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A Genetically Engineered Fly That Can Smell Light

An anonymous reader writes "It sounds like a cool — if somewhat pointless — super-powered insect: a fly that can smell light! Researchers added a light-sensitive protein to a fruit fly's olfactory neurons, which caused the neurons to fire when the fly was exposed to a certain wavelength of blue light. Adding the protein specifically to neurons that respond to good smells, like bananas, makes for a light-seeking fly."

111 comments

  1. But can we wipe out pest bugs by making them... by Anonymous Coward · · Score: 0

    ... malfunction genetically?

    1. Re:But can we wipe out pest bugs by making them... by Cryacin · · Score: 4, Funny

      Harry! Harry! Don't look into the light!!!

      I can't help it... it's sooo beautifull!!!!

      zzzzzzzzzttt

      --
      Science advances one funeral at a time- Max Planck
    2. Re:But can we wipe out pest bugs by making them... by Anonymous Coward · · Score: 0

      I can't help it... it's sooo beautifull!!!!

      I think you mean "delicious".

    3. Re:But can we wipe out pest bugs by making them... by Anonymous Coward · · Score: 0

      To infinity, and beyond! *starts flying towards the sun*

    4. Re:But can we wipe out pest bugs by making them... by X0563511 · · Score: 1

      We'd need to make sure they overwhelm the "normal" population fast enough that their dying wouldn't self-select them right out of the gene pool. This is contradictory :)

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
  2. What a wasted opportunity by Shadow+of+Eternity · · Score: 3, Interesting

    They could've made them think a wavelength smells terrible and then sold fly repellant lightbulbs.

    --
    A bullet may have your name on it but splash damage is addressed "To whom it may concern."
    1. Re:What a wasted opportunity by Hazza64 · · Score: 3, Insightful

      No, you see the trick is to get them attracted to light. THEN they will land on those inefficient 80W bulbs attempting to eat it and burn their 'mouths' and feet in the process.

    2. Re:What a wasted opportunity by amicusNYCL · · Score: 4, Insightful

      Right, and all they have to do is genetically engineer all the flies in the world, or at least every population of them.

      --
      "Our two-party system is like a bowl of shit looking at itself in a mirror." - Lewis Black
    3. Re:What a wasted opportunity by AK+Marc · · Score: 4, Funny

      Well? I'm waiting.

    4. Re:What a wasted opportunity by tpwch · · Score: 2, Interesting

      Well think about it. How many generations does it take for a favorable gene to spread trough the population? Give the flies another favorable gene as well as the smell gene, then set them loose to make babies. I read somewhere that it takes 3000-5000 years for humans, but fly generations are much shorter, so maybe we could reap the advantages in our lifetime.

      --
      Posted by a Debian GNU/Linux user
    5. Re:What a wasted opportunity by R3d+M3rcury · · Score: 3, Funny

      That's for favorable genes. I believe that, from the fly's point-of-view, believing that blue light is food (and potentially causing it to fly into a human-produced trap) would be all that favorable.

    6. Re:What a wasted opportunity by kabloom · · Score: 1

      That's why he thinks that a fly-repellant-light gene would fare better.

    7. Re:What a wasted opportunity by EdIII · · Score: 2, Insightful

      You're thinking about it all wrong.

      You set up fly traps that repel the genetically modified flies. What you end up with is flies that are genetically predisposed to stay away from the areas we designate. Assuming the genetic modifications don't have any other adverse affects I would say it would be a great idea. We could have a situation develop where flies stay away from us and yet are still part of the environment and the food chain.

    8. Re:What a wasted opportunity by nametaken · · Score: 1

      I'm gunna go out on a limb and guess this new suicide breed will not overtake the existing non-suicidal flies in the process of natural selection. Call me Nostradamus. ;)

    9. Re:What a wasted opportunity by mr_mischief · · Score: 1

      Sorry, but the name "Nostradomus" is also taken.

    10. Re:What a wasted opportunity by Anonymous Coward · · Score: 0

      Or they could make them attracted to infrared.
      Then release them on a country you don't particularly like.
      They either attempt to fly to the sun or fly to the next closest thing, humans.

