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MIT Study: Prolonged Low-level Radiation Exposure Poses Little Risk

JSBiff sends this quote from MITnews: "A new study from MIT scientists suggests that the guidelines governments use to determine when to evacuate people following a nuclear accident may be too conservative. The study (abstract), led by Bevin Engelward and Jacquelyn Yanch and published in the journal Environmental Health Perspectives, found that when mice were exposed to radiation doses about 400 times greater than background levels for five weeks, no DNA damage could be detected. Current U.S. regulations require that residents of any area that reaches radiation levels eight times higher than background should be evacuated. However, the financial and emotional cost of such relocation may not be worthwhile, the researchers say."

97 of 142 comments (clear)

  1. As opposed to... by Anonymous Coward · · Score: 1, Insightful

    ...the financial and emotional cost to the unfortunate statistical cancer patient and family.

    How about this: Do not force evacuation, but provide the necessary resources for those who want evacuation (which will be all the folks with an 80 IQ or higher).

    1. Re:As opposed to... by Anonymous Coward · · Score: 2, Insightful

      Because people with an 80 IQ or higher don't understand statistics, don't trust science, or what?

    2. Re:As opposed to... by YodasEvilTwin · · Score: 5, Insightful

      Funny, but "no detectable DNA damage" is not the same as "no DNA damage or other side effects". This study would need to be much longer term and need to look for more than obvious DNA damage for me to trust it, personally. It was only 5 weeks!

    3. Re:As opposed to... by Anonymous Coward · · Score: 1

      I'll stay - my neighbors' houses aren't gonna loot themselves!

    4. Re:As opposed to... by ozmanjusri · · Score: 3, Insightful

      This study would need to be much longer term and need to look for more than obvious DNA damage for me to trust it,

      This study will never be trustworthy.

      The danger to civilians from a nuclear accident is unlikely to come from background dose. That's more likely to be the exposure mode for workers and people very close to the incident.

      found that when mice were exposed to radiation doses about 400 times greater than background levels for five weeks, no DNA damage could be detected.

      No surprises there, but they didn't test what would happen when the mice ingested radioactive particulates, or when their entire food chain or water table was contaminated. Those are the real dangers from nuclear accidents.

      --
      "I've got more toys than Teruhisa Kitahara."
    5. Re:As opposed to... by Anonymous Coward · · Score: 5, Informative

      Are you talking about chemical poisoning, or magical evil pixie dust. 125I decays emitting low-energy gamma radiation (the type that gets adsorbed adversely by living things). Eating this will have no different an affect than living right under it, as an object like a person, or mouse, is not a relevant shield for gamma radiation.

      Now, if we were talking about inhaling dusted alpha emitters, then you'd have a point. However, those are either heavy metals, oxidize and drop out of the air, or decay rapidly to long-term emitters. The dust will be much more poisonous than dangerous as a radioisotope.

      Damnit, I fed the troll.

    6. Re:As opposed to... by ozmanjusri · · Score: 3, Informative
      A recently published study in the Journal of Environmental Radioactivity confirms that the radioactive fallout from the Fukushima nuclear disaster reached Europe (Lithuania), and included plutonium. Likewise strontium (89 and 90) levels were elevated globally.

      The amounts were tiny, but randomly sized/distributed particulates are notoriously hard to measure and map.

      --
      "I've got more toys than Teruhisa Kitahara."
    7. Re:As opposed to... by Anonymous Coward · · Score: 1

      Oh please, you're not +3 insightful, you're an idiot. "background dose" is a unit, and refers to the average background radiation exposure of 360 mrem per year. It is not a dose that you are exposed to unaware in a nuclear accident. When mice are given are given 400 times the background dose it means they are given 400 mrem per day.

    8. Re:As opposed to... by spike+hay · · Score: 3, Interesting

      Do you live near a freeway? That doubles the rate of atherosclerosis. Air pollution kills hundreds of thousands a year in the US, and also causes other significant morbidity like asthma in children. Way more dangerous that a measly radiation dose. Yet, I don't see people wanting to evacuate from around coal plants and freeways.

      --
      If you don't understand any of my sayings, come to me in private and I shall take you in my German mouth.
    9. Re:As opposed to... by budgenator · · Score: 3, Informative

      Funny, but "no detectable DNA damage" is not the same as "no DNA damage or other side effects". This study would need to be much longer term and need to look for more than obvious DNA damage for me to trust it, personally. It was only 5 weeks!

      Not that much longer, a mouse goes from infancy to maturity in about 6 to 10 weeks, a year can get you a generation or two. A mouse can have 5 - 10 litters in a year and their lifespan is 9 to 12 months; 5 weeks for a mouse is like 20 years for a human.

      --
      Apocalypse Cancelled, Sorry, No Ticket Refunds
    10. Re:As opposed to... by Anonymous Coward · · Score: 1

      Colorado State University has done a large-scale, birth-to-death study of beagles exposed to low-level ionizing radiation; here's one publication:http://www.ncbi.nlm.nih.gov/pubmed/10490210

      Not good.

    11. Re:As opposed to... by Diamonddavej · · Score: 3, Informative

      Sophisticated molecular and genetic analyses were not available in 1950s - 70s when many experiments investigating the effects of radiation on plants and animals took place; most were crude LD50 and cancer frequency tests conducted at moderate to very high doses, few were conducted at low doses (0.1 Gy) where cells could potentially repair the damage caused. This has all changed in the last ~20 years.

      Sophisticated laboratory techniques now detect and observe the defence & repair mechanisms that operate in cells and whole organisms at low doses (100 mSv, ~0.8% increased risk of cancer in humans). For example, healthy people's cells repair all radiation induced DNA Double Strand Breaks (DSBs) within 24-hours after a CAT scan, indicating little or no additional risk of cancer. It is clear from resent experiments that living organisms are not passive accumulators of radiation damage but they actively combat and repair the damage done. After all, life involved with radiation and 3.5-3.8 billion years ago radiation levels were many times greater then now, it was necessary to evolve sophisticated error correction mechanisms. Indeed, it is likely that radiation is far less harmful or harmless below a certain threshold, possibly ~ 20 mSv year.

