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OxyContin Billionaire Patents Drug To Treat Opioid Addiction (cbsnews.com)
Richard Sackler, the billionaire businessman behind Purdue Pharma, has patented a new drug to help treat opioid addiction (Warning: source may be paywalled; alternative source). The news of the patented form of buprenorphine, a mild opioid that is used to ease withdrawal symptoms, comes as Colorado's attorney general is suing the OxyContin creator for profiting from opioid addictions. Some now believe that Sackler and his family, who owns Purdue Pharma, will be trying to profit from the antidote. The Washington Post reports: The lawsuit claims Purdue Pharma L.P. and Purdue Pharma Inc. deluded doctors and patients in Colorado about the potential for addiction with prescription opioids and continued to push the drugs. And it comes amid news that the company's former chairman and president, Richard Sackler, has patented a new drug to help wean addicts from opioids. "Purdue's habit-forming medications coupled with their reckless marketing have robbed children of their parents, families of their sons and daughters, and destroyed the lives of our friends, neighbors, and co-workers," Colorado Attorney General Cynthia Coffman said Thursday in a statement. "While no amount of money can bring back loved ones, it can compensate for the enormous costs brought about by Purdue's intentional misconduct."
The lawsuit states that Purdue Pharma "downplayed the risk of addiction associated with opioids," "exaggerated the benefits" and "advised health care professionals that they were violating their Hippocratic Oath and failing their patients unless they treated pain symptoms with opioids," according to the statement from the Colorado attorney general's office. But Purdue Pharma "vigorously" denied the accusations Friday in a statement to The Washington Post, saying that although it shares "the state's concern about the opioid crisis," it did not mislead health-care providers about prescription opioids. "The state claims Purdue acted improperly by communicating with prescribers about scientific and medical information that FDA has expressly considered and continues to approve," a spokesman for Purdue Pharma said in the statement. "We believe it is inappropriate for the state to substitute its judgment for the judgment of the regulatory, scientific and medical experts at FDA." The report makes note of the patent's description, which acknowledges the risk of addiction associated with opioids and states that the drug could be used both in drug replacement therapy and pain management.
The lawsuit states that Purdue Pharma "downplayed the risk of addiction associated with opioids," "exaggerated the benefits" and "advised health care professionals that they were violating their Hippocratic Oath and failing their patients unless they treated pain symptoms with opioids," according to the statement from the Colorado attorney general's office. But Purdue Pharma "vigorously" denied the accusations Friday in a statement to The Washington Post, saying that although it shares "the state's concern about the opioid crisis," it did not mislead health-care providers about prescription opioids. "The state claims Purdue acted improperly by communicating with prescribers about scientific and medical information that FDA has expressly considered and continues to approve," a spokesman for Purdue Pharma said in the statement. "We believe it is inappropriate for the state to substitute its judgment for the judgment of the regulatory, scientific and medical experts at FDA." The report makes note of the patent's description, which acknowledges the risk of addiction associated with opioids and states that the drug could be used both in drug replacement therapy and pain management.
If you are a multi-billion drug lord, you are called "big pharma". If after a while your product (Heroin, Cocaine etc) is banned, you switch to something else and the "evil" drug lords that are not big enough to be called "big pharma" take over those products.
Getting rich by both getting your users addicted and also selling them treatment is a further step in this theatre of the absurd we live in...
The jails and prison will have it for free tax payers will foot the big bill
https://jamanetwork.com/journa...
You are welcome on my lawn.
Scoot Gottlieb has his priorities, and it sure doesn't seem to include getting people off of opioids.
After a relatively serious motorcycle accident (36 years ago, it's all good since...), I received a prescription for percodan. I resisted the temptation to try it for a while, but one night I caved and took the pill.
*Never Again.*
I don't know whether it was a reaction to the drug, or a small taste of withdrawal. But every cubic millimeter of my body was uncontrollably itchy, for about a day and a half. EVERYTHING was itchy. Inside and out.
Pain is nothing compared to that experience.
That said... A guy making billions peddling that shit, then patenting a drug to treat the consequences of having taken the original known-addicting drug is magically, cosmically evil.
Some bullshit slashdot commenter talking about "personal responsibility" is almost as evil. I remember the Scientific American article written about opioids back in the '90's, in which the authors declared that opioids are not really addictive for patients in real pain. I don't remember whether there were any disclaimers. Now we know they were lying. Now we know that these "trusted sources" with money to be made were fucking over their customers.
