Slashdot Mirror


Darwinian Evolution Considered As a Phase

LucidBeast tips a mind-bending report at New Scientist on the latest paradigm-breaking work of Carl Woese, one of whose earlier discoveries was the third branch of life on Earth, the Archaea. Woese and physicist Nigel Goldenfeld argue that, even in its sophisticated modern form, Darwin's theory of evolution by natural selection applies only to a recent phase of life on Earth. Woese and Goldenfeld believe that horizontal evolution led to the rise of the genetic code itself. "At the root of this idea is overwhelming recent evidence for horizontal gene transfer — in which organisms acquire genetic material 'horizontally' from other organisms around them, rather than vertically from their parents or ancestors. The donor organisms may not even be the same species. This mechanism is already known to play a huge role in the evolution of microbial genomes, but its consequences have hardly been explored. According to Woese and Goldenfeld, they are profound, and horizontal gene transfer alters the evolutionary process itself."

313 comments

  1. I realize scientists need a breakthrough by Blappo · · Score: 3, Insightful

    I strongly suspect it isn't, nor was it ever, one type of evolution over the other, but a complex interaction between many environmental pressures where both types of evolution played a role.

    --
    Why are so many posts with factual errors modded up?
    1. Re:I realize scientists need a breakthrough by biryokumaru · · Score: 3, Interesting

      Similar to the silly "nature versus nurture" debate, I think the key here is that for different critters, different types of evolution are significantly more dominant.

      --
      When you're afraid to download music illegally in your own home, then the terrorists have won!
    2. Re:I realize scientists need a breakthrough by Anachragnome · · Score: 2, Insightful

      I agree.

      It always seemed a little odd that evolutionists minimized such interactions as the bacteria that lives on, and IN, us as little more then a symbiotic relationship.

      The idea that some genetic material might actually be passed from ourselves to these bacteria, or the other way around, seemed to make sense. I'm not talking about large chunks of DNA, but rather a codon or two every dozen generations, or something to that effect. Given that mutations/variations are more likely to occur in two species, as opposed to one, that symbiotic relationship might have accelerated genetic changes in either, or both, species. Who knows, maybe our ability to digest some specific foodstuff (a foodstuff that we previously relied on a bacteria in our gut to help us digest/process) was derived from genetic material that originally came from a bacteria that had the ability but was passed on to us a codon at a time. Just an example.

      This leads me to the question of whether or not our preoccupation with sanitization/sterilization of our own bodies might be having some detrimental effect on our EVOLUTION. Is our wiping out species, to the point of extinction, actually limiting the evolutionary process, in essence limiting variation in the exchange of genetic material?

    3. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 0

      All I know is the story I heard when I was still a little kid, that chlorophyll wasn't originally a part of plants.

      It was somewhat like the "horizontal transfer" thingy, and got merged into the plant's genetic code.

    4. Re:I realize scientists need a breakthrough by Thiez · · Score: 2, Interesting

      > The idea that some genetic material might actually be passed from ourselves to these bacteria, or the other way around, seemed to make sense. I'm not talking about large chunks of DNA, but rather a codon or two every dozen generations, or something to that effect. Given that mutations/variations are more likely to occur in two species, as opposed to one, that symbiotic relationship might have accelerated genetic changes in either, or both, species. Who knows, maybe our ability to digest some specific foodstuff (a foodstuff that we previously relied on a bacteria in our gut to help us digest/process) was derived from genetic material that originally came from a bacteria that had the ability but was passed on to us a codon at a time. Just an example.

      You're crazy. Let's assume for the sake of argument that DNA from a bacterium will sometimes end up in a nearby human cell. Since the bacteria in your example live in your guts, they will share DNA with cells in your guts. These cells are not involved in procreation and therefore their 'mutations' will not be inherited and therefore they do not influence human evolution.

      The only way to make this work (still assuming the DNA trading between human cells and bacteria is possible) would be if sperm or an egg somehow were to come in contact with bacteria from your guts. I don't think the whole 'ass-to-pussy' thing that I may or may not have accidentally stumbled upon at some point in my life while searching for, eeeeh, educative programming related articles is so widely practiced that it has a significant effect on human evolution ( except when you get a horrible infection and die :p ).

    5. Re:I realize scientists need a breakthrough by Opportunist · · Score: 1

      Well, ass-to-pussy maybe not, but ass to something else has been tried time and again. And research, studies and actual experiments are going on, probably as we speak.

      It's just news to me that it has anything to do with the procreation process.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    6. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 1, Interesting

      The idea that some genetic material might actually be passed from ourselves to these bacteria, or the other way around, seemed to make sense. I'm not talking about large chunks of DNA, but rather a codon or two every dozen generations, or something to that effect. Given that mutations/variations are more likely to occur in two species, as opposed to one, that symbiotic relationship might have accelerated genetic changes in either, or both, species. Who knows, maybe our ability to digest some specific foodstuff (a foodstuff that we previously relied on a bacteria in our gut to help us digest/process) was derived from genetic material that originally came from a bacteria that had the ability but was passed on to us a codon at a time. Just an example.

      Actually, this does not make sense and I can't believe this was modded insightful. Other than the fact that the structure of genes in eukaryotes (with a complex intron/exon structure) versus prokaryotes (that usually have genes structured in operons) would prevent horizontal gene transfer from occurring, passing DNA codon by codon would never work in a probabilistic sense. The hope that moving small (i.e. 3 nucleotides) piece of DNA from one organism to another would land in a gene (which is less than 2% of the human genome) and then even land in a portion of that gene to cause a functional change (much less a positive functional change) is so infinitesimal it is absurd. Moreover, for these changes to be inherited, they would need to occur in the germ lines of a human, not in somatic cells. The location of germ line cells is kept bacteria-free under normal conditions, so no possibility of horizontal transfer.

      Plus, any time you study an eukaryotic organism that has a unique ability to digest a non-typical food source (e.g. termites), it is the result of a symbiotic relationship with gut bacteria that produce enzymes (via their own genes) to digest the materials, not by DNA transfer.

      This leads me to the question of whether or not our preoccupation with sanitization/sterilization of our own bodies might be having some detrimental effect on our EVOLUTION. Is our wiping out species, to the point of extinction, actually limiting the evolutionary process, in essence limiting variation in the exchange of genetic material?

      No. At worst it creates open niches for infectious bacteria to inhabit, but no DNA transferring is lost.

    7. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 0

      'Both' ? I hope you mean 'many'. 'Natural Selection' is one mechanism of evolution, 'Sexual Selection' is another. 'Horizontal Gene Transfer' is just another. They all work together or separately in driving evolution.

    8. Re:I realize scientists need a breakthrough by tempest69 · · Score: 1
      as far as humans getting genes from viruses and bacteria.. it is small change relative to recombination, mutation and gene duplication. Germline cells are really resistant to alterations in general. Bacteria and viruses could make some changes here and there, but they need to hit a cell that will create offspring, and not leave it (said offspring) jacked up.

      The much more common event is gene duplication and neofunctionilization, A normally occuring protien gets duplicated, and is no longer under pressure to work, eventually they get "fired" or go feral, doing something new that provides an advantage to a creature. Eventually causing their new job to be selected for.

      So bacteria giving us proteins is rare in the here and now. Though hyper sanitary conditions do leave people with some real problems, as we didnt evolve into cleanness.

    9. Re:I realize scientists need a breakthrough by Ihmhi · · Score: 1

      What's the kinda of evolution where you wave around a crystal to turn one Pokémon into another? I'm more in favor of that one. Crystalian evolution.

    10. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 1, Interesting

      Not that crazy. There is a lot of so-called junk DNA in our genome (as in: DNA without any known function), and I have heard before that many genetic researchers believe this junk DNA comes from viruses originally. I don't recall about bacteria leaving their mark in our genome, and considering viruses aren't much more than a chunk of DNA or RNA that likes to enter a host's cells it makes more sense to pick up some DNA from viruses than from bacteria.

      How that virus DNA ended up in our genome I don't know, that was not mentioned, there are presumably theories about it but I haven't ever read about that. I would expect indeed that the only plausible way would be during conception of a baby. Or during production of egg/sperm cells.

    11. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 0

      I highly recommend checking out The Selfish Gene. It's a great book. And between the stuff they leave out in school biology and the mists of time, it's very easy to get confused about the mechanics of how genes propagate.

      Specifically, as another poster already commented: genes don't get passed on sexually reproducing organisms unless they make their way into the act of reproduction.

      Some of our genetic code has been demonstrated to be viral (in particular, the mammalian placenta contains a comparatively large amount of viral code). But what you're talking about (bacteria lending their abilities to our digestive organs and that somehow getting passed on) simply doesn't happen. What *does* happen that's perhaps more interesting is coevolution...we could have evolved in such a way that made our stomachs more hospitable for the bacteria, for instance. There are some really colorful examples of coevolution happening with orchids, check out WP for more. Also, Dawkins' latest book has some nice glossy pictures concerning this.

    12. Re:I realize scientists need a breakthrough by ultranova · · Score: 1

      Ironically enough, evolving through acquired traits is once again becoming the dominant type in the form of cultural transfer, making us closer to our bacterial roots than the intervening steps.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    13. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 0

      It's more exciting to the common knucklehead if it looks like there is going to be a winner or loser.

      Also, there's no such thing as evolution. 4000 years is not nearly long enough for us to have evolved from lizard men.

    14. Re:I realize scientists need a breakthrough by ajlisows · · Score: 1

      It has been awhile, but I was once a Biochemist working in a gene therapy lab. We encased DNA in a polymer that had proteins that would cause the package to be delivered to the desired organ attached to the polymer with PEG. Once the package bonded to its target, the polymer had to be weak enough that it would break apart and release the DNA (of course, it had to be strong enough to get there....a very delicate balance that made this tricky.) We would pass it off where it was administered to lab rats and expression would be measured.

      I may not be precise in my numbers here, but they are close enough to illustrate the point. Our target uptake percentage that would ensure expression was 5%, meaning if we could deliver to the target organ and have the DNA incorporate it into the lab animal's DNA in the target organ it would be sufficient for gene therapy to be successful. I did not highly research that number myself, but it was generally accepted to be the magic number. Anyway, to give a baseline, they periodically did control tests, where the lab rat would be administered just free floating DNA. This is where I reach my point. The expression in these control subjects was nearly 1%! Although this was under unrealistic circumstances (large quantities of a single gene injected into the target) it does go to show that the uptake of free floating DNA is probably quite common.

    15. Re:I realize scientists need a breakthrough by fusellovirus · · Score: 2, Informative

      This is old news, Woses paper "on the evolution of cells" explained this concept 8 years ago http://www.pnas.org/content/99/13/8742.long. Even within the protocell or primordial soup where horizontal gene transfer is hypothesized to play a dominant role natural selection still takes place. The molecules that replicate best increase in number and those that don't die out. Also, several evolutionary biologists such as Woese himself and many of his collegues have made their careers out of studying this phenomenon, so the suggestion " its consequences have hardly been explored" is a bit disingenuous.

    16. Re:I realize scientists need a breakthrough by Anonymous Coward · · Score: 0

      Is our wiping out species, to the point of extinction, actually limiting the evolutionary process, in essence limiting variation in the exchange of genetic material?

      Have no fear! There is always the herpes simplex to lean on.

    17. Re:I realize scientists need a breakthrough by Thiez · · Score: 1

      I know about retroviruses and how they are able to end up in your DNA (wikipedia suggests 5-8% of our DNA comes from such viruses), but that was not what GGP was suggesting. He was suggesting human cells can exchange DNA with other cells, which is not true. Cells trading DNA does happen, but that is limited to bacteria (wikipedia 'plasmid'). Humans cannot 'learn' to digest certain foods from the bacteria in their guts.

    18. Re:I realize scientists need a breakthrough by mhelander · · Score: 1

      I wonder why this would not be called Darwinian evolution by natural selection? The modern synthesis considers self replicating entities, they don't have to replicate "vertically" - "horizontally" works just as well. This seems like yet a misinformed attack on Darwinism, such that someone investigates a particular feature of Darwinian evolution, and because it doesn't look exactly like what they were taught Darwinism to be, they think it is something else. But it isn't.

    19. Re:I realize scientists need a breakthrough by hesaigo999ca · · Score: 1

      Yes, as well, one bacteria originating from one source affects another...so let's say a dog has a virus that spreads to humans, and makes the humans susceptible or immune to that virus, but leaves a trace that mutates in the genes further generations down the line...this is what I am thinking they mean, cross species barriers being bypassed....and ending up mutating due to evolution.

    20. Re:I realize scientists need a breakthrough by mcgrew · · Score: 1

      According to a recent story on slashdot, horizontal evolution is still working even on humans. I haven't had enough coffee for my brain to work good enough to remember the details, but viruses infecting a host's reproductive organs can pass the virus' genetic code to the host's offspring, changing the offsprings genetic code. IIRC TFA said that they thought this causes some kinds of mental illnesses, but beneficial codes could be passed along as well. Just as there is no nature vs nurture, that it's actually both, it seems that there is both horizontal and vertical evolution, even in modern species (although of course vertical evolution is now dominant, while TFS says in early life there was no vertical evolution).

    21. Re:I realize scientists need a breakthrough by john8-32 · · Score: 0

      I do not suspect...but I KNOW that neither of these is true. God Himself is the Creator of all that man can see and can not see. The natural and the supernatural. It never ceases to amaze a regular person like me...that you self-important "Scientists"-(FYI Jehovah GOD is the Chief Scientist of all)-grasp desperately at any alternative, OTHER than GOD, that comes down the humanists pike through which the majority of scientific self-inflated "egos" feed off one another.Ever preening before each other. Like Richard Dawkins who clings so desperately to his delusions..no matter what the evidence for Design and THE super-intelligent, all Powerful Designer is. Stephen Hawkings is the brilliant one in relation to created man--he KNOWS and has stated this fact...that Evidence for a Grand Designer is everywhere. Truly I feel sorry for all who figure they can do away with God....it's so sad to see. Believe me when I do not say this in any way mockingly..but because I care. You understand that YOU cannot save anyone-not even yourselves- from what is to come upon this earth..and in God's Perfect Timing, upon all those who reject God's Son, mankind's Savior on the Day of Judgment -before Whose Throne of Holiness and Righteousness the unrepentant will stand. 1 Corinthians 18:25~"For to those who are perishing the message of the cross is foolishness, but to us who are being saved it is God's power. For it is written: I will destroy the wisdom of the wise, and I will set aside the understanding of the experts. Where is the philosopher? Where is the scholar? Where is the debater of this age? Hasn't God made the world's wisdom foolish? For since, in God's wisdom, the world did not know God through wisdom, God was pleased to save those who believe through the foolishness of the message preached. For the Jews ask for signs and the Greeks seek wisdom, but we preach Christ crucified, a stumbling block to the Jews and foolishness to the Gentiles. Yet to those who are called, both Jews and Greeks, Christ is God's power and God's wisdom, because God's foolishness is wiser than human wisdom, and God's weakness is stronger than human strength. Romans 1:18-25~" For God's wrath is revealed from heaven against all godlessness and unrighteousness of people who by their unrighteousness suppress the truth, since what can be known about God is evident among them, because God has shown it to them. From the creation of the world His invisible attributes, that is, His eternal power and divine nature, have been clearly seen, being understood through what He has made. As a result, people are without excuse. For though they knew God, they did not glorify Him as God or show gratitude. Instead, their thinking became nonsense, and their senseless minds were darkened. Claiming to be wise, they became fools and exchanged the glory of the immortal God for images resembling mortal man, birds, four-footed animals, and reptiles. Therefore God delivered them over in the cravings of their hearts to sexual impurity, so that their bodies were degraded among themselves. They exchanged the truth of God for a lie, and worshiped and served something created instead of the Creator, who is blessed forever. Amen. Truly He is God Almighty..and there is none other God besides He. I share this with you in the love of Jesus Christ.

    22. Re:I realize scientists need a breakthrough by Mr.+Firewall · · Score: 1

      ...and horizontal gene transfer alters the evolutionary process itself...

      ...horizontal evolution is still working even on humans.

      Yeah, all of my kids got their DNA from a "horizontal gene transfer"...

      --
      In times of universal deceit, telling the truth gets you modded -1 Troll
    23. Re:I realize scientists need a breakthrough by mcgrew · · Score: 1

      Why won't Baptists have sex standing up?

      They're afraid someone will see them and think they're dancing!

  2. Proven example: by Monkeedude1212 · · Score: 5, Funny

    The first 2 parts of Spore are like Horizontal Evolution, and the later parts are all vertical.

    It makes perfect sense. Clearly Will Wright is a genius.

    1. Re:Proven example: by Opportunist · · Score: 1

      Maybe he is, but all I asked from him was to create a game worth playing. What good is a genius if it keeps him from doing his job well?

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    2. Re:Proven example: by Anonymous Coward · · Score: 0

      ah, so you are suggesting that such a system requires "genius"? you're fired.

  3. Neo-Lamarkian Evolution by Anonymous Coward · · Score: 0

    This would be epigenetic, neo-Lamarkian evolution, with the inheritance of acquired traits.

    Not: Larkian evolution is NOT Lysenkoian evolution.

  4. Well duh? by tzenes · · Score: 3, Informative

    For anyone familiar with the Red Queen Hypothesis ( http://en.wikipedia.org/wiki/Red_Queen ) this should be obvious.

    While direct DNA transfer is not the component usually referred to by this "arms race," it is merely an extension of a known theory.

    No one makes a big hype about this theory, because it doesn't say your grandfather was a monkey and piss off the religious nuts

    1. Re:Well duh? by Toonol · · Score: 1

      I can't read the article without registering but I wonder if homosexual behavior could be causing horizontal gene transfer in humans.

      Sometimes vertical transfers, too.

    2. Re:Well duh? by Bovius · · Score: 2, Insightful

      As opposed to heterosexual behavior? I hear the fluids transferred are remarkably similar.

    3. Re:Well duh? by UnknowingFool · · Score: 1

      Also to note, this doesn't supplant Darwinian evolution but adds to it. I can see that this might be plausible in the early stages of life on this planet where microbes would acquire genes from other microbes. I'm wondering if the proponents consider the mitochondria as one example of this horizontal evolution?

      --
      Well, there's spam egg sausage and spam, that's not got much spam in it.
    4. Re:Well duh? by jhoegl · · Score: 1

      Yeah, but one is less gay than the other.

    5. Re:Well duh? by Arancaytar · · Score: 2, Informative

      To be precise, there is no theory that says your grandfather was a monkey. The religious nuts made that straw-man up all on their own. :P

    6. Re:Well duh? by Guido+von+Guido · · Score: 4, Informative

      I can't read the article without registering but I wonder if homosexual behavior could be causing horizontal gene transfer in humans, possibly using viruses as a transport mechanism.