      The next new super-weapon has now been born.
      Better yet, make them attracted to a crop colors.

      Of course, it then becomes a problem when they superbreed to huge numbers.
      But as always, we just make a bigger, more powerful fly to destroy those ones.
      And so on, and so on.

    11. Re:What a wasted opportunity by Anonymous Coward · · Score: 0

      Hmmm! They like the "Blue Light Special" sales or is that "Blue plate special" at the garbage dump!

    12. Re:What a wasted opportunity by tpwch · · Score: 1

      Which is why I wrote that they should insert another favorable gene as well, to increase the chances of those individuals genes being spread.

      --
      Posted by a Debian GNU/Linux user
    13. Re:What a wasted opportunity by Paradigma11 · · Score: 1

      You're thinking about it all wrong.

      You set up fly traps that repel the genetically modified flies. What you end up with is flies that are genetically predisposed to stay away from the areas we designate. Assuming the genetic modifications don't have any other adverse affects I would say it would be a great idea. We could have a situation develop where flies stay away from us and yet are still part of the environment and the food chain.

      Yes, but you would also have to increase the fitness of your engineered flies. make them attracted to a certain wavelength and place nutrition at lamps with this wavelength. also make them sexually compatible, but genetically dominant to the rest of the fly population.

    14. Re:What a wasted opportunity by GundamFan · · Score: 2, Insightful

      Nostradumbass on the other hand is, surprisingly, available.

      --
      I don't give a damn for a man that can only spell a word one way.
      Mark Twain
    15. Re:What a wasted opportunity by mr_mischief · · Score: 1

      You're kidding! I thought that'd be one of the first misspellings to be snatched up, especially on Slashdot!

      Wait... user 205075. You really were kidding.

      Oddly enough, "Nostradomus" actually isn't a Slashdot account despite how often that spelling appears in the comments. I could have sworn it would.

    16. Re:What a wasted opportunity by Crudely_Indecent · · Score: 1

      You're looking at it the wrong way....

      Getting pestered at the campsite? Crack a special-wavelength-blue glowstick and toss it into a neighboring campsite. Go fetch!

      --


      "Lame" - Galaxar
    17. Re:What a wasted opportunity by mhelander · · Score: 1

      How do you couple them, preventing the spread of the one without the other?

    18. Re:What a wasted opportunity by Shadow+of+Eternity · · Score: 1

      And then the gorillas die in winter?

      --
      A bullet may have your name on it but splash damage is addressed "To whom it may concern."
  3. IOW by aBaldrich · · Score: 4, Insightful

    In other words, it can see with its nose.

    --
    In soviet russia the government regulates the companies.
    1. Re:IOW by Kenshin · · Score: 5, Funny

      Next test subject: Toucan Sam.

      --

      Does it make you happy you're so strange?

    2. Re:IOW by by+(1706743) · · Score: 1

      Furthermore, if it were truly "smelling" light, then wouldn't it be able to smell objects obscured from vision (this being a contradiction, barring pathological situations)? As the saying goes, I smell a rat...

    3. Re:IOW by tenco · · Score: 1

      That's the part where "super powered" comes into play.

    4. Re:IOW by Anonymous Coward · · Score: 0

      Well, no. If you actually RTFS instead of just the title, you'll see that it only senses one color. It does not get an image, just the intensity of that one wavelength. It smells light.

    5. Re:IOW by spazdor · · Score: 1

      it can see with its nose.

      Then how does it smell?

      --
      DRM: Terminator crops for your mind!
    6. Re:IOW by RenderSeven · · Score: 2, Funny

      Then how does it smell?

      Terrible! Da dum dum.

    7. Re:IOW by xanadu113 · · Score: 1

      I can do that too, when appropriately lysergically enhanced... =)

      --
      -Myke
    8. Re:IOW by treeves · · Score: 1

      With its ears, of course.

      --
      ...the future crusty old bastards are already drinking the Kool-Aid.
    9. Re:IOW by Gaffod · · Score: 0

      The olfactory system recognizes substances based on their chemical characteristic, mostly molecule shape. "Light", or photons carrying it, have no molecule shape or chemical characteristic, not in the sense of interacting with olfactory receptor proteins at any rate. You can't smell light. That's like saying I can "see" pain when someone jabs a spike in my eye.