      Crump, K. S. et al. 2012. A Meta-Analysis of Evidence for Hormesis in Animal Radiation Carcinogenesis, Including a Discussion of Potential Pitfalls in Statistical Analyses to Detect Hormesis. Journal of Toxicology and Environmental Health, Part B 15, 210–231.
      Neumaier, T. et al. 2012. Evidence for Formation of DNA Repair Centers and Dose-Response Nonlinearity in Human Cells. PNAS 109, 443–448.
      Löbrich, M. et al., 2005. In vivo formation and repair of DNA double-strand breaks after computed tomography examinations. Proceedings of the National Academy of Sciences of the United States of America 102, 8984 –8989
      Tubiana, M., Feinendegen, L. E., Yang, C. & Kaminski, J. M., 2009. The Linear No-Threshold Relationship Is Inconsistent with Radiation Biologic and Experimental Data. Radiology 251, 13–22. (Paper available without subscription).

    12. Re:As opposed to... by rrohbeck · · Score: 1

      You can have them but only with Tritium, which wears out within a couple years, not anything more potent.

    13. Re:As opposed to... by davester666 · · Score: 1

      Um, yes, they do. They just can't afford to.

      --
      Sleep your way to a whiter smile...date a dentist!
    14. Re:As opposed to... by ozmanjusri · · Score: 2

      you're an idiot. "background dose" is a unit, and refers to the average background radiation exposure of 360 mrem per year.

      I keep forgetting that you have to explicitly explain everything on Slashdot or you'll be challenged on every minuscule aspect of your comment. Nevertheless, please read the Wikipedia article on background radiation, specifically the Human-caused background radiation section. http://en.wikipedia.org/wiki/Background_radiation.

      But I'll repeat: Measuring the effect of steady-state external radiation, as this study has done, gives almost no insight at all on the effect of ingesting alpha-emitting particulates. It would be ridiculous to base public policy on it.

      To trust the study from TFA would be about as sensible as measuring average wave heights off Honshu for 20 years, and concluding it would be a safe place to build a nuclear reactor.

      --
      "I've got more toys than Teruhisa Kitahara."
    15. Re:As opposed to... by Anonymous Coward · · Score: 2, Interesting

      Right, what special magical property of the environment is this that relegates 'particles contributing to background radiation' external to humans? You do know that the primary culprit in 'background radiation' is radon GAS (e.g. an inhalant)...

      And ultimately you are making an assumption not in evidence (e.g. that 'natural sources' of radiation are primarily absorbed externally while radiation doses from some 'accident' are primarily ingested or inhaled...not necessarily true in either case).

    16. Re:As opposed to... by Anonymous Coward · · Score: 1

      Really? Geez, let's be self evident...you never base 'public policy' off of 1 study...the researchers clearly indicate a need for further study...but the data point is valuable, especially when juxtaposed against the FUD generated by people such as yourself...in fact the study gives 0 evidence of the effect of 'ingested alpha-emitting particles' since that's not what was tested...but that's like saying basing policy for cyanide ingestion on an arsenic study is 'wrong'..DUH! of course it would be...

      The study can be trusted in the realm that the study was done...which is valuable and important....

      Lastly for your comments to have any validity you have to demonstrate that radiation exposure due to ingestion is a significant contributor after a radiation accident...

    17. Re:As opposed to... by ozmanjusri · · Score: 2

      Really? Geez, let's be self evident...you never base 'public policy' off of 1 study.

      From TFA "A new study from MIT scientists suggests that the guidelines governments use to determine when to evacuate people following a nuclear accident may be too conservative."

      People are suggesting public policy should be influenced by it.

      They are wrong.

      --
      "I've got more toys than Teruhisa Kitahara."
    18. Re:As opposed to... by Anonymous Coward · · Score: 1

      Did you read the study linked to? it references mean doses of 16.8 & 83.6 cGy delivered as 'one dose' at various stages of prenatal and postnatal development of the entire population, particularly at times when the beagles would be more susceptible than the 'general population'...stated this as 'not good' is way overstating any conclusions...in fact the study in this posted article is specifically looking at the opposite effect 'low dose over a long time period' (equivalent of 105 cGy/year not anywhere close to the doses described in your linked article)...effects of 'low dose immediate exposure' have been well studied, those effects are rarely in question...but that's not the most likely dose profile to a population due to a nuclear accident...

      In any case, interesting link for what I read, also it wasn't truly about the effects of irradiation but rather trying to determine a better categorization of mammary cancers...a very important effort in it's own right in order to decide on treatment (if needed) as early as possible after detection of potentially anomalous cells (not all lesions are cancerous, and not all will metastasize to be a problem, figuring out which ones will be a problem as early as possible is incredibly important).

    19. Re:As opposed to... by HuguesT · · Score: 1

      Actually, based on the abstract, the article does not talk about the influence of radiation.

    20. Re:As opposed to... by BlackPignouf · · Score: 3, Insightful

      5 weeks for a mouse is like 20 years for a human.

      Maybe, but 5 weeks for mouse's DNA is like 5 weeks for human's DNA.

      It's like the birds and rodents living happily in Chernobyl.
      Who cares if you get a cancer after 15 years of radiation if your average life expectancy is 10 years?

    21. Re:As opposed to... by msobkow · · Score: 2

      Mice may not live long, but genetic damage will still take the as long to occur in mice as in humans. The fact that humans live longer means the damage has longer to accumulate.

      So while 5 weeks may be "20 years" for a mouse's life span, it's still only a miniscule fraction of a human's lifetime in terms of how long damage has been accumulating.

      The results of this study aren't merely questionable, they're completely useless.

      --
      I do not fail; I succeed at finding out what does not work.
    22. Re:As opposed to... by h4rr4r · · Score: 1

      No, it does not. It is correlated with a doubled risk, this is also explainable that poor people tend to live near freeways. That land is cheaper, so they get it.