      If viruses are your transport mechanism, I'm not sure you need homosexual behaviour. You may, yes, but there are plenty of other mechanisms for viruses to spread.

    7. Re:Well duh? by Arthur+Grumbine · · Score: 1

      To be precise, there is no theory that says your grandfather was a monkey. The religious nuts made that straw-man up all on their own. :P

      I beg to differ. Although still struggling for broad acceptance, the theory that you are the retarded offspring of 5 monkeys and a fish-squirrel is being taught in our schools.

      --
      Now that I think about it, I'm pretty sure everything I just said is completely wrong.
    8. Re:Well duh? by MichaelSmith · · Score: 1

      Agreed so lets narrow the question: could humans who engage in activities which encourage the exchange of viruses be exchanging genes at the same time?

    9. Re:Well duh? by wealthychef · · Score: 3, Insightful

      Just why is it that ultra-conservative rants about God or racial superiority or anti-socialism are instantly modded off-topic, troll, and/or flamebait until they sink beneath the thresh hold

      You're seriously asking this question?

      and yet completely off-topic attacks on Creationism in every story even vaguely connected with biology or evolution get modded +5 insightful?

      I think you are exaggerating.

      --
      Currently hooked on AMP
    10. Re:Well duh? by RobinEggs · · Score: 1, Insightful

      I think you are exaggerating.

      I'm not exaggerating in the least; look around. I see at least one +5 post in every biology or evolution topic that exclusively concerns bashing creationism and only half of the time even mentions the topic at hand.

      You're seriously asking this question?

      Of course I'm not seriously asking why ultra-conservative rants get modded down as if I believe they shouldn't, I was just contrasting the constant stream of hate stupid, vitriolic conservatives get with the near-acceptance stupid, vitriolic anti-Christians receive.

    11. Re:Well duh? by CrimsonAvenger · · Score: 4, Interesting

      I can see that this might be plausible in the early stages of life on this planet where microbes would acquire genes from other microbes.

      I saw an article recently about a species of snail that has acquired the genes for making chlorophyll from the algae it eats. It hasn't yet acquired the genes to make chloroplasts, so it has to eat algae to get enough chloroplasts from the algae to allow photosynthesis to work, but after that it is capable of living with no food other than light.

      So, obviously this is still ongoing, and on larger scales than microbes.

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
    12. Re:Well duh? by bzdyelnik · · Score: 0

      Yes - change "homosexual sex" to "non-procreative sex" and it's less controversial. What about just the human behavior of kissing? Perhaps it's a way of smelling each other's breath to check for disease signals, or sharing of pheromones, but I'm more inclined to think it's about virus transfer. I'd also presume that breast feeding might provide lateral transfer of beneficial genes via viruses that haven't "gone germline" yet. Viruses can also pass through the placenta to a fetus, and viruses can pass the blood-brain-barrier. It's possible that a beneficial virus could get passed around that actually changes human thought/behavior. A rabies infection makes a person hydrophobic, but rabies isn't exactly beneficial (except maybe to bats). Even more wacky - what if human rational consciousness is a function of one or many viruses that get transferred to embryos/fetuses/developing children? Perhaps over time some of those viruses have "gone germline" and are now HERVs. In that case God would not only be a viral meme, but also a molecular virus (or series of 'em) himself.

    13. Re:Well duh? by oldhack · · Score: 1

      Yes, but Apple has patents on that, and you now have put your life at the risk of predatory Apple lawyers for bringing this up.

      You're so screwed.

      --
      Fuck systemd. Fuck Redhat. Fuck Soylent, too. Wait, scratch the last one.
    14. Re:Well duh? by cortesoft · · Score: 1

      On Slashdot, we discuss science, technology, and computers (logic machines). Creationism is anti-science and anti-logic. Wouldn't it make sense that posts arguing against science and logic would be modded down on such a site?

    15. Re:Well duh? by RobinEggs · · Score: 1

      Nice job not even reading any of my posts or any of the respondents. I was discussing non-Creationists who warp biological topics into an excuse to attack Creationism, despite the fact that the Creationists usually aren't here and aren't posting.

      So no, I wasn't disagreeing with modding down anti-scientic and anti-logical topics, I was disagreeing with going out of one's way to bring up anti-scientific topics just to ridicule them.

    16. Re:Well duh? by DMiax · · Score: 1

      Mutations in multicell organisms are relevant only when they affect the reproductive system. A single DNA change in a human's skin cell is only likely to give cancer. Horizontal transfer in humans can be ruled out until further discoveries, I suppose. Like, if some virus is non nocive and specifically targets embryos...

    17. Re:Well duh? by Alphathon · · Score: 1

      FYI it still needs to eat, just not for energy. Still needs other things, like the components to build proteins.

    18. Re:Well duh? by MichaelSmith · · Score: 1

      But what if the acquired gene has a later opportunity to jump ship? It may not need a working reproductive system.

    19. Re:Well duh? by claar · · Score: 1

      the religious nuts

      Completely unnecessary. While I may personally be a bit nutty, I never cease to be amazed at how the "tolerant left" is anything but.

      --
      I'd give my right arm to be ambidextrous...
    20. Re:Well duh? by EllisDees · · Score: 1

      If they don't reproduce, it's going to be a little difficult.

      --
      -- Give me ambiguity or give me something else!
    21. Re:Well duh? by Tomfrh · · Score: 1

      To be precise, there is no theory that says your grandfather was a monkey.

      Exactly. We haven't been monkeys for at least 100 generations. Heck, maybe even 200...

    22. Re:Well duh? by Anonymous Coward · · Score: 0

      The sad fact is that children born HIV-positive do not live very long. So no, it's not.

      Also: fuck you.

    23. Re:Well duh? by T+Murphy · · Score: 1

      Sorry to link Fox News, but it was the first news report on this slug I could find: link

    24. Re:Well duh? by The+End+Of+Days · · Score: 4, Interesting

      Creationism is ridiculed because creationism is ridiculous. Such posts get modded up because people with mod points agree, whether on topic or not. It's not really worth a sociology paper or anything.

      If you really want to defend creationism on /., I salute your bravery. If you are just trying to figure out why people do what they do, I wish you tremendous amounts of luck.

    25. Re:Well duh? by timmarhy · · Score: 3, Insightful

      anyone that thinks the world is 6000 year old and that a big man in the sky planted fossils to test our faith is nuts. it's about as fesible as the flat earth believers, and since they REFUSE to listen to any of the 10000000's of peices of evidence one can only conclude they are in fact crazy.

      --
      If you mod me down, I will become more powerful than you can imagine....
    26. Re:Well duh? by Anonymous Coward · · Score: 0

      That isn't gene transfer. Too tired to write an actual rebuttal, but... mitochondria, termite guts, etc

    27. Re:Well duh? by Thiez · · Score: 1

      > What about just the human behavior of kissing? Perhaps it's a way of smelling each other's breath to check for disease signals, or sharing of pheromones, but I'm more inclined to think it's about virus transfer. I'd also presume that breast feeding might provide lateral transfer of beneficial genes via viruses that haven't "gone germline" yet

      As a rule, your body 'dislikes' viruses, and will not attempt to acquire them. As far as I know there are no viruses that have a positive effect on their hosts, and even if there were, your body would have no way to sort them from the bad viruses. I think your theory is extremely unlikely to be true, especially since AFAIK so far no evidence has been found that suggests it may be happening. Also even if there was an advantage to acquiring some viruses, it's probably easier to wait a generation for it to "go germline" than to evolve a very complex mechanism that allows for viruses to be shared between individuals (as if viruses need help with that...).

    28. Re:Well duh? by Thiez · · Score: 1

      Elaborate.

    29. Re:Well duh? by MichaelSmith · · Score: 1

      Exactly how it got into the organism, by horizontal gene transfer. If we assume it got in by using a retrovirus as a vector, it can get out the same way. The idea process would be to jump from an older host in poor condition to a younger host in better condition.

    30. Re:Well duh? by chthon · · Score: 1

      Or these people that went studying physics at the university, but refuse to believe that rockets can leave the earth.

    31. Re:Well duh? by Thiez · · Score: 1

      HIV fits your description. There are not, as far as I am aware, any viruses that bestow positive genes on those who are infected with them (with the exception of those engineered for gene therapy, your leukemi^Wmileage may vary).

    32. Re:Well duh? by Tim+C · · Score: 1

      Such posts get modded up because people with mod points agree, whether on topic or not.

      Which is of course an abuse of moderation; note there is no "+1, I Agree" option.

    33. Re:Well duh? by renoX · · Score: 3, Informative

      I wonder why this is moderated insightful?
      This is a very different kind of 'acquisition' as the genes for making chlorophyll acquired from the algae are not transferred to its offspring..

    34. Re:Well duh? by claar · · Score: 1

      anyone that thinks the world is 6000 year old and that a big man in the sky planted fossils to test our faith is nuts. it's about as fesible as the flat earth believers, and since they REFUSE to listen to any of the 10000000's of peices of evidence one can only conclude they are in fact crazy

      While I understand that many do not believe that God exists, that hardly excuses treating those who do without respect.

      There are "10000000's of peices [sic] of evidence" that God exists, and I'm guessing you "REFUSE to listen to any of" them -- so may I conclude that you are in fact crazy?

      --
      I'd give my right arm to be ambidextrous...
    35. Re:Well duh? by Danse · · Score: 2, Informative

      This is a very different kind of 'acquisition' as the genes for making chlorophyll acquired from the algae are not transferred to its offspring..

      According to this article, the genes are transferred, but the offspring, like the parents, can't produce their own chloroplasts, so have to eat enough algae to acquire the necessary chloroplasts before they can survive like that.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    36. Re:Well duh? by BJ_Covert_Action · · Score: 1

      If you are just trying to figure out why people do what they do,

      When it comes to slashdot mods, PCP is the only reasonable answer to this inquiry.

    37. Re:Well duh? by Danse · · Score: 1

      There are "10000000's of peices [sic] of evidence" that God exists

      [citation neeeded]

      While I understand that many do not believe that God exists, that hardly excuses treating those who do without respect.

      It's not the belief in God that engenders this disrespect, it's the attempts to get these beliefs taught in schools as science or made into law in order to impose religoius beliefs, or at least behavior, on others. I have quite a few relgious friends, but I don't consdier them to be religious nuts because they don't do these things and they understand that religion is a personal issue and not one that should be pushed or imposed on others.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    38. Re:Well duh? by Danse · · Score: 1

      Such posts get modded up because people with mod points agree, whether on topic or not.

      Which is of course an abuse of moderation; note there is no "+1, I Agree" option.

      There's a +1 funny and +1 underrated. These seem more than sufficient to mod up such posts. That and it's just good clean fun to laugh at people doing ridiculous things. About half the entertainment media in existence seems to confirm that.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    39. Re:Well duh? by RobinEggs · · Score: 1

      If you really want to defend creationism on /., I salute your bravery.

      Because of course even mentioning what assholes you guys are about Creationism must prove that I'm defending it. I've done nothing whatsoever to defend it, I've just questioned your behavior towards it in the distinct absence of it.

    40. Re:Well duh? by claar · · Score: 1

      First, thanks for the first non-inflammatory comment of the thread (yes, mine included). Now, to be slightly rude to you and take your quote completely out of context to prove a point that you weren't even arguing (sorry!! Also, I won't bother to address your [citation needed] request, even though not addressing points when replying to posts is a personal pet-peeve of mine. Whoops. Google is your friend, though)

      I have quite a few [pick a race] friends, but I don't consdier them to be [racial insult] because

      This is the problem I have -- it seems many argue that it's OK to call Christians "religious nuts" since they exhibit behavior that they do not approve of. While these same people, in most cases, preach "tolerance" in every other instance (other races, homosexuality, gender equality... pick your issue), and even call Christians intolerant because they live with integrity to their believe system (yes, the Bible says homosexuality is a sin. Yes, the Bible says the man is the head of the household.).

      But this is hypocritical in my opinion -- if I as a Christian *didn't* live according to the Bible, I expect many of these "same people" (now it's getting vague as to whom I'm referring to -- oh well) would condemn me similarly as they do *because* I believe what the Bible says. So why do these (who??) tolerance preachers have no tolerance themselves?

      (wow -- not my best-worded or best-argued comment ever.. oh well, gotta run to a meeting -- flame on.)

      --
      I'd give my right arm to be ambidextrous...
    41. Re:Well duh? by renoX · · Score: 1

      Thanks for the correction.

    42. Re:Well duh? by bzdyelnik · · Score: 1

      I'd say there's an extreme bias in our current understanding of viruses because we only know about the ones that are blooming (lytic phase) during acute disease symptoms. We know very little about viruses that don't cause disease, or the viruses hiding around in latent form (say, non-blooming herpes) because there's no easy way to find them (even when we know their genomic sequence and have antibodies to tag their coats).

    43. Re:Well duh? by Danse · · Score: 1
      I think I'll just agree to drop the citation issue since we'd end up arguing just that until somebody falls over dead most likely.

      This is the problem I have -- it seems many argue that it's OK to call Christians "religious nuts" since they exhibit behavior that they do not approve of. While these same people, in most cases, preach "tolerance" in every other instance (other races, homosexuality, gender equality... pick your issue), and even call Christians intolerant because they live with integrity to their believe system (yes, the Bible says homosexuality is a sin. [carm.org] Yes, the Bible says the man is the head of the household [carm.org].).

      Not just behavior that I don't approve of, it's behavior that seeks to impose their beliefs on me, and even to teach them to kids as science. Hell yeah, I oppose that. I'm well aware of what the bible says, and as far as I'm concerned, Christians need not participate in homosexual behavior if they believe it to be a sin, and they can run their households however they want. Just quit trying to impose that crap on the rest of us.

      But this is hypocritical in my opinion -- if I as a Christian *didn't* live according to the Bible, I expect many of these "same people" (now it's getting vague as to whom I'm referring to -- oh well) would condemn me similarly as they do *because* I believe what the Bible says. So why do these (who??) tolerance preachers have no tolerance themselves?

      Please live how you like. Just don't try to force the rest of us to live as you choose to.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    44. Re:Well duh? by claar · · Score: 1

      As long as you choose the words "impose" and "force", I will agree with you (on this, at least).

      While Christians are expressly commanded to evangelize and not be ashamed of the Gospel, "imposing" and "forcing" are not Biblical ideas from what I read. While on earth, Jesus preached to those who came out to hear Him or entered the synagogue He was teaching in, and He desires followers to believe in Him of their own will.

      That being said, as a Christian, I support laws that may very well impose on others (without sacrificing freedom of religion -- again, followers should *freely* choose to believe) such as anti-abortion, protection of marriage, and other biblically-rooted legislation. This source says it better than I can:

      Whether law is based upon moral absolutes, changing consensus, or totalitarian whim is of crucial importance. Until fairly recently, Western culture held to a notion that common law was founded upon God's revealed moral absolutes.

      In a Christian view of government, law is based upon God's revealed commandments. Law is not based upon human opinion or sociological convention. Law is rooted in God's unchangeable character and derived from biblical principles of morality.

      In humanism, humanity is the source of law. Law is merely the expression of human will or mind. Since ethics and morality are man-made, so also is law. Humanists' law is rooted in human opinion, and thus is relative and arbitrary.

      If that's imposing and forcing, and I suppose it is, label me guilty as charged.

      --
      I'd give my right arm to be ambidextrous...
    45. Re:Well duh? by Danse · · Score: 1

      That being said, as a Christian, I support laws that may very well impose on others (without sacrificing freedom of religion -- again, followers should *freely* choose to believe) such as anti-abortion, protection of marriage, and other biblically-rooted legislation.

      While I can understand the conflict in the case of abortion, I certainly don't understand the issue of "protection of marriage". How does 2 men or 2 women being married make the slightest bit of difference to your own marriage? I don't see it affecting mine. I personally think that if the government is to be involved at all in marriage, it should be in the form of civil union. The paperwork side of things only. Aside from that, it's really up to the couple what rituals and terms they want to incorporate into their union. Why is it any business of yours or mine who gets married and what rituals and terms they use?

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    46. Re:Well duh? by claar · · Score: 1

      I certainly don't understand the issue of "protection of marriage". How does 2 men or 2 women being married make the slightest bit of difference to your own marriage?

      I understand why many have difficulty understanding this position. Relativism (no absolute right and wrongs in life -- only what is right and wrong for *me*) and utilitarianism (looking merely at consequences and ignoring moral principles) dominate current western ideologies. But I believe law should be "rooted in God's unchangeable character and derived from biblical principles of morality." If God's revealed law contradicts someones desired behavior, then I believe the former should dictate law -- not the latter.

      --
      I'd give my right arm to be ambidextrous...
    47. Re:Well duh? by Danse · · Score: 1

      I certainly don't understand the issue of "protection of marriage". How does 2 men or 2 women being married make the slightest bit of difference to your own marriage?

      I understand why many have difficulty understanding this position. Relativism (no absolute right and wrongs in life -- only what is right and wrong for *me*) and utilitarianism (looking merely at consequences and ignoring moral principles) dominate current western ideologies. But I believe law should be "rooted in God's unchangeable character and derived from biblical principles of morality." If God's revealed law contradicts someones desired behavior, then I believe the former should dictate law -- not the latter.

      So you're arguing for the establishment of religion by the government. Just what the world needs, another theocracy. It's all fun and games until someone with a different view than you comes along and decides that your particular interpretation of Christianity is wrong.

      People came to this country from all over to escape religious persecution and to be free to believe as they wish without the government imposing beliefs on them. Most of them were Christians who knew very well the dangers of theocratic states. Europe had seen a seemingly endless string of religious wars over the last few hundred years. Wars between different religions, and many between different sects of Christianity. They sought to prevent the government from imposing religious beliefs on people here.

      If you want to be free to worship as you choose and live as you wish, why would you be so determined to prevent others from being free to do the same, simply because they don't share your particular brand of Christianity or they adhere to some other religion or none at all?

      What if, for example, a brand of Christianity becomes dominant and decides that blood transfusions should be illegal because they violate their interpretation of scripture? Would you find that acceptable? If that happens to be your brand, I can pick another example, but hopefully you get the point. There are no absolutes, only interpretations. If there were absolutes, there wouldn't be 1000 different varieties of Christianity with various interpretations of scripture and even what should be considered scripture, all claiming to be the truth.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    48. Re:Well duh? by The+End+Of+Days · · Score: 1

      Cool, then I don't salute your bravery. All good by me.

  5. Capitalism? by Anonymous Coward · · Score: 2, Interesting

    So, would this "horizontal gene transfer" be like capitalism? Does it become a battle to see who can acquire the most and/or the best genes? Do you end up with winners for a while, until the losers get disgusted and start sparking genetic revolutions? Would Darwinian revolution be a happy meritocracy that arose as a kind of "compromise"?

