-athletes? In fact, it does.
One study looked at a group of Greek teenagers who had been tested for a variety of fitness measures related to power and endurance sports. In this group, ACTN3 genotype had no effect on the girls, but boys with the TT genotype were significantly slower in a 40 m sprint. Interestingly, running was the only power event that the different versions of ACTN3 seemed to affect. For activities like throwing a basketball or jumping into the air, performance was unaffected by genotype.
Another study looked at arm strength in a group of people before and after 12 weeks of strength training. ACTN3 genotype appeared to have no effect in men, but women with the TT genotype had lower strength at the beginning of the study. After the training program women with the TT genotype—those without a working copy of alpha-actinin-3—had made greater gains than the women with at least one functioning copy. This was true in both European and Asian women.
Scientists aren't really sure why having alpha-actinin-3 would improve power performance. One theory is that the protein prevents damage in fast-twitch muscle fibers. The group who conducted the study of Greek teenagers thinks this explains why only running and not other power activities were affected by a lack of alpha-actinin-3. Running involves repeated use of the muscles, while jumping only uses muscles once: damage is not an issue.
The scientists who saw that women with the TT genotype were able to build up more strength than other women also think alpha-actinin-3 protects muscle fibers from damage. Muscle damage is what stimulates muscles to adapt and become stronger. Those with the TT genotype lack the protection against damage that alpha-actinin-3 normally provides, thus allowing a greater gain in strength.
Alpha-actinin-3 may also affect athletic performance by virtue of its effects on oxygen usage in muscle. Two studies (one in mice and one in humans) have shown that fast-twtich muscle fibers that lack functional copies of ACTN3 use more oxygen than those with at least one working copy. This type of metabolism might slow them down. Mice studies have also shown that these altered fibers are weaker and smaller than fibers containing alpha-actinin-3, but they are more efficient an resistant to fatigue—a situation that is better suited to endurance sports than sprinting.
Well, not really a scam, but it's incredibly overpriced and gives you no useful information. That gene has very little effect outside of maybe the elite of the elite. Your body shape contributes much much more to your "ideal" sport. (More important is what the kid enjoys.)
For $200, you can test 500,000 SNPs with 23andMe, get much more useful health info plus ancestry information.
My result from 23andMe:
rs1815739:CT "One working copy of alpha-actinin-3 in fast-twitch muscle fiber. Many world-class sprinters and some endurance athletes have this genotype."
I've actually seen a number of companies that test for a few SNPs, charging $hundreds and making misleading claims. I can't say for sure if they're fly-by-nighters out to make a buck, but there are much cheaper ways of getting more information.
I'm not American, but those occupy protests aren't middle anything. They're just protesters and hipsters, each with their own agendas, who sit and masturbate about how they'd change the world. But instead of trying to get people to support them, they occupy a public place and pretend to be smarter than the rest of the population.
We've even got them in NZ.
Are you planning to buy your wife a new mophead, a scouring pad and some oven cleaner for Xmas?
What child wouldn't want a copy of 7-Zip for Christmas? You'd be the coolest uncle in the world!
For their birthday you could get them pngcrush! And maybe, for a treat, you could include an update for the Windows PCI device driver.
Oh bullpoop.
There now, there's no need for profanity, Fallout Boy.
Look at Cambodia. They did Communism right, and that was fucking terrible.
It's actually most likely that you did have the flu.
will be for a good decade or so, one of these illnesses that people will blame or all sorts of mysterious "evils" that we experience in every day life.
Lead in petrol, mercury in the sea, vaccines, internet, WiFi, video games, contraceptive pills, pesticides, radon, highway noise, electrical cables, plastic soft drink bottles.... There'll always be some crazy self-promoting dickhead trying to get some publicity for himself with his stupid theory.
It's a natural human response to want to find the cause of something. That's why gods were invented (it doesn't have to be a rational cause). It's also why these theories occur around illnesses that are down to pure chance or at least not currently explained. You don't see many people blaming their chlamydia infection on aluminium pots, because it's well established what causes that disease! So things like lupus, other autoimmune conditions, cancer (not lung cancer), autism, tend to attract these kinds of lies.
But just because it's human nature give Baroness Susan Greenfield a reason to abuse her position with crap like this. Shame on her. She should know better. I hope she loses her job for making up bullshit (and purposely difficult to disprove bullshit) like this. She's meant to be a scientist, not a self-promoting celebrity.
Well, nerds of European descent...
The genetic risk of alcoholism and extroversion from 23andMe:
http://spittoon.23andme.com/2011/10/21/genes-and-geography/
And more along the lines of the original story:
Parkinson's and BCC
That's the exact problem!
Unity is not usable. It is not easy to use or intuitive.
Right-clicking should allow us to alter things. Things should be consistent. We don't need have the screen taken up with giant buttons - that doesn't help and it's not easy to use! It's just annoying.
How do i get money to 'study' such amazingly useless and stupid things like this...
You think knowing about the human response to sound is useless?
Dammit no. I remember being a child and hearing that sound and cringing then finding out AFTER that I wasn't alone.
I have the same memory. I remember kids doing that on the chalkboard and wondering how come they could make that noise when it was such an awful sound for me.
(I also agree that communism sucks. It's only trendy talk amongst young hipsters, but it doesn't and can't work, and it's incredibly unfair.)
Is to outlaw unjust discrimination on basis of education. In other words, a job offer can't have education requirements that can't be justified (asking for just "college education" without specifying a degree is right out) , any more than one can hire personnel on the basis of what car they drive.
This is one of the smartest comments I have read here. I'm normally an opponent of government intervention, but the discrimination angle is actually quite a good idea. Obviously, if a degree is required for a job (i.e. doctor, architect, most scientists) then it's allowed, but you're right, it's prejudicial to require someone who is going to work in a clothes shop to have a university degree.
Having said that, I think it's a silly idea for employers to hire those with degrees for menial jobs - they're much more likely to leave and try to find somewhere better, while the person without a degree might consider making a career for him/herself by sticking around long enough.