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HIV Vaccine Trial Shows 90% Immune Response

fergus07 writes "Researchers at the Spanish Superior Scientific Research Council (CSIC) have successfully completed Phase I human clinical trials of a HIV vaccine in which 90% of volunteers developed an immunological response against the virus. The MVA-B vaccine draws on the natural capabilities of the human immune system and 'has proven to be as powerful as any other vaccine currently being studied, or even more,' says Mariano Esteban, head researcher from CSIC's National Biotech Centre."

246 of 386 comments (clear)

  1. warning! by Cyko_01 · · Score: 1

    link is goatse

    1. Re:warning! by GillyGuthrie · · Score: 1

      parent has dns hijacker installed?

    2. Re:warning! by _0xd0ad · · Score: 1

      No, it's an Aeonity blog hosting Goatse via a bit.ly link. Telnet comes in handy sometimes.

      I also took the opportunity to add a few more AdBlock Plus filters.

      ||bit.ly^$third-party
      slashdot.org#a(href*=/boredgeek)

    3. Re:warning! by X0563511 · · Score: 1

      Can you explain this one for me? I can't parse what it's doing.

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    4. Re:warning! by MightyMartian · · Score: 1

      What the fuck is wrong with you? Did your mother drop you on your head, or are you just a fucking mental case by default? Grow up you infantile halfwit.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    5. Re:warning! by GNUALMAFUERTE · · Score: 1

      No, he's just 14. One day, he'll eventually grow up and feel embarrassed about this.

      --
      WTF am I doing replying to an AC at 5 A.M on a Friday night?
    6. Re:warning! by _0xd0ad · · Score: 1

      Explain what?

      It's a 404 now. Or did you want me to explain one of those filters?

    7. Re:warning! by X0563511 · · Score: 1

      Oh, they are a pair? Makes sense now. I thought they were interacting.

      --
      For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
    8. Re:warning! by slackbheep · · Score: 1

      The world is full of assholes, and at best giving them the attention they crave makes you an idiot, at worst it paints a target on your back. Just... throwing that out there.

  2. Re:90% chance that prostitue won't kill you by BradleyUffner · · Score: 5, Insightful

    Healthy relationships would kill HIV 100%, not 90.

    Meanwhile, back in reality....

  3. Re:But will it able to cure by Anonymous Coward · · Score: 1

    this?

    idiot.

  4. Great by G-News.ch · · Score: 1

    That's great. This combined with existing anti-retroviral therapies might actually extinguish HIV from the face of the earth in only a few decades, if used widely.

    1. Re:Great by AmazinglySmooth · · Score: 5, Funny

      Abstinence, combined with existing anti-retroviral therapies might actually extinguish HIV from the face of the earth in only a few decades, if used widely.

    2. Re:Great by magsol · · Score: 3, Insightful

      Good luck with abstinence being "used widely".

      --
      "I'd just like to emphasise that taking a million years isn't a metaphor here..." -Rich Bradshaw
    3. Re:Great by sulimma · · Score: 5, Insightful

      Abstinence will actually extinguish the whole human race from the face of the earth in only a few decades, if used widely.

    4. Re:Great by Colonel+Korn · · Score: 1

      Abstinence, combined with existing anti-retroviral therapies might actually extinguish HIV from the face of the earth in only a few decades, if used widely.

      If you want to discuss fairy tales, similarly probable is that quantum mechanics will allow all the HIV to tunnel its way off the planet at the same moment.

      --
      "I zero-index my hamsters" - Willtor (147206)
    5. Re:Great by ani23 · · Score: 1

      are the guys advocating abstinence trolls, serious or just ones who cant get any?

    6. Re:Great by Riceballsan · · Score: 3, Insightful

      Abstinance alone, on a global scale in roughly one century can whipe out aids, cancer and every other disease from the human race, even solve world hunger and the economy.

    7. Re:Great by medv4380 · · Score: 5, Informative

      I'd be learly of this until Phase II and Phase III are completed. Developing an Immune response is different then having a successful vaccine. The antibodies have to be ones that will help in eradicating the infection, and since HIV mutates so rapidly there is no grantee that it will work long term in world wide eradication.

    8. Re:Great by Americano · · Score: 1

      Abstinence would also... extinguish humanity from the face of the earth within only a few decades, if used widely, too!

      Or did you forget that:
      1) not everybody contracts aids from sex, and so it will still be able to spread via IV drug use, perinatal transmission, and nonsexual contact with the blood of infected people;
      2) humans reproduce using sex;

      Or did you have data to share that demonstrates that the sole cause of AIDS is losing your virginity outside of marriage?

    9. Re:Great by Belial6 · · Score: 1

      Well, sure, if there are no humans, there will no be AIDS in humans.

    10. Re:Great by DriedClexler · · Score: 2

      Can I be the one who injects people with HIV (the virus that causes AIDS) to test out their immune response?

      --
      Information theory is life. The rest is just the KL divergence.
    11. Re:Great by Barefoot+Monkey · · Score: 1

      Abstinence, combined with existing anti-retroviral therapies might actually extinguish HIV from the face of the earth in only a few decades, if used widely.

      Abstinence, whether-or-not combined with existing anti-retroviral therapies, might actually extinguish humanity from the face of the earth in only a few decades, if used widely enough.

    12. Re:Great by king+neckbeard · · Score: 1

      Unfortunately not. Technology has allowed people to have children without having sex.

      --
      This is my signature. There are many like it, but this one is mine.
    13. Re:Great by HBI · · Score: 1

      I'd substitute "forced sterilization" for the abstinence. Once effective tests for diseases with at least a component of genetic transmission are commonplace, someone's going to bring this up. Best warm up the ethical arguments now against this, we'll need them.

      --
      HBI's Law: Frequency of calling others Nazis is directly correlated with the likelihood of the accuser being Communist.
    14. Re:Great by 93,000 · · Score: 1

      Reminded me of : "There are no more elephants. There is also no more unethical treatment of elephants." Flight of the Conchords

    15. Re:Great by Cryacin · · Score: 1

      Here's hoping that the crazy zealot religious types follow their own advice and stay abstinent then. But I guess that's too much to hope for.

      --
      Science advances one funeral at a time- Max Planck
    16. Re:Great by medv4380 · · Score: 1

      So you're the one who shut down the Hollywood Porn industry last month.

    17. Re:Great by Dahamma · · Score: 1

      This *is* Slashdot, so likely all three...

    18. Re:Great by Nadaka · · Score: 1

      Abstinence, if used widely enough would also wipe humans from the face of the earth in less than 10 decades.

    19. Re:Great by Baloroth · · Score: 1

      I wouldn't mention abstinence on /. Most of the people around here are unwillingly abstinent and a little sore about it.

      --
      "None can love freedom heartily, but good men; the rest love not freedom, but license." --John Milton
    20. Re:Great by hedwards · · Score: 2

      IV drug use is something that people can avoid. And it's pretty unusual for folks that aren't working as EMTs, military personnel or similar to come into contact with random blood. And in the case of the military, having HIV is automatic grounds for not being allowed to enlist. I would assume that it's grounds for discharge.

      As for reproduction, it's not an issue, you only need to have sex with one person for that to happen. And ultimately, if everybody did have sex with precisely one partner or had the appropriate testing done, you wouldn't see HIV routinely being spread via sex.

      You might still have some cases popping up, but a virus needs a certain number of new infections to keep from being quarantined or otherwise die out.

    21. Re:Great by halivar · · Score: 1

      No, no, it's different than, not dufferent than.

    22. Re:Great by medv4380 · · Score: 1

      Are you sure it's not thæn?

    23. Re:Great by Xenkar · · Score: 1

      Forced sterilization of everyone with genetic diseases pretty much means sterilization of the entire species since there is always some genetic disease in a person, hiding as a recessive gene. Just remember that when they start their little crusade to wipe out diseases.

      (Disclaimer: I have Hemophilia B, Osteochondroma, and genetic predispositions to various mental disorders, which means I'm near the top of the list of peeps who'll get sterilized.)

    24. Re:Great by HBI · · Score: 1

      Type 1 diabetes here. I already reproduced, so a non-issue for me.

      --
      HBI's Law: Frequency of calling others Nazis is directly correlated with the likelihood of the accuser being Communist.
    25. Re:Great by jizziknight · · Score: 1

      Celibacy would be a more correct term than abstinence for what you and the parent poster are implying. I think abstinence typically refers to something more temporary, like chastity.

      --
      Everything I say is a lie. Except that... and that... and that, and that, and that, and that... and that.
    26. Re:Great by bky1701 · · Score: 1

      Abstinence can also cure cancer, if we can get everyone on board. Wonder why that hasn't been tried!

    27. Re:Great by medv4380 · · Score: 1

      I would assume that it's grounds for discharge.

      In 1998 in the US the answer is No. HIV is not grounds to be discharged. Heck, in the 90's you'd probably have even made it though enlistment and be HIV positive. They did make sure that they were in non critical jobs. The med requirment to keep it in check basically means you cant put them on front line duty. The GOP had a big argument about it in the 90's about trying to force the military to discharge them. I don't know what ultimatly became of that or if their rules currently apply. You're free to shuffle though the manuals to find out if you'd like to now definitively. Though whether or not our soldiers are clean is irrelevant if it's not the case of all soldiers since I doubt we do exclusive killing of our own men.

    28. Re:Great by somersault · · Score: 5, Funny

      It'll work fine if people teach it to their kids, grandkids, great grandkids and so on.

      --
      which is totally what she said
    29. Re:Great by pixelpusher220 · · Score: 1

      or is it that the 'little sore' is why they are unwillingly abstinent? ;-)

      --
      People in cars cause accidents....accidents in cars cause people :-D
    30. Re:Great by NatasRevol · · Score: 1

      If there was ever a bigger whoosh....

      --
      There are two types of people in the world: Those who crave closure
    31. Re:Great by mooingyak · · Score: 1

      It's okay to be a little dufferent sometimes.

      --
      William of Ockham had no beard. The most likely explanation is that it was chewed off by squirrels every morning.
    32. Re:Great by wierd_w · · Score: 1

      Same here.