    However, I've always read Darwinian evolution as "survival of the fittest", with no qualifier as to how you go about surviving. It always implied to me that the organisms (as defined by its genetic code) were what did the surviving. If organisms enhance their survival by acquiring genes through means other than sex, this doesn't seem non Darwinian to me. It just seems like a deeper understanding of evolution.

    The more intriguing possibility, with serious impliations for us humans, is "intentional evolution". In other words, organisms purposefully manipulating their own genes. That actually might be considered a radical enough change to give it a new name: Recursive Evolution.

    1. Re:Capitalism? by Chris+Burke · · Score: 4, Informative

      However, I've always read Darwinian evolution as "survival of the fittest", with no qualifier as to how you go about surviving.

      "Survival of the fittest" aka Natural Selection was half of Darwinian evolution. This was the half about how traits were selected for in the environment.

      The other half was how an organism's traits came about, and his theory was that traits were passed from parents to offspring in the reproductive cells via some biological mechanism that allowed for combination and mutation. Eventually we discovered DNA, the very biological mechanism in question that had traits like Darwin predicted (though Mendel was the one who really nailed down the probably behavior of this then-unknown mechanism).

      "Horizontal" evolution doesn't fall into that category, though. So it's not "Darwinian". Even though natural selection (obviously) still applies to what gene transfers result in successful organisms.

      As the summary mentions, this is well known in micro-organisms. In fact as far as I can tell they aren't arguing that it applies to anything but microorganisms. The argument seems more like that because these are the most common life forms on earth and also the oldest, Darwinian evolution is not the most common or dominant form of evolution.

      Which is a good point. Though really, as far as what affects us and other sexually reproducing creatures, Darwinian evolution is still 'it' more or less. The real importance of this breakthrough is in studying how the evolutionary mechanisms themselves evolved -- evolution is of course not immune to evolution. ;) This is going to be a powerful way of thinking about how early aspects of DNA came to be.

      But just to be clear -- if someone says that this proves Darwin was wrong, evolution is a sham, and therefore their beliefs are probably right, go ahead and slap them. :) All this means is that evolution is even more complicated and powerful than previously thought.

      --

      The enemies of Democracy are
    2. Re:Capitalism? by dakameleon · · Score: 1

      +5 informative here - that's probably the most succinct explanation for why this isn't Darwinian, though still could be considered evolution.

      --
      Man who leaps off cliff jumps to conclusion.
    3. Re:Capitalism? by ppanon · · Score: 3, Insightful

      Which is a good point. Though really, as far as what affects us and other sexually reproducing creatures, Darwinian evolution is still 'it' more or less. The real importance of this breakthrough is in studying how the evolutionary mechanisms themselves evolved -- evolution is of course not immune to evolution. ;) This is going to be a powerful way of thinking about how early aspects of DNA came to be.

      I'm not so sure about that. Endo-retro viruses might still be a major factor for more complex organisms and even chordates. I've been wondering about whether super-retro viruses that can cross-infect multiple species while carrying secondary genetic payloads would be a possible agent for punctuated equilibrium.

      It's interesting that there are people with varying degrees of immunity to retro-viruses like AIDS. While AIDS is not very contagious, other retroviruses could be much more easily transmitted, so you would think that retro-viral resistance would be a very beneficial and common mutation, however it appears to be quite rare. Why? Well, it's possible that such mutations have drawbacks that are more frequently a disadvantage than the immunity advantage (as a parallel, sickle-cell and Thalassemia resistance to malaria), it also might be because susceptibility to retro viruses provides a significant evolutionary advantage in the Red Queen's race for complex organisms just as horizontal DNA exchange does for bacteria.

      --
      Laissez lire, et laissez danser; ces deux amusements ne feront jamais de mal au monde. - Voltaire
    4. Re:Capitalism? by Bigjeff5 · · Score: 2, Interesting

      You read Darwin's Radio too huh?

      --
      Security is mostly a superstition... Avoiding danger is no safer in the long run than outright exposure. - Helen Keller
    5. Re:Capitalism? by ppanon · · Score: 1
      Nope, never read it. I just looked at the wikipedia synopsis and I guess there are some superficial similarities. I doubt very much that the mechanism, if it exists, would act like SHEVA in Greg Bear's novel. While Greg Bear's approach may make for a better story, it seems much less likely from an evolutionary biology standpoint.

      For starters, while they also have at least one other function, I expect that introns would be more likely to be a fault-tolerance mechanism for improving survival rates from gene insertions by retroviruses, rather than being the easily reactivated remnants of retro-viruses themselves. With introns in your DNA in addition to gene sequences, it's more likely that a random retro-viral insertion will happen at a non-critical location rather than in the middle of a critical gene sequence. Even if the introns were retro-virus remnants, it seems extremely unlikely that they would encode major genetic changes that get suddenly activated by a new virus, the same way in everyone. Why would everyone carry the same introns over millennia with no evolutionary pressure so that they could all be activated at the same time? That's X-Men comic book fluff, not biology.

      --
      Laissez lire, et laissez danser; ces deux amusements ne feront jamais de mal au monde. - Voltaire
    6. Re:Capitalism? by someone1234 · · Score: 1

      They still pass these horizontally acquired genes to their 'offspring', don't they?

      --
      Patents Drive Free Software as Hurricanes Drive Construction Industry
    7. Re:Capitalism? by mcgrew · · Score: 1

      Would Darwinian revolution be a happy meritocracy that arose as a kind of "compromise"?
      However, I've always read Darwinian evolution as "survival of the fittest", with no qualifier as to how you go about surviving.

      There is an element of luck in both capitalism and evolution, and luck probably plays a bigger part in both than fitness. Of course, obviously a bad or outmoded business plan will cause a business to fail, and a bad mutation will cause an organism to die before it can reproduce, but if there's a slow runner that doesn't get eaten by a tiger, that's pure luck. My uncle became rich, and even though he worked his ass of for it, there were a number of lucky happenstances that had to happen for him to gain his wealth.

    8. Re:Capitalism? by Chris+Burke · · Score: 1

      Indeed they do. The idea, though, is that by being able to pass the genes throughout the population without having to have one organism's offspring come to dominate and all others die out it allowed early life to find optimal organizations of genes much more rapidly. So Darwinian evolution was still happening, but this horizontal evolution was the dominant force.

      --

      The enemies of Democracy are
  6. You Need the Right Tools by Favonius+Cornelius · · Score: 2, Insightful

    I guess you could push horizontal genetic flow with viruses in the higher organisms, like us. In general however, horizontal genetic flow occurs between plants and bacteria because they have the molecular mechanisims for it. If anything it would suggest horizontal genetic flow was the first stage of evolution, with classic evolution taking over more so as time moved forward since higher organisms have a higher need to maintain genetic continuity due to specific and more complicated form. For instance you have chromosomal ploidy in plants because they follow a different evolutionary strategy: stay in place, but grow as much as possible to aquire resources. In this case genetic diversity may help. In the ambultory mammal however, it wants to retain a very specific morphology to keep doing what it does, therefore it maintains a more rigid genetic control and linear evolution.

    --
    "Men willingly believe what they wish." - Julius Caesar
  7. Once again by copponex · · Score: 5, Funny

    You know, scientists just keep reforming their ideas until it conforms to observable reality. How can they expect anyone to believe what they say when they're just going to keep changing their minds?

    I prefer my religion. It allows me to conform reality to my ideas.

    1. Re:Once again by BitZtream · · Score: 3, Insightful

      Most people treat what they call science as a religion. They go wild that someone reads a book and believes the far fetched ideas in it, yet they have no problem reading something off wikipedia and assuming its fact.

      The claim is that you CAN test and confirm it, but they don't, they just blindly assume because someone else wrote it down and some others agree with them.

      I really don't see any difference in the way most nutjobs treat science compared/contrasted to the way religions nutjobs treat religion.

      --
      Persistent Volume manager for Kubernetes - https://github.com/dwimsey/openshift-pvmanager
    2. Re:Once again by SoftwareArtist · · Score: 1

      Yep, there's a big difference between "science" (what scientists do, a process for studying the universe) and "Science(TM)" (a religion based on believing a large body of doctrine without having a clear understanding of what evidence that doctrine is based on). It doesn't help that many of the "science reporters" for the news media don't have a clear understanding of the difference.

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
    3. Re:Once again by Opportunist · · Score: 1

      You conform reality to your ideas? You change reality by the power of your will?

      Yo're practicing witchcraft! WITCH! BURN IT!

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    4. Re:Once again by Cassius+Corodes · · Score: 4, Insightful

      The basic problem is that you don't have infinite time, and as such you have to 'outsource' your knowledge gathering to other people. The problem then becomes one of who do you trust? If you use a heuristic of who has got good results in the past and that leads you to 'blindly' believe in the brand of science - well I can't really find any fault with that. As a researcher, while I know lots about my area, I don't know jack about others so I blindly trust what my doctor, mathematician, physicist tell me. If its an issue of importance I get a second opinion from another doctor etc, but at the end of the day I am blindly trusting them. I don't think there is anything wrong with that.

      --
      Control is an illusion, order our comforting lie. From chaos, through chaos, into chaos we fly
    5. Re:Once again by phliar · · Score: 3, Insightful

      It's not quite 'blind' trust, though. It is reasonable trust, because we've seen that in the past, the methods and models those guys talked about have actually been verified. They invented electronic things that have had a profound effect on humanity. History tells us modern medicine has improved human health immensely (if you're rich enough, of course). And I (an ex-researcher) do know how the scientific method works and what its limitations are. Therefore my "belief" in science is reasonable.

      The best part is that it works for you even if you don't believe in it -- so creationists can still enjoy the fruits of science. Science is better.

      --
      Unlimited growth == Cancer.
    6. Re:Once again by Thaidog · · Score: 1

      But they're not really your ideas are they? I mean, unless you invented the religion chances are you've just have a "time share" on your beliefs.... and I hate timeshares.

      --

      ||| I still can't believe Parkay's not butter.

    7. Re:Once again by repapetilto · · Score: 1

      The problem is that it takes so much specialized knowledge to be able to really judge how a scientist has interpreted their data due to all the background info needed to take it in the correct context. But thats just how it is... the world is complex... you arent going to get anything more than a superficial understanding of what goes on inside cells from an NPR episode because you have to consider the model (in vitro... cell type, buffer, concentrations of various ions, source of the cells, etc) or in vivo (what did they have to do to manipulate the organism to have to study it, what other systems are regulating that one, possibly vice versa at the same time...) My point is to really know whats going on take specialized knowledge that you just cant incorperate into your worldview properly by reading one article plus looking up what you dont know at wikipedia/google/whatever. It really is literally impossible to explain it fully to someone in a time period measured in less than years. People have other things to do and need to sleep to consolidate the knowledge.

    8. Re:Once again by mcgrew · · Score: 1

      History tells us modern medicine has improved human health immensely (if you're rich enough, of course).

      Or if your country's national religion isn't capitalism. Most developed nations do in fact have health care available to all, regardless of wealth, unlike mine.

  8. I dunno... by Dupple · · Score: 5, Funny

    I pass on my genes horizontally

    --
    Watch those corners
    1. Re:I dunno... by girlintraining · · Score: 1

      I pass on my genes horizontally

      Roses are red, genes are blue,
      their mistakes are small, and very rare,
      as long as you discount, Dupple's hair.
      *cough*
      Anyway, I don't care what's in your genes as long as you stay out of mine. :P

      --
      #fuckbeta #iamslashdot #dicemustdie
  9. Genetic Engineering by ddxexex · · Score: 3, Insightful

    So does this explain why you can stick "random" genes into a completely different organism and gain traits that wouldn't arise normally? This seems like it'll be very useful in GE if the mechanics of it are explored more.

    1. Re:Genetic Engineering by timmarhy · · Score: 1

      actually that's a myth, you can't just stick random genes into any organism and have it survive. it's one of the nonsense arguments the anti GM fanatics spout while they foam at the mouth about so called frankenfood.

      --
      If you mod me down, I will become more powerful than you can imagine....
    2. Re:Genetic Engineering by DragonWriter · · Score: 2, Insightful

      So does this explain why you can stick "random" genes into a completely different organism and gain traits that wouldn't arise normally? This seems like it'll be very useful in GE if the mechanics of it are explored more.

      Well, except that the mechanisms involved in horizontal gene transfer are already key tools in genetic engineering. The notionally big deal here is the idea that because of the dominance of horizontal gene transfer as a primary mechanism of gene transfer, there was a time when organism-centered evolution wasn't the primary mode of evolution, and that instead the units on which evolution operated were genes themselves. The case has been made previously (and popularized by Richard Dawkins in The Selfish Gene) that while organisms are convenient proxies in lots of cases, genes ought to be considered the unit on which selection works even now, and that doing so was both more practically useful and more sensible in terms of the logical coherence of the model than using the organism as the fundamental unit on which evolution works.

      In any case, it may be a mistake to contrast this with "Darwinian evolution" particularly in the "modern sense", since Darwinian evolution is recognized as a general process which applies when certain factors are present, no matter what the unit on which it works happens to be (and this generality is important to its applications in machine learning and is at the heart of the concept of memetics.)

    3. Re:Genetic Engineering by fusellovirus · · Score: 1

      You can order a kit to do just that http://www.epibio.com/item.asp?ID=291 the kit is based on a naturally occuring DNA sequence called a transposon http://en.wikipedia.org/wiki/Transposon that can cut out and splice in DNA allowing it to move around the genome

  10. It's still natural selection by BenBoy · · Score: 4, Insightful

    This really isn't entirely new; Dawkins' book The Selfish Gene is based around the idea that it's individual genes that are selected for, not organisms.

    1. Re:It's still natural selection by phantomfive · · Score: 3, Informative

      Which is nothing more than a restatement of what Darwin said, since a gene is nothing more than an encoded trait. It is the trait that actually matters, not the gene, since the trait is what gives the animal the ability to survive. It doesn't really matter if the trait is encoded as DNA or as biologic etchings on advanced carbon fiber, in either case it is just a representation of a trait.

      --
      Qxe4
    2. Re:It's still natural selection by Locke2005 · · Score: 3, Interesting

      In social animals, it is the survival of the group that is driving evolution, not the survival of individual or their genes. If the survival of each individual's genes were paramount, there would be no homosexuality and no parents killing their own children, 'cause those are pretty much dead-end paths from the standpoint of survival of the individual. Another way of thinking of this is that altruism really does have survival value; just like with army ants, being willing to sacrifice individuals for the good of the group is a good evolutionary strategy.

      --
      I've abandoned my search for truth; now I'm just looking for some useful delusions.
    3. Re:It's still natural selection by timmarhy · · Score: 1

      and what causes them to be social animals? their genetics. no amount of environmental factors is going to cause say, a great white shark, to suddenly become a social animal.

      --
      If you mod me down, I will become more powerful than you can imagine....
    4. Re:It's still natural selection by Trepidity · · Score: 1

      In a broad sense, yes, but in a more specific sense, Darwinian evolution, which posits inheritance by natural selection of traits, is often contrasted with Lamarckian evolution, which posits inheritance of adult traits. Horizontal gene transfer is not quite Lamarckian evolution (it's not usually from parents to children), but in the sense that traits acquired in adulthood can be passed on, it's closer to Lamarckian than Darwinian evolution.

    5. Re:It's still natural selection by franoreilly · · Score: 1

      There's nothing fundamentally different being mooted here.

      We are talking about the very early stages of life when I imagine that the boundary between separate organisms itself was probably very poorly defined compared to today's life forms; so in that sort of environment, a different horizontal mechanism of gene propagation could well have been the primary one.

      The mechanism may be somewhat different to most of what happens today, but the core concept of Dawkins' "selfish gene" is unchanged, where the propagation of the gene, not the type of organism, is selected for,

      --
      -- --- Learn language vocabulary with mnemonics: http://www.memorista.com
    6. Re:It's still natural selection by feepness · · Score: 1

      In social animals, it is the survival of the group that is driving evolution, not the survival of individual or their genes.

      The question then becomes... which group.

    7. Re:It's still natural selection by phantomfive · · Score: 1

      What you say is accurate, but you seem to have missed the context, since in my post I was referring to Dawkin's Selfish Gene idea that the GGP was referring to, not so much the idea of horizontal gene transfer.

      Referring back to the content of your post, you are right, but to be fair to Darwin, I don't think he really addressed the evolution of microscopic organisms.

      --
      Qxe4
    8. Re:It's still natural selection by trouser · · Score: 3, Informative

      Not the individual's genes, the individual gene. In all plants and animals it is reproduction combined with mutation and recombination that is driving evolution.

      Social animals posses genetic traits which promote social or herd behaviour. In these animals the trait survives because for these animals in the environment in which the trait emerged it increases the chance of survival and reproduction. The gene promotes itself.

      Worker ants are infertile. They share common genetic information with the queen. To protect the nest and the queen increases the chance of propagation of their genes even though they do not reproduce themselves. There's probably a gene for that.

      I have no idea about infanticide but I do recall hearing of a study recently which observed that homosexual men frequently have one or more close female relatives who are unusually fecund. I can't find the link and the research may have since been debunked but the idea is interesting as it suggests the possibility of a gene which increases the reproductive fitness of one individual while reducing the reproductive fitness of another.

      Of course that assumes that being homosexual reduces your chance of reproduction.

      --
      Now wash your hands.
    9. Re:It's still natural selection by SoftwareArtist · · Score: 3, Informative

      Exactly. Evolution is a fundamental mathematical process that applies to information, not organisms. To get evolution, you only need two elements:

      1. An information storage medium.

      2. A mechanism for reproducing that information such that certain pieces of information are more likely to get reproduced than others.

      Once you have those, everything else follows, and it doesn't matter what the precise storage mechanism or copying mechanism is. Horizontal gene transfer is just another way for genetic information to reproduce.

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
    10. Re:It's still natural selection by Anonymous Coward · · Score: 0

      Not entirely true.

      Take for instance, Honey Bees.

      They pretty much *ALL* have an endemic strain of Wolbachia parasite infesting them. It's what causes them to all be female.

      http://www.culturaapicola.com.ar/apuntes/revistaselectronicas/apidologie/34-1/06.pdf

      Contrast this with solitary bees and wasps, which act VERY differently when they are exposed to Wolbachia.

      http://www.sccs.swarthmore.edu/users/99/mahowald/hymenoptera.html

      Essentially, once exposed to the parasite, males become EXTREMELY rare, and so the solitary behavior of the organism, and "Normal" sexuality (1:1 pairings) become a disadvantage to survival of the species.

      This is an example of an environmental (Wolbachia infection) pressure radically changing the social behavior of a whole genera of species, with a strong selective pressure to become social hive groups rather than solitary breeding individuals for survival.

      Thus, your argument that "Nothing can make a great white shark social" is not exactly true. All it needs is selective environmental pressure that causes de-facto selection for that trait.

    11. Re:It's still natural selection by kungfugleek · · Score: 1

      I've always thought altruism is when one person sacrifices oneself; not when a society chooses which ones get sacrificed.