  4. How can they distinguish from normal behavior? by Anonymous Coward · · Score: 0

    I mean, flies are attracted to light already.

    1. Re:How can they distinguish from normal behavior? by h4rr4r · · Score: 2, Insightful

      They put little blindfolds on them, obviously.

    2. Re:How can they distinguish from normal behavior? by nut · · Score: 1

      Correct. Flies are already light-seeking diurnal creatures. If you want a fly to fly out of the house at night, turn on the porch light and turn off the inside lights.

      I hope they corrected for this in their experiment - and I also wonder how they did it.

      --
      Never trust a man in a blue trench coat, Never drive a car when you're dead
    3. Re:How can they distinguish from normal behavior? by RadioElectric · · Score: 1

      Yeah, if only there were some place where scientists would publish their research saying exactly what they did and what they found.

      They did account for that.

  5. Great Work by Nuskrad · · Score: 5, Funny

    Great work guys. You just invented moths.

    1. Re:Great Work by WindShadow · · Score: 2, Funny

      There goes the patent, clearly prior art.

    2. Re:Great Work by haxney · · Score: 2, Funny

      No, they invented drugs for flies. If you really want to smell light, head down to your local acid dealer.

  6. Great news by roman_mir · · Score: 3, Funny

    Finally, we have been able to achieve what we always needed: flies that can compete with human art critics.

    On the other hand these flies are not as advanced as Arizona lawmakers, who apparently can feel if one is an illegal alien by 'looking at brands of shoes' (incidentally, will this not force the cops to hire a disproportional number of gays into service?)

    1. Re:Great news by Brad1138 · · Score: 1

      "Arizona Lawmakers"

      Nation wide ~65% approval rating for Arizona law, 70+% approval not counting Hispanics.

      --
      If you could reason with religious people, there would be no religious people
    2. Re:Great news by Anonymous Coward · · Score: 1

      Slavery had great approval ratings for a long time. I take it you supported that, as well?

    3. Re:Great news by rollercoaster375 · · Score: 1

      Why on earth would you not count hispanics?

    4. Re:Great news by Idiomatick · · Score: 1

      The law is racist, he's just trying to be consistent.

    5. Re:Great news by Brad1138 · · Score: 1

      Slavery had great approval ratings for a long time. I take it you supported that, as well?

      No, I support people who are here illegally being sent back home so they can get legitimately. There is absolutely no correlation with slavery. Why do people have a problem with punishing people for breaking the law. Try to sneak into Mexico and see how you are treated, you will probably end up dead.

      --
      If you could reason with religious people, there would be no religious people
    6. Re:Great news by Brad1138 · · Score: 1

      Why on earth would you not count hispanics?

      Because in Arizona, the vast majority of illegals are Hispanics. Obviously they aren't going to vote against themselves, they skew the results.

      --
      If you could reason with religious people, there would be no religious people
    7. Re:Great news by Brad1138 · · Score: 1

      How is the law racist? If you are here ILLEGALLY you have done something ILLEGAL and should be punished for it. Moron.

      --
      If you could reason with religious people, there would be no religious people
    8. Re:Great news by Idiomatick · · Score: 1

      AFAIK it isn't illegal to be hispanic.

  7. Smell-o-vision by Brad1138 · · Score: 1

    Smell-o-Vision, here we come...

    --
    If you could reason with religious people, there would be no religious people
    1. Re:Smell-o-vision by hort_wort · · Score: 1

      Yeah yeah, but for now we have to ask flies what the sexy girl pictures smell like.

      "Hey Harvey, what about this one?"
      *Bzzzztttttt*
      "Bananas you say? I figure she'd be more strawberries than bananas."

    2. Re:Smell-o-vision by EdIII · · Score: 2, Funny

      "Bananas you say? I figure she'd be more strawberries than bananas."

      Harvey was doing you a solid.

      I would much rather steer towards the girls associated with strawberries than the "girls" associated with bananas.

  8. Next up... by PirateBlis · · Score: 0

    ... I will create a Moquito that can see farts! Thus ending the age old question of "Who dealt it?"