      Aunt has epillepsy, mom and uncle have hypoglycemia and type 1 diabetes respectively, dad has 3 of 4 genes for hematochromatosis (a reasonably rare condition causing the body to sequester lethal levels of iron), my sister has S protien deficiency, and my brother is sterile and has dislexia.

      When it comes to the genetic lottery, I pretty much lost. (While never diagnosed, I also exhibit many signs of having fairly pronounced aspergers, but I don't feel that it inhibits my daily life. I just think other people are batshit crazy.)

      I feel that the better solution is to do the world a favor and not purpetuate the already large collection of dangerous recessives I seem to carry. Can I get an honorable mention for the darwin award?

    33. Re:Great by Random+Destruction · · Score: 1

      +1 funny

      --
      :x
    34. Re:Great by BJ_Covert_Action · · Score: 1

      As for reproduction, it's not an issue, you only need to have sex with one person for that to happen.

      What a boring shitty fate for the human race. I'd rather die of AIDS then spend 80 years on this Earth and only fuck one person. God bless freedom. :D

    35. Re:Great by MysteriousPreacher · · Score: 2

      He's not lying. Sex with his wife is great!

      --
      -- Using the preview button since 2005
    36. Re:Great by couchslug · · Score: 1

      "are the guys advocating abstinence trolls, serious or just ones who cant get any?'

      The three are not mutually exclusive.

      --
      "This post is an artistic work of fiction and falsehood. Only a fool would take anything posted here as fact."
    37. Re:Great by Toonol · · Score: 1

      Than, then? So then than?

    38. Re:Great by Firehed · · Score: 1

      That was the joke (also, yes it has - look up IVF). Eliminate humans and their problems also disappear.

      --
      How are sites slashdotted when nobody reads TFAs?
    39. Re:Great by Firehed · · Score: 1

      Ugh, it seems that standing at the DMV all day has impaired my reading ability. Disregard that.

      --
      How are sites slashdotted when nobody reads TFAs?
    40. Re:Great by couchslug · · Score: 1

      The plural of "anecdote" is not "data".

      --
      "This post is an artistic work of fiction and falsehood. Only a fool would take anything posted here as fact."
    41. Re:Great by MightyMartian · · Score: 1

      No it won't. Look at pregnancy rates in the US Bible belt. Abstinence-only education is a failure.

      Kids have sex. They have been having sex for millions of years, and they will continue to have sex. Unless you plan on forcing them all to wear chastity belts, your plan has already been proven wrong.

      Have any other bright ideas?

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    42. Re:Great by MightyMartian · · Score: 1

      Bully for you. You are aware, i trust, that anecdotal evidence is pretty much worthless, and judging by the behavior of many even in areas where abstinence-only education is the norm, you're very likely atypical.

      Public health issues should be resolved by reason and by what actually happens on the ground, not by the mad imaginings of people caught in the midst of their own self-delusions. You know, sort of like all those good religious parents who stuff wool in their childrens' ears so they don't here the actual facts about sex and how to prevent unwanted pregnancies and STDs, so they ignorant kids can go out, do the naughty anyways (after all, that's what kids do, whether they think God will piss in their Wheaties or not), and get pregnant or get itchies in their critchies.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    43. Re:Great by Yo+Grark · · Score: 1

      If your parents never had kids, chances are neither will you. :)

      - Yo Grark

      --
      Canadian Bred with American Buttering
    44. Re:Great by geekoid · · Score: 1

      Because no one has AIDS?

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    45. Re:Great by geekoid · · Score: 1

      No you wouldn't. Ask anyone dying of AIDS.
      As you lay there, alone and cold, the lights dimming, cold sweats send shills, miserable as the worse flu, day in day out for months. The you can tell me it was worth it.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    46. Re:Great by geekoid · · Score: 1

      hollo?! testing , testing...

      This is the 21st century calling, you don't need to have sex with ANYONE to reproduce.

      That is all.

      What a stupid, not practical, shown to not work examples of shit you post is.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    47. Re:Great by dintech · · Score: 1

      He's posting on Slashdot. Abstinence is a given. Unfortunately.

    48. Re:Great by Ocker3 · · Score: 1

      Reminds me of the Catholic Priest who got into the business because his father was one, as was his grandfather...

    49. Re:Great by bragr · · Score: 1

      Not many people die of AIDS these days, not in the developed world. The meds have gotten so good that its quite possible to suppress the virus to the point that the virus is undetectable, the person isn't infectious, and the person has normal white blood cell counts. You can stay that way for decades now, and it isn't uncommon for people to contract HIV and die of something unrelated years later. Not to say that I'll be lining up to have unprotected sex with someone with HIV, but we aren't in the 1980's anymore.

    50. Re:Great by jd2112 · · Score: 1

      If your parents never had kids, chances are neither will you. :)

      - Yo Grark

      Unless you were adopted.

      --
      Any insufficiently advanced magic is indistinguishable from technology.
    51. Re:Great by magsol · · Score: 1

      I do it for the mod points :)

      --
      "I'd just like to emphasise that taking a million years isn't a metaphor here..." -Rich Bradshaw
    52. Re:Great by Artifakt · · Score: 1

      Sex with my ex-wife is the bet sex I've ever had, although it was pretty damned good when we were still married too (just less frequent than it is these days). I was married 23 years, and have been in a monogamous relationship with the same woman for 29 years now.

      --
      Who is John Cabal?
    53. Re:Great by JonySuede · · Score: 1

      You don't have to inject the virus, you just have to inject gays users of crystal meth users. http://virtualmentor.ama-assn.org/2005/12/ccas3-0512.html.

      --
      Jehovah be praised, Oracle was not selected
    54. Re:Great by somersault · · Score: 1

      I have an idea for an anti-whooshing device. I'll let you in on the beta test as you seem like a good candidate for it improving your quality of life.

      --
      which is totally what she said
    55. Re:Great by dunkelfalke · · Score: 1

      That's not how it works. Even an adopted person had, at some point of its life, parents in the biological sense of the word.

      --
      "It's such a fine line between stupid and clever" -- David St. Hubbins, Spinal Tap
    56. Re:Great by Nadaka · · Score: 1

      I noticed this. I wouldn't mind being able to mod myself redundant after I saw everything else that was posted.

    57. Re:Great by tehcyder · · Score: 1

      I have an idea for an anti-whooshing device. I'll let you in on the beta test as you seem like a good candidate for it improving your quality of life.

      You'll have to speak up, he can't hear you over the massive whooshing sound above his head.

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    58. Re:Great by tehcyder · · Score: 1

      are the guys advocating abstinence trolls, serious or just ones who cant get any?

      Yes, the correct answer is number four "it's a fucking joke".

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    59. Re:Great by tehcyder · · Score: 1

      Congratulatins, you are the 100th person to make exactly the same response in this hread to what was obviously a joke.

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    60. Re:Great by tehcyder · · Score: 1

      Abstinence is what my wife and I practiced until our wedding night. Our marriage is great.

      That's not what she said last night...

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    61. Re:Great by tehcyder · · Score: 1

      I wouldn't mention abstinence on /. Most of the people around here are unwillingly abstinent and a little sore about it.

      Vaseline is your friend in these circumstances.

      --
      To have a right to do a thing is not at all the same as to be right in doing it
    62. Re:Great by black+soap · · Score: 1

      It would probably be easier to get widespread testing and awareness worldwide than to get people to stop having sex. Easier, as in "just this side of impossible," as people are incredibly hard to educate.

    63. Re:Great by Fujisawa+Sensei · · Score: 1

      Looks at how successful Mrs Teach abstinence only Sara Palin was with her daughter.

      And that's typical, just look at Texas.

      If you look at the Bible, its been taught since the OT. Its never worked.

      --
      If someone is passing you on the right, you are an asshole for driving in the wrong lane.
  5. Re:90% chance that prostitue won't kill you by cachimaster · · Score: 2

    That's not the way vaccines work. If the prostitute is also vaccinated (very likely) probabilities compound and you have 90%*90% = 99% chance that prostitute won't kill you.

  6. Re:90% chance that prostitue won't kill you by magusxxx · · Score: 1

    Thank you, June. Now go fix Wally and the Beaver their dinner.

    --
    Care killed the cat, but satisfaction brought it back.
  7. Re:90% chance that prostitue won't kill you by cpotoso · · Score: 2

    I wish I had modpoints to mod you up. Indeed, fantasyland is just that...

  8. Re:90% chance that prostitue won't kill you by ShavedOrangutan · · Score: 1

    I don't understand why the concept is so difficult. There is a 100% effective way to prevent catching HIV. Don't have sex with someone who has it! Why is that so unrealistic?

    --
    Godaddy is a scam and a ripoff.
  9. Re:90% chance that prostitue won't kill you by kimvette · · Score: 1

    Well, yeah, aside from tainted transfusions, blood contact from sports injuries, at dentists, unlicensed back-alley tattoo shops, or giving first aid to an infected person, as well as the small (some tiny nonzero) possibility of contracting HIV through hard surfaces such as toilet seats, as well as contracting HIV from the mother (yes, there are babies born with HIV) - and let's not forget idiots who shoot up and even more moronically share needles. Aside from those few? Sure, healthy relationships will prevent 100% of HIV/AIDS cases. Oops, we forgot another one: your BF or GF is a windower/widow and his or her spouse was infected, and didn't know, and you don't know, so in your healthy relationship you contract HIV. But yeah, healthy relationships will be a 100% iron-clad guarantee that HIV will be vanquished over the course of a single generation, so let's not devote resources toward finding a cure or preventive vaccine.

    At least, that is your opinion now, until you're a car accident victim and are treated by an infected EMT, or an infected doctor, or are tattooed by an artist who is violating all kinds of health codes by putting ink back into the bottle for reuse, or you happen to be the unfortunate soul who proves that the infinitesimal chance of contracting HIV from a toilet seat isn't so improbable after all, or until you found your wife's previous partner had HIV and it has been incubating in her body but when you got your marriage license she still tested clean, or your dentist is infected and infects you, then, suddenly, you won't be such an ass and will see the good sense of spending money to protect the responsible folks from the sluts and the drug users, and even from the innocents (EMTs, men and women who have been cheated on, doctors, etc.) who may be harboring the infection.