    12. Re:It's still natural selection by Anonymous Coward · · Score: 0

      This is a common misconception, there is no group selection in current evolutionary theory. Altruism is not valuable for the individual because there is only one copy of each, but it's valuable for a gene because it might be copied several times in other individuals. In other words, when you sacrifice yourself to save 8 of your cousins you might be saving an average of 2 copies of your genes, which is all natural selection cares about. It's still survival of the fittest gene, not of one particular copy of the gene, but of the gene as a unit of information that can be replicated in several individuals.

    13. Re:It's still natural selection by Anonymous Coward · · Score: 0

      Worker ants are infertile. They share common genetic information with the queen. To protect the nest and the queen increases the chance of propagation of their genes even though they do not reproduce themselves.

      I hear this is also quite common among iPhone users.

      There's probably a gene for that.

      Ah, that explains it.

    14. Re:It's still natural selection by kpesler · · Score: 1

      This research is not about the trait itself, but the topology of transfer. Darwinian evolution admits two major processes: random mutation and natural selection through survival of offspring. In other words, genes are transferred only vertically, from parent to offspring. The authors showed through simulation that this Darwinian mechanism alone cannot explain the universality of the code itself or its error-correcting properties. If one takes into account horizontal gene transfer, i.e. direct exchange of genetic material between members of the same generation, these properties themselves are the natural product of evolution. They further assert that in the early stages of evolution, this horizontal transfer was dominant over the vertical. As complexity grew and biological pathways became more sensitive, horizontal transfer became more likely a hindrance than a help, and vertical transfer became dominant. The article is worth a read and states this much more clearly than my terse summary.

    15. Re:It's still natural selection by Anonymous Coward · · Score: 0

      You've missed the point. Even if a gene doesn't code for any proteins, and has no affect on the traits of the organism it's in, it can still evolve, competing against other genes. It may have a funny affinity for DNA polymerase that causes additional copies of it to be made when the DNA is duplicated; or it may contain sequences that attract the attention of restriction enzymes, causing some copies of it to be sliced free and ejected from the cell, occasionally to be picked up and replicated by the cells of other organisms. All of this has no bearing on the traits of the organism - it's the traits of the gene (how it interacts with various enzymes, etc) that determine its fitness in this respect.

      I could make an argument, similar to yours, that the traits of individual organisms don't matter - that it's the way they influence the characteristics of a group (herd, flock, whatever) of similar animals that is significant. After all, that's what gives a group of animals its ability to survive, and allows it to compete with other groups in the same niche, possibly splitting into two groups (prides, gaggles, whatever) if it is sufficiently successful. This is accurate only when there is no flow of animals or genes between these groups; in the same way as the conventional Darwinian view of evolution, as competition between animals, is valid only when there is no flow of genes between those animals. That's a good approximation for macroscopic life (elephants, us, etc), but it's less good as a description of bacterial evolution, and as the article points out (in a horribly journalistic fashion), it's even worse for describing the development of the earliest life.

    16. Re:It's still natural selection by Starker_Kull · · Score: 2, Informative

      If the survival of each individual's genes were paramount, there would be no homosexuality and no parents killing their own children, 'cause those are pretty much dead-end paths from the standpoint of survival of the individual.

      You just missed the flaw in your reasoning - you confuse an individual's GENES with the INDIVIDUAL. Consider that a parent only has 50% of their genes in a child; if it turns out that killing the child would allow for the opportunity to invest more in other children, and increase their probability of having offspring (i.e. getting more copies of your genes in circulation), it might be very RATIONAL to kill your own child from the standpoint of increasing the frequency of your genes in the population. This behavior is observed frequently in animal species besides man. Consider how violently men react to adulterous women and thier offspring - the possibility that they might have been investing resources in a child with 0% of their genes means they have nothing to lose, genetically, by offing them. The math of kin selection has been worked out quite precisely, in many different species with different mating habits, and the numbers work out; we (as in man and virtually every other species) tend to behave in such a way as to maximize the spread of our genes, regardless of whether the copies come from us or from our kin.

      You mention ants - ants behave the way they do because of the highly unusual way they pass genes on - or should I say, the way most ants DON'T. In a given colony, all the future ants (and future genes) come from the queen, who has sex briefly (for a day or two) with between 1 and 10 males, and stores their sperm to produce eggs for the rest of her life. The reason so many ants work themselves to death, engage in combat to the death to protect the queen, and in general seem to not care for themselves as individuals, is they are, as individual reproducers, done. The only chance they have for enhancing the odds of their GENES being spread is by doing everything possible to protect and nuture the only possible reproducer of those genes - the queen. And guess what - the genes that influence aunt behavior in that way are the ones that have been the most successful.

      Group level selection has very little evidence going for it, although in highly advanced creatures (like us), it may play a greater role than in general. You should read The Selfish Gene, and The Extended Phenotype, by Dawkins, to see the arguments about group vs. individual vs. genetic selection really hashed out in detail.

    17. Re:It's still natural selection by timmarhy · · Score: 1

      I guess, I only considered external factors and not a total change in the animals physiology.

      --
      If you mod me down, I will become more powerful than you can imagine....
    18. Re:It's still natural selection by zarzu · · Score: 1

      how is horizontal gene transfer in any way lamarckian? it's still genes that are being transfered and genes don't change when you acquire new traits in your lifetime. this has absolutely nothing to do with lamarckism.

    19. Re:It's still natural selection by mcgrew · · Score: 1

      Of course that assumes that being homosexual reduces your chance of reproduction.

      I don't see how it wouldn't. One has to be attracted to the opposite sex (and be attractive to them) to reproduce.

    20. Re:It's still natural selection by Anonymous Coward · · Score: 0

      And guess what - the genes that influence aunt behavior in that way are the ones that have been the most successful.

      Hey I have an aunt that doesn't reproduce either. While I know she'd do a lot to help my mother or myself in a bad situation, I doubt she'd be willing to work herself to death...

    21. Re:It's still natural selection by trouser · · Score: 1

      In our ancestral evolutionary environment being attracted to one another, dinner and a show, consent, etc. may not have been high on the agenda.

      --
      Now wash your hands.
    22. Re:It's still natural selection by Vadim+Grinshpun · · Score: 1

      Not quite. It's a different way of thinking about the same thing.
      As best as I remember "The Selfish Gene", it does present the gene as the unit of selection. The organism is discussed more as a just a useful vehicle (which exists due to multiple genes working to a common effect, but only because there's an advantage on the individual gene's level). I'm simplifying, but that's the gist of it.
      If you didn't get a chance to read the book yet, try it. Interesting stuff.

  11. It's what's for dinner. by mrmeval · · Score: 3, Insightful

    I am going to come over there and take all your stuff and I'm going to kill you and take your weapons and use them for myself!!!

    If you're really nice and sweet I'll beat the crap out of you and then stick you in my kitchen to make food for me.

    The second is referring to mitochondria not kitchen bitches.

    --
    I'd go on a Vegan diet but the delivery time from Vega is too long. --brownkitty
    1. Re:It's what's for dinner. by Anonymous Coward · · Score: 0

      Mmmmm, kitchen bitches.

    2. Re:It's what's for dinner. by nacturation · · Score: 1

      The second is referring to mitochondria not kitchen bitches.

      Where do the midichlorians come into play?

      --
      Want to improve your Karma? Instead of "Post Anonymously", try the "Post Humously" option.
    3. Re:It's what's for dinner. by Opportunist · · Score: 2, Funny

      Usually after the good movies are done and you want to milk the franchise some more.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    4. Re:It's what's for dinner. by aqk · · Score: 0

      Sounds good.

      Can you bring a bottle of Pinot?
      I promise. We'll just watch PBS. Or whatever you want, big boy. I'm easy.




      And I do make a magnificent Fettucini Vongole!

    5. Re:It's what's for dinner. by mrmeval · · Score: 1

      And they tug on the wrong tube.

      --
      I'd go on a Vegan diet but the delivery time from Vega is too long. --brownkitty
    6. Re:It's what's for dinner. by stifler9999 · · Score: 1

      But the Mitochlorides in me will win, Obi Wan.

    7. Re:It's what's for dinner. by stifler9999 · · Score: 1

      Its a ZZ9 Plural Alpha thing, here on earth - its plural.

  12. If you want to do the cross-species thing . . . by StefanJ · · Score: 4, Funny

    . . . you're better off doing it vertically.

    Wearing running shoes.

    And ideally permission of the farmer.

    (beat)

    What?

    1. Re:If you want to do the cross-species thing . . . by Anonymous Coward · · Score: 0

      But there is another way for doing the cross species thing:
      last time I did the horizontal gene-transfer I received some genes of a different species in return...
      now I am taking antibiotics hoping to get rid of it...

    2. Re:If you want to do the cross-species thing . . . by fredrik70 · · Score: 1

      sorry, why the running shoes??

      --
      if (!signature) { throw std::runtime_error("No sig!"); }
  13. Still natural selection by Toonol · · Score: 3, Informative

    We've already known that evolution depends on both inheritance of genetic matter and mutation of genetic matter. This is a third mechanism for generating traits, but it stills falls under the umbrella of natural selection. If the change is beneficial, and leads to more offspring, the change will be selected for. Certainly worth study, and we may not have known the full scope of the phenomena, but it doesn't really contradict Darwinian evolution at all.

    As a side note... I wonder if the fact this occurs in nature will silence some of the people objecting to genetic splicing?

    1. Re:Still natural selection by Trepidity · · Score: 2, Insightful

      Well, it's a mechanism for directly passing on traits (via a direct transfer), which is closer to Lamarckian evolution than Darwinian evolution, in the classic 19th-century dispute. But you're right that it's not a huge challenge to modern evolutionary theory. What it might pose somewhat more of a problem for are certain areas of phylogenetics, especially cladistics that rely fairly heavily on an assumption that evolutionary trees are indeed trees.

    2. Re:Still natural selection by MrMr · · Score: 1

      I find it surprising that the auhors seem to think that Darwinian selection only happens to organisms, but not to the genes that are being spliced.
      Perhaps the only paradigm they need to shift is their misconception of what exactly evolves in evolution.

  14. I've suspected this all along by Locke2005 · · Score: 1

    I've always felt that viruses might be the driving force in evolution; they are very good at taking genes from one organism and splicing them into another. Also, one of the first traits that would have evolved after the split into two sexes would have been the ability to choose mates with traits complementary to your own, thus for higher species there is actually some intelligence driving evolution forward.

    --
    I've abandoned my search for truth; now I'm just looking for some useful delusions.
  15. I've heard of this by Beerdood · · Score: 0

    From TFA : Suppose that a process he never wrote about, and never even imagined, has been controlling the evolution of life throughout most of the Earth's history

    Intelligent Design?

    --
    Global warming and other natural disasters are a direct effect of the shrinking number of pirates - Gospel of the FSM
    1. Re:I've heard of this by AP31R0N · · Score: 1

      Bevets? Is that you?

      --
      Utilizing the synergization of benchmark e-solutions to pre-workaround action items!
  16. Only horizontally? How quaint by Animaether · · Score: 1

    You're not nearly adventurous enough, young lad!

    Then again.. I've always thought the guy who's getting it on standing upright in his Corvette convertible is destined for a Darwin Award, so there might be something to this story

    1. Re:Only horizontally? How quaint by Anonymous Coward · · Score: 0

      Sorry for my ignorance, but how do you best perform vertically after the application of chloroform? Would I need to employ copious amounts of rope and such.

  17. Bestiality? by Anonymous Coward · · Score: 0

    Cross-species genetic transfer? Like on Avatar, right?

  18. You raise an interesting point here by Xaedalus · · Score: 1, Insightful

    One of the issues I've been thinking a lot about lately is the psychological principle of certainty. When you say "...scientists just keep reforming their ideas until it conforms to observable reality. How can they expect anyone to believe what they say when they're just going to keep changing their minds?" you hit upon something important: certainty of belief. How can the average layperson trust scientific opinion when said scientific opinion says "This is FACT... until it's not"? People require certainty of belief in order to operate. They have to know that gravity means you're pulled down, the sun will rise in the east, that the Bernoulli theorem will always work when they're flying. They incorporate these facts into their daily operation and worldview.

    So when scientists say "X is true" and then come along several years later and say "No, we were wrong, Y is true" and then come along several years alter and say "Both X and Y were wrong, now Z is true", the average person cannot count on the certainty of X, Y, or Z, or that the scientists are correct. Regardless of the fact that most citizens are taught the scientific process in school, most of them don't retain it because it has little to no impact on their daily lives (they take for granted the progress we've made). And thus, we get people who deny global climate change, or that we walked on the moon, or that vaccines work.

    Here on /., we all argue over these topics and for the most part, we understand the scientific process (whether we agree with its findings is a whole other story). We may argue, fight, and haggle, but eventually we do reach a consensus. However, the average citizen never does, and I think that's why we have so much skepticism towards evolution, or climate change, or space flight, or vaccines, or science in general, and why so many choose to cling to organized religion (Up until Vatican II for instance, Catholic dogma had not changed much since the seventh century - that's pretty damn static).

    I hope you don't mind me airing my opinion here. I just thought you raised a really interesting point and wanted to call some attention to it. We on /. tend to forget that most of the world's population has no idea what Science is: to them, scientific progress is indistinguishable from magic.

    --
    Here's to hot beer, cold women, and Glaswegian kisses for all.
    1. Re:You raise an interesting point here by Joel+Brown · · Score: 3, Insightful

      It is important to note that the idea the "science is about truth" is a common intellectual error of modern society. Science has nothing to do with finding truth or learning how the universe actually works or anything of the sort. Science is about building models of observable natural phenomena. The point of the models is to conform with what is observable and hopefully predict something that hasn't yet been observed, but which can then be tested and seen to work. Good science is about building models that work well, and refining models that don't. Poor science is about building models that sound like they ought to work but don't conform to observation. Really lousy science is about building models that can't be tested against reality and don't predict anything. Are you listening evolutionary psychologists? Take for example: "survival of the fittest" - This is a model for the mechanism by which one organism gets to spread its genes. It sounds perfectly plausible, almost indisputably sensible. But what does it mean? The key is the word "fittest". "Fittest" means best able to survive. So the model mechanism is really survival of the one ones that survived. Now it sounds trite and unhelpful, which it is. How do we know it's not "survival of the luckiest" or "survival of every n-th one"? We don't, but survival of the fittest is more appealing to our cultural sensibilities, so we go with that. If you remember that science is about coming up with ways to get your head around nature, rather than about figuring out what nature really is, then you don't get caught in the trap of "how can you trust science?" You only have to trust it as far as it is working for you, you don't have to build your world view on it.

    2. Re:You raise an interesting point here by Opyros · · Score: 1

      Oh noes! Them pointy-headed scientists have discovered that the Bernoulli effect isn't (entirely) what keeps an airplane in the air! Now we're all going to die the next time we fly!!!U+203C!!!

    3. Re:You raise an interesting point here by Anonymous Coward · · Score: 0

      A: "Here's a picture of a galaxy."

      A: "Oh no, -- that was distorted -- here's a sharper picture of the galaxy."

      A: "Oh no, -- that was distorted -- here's an even sharper picture of the galaxy!"

      B: "Bullshit man, bullshit! You keep changing the picture, man! How can I believe a thing you're saying?!?"

    4. Re:You raise an interesting point here by Opportunist · · Score: 4, Interesting

      Science is not the search for "truth". It's the search for an explanation. Unfortunately, it has become the new religion, people simply believe what some scientist says as gospel and, as you identified, are then frustrated and irritated if it is found to be incomplete or utterly false.

      That is not how science is to be treated. Science does not have all the answers. Science is the search for those answers, not the answer itself. Science is not about believing, it is about doubting. About offering a theory and offering ways to test that theory. Especially the latter part is often overlooked by people. A good theory offers an angle to falsify it. I may state that at the center of a black hole is cake. Just to make all the Portal players happy. And while we're at it, before the big bang there was a flat world carried by a turtle. You cannot falsify either theory. You cannot test them. So they have to be true. Right? False! Both are non-theories. They have zero scientific value. At least until we somehow find ways to test them.

      So presenting any theory that offers no vector of testing is, scientifically, worthless. Unfortunately, that's not easy to convey to people. They want explanations. And science cannot offer them. Science is not about certain answers. It is about questioning theories.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    5. Re:You raise an interesting point here by Anonymous Coward · · Score: 0

      So when scientists say "X is true" and then come along several years later and say "No, we were wrong, Y is true" and then come along several years alter and say "Both X and Y were wrong, now Z is true", the average person cannot count on the certainty of X, Y, or Z, or that the scientists are correct.

      The great thing about science, though, is that the new theory still has to be consistent with the the evidence that produced the last one. For example, way back when, scientists said "the world is flat", and then several years later said "No, we were wrong, the world is a sphere". But because the sphere is so large, any person who confined themself to a space the size of a village/city could act as though the world were flat and they wouldn't get any noticable error if they were measuring anything. Then several years after that scientists come along and say "The world is not flat, and not a sphere, it's slightly compressed at the poles". Although the last two theories are "wrong", you can use them as approximations to the truth.

    6. Re:You raise an interesting point here by npsimons · · Score: 0, Redundant

      I may state that at the center of a black hole is cake. Just to make all the Portal players happy.

      THE CAKE IS A . . . naw, too easy. Besides, I really should get back to work. I mean, here I am still talking when there's science to do. It may be frustrating at times, but there's no sense crying over every mistake.

    7. Re:You raise an interesting point here by Artifakt · · Score: 1

      You're making a seldom stressed point: usually, it's mentioned how people in more primitive times wanted certainty so they coined such things as religions - seldom does anyone point out that modern lifestyles are a powerful motivator for people to put at least as great a premium on certainty as any peasant of the middle ages felt.

      Roman Catholic dogma doesn't really date back to the 7th century though. There's certainly some truth to that view, often an uncomfortable lot for many modern Catholics from what I've seen, but a lot of dogma got locked into place only during the counter-reformation (Council of Trent 1545-1563 a.d.), and not earlier. For a couple of other exceptions, one of the big reasons for the formation of the Anglican church (aside from Henry VIII's ego) was that St. Patrick of Irish fame was a Bishop in the 5th century and most of his writings were overidden by Roman Catholic councils made up entirely of Italian clergy about the 10th century, in ways that arguably meant Patrick was both a saint and a figure whose actual opinions were mostly considered heretical. A second exception is priestly celibacy, which only became fixed doctrine about 300 years after the point you are describing as pretty damned static.

      For a lot of people who are theoretically educated enough to see the differences between science itself and magic, the problem is that progress (scientific progress or plain old progress) is seen as part of something that works like magic (and like magic in fantasy novels), or technology and science are seen as interchangeable.