      Unless you have a real study proving otherwise, meaning they controlled for income, level of activity, and diet. For more than 1 human generation.

    23. Re:As opposed to... by Luckyo · · Score: 1

      This is literally examining the molecules on the wall to find out why the room stinks when there's an elephant in the middle of the room shitting all over the floor. You may find some residual fecal matter from someone not washing their hands properly after leaving the bathroom. But that won't be the main reason for the stink. In fact, it won't be stinking because there won't be enough of them to register in anyone's noses.

    24. Re:As opposed to... by spike+hay · · Score: 2

      So why does society decide that it makes sense to evacuate people from around Fukushima but not freeways if the risk is similar?

      --
      If you don't understand any of my sayings, come to me in private and I shall take you in my German mouth.
    25. Re:As opposed to... by Muad'Dave · · Score: 1

      125I decays emitting low-energy gamma radiation (the type that gets adsorbed adversely by living things). Eating this will have no different an affect than living right under it...

      Not totally correct. 125I will be selectively absorbed by the thyroid gland which will experience a much higher effective dose than any other part of the body. Similarly, the isotopes of strontium (90Sr is the main culprit) are similar enough to calcium that the bones absorb them preferentially and receive a higher dose from it.

      --
      Tiller's Rule: Never use a word in written form that you've only heard and never read. You will end up looking foolish.
    26. Re:As opposed to... by Carnildo · · Score: 2

      Mice may not live long, but genetic damage will still take the as long to occur in mice as in humans. The fact that humans live longer means the damage has longer to accumulate.

      So while 5 weeks may be "20 years" for a mouse's life span, it's still only a miniscule fraction of a human's lifetime in terms of how long damage has been accumulating.

      Humans have *much* stronger anti-cancer mechanisms than mice. A mouse in its natural environment will take about three years to accumulate enough unrepaired DNA damage to get cancer; a human takes about 60 years. Five weeks of an elevated dose for a mouse is equivalent to about two years for a human, assuming the linear no-threshold model (the model that's the basis for public policy).

      --
      "They redundantly repeated themselves over and over again incessantly without end ad infinitum" -- ibid.
  2. 5 weeks = long term? by AmiMoJo · · Score: 3, Insightful

    The article says low levels of exposure for five weeks resulted in no DNA damage. Five weeks is nothing, people living in contaminated areas will be there for years, and once radioactive material gets inside them it will be there for the rest of their lives. That is where the biggest danger is, long term internal exposure to material absorbed by the body into the organs.

    --
    const int one = 65536; (Silvermoon, Texture.cs)
    SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    1. Re:5 weeks = long term? by Rising+Ape · · Score: 5, Interesting

      The interesting thing to note (if this study is correct) is that they observed a difference between an acute dose and a chronic one. Our radiation health data is mostly based on acute doses - the Hiroshima and Nagasaki bombings, mainly. The low dose risk estimates are basically based on that, extrapolated downwards linearly.

      If acute dosing behaves differently to chronic, that model wouldn't be appropriate.

    2. Re:5 weeks = long term? by Charliemopps · · Score: 2

      They weren't talking about poisonous materials like iodine and strontium isotopes being released into the atmosphere. They were talking about Radiation. It says that very specifically. If radiation levels 8x greater than normal are present... evacuate. They think that should be set to 100x. Which makes sense. Would changing that regulation mean that if radiation levels were only at 10x background levels, and the sky was raining Cesium that they wouldn't evacuate? Of course not.

    3. Re:5 weeks = long term? by slinches · · Score: 2

      Yes, it is long term. At least it's long compared to the normal procedure for these types of experiments. What they were trying to determine is if the effects exposure are dependent on the rate as well as the total dose. From the linked abstract:

        "these results demonstrate in an in vivo animal model that lowering the dose-rate suppresses the potentially deleterious impact of radiation"

      This study doesn't necessarily imply that exposure to 400 times background radiation levels are safe indefinitely. They just showed that the exposure rate as well as the total dose need to be considered when assessing the danger of radiation exposure.

      --
      Knowledge Brings Fear
    4. Re:5 weeks = long term? by Anonymous Coward · · Score: 1

      You missed the part about 400 times higher than background levels, I take it? 400x background over five weeks, and they still can't detect DNA changes "using the most sensitive techniques available".

      If the current guidelines say 8x background levels is the max before "holy shit everyone is going to die get the fuck out now" levels of evacuation, it might just be because it's a guess erring on the side of caution. Another way to look at it: that kind of evacuation and the ensuing panic might very well kill more people than the statistical chance of getting cancer from the radiation itself, 20-40 years down the road.

      If the radiation is transient, it might make better sense for the people to stay, both in the human toll, and economic. Huh.

    5. Re:5 weeks = long term? by AmiMoJo · · Score: 1

      Where do you think radiation comes from? If there are high levels of radiation it's because there is radioactive material near by. In most accidents that material will be small enough to get inside you. That's why after you evacuate you need to wash thoroughly.

      --
      const int one = 65536; (Silvermoon, Texture.cs)
      SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    6. Re:5 weeks = long term? by demonbug · · Score: 4, Interesting

      The interesting thing to note (if this study is correct) is that they observed a difference between an acute dose and a chronic one. Our radiation health data is mostly based on acute doses - the Hiroshima and Nagasaki bombings, mainly. The low dose risk estimates are basically based on that, extrapolated downwards linearly.

      If acute dosing behaves differently to chronic, that model wouldn't be appropriate.

      Hiroshima and Nagasaki radiation victims are some of the few human models that have been studied, but the DOE (and probably other government agencies around the world) did extensive testing on the effects of radiation at various doses using animal models. In one large-scale study I know of they used two exposure groups of beagles, one using the radioactive isotopes the bomb victims were exposed to in order to establish a baseline model correlation (human effects vs. effects observed in laboratory animals) and the other group exposed to isotopes expected to result from nuclear accidents and the new generation hydrogen bombs (different fallout characteristics than the original atomic bombs). Quite a bit of research was done on this, especially during the 1960s and 1970s. They also experimented with direct gamma exposure at various levels; rumor has it (I've never seen published results on the experiments) that there was a sweet spot in the gamma ray exposure scenario that actually lead to significantly longer lifespan than the control group, with many theories as to the cause.