    Contrary to your belief, not everyone with HIV is a reckless intravenous-drug-using slut. The idea is to protect everyone from the disease because there are too many opportunities for the responsible to contract the disease from the reckless.

    --
    The Christian Right is Neither (Christian nor right). See: Matthew 23, Matthew 25, Ezekiel 16:48-50
  10. 10% by tesdalld · · Score: 1

    sooo.... what happened to the other 10 percent? They all got HIV? That would suck.

    1. Re:10% by DriedClexler · · Score: 1

      I thought the "inert version of the virus" was the vaccine?

      --
      Information theory is life. The rest is just the KL divergence.
    2. Re:10% by pixelpusher220 · · Score: 1

      A friend of mine who is an *actual* doctor said the available documentation on the risk of transmission from female to male is about 3 in 1000. Which is pretty decent odds for completely unprotected sex.

      --
      People in cars cause accidents....accidents in cars cause people :-D
    3. Re:10% by Jarik+C-Bol · · Score: 4, Interesting

      I was curious about this, so i did some reading on other vaccine trials.
      turns out, they are not looking for you to not/get the disease, they are looking for you to develop successful antibodies. (which they can test by taking a blood sample, and infecting it and watching under a microscope).
      Additionally, 90% seems to be the benchmark for a useable vaccine. For example, the final tests for some of the Polio vaccines resulted in 90%ish of the test subjects developing antibodies. After that, its basically a war of attrition on the disease.
      If 90% of a population becomes immune, the chances of the disease spreading within it diminishes accordingly. Eventually, all live carriers die of old age or the disease, and no new carriers are produced, thus eliminating the disease from the population. Heck, even a 55 % successful vaccine could do this, it would just take longer.

      --
      I've decided to Diversify my Holdings. I've divided my cash between my left and right pockets, instead of all in one.
    4. Re:10% by cplusplus · · Score: 1

      *sigh* no mod points. +1 Informative! Hip hip hooray!

      --
      "False hope is why we'll never run out of natural resources!" - Lewis Black
    5. Re:10% by _0xd0ad · · Score: 1

      It is, but that doesn't work with AIDS because it targets the immune system.

      When you get a viral infection, the immune system doesn't target the virus itself; rather, it targets and destroys the infected cells. This prevents them from producing any more copies of the virus. But when it's the immune system being infected, it ends up killing itself, hence the name "auto-immune disease".

      A vaccine works by infecting cells with an inert virus that makes the cell appear infected, but doesn't mass-reproduce itself or have significant ill effects on the patient. The immune system randomly produces a variety of antibodies, each of which targets some specific type of abnormal cell. Eventually an immune cell that has the antibody which detects the infected cells comes along and kills them. Then it starts mass-producing that antibody so the immune system will detect and kill that infection faster in the future.

      If you tried to vaccinate against AIDS, you'd just end up killing off the patient's immune system - and since immunity is carried within the immune system itself, you've killed off the cells that were supposed to detect the infection in the future and subdue it before it got out of hand. The bone marrow will rebuild the immune system, but the new generation of cells don't know what they were supposed to be targeting because the cells with the antibodies targeting cells with AIDS were all killed off with the rest of the immune system.

    6. Re:10% by Carnildo · · Score: 1

      If 90% of a population becomes immune, the chances of the disease spreading within it diminishes accordingly. Eventually, all live carriers die of old age or the disease, and no new carriers are produced, thus eliminating the disease from the population. Heck, even a 55 % successful vaccine could do this, it would just take longer.

      What you're describing is herd immunity, and the required effectiveness of the vaccination effort depends on the specific disease. For smallpox, with a short infectious asymptomatic period and easy transmission, the threshold is around 85%: a vaccine that is less than 85% effective cannot be used to eradicate smallpox. HIV has a very long period (years) when someone can infect others but has no symptoms, so I'd expect the herd immunity threshold to be very high -- possibly 99% or higher.

      --
      "They redundantly repeated themselves over and over again incessantly without end ad infinitum" -- ibid.
    7. Re:10% by DriedClexler · · Score: 1

      Neat, thanks for the explanation!

      --
      Information theory is life. The rest is just the KL divergence.
  11. This is slashdot... by publiclurker · · Score: 1

    What do you think?

    1. Re:This is slashdot... by reeno49 · · Score: 1

      What do you think?

      I think his/her intention was not to think.

      --
      I should have been a girl, with the way I can dance... my moves are amazing!
    2. Re:This is slashdot... by someSnarkyBastard · · Score: 1

      Can't they be both?

  12. Re:Getting an immune response will not help by Anonymous Coward · · Score: 1, Insightful

    I'm certain that eminent molecular biologists who developed the vaccine in question are grateful to you for sharing your valuable insight with the world, because I'm sure that as an Anonymous Coward on Slashdot, you are so much more qualified and knowledgeable than they are about HIV's abilities and vulnerabilities.

  13. awesome by rish87 · · Score: 5, Funny

    I can finally go back to sharing needles. I gotta save money, what with the economy in the gutter.

    1. Re:awesome by sam0737 · · Score: 1

      Just needles? After all HIV is infamous for STD...

    2. Re:awesome by jovius · · Score: 1

      This is Slashdot.

  14. Re:This is bad by Synerg1y · · Score: 1

    Rofl, they still have aids.

    Nice anti-government remark ;)

  15. Re:90% chance that prostitue won't kill you by i+kan+reed · · Score: 1

    If only there were any evidence of that. Lifetime monogamy is not necessarily a healthy relationship. There are lots of reasons for that, not least of which being that people change, and not always positively. Moreover you are pretending the only transmission vector is sex, which is just absurd given how the pathogen actually spreads.

  16. Re:PhiCorp by impaledsunset · · Score: 1

    Meh, I don't care, even an AIDS epidemic can't possibly be worse than Miracle Day.

  17. Natural? by Atzanteol · · Score: 1

    "The MVA-B vaccine draws on the natural capabilities of the human immune system"

    Isn't that how *all* vaccines work?

    --
    "Ignorance more frequently begets confidence than does knowledge"

    - Charles Darwin
    1. Re:Natural? by Delarth799 · · Score: 1

      Most vaccines introduce a dead or severely weakened version of the disease into the body so the immune system can recognize the disease and kill it in the future. This vaccine attacks the virus itself and strips if of the ability to attack the immune system and allows it to do its job. So its not really doing what a normal vaccine would do by introducing a dead HIV virus into the body.

  18. Re:90% chance that prostitue won't kill you by nomel · · Score: 2

    So, you're saying you can have sex with 100 vaccinated prostitutes and only get HIV once...

  19. Re:90% chance that prostitue won't kill you by reeno49 · · Score: 1

    Consider yourself sued!

    We could alternatively settle out of court with a game of Quake 3.

    --
    I should have been a girl, with the way I can dance... my moves are amazing!
  20. Re:90% chance that prostitue won't kill you by Dahamma · · Score: 2, Insightful

    And don't ever get sick enough to need a blood transfusion.

    Oh, and don't ever work in the health industry or volunteer anywhere that you could accidentally come in contact with infected blood.

    Are you trolling or just that naive?

  21. Re:90% chance that prostitue won't kill you by HateBreeder · · Score: 4, Insightful

    Because HIV infected individuals have a large glowing neon sign attached to their foreheads saying "I HAVE HIV!"

    --
    Sigs are for the weak.
  22. Re:90% chance that prostitue won't kill you by Synerg1y · · Score: 1

    Getting raped doesn't imply a healthy relationship at all, the consent is KINDA MISSING (unless thats your thing rofl). Also men get raped all the time, DOC, strange european ladies (she was actually kinda hot), etc...

  23. Re:90% chance that prostitue won't kill you by flaming+error · · Score: 2

    It is not "100% effective" because sexual intercourse is not the only transmission vector.

    It is unrealistic because we have a very strong instinct to reproduce, and that generally involves at least one other person/orangutan whose HIV status we don't really *know* except perhaps a short period immediately after they are tested.

  24. Re:90% chance that prostitue won't kill you by hedwards · · Score: 1

    That's not prevalent enough to be much of an issue. What you're forgetting is that rape only spreads HIV in a subset of cases where one party has HIV already. And HIV would almost certainly have died out years ago if rape was the primary driver of new infections.

  25. first post-HIV-cure realization by Tumbleweed · · Score: 2

    Oh yeah, they never did cure Herpes, did they? :(

    1. Re:first post-HIV-cure realization by vlm · · Score: 2

      Oh yeah, they never did cure Herpes, did they? :(

      Too profitable.

      Imagine the crushing damage to the medical industry if they ever cured the common cold?

      --
      "Science flies us to the moon. Religion flies us into buildings." - Victor Stenger
    2. Re:first post-HIV-cure realization by RenHoek · · Score: 1

      To be honest.. once they've tackled HIV, if they start refocusing on the lesser STD's, I wonder if they'll just fall like a house of cards. I mean HIV is pretty advanced. It shouldn't be too hard to take out the remain ones should it? Or am I being too naive?

    3. Re:first post-HIV-cure realization by Belial6 · · Score: 2

      Which makes me suspicious. The can make a vaccine for the variant of Herpes (Chicken Pox) that has one outbreak, and that is the end of it, but they can't make a vaccine for the variant that has reoccurring outbreaks for the the persons entire life. For that variant, they can only come up with on going treatment to suppress the symptoms.

    4. Re:first post-HIV-cure realization by medv4380 · · Score: 2

      Naive, herpes hides in nerve cells between breakouts. I'm sure if you trained the immune system to hunt it down in those cells their would be other consequences. Your immune system deals with it just fine when it finds it, but killing nerve cells is usually bad. This is also why the 1st outbreak is usually the worst with Herpes since once you're body know what it is it can kill it before it causes too much damage, but depending on the version it still causes damage.