      --
      Who is John Cabal?
    8. Re:You raise an interesting point here by johanatan · · Score: 1

      Perhaps scientists would be well served to, instead of stating "X is true", to rather state that "X appears to be true given the empirical evidence we currently have with Y% degree of certainty"?

    9. Re:You raise an interesting point here by repapetilto · · Score: 1

      That is exactly what happens... You dont get that if you only read news articles about it though. If theres one thing that sets science apart in figuring out the world around us its that noone really trusts anyone else. Not because theyre necessarily trying to be misleading but because all the experts know theres 1000 factors coming into play and noone can ever get rid of all the confounds and dose-response and timecourse issues and still get paid since it would cost too much. If youre figuring out fundamentals that might work but not these days.

  19. Original paper on arXiv by PaulBu · · Score: 5, Informative

    For those who do not care to register for that New Scientist, we still have arXiv... :)

    http://arxiv.org/abs/q-bio/0702015

    Paul B.

    1. Re:Original paper on arXiv by radtea · · Score: 4, Informative

      Thanks, as the New Sensationalist article is full of lies and hyperbole, completely idiotic, transparent falsehoods like, "This code is universal, shared by all organisms, and biologists have long known that it has remarkable properties"

      This simply a lie, as is the claim that 64 combinations producing 20 codons is "redundancy". The reason there are only 20 is well-known to anyone with the least little bit of familiarity with the subject: it is the maximum number of unambiguous combinations, so that if you get six bases in a row there is exactly one way to read them, because no two codons together can result in a third codon being read between them.

      The arXiv article may have something interesting to say, although inter-species genetic transfer has been known to occur amongst micro-organisms for a long time. From a Darwinian perspective the genes available in the environment are just that: another perfectly ordinary part of the environment. Since Darwin's Law depends only on the laws of probability and the fact of imperfect replication, it applies to situations where horizontal transfer takes place just as much as when imperfect copies of genes come from ancestors.

      The details of Darwinian evolution will change a little in the context where organisms are taking genetic resources directly from the environment, but it's still a Darwinian process.

      The weird statements about "questioning if organisms even exist as individuals" are just idiotic marketing hype that pretty much ensure the whole argument is vastly less interesting and important than the authors want to make it appear. Otherwise, why the need for such anti-scientific hype? Unless it is the New Sensationalist characteristically ripping an innocent statement out of context.

      --
      Blasphemy is a human right. Blasphemophobia kills.
    2. Re:Original paper on arXiv by radtea · · Score: 3, Interesting

      http://arxiv.org/abs/q-bio/0702015 [arxiv.org]

      Ok, I've read the original paper now, and it is almost as moronic as the New Sensationalist makes it out to be.

      Their argument is analogous to the following claim:

      I can stand on dry land, or I can swim in the water, but there is the broad swath of territory that is neither dry land nor water so deep I can do nothing but swim in it. Therefore, the concept of "land" (or "water") may actually be completely useless! Aren't we clever?

      Scientists have a tendency toward various kinds of conceptual realism, where they think that there is exactly one way to properly understand the universe, and the entities picked out by that way are "real" and no others are. When they find a case that they can't crisply classify under the existing concepts there are two moves: the smart one, that refines existing concepts and introduces new ones to deal with the boundary cases; and the idiotic one, that claims that since the existing concepts don't deal well with the new case, they must not pick out anything "real" after all and should be thrown away.

      That the biological species concept fails in various ways has been known for a long time. They are now pointing out that certain criteria that would normally be used to delineate individuals might also fail under some circumstances. To this I say: big deal. The biological species concept, like the concept of Newtonian mass, is still incredibly useful in understanding reality under a wide range of circumstances, which is all a scientist can hope for. If their new concepts--which they don't really offer--transform smoothly into the biological species concept in the appropriate circumstances I'll be interested. Otherwise, they're just gabbling.

      --
      Blasphemy is a human right. Blasphemophobia kills.
    3. Re:Original paper on arXiv by rgmoore · · Score: 4, Interesting

      This simply a lie, as is the claim that 64 combinations producing 20 codons is "redundancy". The reason there are only 20 is well-known to anyone with the least little bit of familiarity with the subject: it is the maximum number of unambiguous combinations, so that if you get six bases in a row there is exactly one way to read them, because no two codons together can result in a third codon being read between them.

      Except that isn't true. Every one of the 64 possible 3 base sequences is a valid code for either an amino acid or a stop codon. Some viruses take advantage of this by overlapping protein coding regions, with different proteins being coded by reading in different frames. In eukaryotes, there are some genes that can code for proteins with very different sequence regions because an exon skipping splice variant results in a frame shift that codes for a completely different sequence.

      A more significant complaint about the "This code is universal, shared by all organisms" quote is that it isn't universal. There are small differences in the genetic code between genomes. NCBI lists no fewer than 23 different versions, but given that a tiny fraction of all species have been studied there are undoubtedly many more minor variants. An especially interesting case- and the place that difference in genetic codes were first discovered- is that human nuclear and mitochondrial sequences use slightly different genetic codes. The mitochondria even have their own distinct ribosomes.

      --

      There's no point in questioning authority if you aren't going to listen to the answers.

    4. Re:Original paper on arXiv by Ginger+Unicorn · · Score: 1

      New Scientist is absolutely awful for giving creationists ripe quote mines by presenting every new discovery or refinement to biology as somehow rendering all previous discoveries a bunch of naive speculation, and banging on about "darwin" being "wrong". This article is an egregious example, giving up juicy quote mines like:

      How could modern biology have gone so badly off track? According to Woese, it is a simple tale of scientific complacency.[...]Woese believes that along the way biologists were seduced by their own success into thinking they had found the final truth[...] "Biology built up a facade of mathematics around the juxtaposition of Mendelian genetics with Darwinism," he says.

      Strong claims, but others are taking them seriously. "Their arguments make sense and their conclusion is very important," says biologist Jan Sapp of York University in Toronto, Canada. "The process of evolution just isn't what most evolutionary biologists think it is."

      nothing in the modern synthesis explains the most fundamental steps in early life: how evolution could have produced the genetic code and the basic genetic machinery used by all organisms, especially the enzymes and structures involved in translating genetic information into proteins. Most biologists, following Francis Crick, simply supposed that these were uninformative "accidents of history".

      Evidence for this lies in the genetic code, say Woese and Goldenfeld. Though it was discovered in the 1960s, no one had been able to explain how evolution could have made it so exquisitely tuned to resisting errors. Mutations happen in DNA coding all the time, and yet the proteins it produces often remain unaffected by these glitches. Darwinian evolution simply cannot explain how such a code could arise.

      In 1991, geneticists David Haig and Lawrence Hurst at the University of Oxford went further, showing that the code's level of error tolerance is truly remarkable.[...]"The actual genetic code," says Goldenfeld, "stands out like a sore thumb as being the best possible." That would seem to demand some evolutionary explanation. Yet, until now, no one has found one.

      If a paradigm shift is pending, Pace says it will be in good hands. "I think Woese has done more for biology writ large than any biologist in history, including Darwin," he says. "There's a lot more to learn, and he's been interpreting the emerging story brilliantly."

      --
      (1.21 gigawatts) / (88 miles per hour) = 30 757 874 newtons
  20. I wrote about this a while ago by presidenteloco · · Score: 3, Interesting

    The notion that life probably started by weak, stochastic replication of families of similar molecules.

    By weak, is meant that the replication of the molecule/structure is more imperfect from generation to generation
    than in present day life, and so a class of similar molecules (life codes) is being continued through time
    rather than a singular particular molecule (same genome).

    If this origin theory were true, we would expect the replication capability (continued recreation of imperfect but still somewhat replication-capable molecules)
    to be robust to change of DNA/RNA even today.

    By stochastic, is meant that such imperfect replication is likely to only be stochastically successful in a huge population of the
    initially highly approximate (i.e. weak) replicator molecules.

    In other words, we would not expect this proto-life to be as reliable at being able to continue (or to always reliably grow by recruiting
    surrounding matter into high-fidelity copies.)

    So we might expect these proto-life molecule soups to initially just contain in some regions higher than expected probabilities,
    stochastically, from time to time, of weak-replicator molecule classes.

    Perhaps there is a binary threshold of replication probability and fidelity at which the process self-sustains reliably in the
    generality of environment it finds itself in. Life catches fire, and cannot easily be stopped at its matter and energy recruitment
    game from that point on.

    --

    Where are we going and why are we in a handbasket?
  21. So how does the FSM fit into all of this? by davidwr · · Score: 1

    I mean, explain this.

    --
    Knowledge is how to play a game, intelligence is how to win, wisdom is knowing what game to play.
  22. Here's A Tip, Folks by MightyMartian · · Score: 4, Informative

    Here's a tip, folks. The minute you see some science journalist use the word "paradigm", as in "paradigm shift" or "paradigm breaking" you can be quite certain that what follows will be neither.

    Horizontal gene transfer has been known about for decades, and the notion that the root of the tree of life is more a tangle of interconnecting branches has pretty much been accepted for some time now. We know that particularly with prokaryotes, horizontal transfer happens, and that while more difficult with eukaryotes, can still happen (ie. endo-retroviral insertions). It is yet another facet of evolution, not some independent force.

    --
    The world's burning. Moped Jesus spotted on I50. Details at 11.
    1. Re:Here's A Tip, Folks by Dalambertian · · Score: 5, Insightful
      Here's a protip I've learned from watching the internets and reading your first comment: The moment anyone brings to light something most people have been ignoring, there's always someone who comes along claiming that there's nothing new to see here and that anyone who doesn't know that is clearly misinformed. I'm sorry, but I've never heard of this theory before, and I daresay I'm not the only one. So, please, stop trying to take away my sense of wonder.

      Sincerely, the misinformed

    2. Re:Here's A Tip, Folks by icebike · · Score: 5, Informative

      Horizontal gene transfer has been known about for decades, and the notion that the root of the tree of life is more a tangle of interconnecting branches has pretty much been accepted for some time now.

      Further it has nothing at all to do with Darwinism.

      A mechanism of gene transfer plays no role in the "Survival of the Fittest" (a phrase coined not by Darwin, but rather by Spencer), or natural selection. Its not germane.

      Natural Selection is a winnowing process, and a mutation amplifying force, but says nothing about the acquisition or dispersion of said mutations. It was never meant to.

      --
      Sig Battery depleted. Reverting to safe mode.
    3. Re:Here's A Tip, Folks by MightyMartian · · Score: 4, Interesting

      I'm not trying to take away anyone's "sense of wonder". I'm saying that horizontal gene transfer is one known way in which variation can occur. Remember, evolution requires only that there be variation in populations. For the most part, that variation will either be in allele frequency, but sometimes is also mutational, sometimes due to neutral drift, and probably with considerably less frequency due to horizontal transfer. It ain't new, and neither is trying to make a well known phenomena sound exciting and "paradigm shifting" by announcing it to the world.

      Man, but I hate science journalism.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    4. Re:Here's A Tip, Folks by MightyMartian · · Score: 2, Interesting

      I think your confusing things here. Of course horizontal gene transfer can potential influence fitness. Evolution requires variability in traits. How exactly that variability gets there (mutation, mitosis, neutral drift, horizontal gene transfer) is the dirty details of evolution. However a trait makes it into a population, once its there, it can be fixed, and thus alter fitness.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    5. Re:Here's A Tip, Folks by icebike · · Score: 5, Informative

      I fail to see the point of confusion.

      Acquisition of a trait (by whatever means) would never amount to a significant percentage of the gene pool of an organism unless it proffered some usefulness. Mutation or horizontal genetic transfer are but mere mechanisms. Darwinism discusses the overall process, not the details.

      How that transfer took place is mere details. When that transfer takes place is not fixed in time. Horizontal transfer still exists in larger and more complex organisms and their symbiotic partners.

      --
      Sig Battery depleted. Reverting to safe mode.
    6. Re:Here's A Tip, Folks by Artifakt · · Score: 1

      Evolution requires that there be variation in individuals, and that there be selection.
      If the selection rate is such that species organize as fuzzy sets where most individuals are typical and only a few are seriously atypical, then there can be variations within (definable) populations. If the selection rate changes enough, just how fuzzy species membership is becomes an open topic - no one is really sure just how much individuals in a species could vary without the species becoming extinct.
      Mutation without selection is also possible - see stochastic mutation examples.
      If this theory is organizing a bunch of the alternative cases to the classic case of evolution modeled on whole species population changes, into a cohesive set of cases with common underlying properties, then yes, it's significant. Maybe not revolutionary, but pretty damned significant.

      --
      Who is John Cabal?
    7. Re:Here's A Tip, Folks by Jay+L · · Score: 1

      Man, but I hate science journalism.

      It. brought. us. here.

    8. Re:Here's A Tip, Folks by camperdave · · Score: 5, Insightful

      In other words, the tree of life is a banyan tree.

      --
      When our name is on the back of your car, we're behind you all the way!
    9. Re:Here's A Tip, Folks by gwern · · Score: 2, Funny

      > Evolution requires that there be variation in individuals, and that there be selection.

      That's odd. My vague memories of reading people like Dawkins keep whispering things like 'evolution is changes in allele frequency in a gene pool', which is obviously nonsense because that says nothing about 'individuals'.

    10. Re:Here's A Tip, Folks by Cassius+Corodes · · Score: 3, Insightful

      Depends who you mean - the article says most biologists didn't pay much attention to this and I think that is wrong. However to say most laymen did not know about this is probably correct. Also like GP I hate the phrase "paradigm shift" as I find its often brought up by purveyors of woo.

      --
      Control is an illusion, order our comforting lie. From chaos, through chaos, into chaos we fly
    11. Re:Here's A Tip, Folks by syousef · · Score: 3, Insightful

      Here's a tip, folks. The minute you see some science journalist use the word "paradigm", as in "paradigm shift" or "paradigm breaking" you can be quite certain that what follows will be neither.

      Thank goodness! Relativity and Quantum Mechanics make my head hurt. With this wonderful insight you've provided I can crawl back into my Newtonian clockwork universe shell and ignore them! ;-)

      More seriously. Pardigms do "shift" and get "broken". It's just that almost every journalist wants to sensationalise their news piece to sell it. That doesn't mean there aren't genuine breakthroughs. Just that you can't trust a journalist to tell you about them.

      --
      These posts express my own personal views, not those of my employer
    12. Re:Here's A Tip, Folks by Alphathon · · Score: 3, Informative

      First, if you wish to be taken seriously in an intellectual discussion, please learn the difference between your and you're. I am a grammar nazi (not that I'm proud of it - I can't help it and I blame my mum because she's even worse than I am :S) but things like that show a lack of thought behind posts.

      Anyway, back on topic. Icebike did not say that horizontal gene transfer cannot influence fitness, but that the mechnaism itself has no effect. What has the effect is the genes, not how they got there.

      Here's evolution by natural selection in a nut shell - organisms are different; some organisms are more suited to their environment than others; better ones survive and reproduce - their traits survive.

      Furthermore, Darwin had no knowledge of genes, as they were not known of in his day. This means that his theory does not even touch on the cause of the differences, but focuses on how they propogate. Thus Icebikes statement "Further it has nothing at all to do with Darwinism." because, as I said, Darwinism has nothing to do with genes.

      We now know how different traits come into being and what causes the changes (if not completelly then at least to a large degree - there's always more to be learned) so we can fill in the gaps, but that is evolutionary theory, not darwinism (the latter is a part of the former).

    13. Re:Here's A Tip, Folks by BrokenHalo · · Score: 5, Informative

      I'm sorry, but I've never heard of this theory before, and I daresay I'm not the only one.

      OK, here you go, then: Prokaryotes (i.e. bacteria, archea and so forth), by virtue of the comparatively "exposed" genetic material (not condensed or "bunched up" like ours typically is) and because of the structure of their cellular membranes, are very capable of "scraping up" any loose genetic material that may be lying around (e.g. as a result of cellular lysis). If these nucleic acids confer an evolutionary advantage, they are propagated in successive generations. This is why, and how "superbugs" like MRSA are thought to have evolved.

      Microbiologists have used this feature for decades in the genetic engineering of bacteria to induce desired characteristics. The process is much harder and more complicated in eukaryotic (e.g. animal or plant) cells, but it can and does happen.

    14. Re:Here's A Tip, Folks by svyyn · · Score: 1

      Evolution does not require selection. Genetic drift, purely stochastic changes in a population due to sampling when mating, is sufficient to cause changes in a population. More specifically, it is expected that 1/2N of the total mutations that arise in a population (where N is pop size) will randomly drift to fixation in a population. This means more mutations drift to fixation in smaller pops. It also means that reproductively isolated pops will drift apart, even if they have exactly equal selection.

    15. Re:Here's A Tip, Folks by BrokenHalo · · Score: 1

      It's just that almost every journalist wants to sensationalise their news piece to sell it.

      Indeed. Just as they always insist on using the term "Quantum Leap" to describe anything new or momentous, exposing their ignorance of the fact that a quantum leap happens over a very, very small distance.

    16. Re:Here's A Tip, Folks by svyyn · · Score: 3, Interesting

      Acquisition of a trait (by whatever means) would never amount to a significant percentage of the gene pool of an organism unless it proffered some usefulness.

      Though a popular view, that's not true. Assuming 'trait' means an independent mutation, then that trait can go to fixation in a population by simple chance (the expectation is that this happens to 1/2N mutations). Also, genes that are physically near each other on the genome tend to be passed as a set. Therefore, it is likely that a completely neutral, or even slightly disadvantageous mutation, that happens to be near an advantageous mutation (or a mutation that won the mating lottery and is heading toward fixation) will also be propagated throughout a population. There are other more esoteric reason why this could happen too, but a strictly adaptationist view of evolution was dropped in the 60s.

    17. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 1, Interesting

      Another way of thinking about horizontal gene transfer is that it's exactly like Darwinian evolution, but with the evolutionary units competing amongst themselves being the genes rather than the organisms. This is nothing new - this viewpoint was promulgated by Dawkins in "The Selfish Gene" back in the 70s.

    18. Re:Here's A Tip, Folks by ultranova · · Score: 1

      My vague memories of reading people like Dawkins keep whispering things like 'evolution is changes in allele frequency in a gene pool', which is obviously nonsense because that says nothing about 'individuals'.

      Dawkins himself came up with the concept of memetic evolution of culture, which doesn't involve such changes yet follows the same general idea.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    19. Re:Here's A Tip, Folks by khallow · · Score: 1

      Further it has nothing at all to do with Darwinism.

      This is wrong. Darwinism isn't natural selection. It's more than that:

      1) Traits are inherited.
      2) Traits affect the survivability of the organism.
      3) There is natural selection. That is, there's some process or events by which some organisms fail to reproduce.