    7. Re:5 weeks = long term? by CrimsonAvenger · · Score: 3, Informative

      The article says low levels of exposure for five weeks resulted in no DNA damage. Five weeks is nothing, people living in contaminated areas will be there for years, and once radioactive material gets inside them it will be there for the rest of their lives.

      They also said 400x normal, rather than 8x normal.

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
    8. Re:5 weeks = long term? by hbar+squared · · Score: 5, Informative

      once radioactive material gets inside them it will be there for the rest of their lives.

      Wrong. Many radioactive isotopes aren't absorbed by the body and are flushed out rapidly, and some of the most damaging particles (alpha emitters in particular) are at their worst when airborne, only staying 'in' your body for the length of a breath. There are some isotopes that are absorbed easily (namely Iodine), but they are the minority. There is not a single "Radiation", there are a staggering number of different radioactive elements, and for each one, the chemistry matters far more than the half-life.

    9. Re:5 weeks = long term? by The+Mighty+Buzzard · · Score: 2

      Did you miss the part where they tested at 400x but the standard says 8x is too much? Over five weeks, that's roughly equal to the exposure they'd see in 4.8 years of 8x background. Assuming the food/water the mice were eating was equally contaminated, it's a pretty fair test.

      --
      Violence is like duct tape. If it doesn't solve the problem, you didn't use enough.
    10. Re:5 weeks = long term? by zeigerpuppy · · Score: 2, Interesting

      That's not the best evidence. The most appropriate literature for this exposure is that pertaining to nuclear industry workers. This is how the guidelines of 20mSv per year were derived. See this study for instance: http://www.ncbi.nlm.nih.gov/pubmed/17388693 there's no need to reinvent the wheel here, there is ample evidence that nuclear workers have higher risks of cancer and a population exposed to fallout from a reactor could reasonably be expected to have similar or worse outcomes (due to increased ingestion of isotopes)

    11. Re:5 weeks = long term? by geekoid · · Score: 4, Informative

      Maybe you, and the mods, might want to familiarize yourself with lab mice. They are precisely breed.
      We know pretty much everything about them. For example, you can get mice that will get a specific cancer at 2 months, and it happens every time. 'only' 99.9% guarantee, but I have never seen one in a control not get cancer at the expected time

      SO, for this test, 5 weeks is fine. But with ALL STUDIES, one isn't enough. DO several, control different variables, move to different species.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    12. Re:5 weeks = long term? by Rising+Ape · · Score: 3, Interesting

      That's a very difficult kind of test to do though, because making sure that radiation dose is the *only* difference between groups is virtually impossible. Even the abstract of that paper says that "Further studies will be important to better assess the role of tobacco and other occupational exposures in our risk estimates.". At least this mouse study allows for a proper controlled trial, and the Hiroshima data, while not perfect, is much less prone to such factors than your linked one.

      Also, reading the part that says "Among 31 specific types of malignancies studied, a significant association was found for lung cancer (ERR/Sv 1.86, 90% CI 0.49, 3.63; 1457 deaths)" rather reminded me of this.

    13. Re:5 weeks = long term? by Charliemopps · · Score: 1

      Get inside you? Specifically, the materials you need to worry about are materials your body uses that in their isotope form have a relatively long half life.
      Just as a rough example, if the material released from the reactor was Iodine-124, it's bad because your body does use Iodine, but it has a halflife of just a couple of days. It's not really that dangerous, and an evacuation of surrounding area would likely not be warranted if the levels are relatively moderate. If Iodine-129 is getting released, it has a half life of over 15 million years... get the hell out. The radiation level alone means nothing. Which is the point of this research.

    14. Re:5 weeks = long term? by skids · · Score: 3, Interesting

      One has to take care in this case to distinguish between the bio-retention of chemically pure compounds, and what happens in the real world, which is radioactive compounds embedded in small clumps with other material that makes them stick around, e.g. in the lungs. Especially if they get pulled through a cigarette or car engine on their way there.

    15. Re:5 weeks = long term? by Xyrus · · Score: 3, Informative

      Spoken like someone who knows nothing about radioactive materials and how they interact biologically.

      Few radioactive elements stay in the body permanently. Most of them like Cs137 and I131 cycle through the body in days to couple of months. Plutonium is one of the few that has a biological half life of significant length, and it is one of the lesser radioactive isotopes. The most likely isotope you'd encounter after a nuclear accident that has a long biological half-life is Strontium-90.

      The effective half-life of an isotope is measured by taking into account the physical half-life of the isotope and the biological half-life of an isotope. Thus, an element like Strontium 90 has an effective half-life of about 18 years while plutonium has an effective half-life of about 50 years (due to their propensity for gather in bone). Cesium has an effective half-life of about 70 days, and iodine has an effective half-life of about 7.6 days.

      With that in mind, chronic long term exposure can only occur if they are taking in enough radioactive materials to replace those that are expelled from the body. To accumulate, you'd need to be taking in more.

      --
      ~X~
    16. Re:5 weeks = long term? by Diamonddavej · · Score: 3, Insightful

      Interesting. But while there were very many experiments carried out in the 1960-70s, the radiation doses applied were generally much higher then the background levels we are interested in now. People are worried over a few extra MiliSieverts a year.

      Scientists in the 1960-70s were were not able to observe subtle cellular effects, typical defence and repair mechanisms, that operate at and just above background levels of radiation (20 mSv). They were mostly crude LD50 and cancer frequency tests. Very few experiments investigated doses 0.1 Gy (about 100 mSv & 0.8% increase in human cancer risk). And the few experiments that did involve low doses gave confused results because of poor statistical certainty (some even suggested Radiation Hormesis, as you alluded to).

      That's why these resent experiments are so important and interesting, they're finally investigating how organisms cope with low level radiation, and indeed they suggest the risks are grossly overestimated.