    5. Re:first post-HIV-cure realization by afidel · · Score: 2

      Actually the Herpes virus (varicella zoster) that causes chicken pox does have recurrence in many people, it's what causes shingles. For those people all they can do is help the symptoms as well (though the chicken pox vaccine will now eliminates symptoms for some significant percentage of those so affected). Now that the Valtrex patent has expired (2008) I'm sure there's some incentive to create a vaccine (though getting it used in the general population is going to be difficult, see all the ignorant uproar over the HPV vaccine).

      --
      There are 4 boxes to use in the defense of liberty: soap, ballot, jury, ammo. Use in that order. Starting now.
    6. Re:first post-HIV-cure realization by medv4380 · · Score: 1

      Actually even though you only get Chicken Pox once the virus can reinfect and then it's called Shingles. The Chicken Pox Vacinne does not stop the potential of reinfection resulting in Shingles.

    7. Re:first post-HIV-cure realization by samkass · · Score: 1

      Which makes me suspicious. The can make a vaccine for the variant of Herpes (Chicken Pox) that has one outbreak, and that is the end of it, but they can't make a vaccine for the variant that has reoccurring outbreaks for the the persons entire life. For that variant, they can only come up with on going treatment to suppress the symptoms.

      Think about it... The vaccine works the same way actually getting Chicken Pox works from the immune system's memory's point of view. The fact that you tend to only get chicken pox a few times in your life (if you include shingles) is why there can be so effective a vaccine. The fact that the immune system can't keep some other herpes in check as well is why a vaccine is less effective for those variants.

      --
      E pluribus unum
    8. Re:first post-HIV-cure realization by Time_Ngler · · Score: 1

      There are a lot of drugs for HIV suppression, too. So why wouldn't HIV also be "too profitable" to develop a vaccine for?

    9. Re:first post-HIV-cure realization by Altus · · Score: 1

      There is considerable research into a herpes vaccine, I have been seeing articles about it for the past few years. Given the chicken pox vaccine is, what, 15 years old? I don't think its that surprising that herpes is taking a little bit longer, especially when you consider that it doesn't get nearly the funding that HIV does (or probably even chicken pox, which can kill people who get it late in life)

      --

      "In America, first you get the sugar, then you get the power, then you get the women..." -H. Simpson

    10. Re:first post-HIV-cure realization by Capt.DrumkenBum · · Score: 2

      Poor Africans can not afford HIV suppression drugs.

      --
      If I were God, wouldn't I protect my churches from acts of me?
    11. Re:first post-HIV-cure realization by geekoid · · Score: 1

      You completely misrepresent that link to about.com.
      And there is a vaccine for shingles.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    12. Re:first post-HIV-cure realization by geekoid · · Score: 1

      "Which makes me suspicious"

      Yes, ignorant people are often suspicious of what they don't understand.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    13. Re:first post-HIV-cure realization by geekoid · · Score: 1

      Yes, all those doctors telling you to stay home and rest would be out all that money there not getting anyways.

      Idiot.

      If there was a conspiracy, it would be from Vitamin C huxsters... but there isn't.

      The common cold is
      A) Hard
      B) Not very critical.

      That said, if a company came up with a 'cure' they would make billion of dollars in a quarter, and the C*O would get hundreds of million in bonuses. Or maybe they're nice guys and they would sit on the cure so some other company can make billions.

      Finally, a cure wouldn't make the cold go away. IT would be a vaccine that would get administered to each generation.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    14. Re:first post-HIV-cure realization by geekoid · · Score: 1

      Yes, silly of them putting the money into finding a cure for a disease that kills people instead of one that makes people's crotch itch.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    15. Re:first post-HIV-cure realization by Tumbleweed · · Score: 2

      Yes, silly of them putting the money into finding a cure for a disease that kills people instead of one that makes people's crotch itch.

      Your righteous indignation would be more impressive if it had anything to do with what I said. I never said nor did I imply anything of the sort. Outside of your head, that is.

    16. Re:first post-HIV-cure realization by MightyMartian · · Score: 1

      I don't think shingles is from reinfection per se, but rather from incomplete infection which allows some of the virus to hide out for long periods of time before new symptoms show up.

      --
      The world's burning. Moped Jesus spotted on I50. Details at 11.
    17. Re:first post-HIV-cure realization by rve · · Score: 1

      Oh yeah, they never did cure Herpes, did they? :(

      Too profitable.

      Imagine the crushing damage to the medical industry if they ever cured the common cold?

      This level of paranoia is over the top. The pharmaceutical industry isn't holding back a cure because treatment of symptoms is too profitable. It just happens to be so difficult to develop a cure for a viral infection, that as far as I'm aware, not a single one exists for any virus. All we have (as far as I'm aware) are vaccines, and for some viruses inhibitors that suppress, but do not cure a viral infection.

      By the way, how is the medical industry making any money off the common cold right now? Now if they found a cure, then they'd start making billions. Wouldn't you buy a cure if you had a cold? I know I would stockpile vast quantities of the stuff, if there was a cure. Would I pay $100 to cure a cold? Definitely! $250? Probably. $1000? Depends. If I had my 2 weeks of vacation or some special occasion coming up, I'd consider it.

    18. Re:first post-HIV-cure realization by rakaur · · Score: 1

      No one actually knows the exact mechanism of herpes zoster. We know it requires an initial infection with varicella zoster and that it usually takes years to resurface. It does not have anything to do with an "incomplete infection" or a "reinfection." The mechanism is not understood.

    19. Re:first post-HIV-cure realization by afidel · · Score: 1

      Dude there was uproar about the HPV vaccine before it was even available. All the idiots saying "my 12 year old isn't going to turn into a slut so there's no need for her to get the vaccine". The reality of the situation is they all *should* have it as it's an easy way to reduce their chances of getting a life threating illness, we require all children to get the chickenpox vaccine and the incidence of chickenpox being life threating is miniscule.

      --
      There are 4 boxes to use in the defense of liberty: soap, ballot, jury, ammo. Use in that order. Starting now.
    20. Re:first post-HIV-cure realization by Belial6 · · Score: 1

      Are you seriously claiming that suspicion is a sign of ignorance? That has to be the stupidest thing I have heard all day.

  26. Go Educate yourself by Radtastic · · Score: 1

    You are woefully uneducated. I suggest you use your google-fu on other ways HIV is transmitted.

    Yes, sex with an infected partner. And sharing of needles, blood transfusions, and babies born from infected mothers, to name a few.

    --
    You stereotypers are all the same...
  27. Re:90% chance that prostitue won't kill you by Radres · · Score: 1

    90% * 90% = 81%. This is the chance that two events with 90% probability will occur at the same time independent of each other. I think what you're trying to say is 90% + (90% * 10%) = 99%.

  28. Free love baby! Groovy! by RenHoek · · Score: 1

    I wonder if a vaccine against AIDS will result in a sexual revolution as happened in the '60s with the advent of birth control pills.

    And yes, I do know there's more then one STD out there, but that didn't stop them in the 60's either.

    1. Re:Free love baby! Groovy! by jellomizer · · Score: 1

      Probably not.
      Most people realized that people do want relationships more then just blind sex for most people.
      AIDS didn't put a stop to it. It was on its way out before AIDS but AIDS did give the opponents extra reasons.

       

      --
      If something is so important that you feel the need to post it on the internet... It probably isn't that important.
    2. Re:Free love baby! Groovy! by pixelpusher220 · · Score: 2

      I'm sure there will be some affect on behavior.

      What I believe will *really* launch the next sexual bonanza is a simple 5 minute 'blood test on a chip' for the various STDs. Don't have to cure it, just know if the person you're going to humpty-hump with is likely clean.

      And that really can't be that far off in the future me thinks. Testing for the existence of a disease is infinitely simpler than curing it.

      --
      People in cars cause accidents....accidents in cars cause people :-D
    3. Re:Free love baby! Groovy! by pixelpusher220 · · Score: 1

      Most people realized that people do want relationships more then just blind sex

      if by 'most people' you mean female yes. Most men still want random gratuitous sex as often as they can get it for the better part of their teens and 20s. It's genetic mostly but also nicely reinforced by societal stereotypes.

      --
      People in cars cause accidents....accidents in cars cause people :-D
    4. Re:Free love baby! Groovy! by Altus · · Score: 1

      HA HA HA!

      good joke man.

      --

      "In America, first you get the sugar, then you get the power, then you get the women..." -H. Simpson

    5. Re:Free love baby! Groovy! by Belial6 · · Score: 1

      False dichotomy.

  29. Science 1000000001, god 0 by hyades1 · · Score: 3, Funny

    Looks like the big, homophobic Guy in the Sky takes another one in the 'nads from our friends in the medical research community.

    I wonder what Pat Robinson's got to say about this. He's been remarkably quiet since all those tornadoes ripped through the Bible Belt, sucking up true believers like a vaccuum cleaner on meth.

    --
    I've calculated my velocity with such exquisite precision that I have no idea where I am.
    1. Re:Science 1000000001, god 0 by anagama · · Score: 4, Insightful

      Not just homophobic, crustaceaphobic as well.

      --
      What changed under Obama? Nothing Good
    2. Re:Science 1000000001, god 0 by Anonymous Coward · · Score: 1

      So medical breakthroughs are now a great big "fuck you" to organized religion.

      I think someone needs to grow up.

    3. Re:Science 1000000001, god 0 by sdguero · · Score: 1

      Nice. :)

    4. Re:Science 1000000001, god 0 by hitmark · · Score: 1

      i actually lol-ed...

      --
      comment first, facts later. http://chem.tufts.edu/AnswersInScience/RelativityofWrong.htm
    5. Re:Science 1000000001, god 0 by kevinNCSU · · Score: 4, Insightful

      Wow, you're giddy about fellow human beings dying because they have different culture and beliefs than you. Is this really the "enlightened" and "evolved" alternative to religion you wish to present?

    6. Re:Science 1000000001, god 0 by font420 · · Score: 1

      Glad someone said it.

    7. Re:Science 1000000001, god 0 by Anonymous Coward · · Score: 2, Insightful

      Or, how about it's a parody of supposedly loving Christians who take joy in the fact people died in tsunamis, and wished it on the people of Dover Pennsylvania; or loving Christians who has no second thought about sending death threats.

