It's still not worth it. That's ridiculous that someone would have to pay anywhere close to 50% taxes for those services. In the US I'm in the 25% Federal income tax bracket and my private health insurance plan and other benefits--including the employer subsidy would still only amount to about 30% of my my gross income. Adjusting for tax credits other deductions and my total tax burden ends up being probably closer to 18-20% anyway. I'll take quality of life + money any day.
I had a similar experience in a math class. The teacher introduced the concept of imaginary numbers. When I learned that imaginary numbers were just a man-made construct and do not really exist I angrily stormed out of the classroom and forsook science.
I have since repented and am currently employed as an electrical engineer. I am now quite comfortable with the concept of imaginary numbers. I'm glad I gave math a second try.
Except they are correct about destroying the economy. 70% of energy in the US is generated from fossil fuels. If scientists say we have only 30 years or so to become independent of oil/fossil fuels--I haven't been keeping track of the latest panic projections, but I remember some of them were about as ridiculous--then that certainly would be "death to America." Also don't conflate the three issues of preventing global warming, becoming independent of foreign energy imports and exhausting fossil fuel reserves.
As far as being liberators of Iraq. It depends on who you ask. I've met many Iraqi refugees that are very happy that Saddam was overthrown. There are a large number of Iranians who wish we would do the same there. Even many of the Iraqis causing trouble are happy that we came in because it upset the balance of power and gave them opportunities. I can't speak for the majority of Iraqis and I don't know that an accurate survey could be conducted. It depends on who you ask. If you have any military members in your family, ask them about their experiences if they've toured in Iraq, you will get a completely different perspective than what you hear reported in the news.
That's not necessarily work avoidance. When I get sick it is usually close to the weekend, either because I get behind on my sleep during the week and my immune system is dead by Friday, or I get no sleep on the weekend trying to fit in as many fun things as I can, usually physically exhausting myself---again increasing the chances of getting sick. That, in fact, happened just last weekend.
But it really stifles the creativity of the player by restricting actions to a very specific set of pre-programmed actions. You *must* farm for Vespene gas. you *must* collect crystals. There is little room for true creativity and adventuring. Today's FPS games are actually getting better at allowing this kind of freedom.
Yeah kind of like Chess. Who came up with that lousy game anyway? In particular pawns! Whose brilliant idea was it that the stupid little thing can only (under most circumstances) move one space foward at a time! Why can't we just have a polygynous king with 8 queens on the front row? It's no wonder that game was such a flop--no opportunity for creative expression or adventure of any kind!
I personally would much rather play a game with books full of rules on par with the IRS tax code and encyclopedias full of make-believe monsters and other elements that govern how my make-believe world will be run.
It's a shame that only 0.0001% of the world population plays D&D.
That was very helpful. Now I have a few more questions.
If the transferrin receptor is the target, how does this make it "cancer-specific"? Is this an abnormal receptor that would not be present in other cells? Or does this approach rely on the target selectively binding to the cancer cells because of the higher concentraiton of these receptors? If that's the case wouldn't we expect to see "collateral" damage (other cells)?
So they say this has the ability to silence genes. Yet the article says the treatment accomplished its purpose of splicing mRNA. Splicing mRNA!=gene silencing. This would mean this is a dose-dependent, reversible effect and not a permanent treatment. That makes it sound like someone would have to continually be on the drugs and when they stopped, then the effect would disappear and everything would return to pre-treatment conditions. During that time what's to stop the cancer from mutating and losing or altering those specific receptors.
I may have to actually read the primary literature, the summary article did a poor job of explaining any of this.
I don't mean to offend anyone, but why is this even such a big deal? Sure it's a new record, but why is it posted seemingly every week. Tomorrow we can expect another headline reading 3.6TeV.
Didn't they design this thing to run at much higher energy levels anyway?
Perhaps considering the frequency of problems they have been experiencing, the merit here is that it is, for the time being, running without something else exploding, leaking or burning up.
I'm more interested in the actual results of experiments when they finally get around to doing them.
This would come with the explicit expectation that these governments spend the money wisely, and steps are taken so that as little money as possible is wasted by corruption.
That is the problem plaguing the Bretton Woods Institutions and most other NGO international aid organizations since their inception. Certainly not a trivial problem. If you've got a solution then you'd immediately be appointed King of the World and given a Nobel prize to boot.
That bit about the Ethiopians is interesting, never heard that but can't say it's surprising!
I was lucky enough to have computer science classes taught in my highschool--incidentally that was at a small ghetto public school in Louisiana.
I really enjoyed the class and had an excellent teacher. I wouldn't have minded doing that as a career except I saw what kinds of other people were in the class with me and realized I would not want to work with those types my whole life. I also didn't want to work in a cubicle.
Had there been "cool" nerds in the class things would have been completely different. I never considered myself one of the super-cool kids, but I am fairly certain I was the only one in that class that had a girlfriend.
I also didn't want to end up working in a cube my whole life either--I discovered that while doing an engineering internship. And for the record, engineers are nerdy, but still much less nerdy that programmers. It's not hard to find cool engineers.