      Crump, K. S. et al. 2012. A Meta-Analysis of Evidence for Hormesis in Animal Radiation Carcinogenesis, Including a Discussion of Potential Pitfalls in Statistical Analyses to Detect Hormesis. Journal of Toxicology and Environmental Health, Part B 15, 210–231.
      Tubiana, M., Feinendegen, L. E., Yang, C. & Kaminski, J. M., 2009. The Linear No-Threshold Relationship Is Inconsistent with Radiation Biologic and Experimental Data. Radiology, 251, 13 –22.

    17. Re:5 weeks = long term? by terjeber · · Score: 1

      Correction: They radiated him, and in do doing, in sweet-spot cases, they created Super Snoopy, with cape and all, and now they won't tell us what the sweet-spots are.

    18. Re:5 weeks = long term? by LordLimecat · · Score: 1

      Rain....cesium?

      I would pay to see that. Best fireworks show ever.

    19. Re:5 weeks = long term? by afidel · · Score: 1

      To me the much more interesting studies are those being done in the Chernobyl Exclusion Zone, while they are obviously not controlled or double blind they do provide better feedback about actual contamination results than the lab experiment with a fixed gamma source.

      --
      There are 4 boxes to use in the defense of liberty: soap, ballot, jury, ammo. Use in that order. Starting now.
    20. Re:5 weeks = long term? by Rising+Ape · · Score: 1

      IIRC, for that one the exposed group had a different age profile to the unexposed group. As cancer risk increases with age, that explained the difference. Which just goes to show that the idea of a controlled experiment isn't just scientific pedantry - I doubt we'll ever get a satisfactory answer from that kind of study.

    21. Re:5 weeks = long term? by Talderas · · Score: 1

      The super sweet spot is pretty super. If you're a little off the mark you get all the super powers but you end up talking and expressing thoughts like a three year old.

      --
      "Lack of speed can be overcome. In the worst case by patience." --Znork
    22. Re:5 weeks = long term? by AmiMoJo · · Score: 1

      It isn't enough because with low doses of radiation the probability of DNA being damaged in a way that leads to cancer over a five week period is very low. They want to extrapolate from that period up to decades in humans, but the error is too great and the results don't match those we have observed in people receiving even lower levels of exposure.

      --
      const int one = 65536; (Silvermoon, Texture.cs)
      SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    23. Re:5 weeks = long term? by Talderas · · Score: 1

      I was under the impression that half life if related to how many emissions or the strength of the emission the particle will give off and it is those radiation emissions which are dangerous. It's the reason why plutonium, with a half life of 80 million years, is dangerous to the human body as a toxic agent rather than a radioactive agent. I'd suspect that I-129 with a half life of 15 million years is either mostly harmless since the body does use iodine but if it is harmful that is most likely to come from toxicity and poisoning rather than radiation.

      --
      "Lack of speed can be overcome. In the worst case by patience." --Znork
    24. Re:5 weeks = long term? by Jagen · · Score: 1

      If Iodine-129 is getting released, it has a half life of over 15 million years... get the hell out.

      Why? With the half life being that long and it being a low energy beta and gamma emitter which decays to a stable Xenon what's to worry about?

    25. Re:5 weeks = long term? by Diamonddavej · · Score: 1

      The problem with these studies is that they don't test the particular conditions people are worried about: long term low level exposure due to radiation inside the body and organs. Nuclear plant workers are the best benchmark we have for that, and sure enough rates of cancer are pretty consistently shown to be higher among that group.

      That's not right.

      1. The risks of internal radiation are reasonably well understood from observations of patients given injections of ‘Thorotrast’, Radium dial painters exposed to 226 Ra and 228 Ra & patients given 224 Ra for medical conditions, occupational exposure of uranium miners to radon, and residential radon exposure etc.

      Harrison, J. & Day, P., 2008. Radiation doses and risks from internal emitters. Journal Of Radiological Protection, J. Radiol. Prot., 28, 137–159.

      2. Nuclear plant workers consistently have much better health (e.g. a lower cancer rate) then the general population (McGeoghegan et al. 2008). It's called the Healthy Worker Effect, it's one of the reasons why detecting elevated risks amongst nuclear workers is difficult. However, the few exceptions are subset of rare blood cancers e.g. Leukaemia, possibly lung cancer and heart disease. Even then, the detection of a statistically significant increases are limited to a few workers in the highest dose categories, >100 mSv for rare types of cancers & >300 mSv for Heart Disease. Note that cancer risk varies ~40% due to non-radiation effects (lifestyle and environment) and overwhelm the subtle effects (if any) of very low level radiation (below 100 mSv).

      "Even a study of millions of workers exposed to very low doses (below 100 mSv), no matter how carefully conducted, would be inadequate to produce precise and uncertain estimates of risk in part because of the dominating influence of any subtle biases or unknown confounding factors" (UNSCEAR 2008, Land 1980).

      The last and biggest study into Nuclear workers, "The 15 country Study" by Cardis et al. 2005 tracked the heath of up to 407,391 workers over 5.2 million person years, was revealed to be flawed by erroneous data in the Canadian cohort (involving 11,907 workers). Cardis et al. claimed, oddly, that all cancers except Leukaemia were elevated due to radiation (and there didn't even seem to the a threshold!). But when the erroneous Canadian data was identified and removed, there was no statistically significant increase in cancer. This fiasco highlights the sensitivity to confounding, bias and error in studies of low statistical certainty. Furthermore, Boice 2010 explained that there may never be another study of nuclear workers of this size, because the permitted exposures to workers are now far more stringent and few workers will ever be exposed to >100 mSv (or even >300 mSv) to detect the effects of radiation with statistical certainty (even considering the recent events in Japan).

      So we have no direct evidence that a dose below 100 mSv causes cancer, that's why laboratory studies are so important, where we can investigate cellular repair and defence mechanisms that may cause radiation risk to depart from LNT i.e. threshold or hormesis.