      It's worth noting here that natural selection is only one point of three. The first point is the one that is changed by horizontal gene transfer. Darwinism assumes inheritance as the form of trait transfer. If you have other modes of transfer of traits (for example, Lamarckism), then the dynamics of biology can be substantially different than evolution. Another example is human learning. There's more information in a person's brain than in their DNA. The means by which a person learns is vastly different from evolution. While we learn a lot from our caregivers (who need not be related to us), we also can learn from anyone or anything we meet and observe. We also learn from activities.

      Hence, learning is not best described by evolution even though part can be modeled ok by evolutionary models (namely, the stuff kids learn from parents).

    20. Re:Here's A Tip, Folks by honkycat · · Score: 1

      That's a common mischaracterization of "quantum leap." Quantum only means that it is a discrete leap, not that it's a microscopic quantum. It's a quantum leap versus continuous drift. Not to say I don't think it's a hackneyed phrase, but that's not to do with its being inherently incorrect.

    21. Re:Here's A Tip, Folks by icebike · · Score: 3, Insightful

      1) Traits may be inherited. Clearly traits had to arise from somewhere, either mutations, the action of the environment physically changing an organism, acquired by horizontal gene transfer, or some as yet undiscovered method.

      Darwin never insisted that inheritance was the ONLY method of trait acquisition. Even he was was able to imagine backward a few million years and realize that the slight differences that were subsequently amplified had to have been acquired by some means he did not document. He often ruminated on this inability to quantify the source.

      This so called new theory does no violence to Darwin's basic premise.

       

      --
      Sig Battery depleted. Reverting to safe mode.
    22. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 0

      You both are right in this case. It was known for years on a non-scientific level. When I studied medicine almost twenty years ago, what is called horizontal evolution today was in the air but nobody I know did research on this. I am pretty happy to see thsi happen todayand that our non-scientific findings eventually get recognised. What happens now is giving this "knowlegde" a scientific basis. It's very important to have words so you can express your ideas.

      cb

    23. Re:Here's A Tip, Folks by Vintermann · · Score: 1

      Dawkins himself was for a very long time most ardent in rejecting endosymbiosis, arguably the first major instance of "non-darwinian" evolution that was found.

      --
      xkcd is not in the sudoers file. This incident will be reported.
    24. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 0

      If you want to restore some of your sense of wonder have a read of the following book:
            'Power, Sex, Suicide: Mitochondria and the Meaning of Life'
      It talks about one particular instance of horizontal evoluton that occured early in the evolution of life on earth, and the impact it had.

      The only slightly informed...

    25. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 1, Insightful

      It ain't new,

      It is to those of us who hadn't heard of it.

      and neither is trying to make a well known phenomena sound exciting and "paradigm shifting" by announcing it to the world.

      You don't have your paradigm shifted until you learn the new information. For most of us, that happens when it gets announced to the world.

      Man, but I hate science journalism.

      You are not the target audience.

    26. Re:Here's A Tip, Folks by Boronx · · Score: 1

      Inheritance is not trait acquisition at all in Darwin's theory, it's the method of successful trait propagation. If he'd assumed horizontal transfer of traits instead, he might have called his book "The Illusion of Species". All though if it were the dominant form of transfer for the sorts of critters he was talking about, I dare say there wouldn't be much of an illusion.

    27. Re:Here's A Tip, Folks by Avnerus · · Score: 1

      Have you read TFA? From what I understand, the breakthrough in this research is not the discovery of horizontal gene transfer in microbes, but of the fact it may have been, according to their simulations, the _primary_ factor in the evolution of the genetic code. That means that the idea of natural selection, in the development of the genetic code, is not the regular notion of survival of the fittest individual which passes its traits vertically, but rather the joined survival of a group of organisms based on their ability to share their genetic code horizontally.

    28. Re:Here's A Tip, Folks by chthon · · Score: 1

      I am busy reading The evolution of Species, and to be fair, Darwin himself seemed to recognise that the boundaries between species are very vague.

    29. Re:Here's A Tip, Folks by khallow · · Score: 1

      Point is, if there are other avenues for trait transfer, then you can end up with a situation where evolution is not the dominant means of organism change. For example, that could preclude the development of species even with evolutionary mechanisms in place. Evolution depends on trait transfer through inheritance dominating the process. Having said that, it appears to me that even in organisms with a great deal of horizontal transfer, there are distinct species. Perhaps the species have evolved to exploit horizontal transfer, but at the same time, there are significant portions of their genetic code which are immune to being replaced in horizontal transfer. Something like how contractors can come in to a company and do short term jobs, but they don't normally replace regular workers.

      I see this as a sort of market. There must be some mutual benefit to be gained and some penalty for not playing along (the Prisoner's Dilemma, where it is better for you to cheat on your associates than to cooperate). It's not clear to me what the carrots and sticks are for horizontal genetic transfer are. For example, suppose I'm a bad actor and send out genetic bits that would kill other bacteria that are my competitors? What are the disincentives to keep me from poisoning the well?

    30. Re:Here's A Tip, Folks by Kynde · · Score: 1

      Here's a protip I've learned from watching the internets and reading your first comment: The moment anyone brings to light something most people have been ignoring, there's always someone who comes along claiming that there's nothing new to see here and that anyone who doesn't know that is clearly misinformed. I'm sorry, but I've never heard of this theory before, and I daresay I'm not the only one. So, please, stop trying to take away my sense of wonder.

      Sincerely, the misinformed

      Granted, but the gp was only debunking the paradigm shift.

      And indeed, there _should_ be goddamn difference to "pradigm shifting work" and "here's something that will bewilder the lay-men but is already well known by scientists of the said field" in a science journalism!

      --
      1 Earth is warming, 2 It's us, 3 it's royally bad, 4 we need to take action NOW
    31. Re:Here's A Tip, Folks by Eclipse-now · · Score: 1

      I love science journalism because I'm not a scientist, and the science papers I've tried to read are more about impressing the potential buyers of the new product / impressing peers / getting college funding, etc, and so try to use plenty of 'big words'. Now I'm not completely unintelligent, but I'm from an Arts background. Thus Science Journalism is often the only way I get to know what these guys are talking about when they are not hiding behind the mystical veil of technospeak. So, I try to listen to Sciam podcast, The Science Show (Australian), Dr Karl (Australian) and Science Friday to keep up. Other than an enquiring mind, it's all I have.

    32. Re:Here's A Tip, Folks by ultranova · · Score: 3, Insightful

      Understandable, since Dawkins seems to view evolution almost religiously, so of course any deviation from dogma would be rejected as heresy.

      --

      Forget magic. Any technology distinguishable from divine power is insufficiently advanced.

    33. Re:Here's A Tip, Folks by Fred_A · · Score: 2, Interesting

      Man, but I hate science journalism.

      While I simply try to keep myself up to date and absolutely don't work in the field, I remember having read about this (namely eukaryotes grabbing strands from viruses) years ago. As I recall the title at the time was more along the line of "viruses sharing dna with organisms may open new research avenues" or something along those lines. Anyway it didn't strike me as being especially sensationalist. Since then I keep an eye open for further news upon those lines.

      OTOH, it seems that labs feel that they are in a race to be noticed so any time any of them has anything whatsoever that might be newsworthy, it always gets twisted into some kind of earth shattering event (and of course once one generalist publication starts doing it, others tend to follow). Of course most of the time nothing much comes out of it since that's the way research works (slowly). Apparently "The New Scientist" has some over-enthusiastic writers.

      --

      May contain traces of nut.
      Made from the freshest electrons.
    34. Re:Here's A Tip, Folks by nospam007 · · Score: 1

      "I'm saying that horizontal gene transfer is one known way in which variation can occur."

      And natural selection will still decide if it gets transmitted to the next generation.

    35. Re:Here's A Tip, Folks by Hal_Porter · · Score: 2, Informative

      Actually Francis Crick - who was a very strong atheist - used to like making pseudo religious phrases to torment the religious

      http://en.wikipedia.org/wiki/Central_dogma_of_molecular_biology#Use_of_the_term_.22dogma.22

      --
      echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
    36. Re:Here's A Tip, Folks by mcgrew · · Score: 1

      Man, but I hate science journalism.

      It appears to me that non-science journalism is little better. It's just that we nerds are more knowledgable about science than journalists are. I imagine a politician would say "man, but I hate political journalism."

      Journalists aren't about accuracy, truth, or enlightenment, they're about getting a paycheck from the parent corporation and maybe an award or two if they're lucky. They're only human, after all.

    37. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 0

      no, you're wrong. it's definitely jesus.

    38. Re:Here's A Tip, Folks by Anonymous Coward · · Score: 0

      Be careful there. It is quite feasible for a useless mutation to spread itself to a significant portion of the gene-pool, just by happening to occur in the same organism as a useful mutation, or even by sheer chance, happening to be in one of the relatively few members of a species to survive a major catastrophe by being in the right place at the right time.

    39. Re:Here's A Tip, Folks by mcgrew · · Score: 1

      Also like GP I hate the phrase "paradigm shift" as I find its often brought up by purveyors of woo.

      Glad to know that outlaw racing brings about a paradigm shift!

      (just joking, I know what you mean and agree with you.)

    40. Re:Here's A Tip, Folks by Danse · · Score: 1

      I love science journalism because I'm not a scientist, and the science papers I've tried to read are more about impressing the potential buyers of the new product / impressing peers / getting college funding, etc, and so try to use plenty of 'big words'.

      Not a very fair assumption about scientific papers. It's not that they're trying to impress, it's that they have to be precise in their wording and use "big words" that have very specific scientific meanings. That you don't know these words is understandable if you don't have any science background or education, but it's not a reason to attribute their usage to a desire to sound impressive or important. It's just the precise language of science. It's always disheartening to read this sort of thing from someone because it feeds into the current view of many in the U.S. of science as elitism. If science wasn't so valuable to industry, I shudder to think of what might be done to degrade it further in this country.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
    41. Re:Here's A Tip, Folks by omfglearntoplay · · Score: 1

      It all reminds me of Alien 4: resurrection, when Ripley's clones have her genes mixed with the alien genes. So if you could pick, what organism would you want to borrow some genes from? I'm thinking a dragon... half-dragon characters in DnD seem pretty well off. :)

    42. Re:Here's A Tip, Folks by BrokenHalo · · Score: 1

      You know what I meant. :-)

    43. Re:Here's A Tip, Folks by MightyMartian · · Score: 1

      And Kuhn himself admitted later that he had gone too far. As seriously as lots of laypeople with axes to grind against science admire Kuhn, most scientists pretty readily state they don't do science the way Kuhn said they did.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    44. Re:Here's A Tip, Folks by acheron12 · · Score: 1

      It was mentioned in Freeman Dyson's article Our Biotech Future, which is a good read in its own right if you haven't seen it already. (Yes, that Dyson.)

      --
      there is no god but truth, and reality is its prophet
    45. Re:Here's A Tip, Folks by Boronx · · Score: 1

      That's one his key points. Separation between species is a continuum and in some cases no division can be made, but in other cases, the division is quite clear. By the end of the book, species is a lot mushier concept than what people thought at the time, but still a useful one that reflects what's going on.

    46. Re:Here's A Tip, Folks by Hurricane78 · · Score: 1

      No. It’s a directed graph.

      It’s sad, how so many people oversimplified graphs. Into trees. Tables. and even lists.
      Think of class hierarchies in programming libraries. File systems with hard-coded roots and even the lack of links. Table-based databases. Mindmaps.
      Etc, etc, etc.
      It’s just way too simplified.

      But I’m working on a FS and UI element to fix this.

      --
      Any sufficiently advanced intelligence is indistinguishable from stupidity.
    47. Re:Here's A Tip, Folks by Vadim+Grinshpun · · Score: 1

      some organisms are more suited to their environment than others; better ones survive and reproduce - their traits survive.

      Just wanted to point out that the most important part is not so much survival as the ability to reproduce.
      A more accurate way to phrase this is that the "better" organisms get more opportunities to reproduce (e.g., by surviving longer, but perhaps for other reasons, such as being more attractive or more capable, etc.), and the "worse" ones get fewer opportunities to do so (for any of a multitude of reasons). All else being equal, over time, the "better" organism's offspring are going to outnumber those of the "worse" organism, eventually significantly so.

      I think this is a more enlightening description of natural selection, as it explains why it works a little better. I think I read this in one of Dawkins's books (either "Selfish Gene" or "Ancestor's Tale". Both are highly recommended, BTW; the latter isn't as well known, but is quite fascinating).

  23. Viruses by gedrin · · Score: 1

    It's interesting that infectious viruses may form an essential foundation for our own evolution. It may even be that viruses are a developed strategy for "importing tallent" from competitors or neighbors. It has interesting things to say about inerconnection between organisms in a species and between species. Infectability may be a long term strategy for development.

    Then again, it could be exactly the other way. Advanced organisms are just diverse platforms which viruses have evolved as elaborate tools and development shops for their survival and propagation.

    --
    Moderation : -1 Conservative Viewpoint
    1. Re:Viruses by BitZtream · · Score: 1

      'may' ?

      A bit of common sense, a little science and a history lesson makes it pretty clear that 'may play a part' really should be 'does play a part'

      EVERYTHING IS INTERCONNECTED. Nothing on Earth would have evolved over the same time period in the same pattern if you change any given part of it. The differences could be subtle enough that no one notices or so massive that an outside observer wouldn't ever think they started from the same point. The entire universe, while made of discrete components is all interconnected and everything down to the smallest level effects everything else in some way, even if its so minor we can't detect it.

      --
      Persistent Volume manager for Kubernetes - https://github.com/dwimsey/openshift-pvmanager
    2. Re:Viruses by bzdyelnik · · Score: 1

      and some of the best have been integrated into our genome http://en.wikipedia.org/wiki/Endogenous_retrovirus

    3. Re:Viruses by cyberfringe · · Score: 1
      ... and prions (infectious agents composed primarily of protein; responsible for a number of diseases in animals), what are also distributed laterally.

      Prions can confer evolutionary advantages through protein-based inheritance. http://www.ncbi.nlm.nih.gov/pubmed/11260797

      and are themselves subject to mutation and natural selection. http://www.ncbi.nlm.nih.gov/pubmed/20044542

      ...and parasites. Plant parasitism is a medium for horizontal gene transfer between different species Genes can be transmitted in both directions in this case. http://newsinfo.iu.edu/news/page/normal/1716.html

      --
      There's no sense in being precise when you don't even know what you're talking about. -- John von Neumann
  24. Viruses by Arancaytar · · Score: 4, Insightful

    Horizontal transfer isn't really over, either - we still have retroviruses.

  25. hopefully faggots are only a phase by Anonymous Coward · · Score: 0

    i hope they all die out forever

  26. Fascinating by koan · · Score: 1

    As to the vector for horizontal transmission of genetic material how about viruses?

    --
    "If any question why we died, Tell them because our fathers lied."
  27. Recent discoveries... by Uncle_Meataxe · · Score: 2, Informative

    There have been some other interesting discoveries regarding horizontal gene transfer recently. For example, this PNAS paper looks at sea slugs that can photosynthesize by themselves -- http://www.pnas.org/content/105/46/17867.full.pdf). The sea slugs photosynthesize through a combination of harvesting chloroplasts from the algae they eat and via horizontal transfer of genes involved in photosynthesis from these same algae. This is a bizarre and amazing discovery which demonstrates how genes can move from plants and be incorporated in an animal genome.

    1. Re:Recent discoveries... by tomatoguy · · Score: 1

      I laughed when I read about this - I thought "Gee, now that slug has to do even LESS to survive - what a slug!"

  28. Genetic Manipulation? by Anonymous Coward · · Score: 0

    yes, but not really surprising looking at jumping genes: http://en.wikipedia.org/wiki/Jumping_genes

    for me: GM might be more complicated than often thought....and maybe more dangerous.
    do we really know what we are doing?
    it seems there are more mechanism involved in genetics than: parent passes genes to offspring.

  29. Has anyone added this to a GA yet? by John+Hasler · · Score: 1

    n/t

    --
    Warning: this article may contain humor, sarcasm, parody, and perhaps even irony. Read at your own risk.
  30. GM Foods anyone? by Beerdood · · Score: 2, Insightful

    "horizontal gene transfer - in which organisms acquire genetic material "horizontally" from other organisms around them, rather than vertically from their parents or ancestors."

    Genetically modified foods are like the "artificial selection" equivalent of nature / natural selection - if the transfer of genes can happen from one set of species to another, then GM crops are kinds of an accelerated / selective version of this. If I were Monsanto or another big GM food company, I'd be looking to twist this into "Genetic material gets transferred to other species in nature, what's wrong with us doing it?"

    --
    Global warming and other natural disasters are a direct effect of the shrinking number of pirates - Gospel of the FSM
    1. Re:GM Foods anyone? by kanweg · · Score: 1

      A couple of answers to Monsanto
      - You're giving us only one or a couple of modified strains. Which means that if another pest develops, it puts the entire crops world wide in jeopardy
      - You pollute the genes to other plants.
      - You spread the genes and then sue a Canadian farmer for polluting his own stuff.

      Bert
      Who is a biochemist by original training, is a proponent of genetic engineering but only if you keep the organisms in tanks or if in big mammals including humans. A genetically engineered cow can be caught if it escaped. Men has a long history of fucking things up.

  31. I know by Anonymous Coward · · Score: 0

    I already beat it. The next phase has a really hard boss.

  32. We've heard this from our mothers for years... by Ransak · · Score: 1

    "You are what you eat."

    Cue the toilet humor in 3... 2... 1...

    --
    "Powers. I have them."
  33. Objectors vs. Occurs in nature by DragonWriter · · Score: 1

    As a side note... I wonder if the fact this occurs in nature will silence some of the people objecting to genetic splicing?

    Has the fact that miscarriage occurs in nature silenced the people objecting to induced abortion?

    Has the fact that death occurs in nature silenced the people objecting to murder?

    Has the fact that group conflicts over territory occur in nature silenced the people objecting to war?

    Has the fact that climate changes occur in nature silenced the people objecting to human actions which contribute to climate change?

    In general "X occurs in nature" does not silence people who object to humans choosing actions which use or result in X or something very much like it.

  34. Gene Synthesis by mosb1000 · · Score: 3, Interesting

    One of the big difficulties I have in understanding evolution is the process of gene syntheses. It seems reasonable that over time certain combinations of genes can win out over others, and certainly in bacteria you see this horizontal gene transfer happen all the time. You even see it in plants now thanks to genetic engineering, and before that you saw it in a more limited way thanks to viruses and cross-pollination and things like that. But all these things have to do with the transfer of genetic information between life-forms.

    The question in my mind is where did all the genes come from in the first place. Proteins are complex macro-molecules. It's not like one protein that catalyzes one reaction can simply mutate into a different protein that catalyzes a different reaction. It's more of an all or nothing thing. It doesn't seem like you would ever see transitional "evolutionary" forms of proteins for that reason. Worse still, you can't (as far as we know) start with a working a protein and reverse-transcribe from it into a strand of DNA or RNA that could code for it.

    What do you think?