  9. Someone said it before ;) by Longjmp · · Score: 4, Funny

    Time flies like an arrow, fruit flies like a banana. heh.

    --
    There are fewer illiterates than people who can't read.
    1. Re:Someone said it before ;) by vashfish · · Score: 0, Redundant

      Buffalo buffalo Buffalo buffalo buffalo buffalo Buffalo buffalo Hooray for ambiguity

  10. Flies that eat oil by Anonymous Coward · · Score: 0

    Just think if we could develop flies that eat oil. That'd clean up the gulf spill... and then some!

  11. Waste of money by miggyb · · Score: 1

    I could have done that same research with $200 worth of drugs.

    --
    This signature serves no purpose other than to help you see which posts were made by me.
    1. Re:Waste of money by Anonymous Coward · · Score: 0

      OH SHIT HOMEY
      WEEDE LEAFES AMIRIGHT?
      filtering filtering filtering filtering

  12. Ok then.... by 3seas · · Score: 1

    ... The Fly: help me, help me. I'm so hungry and light is not filling.

    1. Re:Ok then.... by mr_mischief · · Score: 1

      They should have made it a flavor rather than a scent. Then they could license it to Miller Brewing.

  13. Close... by toppavak · · Score: 1

    It would be more accurate to say that the flies perceive light that falls on those receptors fairly non-specifically as smell. To 'see' implies perception of light, but the lack of optics and the low-level organization that exists in photoreceptors, it's unlikely that the flies can perceive anything more detailed than a burst of smell when a light comes on.

  14. Did it put you whippersnappers in your place? by Anonymous Coward · · Score: 0

    I guess now we know how the smelloscope works ...

    1. Re:Did it put you whippersnappers in your place? by Anonymous Coward · · Score: 0

      I was disappointed that there was no "goodnewseveryone" tag.

  15. Problem now is by fustakrakich · · Score: 1

    they can't smell shit from shinola

    --
    “He’s not deformed, he’s just drunk!”
  16. So Fricken Laser Guided.... by sbeckstead · · Score: 1

    So what you are saying here is that if we can make an explosive small enough we can create laser guided flies that will seek out the spot and land and detonate. Should be good for taking off a nose or ear at least. Better yet a human only skin absorb-able poison that you can dip the fly into then give the target a coating of that light. Bingo one dead target and the murder weapon wings it way to oblivion.

    1. Re:So Fricken Laser Guided.... by Jeremi · · Score: 1

      So what you are saying here is that if we can make an explosive small enough we can create laser guided flies that will seek out the spot and land and detonate.

      Wouldn't they be more likely to fly towards the laser's source? Probably not what you want....

      --


      I don't care if it's 90,000 hectares. That lake was not my doing.
    2. Re:So Fricken Laser Guided.... by sbeckstead · · Score: 1

      The laser's source is largely invisible, while the reflected light from the surface of a person's skin has been tinged to a slightly different wavelength and made less coherent, this is the wavelength you tune the fly to.

  17. New movie line by gyrogeerloose · · Score: 3, Funny

    "I love the smell of blue in the morning..."

    --
    This ain't rocket surgery.
  18. I for one, too by zooblethorpe · · Score: 1

    Well, I, for one, am busy trying to figure out where the light blue bananas are...

    Cheers,

    --
    "What in the name of Fats Waller is that?"
    "A four-foot prune."
  19. Smile away! by Yo,dog! · · Score: 1

    Man, I could smell your feet a mile away!
    Smile away!

    1. Re:Smile away! by Dragoniz3r · · Score: 1

      Smelly action at a distance.

  20. Seeing is perceiving by RobinEggs · · Score: 1

    It's not like "sight" and "smell" go into totally separate processing units along totally separate conductors: both signals still went through a nerve and into a little fly brain.

    All they did was get a perception of light to travel into the brain on a different bundle of almost identical nerves. What's the big deal? Haven't these people ever seen the Matrix? If you perceive it, you perceive it; for most purposes it doesn't make a damn bit of difference how the perception got into your brain.

    1. Re:Seeing is perceiving by ZeroExistenZ · · Score: 1

      it doesn't make a damn bit of difference how the perception got into your brain.

      brb, getting some perception in my brain with a pole.

