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Microbiome Changes Drive the Dieting Yo-Yo Effect, Study Finds (smh.com.au)
wheelbarrio writes: We've known for a long time that diet-induced weight loss is rarely permanent but until now what has been a frustration for dieters has also been largely a mystery to scientists. A paper published today in the prestigious journal Nature presents good evidence that your gut microbiome may be to blame. Studying mice fed cycles of high-fat and normal diets, the authors found that the particular bacterial population that thrives in the high-fat regime persists in the gut even once the mice have returned to normal weight and normal metabolic function after a dieting cycle. This leaves them more susceptible to weight gain than control mice who were never overweight, when both populations are exposed to a cycle of high-fat diet. The details are fascinating, including the suggestion that dietary flavonoid supplementation might mitigate the effect. My guess is that this may end up being one of the most cited papers of the year, if not the decade.
Would also mitigate the effect
Who would have guessed.
My guess is that this may end up being one of the most cited papers of the year, if not the decade.
Not if the food processing industry has anything to say about it.
" My guess is that this may end up being one of the most cited papers of the year, if not the decade"
Is this the same as your guess that Trump supporters are racist and fascist and Trump would not win?
This might explain why some recipients of FMT for treatment of C. diff. and CU have seen weight gain without changing their diets.
I feel so sig.
Let's write a paper and try to push sales up a bit.
Sorry for being so cynical but that's how this industry operates most of the time.
diet: "way of living, mode of life". A temporary regime can be useful to recover from an illness; it doesn't permanently change the size or contents of your gut if it doesn't persist. But of course we've always known that.
People can't lose weight because they have no willpower and/or are too lazy to exercise. All other excuses are BS and for anyone who comes along and mewls that they just can't lose weight no matter what they do I just ask them to go and point out where the fatties are standing in the background of those news reports from famine hit areas. Quite.
Remember that correlation is not causation (you already knew that, right?). Low levels of flavonoids could be a consequence of the biome change, and not a cause. If so, then flavonoid-rich diets will be useless (and could even be toxic).
But in further analysis of the microbiome, they found that among key changes were [] reduced energy expenditure.
Why would you ever go on a diet without exercise? Isn't it common knowledge that you have to raise your metabolic rate?
the authors found that the particular bacterial population that thrives in the high-fat regime persists in the gut even once the mice have returned to normal weight and normal metabolic function after a dieting cycle. This leaves them more susceptible to weight gain
Because this is why people get fat. From eating fat. In other news, eating sugar causes diabetes.
Seven puppies were harmed during the making of this post.
I wholeheartedly think these studies are a scam to get further government grants in order for the creators to do nothing, repeat the process and live off the money. /tinfoilhat
Seriously, when will there be papers released with actual definitive proof and not some hypothesis that will probably be debunked by another soon enough?
speaks for locally known trusteries? cease fire stand down.. spirit of creation (all of us) provides more than enough of everything we need without any personal gain motive.. thank mom
On a hunch I decided to see if there's a correlation between obesity and antibiotics (which are known to kill both the good and bad types of gut bacteria)
Here's a map showing antibiotic prescribing rates.
http://www.cdc.gov/getsmart/co...
Here's a map showing obesity rates:
https://www.maxmasnick.com/med...
Correlation is not causation, but in my unprofessional opinion, these maps look eerily similar.
I have little doubt that you will be correct about this paper ending up cited a lot.
I decided a few years ago that my weight issues may have been due to my guts microbiome.
I began paying thin prostitues to let me eat their asses. With little change to my diet or physical activity I was able to shed enough Weight to not need to pay to lick anus.
The lifestyle change has been amazing and now I try shove my tongue in a bumhole daily.
This is a slashvertisement for whatever upcoming "flavonoid supplement" this outfit is about to come out with.
The typical concept of a "diet" (as in, temporarily changing how/what/how much you eat) is the problem here ... if you eat "a" and are fat, then eat "b" for a while to lose weight, and once you do go back to eating "a", why would you expect anything else than regaining the weight? People need to stop the concept of a diet, and instead change the way and what they eat ... there are enough studies and science around food to show that meats, sugars, fat, processed foods etc are the cause for overweight and obesity, and by changing to more nutritional-value based foods not only the body loses weight, but many other civilization sicknesses are prevented or at least greatly reduced ...