And now we have shitheads commenting with such glibness about personal responsibility. To which I reply: Piss off boy. If you are lucky enough never to have experienced it, or possibly lucky enough to have experienced it and gotten past it, that's all fine. You are the exception. But that does not give you the privilege of dismissing the effects of such executive lying on other people who for one reason or another fell victim to the Royal Scam.
The individual has to WANT to stop feeding their addiction!
Rick B.
This is just a repeat of all their former drugs.
The government should issue the patent at great cost ($1B), then ban the specific drug in question. And use the money for addiction counseling.
But of course $$$ are more important than human life in this country.
This pill to combat the addiction to the previous pills... it's addictive too, isn't it?
Amoral.
Opiods
Ignore all of what John Oliver says if you like and just watch the various clips show. It's just plain insane to argue that "Painkillers are Addictive" is a myth or rely upon a "Letters to the Editor" for your claim that only 1% of people become addicted to painkillers. One could argue that doctors and patients should have known better, and there's obviously some truth to this. But we don't grant some sort of leeway in marketing in lying just because you've demonstrated yourself to be a bald faced liar. Or perhaps I should say, we shouldn't.
Personal responsibility is at the root of addiction problem. It doesnâ(TM)t matter what companies are pedling. This is just like cigarettes - it was never a secret that they are not good for consumption. Everything else is an excuse by Americans to shift personal blame towards another entity for profit. The only people that gain from this are lawyers and politicians.
Doctor: "The good news is, we cured your Oxycontin addiction. The bad news is, now your addicted to Buprenorphine."
Doctor: "But don't worry, we have another drug to cure that."
Drop it.
...being both the arsonist and the fire-fighter and getting to profit on both sides! America, Fuck Yeah!!
Haha, this is pathetic !
If such sh!t happens in a small country, people will simply come out and there will be a public lynch for this billionaire guy.
Healthcare is really getting out-of-hand in US.
Let them die of overdose!
Personal responsibility would start with not driving or riding on a death machine.
You chose to ride a death machine and narrowly escaped. Lucky you, but anything after that is a result of your poor choice and so yes, it is on you.
he has a med which causes addiction, thus must be taken by people addicted. money. new med will stop addiction, so must be taken by people trying to end addiction. more money. third, im sure they are working on: a medication that everyone who is not an addict NEEDS TO TAKE to simply live. maybe a med which has no noticeable efffects, but could be proven in studies to reduce risk of workplace violence. so all employers would mandate all their employees take it. then you have patented oxygen, and you control all human beings.
We could build a factory and make misery We'll create the cure; we made the disease
For all intensive purposes, "whom" is no longer a word. That begs the question, "who cares"?
After a recent operation the first thing they did in the recovery room is shoot me full of opioids and I'm in commie Europe. When I went home I got a small number of oxycodone tablets for if things went off the deep end and the NSAIDs became useless (as they tend to do for serious pain). What's supposed to be the alternative?
This exemplifies everything that is wrong with your 'merka. You deserve it since you 'merkins brought it all on yourselves. Thank god the 'merkin century is over.
See? If we legalize drugs and treat addiction as a public health issue, then we can sell the drugs, tax them, and charge for treatment. That way we can exploit peopleâ(TM)s misery for financial gain. Itâ(TM)s truly a great idea!
I bet this is also why transgenderism is being normalized. Think of all the money that can be made from hormone therapy, transition surgery, psychological counseling, etc.
I live in Colorado. The alternative is fuck you, smoke some pot . I have a 2.5 cm incision in my big toe and fit dent home with just nsaids. Boehner, since I'm a pilot and put isn't an option, i guess staying drunk for a week was a "good thing ?
Fuck you Hickenlooper and your politics at any cost, and shove your rich people only toll lanes.
After the great opiod boom got rolling in the 90s, pharmaceutical companies developed new medications to combat the side effects, like nausea.
Now it's not that that anti-nausea medications for people who legitimately need to take opioids, but pharmaceutical companies aren't humanitarian organizations. They were doing this to push more oipioids, which they knew damn well were being overprescribed on a horrific scale.
Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
After a recent operation the first thing they did in the recovery room is shoot me full of opioids and I'm in commie Europe. When I went home I got a small number of oxycodone tablets for if things went off the deep end and the NSAIDs became useless (as they tend to do for serious pain). What's supposed to be the alternative?
CBD. Cannabidiol. People primarily associate marijuana with THC, which is the euphoria-inducing drug, but the other piece of marijuana is CBD, which is one, if not the most effective and non-addictive painkiller available.
https://en.wikipedia.org/wiki/...