    8. Re:Science 1000000001, god 0 by Paladeen · · Score: 1

      Get a sense of humour, fer God's sake. If He does exist, he must be the ultimate joker. I have a feeling he'd like our OP's tongue-in-cheek flippancy.

    9. Re:Science 1000000001, god 0 by im_thatoneguy · · Score: 1

      So medical breakthroughs are now a great big "fuck you" to organized religion.

      Yes. Because organized religion says that God is either unable or unwilling to cure us of diseases--and that Satan afflicts them upon the human race as the result of sin.

      If we wipe out infectious diseases and cancers then we prove that your average med student is both more capable and caring than the divine.

      Why worship a guy who will give you the finger when you get cancer and other ailments that a doctor can easily treat?

    10. Re:Science 1000000001, god 0 by Pharmboy · · Score: 1

      Thank you, if for no other reason than the link to make your own bogus church signs that I found on that page. Has already come in handy.

      --
      Tequila: It's not just for breakfast anymore!
    11. Re:Science 1000000001, god 0 by Anonymous Coward · · Score: 1

      The Bible Belt? There's very few true believers. The founder of the Roman Catholic church Constantine was a sun worshipper. He made a so called conversion to christianity and then after through persectution and the inquistions of the roman catholic church most of the protestants converted to sunday worship to avoid persecution. Now we have the world in mass disobeying one of God's Ten Commandments under a bunch of false excuses as for why they worship on sunday. Such as being saved by grace through faith. Paul says "shall we continue to sin that grace may abound? God forbid." And false interpretations of other New Testament scriptures, and then claim see, this is why we keep sunday. But they are wrong.

      “Sunday is a Catholic institution, and its claims to observance can be defended only on Catholic principles...From the beginning to the end of Scripture there is not a single passage that warrants the transfer of the weekly public worship from the last day of the week to the first.” The Catholic Press, Sydney, Australia, August, 1900.

      On 7 March 321, Constantine I decreed that Sunday (dies Solis) will be observed as the Roman day of rest [CJ3.12.2]: On the venerable day of the Sun let the magistrates and people residing in cities rest, and let all workshops be closed...

    12. Re:Science 1000000001, god 0 by Hognoxious · · Score: 1

      I wonder what Pat Robinson's got to say about this.

      Same as me: "Shit, I'd have bought some Apple stock if I'd have known earlier!"

      --
      Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    13. Re:Science 1000000001, god 0 by JonySuede · · Score: 1

      Saying were is your god now, he is clearly existent as he has not helped you devote worshipper, is not the same as getting giddy.

      And I would add that irrational beliefs should be mocked. They had the irrational belief that an anthropomorphic god would protect them, it clearly has not. Sure, theologians came with plenty of rational sounding explanations for this, but they do not hold if you do use n order predicate calculus on them.(Lawyers and politicians should be mock to for pretty much the same reason).

      Someone might ask why use mockery, as mockery sounds mean and unenlightened ? You use mockery to fight irrational belief as by definition irrational believer cannot be argued with. However mockery works the emotive part of the brain were reason cannot reach.... That is why believers should be mocked and not argued with.

      Someone else might also ask : why this instead of nothing? There must be a god since we exist. Any anthropomorphic god with a will of some-kind still can't answer the precedent question, it just add an indirection level and you end up with the following question: why god instead of nothing.

      And I would like to conclude that I love it (even if someone mock me) when someone highlight an irrational belief that I hold as it enables me to be more rational.

      --
      Jehovah be praised, Oracle was not selected
    14. Re:Science 1000000001, god 0 by JonySuede · · Score: 1

      s/were/where

      --
      Jehovah be praised, Oracle was not selected
    15. Re:Science 1000000001, god 0 by anagama · · Score: 1

      Obviously. That's what makes it funny.

      --
      What changed under Obama? Nothing Good
    16. Re:Science 1000000001, god 0 by randyleepublic · · Score: 1

      Whoosh city much?

      --
      Social Credit would solve everything...
    17. Re:Science 1000000001, god 0 by hyades1 · · Score: 1

      Thanks for the honkin' big laugh I got out of that.

      --
      I've calculated my velocity with such exquisite precision that I have no idea where I am.
    18. Re:Science 1000000001, god 0 by hyades1 · · Score: 1

      So speaks the doofus logged in as "Anonymous Coward". By the way, that loud roaring sound you heard was the point blasting its way over your head.

      --
      I've calculated my velocity with such exquisite precision that I have no idea where I am.
  30. Gay Related Immune Defficiency by Anonymous Coward · · Score: 1
    1. Re:Gay Related Immune Defficiency by betterunixthanunix · · Score: 1

      The sad thing is the number of people who still believe that HIV/AIDS is a gay man's disease. While female-to-male transmission is less prevalent, it has never been unheard of, and as that very article points out Africa is one of the hardest hit regions of the entire world. It was only referred to as GRID early on because the spread began in homosexual communities in major cities.

      --
      Palm trees and 8
  31. Re:90% chance that prostitue won't kill you by S.O.B. · · Score: 2

    I don't understand why the concept is so difficult. There is a 100% effective way to prevent catching HIV. Don't have sex with someone who has it! Why is that so unrealistic?

    Perhaps it's unrealistic because it's not true. For example,

    Contaminated haemophilia blood products
    Blood transfusions
    Transmission from mother to child
    Needlestick injuries to health workers

    It's also theoretically possible to get it from tattoos and piercings although no known cases have been documented.

    --
    Some of what I say is fact, some is conjecture, the rest I'm just blowing out my ass...you guess.
  32. Re:90% chance that prostitue won't kill you by Anon-Admin · · Score: 1

    Not taking a side but you did ask for numbers. CDC Published numbers for 2009

    Estimated Number of Diagnoses of HIV Infection, 2009

    Male-to-male sexual contact 23,846
    Injection drug use 3,932
    Male-to-male sexual contact and injection drug use 1,131
    Heterosexual contact 12,860
    Other 76

    There are the 2009 numbers.

    BTW, in a Healthy relationship Men and Women cheat and do not tell there partner! The percentages of cheaters among men and women were 52% and 66% respectively.

  33. Re:90% chance that prostitue won't kill you by ShavedOrangutan · · Score: 1

    Thank you for researching that.

    I realize that nobody ever decides to catch it, but 99.8% of those cases COULD have been avoided.

    --
    Godaddy is a scam and a ripoff.
  34. Southpark Cure by milbournosphere · · Score: 1

    I guess they finally managed to cram the required shit-ton of money into a single syringe.

  35. Re:90% chance that prostitue won't kill you by ewieling · · Score: 3, Insightful

    Having only "safer sex", sex with only one partner, and abstinence goes against our nature. Our entire biology is geared to reproducing and spreading our genes as widely as possible. You will never get 100% of people to have protected sex 100% of the time. You will never get 100% of people in monogamous relationships to not cheat. The best we can do is get the largest percentage of people we can to do things which reduce their chances of contracting HIV. Rather than live in the fantasy world where nobody makes bad decisions, why not live the real world? I don't understand why the concept is so difficult.

    --
    I really shouldn't have used someone else's email address for this account.
  36. I was born by Janvitos · · Score: 1

    On 1983, the year the HIV was "discovered". I'm glad I might actually live to see it extinct.

  37. Re:90% chance that prostitue won't kill you by bky1701 · · Score: 1

    I don't know about that, but I have a sure-fire way to not die from HIV. You see, it is simple. If you find you have contracted HIV, jump off the nearest bridge. You will no longer need to worry about HIV! Of course, this process only has about a 99% success rate, so you might need to repeat it a few times to ensure you are cured of HIV.

    Yes, that was sarcasm. I know it's hard to tell with some of the idiots out there on this topic.

  38. Re:90% chance that prostitue won't kill you by aristotle-dude · · Score: 1

    Healthy relationships would kill HIV 100%, not 90.

    Have you heard of the saying about not throwing "pearls" before swine? Worldly people don't like to think of the consequences of their actions or think of relationships in terms of emotional entanglements.

    I agree with you 100% but many people just don't seem to get that STDs exist as a deterrent for certain types of behaviours.

    --
    Jesus was a compassionate social conservative who called individuals to sin no more.
  39. Re:90% chance that prostitue won't kill you by Anon-Admin · · Score: 2

    I think your percentage is off. 30%+ are Heterosexual contact. You are assuming that all of that is from unhealthy relationships where in reality an unknown percentage is contact within a healthy relationship.

    Remember, in a normal and healthy relationship men and women will cheat 52% and 66% respectively.

  40. Re:90% chance that prostitue won't kill you by bky1701 · · Score: 1

    Yes, just never have sex. Uh huh. How about you head back to the pulpit, where people feel obliged to listen to you (and then ignore what you said afterwards).

  41. Re:How do they test?? by tungstencoil · · Score: 3, Informative
    Historically take a sample set of people considered to be at-risk for HIV, give them safer-sex counseling, and then track them against a control for infection rates. This study was different (hate to say RTFA, but it does describe it):

    Development of MVA-B is based on the insertion of four HIV genes in a previously used vaccine (MVA) for smallpox. When injected with the vaccine, a healthy immune system can react against the MVA, whilst the HIV genes are incapable of self-replicating. This guarantees a safe clinical trial for HIV free volunteers. Furthermore by trialing the vaccine on healthy patients, the immune system can learn how to detect and combat the HIV virus components. "It is like showing a picture of the HIV so that it is able to recognize it if it sees it again in the future", says Esteban.

  42. Re:90% chance that prostitue won't kill you by pixelpusher220 · · Score: 1

    Even throwing out the ridiculous concept that the 'male-to-male' doesn't include long term stable relationships, the heterosexual contact certainly contains a significant number of long term stable relationships.

    Since people *do* cheat, you can't prevent what you don't know about, since cheating is quite frequently...secret. So all the long term stable partners of 'cheaters' who caught HIV couldn't do anything to prevent infection.

    Injection drug use - insulin is a legal form of this and certainly has some placement in the numbers. So unless you want to live in the fantasy world of Leave it to Beaver, no, 99.8% weren't preventable.