      Ashmore, J. P., Gentner, N. E. & Osborne, R. V., 2010. Incomplete data on the Canadian cohort may have affected the results of the study by the International Agency for Research on Cancer on the radiogenic cancer risk among nuclear industry workers in 15 countries. Journal of Radiological Protection 30, 121–129.
      Boice, J. D. 2010. Uncertainties in studies of low statistical power. J Radiol Prot 30, 115–120.
      McGeoghegan, D., Binks, K., Gillies, M., Jones, S. & Whaley, S., 2008. The Non-Cancer Mortality Experience of Male Workers at British Nuclear Fuels Plc, 1946–2005. Int. J. Epidemiol. 37, 506–518.

    26. Re:5 weeks = long term? by DrJimbo · · Score: 1

      The low dose risk estimates are basically based on that, extrapolated downwards linearly.

      This is false. What you are describing is the linear no-threshold model which was proposed by rabid anti-nuke fanatics years ago and rejected by the industry and by regulators alike. The threshold below which radiation levels were considered to be safe has decreased by orders of magnitude as more information was gleaned about health effects of low level radiation. The assumption by the industry has almost always been that adverse health effects magically vanish unless there is scientific proof that they don't.

      There has been a battle waged for many years trying to get the nuclear industry and government regulators to accept the linear no-threshold model as the best and safest way to extropolate from high dose health effects to low dose effects.

      --
      We don't see the world as it is, we see it as we are.
      -- Anais Nin
    27. Re:5 weeks = long term? by terjeber · · Score: 1

      As long as I get the cape...

  3. Why Should I Trust This Study by medv4380 · · Score: 2

    Given the number of times one experts study is tossed out by another experts study why should I trust this 1 study, and what kind of assurances does anyone have that their isn't some kind of error and will be tossed out or ignored with the next study. How am I to know if this study wan't done to justify low level back scatter scanners at air port, and has fallen victim to confirmation bias of one form or anther?

    1. Re:Why Should I Trust This Study by AmiMoJo · · Score: 1

      Quotes like this don't exactly add credibility:

      My guess is that you could probably leave the mice there indefinitely and the damage wouldnâ(TM)t be significant

      --
      const int one = 65536; (Silvermoon, Texture.cs)
      SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    2. Re:Why Should I Trust This Study by Anonymous Coward · · Score: 1

      I agree. Last I checked I wasn't a mouse. I don't really care if one of the greatest survivors on Earth handle radiation. Might as well tell me how high the background radiation can get for cockroaches before you can detect damage. That wouldn't be a good danger level for a human. As someone whose worked with people who sued to do some very expensive studies for drugs, human trials very frequently turn out different than animal trials, even on things where the best prior research shows a strong correlation between corresponding systems in lower animals. Maybe this is a good, accurate representation, but maybe not, and would you risk your life on that assumption? How about your family's?

    3. Re:Why Should I Trust This Study by godrik · · Score: 3, Insightful

      Probably you should not trust that one study. Currently, that is the only study that lead to this conclusion. Public safety regulation should not be lowered based on a single study.

      Once the result has been succesfully reproduced in multiple independent labs, then the question will be different.

    4. Re:Why Should I Trust This Study by CrimsonAvenger · · Score: 2

      Given the number of times one experts study is tossed out by another experts study why should I trust this 1 study, and what kind of assurances does anyone have that their isn't some kind of error and will be tossed out or ignored with the next study. How am I to know if this study wan't done to justify low level back scatter scanners at air port, and has fallen victim to confirmation bias of one form or anther?

      So, why should you believe that 8x normal level is a reasonable limit? It's not like there's any evidence that 8x is meaningfully better than 9x, or meaningfully worse than 7x....

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
    5. Re:Why Should I Trust This Study by the+eric+conspiracy · · Score: 1

      This is why I don't pay attention to ANY popularized publication of scientific results.

      BPA - causes all sort of problems.

      Eating GMO corn - rat livers have problems

      Vaccine - causes autism

      Yadda yadda, every day in the news. Then you dig into the toxicological assessments of the collected studies and you find - BPA, not one of the studies was reproducable. GMO corn study had bogus statistics used to manipulate results. The vaccine study was out and out fraud.

      The answer lies in reading the toxicology journals where the assessments of the body of the studies are done. And of course this is exactly what the popular press doesn't report because these assessments generally come to the conclusion there isn't real evidence for a problem. If there isn't anything alarming or sensational it doesn't get into the news.

    6. Re:Why Should I Trust This Study by geekoid · · Score: 1

      I pay attention, mostly to prepare for the on rush of people talking about it.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    7. Re:Why Should I Trust This Study by Anonymous Coward · · Score: 2, Insightful

      The relevance of this study is not being questioned because of a concern of reproducibility but of the idea that a minor study where five weeks of exposure to a specific quantity of radiation was not found to have caused detectable disruption to genetic heredity would become equatable to saying that any low level radiation exposure is not worth being concerned enough about to inform or evacuate an area over. Their data is a single point on the scale of duration and quantity of exposure, and for each reproduction, a more statistically precise understanding can be attained.

    8. Re:Why Should I Trust This Study by h4rr4r · · Score: 1

      Why is safe land not also possible polluted with radiation?

      Bananas are safe and radioactive. So are those lovely salt replacement products.

      As to your safety margin, totally pointless. If they lie about a hundred fold increase, why not lie about a million fold one?

  4. It's alright by Panspechi · · Score: 2

    My girlfriend loves my new found third leg. Thanks, radiation!

    1. Re:It's alright by zill · · Score: 2

      Oh, now you tell me.

    2. Re:It's alright by SuperKendall · · Score: 4, Funny

      Uh, is this a penis enlargement joke? Because I don't think radiation does that.

      It does if radiation excites you sexually.

      --
      "There is more worth loving than we have strength to love." - Brian Jay Stanley
    3. Re:It's alright by bill_mcgonigle · · Score: 1

      Uh, is this a penis enlargement joke? Because I don't think radiation does that.

      Tell that to Bruce Banner. Or the ever-smiling Betty Ross.

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
    4. Re:It's alright by yndrd1984 · · Score: 1

      That depends, is a enlarged penis a super power?

      Of course it is! What kind of question is that?