      --
      I think we can keep recursing like this until someone returns 1
    2. Re:Seeing is perceiving by Anonymous Coward · · Score: 0

      brb, getting some perception in my brain with a pole.

      EXPERIMENT EXECUTED SUCCESSFU! You gained perception of pain in your brain.

  21. Bonus points... by boredsenseless · · Score: 2, Interesting

    if they call it "smision."

  22. I've been lighting farts for years.... by Bob_Who · · Score: 2, Funny

    ...its smells so bright it makes your eyes water.

  23. but.... by santax · · Score: 1

    But... why?

    1. Re:but.... by Anonymous Coward · · Score: 0

      I work in this field. This isn't the first time people have done this stuff.
      With flies and mice we have genetic control of individual neuron types (not just olfactory sensory neurons). This enables us to modify activity of individual neuronal classes. Light activation provides an easy way to make neurons fire. There are also channels available which will suppress firing. The identity of an odour is coded by the pattern of activated sensory neurons. By interfering is subtle ways with that pattern, we can ask how much do we need to change it in order for the odour to be perceived differently.

  24. Hmmm by Anonymous Coward · · Score: 0

    I thought it smelled purple in here

    1. Re:Hmmm by __aatirs3925 · · Score: 0

      If purple can be a flavor, why can't it smell? Well now it can!

  25. Prior art by rwyoder · · Score: 1

    Back in my mis-spent youth, a hit of blotter acid was all we needed to smell light, hear colors, and see sounds.

  26. Re:I for one by PopeRatzo · · Score: 4, Funny

    A fly that can smell light? Big deal.

    My wife says that my feet smell evil.

    --
    You are welcome on my lawn.
  27. So what you're saying.. by tpstigers · · Score: 1

    ..is that the fly got Jeff Goldblum's nose.

  28. What Smells? by Deaths+Proxy · · Score: 1

    * sniffs the air * What smells like blue?

  29. Gene splicing by norppalaho · · Score: 1

    ... but how many asses it has?

    --
    One of the coolest sites, ever: zombo.com
  30. Lame Superpowers by Lord_of_the_nerf · · Score: 1

    .....this is what happens when you let Grant Morrison reboot nature.

  31. Re:I for one by Anonymous Coward · · Score: 0

    haven't you ever heard? see no evil, hear no evil, smell no evil?

  32. geez by Anonymous Coward · · Score: 0

    so many bad jokes.

    but so much time to read....

  33. Re:I for one by denmarkw00t · · Score: 0, Redundant

    Seriously, mod this man UP. I understand that every insect/alien/Ballmer thread has an "I for one" post, but to be labeled redundant as the first of it's kind in a thread is ridiculous.

    I, for one, DO NOT welcome our redundant-modding moderators.

  34. Falling down face first into the confusion by DynaSoar · · Score: 0

    It is an exceedingly idiotic collection of assumptions and ignorance too profound to be able to recognize from the inside. There's not a shred of evidence saying that if a neuron has some perceptual tricera input, the signal would be anything other than the same old fluctuating ion densities. It certainly would not generate a signal part light-responsive and have that push through the neuron that's essentially unrelated. Just as any other increased signal impinging on a neuron causes it to fire more proportionally, I doubt the answer is 'in there'. Ah well, got to get back to work. Have fun.

    --
    "I may be synthetic, but I'm not stupid." -- Bishop 341-B
  35. This is cool but... by Sentrion · · Score: 1

    It would be so much cooler if they embedded a chip in the fly and became the first to transmit a virus from a PC to an insect that smells light. http://idle.slashdot.org/story/10/05/26/1214214/Scientist-Infects-Self-With-Computer-Virus?from=rss&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+Slashdot%2Fslashdot+(Slashdot)

  36. Re:I for one by Anonymous Coward · · Score: 0

    My wife says that my feet smell evil.

    They led you to her didn't they?

  37. Insect zapper by akayani · · Score: 1

    "The company, owned by Apple, has also taken out a patent on a very specific frequency of insect zapper. While apologising for the accidental release of the flies, Jobs restated the company's pledge to make 1billion iZappers which are iLink compatible with your iHouse software. Press Buy Now on your iCare."