A lot of people do sports in a serious and committed manner but only a small % of them make it big. All those millions of other extremely fit people with the right microbiome will be great donors for health enhancing poop transplants.
I can't wait for people to be discussing their transplants in the same enthusiastic manner that bodybuilders talk about their supplements.
Diets that involve certain types of foods have not worked for me. Not that I am overweight by any large amount, I was just about 30 lbs more than me being at what most would consider skinny. I have been doing Intermittent fasting, which is significantly easier for me. While losing weight, about 2 Lbs a week, I eat 1 meal a day (Dinner) with very few limits on how much or what I eat during this meal. This lifestyle change was significantly easier to cope with than changing what I eat. By the time I hit the 24 hour mark my stomach seems to have shrunk so it doesn't take that much to make me full and eating a full days worth of calories would be difficult for me in one meal. I realize this is not the case for everyone. It was strange for the first couple days doing this, but my body adjusted to not expecting the food throughout the day and hunger pains went down significantly. Now that I am back to a reasonable weight I work out and do 2 meals a day which may be giving me a few too many calories, but If I notice any weight gain I can always do a couple of one meal days per week and not feel like I am the dieting rollercoaster. There are a few websites and books out there that claim it is healthy, but I am very skeptical of most all nutritional science one way or the other. My energy levels seemed OK in the dieting phase, but I am usually more physically active in the morning than in the afternoon. I'm not sure how it would go If I worked out just prior to dinner.
So would killing off your gut bacteria and then replacing them be effective? Probably the opposite is also true that antibiotics are often responsible for gut bacteria imbalances in the first place, but at some point would it be most effective to just wipe the slate clean and then 24 hours later take a pill to reestablish your gut bacteria?
I'm a bit late to the party and please note that this observation is based on a sample size of one, so take that with a spoonful of salt, however:
I've tried a few things to lose weight and I'm now below 90kg. I started at 116kg about 6 or 7 years ago. I first lost 23kg by changing my diet to less carbohydrates and more veggies and salad (where I previously ate none). I was out of a job at that time.
This diet was assisted by a doctor and I was forbidden from doing much sports.
After I got a job and relaxed on my diet regime, I gained another 10kg. I stayed at around 103 kg for quite a bit. Perhaps a year ago, I started chewing my food better and thus ate much less food. I lost weight to the point of weighing about 96kg.
Then came another tough time with the kids and I tried keeping spirits up with carbohydrates, so I remained at 96 for another while.
In last two or three months I went down to 88.8. Again by just eating less.
During the last three years, I had a brutal bout of ulcerative colitis and spent two weeks in the hospital with a blocked colon where I couldn't keep down any food for about ten days.
I weighed about 82 kg when I left the hospital but due to my lack of strength, just about all the weight lost was muscle mass, not fat. I was back on my normal weight a few weeks later.
Now my theory is this: Even though I never wanted to believe it, eating less calories than you actually burn during the day plain does work. There are two caveats though:
Without actually measuring your level of activity and your muscle mass it is a bit hard to define what your daily needs actually are.
And second, and much more important, if you suffer from depression and stress, you are much, much more likely to have to wage a HUGE internal battle with yourself to actually keep to your diet. And when you almost inevitably fail to adhere to your diet on an especially hard day, you're WAY more likely to think yourself a failure and eat too much the next day as well or even give up on the diet altogether.
And since you already failed, in your mind, you'll fall back on the carbohydrates to boost your mental stability again.
I believe, much like with every addiction, that this is primarily a mental issue. Which makes it all the harder to overcome. It's not easy being in a mentally stable state when your overweight contributes to your depression.
Gut bacteria make a huge difference and they adapt to your diet. There are companies working on transplants, so far it's pretty much consuming excrement... It's the only treatment for some diseases, notably some antibiotic resistant ones. Gut bacteria will change what you consume depending on what they consume and they can change how full you feel based on what they give off (gases...).
Antibiotics kill a lot of gut bacteria so they probably have an impact on weight gain and weight loss. They almost certainly reduce the variety of intestinal flora and that is probably a bad thing.
Recent studies show eating fat does not make you fat. The fat gets broken down and used. Eating sugar makes you fat, it gets stored quickly. Drinking soft drinks (even zero cal zero sugar) makes you fat, don't know why, studies are consistent.
Fruits, vegetables, and exercise are all good.
Walking briskly is good exercise. Walking slowly isn't.