That's where medical marijuana is finding its niche. People who need pain relief get CBD; you can get patches, ointments, tinctures, sublingual drops, pills, or vape pens. People who want to replicate opiods get CBD with a bit of THC. People with panic attacks, PTSD, mental disorders, etc get THC. The ratio of the chemical formulation provided depends on your symptoms.
Its no surprise that anti-marijuana research and lobbying is primarily funded by big pharma - its competition.
There is no alternative. No matter the painkiller*, there is the clear risk of addition and in all cases the choice of "do I risk being addicted or suffer through the pain with inadequate alternatives" should be pretty high on the list for both doctors and patients. When there is sufficient reason to take the risk, then to should be include all the steps to monitor the signs of addiction and to help guide people if they do become addicted to break that addiction.
That last thing you do is listen to Purdue Pharma, where painkillers don't become addictive and there's no real need to do intense monitoring for addiction or consider and funding the costs of breaking addictions that do occur. When you blindly listen to Pharma, you get opioid epidemics. Imagine if all that addiction treatment that everyone was getting was coming out of Pharma's pocket? Or the costs of all those premature deaths where Pharma didn't do enough to spell out the risks or enforce monitoring of possible addiction. Or maybe even, God forbid, jail time for fraud that results in death?
That's really the point.
* For any painkiller that doesn't merely mitigate pain but actually "kills" it.
Weed.
Some say weed. All it does for me is make me care a little less when I'm about to pass out.
Best pain treatment option is disrupt whatever is causing the pain. For me, that means taking north of a gram of NSAIDs every two or three hours when I need to stay conscious and symptoms come up. It's killing my kidneys and creating ulcers, but the alternative is opioid addiction and unemployment.
Weed is not painkiller. In fact it makes burns much more annoying.
When i was given opiods for shingles, nothing was mentioned to me. Now I understand pharmacology enough to use the smallest dose possible and only used half the prescribed dose by the end. The instructions were to take it regularly, which is a good way to setup an addiction. I took it only as needed which was much less frequently. Same went for the OTC stuff they prescribed too.
Now the doctors *should* know better, but they are overworked which is another topic altogether.
You are exactly the sort of person who is sure all paraplegics are just lazy and could stand up if they set their minds to it.
We see this happening before, all that family should be in jail, they have killed more people than we knowledge and still do.
We'll create the cure; we made the disease.
-- Soul Asylum; Misery, 1995.
It's a perfect time for being wasted.
A perfect time to watch the stars.
- Burden Brothers, "Beautiful Night"
The fact is, the way things are now, you'd have to be incredibly naive to actually trust doctors' recommendations regarding drugs. In America, you must assume everything you interact with is for-profit, including medical systems. If you don't research every drug you're going to be using quite thoroughly on your own, you are in for some hurt or addiction, as in the case with opiate abuse. I once had some shifty Chinese doctor try to prescribe me Prilosec for *headaches*. People who start on, say, opiates or amphetamines, without knowing what they're getting into are foolish, RX or not.
Still, I'm quite for legalizing all drugs so that the pharma companies can simply sell recreational substances to those of age at pharmacies. The burden of responsibility lies with the individual consuming the drug. Just as the firearm owner is responsible for his use of a gun, and not the manufacturer.
THC may trigger psychoses so, no, they're not suitable with people with panic attacks. CBD, maybe.
Arms manufacturers selling armor? Or defense contractors who sell bullets also selling medical supplies?
This is Capital C Capitalism right here.
Hi, I am Capitalist Carl, and I am here to sell you the solution to the problem caused by the last product you bought from me, which was itself a solution to a previous problem, caused not be something you bought from me, but by something someone else bought from me earlier, in response to your use of something you bought from me also...
And on it goes.
Ditch big pharma, fund drug development at the fed tap managed by a private non-profit with a board of medical researchers
The structure you describe discourages risk-taking & disruption, and encourages groupthink. History has taught us that the engine of progress is decentralized innovation. As soon as you have some sort of central authority planning where innovation where come from then progress stagnates.
Capitalism isn't necessarily the only way to get there, but it's an extremely powerful way to harness human greed & status-seeking behavior. It's foolish to disregard that.