  38. Next version, the smell-o-scope! by Anonymous Coward · · Score: 0

    Now all we need is to invent the smell-o-scope so we can smell distent cosmic object. Too bad, Wernstrom would give it "the worst grade imaginable--an A minus minus".

  39. An answer to epistemological questions by Clueless+Nick · · Score: 1

    or a symptom of synaesthesia? Now we will know if orange smells like orange.

    --
    Chat with other atheists http://secularchat.org
  40. That's nothing, I know this guy by ZeroExistenZ · · Score: 1

    I know this engineer who can feel colours: in his experience certain sensations would invoke colours.

    He can't really explain or verbalize it and while he tries to he is at lost for words. When I inquire it's just a "strong association" he insists it's a physical experience and not so much "association".
    You often hear him say "this feels yellow" something in that fashion.

    --
    I think we can keep recursing like this until someone returns 1
    1. Re:That's nothing, I know this guy by Anonymous Coward · · Score: 0

      That'll be 'synaesthesia'.

    2. Re:That's nothing, I know this guy by JLangbridge · · Score: 1

      I knew somebody with that; he could read words, like just about anyone, but each letter had a colour. Fill a whitebord with hundreds of letter "O"s, and add one Q, and he could find it instantly, it was the letter that was a different colour from the rest. His parents remember him saying "Hey, I didn't know you could change the colour of F, just by adding a line!" (i.e. turning it into E). That was their wake up call, and he was diagnosed with synaesthesia a few weeks later.

      --
      The urgent is done, the impossible is on the way, for miracles expect a small delay.
    3. Re:That's nothing, I know this guy by Njoyda+Sauce · · Score: 1
      --

      You can only be young once, but you can be immature forever.
  41. Zap! by flyingfsck · · Score: 1

    Cool, now these flies will head straight to the nearest bug zapper...

    --
    Excuse me, but please get off my Pennisetum Clandestinum, eh!
  42. A wasted opportunity by Anonymous Coward · · Score: 0

    Shouldn't they be working on one which has been engineered to detect a half-open window so they can fly out of it?

  43. SirVirtual by SirVirtual · · Score: 1

    I keeps seeing a little tiny Icarus head on a fly's body flying to the sun crying "help me help meeeeee....."

  44. Philosophical: does it see or smell light? by noidentity · · Score: 1

    Is it smelling light, or seeing it? Is sight the ability of an organism to detect photons hitting it, or simply how an organism perceives some sort of physical stimulus? The latter seems less useful, since it would allow sight, smell, touch to all refer to the same physical stimulus.

  45. Possible Next Project by LifesABeach · · Score: 1

    Maybe work on a therapy that would mend tissue cell DNA, and RNA?

  46. Re:I for one by Anonymous Coward · · Score: 0

    I do.

  47. That's nothing by dbrossard · · Score: 1

    My dad can hear pudding

  48. Fish next by Cstryon · · Score: 1

    Now they need to genetically engineer fish to consume crude oil. It may mess up the future accountability issue, but it sure can save a lot of animal life.

    --
    Indoctrinate : to instruct especially in fundamentals or rudiments Educate : to develop mentally, morally, or aestheti
  49. Dialogue by northernfrights · · Score: 1

    Fly 1: "Whoa man, what smells like fresh bananas? I'm starving"
    Fly 2: "We're flying over a river right now..."
    Fly 1: "I know, do you smell it?"
    Fly 2: "Dude, how much dog s*** did you eat last night?"

  50. small thinking by electrosoccertux · · Score: 1

    That's a great idea, then it never comes to market because the university owns the patent and they want too much for the exclusive royalties, if you can even pin them down for such a contract. How are you going to come up with such a document anyways without coughing up all the dough to pay a patent lawyer to write the hundred++ page document? And how are you going to get that dough in the first place. It's much easier to magically wave your hand and say it can happen.

    No, you do what we did, which is what all smart people do, and you write the research paper on something sufficiently interesting to get you grants, but you save the really good ideas for your own startup. We weren't about to give ours away. We'd already given the school 5 years of $30k+ tuition.