  5. Magical DNA damage testing? by jminne · · Score: 2, Insightful

    How can they really test every cell to determine if there has been damage? A longer term study monitoring cancer rates would be more useful. I'm not saying that we shouldn't question the current guidelines, but changing them because of a short study like this would be crazy.

    1. Re:Magical DNA damage testing? by istartedi · · Score: 5, Informative

      If you follow the links to the abstract, it actually explains what they measured. Apparently, certain types of DNA damage leave easily measured chemical signatures. They also dosed them with the same radiation total over a short period of time and observed damage.

      This is akin to turning your thermostat up 10 degrees for a few weeks as opposed to heating your house up to 500 degrees for a minute.

      I'm not saying I want to invest in cheap Fukushima real estate. I'm just saying that maybe this science isn't as junky as some Slashdotters think.

      --
      For all intensive purposes, "whom" is no longer a word. That begs the question, "who cares"?
    2. Re:Magical DNA damage testing? by blueg3 · · Score: 2

      They can't. That's why they formulate the experiment with an appropriately-chosen hypothesis and a control.

      The question is whether the linear-to-zero dose model is accurate. It's the most conservative reasonable model and it has some experimental basis, but low-rate radiation isn't well-tested. In this model, at the low end of dosing, only the total dose, not the rate at which it's delivered, matters. (That is, you're in the "causes cancer" realm of radiation and not "radiation poisoning".)

      So, you take two populations. Expose one to a dose over a long period of time, expose the other to a dose over a short period of time. If the difference in detectable radiation-caused damage is statistically significant, you have reason to suspect that the linear dose model is inaccurate.

      When you're designing an experiment, you don't want to be working with a single population with results near your detection limit, because everything near the detection limit looks the same. (Hey, we found nothing!) Hence the carefully-chosen control or comparison group.

    3. Re:Magical DNA damage testing? by Kergan · · Score: 1

      They also dosed them with the same radiation total over a short period of time and observed damage.

      This is akin to turning your thermostat up 10 degrees for a few weeks as opposed to heating your house up to 500 degrees for a minute.

      I'm not saying I want to invest in cheap Fukushima real estate. I'm just saying that maybe this science isn't as junky as some Slashdotters think.

      If I put an egg in warm water for a few hours, I'll have the same egg -- one that I can use to make an omelette. If I put it in boiling water for 10 minutes, I'll have hardened. Similar amounts of energy, different results.

      A 400x radiation dose over 5 weeks does not necessarily a long term 8x dose make, and Slashdotters are absolutely correct to call this out.

    4. Re:Magical DNA damage testing? by Carnildo · · Score: 1

      A 400x radiation dose over 5 weeks does not necessarily a long term 8x dose make, and Slashdotters are absolutely correct to call this out.

      That sort of comparison is exactly what this study is calling out, too. You know how that "8x background = evacuation" threshold was developed? By measuring the effects of a short-term dose just low enough to avoid acute radiation poisoning, and assuming it's equivalent to a low-level long-term dose that provides as much total radiation. (It's called the "linear no-threshold model". Look it up.) You're correct to say that 120 millisieverts over the course of 5 weeks (the study dose) isn't equivalent to 1200 millisieverts over the course of 40 years (a long-term 8x dose), but 1000 millisieverts over the course of 30 seconds (a dose that won't quite trigger acute radiation poisoning) isn't equivalent to it either.

      --
      "They redundantly repeated themselves over and over again incessantly without end ad infinitum" -- ibid.
  6. So.. by Anonymous Coward · · Score: 1

    The next step is to stick some Iodine-125 down the researchers pants and see how things turn out for them.

    1. Re:So.. by MightyYar · · Score: 1

      Rule 34

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  7. What is the baseline background? by Anonymous Coward · · Score: 1

    Just pointing out that in most places background is pretty low. Eight times higher in a low background area isn't the same as say eight times higher in an area that already has a higher than normal background count (for example New Hampshire, the Granite (and slightly more radioactive than normal) State.

    Also internal exposure increases the damage from radiation by a factor of ten. At a does the equivalent of 80x background, you might want to move.

  8. Unfortnately at 5 weeks... by Genda · · Score: 1

    The mice turned green, grew to immense proportions and began pimp slapping the researchers around like they were red-headed step children!

  9. Background level by Relic+of+the+Future · · Score: 4, Informative
    Seems a bunch of people really don't understand the scale of how low "background level" really is, how quickly levels can drop as the worst isotopes rapidly decay, or how the body repairs over time. That last one is maybe okay; we really haven't put a lot of study into anything beyond immediate exposures, so no one has a good understanding of that; or, I should say, HAD. And to see so many first reactions to this new science being "I refuse to believe it!"? Very disappointing. It's amazing how much disbelief a purportedly "scientific" group can conjure when scary radiation is mentioned.

    Btw, 100x background for 5 weeks is still less than the maximum year-long dose. Check the should-now-be-iconic xkcd radiation chart.

    --
    Those who fail to understand communication protocols, are doomed to repeat them over port 80.
  10. useless by spongman · · Score: 2

    it looks to me like the exposure was entirely external.

    if you're breathing, eating, drinking and washing in the source then it's much more likely to be problematic.

    1. Re:useless by Alex+Belits · · Score: 2

      And people NEVER thought about measuring food and environmental contamination with radioactive isotopes, separately from external exposure.

      Oh, wait, this is what I did at work! Twenty years ago!

      --
      Contrary to the popular belief, there indeed is no God.
  11. I'm fine with that, moron. by SuperKendall · · Score: 4, Insightful

    There's nothing I detest more than some douche who has spent some time
    at a university telling us all "we have nothing to fear".

    Oddly, there's nothing I detest more than some idiot who is terribly afraid of something long after it's been proven to be safe.

    I'd happily live in an area with 200x the level of background radiation (hey, my AT&T reception couldn't get any worse). The best benefit is that I can be sure compete morons like yourself will not be neighbors.

    They said that about DDT.

    Um, yeah...because DDT is safe. And millions have been killed from malaria that could have been saved without idiots like yourself "protecting" them.