    --
    People in cars cause accidents....accidents in cars cause people :-D
  43. Re:How do they test?? by pixelpusher220 · · Score: 2

    Yes. Oh and your mom will be home a little late tonight...

    --
    People in cars cause accidents....accidents in cars cause people :-D
  44. Immunological response? by Guppy · · Score: 4, Insightful

    HIV vaccine in which 90% of volunteers developed an immunological response against the virus.

    This is an absolutely meaningless measure; seroconversion against HIV is easy to achieve, and typically worthless. The elicited antibodies end up being targeted to highly variable regions, and have little long-term neutralizing power.

    Although a handful of unusual broadly neutralizing antibodies have been found among "elite controllers", it is extremely rare for typical individuals to generate them. There's been some speculation it might be possible to create an effective vaccine by directing the response away from decoy regions, and towards the handful of areas targeted by such elite antibodies. Thus far, nobody has managed such a feat, unfortunately.

    1. Re:Immunological response? by Guppy · · Score: 1

      However generating a long lasting response against future attacks truly renders the vaccine effective.

      A longer-lasting non-protective response is still non-protective. As someone who has previously participated in HIV vaccine research, I still see nothing in this vaccine to suggest it will overcome the very large obstacles that have caused so many previous ones to fail.

    2. Re:Immunological response? by kanto · · Score: 1

      Wow I understood almost none of that - I'm assuming I should mod this up...

      You must be new here

  45. Re:90% chance that prostitue won't kill you by ShavedOrangutan · · Score: 1

    I never said anything about sexual preference having anything to do with whether a relationship is safe or not. You're assuming that because I said "Abstinence is safest" that I must be some bible thumping homophobe.

    How can insulin have anything to do with HIV? I know lots of diabetics and none of them are sharing needles. Spreading HIV through drug use should be 100% preventable. I thought drugs were expensive? Why share a cheap IV needle? Most people wouldn't share a toothbrush!

    --
    Godaddy is a scam and a ripoff.
  46. Re:90% chance that prostitue won't kill you by jdpars · · Score: 2

    I think this may have been a reference to the now-infamous "your an idiot" response. Not sure though. 50% possibility it's an actual idiot, 50% possibility of a reference.

  47. popU-LAytion conTROLL by citylivin · · Score: 1

    Why, are you a member of the world health organization?

    Uncivilization!

    --
    As a potential lottery winner, I totally support tax cuts for the wealthy
  48. Re:90% chance that prostitue won't kill you by Duradin · · Score: 1

    If you know how monogamous hetero relationships can prevent transmission from non-sexual activities could you pass that along to the proper authorities?

  49. Immune response immunity by tpjunkie · · Score: 1

    Just because an immune response in the form of circulating antibodies from B cells is seen does not mean infection and replication will not occur when a person is exposed to HIV; most people with HIV have high levels of HIV antibodies circulating in their blood, but the rate at which the virus mutates, as well as the fact that the epitopes the body naturally develops immune responses to are "hidden" by the way in which the viral capsular proteins are folded means that the antibodies do little if anything to halt infection. Furthermore, the CD4+ T cells which initiate a more effective immune response are one of the two types of cells the virus infects (the others being macrophages). At this point, the article gives no further details or useful specifics. If they had said they had generated a cytotoxic CD8+ cell response, or perhaps an immune response against one of the conserved regions of the gp120 or gp41 viral receptors, then I'd be interested. Till then, I am going to be quite skeptical about this until they have some efficacy data. (I am a medical student with an MS in biomedical science)

  50. Re:90% chance that prostitue won't kill you by jimbolauski · · Score: 5, Informative

    In the US there has been one known HIV transmission through blood transfusion in the last 8 years the chances of getting HIV from a blood transfusion are 1 in 1,500,000. 1 in 400 people who get stuck with a needle or cut with a sharp from a person with HIV contract the virus there have been 57 cases of health care workers getting HIV at work there are 12,000,000 health care workers. Getting HIV is not that easy mostly bad decisions have to be made to get HIV. The chances that you get HIV from a source besides sex and sharing needles is too small to consider 0.000002% you have a better chance of dieing from constipation.

    --
    Knowledge = Power
    P= W/t
    t=Money
    Money = Work/Knowledge so the less you know the more you make
  51. Re:Did they intentionally infect 10% of the people by Jarik+C-Bol · · Score: 1

    you give them the vaccine, wait a while, draw blood, expose that blood to the disease, then watch under a scope and see what happens.

    --
    I've decided to Diversify my Holdings. I've divided my cash between my left and right pockets, instead of all in one.
  52. I think people forget this by Sycraft-fu · · Score: 4, Insightful

    Vaccines against viruses work because they train the immune system to attack the virus. They introduce something that gets it going. Can be a dead virus, can be a live but weakened virus, but whatever the case it trips off the immune system which produces a tailor made response. The immune system can then use that to kill any future invasions from that virus.

    This is the same thing that happens when someone gets sick. However in that case, the live (in so far as a virus is alive) and fully active so it overwhelms the body for awhile until the body can formulate the response and fight back. All the vaccine does is make that process easier and safer.

    The flip side of that is if it is the sort of thing the immune system fights off, but then it comes back, well a vaccine won't work, at least not a vaccine in the classical sense. If the immune system can't develop an effective repeating method to kill the virus, then a vaccine won't help.

    Really this shit is not a big medical conspiracy, it is just how things work. What's more, the more things we cure, the harder the things are that remain. We fixed the things that were easy to fix long ago. We are getting to the hard shit now.

  53. Interesting HIV transmission rate stats by GodfatherofSoul · · Score: 1

    I was on a blog once where a guy posted that there's only about a 1/1000 chance of contracting it from an affected person. He then got flamed into dust. I looked up his numbers and it's actually true! During normal sexual intercourse, the rates are 1/1000 male (infected) to female and 1/2000 female (infected) to male. With rates that low, I don't even think "sexually transmitted" is the right word. You probably have to have an open wound, scratch, or open sore from another STD to transmit the virus.

    Now, when you start getting kinkier (e.g. anal) the rates start going up. I can't recall the numbers for these, but I think they were around the percentile range (give or take a few factors of 2). I think because the skin in your nether regions is much thinner and porous. This is why the gay community has been so devastated by AIDS. Additionally, the rate of HIV in gay males is 1/5 with half that number not even being aware that they're infected :(

    --
    I swear to God...I swear to God! That is NOT how you treat your human!
    1. Re:Interesting HIV transmission rate stats by geekoid · · Score: 2

      It's 1/500, and the more it's studied the worse it gets. well, it's not getting worse, the number is just getting more accurate.

      As an example, in 1988, they where saying 1 in 5 billion chance if you used a condom

      http://www.nytimes.com/1988/04/22/us/researchers-list-odds-of-getting-aids-in-heterosexual-intercourse.html?pagewanted=all&src=pm

      while other STDs have anywhere from a 10% to 50% transmission rate, AIDS is still a sexual transmitted disease.
      "You probably have to have an open wound, scratch, or open sore from another STD to transmit the virus."
      Also, and even if it was true, sexual transmitted would be the correct term.

      while 1/500 doesn't sound bad, bear in mind tit's 1/500 for one(1) encounter. Most sexual active people have more then one encounter. When I was sexual active, I would have 5-15 partners a month.

      That was in the late 70's to about '84. In '84 I found out about AIDS and pretty much stopped being sexual active with anyone I hadn't dated and got to know. Seriously, STD went from 'It may be painful to cure you..but probably not' to 'You will die'.
      Because it's important to this conversation, they where heterosexual encounters.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    2. Re:Interesting HIV transmission rate stats by GodfatherofSoul · · Score: 2

      Thanks for that correction. "Per encounter" really does change the nature of the risk.

      --
      I swear to God...I swear to God! That is NOT how you treat your human!
    3. Re:Interesting HIV transmission rate stats by im_thatoneguy · · Score: 1

      Most sexual active people have more then one encounter. When I was sexual active, I would have 5-15 partners a month.

      http://www.youtube.com/watch?v=YwNVE37BGVE

  54. Re:90% chance that prostitue won't kill you by X0563511 · · Score: 1, Offtopic

    This isn't /b/, so your use of 'fag' makes you an intolerant asshole of a bigot.

    Kindly go dive into a fire.

    --
    For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
  55. Re:90% chance that prostitue won't kill you by X0563511 · · Score: 1

    DOC?

    --
    For large sets, this will be our guide even unto death, for the LORD will work for each type of data it is applied to...
  56. Re:90% chance that prostitue won't kill you by CyprusBlue113 · · Score: 1

    Tell that to Africa

    --
    a handful of selfish greedy people are no match for millions of selfish, greedy people -u4ya
  57. Re:Phase I Trial by zebslash · · Score: 1

    True, but this also depends on which class of medicine. There there are also some efficacy data collected with vaccines.

  58. Science by geekoid · · Score: 1

    it delivers the goods... bitch.

    For those playing the home game:
    Science: million+
    Alternative meds: 0

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    1. Re:Science by Ocker3 · · Score: 1

      Only because Science keeps stealing players from the Alt team if they can pass the entrance tests. Some Alt meds don't really do much or are harmful, others simply haven't been tested yet, either because noone's taken the time, or noone can figure out how to make money selling them on a large scale. A lot of modern medications were folk remedies until someone ran some proper tests and realised that there actually Was something potent in that funny-tasting tea.

    2. Re:Science by bill_mcgonigle · · Score: 1


      Science: million+
      Alternative meds: 0

      You forgot about all the people who have been praying for a cure!

      (invoking Poe's Law now)

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
  59. Re:90% chance that prostitue won't kill you by robot256 · · Score: 1

    Based on your argument, anyone who contracts HIV should be put in solitary confinement so they cannot transmit it to others, same as murderers. You can only get so far in suppressing animal instincts while ignoring the consequences of the ones that inevitably slip up. Besides, I'd much rather have a society where people go around fucking each other than beating each other to death, which is why the prisons are full of violent offenders instead of adulterers. (Though IIRC, there was an article a while back on how promiscuity vs. monogamy was actually a genetic spectrum and people naturally wind up all over this spectrum. It's not like *everyone* is programmed to be irresponsible.)