I once saw a fist-fight break out at a dissertation defense. It turned out just like Harrison Ford in The Fugitive confronting that clinician about falsifying medical records. Or maybe I'm getting the two confused. If it can happen in a movie I'm sure it can happen in real life, right?
Come on! Haven't you ever watched Star Trek or any other sci-fi show? You just have to modulate the frequency of the beam!
Seriously though, depending on the beam wavelength, you would have to find an appropriate reflective layer to match. A metallic coating may work well against visible and longer-wavelength beams, but if they move towards UV and X-ray, all bets are off. If you do have a metallic coating you can say goodbye to any possibilities of radar-stealth. Also depending on the material used, you probably wouldn't get total reflection anyway and it will be a function of beam angle of incidence and stuff.
So if you cooked food in the autoclave you'd never really have to worry about it going bad. You'd be eating sterile food! Although if food already went bad before, would toxins still be present? I think I remember reading something about E. Coli and similar bacterias getting people sick because of the immune response to LPS--a component of their cell walls. Maybe some of the biologists in the room can correct me.
Well I wouldn't want to charge my parents anything, even if I do get calls once a month about computer problems and have to walk them through every single step. Main reason being, what if my parents decided to send a bill my way for room and board and financial help they've given me, it could take me years to pay that off! It's a pretty sweet deal in my opinion.
The World of Goo payment experiment did not demonstrate that customers in general will pay far less than a product is worth. It just showed that customers will pay the value of a particular product to them. The World of Goo had been on sale for a long time prior to this experiment. Many people purchased the game previously at other set prices--those people that saw that product to them as being more valuable. I'm sure there were also a fair number of others who played the demo and decided the full version wasn't worth it (maybe when it cost $15.00 or so).
I will occasionally download pirated software. This is generally software or music that I really don't value or only need to use once, and really doesn't hold enough value to me to justify paying the full price. These are foundational principles of economics.
I am also the type of person who will decide I need a particular product, pick a few models and wait until I find one in my price range, or wait for prices to drop if I don't value it at it's current price (I'm still waiting on a logitech z 5500 to go down in price).
I could be wrong, but I think these are reasonable practices.
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It's still not worth it. That's ridiculous that someone would have to pay anywhere close to 50% taxes for those services. In the US I'm in the 25% Federal income tax bracket and my private health insurance plan and other benefits--including the employer subsidy would still only amount to about 30% of my my gross income. Adjusting for tax credits other deductions and my total tax burden ends up being probably closer to 18-20% anyway. I'll take quality of life + money any day.
I had a similar experience in a math class. The teacher introduced the concept of imaginary numbers. When I learned that imaginary numbers were just a man-made construct and do not really exist I angrily stormed out of the classroom and forsook science.
I have since repented and am currently employed as an electrical engineer. I am now quite comfortable with the concept of imaginary numbers. I'm glad I gave math a second try.
Except they are correct about destroying the economy. 70% of energy in the US is generated from fossil fuels. If scientists say we have only 30 years or so to become independent of oil/fossil fuels--I haven't been keeping track of the latest panic projections, but I remember some of them were about as ridiculous--then that certainly would be "death to America." Also don't conflate the three issues of preventing global warming, becoming independent of foreign energy imports and exhausting fossil fuel reserves.
As far as being liberators of Iraq. It depends on who you ask. I've met many Iraqi refugees that are very happy that Saddam was overthrown. There are a large number of Iranians who wish we would do the same there. Even many of the Iraqis causing trouble are happy that we came in because it upset the balance of power and gave them opportunities. I can't speak for the majority of Iraqis and I don't know that an accurate survey could be conducted. It depends on who you ask. If you have any military members in your family, ask them about their experiences if they've toured in Iraq, you will get a completely different perspective than what you hear reported in the news.
That's not necessarily work avoidance. When I get sick it is usually close to the weekend, either because I get behind on my sleep during the week and my immune system is dead by Friday, or I get no sleep on the weekend trying to fit in as many fun things as I can, usually physically exhausting myself---again increasing the chances of getting sick. That, in fact, happened just last weekend.
Now it's safe to say /. is work avoidance.
Remember the Elevator had the same type of history. There was a time when an attendant was there...
Geez how old are you?? I do not remember that at all!
Did you really just use Star Trek to support a normative claim about real life?
I've been waiting for this half my life!
But it really stifles the creativity of the player by restricting actions to a very specific set of pre-programmed actions. You *must* farm for Vespene gas. you *must* collect crystals. There is little room for true creativity and adventuring. Today's FPS games are actually getting better at allowing this kind of freedom.
Yeah kind of like Chess. Who came up with that lousy game anyway? In particular pawns! Whose brilliant idea was it that the stupid little thing can only (under most circumstances) move one space foward at a time! Why can't we just have a polygynous king with 8 queens on the front row? It's no wonder that game was such a flop--no opportunity for creative expression or adventure of any kind!
I personally would much rather play a game with books full of rules on par with the IRS tax code and encyclopedias full of make-believe monsters and other elements that govern how my make-believe world will be run.
It's a shame that only 0.0001% of the world population plays D&D.