If you want to lose weight: weigh yourself often, cut sugar, exercise. Not necessarily fun, but not bad if you can cook and find sports you enjoy, and/or learn to enjoy walking fairly fast and far.
You got me into this! You were the ideologue! I'm only a poor assassin! - Twenty evocations, Bruce Sterling
> I don't know if it's my biome, my genome, my upbringing, or what. I always feel like I could eat more.
I think right there you've identified one difference (apart from bacteria etc). I always *could* eat more too, but I wasn't raised to eat as much as I possibly can. For me, feeling stuffed is unusual and uncomfortable. For me, normal and comfortable is *some* food in my belly. I *could* drive faster, I *could* talk louder, I *could* eat more. I'd categorize my hunger/fullness in three ranges:
Hungry - stomach starts to hurt, feeling the effects of low blood sugar.
Normal - There's some food in my belly. 90% of the time. I'm not noticing my stomach or blood sugar.
Full - yuck, I ate too much. I feel kinda bloated and can't move around as well. I do this maybe once per year.
I'm sure there are several different things that affect weight, but I think that's one of them, and it's probably how different people are raised. I don't talk as loud as I can, I talk at a reasonable, comfortable level, and I was raised to eat the same way. Did your parents tell you to eat everything on your plate? I grew up leaving food on my plate, eating just until I no longer felt that I needed to eat more. I always *could* eat more, but had no reason to stuff myself.
I'm surprised this isn't the takeaway message.. Focusing on high-fat or high-protein diets is what's wrong. Instead, focus on fiber, or prebiotics - the stuff your good gut bacteria wants. Ironically, the vilification of carbs plays into this problem: most fiber comes with carbs. Brown rice, fruit, whole grains, etc.. People foolishly lump them together with processed carbs (white sugar, white rice, white flour) and then end up missing out on a lot of potential fiber. Whole grains, lots of veggies, pulses, legumes and fruit will support the microbiome you want. Some of the best advice I've heard: eat 80% 'healthy' every day, and you can slack a bit with the other 20% (although the more healthy food you eat, the less inclined you are to want the unhealthy food, as your gut resets itself.)
For the last 4 years I have been eating primal/paleo. I lost 15 pounds in the first month, and it has stayed off. I went from 175 to 160. It was not hard. It was not grueling. I did not kill myself with workouts. It is basic body chemistry - to massively simplify it, by regulating your hormones - mainly insulin - you stabilize your body's need to store fat. I can and often do go 24 hours without eating with no ill effects at all. If your body knows how to burn fat (instead of blood sugar) when you need it, this is a trivial and simple thing. It doesn't take will power - it takes knowing what to eat so that your body learns how to regulate these hormones. The cravings for those things disappear because you break the chemical addiction that your body has to them. That is not a metaphor, that addiction is real.
Watch the talk by Dr. Peter Attia on Vimeo about our "dietary guidelines". It's a good start.
Then read the books "The Primal Blueprint" and "Why We Get Fat: And What To Do About It"... throw in "Grain Brain" while you're at it.
I will not go into a diatribe, but I was never really 'overweight'. By essentially cutting out grains, many other carbs, and inflammatory foods my life has changed for the better. I will be turning 47 soon, and feel fantastic.
My beliefs do not require that you agree with them.
This is not an antiquated newspaper or Twitter. "Microbiome Changes Drive the Dieting Yo-Yo Effect, Study Finds"... are you kidding me? Either drop the "study finds" or put it in front where it belongs, and please stop with the camel case.
And a brand new excuse is born. Great...
"I'm not fat, I just have a microbiome that thrives in the high-fat regime!"
Doesn't exactly roll off the tongue, but that's all the more reason for the pseudo-intellectual shitheads we call today's youth to love it. Plus it has "micro" in there. That word seems popular these days.
In other news, how is this news? Fat people relapse because they give up on exercise and start eating again.
Low metabolism + low activity + (high food intake * high caloric content) = fat
I'd file this insignificant grain of evidence under metabolism and sweet tooth.
Also "hey fatty, why are your microbes such fatties?"
captcha: bulging
Who had thougt that reverting to the old diet habits returns you to your old weigt gains? ... what a mo brainer.
Wow
If you have successfuly changed your diet and lost your weight, you obviously should stick more or less to that diet instead of reverting to eat the unhealthy crap you ate before.
Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.