    And you also ignore the fact that the site of the real HIV epidemic is Africa, where many cultures almost *expect* everyone to have multiple sexual partners. There are efforts to change the culture, but culture changes VERY slowly and in the mean time people are dying. A vaccine like this would be of immeasurable value to them.

  60. Re:90% chance that prostitue won't kill you by CrazyDuke · · Score: 1

    I frequently find that people that people that push for extremely limited sexual contact usually only take that advice seriously when it involves other people contributing other genes to the gene pool, their teenage daughter. (That changes BTW. Usually in the twenties and later, the heat is on for grandkids.)

    --
    Any sufficiently advanced influence is indistinguishable from control.
  61. Re:90% chance that prostitue won't kill you by MightyMartian · · Score: 1

    Yes, because the only possible vector for HIV infection is through sexual intercourse

    --
    The world's burning. Moped Jesus spotted on I50. Details at 11.
  62. Re:90% chance that prostitue won't kill you by morari · · Score: 1

    I wish I could settle [i]everything[/i] out of court with a match of Quake III Arena. My 1337 skills would practically position me above the law! :)

    --
    "He who can destroy a thing, controls a thing." --Paul Atreides, Dune
  63. Re:90% chance that prostitue won't kill you by duguk · · Score: 2, Funny

    In the US there has been one known HIV transmission through blood transfusion in the last 8 years the chances of getting HIV from a blood transfusion are 1 in 1,500,000. 1 in 400 people who get stuck with a needle or cut with a sharp from a person with HIV contract the virus there have been 57 cases of health care workers getting HIV at work there are 12,000,000 health care workers. Getting HIV is not that easy mostly bad decisions have to be made to get HIV. The chances that you get HIV from a source besides sex and sharing needles is too small to consider 0.000002% you have a better chance of dieing from constipation.

    So, still not 100% then?

  64. Re:90% chance that prostitue won't kill you by duguk · · Score: 1

    In no way does gaysex spread your genes as widely as possible. It may spread your jeans, though.

    Your face when you realise you're the only person who's brought up 'gay sex'...

  65. Re:90% chance that prostitue won't kill you by electron+sponge · · Score: 1

    Department of Corrections?

  66. Re:90% chance that prostitue won't kill you by Falconhell · · Score: 1

    If it quacks like a duck....

  67. Re:90% chance that prostitue won't kill you by Dahamma · · Score: 2, Informative

    What the hell does any of this have to do with the US? The vaccine from the original article wasn't even developed in the US. HIV isn't an epidemic "in the US", but that doesn't mean it's not worth pursuing a vaccine.

    If you want to quote statistics - in Africa the estimate is 250-500 people a DAY contract HIV from unsafe (either contaminated blood or equipment) transfusions. Some 3rd world countries in Asia are almost as bad. And since there is such a higher rate of HIV and such poor health care conditions, it's much more dangerous for the health care workers as well.

    But I guess same pseudo-moralistic bullshit attitude that would pretend to argue HIV is not a world epidemic and is only contracted by all of those fornicators and addicts probably doesn't give a shit about anyone outside of their tiny little world, anyway.

  68. Re:90% chance that prostitue won't kill you by Synerg1y · · Score: 1

    AH, but I've moved on to battlefield 3 and SC2 (long timer) nowadays. Quake 3 ftw though :) I remember!

  69. Re:90% chance that prostitue won't kill you by Duradin · · Score: 1

    He agreed 100% that a healthy relationship could prevent 100% of HIV so I was really curious how it takes care of the non-sexual transmission vectors.

  70. Re:90% chance that prostitue won't kill you by Ocker3 · · Score: 1

    Exactly, you Still don't want to be one of those 57 people. It would be a Huge boost to peace of mind for healthcare workers to have this on hand, they could have a blood test for active T-cells of the right type, and be confident that any HIV infection would get stopped. I'd be interested to know if being vaccinated pre-infection would mean you'd never have to worry about passing it on to anyone though, that would still make sex a problem, even if you weren't going to die from AIDS.

  71. Re:90% chance that prostitue won't kill you by im_thatoneguy · · Score: 1

    You missed the obvious one:

    Partners could lie. Sure you're in a "healthy" relationship...

  72. Re:90% chance that prostitue won't kill you by MightyYar · · Score: 1

    People without vaginas often have a hard time remembering the whole rape thing, but women do get raped.

    Aside from that, there is always the good ol' cheating spouse. You can be a Good Christian(tm) and still get AIDS from your fallen-from-grace spouse.

    --
    W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  73. Re:90% chance that prostitue won't kill you by Dahamma · · Score: 1

    Well, you are clearly a troll, too, but I didn't even reply to you, jeez.

  74. Re:90% chance that prostitue won't kill you by Surt · · Score: 1

    Because over 75% of people are surprised to learn that their monogamous sex partner made a different life choice.

    --
    "Who is the Journal of Quantum Physics going to believe?" --Stephen Hawking
  75. Re:90% chance that prostitue won't kill you by moortak · · Score: 1

    Yet you can be in a lovely monogamous screened relationship and your partner could choose not to be. Life throws curveballs sometimes.

    --
    Xavier Rabourdin for president 2012
  76. Re:90% chance that prostitue won't kill you by Anonymous Coward · · Score: 1

    In the US there has been one known HIV transmission through blood transfusion in the last 8 years the chances of getting HIV from a blood transfusion are 1 in 1,500,000.

    That should be two sentences.

    1 in 400 people who get stuck with a needle or cut with a sharp from a person with HIV contract the virus there have been 57 cases of health care workers getting HIV at work there are 12,000,000 health care workers.

    So should that.

    The chances that you get HIV from a source besides sex and sharing needles is too small to consider 0.000002% you have a better chance of dieing from constipation.

    And that.

    Fuckpot.

  77. Phase 1 is about safety, not effectiveness by fropenn · · Score: 1

    How could a phase 1 trial (http://en.wikipedia.org/wiki/Clinical_trial#Phase_I) show 90% effectiveness? Phase 1 trials are about the safety of the drug, not its effectiveness.

    All that phase 1 trials attempt to show is that the drug is not deadly to healthy people and what dosages might be useful. The long-term effectiveness is still to be proven.

    1. Re:Phase 1 is about safety, not effectiveness by Guppy · · Score: 1

      How could a phase 1 trial (http://en.wikipedia.org/wiki/Clinical_trial#Phase_I) show 90% effectiveness? Phase 1 trials are about the safety of the drug, not its effectiveness.

      They mean 90% vs. a "biomarker" -- a measurable physical change used as a benchmark. In this case, production of anti-HIV antibodies.

      I am not expecting anything impressive from actual in-vivo protection; your typical humoral immune response to HIV (like the kind achieved by this vaccine) is not protective. This is an example of an over-hyped press release.

  78. eugenics by KingAlanI · · Score: 1

    I'm inclined to see the point of implementing eugenics in a way that doesn't just amount to racist BS.

    --
    I listen to both RIAA and non-RIAA stuff if I like the music, tangential business/politics nonwithstanding.
    1. Re:eugenics by tehcyder · · Score: 1

      I'm inclined to see the point of implementing eugenics in a way that doesn't just amount to racist BS.

      At what point do you say that everyone who is short sighted, genetically slightly obese, mentally or physically lazy, somewhere on the autistic spectrum, prone to mild depression, anti-social or just plain ugly should be sterilized?

      --
      To have a right to do a thing is not at all the same as to be right in doing it
  79. Re:90% chance that prostitue won't kill you by IgnitusBoyone · · Score: 1

    AIDS is a much bigger problem for underdeveloped countries. Look at the rates in Africa compared to the US and like it or not lowering the transmission rates through proper education drastically reduces the transmission rates through transfusions and other methods. No reason not to research a vaccine and a cure, but when you compare AIDS to something like Malaria or Small Pocks things that are passed through the air or by insects that are virtually impossible to avoid I don't find it so hard to understand why a person would rather donate to other causes.

    Forced and accidental transmission are a problem with any STD, but really want to lower the incident rate which will require a combination of treatments, vaccines and preventive treatment. Weather you want to admit it or not for all STDs this involves both protective measures during and before engaging in sex and saying its not in our nature isn't really the answer.

    --
    Momento Mori
  80. Re:90% chance that prostitue won't kill you by 2fuf · · Score: 1

    > Don't have sex with someone who has it!

    Hmmm, so tell me, how do I control with 100% certainty that my wife never strays and never gets infected?

  81. Re:90% chance that prostitue won't kill you by Artifakt · · Score: 1

    Diabetic needle reuse and sharing is seen almost exclusively in diabetics who are homeless or otherwise at severely low incomes, but it is documented. People who are unable to afford all the oral meds also used, or who have trouble getting the required prescriptions for injectors refilled regularly, do sometimes reuse needles, and even borrow from each other. Needles are controlled by prescription since they are also sought by illegal drug users, meaning diabetics without good access to doctors can run short. In other cases, not being able to afford the oral medications means the diabetic uses needles faster than their doctor thought they might and runs short. It's not that they are as uncaring about the risks as for typical heroin users or similar, but even with some risk awareness, sometimes it's the only option left.

    --
    Who is John Cabal?
  82. Re:90% chance that prostitue won't kill you by werepants · · Score: 2

    What he's trying to say is 10% chance of getting HIV * 10% chance of hooker having HIV = 1% chance of getting it, or 99% chance of not getting it.

  83. Re:90% chance that prostitue won't kill you by Dahamma · · Score: 1

    And those statistics are only for the US, which is a first world country with a modern health care system that provides ready access to retrovirals, thorough testing, and sterile equipment. HIV vaccines aren't about the US.

    There are an estimated 1M cases of HIV in the US, while Sub-Saharan Africa is estimated at well over 30M, with thousands of new cases daily. The WHO estimates 200-400 of those a day come from blood transfusions, so the "1 person in 8 years in the US" is pretty narrow minded...

  84. Re:90% chance that prostitue won't kill you by drsmithy · · Score: 2, Insightful

    Hmmm, so tell me, how do I control with 100% certainty that my wife never strays and never gets infected?