    1. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      It doesn't need to be that complicated. Some simple forms of RNA are able to catalyze their own replication. Proteins, DNA, cells and organisms could be viewed as really hackish ways to facilitate replication of more complicated RNA forms.

      -M5B

    2. Re:Gene Synthesis by maxume · · Score: 1

      I think you are overestimating your ability to cope with several billion years.

      (I'm not insisting that I am any better at it, but I am willing to believe that lots of things can happen in 1 billion years, no matter how improbable)

      --
      Nerd rage is the funniest rage.
    3. Re:Gene Synthesis by SpinyNorman · · Score: 2

      DNA is what evolves - i.e. instructions to make proteins, not proteins themselves. Of course most random changes to the instructions are maladaptive or at best useless, but very occasionally not.

      I think what happens in practice is that it's the "useless" changes (do no harm, but under current conditions do no good) that may play the largest role... these can accumulate in different populations of a species and become a differentiator when the environment changes (which is the real driver of evolution) and previously useless traits become either helpful or harmful.

    4. Re:Gene Synthesis by brit74 · · Score: 4, Interesting

      It's not like one protein that catalyzes one reaction can simply mutate into a different protein that catalyzes a different reaction. It's more of an all or nothing thing. It doesn't seem like you would ever see transitional "evolutionary" forms of proteins for that reason.

      There are instances of proteins evolving into something that does something different.

      "Biologists have shown that independent but similar molecular changes turned a harmless digestive enzyme into a toxin in two unrelated species -- a shrew and a lizard -- giving each a venomous bite."
      http://www.sciencedaily.com/releases/2009/10/091029125532.htm

      Generally, what happens in these cases (where a protein evolved into a different protein with a different function) is that the original DNA sequence gets duplicated, and then one of the duplicates starts evolving (and the other copy continues to serve the same original function that it had earlier). One of the things that evolutionary biologists do is look at protein sequences and find similar sequences within the same organism. Very often, there's a tree-like structure showing multiple variations on a single protein within an organism. For example, humans have multiple copies/variations on the hemoglobin gene. They're either inactive or active at different phases in a person's life. Example:

      "Fetal hemoglobin, or foetal haemoglobin, (also hemoglobin F or HbF) is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old. Functionally, fetal hemoglobin differs most from adult hemoglobin in that it is able to bind oxygen with greater affinity than the adult form, giving the developing fetus better access to oxygen from the mother's bloodstream."
      http://en.wikipedia.org/wiki/Hemoglobin_F
      http://en.wikipedia.org/wiki/Hemoglobin#Types_in_humans

      There's also the case of the fish antifreeze that evolved from non-protein-coding DNA:
      "Scientists at the University of Illinois have discovered an antifreeze-protein gene in cod that has evolved from non-coding or 'junk' DNA."
      http://www.sciencedaily.com/releases/2006/04/060404090831.htm

    5. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      This is one of the key issues with the origin of life. Basic life processes are made up of so many inter-connected and inter-regulating components that it creates a catch-22 in figuring out which cam first.

      If I recall though, many of life's building blocks have been observed in self-replication. I do believe ssRNA had been observed self-annealed and self-propagating/self-elongating. Not sure about proteins.

      One major important factor to consider is that life had all the time it needed to form, it didn't have a deadline. So if one kind of component wasn't ready, the others could just exist (dynamically) for a while until it was ready. Proto-life may have been very incomplete, and the first "cell(s)" may have "lived" for a very long time until they became able to perform metabolically at a reasonable rate, reproduce, etc.

      I don't know if we'll ever be able to know what proto-life was like on Earth (assuming life originated on this planet and didn't arrive), as all the innovations of the genetic and metabolic machinery would obsolete any "lifeforms" that would just 'leave it to chance' for things to react.

      It would be amazing if we found life on other celestial bodies, but it would be equally to find proto-life, assuming we could distinguish it from a pile of carbon goo.

    6. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      There is a big gap between the so called primordial world or RNA world and the first forms of unicellular organisms, the ones holding a specialized set of genes, the genome. For such a gap there is little known. So it is very hard to know from where all these genes came in the first place. However, geneticists from the early 50's started to describe many different mechanisms by which a gene can duplicate, get transferred or gain a new function. In some cases such a function allowed the organism to live in an otherwise killer environment. Later in 60's along with the development of DNA/RNA sequencing techniques, many other genes and their phenotypes were characterized giving a light to a bunch of more sophisticated mechanism of function gain. For example and related to article in discussion, horizontal gene transfer, gene duplication, gene regulation, de-regulation, partial gene transfer, etc. Now we are in the genomic era, where an entire genome can be sequenced with a bunch of bucks. So there is a sea of data showing impressive things on how genomes can earn players. For example and answering your question, yes an enzyme can gain a function by changing very little of the total protein (less than 5%). Or membrane proteins, they can share up to 98% identity on their structure but yet bind different targets. And yes, there are enzymes that are specialized for one substrate but also very related ones can take more substrates. A lot has been done in this field as well, where by single aminoacid substitutions a different substrate was selected. So it is not an all or nothing thing. Specially if considering that genes code for proteins, but that this proteins are composed of domains. For example, the insertion of a domain into a protein would change its subcellular target, and therefore maybe its function.

      So there are enough mechanisms to explain how unicellular organisms of about 2.8K genes got 30K more genes to become humans. However, what is remarkable is that an insignificant microbe has only 10 times less genes that us....

    7. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      Whilst Proteins have catalytic properties but aren't good for transferring information and DNA is good at storing information but doesn't act as a catalyst RNA can do both. RNA transfers genetic info from DNA out of the nucleus where other RNA structures called ribosomes can translate the code into proteins... But one hypothesis is that RNA could thus form self-replicating strands, some of which adapted over time to polymerise DNA and proteins from their building blocks.

    8. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      Occasionally, large portions of DNA are copied, potentially resulting in two copies of a gene. This leaves the gene free to evolve without needing to maintain its critical functionality, since the other copy can do so. Hence, you get a fully functional new gene, though at the start its function is identical to that of another. But having the backup copy means that it can evolve to take a different role, whether slightly different or very different.

    9. Re:Gene Synthesis by presidenteloco · · Score: 1

      First, take all the alternative molecules that can be formed by a given RNA-like molecule (call that molecular structure b, for reasons
      that may shortly become obvious) with only one or very few
      point mutations or section permutations. If we make the (rather strong) analogy of the RNA-like molecule
      to a particular construction-program-representing bitstring value, then we are considering the set of alternative bitstring values
      which have low relative Kolmogorov complexity compared to the original bitstring value.
      Consider the set of molecules(bitstrings) which can be produced by only a few simple and probable/feasible-by-chance-or-thermodynamics
      physical process steps, (i.e. by a few local program steps), given the original molecule(bitstring) as a starting point.
      Call that set of molecules/bitstrings Sb.

      Now consider the subset of Sb, S'b which codes for structures/processes which, in the context of the surrounding structures/processes
      that Sb codes for, and additionally in the context of the prevailing set of probable environmental states C, will do no harm to the continuation
      of the whole homeostatic and replicating structure/process.

      Now consider the subset of S'b, S''b, which codes for structures/processes that have an adaptive (survival probability) advantage in
      the prevailing environment C.

      Evolution of any currently extant (ergo successful) structure-construction program-encoding molecule b will tend to
      proceed at each step from b to a b'' which is found in S''b.

      A more complex picture would see a mix of moves from b to b' (in S'b) (harmless,useless mutations) as well as moves straight
      from b, or through any b', to b'' or to b''', but roughly, the end-effect is moves from b to a b'', repeat ad nauseum.

      There are two constraints operating here. The first is that the program code evolution must be probable and feasible.
      The second is that the work-product variation caused by the program code variation must be at least
      non-destructive (so it can hang around as fodder for usefulness should the environment C change), or must be
      adaptive i.e. MTBF(b'',C) > MTBF(b,C), where F, failure, is defined as loss of any existence/embodiment of the molecular
      structure/bitstring b in that (causally connected) spacetime region.

      That is, pseudo-mathematically speaking, the direction that evolution will tend to take.

      But it leaves the question of how simple the simplest reliably surviving b + b-replicating context/machine
      (i.e. the simplest self-creating Turing machine) was, and what it would have been like, chemically, and how that
      worked, exactly.

      --

      Where are we going and why are we in a handbasket?
    10. Re:Gene Synthesis by Anonymous Coward · · Score: 0

      New proteins usually emerge through mutations in gene sequences that are already present. If you want to get a new protein and still retain the old protein from which it is derived, the
      gene has to be duplicated first, after which mutations can change the function of one (or both...) of the two copies. Gene duplication happens regularly "by chance" and would usually be
      considered DNA damage, but in fact pretty much all proteins start out like that: As identical copies of previously existing proteins. Since there are then two copies of the gene in the genome, one
      of the copies has become redundant and can accumulate mutations as long as they have a neutral effect on overall fitness. This might lead to functional changes over time, some of which can be beneficial. It's not true that you will not find "intermediate" forms of proteins in nature, if you look at the same gene in different species (that is, a gene that has a common ancestor), all of them will
      be slightly different. There have been studies done in microbes to try to understand exactly how these very slight differences modify the function of the protein and by extension the fitness of the organism. You need to keep in mind that there are a lot of mutations that you can introduce in a functional protein that will not make the protein unfunctional, but just slightly less or slightly more functional, or change it's function slightly. In that way, a complicated organism such as a eukaryote already has a gigantic amount of functional genes that can be used as scaffolds to build new genes. If you start comparing proteins in an organism, you will find that certain parts of their sequences come up again and again, these are called protein domains. These are like functional building block to a degree, and can be reused after gene duplication.

  35. pathogens by Taibhsear · · Score: 1

    Horizontal gene passing is what make several organisms have strains that go from harmless to pathogenic.
    Some useful info for the curious masses:
    http://en.wikipedia.org/wiki/Pilus
    http://en.wikipedia.org/wiki/Horizontal_gene_transfer

  36. Let me explain... by denzacar · · Score: 3, Insightful

    Just why is it that ultra-conservative rants about God or racial superiority or anti-socialism are instantly modded off-topic, troll, and/or flamebait until they sink beneath the thresh hold and yet completely off-topic attacks on Creationism in every story even vaguely connected with biology or evolution get modded +5 insightful?

    Same reason why at least someone will look favorably on the fact that you may have served pizza for desert, while you will be forever banished from the kitchen (and other places) if you serve up a pile of dung.

    Both are off-topic, but while one still satisfies the basic requirements - the other is a pile of shit.

    In the case of pizza - it is still food; in case of pointing out the errors of creationism - it is still a discussion about evolutionary theories, it only digresses towards pointing out the wrong ones.
    Creationism and a plate full of dung - a pile of shit.

    --
    Mit der Dummheit kämpfen Götter selbst vergebens
    1. Re:Let me explain... by RobinEggs · · Score: 1

      ...[criticizing creationism] is still a discussion about evolutionary theories, it only digresses towards pointing out the wrong ones.

      Except that it's not a mere digression when it's so many respondents first (and only) thing to contribute; it's just hate and smug dismissal of someone not even in the conversation masquerading as a contribution.

    2. Re:Let me explain... by denzacar · · Score: 1

      Some people involved in the conversation that are actually considering evolution theory might still find it sensible. (I.e. Some people are human males, some human female.)

      On the other hand, utter nonsense is and will be utter nonsense to willing to actually consider evolution theory. (I.e. All human males are people.)

      --
      Mit der Dummheit kämpfen Götter selbst vergebens
    3. Re:Let me explain... by Danse · · Score: 1

      ...[criticizing creationism] is still a discussion about evolutionary theories, it only digresses towards pointing out the wrong ones.

      Except that it's not a mere digression when it's so many respondents first (and only) thing to contribute; it's just hate and smug dismissal of someone not even in the conversation masquerading as a contribution.

      Smug dismissal, sure. Hate? I don't think so. Do I hate the guy doing something dumb in a YouTube video? No, but I may ridicule him and laugh at him. Hate is reserved for those who lie and try to do things like getting I.D. taught in schools or pass laws to impose their religious beliefs on others.

      --
      It's not enough to bash in heads, you've got to bash in minds. - Captain Hammer
  37. Explains a lot by joepress99 · · Score: 1

    especially my co-workers

  38. darwin didn't know the details? shocking! by panthroman · · Score: 4, Insightful

    Have Woese and Goldenfeld a brilliant new idea? All they're saying, I think, is that "parent" and "child" are the appropriate units of selection only when genes are passed vertically: from parent to child. They're suggesting that horizontal gene transfer is underrated as a historical evolutionary force.

    Agree or not, it hardly undermines Darwin. Genes weren't known in the 19th century. Darwin didn't have a clue about genes, so we're gonna knock him for being "wrong" about it? I mean, was Jesus wrong about genes, too? It's anachronistic silliness.

    Science is fundamentally dynamic. Any science that hasn't progressed in 150 years ain't doing too well. (Dear creationists: stop calling us "Darwinists." We've moved on.) I mean, The Origin came out in 1859, for crying out loud! Darwin was more brilliant, more insightful, and rightly more famous than I'll ever be. But if we both had to take a biology test right now, I'd kill him.

  39. Hey wait, does this mean... by Redon · · Score: 1

    ...early life was open-source?! :D

    1. Re:Hey wait, does this mean... by Redon · · Score: 1

      From the article: "It would have acted as an innovation-sharing protocol," says Goldenfeld, "greatly enhancing the ability of organisms to share genetic innovations that were beneficial."

  40. That's very true by aflag · · Score: 1

    it's how peter parker got his powers!

  41. Recent evidence for horizontal gene transfer by ther.geek · · Score: 1

    Spider-man and Batman are the proof of horizontal gene transfer theory.

  42. Darwinian Evolution Considered As a Phase by Phizzle · · Score: 1

    between Creationism and Global Warming!!! OMGZ

    --
    I will not be pushed, filed, stamped, indexed, briefed, debriefed or numbered. My life is my own.
  43. Outstanding point by sgt_doom · · Score: 1

    Outstanding concept - and correct, of course!

    Of course, it is great research, but also quite obvious to the rest of us as viral transfer of DNA material has been known for quite some time, and numerous research grants were submitted in the late '70s and early '80s --- unfortunately that was the time of the anti-science of Reagan and the first wave of neocons.

  44. Almost no trash-talking - nice by tbird20d · · Score: 1

    It was refreshing to read the article and comments without the usual trash-talking between creationists and non-creationists. Maybe the moderators are doing a good job and the trash-talking is just below my threshold, but it's really nice. If civility has broken out on Slashdot, thanks everyone!

  45. Isn't horizontal gene transfer just ... by newhoggy · · Score: 1

    an example of Darwinian Evolution, but just at a different level?

    For example, if you think of the unit of evolution as a gene instead of an organism and a bacteria as a habitat instead of an organism, then the gene evolves vertically, by replication and duplication. The transfer between two bacteria are just the gene migrating from one habitat to another.

  46. RTFA by gpronger · · Score: 1

    A key point of the article that seems to have slipped past a fair number here is that the researchers are attempting to explain the robustness of the gene replication:

    "Evidence for this lies in the genetic code, say Woese and Goldenfeld. Though it was discovered in the 1960s, no one had been able to explain how evolution could have made it so exquisitely tuned to resisting errors. Mutations happen in DNA coding all the time, and yet the proteins it produces often remain unaffected by these glitches. Darwinian evolution simply cannot explain how such a code could arise. But horizontal gene transfer can, say Woese and Goldenfeld."

    And:

    "In 1991, geneticists David Haig and Lawrence Hurst at the University of Oxford went further, showing that the code's level of error tolerance is truly remarkable. They studied the error tolerance of an enormous number of hypothetical genetic codes, all built from the same base pairs but with codons associated randomly with amino acids. They found that the actual code is around one in a million in terms of how good it is at error mitigation. "The actual genetic code," says Goldenfeld, "stands out like a sore thumb as being the best possible." That would seem to demand some evolutionary explanation. Yet, until now, no one has found one. The reason, say Woese and Goldenfeld, is that everyone has been thinking in terms of the wrong kind of evolution."

    The point is that vertical evolution cant' get all the branches to the same point in the stability of gene coding. Their argument is that the fundamental mechanism that allows the system to move forward needed to evolve via vertical transfer and not horizontal.

    It's true that its been known for a while, but the significance of horizontal transfer has not.

  47. I can hear them now.... by elitest · · Score: 0

    I'm sure when the creationists hear "Parallel Evolution" they think "God did it"

  48. Like mullets and backtalk... by PinchDuck · · Score: 1

    You'll grow out of it.

  49. The funny thing is by WindBourne · · Score: 1

    That I have been saying that here for the last 8 years. And this was talked at in the CDC lab that I worked at back in 1981. IOW, this is not a new theory. All you have to do is pay attention to how things are jumping. It has everything to do with bio density of population and how fast virus mutates. It also has to do with the blood transfusions in which we transfer these virus.

    My guess is that a number of asymptomatic virus exists that are slowly able to move from species to species. Those will increase our evolution. Oddly, it means that it will allow us to pick up diseases that take decades to show. My guess is that when we have a colony on Mars, we will get to see evolution difference show up.

    --
    I prefer the "u" in honour as it seems to be missing these days.
  50. Dubious by Thuktun · · Score: 1

    Natural selection describes a process by which beneficial mutations are kept and improve the suitability of a species to its environs. It does not talk about genetics at all. Why wouldn't mutations caused by horizontal gene transfer also apply to natural selection?

  51. They are the same in the beginning by copponex · · Score: 2, Insightful

    You're right - religion and science are the same in one sense. They are guesses at what reality is.

    The largest difference is that science acknowledges that it is a guess. A very educated guess, which yes yielded modern life as we know it. Religion tries to claim that it is the truth, and the only truth, and expects it's adherents to doggedly follow it's rules and values way beyond their useful context. To give you an example, a slashdot poster recently gave a ridiculously long opinion on whether pig meat cultivated in a lab would be kosher or not.

    Now, religion in it's early days claimed to heal the sick, to make the blind see, and to allow the lame to walk again. It has never done any of these things. Science, on the other hand, has done all of these things and much more. I'll stick with the continued results of the scientific method. You can keep your bronze age mysticism.

    1. Re:They are the same in the beginning by copponex · · Score: 1

      The second sentence of the second paragraph should read, "A very educated guess, which has yielded modern life as we know it."

      Science has not yielded a better in-browser grammar check - yet.

    2. Re:They are the same in the beginning by repapetilto · · Score: 1

      grammar is passe. Its pointless to understand it beyond what you need to know to get your own ideas understood... and that requirement changes all the time.

  52. Spider-Man, yes, Batman no by DoctorFrog · · Score: 1

    GO back to the comic book store and do your research properly, or I'll make you hammer your hamster.