    Moron.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley
    1. Re:I'm fine with that, moron. by newcastlejon · · Score: 1

      Um, yeah...because DDT is safe

      Supporting those black natives, however, are two researchers, Richard Tren and Roger Bate, whose Malaria and the DDT Story, recently published by the Institute for Economic Affairs in London, shows how to foster both a healthier and an environmentally friendlier Third World. Greenpeace, in its self-assurance, embodies a contemporary cultural imperialism as offensive as any Jesuit's.

      The Telegraph at its finest.

      --
      If God forks the Universe every time you roll a die, he'd better have a damned good memory.
    2. Re:I'm fine with that, moron. by dbIII · · Score: 2

      I'd happily live in an area with 200x the level of background radiation

      Granite walled basement?

    3. Re:I'm fine with that, moron. by afidel · · Score: 2

      We need to bring back DDT for killing bed bugs! It's about the single best way to kill the things and there would be little concern of bioaccumulation in that application. Oh, and calling someone a moron and then linking to the freepers is about the funniest thing I've ever read on the internet and I've been here since 1993 =)

      --
      There are 4 boxes to use in the defense of liberty: soap, ballot, jury, ammo. Use in that order. Starting now.
    4. Re:I'm fine with that, moron. by BlackPignouf · · Score: 1

      And DDT is extraordinarily safe for humans. Prof Kenneth Mellanby lectured on it for more than 40 years, and during each lecture he would eat a pinch.

      I'm sure you could find someone who has been smoking 20 cigarettes a day for 40 years and who still is relatively healthy.
      Are cigarettes "extraordinarily safe for humans" ?
      Is falling from a 20 m roof "extraordinarily safe for humans" because some guy survived it?

      I have no clue about DDT, I'm just saying that this logic is deeply flawed.

    5. Re:I'm fine with that, moron. by ShakaUVM · · Score: 2

      >>I have no clue about DDT, I'm just saying that this logic is deeply flawed.

      It's akin to a scientist saying that it is safe to drink non-radioactive water from a nuclear power plant's cooling power, and putting his money where his mouth is by drinking it.

      It's entirely safe for humans in the dosage levels used to control bed bugs and malaria, which require much lower dosages than the wholesale blanketing of farmlands we were doing before. While it is toxic (http://en.wikipedia.org/wiki/DDT#Effects_on_human_health) the levels required are really high. The LD50 (50% chance of dying) for me would be around 30 pounds of pure DDT. When cut into a paste (1%-5% DDT), you're looking at needing to eat 600 to 3000 pounds of DDT paste to have even a 50/50 chance of dying from it.

    6. Re:I'm fine with that, moron. by h4rr4r · · Score: 1

      DDT is legal in those areas. Where does this constant bullshit lie come from?

      What talking heads are you listening too?

  12. Re:Humans have no Vitamin C, Mice have by Alex+Belits · · Score: 2

    How much energy do you think, a cell has to absorb for any of this "oxidative stress" crap to happen?

    --
    Contrary to the popular belief, there indeed is no God.
  13. Re:Humans have no Vitamin C, Mice have by geekoid · · Score: 1

    And that, ladies an gentlemen, is what happens you you derive your scientific opinion fro popular science articles.

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
  14. Re:Got what they paid for by Iskender · · Score: 1

    At Chernobyl - wildlife have been reported to have lower survival and reproduction rates, with clear pathological effects to sperm.
    This data point may be valid (it's a complex problem),

    Not a bad point, and Chernobyl should figure in most radiation data comparisons due to its nature. However, radiation levels vary wildly in the area: the animals could have eaten their food from a hotspot even if the background would have been tolerable (which we don't really know either.)

    but you have to wonder when the sponsor (DOE) reason to want this outcome.

    No we don't. But, I'll say this much: the DOE is involved with coal power. The DOE is involved with nuclear power. Clearly, they're simultaneously plotting to replace coal with nuclear and nuclear with coal.

    Also this was funded by both MIT and the DOE. This is just basic research, so cool it with the conspiracy theories.

  15. The part that gets me... by Grog6 · · Score: 1

    I work with extremely sensitive radiation detectors at work; our typical energy is gamma at 511keV.

    These gammas are derived from artificial radioactive sources, with a short half-life.

    Testing these detectors is extremely informative; natural cosmic rays are much more worrisome to me than the sources...

    I see 10-20GeV pulses at around 1-5 per minute; that's about all the energy they can dump in my detector, lol.

    2x 8" lead bricks do not appreciably attenuate these cosmics at all; amazingly, underground missile silos were built to a spec! :)

    --
    Truth isn't Truth - Guliani
  16. Low level radiation may be protective by etinin · · Score: 1

    My teacher, who has a PhD in Radiobiology, once did an experiment on the subject. He had two groups of mice. One of the groups was exposed to laser radiation. The other one was a control group. Both groups were then subjected to high energy ionizing radiation. Guess what: the ones who were exposed to the laser had a high survival rate than the ones who were not. So there is this belief that very low levels of radiation might actually activate your body's repair system without doing much damage. The caveat may be an increased incidence of mutations. We do not have many reliable methods to quantify that.

    --
    "I decided I could write something better than everything out there in two weeks. And I was right." - Linus Torvalds
  17. Diet and environment by manu0601 · · Score: 2

    Are the mice a good model for human radiation risk?

    Radiation induce cancer, but that does not mean cancer will thrive. It needs to be promoted. Diet and environment contain promoters. I suspect the mice in the experiment were not fed with growth hormone treated beef, for instance. First-world humans tend to have a diet that highly promotes cancer, therefore their risk may be higher than the mice in the study.

  18. Is decades long term ? by aepervius · · Score: 2

    If yes you might want to read this : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477708/

    --
    C. Sagan : A demon haunted world:
    http://www.amazon.com/gp/product/0345409469/
    visit randi.org
  19. Evacuate Cornwall ASAP by tp1024 · · Score: 1

    With an average 7.6mSv per year Cornwall is well above 8 times average background radiation.