    Make sure her leash doesn't reach to the doorway and install a good security system, of course.

  85. Re:90% chance that prostitue won't kill you by LingNoi · · Score: 1

    because humans lie, don't know they have it then spread it to others that don't know they have it. They rape women and infect them and babies are born with AIDs as well.

  86. Re:90% chance that prostitue won't kill you by ShavedOrangutan · · Score: 1

    I challenge you to find anything in any of my posts that indicate my religious beliefs. Advocating keeping your dick in your pants outside of a monogamous relationship is just common sense and proof that we've evolved beyond monkeys.

    Or maybe we haven't.

    --
    Godaddy is a scam and a ripoff.
  87. Re:90% chance that prostitue won't kill you by manwargi · · Score: 2

    I know! How come these people don't use their powers of omniscience to avoid all the infected people they meet?? And those nurses assigned to HIV patients are such dirty whoring sluts, too.

  88. Re:90% chance that prostitue won't kill you by tragedy · · Score: 2

    Synerg1y wrote:

    Healthy relationships would kill HIV 100%, not 90.

    Clearly you've never heard of rape. While it doesn't fall under the category of healthy relationships, it can still affect people who would otherwise only engage in healthy relationships. For that matter, a person might believe themselves to be in a healthy relationship and be deceived. The arrogant presumption implicit in your post that HIV only strikes moral degenerates is quite incorrect.

  89. Re:90% chance that prostitue won't kill you by tragedy · · Score: 1

    99.8% (I'm just copying your made up statistic) of car accidents COULD have been avoided as well. What's the actual point? Is it that we shouldn't bother developing an AIDS vaccine? Should we similarly not bother trying to make cars safer since people could just drive more carefully? In fact, people could abstain from driving altogether and all car accidents would go away (unless it still counts when a tornado drops one on someone).

  90. Re: God 1,800,000, Science 0 by Lucractius · · Score: 1

    Actually there was 1 case of a deliberate cure...

    but well you have to get leukemia in order to be eligible... So i dont think you can really offer it to just anyone.

    --
    XML - A clever joke would be here if /. didn't mangle tag brackets.
  91. that depends by justforgetme · · Score: 1

    I think GP found 'a dumb' and is pushing it on his parent

    --
    -- no sig today
  92. Re:90% chance that prostitue won't kill you by felipekk · · Score: 1

    I wish I could mod you -1 Naive.

  93. Re:90% chance that prostitue won't kill you by felipekk · · Score: 1

    And even then (after testing) you can't be sure because of the window period:

    "Antibody tests may give false negative (no antibodies were detected despite the presence of HIV) results during the window period, an interval of three weeks to six months between the time of HIV infection and the production of measurable antibodies to HIV seroconversion."

    http://en.wikipedia.org/wiki/HIV_test#Window_period

  94. Re:90% chance that prostitue won't kill you by felipekk · · Score: 1

    99% chance that she won't kill you?

    Don't pay that bitch and you'll see how likely she is to kill you, vaccinated or not!

  95. Rendering the body immune to HIV? by lord+sibn · · Score: 1

    What would that mean for this?
    https://www.xkcd.com/938/

  96. Can I just say by fireylord · · Score: 1

    whoosh? :)

  97. well partially right by fireylord · · Score: 1

    Substitute 'Medicine' for 'Science' and you're in the main right, and why should it be any other way?

  98. Re:90% chance that prostitue won't kill you by Phoghat · · Score: 1

    Qu'ell Schmuck !

    --
    Think of how stupid the average person is, and realize half of them are stupider than that.
  99. Re:90% chance that prostitue won't kill you by StikyPad · · Score: 1

    I'm not sure, but keep it up -- she hasn't cheated on me yet!

  100. Re:90% chance that prostitue won't kill you by Phoghat · · Score: 1

    And don't ever get sick enough to need a blood transfusion.

    Oh, and don't ever work in the health industry or volunteer anywhere that you could accidentally come in contact with infected blood.

    Are you trolling or just that naive?

    Little of both actually, with a touch of insanity, just for the flavor of course.

    --
    Think of how stupid the average person is, and realize half of them are stupider than that.
  101. Then there's the controversy... by bsquizzato · · Score: 1

    Even if a vaccine ever ends up being approved for HIV, there's no doubt that there is going to be a whole wave of controversy around actually vaccinating people, as is the case with the HPV vaccine. Since so many parents think that vaccinating their kids for HPV is just giving them another "green light" to have sex when they're younger, I am sure the HIV vaccine would be met with that same response, if not an even greater one. It will be a huge hindrance to a great achievement.

  102. Re:90% chance that prostitue won't kill you by _0xd0ad · · Score: 1

    No... This is slashdot. It's really bad at displaying characters like the superscript 2 which would have made GP's post correct.

    (1 - 90%)^2 = 1 - 99%

  103. Re:90% chance that prostitue won't kill you by Yert · · Score: 1

    Yeah, those dirty diabetics were cursed by God anyways, so they don't count, right? Or they're in unhealthy relationships. Or both. Goddamned dysfunctional diabetics. Fucking junkies.

    --
    Truck driver, plumber, Linux systems engineer.
  104. Needles by mr.mctibbs · · Score: 1

    Good euphemism.

  105. Re:90% chance that prostitue won't kill you by Grizzley9 · · Score: 1

    No because you should probably more careful than trying to fulfill what you think of as an immediate sexual desire.

  106. Re:90% chance that prostitue won't kill you by TheCRAIGGERS · · Score: 1

    You can be a Good Christian(tm) and still get AIDS from your fallen-from-grace spouse.

    That's ok. Good Christians know that everything that happens to them is part of God's Plan (tm). So it's alright to contract HIV from your cheating bastard of a spouse.

  107. Re:90% chance that prostitue won't kill you by kimvette · · Score: 1

    That's just the USA, right? How about African regions?

    http://pathmicro.med.sc.edu/lecture/hiv5.htm

    Africa

    In sub-Saharan Africa, there are an estimated 22.5 million (range: 20.9 million–24.3 million; 2007 figures) people infected by HIV with over 2.8 million new infections in 2006. In this region, there were 2.1 million deaths (figure 11 and 12). Ten million young Africans between the ages of 15 and 24 and 3 million children are infected. In contrast to western countries, young African women are more likely to be infected with HIV than young men. According to UNAIDS, 61% of HIV-infected people in sub-Saharan Africa are female and the gap is increasing. Women are being infected with HIV at an earlier age than men in most countries in sub-Saharan Africa. The differences in infection levels are most pronounced among young people (aged 15 – 24 years) with, on average, 36 young women living with HIV for every 10 young men in sub-Saharan Africa.

    Check out this one:

    http://www.avert.org/safricastats.htm

    From 2008:

    65,646 deaths of children age 0-9

    http://www.avert.org/hiv-aids-africa.htm

    Sub-Saharan Africa is more heavily affected by HIV and AIDS than any other region of the world. An estimated 22.5 million people are living with HIV in the region - around two thirds of the global total. In 2009 around 1.3 million people died from AIDS in sub-Saharan Africa and 1.8 million people became infected with HIV. Since the beginning of the epidemic 14.8 million children have lost one or both parents to HIV/AIDS.1

    The social and economic consequences of the AIDS epidemic are widely felt, not only in the health sector but also in education, industry, agriculture, transport, human resources and the economy in general. The AIDS epidemic in sub-Saharan Africa continues to devastate communities, rolling back decades of development progress.

    Sub-Saharan Africa faces a triple challenge:

            Providing health care, antiretroviral treatment, and support to a growing population of people with HIV-related illnesses.
            Reducing the annual toll of new HIV infections by enabling individuals to protect themselves and others.
            Coping with the impact of millions of AIDS deaths2 on orphans and other survivors, communities, and national development.

    Again, it's well worth finding a sure-fire preventive vaccine to protect everyone, regardless of whether or not you personally think they deserve it. Eliminating HIV is good for all health care workers who come into contact with HIV carriers, and for everyone else those health care workers come into contact with, everyone who uses public restrooms (due to the infinitesimal chance of contracting HIV from hard surfaces), everyone who might be a "good samaritan" and help someone at a car accident, a slip-and-fall, work mishap, etc., and for nice folks who have a lying, cheating husband|wife|bf|gf.

    --
    The Christian Right is Neither (Christian nor right). See: Matthew 23, Matthew 25, Ezekiel 16:48-50
  108. Public by luisdom · · Score: 1

    What? An underfunded public organisation has made this breakthrough before big pharmas?
    These spanish boffins are very smart or big pharmas don't have much interest in a HIV vaccine...

  109. Re:90% chance that prostitue won't kill you by victorhooi · · Score: 1

    heya,

    Hmm, ok, so the parent was a bit sensationalist with the 100% claim, and the pseudo-moral overtones are a bit weird.

    But he does have a point - practice safe sex goes a long way to cutting down on HIV.

    You can talk all you want about all the other possible transmission vectors, but in the grand schema of things, they're a drop in the ocean compared to the number of cases via unsafe sex.

    And look, at the end of the day, a person who screws around and does it with random people from bars is a lot likely to contract HIV (or some other STI) than somebody who stays married to the same person for 55 years and doesn't cheat. And this is a broad brush, but that sort of person is probably not likely to get random tattoos every Sunday, or engage in drugs or other risk-taking behaviour.

    Like it or not, but as humans, we do reap what we so. Sure, it all boils down to percentage. But you don't do stupid things - whether it's drugs, tattoos, or jumping out of buildings or cagefighting - and chances are, your odds are less of stupid things happening to you. Of course, I'll be the first to admit that stupid things can often be fun or tempting *grins*. But meh, that's life for you.

    Cheers,
    Victor

  110. Re:90% chance that prostitue won't kill you by S.O.B. · · Score: 1

    If the OP had presented the argument the way you did then I would have agreed.

    Unfortunately overly simplistic, uninformed opinions repeated often enough seem to become fact. I was just injecting a bit of knowledge into the hyperbole.

    --
    Some of what I say is fact, some is conjecture, the rest I'm just blowing out my ass...you guess.