  53. Jumpin' Genes, Grandma! by thomst · · Score: 1

    Does this remind anyone else of Greg Bear's Darwin's Radio/Darwin's Children duology? 'Cause it sure reminds me of them!

    --
    Check out my novel.
  54. I don't know about horizontal evolution but... by lindseyp · · Score: 1

    it was certainly horizontal gymnastics that led to my kid's genetic code being built.

    --
    j'ai découvert une démonstration vraiment admirable (de ce théorème général) que cette si
  55. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  56. Swamp Thing. by Somecallmechief · · Score: 1

    His genetic heritage "selected" him for survival. As millions of scientists simultaneously exposed themselves to vast arrays of chemicals in lab environments (with either no regard for common knowledge safety recommendations or that basic distrust of other scientists exhibiting the occasional evil laugh) and produced offspring; it was a matter of when, not if, Alex would be born. Naturally selected to survive both explosion and immersion in a primordial stew of chemicals, he then received the genetic code of the swamp "horizontally", as it were, thus simultaneously being the fittest and taking the fittest. I think Swamp Thing has a lesson for us all.

    --
    If it looks like a duck, let's call it a moose.
  57. Human Interaction by smd75 · · Score: 1

    I would believe that it could be considered a phase now, because due to human interaction, we've slowed its effectiveness. german engineered cars, selective breeding of animals and plants, Engineering crops to survive in locales that don't support that type of life, Geoengineering to farm in the desert (which I find funny when people complain about a drought IN THE DESERT)

    Humans have taken the darwinism theory and shot it to hell.
    Yes, at one time, it was a trend, now it has passed.

    --
    Im a troll because I disagree with you.
  58. Re:darwin didn't know the details? shocking! by Artifakt · · Score: 1

    It's not that this 'undermines' Darwin, or that Darwin was 'wrong' about genes, but Evolutionary theory is a hybred. It combines Darwin's insight that natural pressures can select a subset of each generation to differentially reproduce, and Mendel's genetics. When Darwin proposed Natural Selection, he made predictions, such as that whatever mechanisms Heredity used, those mechanisms could not allow for unlimited blending of traits. Mendel's experiments showed how there could be non-blendable control mechanisms at the heart of the reproductive process. It's not just that mutation is a requirement along side natural selection to have the whole theory of Evolution, but that one of Darwin's conditions is the code being occasionally mutated must be a code that doesn't allow more than, at most, very limited blending. So, a non-Mendelian form of genetic transfer doesn't necessarily support Darwin's idea of how selection can work to produce long term changes, and if it doesn't, you can't (or shouldn't) call what's happening in such cases 'evolution'.

    --
    Who is John Cabal?
  59. Asari? by Vastad · · Score: 1

    Did anyone else read the summary and suddenly think some scientist has gone an actually elevated the status of the Asari in Mass Effect from a horndog trope to sledgehammer blue alien lesbians into hard sci-fi...into the realm of 'egads!-it-could-happen?-ism'....???

    1. Re:Asari? by Anonymous Coward · · Score: 0

      Did anyone else read the summary and suddenly think some scientist has gone an actually elevated the status of the Asari in Mass Effect from a horndog trope to sledgehammer blue alien lesbians into hard sci-fi...into the realm of 'egads!-it-could-happen?-ism'....???

      You didn't need Mass Effect to posit this as scientifically possible, it has already happened to very common species on Earth, just not to vertebrate species. I'm surprised that an author hard science fiction author hasn't written a serious story about a similar scenario happening to an intelligent species (or if someone has I haven't encounter any works).

  60. Earth is an organism by Anonymous Coward · · Score: 0

    Its better to consider all life on Earth as part of a single organism. Makes one wonder what happens with the decimation of biodiversity.

  61. I have a theory by JimboFBX · · Score: 1

    I have a theory that "genetic momentum", for lack of a better term, exists. Its where you have genes that dictate what your children will have, sort of like code that writes its own code. This kind of phenomena would allow for, for example, giraffes to evolve fairly quickly because there would be a gene that gives their children a longer neck than themselves. This could be the function of what is known as "junk" DNA. Of course, I would like to know if anyone else has heard of something like this, and if it has been proven to exist or not.

  62. Evolution cannot explain error-resistant DNA by davide+marney · · Score: 1

    From the article:

    Though [the genetic code] was discovered in the 1960s, no one had been able to explain how evolution could have made it so exquisitely tuned to resisting errors. Mutations happen in DNA coding all the time, and yet the proteins it produces often remain unaffected by these glitches. Darwinian evolution simply cannot explain how such a code could arise. But horizontal gene transfer can, say Woese and Goldenfeld.

    Interesting.

    --
    "We receive as friendly that which agrees with, we resist with dislike that which opposes us" - Faraday
    1. Re:Evolution cannot explain error-resistant DNA by pydev · · Score: 1

      Yeah, but bullshit. Replication and transcription errors follow pretty straightforward laws.

    2. Re:Evolution cannot explain error-resistant DNA by davide+marney · · Score: 1

      I believe the authors' point is that even though the errors do get replicated as you say, the resulting proteins created by the code are often unaffected by them. It's the resistance to error that's hard for Darwinian evolution to explain.

      --
      "We receive as friendly that which agrees with, we resist with dislike that which opposes us" - Faraday
    3. Re:Evolution cannot explain error-resistant DNA by pydev · · Score: 1

      Making bad proteins wastes energy and may even kill the cell, so there's selective pressure against making them.

      Also, even more simply, the genetic code has some redundancy built in, so some mutations don't change the protein. In addition, mutations in introns don't change the protein.

      I really don't see anything unexpected there.

  63. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion

  64. This is significant by Chicken_Kickers · · Score: 1

    Someone above ranted about the overuse of the word "paradigm-shift" and I couldn't agree more. However, in this case, I think the use is warranted. Woese himself caused a paradigm-shift when he discovered that the 16S and 18S ribosomal gene is highly conserved in all known organism, meaning that organisms that have similar 16S or 18S sequences are more closely related to each other and vice versa. The previous paradigm, and if you were old enough to remember learning in school was based largely on the morphological and to a certain extent, biochemical properties of the organisms. The current model used in life-sciences are tree-like where "more evolved" species branch off from "less evolved" species and if you trace back this tree, you get to the root of life, where the hypothetical Last Universal Common Ancestor (LUCA)is. This new paradigm proposed by Woese drastically change this neat picture into a cloud-like diagram, with organisms having multiple links with other organisms. No longer can you say organism x2 has a direct lineage to organism x1 since horizontal gene transfers have clouded the relationships with a big impact on the study of evolution. This also has a big impact on computational biology and I am sure, this is more in line with the speciality of the Slashdot crowd. More complex algorithms and computational power have to be utilised to visualize this 3D relationship. As an aside, to those who are virulently defending Darwin, please stop and reconsider what you are doing. I'm not saying that you shouldn't but amidst calls to boycott the New Scientist by Dawkins himself, don't fall into the same behaviour that you tarred the intelligent design crowd.

  65. Old Hat by Sam+Garedner · · Score: 1

    In my classes genetics I learned this some 30 years ago, so why an article now?

  66. gene modification is not evolution by Nowhere.Men · · Score: 1

    How the individuals changes ( horizontal or vertical gene modification, OGM) is separate from the selection effects that drives evolution.

    In his lab, a scientist may come up with lot of gene modification but only the one he will be able to sell (one selection effect, Darwin may not have though about)) will go into the fields where they can breed with the wild flora.

  67. Viruses write their DNA into ours so ... by nilbog · · Score: 1

    So I get genital herpes and it writes itself into my DNA. Is this horizontal gene transfer because I did not get that genetic code from a parent? More importantly, how can these be genital herpes if they're on my face?

    --
    or else!
    1. Re:Viruses write their DNA into ours so ... by lee1 · · Score: 1

      So I get genital herpes and it writes itself into my DNA. Is this horizontal gene transfer because I did not get that genetic code from a parent?

      One can only hope.

  68. Oblig. by Tibia1 · · Score: 1

    Monkey see monkey do? I'd imagine someone has already written this.
    Individuals learn from surrounding individuals. If you observe a baby you can understand this, as I'm sure pre-language humans did.

  69. Darwin did not get everything correct by Anonymous Coward · · Score: 0

    I don't recall much about "horizontal" evolution in "On the Oriigin of Species ...". He did recognize a lot of natural hybridization in the plant world. Darwin did pretty well with what was known 150 years ago.. DNA structure has only been known for 50-60 years? . He also seemed to focus heavily on facing entrenched dogma of his day and still faces today.

    Enzymes do more than one job and sometimes can quickly take on new rolls. Prions certainly give credence to that. I don't see where it conflicts with Darwin, other than it blurs the distinction between what is living and what is not.. We also see evidence of enzyme with a common heritage. This is pretty much anticipated by Darwin without locking down the the mechanics of genetics.

    We are still learning about how DNA works. Sometimes inheritance is not just which chromosome you get. It can depend on methylization of that chromosome. Which can lead to a sort inheritance of acquired traits. Not exactly keeping with Darwin's notions. Also DNA encodes vital information in a sophisticated choreography of coils, kinks, loops and packing of a meter of DNA in cubic micron that is some how passed from generation to generation. We see gene interaction that we would not expect from genes that are so distant on a chromosome.

    We still have much to learn about DNA. Darwin's notion of variation in a population does mesh well with DNA replication that makes inexact copies and even Lendl's experiments. The inexact copying that occurs maybe enhanced and suppressed in countless ways. There are single nucleotide substitutions, transposons, deletions, swaps, telomeres, splits and joins. And then we can have extra copies of a chromosomes or even extra sets of chromosomes. Today we have debates about the notion of a molecular clock.

    Darwin was rather tied tied the notion of species. It works in many situations and is a great reference point when life takes a different turn. Life has a way of doing just about anything. In the microbial world species is a loaded term. "Horizontal" evolution may not strictly alter the topology of the Darwin's tree of life. It leads to quite a tangle in the roots and a chance to reexamine it.. The transition to the bonzai banyan model vs from the oak model is a powerful paradigm shift. It is important in the microbial world. With our own bodies cells outnumbered 10:1 by microbes and reproduction rates that outpace ours by several orders of magnitude we will see and do see the power of horizontal evolution. We are in a struggle with life on Earth. Humanity really has two checks on its population we have each other and we have microbes. The microbes are doing most of the work. They would have succeeded long ago or stopped it from ever happening if it weren't for the passification, collaboration and domestication of some useful allies in the microbe world by us and our ancestors. As we strain the capacity of Earth they we will provide them with new opportunities for dealing with humanity.

  70. horizontal evolution in humans? implications? by Anonymous Coward · · Score: 0

    A mother carries parts of the genome of her offspring in her blood. If the genes get into effect the father of this child injected part of his genome into the mother and changed her biological identity.

    What about rape? What's the impact on personal integrity?

    cb

  71. Evolution of Replicators by secondhand_Buddah · · Score: 1

    I don't necessarily agree with the conclusions presented here. Susan Blackmore and Richard Dawkins have described evolution differently -
    http://www.ted.com/talks/susan_blackmore_on_memes_and_temes.html . The idea relates to replicators, and that the replicators actually evolve, and that genetic replicators are only one form of replication. Wherever there is replication, there is evolution. This relates to genes, and the category described by Dawkins, memes. Susan Blackmore identified a new replicator named temes. (described in the linked video). In this paradigm, evolution relates to replicators adapting to new environments to survive, which could easily apply to organisms that do not partake in genetic evolution.

    --
    Participatory Governance : The only feasible option for a real democracy, where everyone really does have a say.
  72. nothing mind-bending about it by pydev · · Score: 1

    Horizontal gene transfer has been known for a long time, as has its influence on bacterial evolution. So, there is really little fundamentally new insight in this paper.

  73. *cough* by The+Creator · · Score: 1

    1. An information storage medium.

    2. A mechanism for reproducing that information such that certain pieces of information are more likely to get reproduced than others.

    3. Mutation.

    And 2 needs to be further qualified so the the probability of reproduction hinges on some critia.

    --

    FRA: STFU GTFO
  74. What we need is a paradigm shift. by MrMr · · Score: 1

    Away from paradigms and towards an evolutionary theory of the development of science.
    Btw, Horizontal gene transfer is only different from 'standard' evolution if you think all evolution occurs at the organism level instead of at the gene level.
    I could recommend an excellent book on that subject.

  75. One of the most interesting things I've read by Asterra · · Score: 0

    One of the most interesting things I've read in a while.

    Like Carl Sagan said, science is self-correcting. He also said you have to back up big statements with big evidence. So best of luck to this theory, in that respect.

  76. Darwin didn;t even know DNA existed. by Anonymous Coward · · Score: 1, Insightful

    Darwin didn;t even know DNA existed. So genes were unknown. But still he came up with his theory of evolution. This *ought* to show people that *how* DNA manages to make mutations wasn't part of the theory.

    But it seems like they think that DNA making mutations differently shakes the theory.

  77. Attacking Darwin sells issues by VShael · · Score: 2, Insightful

    It seems to me that one of the reasons journalism science is so bad, is that they believe (rightly or wrongly) that any article which appears to be saying "DARWIN WAS WRONG!" will sell more copies.

    The article doesn't say that, obviously, but it at a cursory glance it could be perceived as that.

  78. And the frothing proGM fanatic... by Anonymous Coward · · Score: 0

    And the frothing proGM fanatic keeps proposing the myth that GM foods are there to help the world feed itself.

    They say there's nothing that could go wrong with adding genes inside other genes and bypassing 1000000 generations of transfer and testing against the world environment.

    And they make up what the antiGM famatic says (seriously: I've NEVER heard anyone explain that frankenfoods must arise because you can stick random genes in an organism and it will survive. NEVER).

  79. Horizontal gene transfer less selective by Anonymous Coward · · Score: 0

    If you want to explain adaption and the rich variety in nature then a more selective process like vertical gene transfer are probably more relevant.

    I think its a question of relevance rather than ignorance from the evolutionary biologists part.

  80. Re:darwin didn't know the details? shocking! by Kynde · · Score: 1

    I mean, was Jesus wrong about genes, too?

    Well, I don't know quite how to put it, but yes.

    --
    1 Earth is warming, 2 It's us, 3 it's royally bad, 4 we need to take action NOW
  81. Really? by harrytuttle777 · · Score: 1

    So, you mean that Uncle Jed, the Pig Fu&*er is on the cutting edge of genetic evolution, and ensuring plenty of 'horizontal gene transfer'?

  82. Example of this by JTsyo · · Score: 1

    http://www.msnbc.msn.com/id/34824610/ns/technology_and_science-science/?GT1=43001
    The sneaky slugs seem to have stolen the genes that enable this skill from algae that they've eaten. With their contraband genes, the slugs can carry out photosynthesis — the process plants use to convert sunlight into energy.

  83. Creationists are reading this article by jmbeck15 · · Score: 0

    ...to see if this news bodes well for them, and then reading these comments, to see if someone here can spin it to fit.

  84. Lateral Transfer In Humans? by Anonymous Coward · · Score: 0

    Proposed gene therapy technologies (directly inserting new/effective copies of genes into human genomes for therapeutic reasons) would amount to a - albeit engineered - form of lateral gene transfer.
    We (humans) would then be subject to a complex and currently unpredictable hybrid of horizontal and vertical evolution.

  85. What is non-Darwinian about this? by tgibbs · · Score: 1

    Darwin never specified how inheritable traits arise. He knew nothing of genes, other than that his theory required the units of inheritance to be discrete. So whether or not genes are transferred horizontally has nothing to do with whether it is Darwinian evolution. The key issue is whether organisms that acquired the trait tended to propagate more successfully and pass the trait onto their descendants, thereby increasing the frequency of that trait in the population. If that is the case, then it is Darwinian evolution.

    It's certainly true that many modern scientists have tended to assume that the major source of genetic generation of diversity was spontaneous mutations in an organisms DNA, but the idea of a contribution from gene transfer is not itself particularly novel.

  86. Programming Consequences by Anonymous Coward · · Score: 0

    Time to dump OOP inheritance hierarchies and all those cute little animal training examples and replace it with set theory. No wonder my classes grew so messy over time. In the real world, features are promiscuous.

  87. blasphemy! by steak · · Score: 1

    the word of darwin is set in stone and is a sacrosanct theroy. any work that seeks to alter the theroy of evolution is a violation of holy science.

    troll out

  88. Survival of the Fittest Gene by Tablizer · · Score: 1

    Maybe it's a matter of semantics, but a better model may be to consider evolution of genes instead of evolution of individuals. In other words, survival of the fittest gene. Even in human populations, we tend to protect relatives because they share many of the same genes as we do as an individual. A pure individual focus wouldn't bother with this.

    Instead, it's genes fighting for supremacy less so than individuals. It's still Darwinian evolution, just not individualian (sic?) evolution. Darwin got the process right, just not quite the scope or boundary. The unit of survival is a smaller scale than individual.

    By the way, I've read an article that shows evidence that the design of the mammalian placenta is possibly a result of non-mammalian genes being introduced by viruses. Viruses often try to disable the host immune system in order to spread themselves better. But the mammalian placenta needs a similar mechanism to avoid having mother's immune system attack a fetuses' cells but still transfer nutrients, being that the baby's cells are "foreign" from the mother's immune system's perspective.

    Rather than reinvent a mechanism from scratch to induce mother-child immunity suppression, mammals inadvertently borrowed a virus's mechanism and that mechanism is with us today. They recognize it as being from a virus because it's surrounded by virus-like genetic idioms (most of which are not used via biological analogs of Go To jump-overs). Thus, our ancestors stole "ideas" from viruses. We are all part virus. Boogady Boogady!

    Are your base pairs are belong to me!
         

  89. It was a sea slug by Benfea · · Score: 1

    Not a snail, a sea slug: http://www.msnbc.msn.com/id/34824610/ns/technology_and_science-science/?GT1=43001 And yeah, this was the second thing I thought of when "horizontal gene" was brought up (mitochondria being the first).

  90. Your math is wrong by Benfea · · Score: 1

    I've heard all of the "evidence" for the existence of this or that magical sky faerie, and all of it is less credible than the evidence of people who claim to have been kidnapped by aliens and subjected to anal probes. Rejecting an idea that has zero evidence does not make one crazy.

    On the other hand, believing in the Talking Snake Theory of Creation despite zero evidence for the Talking Snake Theory and despite massive amounts of evidence for evolution, big bang, etc., is very much insane.

  91. Huh? Something's wrong here. by Hurricane78 · · Score: 1

    Carl Woese, one of whose earlier discoveries was the third branch of life on Earth, the Archaea.

    Uum, H.P. Lovecraft already mentioned Archaea in his “Mountains of Madness” story. So unless Carl Woese is doing science since 1931, I have to doubt this statement...

    --
    Any sufficiently advanced intelligence is indistinguishable from stupidity.
  92. Comment removed by account_deleted · · Score: 1

    Comment removed based on user account deletion