...Richard Feynman. Oh wait.
That was very helpful. Now I have a few more questions.
If the transferrin receptor is the target, how does this make it "cancer-specific"? Is this an abnormal receptor that would not be present in other cells? Or does this approach rely on the target selectively binding to the cancer cells because of the higher concentraiton of these receptors? If that's the case wouldn't we expect to see "collateral" damage (other cells)?
Oops
edit: splicing mRNA = post-transcriptional gene silencing
So they say this has the ability to silence genes. Yet the article says the treatment accomplished its purpose of splicing mRNA. Splicing mRNA!=gene silencing. This would mean this is a dose-dependent, reversible effect and not a permanent treatment. That makes it sound like someone would have to continually be on the drugs and when they stopped, then the effect would disappear and everything would return to pre-treatment conditions. During that time what's to stop the cancer from mutating and losing or altering those specific receptors.
I may have to actually read the primary literature, the summary article did a poor job of explaining any of this.
I don't mean to offend anyone, but why is this even such a big deal? Sure it's a new record, but why is it posted seemingly every week. Tomorrow we can expect another headline reading 3.6TeV.
Didn't they design this thing to run at much higher energy levels anyway?
Perhaps considering the frequency of problems they have been experiencing, the merit here is that it is, for the time being, running without something else exploding, leaking or burning up.
I'm more interested in the actual results of experiments when they finally get around to doing them.
This would come with the explicit expectation that these governments spend the money wisely, and steps are taken so that as little money as possible is wasted by corruption.
That is the problem plaguing the Bretton Woods Institutions and most other NGO international aid organizations since their inception. Certainly not a trivial problem. If you've got a solution then you'd immediately be appointed King of the World and given a Nobel prize to boot.
That bit about the Ethiopians is interesting, never heard that but can't say it's surprising!
I was lucky enough to have computer science classes taught in my highschool--incidentally that was at a small ghetto public school in Louisiana.
I really enjoyed the class and had an excellent teacher. I wouldn't have minded doing that as a career except I saw what kinds of other people were in the class with me and realized I would not want to work with those types my whole life. I also didn't want to work in a cubicle.
Had there been "cool" nerds in the class things would have been completely different. I never considered myself one of the super-cool kids, but I am fairly certain I was the only one in that class that had a girlfriend.
I also didn't want to end up working in a cube my whole life either--I discovered that while doing an engineering internship. And for the record, engineers are nerdy, but still much less nerdy that programmers. It's not hard to find cool engineers.
I know, so true!
I once saw a fist-fight break out at a dissertation defense. It turned out just like Harrison Ford in The Fugitive confronting that clinician about falsifying medical records. Or maybe I'm getting the two confused. If it can happen in a movie I'm sure it can happen in real life, right?
The USA is the best nation in everything.
Come on! Haven't you ever watched Star Trek or any other sci-fi show? You just have to modulate the frequency of the beam!
Seriously though, depending on the beam wavelength, you would have to find an appropriate reflective layer to match. A metallic coating may work well against visible and longer-wavelength beams, but if they move towards UV and X-ray, all bets are off. If you do have a metallic coating you can say goodbye to any possibilities of radar-stealth. Also depending on the material used, you probably wouldn't get total reflection anyway and it will be a function of beam angle of incidence and stuff.
Seriously, that's a good way to make easy money. Auction off your genome!
Our lab submitted the grant just in time! Now we only need to sit around and wait for the check from Obama's pocketbook.
We already had a grant in the works, but once we found out about the stimulus money, quickly switched to one of these other special grants.
So if you cooked food in the autoclave you'd never really have to worry about it going bad. You'd be eating sterile food! Although if food already went bad before, would toxins still be present? I think I remember reading something about E. Coli and similar bacterias getting people sick because of the immune response to LPS--a component of their cell walls. Maybe some of the biologists in the room can correct me.
loses the remote in the couch or someone mistakes it for the TV remote?
That's what I was thinking. Sounds complicated! Leave it to the Japanese...
Well I wouldn't want to charge my parents anything, even if I do get calls once a month about computer problems and have to walk them through every single step. Main reason being, what if my parents decided to send a bill my way for room and board and financial help they've given me, it could take me years to pay that off! It's a pretty sweet deal in my opinion.
The World of Goo payment experiment did not demonstrate that customers in general will pay far less than a product is worth. It just showed that customers will pay the value of a particular product to them. The World of Goo had been on sale for a long time prior to this experiment. Many people purchased the game previously at other set prices--those people that saw that product to them as being more valuable. I'm sure there were also a fair number of others who played the demo and decided the full version wasn't worth it (maybe when it cost $15.00 or so).
I will occasionally download pirated software. This is generally software or music that I really don't value or only need to use once, and really doesn't hold enough value to me to justify paying the full price. These are foundational principles of economics.
I am also the type of person who will decide I need a particular product, pick a few models and wait until I find one in my price range, or wait for prices to drop if I don't value it at it's current price (I'm still waiting on a logitech z 5500 to go down in price).
I could be wrong, but I think these are reasonable practices.