I say this article is true of the exact opposite. For those non Americans who know the difference between socialism/socialist democracies vs communism.
http://saveie6.com/
crack dealers hook you by coming into a area, low balling the price, running everyone out, then jacking up the price. Now, these opioid "dealers" get you hooked on their drug, NOW come up with a drug to get you off the drug they hooked you on in the first place. Wouldn't surprise me, people will get hooked on the drug, to get you hooked on the drug they wanted you on in the first place, then will have to get you off the drug, that was suppose to get you off the drug, they hooked you on.
Even if you did get addicted to buprenorphine, you'd be much better off.
CBD. Cannabidiol. People primarily associate marijuana with THC, which is the euphoria-inducing drug, but the other piece of marijuana is CBD, which is one, if not the most effective and non-addictive painkiller available.
After going through all the hoops in Canada to get a medical MJ license, I was disappointed as hell that CBD didn't do a damn thing for me for pain or depression. The two things CBD reportedly was supposed to help.
I half wonder if the people that claim it helps aren't just making this shit up to sell it.
Just like opiates don't help all types of pain, neither does CBD. It's not a magic cure all that can replace opiates in all cases. The official alternative is "sit there and suffer". Needless to say, good luck getting people to acknowledge all the suicides coming out of that.
Haha, how funny is it you were modded -1?
Peoplez need them pillz!!
Prime reason not to have privatized your prisons, it adds incentive to KEEP people in prison or PUT them in one. Bloody stupid idea, and I would bet the "three strikes" ruling came directly from lobbying from the people who own the prisons. The USA has the highest per capita amount of people in jail. As Jim Jeffries said, "Land of the free? Not so much" (I am paraphrasing).
There are three kinds of falsehood: the first is a 'fib,' the second is a downright lie, and the third is statistics.
https://science.slashdot.org/story/18/09/09/0233236/mindful-people-feel-less-pain-study-finds
And the comment is deleted instantly.. Tha ks Lenin for clicking that "delete/to the gulag" button
And likely more *expensive* drugs. Give me a break. This is pure, unadulterated, userous bullshit. Given that, I'm sure the FDA will give its approval tomorrow. People like this douche are psychopaths. Most people would improve rapidly if they got *off* the meds they were snookered into taking.
I half wonder if the people that claim it helps aren't just making this shit up to sell it.
They're not. It's either hit or miss, that's why say a person with migraines can be treated easily with stuff like Fiorinal c(asprin/barbiturates/codine/caffine) in one mix. And other people are on everything from sandomigraine to gabapentin and still have problems. It's why lyrica works for some people with nerve damage, and for others it increases the pain, or doesn't work at all. Why some people can get away with simply using tramadol for their pain, while others require oxycontin.
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Don't look now but...the Marijuana Industry is turning into the new drug pushers.
I'm sorry, but this info is bull. .. which also didn't really help much. gah, just thinking about this now has me cringe with pain. just stop with your untested preaching. you're seriously mistaken.
I've suffered severe fractures and in my body cbds were way more useless than the oxys
After a recent operation the first thing they did in the recovery room is shoot me full of opioids and I'm in commie Europe. When I went home I got a small number of oxycodone tablets for if things went off the deep end and the NSAIDs became useless (as they tend to do for serious pain). What's supposed to be the alternative?
The alternative?
Why indignation of course! At "big pharma"!
Well, OK, it won't kill pain, but it might distract you some ...
Once upon a time, this used to be called "Conflict of Interest".
They already make Suboxone, sublingual, and in film form, and Subutex as well as generic Burpenorphine, which comes without that very small amount of Narcan. Is this just PR for the epidemic that they started?
What's supposed to be the alternative?
Suffering. Pain will not kill you. If you ask some people, they say that pain is life. Suffering is not a problem for those who are merely watching the suffering.
"Someone needs to talk to the tree of liberty about its ghoulish drinking problem." by ohnocitizen
Suffering. Pain will not kill you.
I've been reading any stories about people with chronic pain who chose death when they were told they could no longer get relief from opioids.
If you ask some people, they say that pain is life. Suffering is not a problem for those who are merely watching the suffering.
Um, what?
Now if they could just come up with a scheme to drug boys when they're in elementary school (add, adhd, etc) and drug the girls when they are women (depression meds) they have a hell of an industry? Oh wait, that's what they already do.
If you want to restore my faith in "big pharma": Use 90% of all profits from the treatment (and I really mean gross - manufacturing cost as my definition of profit) as a charitable donation to opioid education and treatment. Additionally, stop all research into improving the existing potency of opioids. Finally, let doctors handle medicine, not lobbyists/police/sales agents.
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